Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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CLA3884 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A24327 | 22997020 | J Clin Ultrasound | Sonographic hepatorenal ratio: a noninvasive method to diagnose nonalcoholic steatosis. | 2012 | Details |
| A24338 | 22986520 | Cardiology | The association between nonalcoholic fatty liver disease, metabolic syndrome and arterial stiffness in nondiabetic, nonhypertensive individuals. | 2012 | Details |
| A24339 | 22986486 | Endocr J | Essential roles of growth hormone (GH) and insulin-like growth factor-I (IGF-I) in the liver. | 2012 | Details |
| A24341 | 22985537 | Clin Chim Acta | Identification of a support vector machine-based biomarker panel with high sensitivity and specificity for nonalcoholic steatohepatitis. | 2012 | Details |
| A24350 | 22978392 | Curr Drug Metab | Fatty acids - induced lipotoxicity and inflammation. | 2012 | Details |
| A24353 | 22974598 | J Pediatr Surg | Patterns of surgical weight loss and resolution of metabolic abnormalities in superobese bariatric adolescents. | 2012 | Details |
| A24359 | 22969777 | Cardiorenal Med | Relationship between Changes in Plasma Adiponectin Concentration and Insulin Sensitivity after Niacin Therapy. | 2012 | Details |
| A24362 | 22966992 | Aliment Pharmacol Ther | Review article: is non-alcoholic fatty liver disease a spectrum, or are steatosis and non-alcoholic steatohepatitis distinct conditions? | 2012 | Details |
| A24375 | 22960565 | J Proteomics | Proteomic analysis of liver mitochondria of apolipoprotein E knockout mice treated with metformin. | 2012 | Details |
| A24389 | 22942630 | Int J Angiol | Carotid intima-media thickness and liver histology in hemodialysis patients with nonalcoholic Fatty liver disease. | 2011 | Details |
| A24401 | 22934096 | Front Immunol | Resolution of inflammation in obesity-induced liver disease. | 2012 | Details |
| A24410 | 22927922 | PLoS One | Cannabinoid receptor type 2 functional variant influences liver damage in children with non-alcoholic fatty liver disease. | 2012 | Details |
| A24415 | 22922605 | Int J Mol Med | Isoform-specific alanine aminotransferase measurement can distinguish hepatic from extrahepatic injury in humans. | 2012 | Details |
| A24423 | 22913202 | Eur Rev Med Pharmacol Sci | Glycine alleviates liver injury induced by deficiency in methionine and or choline in rats. | 2012 | Details |
| A24425 | 22911170 | J Gastroenterol | Clinicopathological features of liver injury in patients with type 2 diabetes mellitus and comparative study of histologically proven nonalcoholic fatty liver diseases with or without type 2 diabetes mellitus. | 2012 | Details |
| A24432 | 22899556 | Hepatology | Determination of reliability criteria for liver stiffness evaluation by transient elastography. | 2013 | Details |
| A24437 | 22898281 | Zhongguo Dang Dai Er Ke Za Zhi | [Quantitative assessment of intrahepatic fat content in children and adolescents with non-alcoholic fatty liver disease]. | 2012 | Details |
| A24455 | 22876924 | Curr Med Chem | Adiponectin: key player in the adipose tissue-liver crosstalk. | 2012 | Details |
| A24467 | 22868011 | J Coll Physicians Surg Pak | Serum cholesterol: could it be a sixth parameter of Child-Pugh scoring system in cirrhotics due to viral hepatitis? | 2012 | Details |
| A24484 | 22848440 | PLoS One | Gallstone disease is associated with more severe liver damage in patients with non-alcoholic fatty liver disease. | 2012 | Details |
| A24503 | 22826613 | World J Gastroenterol | Multicausality in fatty liver disease: is there a rationale to distinguish between alcoholic and non-alcoholic origin? | 2012 | Details |
| A24508 | 22824482 | Clin Liver Dis | Is nonalcoholic fatty liver disease in children the same disease as in adults? | 2012 | Details |
| A24518 | 22820478 | J Hepatol | Regular coffee but not espresso drinking is protective against fibrosis in a cohort mainly composed of morbidly obese European women with NAFLD undergoing bariatric surgery. | 2012 | Details |
| A24536 | 22792295 | PLoS One | The PNPLA3 rs738409 G-allele associates with reduced fasting serum triglyceride and serum cholesterol in Danes with impaired glucose regulation. | 2012 | Details |
| A24538 | 22790124 | Intern Med | Non-alcoholic fatty liver disease is an independent predictor for macroangiopathy in Japanese type 2 diabetic patients: a cross-sectional study. | 2012 | Details |
