Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin resistance7794 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A15141 | 29077210 | Hepatology | Hepatocyte DUSP14 maintains metabolic homeostasis and suppresses inflammation in the liver. | 2018 | Details |
| A15145 | 29074727 | Gut | Liver Reptin/RUVBL2 controls glucose and lipid metabolism with opposite actions on mTORC1 and mTORC2 signalling. | 2017 | Details |
| A15147 | 29074597 | Diabetes | S-Nitrosoglutathione Reductase Dysfunction Contributes to Obesity-Associated Hepatic Insulin Resistance via Regulating Autophagy. | 2017 | Details |
| A15150 | 29073130 | PLoS One | Non-alcoholic fatty liver disease and the development of nephrolithiasis: A cohort study. | 2017 | Details |
| A15151 | 29073114 | Proc Natl Acad Sci U S A | Pathogenesis of hypothyroidism-induced NAFLD is driven by intra- and extrahepatic mechanisms. | 2017 | Details |
| A15162 | 29066788 | Sci Rep | Periodontal pathogenic bacteria, Aggregatibacter actinomycetemcomitans affect non-alcoholic fatty liver disease by altering gut microbiota and glucose metabolism. | 2017 | Details |
| A15163 | 29066462 | Am J Physiol Endocrinol Metab | Genetic ablation of Cyp8b1 preserves host metabolic function by repressing steatohepatitis and altering gut microbiota composition. | 2017 | Details |
| A15167 | 29065507 | Nutrients | Fatty Acids Consumption: The Role Metabolic Aspects Involved in Obesity and Its Associated Disorders. | 2017 | Details |
| A15174 | 29063908 | Am J Gastroenterol | Adherence to Mediterranean Diet and Non-Alcoholic Fatty Liver Disease: Effect on Insulin Resistance. | 2017 | Details |
| A15195 | 29055928 | Ann Hepatol | New Onset Diabetes and Non-Alcoholic Fatty Liver Disease after Liver Transplantation. | 2018 | Details |
| A15197 | 29055919 | Ann Hepatol | The Expression of PNPLA3 Polymorphism could be the Key for Severe Liver Disease in NAFLD in Hispanic Population. | 2018 | Details |
| A15203 | 29051986 | Osteoporos Int | The relationship between fatty liver index and bone mineral density in Koreans: KNHANES 2010-2011. | 2017 | Details |
| A15204 | 29051770 | Nutr Metab (Lond) | Serum alanine aminotransferase/aspartate aminotransferase ratio is one of the best markers of insulin resistance in the Chinese population. | 2017 | Details |
| A15208 | 29049354 | PLoS One | Inverse association of marijuana use with nonalcoholic fatty liver disease among adults in the United States. | 2017 | Details |
| A15210 | 29046007 | Dtsch Med Wochenschr | [Dietary Recommendations in Metabolic Vascular Syndrome]. | 2017 | Details |
| A15223 | 29037210 | Lipids Health Dis | A vicious circle between insulin resistance and inflammation in nonalcoholic fatty liver disease. | 2017 | Details |
| A15228 | 29035308 | Nutrients | Gut Microbiota and Nonalcoholic Fatty Liver Disease: Insights on Mechanisms and Therapy. | 2017 | Details |
| A15229 | 29035092 | Crit Rev Food Sci Nutr | Vitamin D supplementation and non-alcoholic fatty liver disease: A critical and systematic review of clinical trials. | 2017 | Details |
| A15233 | 29031724 | Mol Metab | Elevated hepatic DPP4 activity promotes insulin resistance and non-alcoholic fatty liver disease. | 2017 | Details |
| A15237 | 29028831 | PLoS One | Short-term vitamin E treatment impairs reactive oxygen species signaling required for adipose tissue expansion, resulting in fatty liver and insulin resistance in obese mice. | 2017 | Details |
