Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin resistance7794 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A16103 | 28570615 | PLoS One | Liver biopsy in type 2 diabetes mellitus: Steatohepatitis represents the sole feature of liver damage. | 2017 | Details |
| A16106 | 28567448 | Sci Immunol | Type I Interferon Responses Drive Intrahepatic T cells to Promote Metabolic Syndrome. | 2017 | Details |
| A16107 | 28566439 | Eur J Endocrinol | MECHANISMS IN ENDOCRINOLOGY: The sexually dimorphic role of androgens in human metabolic disease. | 2017 | Details |
| A16108 | 28566408 | J Mol Endocrinol | 5-ALA ameliorates hepatic steatosis through AMPK signaling pathway. | 2017 | Details |
| A16111 | 28562560 | Medicine (Baltimore) | Triglyceride glucose-body mass index is effective in identifying nonalcoholic fatty liver disease in nonobese subjects. | 2017 | Details |
| A16116 | 28558676 | BMC Endocr Disord | Association of calf circumference with insulin resistance and non-alcohol fatty liver disease: the REACTION study. | 2017 | Details |
| A16118 | 28555633 | Am J Gastroenterol | Low Birthweight Increases the Likelihood of Severe Steatosis in Pediatric Non-Alcoholic Fatty Liver Disease. | 2017 | Details |
| A16120 | 28554682 | Clin Gastroenterol Hepatol | Liver and Cardiovascular Damage in Patients With Lean Nonalcoholic Fatty Liver Disease, and Association With Visceral Obesity. | 2017 | Details |
| A16122 | 28551355 | Trends Pharmacol Sci | Roles of Diacylglycerols and Ceramides in Hepatic Insulin Resistance. | 2017 | Details |
| A16124 | 28550439 | Obes Surg | Baseline Anthropometric and Metabolic Parameters Correlate with Weight Loss in Women 1-Year After Laparoscopic Roux-En-Y Gastric Bypass. | 2017 | Details |
| A16126 | 28550272 | J Biomed Res | Non-alcoholic fatty liver disease--a chronic disease of the 21<sup>st</sup> century. | 2018 | Details |
| A16127 | 28549912 | Exp Cell Res | Fatty liver and FGF21 physiology. | 2017 | Details |
| A16143 | 28540988 | Yonsei Med J | Pathologic Impact of Insulin Resistance and Sensitivity on the Severity of Liver Histopathology in Pediatric Non-Alcoholic Steatohepatitis. | 2017 | Details |
| A16144 | 28540984 | Yonsei Med J | Inverse Relationship between Hepatic Steatosis and Alanine Aminotransferase with Sex Hormone-Binding Globulin in Men. | 2017 | Details |
| A16145 | 28539915 | Front Microbiol | The Possible Role of Helicobacter pylori Infection in Non-alcoholic Fatty Liver Disease. | 2017 | Details |
| A16152 | 28536120 | FASEB J | Hepatocyte-specific sirtuin 6 deletion predisposes to nonalcoholic steatohepatitis by up-regulation of Bach1, an Nrf2 repressor. | 2017 | Details |
| A16154 | 28534852 | Nutrients | Effects of Ketogenic Diets on Cardiovascular Risk Factors: Evidence from Animal and Human Studies. | 2017 | Details |
| A16164 | 28529199 | J Clin Res Pediatr Endocrinol | Can Fetuin-A Be a Marker for Insulin Resistance and Poor Glycemic Control in Children with Type 1 Diabetes Mellitus? | 2017 | Details |
| A16166 | 28527877 | Pharmacol Rep | Esculetin ameliorates hepatic fibrosis in high fat diet induced non-alcoholic fatty liver disease by regulation of FoxO1 mediated pathway. | 2017 | Details |
| A16167 | 28527304 | Diabetes Res Clin Pract | Additive effect of non-alcoholic fatty liver disease on the development of diabetes in individuals with metabolic syndrome. | 2017 | Details |
| A16177 | 28521680 | Curr Med Chem | Fatty Acids and Effects on In Vitro and In Vivo Models of Liver Steatosis. | 2019 | Details |
