Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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oxidative stress3585 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A24475 | 22857151 | Pharm Biol | Antioxidative effects of Alisma orientale extract in palmitate-induced cellular injury. | 2012 | Details |
| A24479 | 22854109 | Metabolism | High-fat, high-fructose diet induces hepatic iron overload via a hepcidin-independent mechanism prior to the onset of liver steatosis and insulin resistance in mice. | 2012 | Details |
| A24487 | 22846353 | Clin Calcium | [Magnesium and liver]. | 2012 | Details |
| A24492 | 22843123 | Endocrine | Administration of ghrelin improves inflammation, oxidative stress, and apoptosis during and after non-alcoholic fatty liver disease development. | 2012 | Details |
| A24526 | 22808787 | Eksp Klin Gastroenterol | [Nutrition mistakes in patients with nonalcoholic fatty liver disease and the ways of correction]. | 2012 | Details |
| A24553 | 22753171 | Hepatology | Elovl6 promotes nonalcoholic steatohepatitis. | 2012 | Details |
| A24571 | 22739374 | J Nutr | Menhaden oil decreases high-fat diet-induced markers of hepatic damage, steatosis, inflammation, and fibrosis in obese Ldlr-/- mice. | 2012 | Details |
| A24577 | 22734967 | Clin Sci (Lond) | Kupffer cell depletion attenuates leptin-mediated methoxamine-stimulated portal perfusion pressure and thromboxane A2 release in a rodent model of NASH-cirrhosis. | 2012 | Details |
| A24595 | 22713601 | Lipids Health Dis | Fructose-rich diet leads to reduced aerobic capacity and to liver injury in rats. | 2012 | Details |
| A24614 | 22690236 | Hepat Mon | Heme oxygenase-1 mRNA expression in egyptian patients with chronic liver disease. | 2012 | Details |
| A24621 | 22683933 | Toxicol In Vitro | Effects of palmitic acid on TNF-α-induced cytotoxicity in SK-Hep-1 cells. | 2012 | Details |
| A24637 | 22668639 | J Hepatol | Critical role of cytochrome P450 2E1 (CYP2E1) in the development of high fat-induced non-alcoholic steatohepatitis. | 2012 | Details |
| A24641 | 22659415 | Biochem Biophys Res Commun | GH-independent IGF-I action is essential to prevent the development of nonalcoholic steatohepatitis in a GH-deficient rat model. | 2012 | Details |
| A24658 | 25755421 | J Clin Exp Hepatol | Non-alcoholic Fatty Liver Disease: East Versus West. | 2012 | Details |
| A24667 | 22633783 | J Pediatr | The effect of cysteamine bitartrate on adiponectin multimerization in non-alcoholic fatty liver disease and healthy subjects. | 2012 | Details |
| A24668 | 22633099 | Transl Res | Silibinin modulates lipid homeostasis and inhibits nuclear factor kappa B activation in experimental nonalcoholic steatohepatitis. | 2012 | Details |
| A24688 | 22609053 | Trends Endocrinol Metab | Role of ceramides in nonalcoholic fatty liver disease. | 2012 | Details |
| A24737 | 22546752 | Eur J Gastroenterol Hepatol | γ-Glutamyl transferase: a marker of nonalcoholic fatty liver disease in patients with the metabolic syndrome. | 2012 | Details |
| A24741 | 22545719 | Clin Sci (Lond) | Lack of CC chemokine ligand 2 differentially affects inflammation and fibrosis according to the genetic background in a murine model of steatohepatitis. | 2012 | Details |
| A24744 | 22544329 | Cell Cycle | The DNA damage checkpoint protein ATM promotes hepatocellular apoptosis and fibrosis in a mouse model of non-alcoholic fatty liver disease. | 2012 | Details |
| A24750 | 22538930 | Eur J Nutr | Ellagic acid attenuates high-carbohydrate, high-fat diet-induced metabolic syndrome in rats. | 2012 | Details |
| A24752 | 22536512 | Int J Hepatol | Paraoxonase activity and expression is modulated by therapeutics in experimental rat nonalcoholic Fatty liver disease. | 2012 | Details |
| A24753 | 22535755 | J Nutr | Quercetin ameliorates cardiovascular, hepatic, and metabolic changes in diet-induced metabolic syndrome in rats. | 2012 | Details |
| A24779 | 22505328 | Hepatology | Hydrogen-rich water prevents progression of nonalcoholic steatohepatitis and accompanying hepatocarcinogenesis in mice. | 2012 | Details |
| A24780 | 22505276 | Hepatology | Pentoxifylline decreases oxidized lipid products in nonalcoholic steatohepatitis: new evidence on the potential therapeutic mechanism. | 2012 | Details |