| A15241 | 29027424 | Zhongguo Zhong Yao Za Zhi | [Research progress on therapeutic targets of active components in Chinese herbs for treatment of nonalcoholic fatty liver disease]. | 2017 | Details |
| A15247 | 29024899 | Biomed Pharmacother | Mangiferin ameliorates fatty liver via modulation of autophagy and inflammation in high-fat-diet induced mice. | 2017 | Details |
| A15248 | 29024702 | Metabolism | Polycystic ovarian syndrome (PCOS): Long-term metabolic consequences. | 2017 | Details |
| A15253 | 29023387 | Nutrients | Combination of β-glucan and Morus alba L. Leaf Extract Promotes Metabolic Benefits in Mice Fed a High-Fat Diet. | 2017 | Details |
| A15269 | 28993156 | Diabetes Res Clin Pract | Association between hemoglobin glycation index and hepatic steatosis in non-diabetic individuals. | 2017 | Details |
| A15270 | 28993096 | Transl Res | Altered expression of MALAT1 lncRNA in nonalcoholic steatohepatitis fibrosis regulates CXCL5 in hepatic stellate cells. | 2017 | Details |
| A15272 | 28991837 | J Pediatr Gastroenterol Nutr | Serum Osteocalcin Levels in Children With Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A15274 | 28990251 | J Gastroenterol Hepatol | Waist-to-calf circumstance ratio is an independent predictor of hepatic steatosis and fibrosis in patients with type 2 diabetes. | 2018 | Details |
| A15284 | 28987323 | Pharmacol Ther | The longevity gene INDY (I'm Not Dead Yet) in metabolic control: Potential as pharmacological target. | 2017 | Details |
| A15285 | 28987260 | Clin Liver Dis | Treatment Strategies for Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis. | 2017 | Details |
| A15293 | 28982243 | J Agric Food Chem | Solanum nigrum Polyphenol Extracts Inhibit Hepatic Inflammation, Oxidative Stress, and Lipogenesis in High-Fat-Diet-Treated Mice. | 2017 | Details |
| A15295 | 28981167 | Acta Paediatr | Serum complement factor 5a levels are associated with nonalcoholic fatty liver disease in obese children. | 2017 | Details |
| A15297 | 28980219 | Curr Environ Health Rep | Persistent Endocrine-Disrupting Chemicals and Fatty Liver Disease. | 2017 | Details |
| A15300 | 28975492 | Obes Surg | Sleeve Gastrectomy Outcomes in Patients with BMI Between 30 and 35-3 Years of Follow-Up. | 2018 | Details |
| A15307 | 28972537 | J Clin Invest | Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling. | 2017 | Details |
| A15308 | 28972487 | Georgian Med News | EFFECT THE CARDIOMETABOLIC RISK FACTORS ON VASCULAR AGING IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE CONCOMITANT WITH SUBCLINICAL HYPOTHYROIDISM. | 2017 | Details |
| A15311 | 28971838 | Am J Physiol Gastrointest Liver Physiol | Hyperglucagonemia correlates with plasma levels of non-branched-chain amino acids in patients with liver disease independent of type 2 diabetes. | 2017 | Details |
| A15313 | 28970836 | Front Immunol | Fructose: A Dietary Sugar in Crosstalk with Microbiota Contributing to the Development and Progression of Non-Alcoholic Liver Disease. | 2017 | Details |
| A15329 | 28965028 | Diabetes Res Clin Pract | Angiopoietin-like protein 8: An attractive biomarker for the evaluation of subjects with insulin resistance and related disorders. | 2017 | Details |
| A15332 | 28964678 | Dig Liver Dis | Fat accumulates preferentially in the right rather than the left liver lobe in non-diabetic subjects. | 2017 | Details |
