Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A20091 | 26160475 | Clin Res Hepatol Gastroenterol | Genetic polymorphisms and oxidative stress in non-alcoholic steatohepatitis (NASH): A mini review. | 2015 | Details |
| A20115 | 26147081 | Nature | The CREB coactivator CRTC2 controls hepatic lipid metabolism by regulating SREBP1. | 2015 | Details |
| A20137 | 26133486 | Int J Mol Med | Treatment with PPARδ agonist alleviates non-alcoholic fatty liver disease by modulating glucose and fatty acid metabolic enzymes in a rat model. | 2015 | Details |
| A20138 | 26133299 | Eur J Nutr | Bee's honey attenuates non-alcoholic steatohepatitis-induced hepatic injury through the regulation of thioredoxin-interacting protein-NLRP3 inflammasome pathway. | 2015 | Details |
| A20139 | 26133108 | Clin Transl Gastroenterol | Increased Serum Levels of LIGHT/TNFSF14 in Nonalcoholic Fatty Liver Disease: Possible Role in Hepatic Inflammation. | 2015 | Details |
| A20144 | 26126685 | Am J Physiol Endocrinol Metab | Characterization of lipid metabolism in a novel immortalized human hepatocyte cell line. | 2015 | Details |
| A20154 | 26120584 | Biomed Res Int | The Dual Role of Nrf2 in Nonalcoholic Fatty Liver Disease: Regulation of Antioxidant Defenses and Hepatic Lipid Metabolism. | 2015 | Details |
| A20162 | 26116377 | Arch Biochem Biophys | Loss of L-FABP, SCP-2/SCP-x, or both induces hepatic lipid accumulation in female mice. | 2015 | Details |
| A20166 | 26114447 | Food Funct | Caffeine ameliorates high energy diet-induced hepatic steatosis: sirtuin 3 acts as a bridge in the lipid metabolism pathway. | 2015 | Details |
| A20170 | 26113868 | Evid Based Complement Alternat Med | Effects on Liver Lipid Metabolism of the Naturally Occurring Dietary Flavone Luteolin-7-glucoside. | 2015 | Details |
| A20175 | 26108973 | Eur J Clin Invest | Ursodeoxycholyl Lysophosphatidylethanolamide modifies aberrant lipid profiles in NAFLD. | 2015 | Details |
| A20180 | 26103964 | BMC Gastroenterol | Differential hepatotoxicity of dietary and DNL-derived palmitate in the methionine-choline-deficient model of steatohepatitis. | 2015 | Details |
| A20181 | 26102213 | Nutrients | Hepatic Steatosis as a Marker of Metabolic Dysfunction. | 2015 | Details |
| A20183 | 26100857 | Nat Commun | A metabolic stress-inducible miR-34a-HNF4α pathway regulates lipid and lipoprotein metabolism. | 2015 | Details |
| A20190 | 26094890 | Cell Metab | Jejunal T Cell Inflammation in Human Obesity Correlates with Decreased Enterocyte Insulin Signaling. | 2015 | Details |
| A20225 | 26078098 | J Physiol Biochem | FTO-dependent function of N6-methyladenosine is involved in the hepatoprotective effects of betaine on adolescent mice. | 2015 | Details |
| A20228 | 26076903 | Annu Rev Nutr | Autophagy and Lipid Droplets in the Liver. | 2015 | Details |
| A20230 | 26076555 | Rom J Intern Med | Chronic Kidney Disease--Chronic Liver Disease. An Immunologic Cross-talk. | 2015 | Details |
| A20233 | 26073454 | Prog Lipid Res | Strategies, models and biomarkers in experimental non-alcoholic fatty liver disease research. | 2015 | Details |
| A20234 | 26072069 | J Huazhong Univ Sci Technolog Med Sci | Review on the effect of glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors for the treatment of non-alcoholic fatty liver disease. | 2015 | Details |
| A20237 | 26070860 | Expert Rev Gastroenterol Hepatol | Physiology and pathophysiology of liver lipid metabolism. | 2015 | Details |
| A20259 | 26058864 | Am J Physiol Endocrinol Metab | Cross-talk between branched-chain amino acids and hepatic mitochondria is compromised in nonalcoholic fatty liver disease. | 2015 | Details |
| A20263 | 26056853 | Toxicol Mech Methods | Perfluorononanoic acid disturbed the metabolism of lipid in the liver of streptozotocin-induced diabetic rats. | 2015 | Details |
| A20266 | 26055348 | Nutr Res | Resveratrol prevents hepatic steatosis and endoplasmic reticulum stress and regulates the expression of genes involved in lipid metabolism, insulin resistance, and inflammation in rats. | 2015 | Details |
| A20268 | 26052390 | World J Hepatol | Peroxisome proliferator-activated receptors as targets to treat non-alcoholic fatty liver disease. | 2015 | Details |
