Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A16645 | 28267621 | J Hepatol | Targeting hepatic macrophages to treat liver diseases. | 2017 | Details |
| A16650 | 28265826 | Dig Dis Sci | Intestinal Inflammation Does Not Predict Nonalcoholic Fatty Liver Disease Severity in Inflammatory Bowel Disease Patients. | 2017 | Details |
| A16652 | 28264426 | Nutrients | The Combination of Blueberry Juice and Probiotics Ameliorate Non-Alcoholic Steatohepatitis (NASH) by Affecting SREBP-1c/PNPLA-3 Pathway via PPAR-α. | 2017 | Details |
| A16657 | 28260907 | Ther Clin Risk Manag | Effect of orlistat on periostin, adiponectin, inflammatory markers and ultrasound grades of fatty liver in obese NAFLD patients. | 2017 | Details |
| A16660 | 28258704 | Hepatol Res | Non-alcoholic fatty liver disease phosphoproteomics: A functional piece of the precision puzzle. | 2017 | Details |
| A16663 | 28257515 | PLoS One | New evidence for the therapeutic potential of curcumin to treat nonalcoholic fatty liver disease in humans. | 2017 | Details |
| A16681 | 28249273 | Dig Dis | Intestinal Farnesoid X Receptor and Takeda G Protein Couple Receptor 5 Signaling in Metabolic Regulation. | 2017 | Details |
| A16682 | 28249257 | Dig Dis | Therapeutic Mechanisms of Bile Acids and Nor-Ursodeoxycholic Acid in Non-Alcoholic Fatty Liver Disease. | 2017 | Details |
| A16683 | 28249038 | PLoS One | Microvesicles released from fat-laden cells promote activation of hepatocellular NLRP3 inflammasome: A pro-inflammatory link between lipotoxicity and non-alcoholic steatohepatitis. | 2017 | Details |
| A16684 | 28245087 | Hepatol Res | Hepatic nucleotide binding oligomerization domain-like receptors pyrin domain-containing 3 inflammasomes are associated with the histologic severity of non-alcoholic fatty liver disease. | 2017 | Details |
| A16687 | 28244120 | Hepatology | The histone methyltransferase Suv39h2 contributes to nonalcoholic steatohepatitis in mice. | 2017 | Details |
| A16691 | 28241817 | BMC Endocr Disord | Berberine improves glucogenesis and lipid metabolism in nonalcoholic fatty liver disease. | 2017 | Details |
| A16709 | 28231052 | Acta Pharm | Review. The role of peroxisome proliferator-activated receptor in the treatment of non-alcoholic fatty liver disease. | 2017 | Details |
| A16711 | 28230324 | Diabetes Obes Metab | Effects of short-term energy restriction on liver lipid content and inflammatory status in severely obese adults: Results of a randomized controlled trial using 2 dietary approaches. | 2017 | Details |
| A16720 | 28223710 | Sci Rep | High-Intensity Aerobic Exercise Improves Both Hepatic Fat Content and Stiffness in Sedentary Obese Men with Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A16724 | 28222828 | Nutr Res Rev | Metabolic consequences of obesity and insulin resistance in polycystic ovary syndrome: diagnostic and methodological challenges. | 2017 | Details |
| A16727 | 28220495 | J Pharm Pharmacol | Influence of hyperglycemia on liver inflammatory conditions in the early phase of non-alcoholic fatty liver disease in mice. | 2017 | Details |
| A16733 | 28218263 | Nat Rev Nephrol | Non-alcoholic fatty liver disease: an emerging driving force in chronic kidney disease. | 2017 | Details |
| A16751 | 28210913 | Int Urol Nephrol | Dietary and commercialized fructose: Sweet or sour? | 2017 | Details |