| A15340 | 28956824 | Nutrients | Translational Aspects of Diet and Non-Alcoholic Fatty Liver Disease. | 2017 | Details |
| A15341 | 28956816 | Nutrients | Qualitative and Quantitative Evaluation of Dietary Intake in Patients with Non-Alcoholic Steatohepatitis. | 2017 | Details |
| A15357 | 28948002 | Oncotarget | Linking atrial fibrillation with non-alcoholic fatty liver disease: potential common therapeutic targets. | 2017 | Details |
| A15363 | 28945101 | DNA Cell Biol | Implications of Sortilin in Lipid Metabolism and Lipid Disorder Diseases. | 2017 | Details |
| A15366 | 28942551 | J Endocrinol Invest | Androgen excess and metabolic disorders in women with PCOS: beyond the body mass index. | 2017 | Details |
| A15368 | 28942436 | Horm Mol Biol Clin Investig | The color of fat and its central role in the development and progression of metabolic diseases. | 2017 | Details |
| A15369 | 28942246 | Free Radic Biol Med | Inhibition of hepatocyte nuclear factor 1b induces hepatic steatosis through DPP4/NOX1-mediated regulation of superoxide. | 2017 | Details |
| A15372 | 28941597 | Metabolism | Immunomodulatory liposomes targeting liver macrophages arrest progression of nonalcoholic steatohepatitis. | 2017 | Details |
| A15374 | 28940752 | Mol Nutr Food Res | Supplementation with Docosahexaenoic Acid and Extra Virgin Olive Oil Prevents Liver Steatosis Induced by a High-Fat Diet in Mice through PPAR-α and Nrf2 Upregulation with Concomitant SREBP-1c and NF-kB Downregulation. | 2017 | Details |
| A15375 | 28940700 | Hepatology | Therapeutic inhibition of inflammatory monocyte recruitment reduces steatohepatitis and liver fibrosis. | 2018 | Details |
| A15378 | 28938455 | J Clin Endocrinol Metab | Bile Acid Alterations Are Associated With Insulin Resistance, but Not With NASH, in Obese Subjects. | 2017 | Details |
| A15383 | 28936403 | J Clin Transl Hepatol | Non-alcoholic Fatty Liver Disease in Lean Subjects: Characteristics and Implications. | 2017 | Details |
| A15393 | 28932090 | World J Gastroenterol | New botanical drug, HL tablet, reduces hepatic fat as measured by magnetic resonance spectroscopy in patients with nonalcoholic fatty liver disease: A placebo-controlled, randomized, phase II trial. | 2017 | Details |
| A15396 | 28931589 | J Nutr | Oral Supplementation of Glutamine Attenuates the Progression of Nonalcoholic Steatohepatitis in C57BL/6J Mice. | 2017 | Details |
| A15397 | 28931435 | Lipids Health Dis | Circulating retinol binding protein 4 levels in nonalcoholic fatty liver disease: a systematic review and meta-analysis. | 2017 | Details |
| A15403 | 28928235 | Am J Physiol Endocrinol Metab | Testosterone protects high-fat/low-carbohydrate diet-induced nonalcoholic fatty liver disease in castrated male rats mainly via modulating endoplasmic reticulum stress. | 2017 | Details |
| A15409 | 28925934 | J Clin Med | Can Diet Help Non-Obese Individuals with Non-Alcoholic Fatty Liver Disease (NAFLD)? | 2017 | Details |
| A15411 | 28925124 | Zhongguo Zhong Yao Za Zhi | [Effects of lotus leaf on inflammatory factors and liver AdipoR2 expressions in rats with NAFLD induced by high fat diet and high glucose]. | 2016 | Details |
| A15421 | 28922096 | J Am Coll Nutr | The Effects of Ramadan Fasting on Body Composition, Blood Pressure, Glucose Metabolism, and Markers of Inflammation in NAFLD Patients: An Observational Trial. | 2017 | Details |