| A16180 | 28515456 | Sci Rep | Metabolomic analysis shows differential hepatic effects of T2 and T3 in rats after short-term feeding with high fat diet. | 2017 | Details |
| A16186 | 28511733 | Nutr Res Rev | Similarities and interactions between the ageing process and high chronic intake of added sugars. | 2017 | Details |
| A16191 | 28511161 | Wiad Lek | [The diagnostics and clinical pattern of nonalcoholic fatty liver disease in patients with pre-diabetes and type 2 diabetes and obesity]. | 2017 | Details |
| A16197 | 28508477 | Hepatology | The novel intracellular protein CREG inhibits hepatic steatosis, obesity, and insulin resistance. | 2017 | Details |
| A16198 | 28508194 | Endocrine | Fatty liver as a risk factor for progression from metabolically healthy to metabolically abnormal in non-overweight individuals. | 2017 | Details |
| A16202 | 28507837 | Cureus | Non-Alcoholic Fatty Liver Disease Association with Cardiac Arrhythmias. | 2017 | Details |
| A16204 | 28507343 | Sci Rep | Non-alcoholic fatty liver disease, vascular inflammation and insulin resistance are exacerbated by TRAIL deletion in mice. | 2017 | Details |
| A16216 | 28503750 | Diabetes Obes Metab | Comparative effects of liraglutide 3 mg vs structured lifestyle modification on body weight, liver fat and liver function in obese patients with non-alcoholic fatty liver disease: A pilot randomized trial. | 2017 | Details |
| A16237 | 28492501 | Nutrients | Urinary Metabolomics in Pediatric Obesity and NAFLD Identifies Metabolic Pathways/Metabolites Related to Dietary Habits and Gut-Liver Axis Perturbations. | 2017 | Details |
| A16238 | 28490707 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | [Effect of NF-κB on the pathogenic course of non-alcoholic fatty liver disease]. | 2017 | Details |
| A16239 | 28490610 | Diabetes | Mechanisms of Insulin Resistance in Primary and Secondary Nonalcoholic Fatty Liver. | 2017 | Details |
| A16241 | 28489136 | Rev Assoc Med Bras (1992) | Hyperferritinemia in patients with nonalcoholic fatty liver disease. | 2017 | Details |
| A16244 | 28487551 | Int J Obes (Lond) | High-free androgen index is associated with increased risk of non-alcoholic fatty liver disease in women with polycystic ovary syndrome, independent of obesity and insulin resistance. | 2017 | Details |
| A16245 | 28486193 | Biomed Pharmacother | Wogonin mitigates nonalcoholic fatty liver disease via enhancing PPARα/AdipoR2, in vivo and in vitro. | 2017 | Details |
| A16247 | 28484247 | Sci Rep | Total fecal microbiota transplantation alleviates high-fat diet-induced steatohepatitis in mice via beneficial regulation of gut microbiota. | 2017 | Details |
| A16253 | 28483554 | Biochim Biophys Acta Mol Cell Biol Lipids | Downregulation of miR-192 causes hepatic steatosis and lipid accumulation by inducing SREBF1: Novel mechanism for bisphenol A-triggered non-alcoholic fatty liver disease. | 2017 | Details |
| A16259 | 28481357 | Nat Med | Tmbim1 is a multivesicular body regulator that protects against non-alcoholic fatty liver disease in mice and monkeys by targeting the lysosomal degradation of Tlr4. | 2017 | Details |
| A16268 | 28476236 | Endocrinol Metab Clin North Am | Genetics of Lipodystrophy. | 2017 | Details |
| A16269 | 28475150 | Int J Mol Sci | Reply to the Letter to the Editor by Li et al.: Bioinformatics Analysis in Mice with Diet-Induced Nonalcoholic Steatohepatitis Treated with Astaxanthin and Vitamin E. | 2017 | Details |
| A16280 | 28471945 | AIDS | Metabolic concerns in aging HIV-infected persons: from serum lipid phenotype to fatty liver. | 2017 | Details |