| A16752 | 28209760 | Diabetes | Glucoraphanin Ameliorates Obesity and Insulin Resistance Through Adipose Tissue Browning and Reduction of Metabolic Endotoxemia in Mice. | 2017 | Details |
| A16755 | 28206970 | Oncotarget | Genetic variation in long noncoding RNAs and the risk of nonalcoholic fatty liver disease. | 2017 | Details |
| A16758 | 28202906 | Sci Rep | BAR502, a dual FXR and GPBAR1 agonist, promotes browning of white adipose tissue and reverses liver steatosis and fibrosis. | 2017 | Details |
| A16766 | 28194019 | Cell Mol Immunol | IL-25 stimulates M2 macrophage polarization and thereby promotes mitochondrial respiratory capacity and lipolysis in adipose tissues against obesity. | 2017 | Details |
| A16768 | 28192190 | J Hepatol | β7-Integrin and MAdCAM-1 play opposing roles during the development of non-alcoholic steatohepatitis. | 2017 | Details |
| A16772 | 28189916 | J Nutr Biochem | Chronic administration of saturated fats and fructose differently affect SREBP activity resulting in different modulation of Nrf2 and Nlrp3 inflammasome pathways in mice liver. | 2017 | Details |
| A16774 | 28185715 | Clin Ther | Effects of Oral Antidiabetic Drugs on Changes in the Liver-to-Spleen Ratio on Computed Tomography and Inflammatory Biomarkers in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A16785 | 28178440 | Rambam Maimonides Med J | Comorbidities in Patients with Psoriatic Arthritis. | 2017 | Details |
| A16786 | 28177750 | Appl Physiol Nutr Metab | Modulatory role of Co-enzyme Q10 on methionine and choline deficient diet-induced non-alcoholic steatohepatitis (NASH) in albino rats. | 2016 | Details |
| A16792 | 28174796 | Rom J Morphol Embryol | Non-alcoholic fatty liver disease - clinical and histopathological aspects. | 2016 | Details |
| A16795 | 28169366 | Sci Rep | Phytosterol esters attenuate hepatic steatosis in rats with non-alcoholic fatty liver disease rats fed a high-fat diet. | 2017 | Details |
| A16796 | 28167864 | J Inflamm (Lond) | Ezetimibe reduces cholesterol content and NF-kappaB activation in liver but not in intestinal tissue in guinea pigs. | 2017 | Details |
| A16798 | 28167322 | J Hepatol | NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice. | 2017 | Details |
| A16803 | 28164196 | Food Funct | Preventive effect of Silibinin in combination with Pu-erh tea extract on non-alcoholic fatty liver disease in ob/ob mice. | 2017 | Details |
| A16804 | 28163820 | Oxid Med Cell Longev | Apolipoprotein CIII Overexpression-Induced Hypertriglyceridemia Increases Nonalcoholic Fatty Liver Disease in Association with Inflammation and Cell Death. | 2017 | Details |
| A16810 | 28160250 | Curr Treat Options Gastroenterol | Thiopurines and Methotrexate Use in IBD Patients in a Biologic Era. | 2017 | Details |
| A16813 | 28158893 | Drug Res (Stuttg) | Efficacy and Safety of Phytosomal Curcumin in Non-Alcoholic Fatty Liver Disease: A Randomized Controlled Trial. | 2017 | Details |
| A16815 | 28157387 | Can J Physiol Pharmacol | Trigonelline attenuates hepatic complications and molecular alterations in high-fat high-fructose diet-induced insulin resistance in rats. | 2016 | Details |
| A16817 | 28155087 | Curr Gastroenterol Rep | The Association Between Helicobacter pylori Infection and Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A16818 | 28154266 | Intern Med | The Serum Oxidative/Anti-oxidative Stress Balance Becomes Dysregulated in Patients with Non-alcoholic Steatohepatitis Associated with Hepatocellular Carcinoma. | 2017 | Details |