| A15429 | 28918389 | J Investig Med | Glucagon like peptide-1 receptor agonists for the management of obesity and non-alcoholic fatty liver disease: a novel therapeutic option. | 2017 | Details |
| A15430 | 28918170 | Clin Nutr | Lifestyle predictors of obese and non-obese patients with nonalcoholic fatty liver disease: A cross-sectional study. | 2017 | Details |
| A15438 | 28906453 | Nutrients | Vitamin D Supplementation and Non-Alcoholic Fatty Liver Disease: Present and Future. | 2017 | Details |
| A15441 | 28905319 | J Physiol Biochem | PI3K inhibition protects mice from NAFLD by down-regulating CMKLR1 and NLRP3 in Kupffer cells. | 2017 | Details |
| A15443 | 28904866 | FEBS Open Bio | IMM-H007, a new therapeutic candidate for nonalcoholic fatty liver disease, improves hepatic steatosis in hamsters fed a high-fat diet. | 2017 | Details |
| A15444 | 28904022 | FASEB J | PI3Kγ ablation does not promote diabetes in db/db mice, but improves insulin sensitivity and reduces pancreatic β-cell apoptosis. | 2017 | Details |
| A15451 | 28900935 | Adv Exp Med Biol | Metabolic Disorders and Cancer: Hepatocyte Store-Operated Ca2+ Channels in Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A15454 | 28899857 | Am J Physiol Endocrinol Metab | High-fat, high-fructose, high-cholesterol feeding causes severe NASH and cecal microbiota dysbiosis in juvenile Ossabaw swine. | 2017 | Details |
| A15456 | 28899715 | J Steroid Biochem Mol Biol | The relationship between 25-hydroxyvitamin D concentration and liver enzymes in overweight or obese adults: Cross-sectional and interventional outcomes. | 2017 | Details |
| A15457 | 28898507 | Liver Int | Growth differentiation factor 15 predicts advanced fibrosis in biopsy-proven non-alcoholic fatty liver disease. | 2017 | Details |
| A15459 | 28895929 | Nutrients | Effects of Oral Administration of Silymarin in a Juvenile Murine Model of Non-alcoholic Steatohepatitis. | 2017 | Details |
| A15466 | 28894050 | Postepy Hig Med Dosw (Online) | Compounds of psoriasis with obesity and overweight. | 2017 | Details |
| A15467 | 28892924 | J Clin Diagn Res | Comparison of Pioglitazone and Metformin Efficacy against Glucocorticoid Induced Atherosclerosis and Hepatic Steatosis in Insulin Resistant Rats. | 2017 | Details |
| A15470 | 28892211 | Pediatr Int | Early menarche is associated with non-alcoholic fatty liver disease in adulthood. | 2017 | Details |
| A15471 | 28892095 | Lab Invest | Cholecystectomy as a risk factor of metabolic syndrome: from epidemiologic clues to biochemical mechanisms. | 2017 | Details |
| A15476 | 28886991 | J Diabetes Complications | Molecular mechanisms of nonalcoholic fatty liver disease: Potential role for 12-lipoxygenase. | 2017 | Details |
| A15478 | 28883965 | Trop Dis Travel Med Vaccines | Hepatic steatosis in HCV-infected persons in the direct-acting antiviral era. | 2016 | Details |
| A15479 | 28883861 | Arch Med Sci | Bioavailable testosterone is independently associated with Fatty Liver Index in postmenopausal women. | 2017 | Details |
| A15480 | 28883393 | Nat Commun | Fas cell surface death receptor controls hepatic lipid metabolism by regulating mitochondrial function. | 2017 | Details |
| A15483 | 28880885 | PLoS One | Markers of intestinal permeability are already altered in early stages of non-alcoholic fatty liver disease: Studies in children. | 2017 | Details |
| A15485 | 28880231 | Nutrients | The Impact of Sex and 25(OH)D Deficiency on Metabolic Function in Mice. | 2017 | Details |