| A16283 | 28471823 | Eur J Gastroenterol Hepatol | The effects of diet and lifestyle interventions on insulin resistance in patients with nonalcoholic fatty liver disease: a systematic review. | 2017 | Details |
| A16300 | 28468951 | Clin Sci (Lond) | Insulin resistance promotes Lysyl Oxidase Like 2 induction and fibrosis accumulation in non-alcoholic fatty liver disease. | 2017 | Details |
| A16301 | 28468933 | J Endocrinol | The metabolic syndrome in mice overexpressing neuropeptide Y in noradrenergic neurons. | 2017 | Details |
| A16315 | 28463404 | Mol Nutr Food Res | A synbiotic composed of Lactobacillus fermentum CECT5716 and FOS prevents the development of fatty acid liver and glycemic alterations in rats fed a high fructose diet associated with changes in the microbiota. | 2017 | Details |
| A16316 | 28462811 | Trends Endocrinol Metab | Sphingolipids and Lipoproteins in Health and Metabolic Disorders. | 2017 | Details |
| A16319 | 28461774 | Korean J Physiol Pharmacol | Endogenous catalase delays high-fat diet-induced liver injury in mice. | 2017 | Details |
| A16320 | 28461687 | Int J Obes (Lond) | Serum vascular cell adhesion molecule-1 predicts significant liver fibrosis in non-alcoholic fatty liver disease. | 2017 | Details |
| A16321 | 28460349 | Cancer Epidemiol | Nonalcoholic fatty liver disease and mortality among cancer survivors. | 2017 | Details |
| A16324 | 28458689 | Int J Endocrinol | Nonalcoholic Fatty Liver Disease and Associated Metabolic Risks of Hypertension in Type 2 Diabetes: A Cross-Sectional Community-Based Study. | 2017 | Details |
| A16336 | 28452101 | Diabetes Obes Metab | Effects of combined low-dose spironolactone plus vitamin E vs vitamin E monotherapy on insulin resistance, non-invasive indices of steatosis and fibrosis, and adipokine levels in non-alcoholic fatty liver disease: a randomized controlled trial. | 2017 | Details |
| A16342 | 28446519 | Diabetes | Cationic Polystyrene Resolves Nonalcoholic Steatohepatitis, Obesity, and Metabolic Disorders by Promoting Eubiosis of Gut Microbiota and Decreasing Endotoxemia. | 2017 | Details |
| A16345 | 28445310 | Medicine (Baltimore) | Diagnostic accuracy of serum alanine aminotransferase as biomarker for nonalcoholic fatty liver disease and insulin resistance in healthy subjects, using 3T MR spectroscopy. | 2017 | Details |
| A16348 | 28443804 | J Am Coll Nutr | 25(OH)D Levels in Relation to Gender, Overweight, Insulin Resistance, and Inflammation in a Cross-Sectional Cohort of Northern Italian Workers: Evidence in Support of Preventive Health Care Programs. | 2017 | Details |
| A16349 | 28443702 | J Am Coll Nutr | Turmeric Supplementation Improves Serum Glucose Indices and Leptin Levels in Patients with Nonalcoholic Fatty Liver Diseases. | 2017 | Details |
| A16364 | 28436456 | Sci Rep | Synthesis and anti-obesity effects in vivo of Crotadihydrofuran C as a novel PPARγ antagonist from Crotalaria albida. | 2017 | Details |
| A16366 | 28436198 | Mol Nutr Food Res | Effects of selenium on apoptosis and abnormal amino acid metabolism induced by excess fatty acid in isolated rat hepatocytes. | 2017 | Details |
| A16372 | 28430371 | APMIS | Evaluation of circulating zonulin as a potential marker in the pathogenesis of nonalcoholic fatty liver disease. | 2017 | Details |
| A16376 | 28428634 | Nat Rev Gastroenterol Hepatol | Lipid droplets and liver disease: from basic biology to clinical implications. | 2017 | Details |