| A16825 | 28146130 | Nutrients | Effects of Natural Products on Fructose-Induced Nonalcoholic Fatty Liver Disease (NAFLD). | 2017 | Details |
| A16829 | 28143996 | Acta Med Indones | The Role of Probiotic in Reducing Hepatic Inflammation Among NAFLD Patients: an Evidence-based Case Report. | 2016 | Details |
| A16833 | 28139281 | Clin Nutr | Non-alcoholic fatty liver disease and its treatment with n-3 polyunsaturated fatty acids. | 2017 | Details |
| A16834 | 28139128 | Vnitr Lek | [Coffee as hepatoprotective factor]. | 2017 | Details |
| A16835 | 28138308 | Int J Med Sci | Steatosis influences the clinical profiles and long-term outcomes of interferon-treated chronic hepatitis C and liver cirrhosis patients. | 2017 | Details |
| A16838 | 28134687 | Curr Opin Gastroenterol | Fecal microbiota transplantation for gastrointestinal disorders. | 2017 | Details |
| A16843 | 28132721 | Immunobiology | Hepatic interleukin-6 production is maintained during endotoxin tolerance and facilitates lipid accumulation. | 2017 | Details |
| A16849 | 28127545 | Can J Gastroenterol Hepatol | Advanced Hepatic Fibrosis in Fatty Liver Disease Linked to Hyperplastic Colonic Polyp. | 2017 | Details |
| A16856 | 28125040 | Molecules | Silymarin/Silybin and Chronic Liver Disease: A Marriage of Many Years. | 2017 | Details |
| A16861 | 28123944 | Mol Metab | Celastrol ameliorates liver metabolic damage caused by a high-fat diet through Sirt1. | 2016 | Details |
| A16866 | 28120721 | Curr Pharm Des | Progranulin, a New Adipokine at the Crossroads of Metabolic Syndrome, Diabetes, Dyslipidemia and Hypertension. | 2017 | Details |
| A16867 | 28120165 | J Inherit Metab Dis | Investigating the link of ACAD10 deficiency to type 2 diabetes mellitus. | 2017 | Details |
| A16868 | 28119530 | Int J Obes (Lond) | Decreased lipid metabolism but increased FA biosynthesis are coupled with changes in liver microRNAs in obese subjects with NAFLD. | 2017 | Details |
| A16872 | 28116779 | Mol Nutr Food Res | Long-term dietary supplementation with low-dose nobiletin ameliorates hepatic steatosis, insulin resistance, and inflammation without altering fat mass in diet-induced obesity. | 2017 | Details |
| A16874 | 28115925 | PPAR Res | PPARs and Mitochondrial Metabolism: From NAFLD to HCC. | 2016 | Details |
| A16875 | 28115795 | Mediators Inflamm | The Role of Tissue Macrophage-Mediated Inflammation on NAFLD Pathogenesis and Its Clinical Implications. | 2017 | Details |
| A16876 | 28115523 | J Biol Chem | APOC3 Protein Is Not a Predisposing Factor for Fat-induced Nonalcoholic Fatty Liver Disease in Mice. | 2017 | Details |
| A16886 | 28110193 | Biomed Pharmacother | Effects of polyphenol compounds melanin on NAFLD/NASH prevention. | 2017 | Details |
| A16887 | 28110063 | Int Immunopharmacol | Curcumin ameliorates liver damage and progression of NASH in NASH-HCC mouse model possibly by modulating HMGB1-NF-κB translocation. | 2017 | Details |
| A16890 | 28109099 | Nan Fang Yi Ke Da Xue Xue Bao | [Effect of Hugan Qingzhi tablets on AMPK pathway activation and NF-κB-p65 protein expression in the liver of rats with nonalcoholic fatty liver disease]. | 2017 | Details |
| A16892 | 28108233 | J Hepatol | Murine CD103+ dendritic cells protect against steatosis progression towards steatohepatitis. | 2017 | Details |