| A20272 | 26052375 | World J Hepatol | Pathophysiological mechanisms involved in non-alcoholic steatohepatitis and novel potential therapeutic targets. | 2015 | Details |
| A20277 | 26049666 | Clin Investig Arterioscler | [Role of metabolic lipases and lipotoxicity in the development of non-alcoholic steatosis and non-alcoholic steatohepatitis]. | 2015 | Details |
| A20279 | 26047899 | Int J Biol Macromol | Protective effects of Ginkgo biloba leaf polysaccharide on nonalcoholic fatty liver disease and its mechanisms. | 2015 | Details |
| A20280 | 26047766 | Clin Nutr | Omega-3 polyunsaturated fatty acids in treating non-alcoholic steatohepatitis: A randomized, double-blind, placebo-controlled trial. | 2015 | Details |
| A20283 | 26046396 | Nutrients | Low-Density Lipoprotein Receptor-Related Protein 6 (LRP6) Is a Novel Nutritional Therapeutic Target for Hyperlipidemia, Non-Alcoholic Fatty Liver Disease, and Atherosclerosis. | 2015 | Details |
| A20288 | 26045279 | Dig Dis | Use of farnesoid X receptor agonists to treat nonalcoholic fatty liver disease. | 2015 | Details |
| A20297 | 26040363 | Nutr Hosp | Effect of the intake of liquids rich in polyphenols on blood pressure and fat liver deposition in rats submitted to high-fat diet. | 2015 | Details |
| A20302 | 26039731 | PLoS One | Intravenous Mycobacterium Bovis Bacillus Calmette-Guérin Ameliorates Nonalcoholic Fatty Liver Disease in Obese, Diabetic ob/ob Mice. | 2015 | Details |
| A20308 | 26036873 | Electrophoresis | Comparative proteomic analysis using 2DE-LC-MS/MS reveals the mechanism of Fuzhuan brick tea extract against hepatic fat accumulation in rats with nonalcoholic fatty liver disease. | 2015 | Details |
| A20309 | 26035752 | Int J Mol Sci | Effect of Chronic Pioglitazone Treatment on Hepatic Gene Expression Profile in Obese C57BL/6J Mice. | 2015 | Details |
| A20315 | 26033245 | Mol Cell Endocrinol | Hepatic NAD salvage pathway is enhanced in mice on a high-fat diet. | 2015 | Details |
| A20316 | 26032587 | Pharmacol Res | Dihydromyricetin improves glucose and lipid metabolism and exerts anti-inflammatory effects in nonalcoholic fatty liver disease: A randomized controlled trial. | 2015 | Details |
| A20324 | 26028044 | Curr Drug Targets | Natural Products on Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A20330 | 26026390 | Gastroenterology | High Prevalence of Nonalcoholic Fatty Liver Disease in Adolescents Undergoing Bariatric Surgery. | 2015 | Details |
| A20332 | 26025327 | J Nutr Biochem | Bergamot polyphenol fraction prevents nonalcoholic fatty liver disease via stimulation of lipophagy in cafeteria diet-induced rat model of metabolic syndrome. | 2015 | Details |
| A20336 | 26024755 | Metabolism | Niacin inhibits fat accumulation, oxidative stress, and inflammatory cytokine IL-8 in cultured hepatocytes: Impact on non-alcoholic fatty liver disease. | 2015 | Details |
| A20356 | 26018346 | Mol Med Rep | Intrahepatic transplantation of adipose-derived stem cells attenuates the progression of non-alcoholic fatty liver disease in rats. | 2015 | Details |
| A20361 | 26017323 | Int J Food Sci Nutr | Effects of eicosapentaenoic acid on hepatic dyslipidemia and oxidative stress in high fat diet-induced steatosis. | 2015 | Details |
| A20364 | 26015548 | Diabetes | Growth Hormone Inhibits Hepatic De Novo Lipogenesis in Adult Mice. | 2015 | Details |
| A20365 | 26013469 | J Nutr Biochem | Platelet-activating factor modulates fat storage in the liver induced by a high-refined carbohydrate-containing diet. | 2015 | Details |
| A20375 | 26004139 | Exp Gerontol | Aging impairs the hepatic subcellular distribution of ChREBP in response to fasting/feeding in rats: Implications on hepatic steatosis. | 2015 | Details |
| A20379 | 26003186 | Eur J Nutr | Moderate alcohol consumption diminishes the development of non-alcoholic fatty liver disease (NAFLD) in ob/ob mice. | 2015 | Details |
| A20400 | 25992705 | Proc Nutr Soc | Relevance of liver fat to the impact of dietary extrinsic sugars on lipid metabolism. | 2015 | Details |