| A16377 | 28428362 | J Endocrinol | Hepatic lipid accumulation: cause and consequence of dysregulated glucoregulatory hormones. | 2017 | Details |
| A16387 | 28425154 | Hepatol Res | Rifaximin in non-alcoholic steatohepatitis: An open-label pilot study. | 2017 | Details |
| A16388 | 28424263 | J Biol Chem | The kielin/chordin-like protein (KCP) attenuates high-fat diet-induced obesity and metabolic syndrome in mice. | 2017 | Details |
| A16394 | 28420094 | Nutrients | Nonalcoholic Fatty Liver Disease and Insulin Resistance: New Insights and Potential New Treatments. | 2017 | Details |
| A16401 | 28417532 | Diabetes Obes Metab | Non-alcoholic fatty liver disease (NAFLD) prevalence and its metabolic associations in patients with type 1 diabetes and type 2 diabetes. | 2017 | Details |
| A16407 | 28414056 | Eur J Pharmacol | Protective effects of glycyrrhizic acid against non-alcoholic fatty liver disease in mice. | 2017 | Details |
| A16411 | 28411267 | Diabetes | NFE2 Induces miR-423-5p to Promote Gluconeogenesis and Hyperglycemia by Repressing the Hepatic FAM3A-ATP-Akt Pathway. | 2017 | Details |
| A16412 | 28411170 | Biochim Biophys Acta Biomembr | The critical role of phosphatidylcholine and phosphatidylethanolamine metabolism in health and disease. | 2017 | Details |
| A16423 | 28402022 | J Cell Biochem | Steroidogenic Acute Regulatory Protein (StAR) Overexpression Reduces Inflammation and Insulin Resistance in Obese Mice. | 2017 | Details |
| A16429 | 28395666 | Lipids Health Dis | Hydroxytyrosol prevents reduction in liver activity of Δ-5 and Δ-6 desaturases, oxidative stress, and depletion in long chain polyunsaturated fatty acid content in different tissues of high-fat diet fed mice. | 2017 | Details |
| A16435 | 28391883 | J Clin Lipidol | Childhood/adult-onset lysosomal acid lipase deficiency: A serious metabolic and vascular phenotype beyond liver disease-four new pediatric cases. | 2016 | Details |
| A16440 | 28387617 | J Med Food | Oral Administration of β-Glucosylceramide for the Treatment of Insulin Resistance and Nonalcoholic Steatohepatitis: Results of a Double-Blind, Placebo-Controlled Trial. | 2017 | Details |
| A16457 | 28376109 | PLoS One | Association of leukocyte cell-derived chemotaxin 2 (LECT2) with NAFLD, metabolic syndrome, and atherosclerosis. | 2017 | Details |
| A16460 | 28375109 | Pak J Pharm Sci | Anti hyperlipidemic and hepatoprotective effects of native date fruit variety "Aseel" (Phoenix dactylifera). | 2016 | Details |
| A16463 | 28373762 | World J Gastroenterol | Traditional Chinese herbal extracts inducing autophagy as a novel approach in therapy of nonalcoholic fatty liver disease. | 2017 | Details |
| A16465 | 28371475 | J Diabetes Investig | Impact of non-alcoholic fatty pancreas disease on glucose metabolism. | 2017 | Details |
| A16466 | 28371239 | Liver Int | The Mediterranean dietary pattern as the diet of choice for non-alcoholic fatty liver disease: Evidence and plausible mechanisms. | 2017 | Details |
| A16467 | 28370150 | Aliment Pharmacol Ther | Polycystic ovary syndrome with hyperandrogenism as a risk factor for non-obese non-alcoholic fatty liver disease. | 2017 | Details |
| A16477 | 28365930 | J BUON | Hepatocellular carcinoma development in non-alcoholic fatty liver disease and non-alcoholic steatohepatitis. Is it going to be the "Plague" of the 21st century? A literature review focusing on pathogenesis, prevention and treatment. | 2017 | Details |
| A16478 | 28365312 | J Hepatol | Activating transcription factor 3 is a target molecule linking hepatic steatosis to impaired glucose homeostasis. | 2017 | Details |