| A16894 | 28107471 | PLoS One | High Serum Lipopolysaccharide-Binding Protein Level in Chronic Hepatitis C Viral Infection Is Reduced by Anti-Viral Treatments. | 2017 | Details |
| A16906 | 28100771 | J Biol Chem | Janus Kinase 2 (JAK2) Dissociates Hepatosteatosis from Hepatocellular Carcinoma in Mice. | 2017 | Details |
| A16908 | 28099601 | An Bras Dermatol | Psoriasis comorbidities: complications and benefits of immunobiological treatment. | 2017 | Details |
| A16919 | 28092182 | Exp Biol Med (Maywood) | An estrogen receptor β-selective agonist inhibits non-alcoholic steatohepatitis in preclinical models by regulating bile acid and xenobiotic receptors. | 2017 | Details |
| A16923 | 28090564 | Cell Mol Gastroenterol Hepatol | Hepatocyte Toll-Like Receptor 5 Promotes Bacterial Clearance and Protects Mice Against High-Fat Diet-Induced Liver Disease. | 2016 | Details |
| A16933 | 28086768 | BMC Complement Altern Med | Probiotic mixture improves fatty liver disease by virtue of its action on lipid profiles, leptin, and inflammatory biomarkers. | 2017 | Details |
| A16935 | 28084795 | Appl Physiol Nutr Metab | Moderate physical activity promotes basal hepatic autophagy in diet-induced obese mice. | 2016 | Details |
| A16940 | 28082742 | Exp Mol Med | Gene-metabolite network analysis in different nonalcoholic fatty liver disease phenotypes. | 2017 | Details |
| A16947 | 28078997 | Curr Med Chem | Lipoprotein (a) and Cardiovascular Risk: The Show Must go on. | 2017 | Details |
| A16950 | 28077318 | Exp Mol Pathol | Alcohol, microbiome, life style influence alcohol and non-alcoholic organ damage. | 2017 | Details |
| A16953 | 28076416 | PLoS One | The CCR2 Inhibitor Propagermanium Attenuates Diet-Induced Insulin Resistance, Adipose Tissue Inflammation and Non-Alcoholic Steatohepatitis. | 2017 | Details |
| A16960 | 28073424 | Zhonghua Gan Zang Bing Za Zhi | [NACHT-LRR-PYD-containing proteins 3 inflammasome and nonalcoholic fatty liver disease]. | 2016 | Details |
| A16962 | 28073414 | Zhonghua Gan Zang Bing Za Zhi | [Protective effect of Saccharomyces boulardii against intestinal mucosal barrier injury in rats with nonalcoholic fatty liver disease]. | 2016 | Details |
| A16981 | 28064013 | J Nutr Biochem | Changes in liver proteins of rats fed standard and high-fat and sucrose diets induced by fish omega-3 PUFAs and their combination with grape polyphenols according to quantitative proteomics. | 2016 | Details |
| A16986 | 28063004 | Mol Cell Biochem | Tubulin alpha 8 is expressed in hepatic stellate cells and is induced in transformed hepatocytes. | 2017 | Details |
| A17008 | 28051796 | Ann Hepatol |  Differences in hepatic expression of iron, inflammation and stress-related genes in patients with nonalcoholic steatohepatitis. | 2017 | Details |
| A17009 | 28051792 | Ann Hepatol | Management strategies for liver fibrosis. | 2017 | Details |
| A17011 | 28051126 | Sci Rep | Cytochrome P450-2E1 promotes fast food-mediated hepatic fibrosis. | 2017 | Details |
| A17015 | 28044208 | J Gastroenterol | Hepatic vagus nerve regulates Kupffer cell activation via α7 nicotinic acetylcholine receptor in nonalcoholic steatohepatitis. | 2017 | Details |
| A17018 | 28042486 | Int J Hepatol | A Combination of Leucine, Metformin, and Sildenafil Treats Nonalcoholic Fatty Liver Disease and Steatohepatitis in Mice. | 2016 | Details |
| A17022 | 28039158 | Am J Physiol Gastrointest Liver Physiol | Inhibition of sphingosine 1-phosphate signaling ameliorates murine nonalcoholic steatohepatitis. | 2016 | Details |