| A15489 | 28878197 | Nutrients | Fructose Consumption, Lipogenesis, and Non-Alcoholic Fatty Liver Disease. | 2017 | Details |
| A15490 | 28878132 | JCI Insight | Therapeutic opportunities for alcoholic steatohepatitis and nonalcoholic steatohepatitis: exploiting similarities and differences in pathogenesis. | 2017 | Details |
| A15496 | 28875689 | Minerva Gastroenterol Dietol | Liver fibrosis in the context of nonalcoholic steatohepatitis: the role of adipokines. | 2017 | Details |
| A15501 | 28874313 | Gastroenterol Hepatol | New therapeutic perspectives in non-alcoholic steatohepatitis. | 2017 | Details |
| A15507 | 28869588 | Lab Invest | Activation of pluripotent genes in hepatic progenitor cells in the transition of nonalcoholic steatohepatitis to pre-malignant lesions. | 2017 | Details |
| A15508 | 28869506 | Int J Mol Sci | Critical Role of the Human ATP-Binding Cassette G1 Transporter in Cardiometabolic Diseases. | 2017 | Details |
| A15511 | 28868179 | World J Gastrointest Pathophysiol | Fatty liver without a large "belly": Magnified review of non-alcoholic fatty liver disease in non-obese patients. | 2017 | Details |
| A15512 | 28868048 | Front Endocrinol (Lausanne) | Extracellular Vesicles from Adipose Tissue-A Potential Role in Obesity and Type 2 Diabetes? | 2017 | Details |
| A15513 | 28867301 | Cell Metab | Nonalcoholic Fatty Liver Disease as a Nexus of Metabolic and Hepatic Diseases. | 2017 | Details |
| A15524 | 28862329 | J Sci Food Agric | Virgin coconut oil reverses hepatic steatosis by restoring redox homeostasis and lipid metabolism in male Wistar rats. | 2017 | Details |
| A15528 | 28859855 | Gastroenterology | Degradation of PHLPP2 by KCTD17, via a Glucagon-Dependent Pathway, Promotes Hepatic Steatosis. | 2017 | Details |
| A15547 | 28848738 | Front Cardiovasc Med | Vascular Endothelial Regulation of Obesity-Associated Insulin Resistance. | 2017 | Details |
| A15573 | 28838784 | Clin Gastroenterol Hepatol | Noninvasive Tests Do Not Accurately Differentiate Nonalcoholic Steatohepatitis From Simple Steatosis: A Systematic Review and Meta-analysis. | 2017 | Details |
| A15577 | 28836404 | Cell J | Anti-Inflammatory Effects of Curcumin on Insulin Resistance Index, Levels of Interleukin-6, C-Reactive Protein, and Liver Histology in Polycystic Ovary Syndrome-Induced Rats. | 2017 | Details |
| A15582 | 28831172 | Sci Rep | Pioglitazone Enhances Cytosolic Lipolysis, β-oxidation and Autophagy to Ameliorate Hepatic Steatosis. | 2017 | Details |
| A15585 | 28828531 | Abdom Radiol (NY) | Quantitative MRI of fatty liver disease in a large pediatric cohort: correlation between liver fat fraction, stiffness, volume, and patient-specific factors. | 2018 | Details |
| A15588 | 28825992 | J Nutr Biochem | Effects of delta-tocotrienol on obesity-related adipocyte hypertrophy, inflammation and hepatic steatosis in high-fat-fed mice. | 2017 | Details |
| A15600 | 28820447 | Int J Mol Sci | Comprehensive Study of Multiple Stages Progressing to Nonalcoholic Steatohepatitis with Subsequent Fibrosis in SD Rats. | 2017 | Details |
| A15601 | 28820393 | J Physiol Pharmacol | Fibroblast growth factor-21 and omentin-1 hepatic mRNA expression and serum levels in morbidly obese women with non-alcoholic fatty liver disease. | 2017 | Details |
| A15607 | 28814531 | J Nutr | Patients with Nonalcoholic Fatty Liver Disease Have a Low Response Rate to Vitamin D Supplementation. | 2017 | Details |