| A24540 | 22788090 | Rom J Intern Med | Non-alcoholic fatty liver disease and the statins treatment. | 2012 | Details |
| A24557 | 22751691 | Diabetes | Effects of aerobic versus resistance exercise without caloric restriction on abdominal fat, intrahepatic lipid, and insulin sensitivity in obese adolescent boys: a randomized, controlled trial. | 2012 | Details |
| A24566 | 22742931 | J Gastroenterol Hepatol | Functional role of peroxisome-proliferator-activated receptor γ in hepatocellular carcinoma. | 2012 | Details |
| A24576 | 22735219 | Rev Assoc Med Bras (1992) | Association between non-alcoholic fatty liver disease and liver function/injury markers with metabolic syndrome components in class III obese individuals. | 2013 | Details |
| A24583 | 22724878 | Arch Iran Med | Sampling error in histopathology findings of nonalcoholic fatty liver disease: a post mortem liver histology study. | 2012 | Details |
| A24589 | 22719876 | PLoS One | Genetic polymorphisms of the human PNPLA3 gene are strongly associated with severity of non-alcoholic fatty liver disease in Japanese. | 2012 | Details |
| A24598 | 22707395 | Hepatology | Histopathological algorithm and scoring system for evaluation of liver lesions in morbidly obese patients. | 2012 | Details |
| A24609 | 22694047 | Clin Transplant | Complications associated with liver transplantation in the obese recipient. | 2012 | Details |
| A24615 | 22689144 | J Bioenerg Biomembr | Dietary fatty acids modulate liver mitochondrial cardiolipin content and its fatty acid composition in rats with non alcoholic fatty liver disease. | 2012 | Details |
| A24641 | 22659415 | Biochem Biophys Res Commun | GH-independent IGF-I action is essential to prevent the development of nonalcoholic steatohepatitis in a GH-deficient rat model. | 2012 | Details |
| A24647 | 22652341 | Drug Discov Today | Farnesoid X receptor targeting to treat nonalcoholic steatohepatitis. | 2012 | Details |
| A24652 | 22648049 | Eur Radiol | Detection of non-alcoholic steatohepatitis in patients with morbid obesity before bariatric surgery: preliminary evaluation with acoustic radiation force impulse imaging. | 2012 | Details |
| A24660 | 22644007 | Cir Cir | Prevalence of nonalcoholic fatty liver disease in subjects with metabolic syndrome. | 2012 | Details |
| A24682 | 22612998 | J Hepatol | Validation of liver fibrosis biomarker (FibroTest) for assessing liver fibrosis progression: proof of concept and first application in a large population. | 2012 | Details |
| A24683 | 22611049 | Hepatology | Lower serum hepcidin and greater parenchymal iron in nonalcoholic fatty liver disease patients with C282Y HFE mutations. | 2012 | Details |
| A24697 | 22588441 | Ann Saudi Med | Epidemiological, clinical, and biochemical characteristics of Saudi patients with nonalcoholic fatty liver disease: a hospital-based study. | 2012 | Details |
| A24698 | 22586470 | PLoS One | Hepcidin expression in iron overload diseases is variably modulated by circulating factors. | 2012 | Details |
| A24709 | 22576023 | J Gastroenterol | Pathophysiological analysis of nonalcoholic fatty liver disease by evaluation of fatty liver changes and blood flow using xenon computed tomography: can early-stage nonalcoholic steatohepatitis be distinguished from simple steatosis? | 2012 | Details |
| A24721 | 22561871 | Toxicol Appl Pharmacol | Plasma microRNAs are sensitive indicators of inter-strain differences in the severity of liver injury induced in mice by a choline- and folate-deficient diet. | 2012 | Details |
| A24727 | 22554516 | Biochem Biophys Res Commun | Ezetimibe reduces fatty acid quantity in liver and decreased inflammatory cell infiltration and improved NASH in medaka model. | 2012 | Details |
| A24728 | 22554494 | Brain Behav Immun | Exercise training attenuates hepatic inflammation, fibrosis and macrophage infiltration during diet induced-obesity in mice. | 2012 | Details |
| A24771 | 22519948 | Scand J Gastroenterol | A prospective evaluation of the role of transient elastography for the detection of hepatic fibrosis in type 2 diabetes without overt liver disease. | 2012 | Details |
| A24776 | 22509083 | World J Gastroenterol | Identification of individuals with non-alcoholic fatty liver disease by the diagnostic criteria for the metabolic syndrome. | 2012 | Details |