| A17032 | 29911800 | Yao Xue Xue Bao | [Protective effect and underlying mechanism of cordycepin on non-alcoholic fatty liver in ob/ob mice]. | 2017 | Details |
| A17037 | 28038359 | J Nutr Biochem | Green tea extract treatment reduces NFκB activation in mice with diet-induced nonalcoholic steatohepatitis by lowering TNFR1 and TLR4 expression and ligand availability. | 2016 | Details |
| A17061 | 28013023 | Semin Cell Dev Biol | Metabolic roles of poly(ADP-ribose) polymerases. | 2016 | Details |
| A17062 | 28012599 | Med Hypotheses | Blood oxidative stress (BLOS) is a secondary host defense system responding normally to anaerobic wound infection and inadvertently to dietary ultra-exogenous sulfide formation (USF). | 2016 | Details |
| A17067 | 28011892 | Gut | Adipose type I interferon signalling protects against metabolic dysfunction. | 2016 | Details |
| A17069 | 28011152 | Transl Res | Adenosine A2a receptor stimulation blocks development of nonalcoholic steatohepatitis in mice by multilevel inhibition of signals that cause immunolipotoxicity. | 2016 | Details |
| A17073 | 28007783 | FASEB J | Early PQQ supplementation has persistent long-term protective effects on developmental programming of hepatic lipotoxicity and inflammation in obese mice. | 2016 | Details |
| A17074 | 28007354 | Sleep Med | Gut epithelial barrier markers in patients with obstructive sleep apnea. | 2016 | Details |
| A17085 | 27999564 | Front Endocrinol (Lausanne) | Distinct Hepatic Macrophage Populations in Lean and Obese Mice. | 2016 | Details |
| A17087 | 27998724 | Am J Pathol | Global Deletion of Glutathione S-Transferase A4 Exacerbates Developmental Nonalcoholic Steatohepatitis. | 2016 | Details |
| A17096 | 27995280 | Arch Toxicol | Dietary fructose as a risk factor for non-alcoholic fatty liver disease (NAFLD). | 2016 | Details |
| A17099 | 27992443 | PLoS One | Pro-Inflammatory Cytokines but Not Endotoxin-Related Parameters Associate with Disease Severity in Patients with NAFLD. | 2016 | Details |
| A17114 | 27984800 | Biomed Pharmacother | Saponins from the roots of Platycodon grandiflorum ameliorate high fat diet-induced non-alcoholic steatohepatitis. | 2016 | Details |
| A17116 | 27984176 | J Hepatol | PARP inhibition protects against alcoholic and non-alcoholic steatohepatitis. | 2016 | Details |
| A17118 | 27982256 | Acta Cir Bras | Effect of curcumin on visfatin and zinc-α2-glycoprotein in a rat model of non-alcoholic fatty liver disease. | 2016 | Details |
| A17120 | 27981809 | Mol Nutr Food Res | Chicoric acid attenuate a nonalcoholic steatohepatitis by inhibiting key regulators of lipid metabolism, fibrosis, oxidation, and inflammation in mice with methionine and choline deficiency. | 2017 | Details |
| A17126 | 27978932 | Zhonghua Gan Zang Bing Za Zhi | [Preventive and therapeutic effects of compound ginkgo extract in rats with nonalcoholic steatohepatitis induced by high-fat, high-fructose diet]. | 2016 | Details |
| A17137 | 27967209 | Antioxid Redox Signal | Cluster of Differentiation 36 Deficiency Aggravates Macrophage Infiltration and Hepatic Inflammation by Upregulating Monocyte Chemotactic Protein-1 Expression of Hepatocytes Through Histone Deacetylase 2-Dependent Pathway. | 2017 | Details |
| A17143 | 27959936 | PLoS One | A Low Dose of Dietary Quercetin Fails to Protect against the Development of an Obese Phenotype in Mice. | 2016 | Details |