| A16479 | 28364816 | Clin Liver Dis | De Novo and Recurrence of Nonalcoholic Steatohepatitis After Liver Transplantation. | 2017 | Details |
| A16489 | 28358620 | Metab Syndr Relat Disord | Daily Coffee Intake Inhibits Pancreatic Beta Cell Damage and Nonalcoholic Steatohepatitis in a Mouse Model of Spontaneous Metabolic Syndrome, Tsumura-Suzuki Obese Diabetic Mice. | 2017 | Details |
| A16503 | 28349245 | J Gastroenterol | Effect of miglitol on the suppression of nonalcoholic steatohepatitis development and improvement of the gut environment in a rodent model. | 2017 | Details |
| A16507 | 28348479 | World J Gastroenterol | Non-alcoholic fatty liver disease connections with fat-free tissues: A focus on bone and skeletal muscle. | 2017 | Details |
| A16515 | 28346237 | Curr Opin Gastroenterol | Current and future pharmacologic treatment of nonalcoholic steatohepatitis. | 2017 | Details |
| A16520 | 28341541 | Mol Aspects Med | Pro-resolving actions of SPM in adipose tissue biology. | 2017 | Details |
| A16529 | 28334911 | Hum Mol Genet | MERTK rs4374383 variant predicts incident nonalcoholic fatty liver disease and diabetes: role of mononuclear cell activation and adipokine response to dietary fat. | 2017 | Details |
| A16532 | 28332619 | Sci Rep | Retinol Binding Protein-4 Levels and Non-alcoholic Fatty Liver Disease: A community-based cross-sectional study. | 2017 | Details |
| A16534 | 28330852 | FASEB J | A controlled-release mitochondrial protonophore reverses hypertriglyceridemia, nonalcoholic steatohepatitis, and diabetes in lipodystrophic mice. | 2017 | Details |
| A16537 | 28327588 | Nat Commun | Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice. | 2017 | Details |
| A16539 | 28325853 | Diabetes | Deletion of Macrophage Mineralocorticoid Receptor Protects Hepatic Steatosis and Insulin Resistance Through ERα/HGF/Met Pathway. | 2017 | Details |
| A16541 | 28325476 | Arab J Gastroenterol | Erectile dysfunction in patients with nonalcoholic fatty liver disease. | 2017 | Details |
| A16543 | 28324110 | J Clin Endocrinol Metab | Effects of Metreleptin in Pediatric Patients With Lipodystrophy. | 2017 | Details |
| A16545 | 28323952 | J Clin Endocrinol Metab | Randomized Controlled Trial of a MUFA or Fiber-Rich Diet on Hepatic Fat in Prediabetes. | 2017 | Details |
| A16557 | 28318525 | Actas Dermosifiliogr | Psoriasis and Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A16564 | 28306139 | Br J Pharmacol | The TIR/BB-loop mimetic AS-1 prevents non-alcoholic steatohepatitis and hepatic insulin resistance by inhibiting NLRP3-ASC inflammasome activation. | 2017 | Details |
| A16566 | 28303724 | Drug Metab Rev | Non-alcoholic fatty liver disease (NAFLD) - pathogenesis, classification, and effect on drug metabolizing enzymes and transporters. | 2017 | Details |
| A16568 | 28300221 | Sci Rep | Beneficial effects of paeoniflorin on non-alcoholic fatty liver disease induced by high-fat diet in rats. | 2017 | Details |
| A16571 | 28299304 | Adv Biomed Res | Effects of Phlebotomy on Liver Enzymes and Histology of Patients with Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A16588 | 28297775 | Zhonghua Gan Zang Bing Za Zhi | [Effect of calcium-independent phospholipase A(2) inhibitor in reducing hepatocyte lipoapoptosis and improving insulin resistance]. | 2017 | Details |
| A16593 | 28294174 | Eur J Clin Nutr | Docosahexaenoic acid enrichment in NAFLD is associated with improvements in hepatic metabolism and hepatic insulin sensitivity: a pilot study. | 2017 | Details |