| A24789 | 22490991 | J Endocrinol Invest | Non-alcoholic fatty liver disease is independently associated with left ventricular hypertrophy in hypertensive Type 2 diabetic individuals. | 2012 | Details |
| A24801 | 22476124 | Rev Gastroenterol Peru | [Validation of an instrument to measure the level of knowledge of non alcoholic fatty liver in general medical doctors in Chiclayo, Perú]. | 2012 | Details |
| A24804 | 22474039 | Diabetes Care | Multiorgan insulin sensitivity in lean and obese subjects. | 2012 | Details |
| A24805 | 22470565 | PLoS One | Internalization of modified lipids by CD36 and SR-A leads to hepatic inflammation and lysosomal cholesterol storage in Kupffer cells. | 2012 | Details |
| A24811 | 22468959 | Free Radic Res | Fatty liver induced by free radicals and lipid peroxidation. | 2012 | Details |
| A24813 | 22468076 | World J Gastroenterol | Genetically modified mouse models for the study of nonalcoholic fatty liver disease. | 2012 | Details |
| A24817 | 22467327 | J Clin Lab Anal | Visfatin levels in nonalcoholic fatty liver disease. | 2012 | Details |
| A24830 | 22455888 | Zhonghua Bing Li Xue Za Zhi | [Mechanism of hepatocyte apoptosis in rats with liver fibrosis induced by lipogenic methionine-choline-deficient diet]. | 2012 | Details |
| A24853 | 22431959 | PLoS One | Performance of biomarkers FibroTest, ActiTest, SteatoTest, and NashTest in patients with severe obesity: meta analysis of individual patient data. | 2012 | Details |
| A24854 | 22431131 | Hepatology | Effect of colesevelam on liver fat quantified by magnetic resonance in nonalcoholic steatohepatitis: a randomized controlled trial. | 2012 | Details |
| A24874 | 22418883 | Semin Liver Dis | Nonalcoholic fatty liver disease: pathologic patterns and biopsy evaluation in clinical research. | 2012 | Details |
| A24906 | 22374640 | Diabetes Care | Prevalence of prediabetes and diabetes and metabolic profile of patients with nonalcoholic fatty liver disease (NAFLD). | 2012 | Details |
| A24908 | 22373558 | Ned Tijdschr Geneeskd | [Consequences of non-alcoholic fatty liver disease still unclear]. | 2012 | Details |
| A24922 | 22359625 | PLoS One | Liver and muscle in morbid obesity: the interplay of fatty liver and insulin resistance. | 2012 | Details |
| A24936 | 22340817 | BMC Gastroenterol | Involvement of a periodontal pathogen, Porphyromonas gingivalis on the pathogenesis of non-alcoholic fatty liver disease. | 2012 | Details |
| A24953 | 22319522 | Exp Diabetes Res | Pentoxifylline attenuates methionine- and choline-deficient-diet-induced steatohepatitis by suppressing TNF-α expression and endoplasmic reticulum stress. | 2012 | Details |
| A24964 | 22307032 | Gastroenterology | Hepatic cannabinoid receptor-1 mediates diet-induced insulin resistance via inhibition of insulin signaling and clearance in mice. | 2012 | Details |
| A24969 | 22297300 | Am J Physiol Endocrinol Metab | Adiponectin promoter activator NP-1 reduces body weight and hepatic steatosis in high-fat diet-fed animals. | 2012 | Details |
| A24971 | 22294826 | World J Gastroenterol | Aging is a risk factor of nonalcoholic fatty liver disease in premenopausal women. | 2012 | Details |
| A24991 | 22271511 | Hepatology | Nonalcoholic fatty liver disease is associated with coronary artery calcification. | 2012 | Details |
| A24999 | 22259190 | J Nutr | Apo-10'-lycopenoic acid, a lycopene metabolite, increases sirtuin 1 mRNA and protein levels and decreases hepatic fat accumulation in ob/ob mice. | 2012 | Details |
| A25001 | 22257474 | J Dig Dis | Liver X receptors bridge hepatic lipid metabolism and inflammation. | 2012 | Details |
| A25006 | 22251279 | Hepatol Res | Usefulness of Technetium-99 m-2-methoxy-isobutyl-isonitrile liver scintigraphy for evaluating disease activity of non-alcoholic fatty liver disease. | 2012 | Details |
| A25016 | 22245962 | Clin Gastroenterol Hepatol | Independent association between nonalcoholic fatty liver disease and cardiovascular disease in the US population. | 2012 | Details |
| A25018 | 22242926 | Metab Syndr Relat Disord | Docosahexaenoic acid prevents trans-10, cis-12-conjugated linoleic acid-induced nonalcoholic fatty liver disease in mice by altering expression of hepatic genes regulating fatty acid synthesis and oxidation. | 2012 | Details |
| A25020 | 22240370 | Clin Hemorheol Microcirc | Elevated hematocrit in nonalcoholic fatty liver disease: a potential cause for the increased risk of cardiovascular disease? | 2012 | Details |