| A20418 | 25979856 | Eur J Pharmacol | An experimental study on amelioration of dyslipidemia-induced atherosclesis by Clematichinenoside through regulating Peroxisome proliferator-activated receptor-α mediated apolipoprotein A-I, A-II and C-III. | 2015 | Details |
| A20420 | 25976242 | Acta Diabetol | GCKR polymorphism influences liver fat content in patients with type 2 diabetes. | 2015 | Details |
| A20423 | 25974699 | Annu Rev Nutr | Health Benefits of Long-Term Weight-Loss Maintenance. | 2015 | Details |
| A20426 | 25974206 | Sci Rep | Chronic inflammation aggravates metabolic disorders of hepatic fatty acids in high-fat diet-induced obese mice. | 2015 | Details |
| A20430 | 25972092 | Biol Pharm Bull | Paeoniflorin Protects against Nonalcoholic Fatty Liver Disease Induced by a High-Fat Diet in Mice. | 2015 | Details |
| A20452 | 25954315 | Evid Based Complement Alternat Med | Vitex agnus-castus L. (Verbenaceae) Improves the Liver Lipid Metabolism and Redox State of Ovariectomized Rats. | 2015 | Details |
| A20453 | 25952508 | Lipids Health Dis | Mechanism of the effect of glycosyltransferase GLT8D2 on fatty liver. | 2015 | Details |
| A20454 | 25951637 | Zhongguo Zhong Xi Yi Jie He Za Zhi | [Intervention of berberine on lipid deposition in liver cells of non-alcoholic fatty liver disease rats induced by high fat diet]. | 2015 | Details |
| A20458 | 25948673 | Am J Clin Nutr | Association of serum retinoic acid with hepatic steatosis and liver injury in nonalcoholic fatty liver disease. | 2015 | Details |
| A20466 | 25943029 | Mol Nutr Food Res | Resveratrol improves hepatic steatosis by inducing autophagy through the cAMP signaling pathway. | 2015 | Details |
| A20481 | 25934505 | Genes Dev | Loss of the RNA polymerase III repressor MAF1 confers obesity resistance. | 2015 | Details |
| A20486 | 25933096 | PLoS One | OXPHOS-Mediated Induction of NAD+ Promotes Complete Oxidation of Fatty Acids and Interdicts Non-Alcoholic Fatty Liver Disease. | 2015 | Details |
| A20498 | 25921304 | J Lipid Res | Sin3A-associated protein, 18 kDa, a novel binding partner of TRIB1, regulates MTTP expression. | 2015 | Details |
| A20510 | 25915743 | Nutr Diabetes | Effect of multiple binge alcohol on diet-induced liver injury in a mouse model of obesity. | 2015 | Details |
| A20511 | 25915484 | Curr Drug Targets | Antioxidant Mechanisms in Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A20522 | 25910858 | Environ Toxicol Pharmacol | Nonalcoholic fatty liver disease induced by 13-week oral administration of 1,3-dichloro-2-propanol in C57BL/6J mice. | 2015 | Details |
| A20544 | 25897647 | Crit Rev Food Sci Nutr | The potential of flavonoids in the treatment of non-alcoholic fatty liver disease. | 2017 | Details |
| A20550 | 25892963 | Int J Biol Sci | ER stress and autophagy dysfunction contribute to fatty liver in diabetic mice. | 2015 | Details |
| A20553 | 25892149 | Food Funct | Ursolic acid inhibits the development of nonalcoholic fatty liver disease by attenuating endoplasmic reticulum stress. | 2015 | Details |
| A20555 | 25890430 | Obes Res Clin Pract | Soy β-conglycinin improves obesity-induced metabolic abnormalities in a rat model of nonalcoholic fatty liver disease. | 2014 | Details |
| A20563 | 25882223 | Curr Drug Targets | Targeting the Gut Microbiota for the Treatment of Non-Alcoholic Fatty Liver Disease. | 2015 | Details |
| A20564 | 25881230 | BMC Gastroenterol | Deficiency of iNOS-derived NO accelerates lipid accumulation-independent liver fibrosis in non-alcoholic steatohepatitis mouse model. | 2015 | Details |
| A20565 | 25880979 | Zhonghua Gan Zang Bing Za Zhi | [Effect of apigenin on protein expressions of PPARs in liver tissues of rats with nonalcoholic steatohepatitis]. | 2015 | Details |
| A20576 | 25875942 | PLoS One | LPSF/GQ-02 inhibits the development of hepatic steatosis and inflammation in a mouse model of non-alcoholic fatty liver disease (NAFLD). | 2015 | Details |
| A20590 | 25869616 | J Endocrinol | 11β-HSD1 reduces metabolic efficacy and adiponectin synthesis in hypertrophic adipocytes. | 2015 | Details |
| A20594 | 25866366 | Sci Rep | Acute exercise does not decrease liver fat in men with overweight or NAFLD. | 2015 | Details |