| A24786 | 22496902 | PLoS One | Effect of dietary advanced glycation end products on mouse liver. | 2012 | Details |
| A24794 | 22484459 | Clin Biochem | Role of mitochondria in nonalcoholic fatty liver disease--from origin to propagation. | 2012 | Details |
| A24806 | 22469867 | Int J Mol Med | Therapeutic effects of angiotensin II type 1 receptor blocker, irbesartan, on non-alcoholic steatohepatitis using FLS-ob/ob male mice. | 2012 | Details |
| A24811 | 22468959 | Free Radic Res | Fatty liver induced by free radicals and lipid peroxidation. | 2012 | Details |
| A24818 | 22467277 | Hepatology | Hepatic progenitor cells activation, fibrosis, and adipokines production in pediatric nonalcoholic fatty liver disease. | 2012 | Details |
| A24824 | 22464551 | Nutrition | Non-alcoholic fatty liver disease in children now: lifestyle changes and pharmacologic treatments. | 2012 | Details |
| A24825 | 22462240 | J Tradit Chin Med | Dangfei liganning capsules attenuate the susceptibility of rat nonalcoholic fatty liver to carbon tetrachloride toxicity. | 2011 | Details |
| A24828 | 22457860 | J Gastrointestin Liver Dis | Serum ferritin levels do not predict the stage of underlying non-alcoholic fatty liver disease. | 2012 | Details |
| A24830 | 22455888 | Zhonghua Bing Li Xue Za Zhi | [Mechanism of hepatocyte apoptosis in rats with liver fibrosis induced by lipogenic methionine-choline-deficient diet]. | 2012 | Details |
| A24871 | 22418886 | Semin Liver Dis | Nonalcoholic steatohepatitis and noncirrhotic hepatocellular carcinoma: fertile soil. | 2012 | Details |
| A24878 | 22408414 | Int J Mol Sci | Coenzyme Q metabolism is disturbed in high fat diet-induced non-alcoholic fatty liver disease in rats. | 2012 | Details |
| A24879 | 22408036 | Eur Heart J | Non-alcoholic fatty liver disease: a new and important cardiovascular risk factor? | 2012 | Details |
| A24899 | 22381945 | Phytomedicine | Prevention of free fatty acid-induced lipid accumulation, oxidative stress, and cell death in primary hepatocyte cultures by a Gynostemma pentaphyllum extract. | 2012 | Details |
| A24900 | 22380754 | BMC Gastroenterol | Effect of intracellular lipid accumulation in a new model of non-alcoholic fatty liver disease. | 2012 | Details |
| A24902 | 22378061 | Hepatology | Chronic inflammation, immune escape, and oncogenesis in the liver: a unique neighborhood for novel intersections. | 2012 | Details |
| A24903 | 22375551 | J Biomed Sci | Amelioration of diet-induced nonalcoholic steatohepatitis in rats by Mn-salen complexes via reduction of oxidative stress. | 2012 | Details |
| A24910 | 22372457 | Histopathology | The epidemiology, pathogenesis and histopathology of fatty liver disease. | 2012 | Details |
| A24915 | 22364184 | J Agric Food Chem | Synergistic effect of cyanidin and PPAR agonist against nonalcoholic steatohepatitis-mediated oxidative stress-induced cytotoxicity through MAPK and Nrf2 transduction pathways. | 2012 | Details |
| A24937 | 22340678 | Liver Int | Identification of liver proteins altered by type 2 diabetes mellitus in obese subjects. | 2012 | Details |
| A24948 | 22327056 | Obesity (Silver Spring) | Lipoic acid improves mitochondrial function in nonalcoholic steatosis through the stimulation of sirtuin 1 and sirtuin 3. | 2012 | Details |
| A24951 | 22326434 | Gastroenterology | Role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis: pathophysiology and clinical implications. | 2012 | Details |
| A24957 | 22313887 | Zhong Xi Yi Jie He Xue Bao | [Effects of the mixture of Swertia pseudochinensis Hara and Silybum marianum Gaertn extracts on CCl(4)-induced liver injury in rats with non-alcoholic fatty liver disease]. | 2012 | Details |
| A24960 | 22310735 | J Gastroenterol | Inflammation and fibrogenesis in steatohepatitis. | 2012 | Details |
| A24986 | 22278044 | Eur J Nutr | Garlic-derived S-allylmercaptocysteine is a hepato-protective agent in non-alcoholic fatty liver disease in vivo animal model. | 2012 | Details |
| A25021 | 22240297 | J Proteomics | Changes in hepatic protein expression in spontaneously hypertensive rats suggest early stages of non-alcoholic fatty liver disease. | 2012 | Details |