| A25026 | 22236001 | Clin Exp Immunol | Oral administration of immunoglobulin G-enhanced colostrum alleviates insulin resistance and liver injury and is associated with alterations in natural killer T cells. | 2012 | Details |
| A25041 | 22221544 | BMC Gastroenterol | Validation of the FIB4 index in a Japanese nonalcoholic fatty liver disease population. | 2012 | Details |
| A25048 | 22215535 | IUBMB Life | Association of nonalcoholic fatty liver disease with a single nucleotide polymorphism on the gene encoding leptin receptor. | 2012 | Details |
| A25056 | 33907358 | J Proteomics Bioinform | High Fat Diet-Induced Changes in Hepatic Protein Abundance in Mice. | 2012 | Details |
| A25084 | 22183894 | Mol Med | Glycine N-methyltransferase deficiency affects Niemann-Pick type C2 protein stability and regulates hepatic cholesterol homeostasis. | 2012 | Details |
| A25086 | 22183689 | Hepatology | Effect of adipose tissue insulin resistance on metabolic parameters and liver histology in obese patients with nonalcoholic fatty liver disease. | 2012 | Details |
| A25140 | 22147010 | Endocrinology | Thyroid hormone receptor-α gene knockout mice are protected from diet-induced hepatic insulin resistance. | 2011 | Details |
| A25157 | 22126026 | Adv Clin Chem | Iron overload in nonalcoholic steatohepatitis. | 2011 | Details |
| A25159 | 22125617 | PLoS One | Coordinated defects in hepatic long chain fatty acid metabolism and triglyceride accumulation contribute to insulin resistance in non-human primates. | 2011 | Details |
| A25188 | 22105730 | Minerva Gastroenterol Dietol | Nonalcoholic fatty liver disease: the concept and confusion. | 2011 | Details |
| A25191 | 22103753 | Pharm Biol | Fish oil improves lipid metabolism and ameliorates inflammation in patients with metabolic syndrome: impact of nonalcoholic fatty liver disease. | 2011 | Details |
| A25202 | 22097199 | Zhongguo Zhong Xi Yi Jie He Za Zhi | [Study on the distribution and characteristics of Chinese medicine syndrome in patients with nonalcoholic fatty liver disease]. | 2011 | Details |
| A25203 | 22096112 | Eur J Endocrinol | Recent advances in cardiovascular aspects of polycystic ovary syndrome. | 2011 | Details |
| A25220 | 22083307 | Mol Cells | Time-dependent changes in lipid metabolism in mice with methionine choline deficiency-induced fatty liver disease. | 2011 | Details |
| A25258 | 22035383 | Hepatol Res | Histopathological characteristics of non-alcoholic fatty liver disease in children: Comparison with adult cases. | 2011 | Details |
| A25263 | 22027576 | J Hepatol | The value of pre-operative magnetic resonance spectroscopy in the assessment of steatohepatitis in patients with colorectal liver metastasis. | 2011 | Details |
| A25278 | 22013810 | Zhongguo Zhong Xi Yi Jie He Za Zhi | [The key target of Chinese medicine treatment on alcoholic and nonalcoholic fatty liver disease: the gut]. | 2011 | Details |
| A25293 | 21988593 | Diabet Med | Biomarkers for diabetes prediction, pathogenesis or pharmacotherapy guidance? Past, present and future possibilities. | 2012 | Details |
| A25309 | 21971896 | Sao Paulo Med J | Steatosis of indeterminate cause in a pediatric group: is it a primary mitochondrial hepatopathy? | 2011 | Details |
| A25312 | 21967816 | Am J Pathol | Insulin resistance and metabolic hepatocarcinogenesis with parent-of-origin effects in A×B mice. | 2011 | Details |
| A25315 | 21963564 | Biochim Biophys Acta | Liver triacylglycerol lipases. | 2011 | Details |
| A25317 | 21962038 | BMC Public Health | Metabolically healthy and unhealthy obesity phenotypes in the general population: the FIN-D2D Survey. | 2011 | Details |
| A25337 | 21948570 | Turk J Gastroenterol | A new risk factor for the development of non-alcoholic fatty liver disease: HLA complex genes. | 2011 | Details |
| A25338 | 21948338 | Dig Dis Sci | Activation of liver X receptors attenuates endotoxin-induced liver injury in mice with nonalcoholic fatty liver disease. | 2011 | Details |
| A25369 | 21912450 | World J Gastroenterol | Pediatric nonalcoholic fatty liver disease, metabolic syndrome and cardiovascular risk. | 2011 | Details |
| A25370 | 21912108 | Ann Nutr Metab | Early-onset metabolic syndrome in prepubertal obese children and the possible role of alanine aminotransferase as marker of metabolic syndrome. | 2011 | Details |