| A20596 | 25865685 | Hepatobiliary Pancreat Dis Int | Beneficial mechanisms of aerobic exercise on hepatic lipid metabolism in non-alcoholic fatty liver disease. | 2015 | Details |
| A20613 | 25850622 | Curr Drug Targets | Identification of Lipid Species Linked to the Progression of Non-Alcoholic Fatty Liver Disease. | 2015 | Details |
| A20615 | 25850006 | Cardiovasc Diabetol | Serum fibroblast growth factor 21 levels is associated with lower extremity atherosclerotic disease in Chinese female diabetic patients. | 2015 | Details |
| A20643 | 25837920 | J Pharmacol Sci | Effect of oleoylethanolamide on diet-induced nonalcoholic fatty liver in rats. | 2014 | Details |
| A20655 | 25827944 | J Physiol Biochem | Liver delipidating effect of a combination of resveratrol and quercetin in rats fed an obesogenic diet. | 2015 | Details |
| A20669 | 25817233 | Life Sci | AMP-kinase pathway is involved in tumor necrosis factor alpha-induced lipid accumulation in human hepatoma cells. | 2015 | Details |
| A20678 | 25808650 | Curr Drug Targets | The link between Hepatic Vitamin A Metabolism and Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A20680 | 25805927 | World J Gastroenterol | Ghrelin-ghrelin O-acyltransferase system in the pathogenesis of nonalcoholic fatty liver disease. | 2015 | Details |
| A20687 | 25799309 | PLoS One | Overexpression of miR-155 in the liver of transgenic mice alters the expression profiling of hepatic genes associated with lipid metabolism. | 2015 | Details |
| A20699 | 25790917 | Biochim Biophys Acta | Peroxisomes compensate hepatic lipid overflow in mice with fatty liver. | 2015 | Details |
| A20705 | 25788585 | J Nutr | Childhood energy intake is associated with nonalcoholic fatty liver disease in adolescents. | 2015 | Details |
| A20714 | 25785003 | Int J Clin Exp Med | Association between nonalcoholic fatty liver disease and colorectal adenoma: a systematic review and meta-analysis. | 2015 | Details |
| A20718 | 25777368 | Genes Cells | Alcohol dehydrogenase 3 contributes to the protection of liver from nonalcoholic steatohepatitis. | 2015 | Details |
| A20739 | 25766252 | Sci Rep | Lipidomic-based investigation into the regulatory effect of Schisandrin B on palmitic acid level in non-alcoholic steatotic livers. | 2015 | Details |
| A20743 | 25763607 | J Clin Endocrinol Metab | Paradoxical dissociation between hepatic fat content and de novo lipogenesis due to PNPLA3 sequence variant. | 2015 | Details |
| A20748 | 25757271 | Yao Xue Xue Bao | [Recent advances in curcumin and its derivatives for treatment of liver diseases]. | 2014 | Details |
| A20760 | 25751727 | Int J Mol Sci | Potential epigenetic mechanism in non-alcoholic Fatty liver disease. | 2015 | Details |
| A20763 | 25748419 | Life Sci | Singular effects of PPAR agonists on nonalcoholic fatty liver disease of diet-induced obese mice. | 2015 | Details |
| A20787 | 25736031 | Clin Nutr | Effect of specific amino acids on hepatic lipid metabolism in fructose-induced non-alcoholic fatty liver disease. | 2015 | Details |
| A20788 | 25733650 | Am J Clin Nutr | High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice. | 2015 | Details |
| A20803 | 25727012 | Biochem Biophys Res Commun | Endoplasmic reticulum stress induces up-regulation of hepatic β-Klotho expression through ATF4 signaling pathway. | 2015 | Details |
| A20807 | 25723789 | Br J Nutr | Differential effects of habitual chow-based and semi-purified diets on lipid metabolism in lactating rats and their offspring. | 2015 | Details |
| A20808 | 25721504 | Science | Controlled-release mitochondrial protonophore reverses diabetes and steatohepatitis in rats. | 2015 | Details |
| A20814 | 25716160 | Arch Toxicol | In vitro assessment of drug-induced liver steatosis based on human dermal stem cell-derived hepatic cells. | 2015 | Details |
| A20822 | 25712622 | Mol Nutr Food Res | Quercetin ameliorates dysregulation of lipid metabolism genes via the PI3K/AKT pathway in a diet-induced mouse model of nonalcoholic fatty liver disease. | 2015 | Details |
| A20832 | 25706109 | Curr Drug Targets | Discovery of Novel Anti-Diabetic Drugs by Targeting Lipid Metabolism. | 2015 | Details |