| A25023 | 22239625 | Curr Vasc Pharmacol | Non-alcoholic fatty liver disease in type 2 diabetes: pathogenesis and treatment options. | 2012 | Details |
| A25031 | 22228717 | Diabetes | TIMP3 overexpression in macrophages protects from insulin resistance, adipose inflammation, and nonalcoholic fatty liver disease in mice. | 2012 | Details |
| A25038 | 22224077 | Hepat Mon | Obesity and air pollution: global risk factors for pediatric non-alcoholic fatty liver disease. | 2011 | Details |
| A25068 | 22198578 | Clin Biochem | Unconjugated hyperbilirubinemia in patients with non-alcoholic fatty liver disease: a favorable endogenous response. | 2011 | Details |
| A25070 | 22197629 | Dig Liver Dis | Silibinin improves hepatic and myocardial injury in mice with nonalcoholic steatohepatitis. | 2011 | Details |
| A25115 | 22157544 | J Nutr | Green tea extract suppresses NFκB activation and inflammatory responses in diet-induced obese rats with nonalcoholic steatohepatitis. | 2011 | Details |
| A25120 | 22155236 | Biochem Biophys Res Commun | Theaflavin attenuates ischemia-reperfusion injury in a mouse fatty liver model. | 2011 | Details |
| A25121 | 22154950 | Dig Liver Dis | Inverse correlation between plasma oxysterol and LDL-cholesterol levels in hepatitis C virus-infected patients. | 2011 | Details |
| A25122 | 22154902 | Life Sci | Alpha-lipoic acid attenuates methionine choline deficient diet-induced steatohepatitis in C57BL/6 mice. | 2011 | Details |
| A25134 | 22152305 | Cell Metab | Excessive hepatic mitochondrial TCA cycle and gluconeogenesis in humans with nonalcoholic fatty liver disease. | 2011 | Details |
| A25155 | 22129639 | J Nutr Biochem | The role of fructose-enriched diets in mechanisms of nonalcoholic fatty liver disease. | 2011 | Details |
| A25157 | 22126026 | Adv Clin Chem | Iron overload in nonalcoholic steatohepatitis. | 2011 | Details |
| A25160 | 22124850 | Curr Gastroenterol Rep | Iron metabolism in Nonalcoholic Fatty Liver Disease. | 2012 | Details |
| A25162 | 22121808 | Zhongguo Zhong Yao Za Zhi | [Effect of total alkaloids of Rubus alceaefolius on oxidative stress in rats with non-alcoholic fatty liver disease]. | 2011 | Details |
| A25179 | 22110476 | Exp Diabetes Res | Diagnosis and evaluation of nonalcoholic fatty liver disease. | 2011 | Details |
| A25189 | 22105311 | Eur J Nutr | Cardioprotective and hepatoprotective effects of ellagitannins from European oak bark (Quercus petraea L.) extract in rats. | 2011 | Details |
| A25191 | 22103753 | Pharm Biol | Fish oil improves lipid metabolism and ameliorates inflammation in patients with metabolic syndrome: impact of nonalcoholic fatty liver disease. | 2011 | Details |
| A25200 | 22097893 | Liver Int | Neutrophil to lymphocyte ratio: a new marker for predicting steatohepatitis and fibrosis in patients with nonalcoholic fatty liver disease. | 2011 | Details |
| A25209 | 22093454 | Liver Int | Prevention of free fatty acid-induced hepatic lipotoxicity by carnitine via reversal of mitochondrial dysfunction. | 2011 | Details |
| A25212 | 22093324 | Liver Int | Antioxidants as therapeutic agents for liver disease. | 2011 | Details |
| A25222 | 22082335 | Chem Res Toxicol | Glutathione-deficient mice are susceptible to TCDD-Induced hepatocellular toxicity but resistant to steatosis. | 2011 | Details |
| A25225 | 22081873 | Comp Hepatol | The effect of cocoa supplementation on hepatic steatosis, reactive oxygen species and LFABP in a rat model of NASH. | 2011 | Details |
| A25230 | 22074433 | Curr Pharm Des | Liver enzymes: potential cardiovascular risk markers? | 2011 | Details |
| A25236 | 22064361 | Free Radic Biol Med | Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis. | 2011 | Details |
| A25269 | 22024078 | Hepatogastroenterology | Upregulation of Nrf2 expression in non-alcoholic fatty liver and steatohepatitis. | 2012 | Details |
| A25272 | 22020821 | Hepatol Int | Non-alcoholic fatty liver disease: is iron relevant? | 2011 | Details |
| A25276 | 22015687 | Clin Biochem | Some inflammatory cytokine levels, iron metabolism and oxidan stress markers in subjects with nonalcoholic steatohepatitis. | 2011 | Details |
| A25281 | 22011249 | DNA Cell Biol | Association of genetic polymorphisms of glutathione-S-transferase genes (GSTT1, GSTM1, and GSTP1) and susceptibility to nonalcoholic fatty liver disease in Zahedan, Southeast Iran. | 2011 | Details |
| A25283 | 22008843 | Food Funct | The importance of the long-chain polyunsaturated fatty acid n-6/n-3 ratio in development of non-alcoholic fatty liver associated with obesity. | 2011 | Details |
| A25284 | 22002020 | Curr Opin Lipidol | Nonalcoholic steatohepatitis: the therapeutic challenge of a global epidemic. | 2011 | Details |
| A25285 | 21999619 | Biomarkers | Erythrocyte antioxidant defenses as a potential biomarker of liver mitochondrial status in different oxidative conditions. | 2011 | Details |
| A25287 | 21994008 | Hepatology | Vitamin D deficiency in obese rats exacerbates nonalcoholic fatty liver disease and increases hepatic resistin and Toll-like receptor activation. | 2012 | Details |
| A25292 | 21989716 | Mol Cell Biochem | Ω3-Polyunsaturated fatty acids prevent lipoperoxidation, modulate antioxidant enzymes, and reduce lipid content but do not alter glycogen metabolism in the livers of diabetic rats fed on a high fat thermolyzed diet. | 2011 | Details |
| A25322 | 21957160 | Am J Physiol Regul Integr Comp Physiol | Experimental evidence for therapeutic potential of taurine in the treatment of nonalcoholic fatty liver disease. | 2011 | Details |
| A25334 | 21951869 | Hepatol Res | Clinicopathological features of non-alcoholic fatty liver disease. | 2011 | Details |
| A25341 | 21947639 | Nutr Clin Pract | Nonalcoholic fatty liver disease: a review of the spectrum of disease, diagnosis, and therapy. | 2011 | Details |
| A25345 | 21943357 | Nutr Metab (Lond) | The intake of high fat diet with different trans fatty acid levels differentially induces oxidative stress and non alcoholic fatty liver disease (NAFLD) in rats. | 2011 | Details |
| A25349 | 21939732 | Mol Cell Endocrinol | PPARG gene Pro12Ala variant contributes to the development of non-alcoholic fatty liver in middle-aged and older Chinese population. | 2011 | Details |
| A25357 | 21931690 | PLoS One | Upregulation of hemoglobin expression by oxidative stress in hepatocytes and its implication in nonalcoholic steatohepatitis. | 2011 | Details |
| A25360 | 21929649 | J Gastroenterol Hepatol | Peroxisome proliferator-activated receptor-α agonist, Wy 14,643, improves metabolic indices, steatosis and ballooning in diabetic mice with non-alcoholic steatohepatitis. | 2012 | Details |
| A25376 | 21910083 | Adv Exp Med Biol | Adipose tissue and ceramide biosynthesis in the pathogenesis of obesity. | 2011 | Details |
| A25380 | 21906580 | Am J Pathol | Melanocortin 4 receptor-deficient mice as a novel mouse model of nonalcoholic steatohepatitis. | 2011 | Details |
| A25403 | 21886908 | Sci Pharm | Type 2 Diabetes Mellitus-Induced Hyperglycemia in Patients with NAFLD and Normal LFTs: Relationship to Lipid Profile, Oxidative Stress and Pro-Inflammatory Cytokines. | 2011 | Details |
| A25410 | 21881966 | Metab Brain Dis | Non-alcoholic fatty liver induces insulin resistance and metabolic disorders with development of brain damage and dysfunction. | 2011 | Details |
| A25437 | 21843565 | Arch Med Res | Treatment of atherogenic liver based on the pathogenesis of nonalcoholic fatty liver disease: a novel approach to reduce cardiovascular risk? | 2011 | Details |
| A25444 | 21835806 | J Gerontol A Biol Sci Med Sci | Aging is associated with a shift of fatty metabolism toward lipogenesis. | 2011 | Details |
| A25449 | 21821020 | Exp Mol Pathol | Liver mitochondrial function and redox status in an experimental model of non-alcoholic fatty liver disease induced by monosodium L-glutamate in rats. | 2011 | Details |
| A25453 | 21817060 | Am J Physiol Gastrointest Liver Physiol | Altered lipid metabolism in Hfe-knockout mice promotes severe NAFLD and early fibrosis. | 2011 | Details |
| A25466 | 21801491 | Redox Rep | Unbalanced oxidant-antioxidant status and its effects in pediatric diseases. | 2011 | Details |
| A25469 | 21799478 | Obesity (Silver Spring) | Intermittent hypoxia exacerbates metabolic effects of diet-induced obesity. | 2011 | Details |