Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A09453 | 31742325 | Clin Sci (Lond) | Processes exacerbating apoptosis in non-alcoholic steatohepatitis. | 2019 | Details |
| A09459 | 31737583 | Can J Gastroenterol Hepatol | Association between Smoking and Liver Fibrosis among Patients with Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09460 | 31737175 | Oxid Med Cell Longev | Evaluation of the Effect Derived from Silybin with Vitamin D and Vitamin E Administration on Clinical, Metabolic, Endothelial Dysfunction, Oxidative Stress Parameters, and Serological Worsening Markers in Nonalcoholic Fatty Liver Disease Patients. | 2019 | Details |
| A09462 | 31734987 | Zhonghua Gan Zang Bing Za Zhi | [Expert recommendations on standardized diagnosis and treatment for fatty liver disease in China (2019 revised edition)]. | 2019 | Details |
| A09463 | 31734856 | Intern Emerg Med | Liver alterations in anorexia nervosa are not caused by insulin resistance. | 2019 | Details |
| A09466 | 31733366 | J Pharmacol Toxicol Methods | Variation in diagnostic NAFLD/NASH read-outs in paired liver samples from rodent models. | 2019 | Details |
| A09470 | 31731454 | Int J Mol Sci | Role of High-Mobility Group Box-1 in Liver Pathogenesis. | 2019 | Details |
| A09471 | 31731325 | Australas J Dermatol | Prevalence of non-alcoholic fatty liver and liver fibrosis in patients with moderate-severe psoriasis: A cross-sectional cohort study. | 2019 | Details |
| A09473 | 31731005 | Contemp Clin Trials | A randomized, double-blind, multicenter, phase 2b study to evaluate the safety and efficacy of a combination of tropifexor and cenicriviroc in patients with nonalcoholic steatohepatitis and liver fibrosis: Study design of the TANDEM trial. | 2019 | Details |
| A09482 | 31727409 | Lancet | Resmetirom (MGL-3196) for the treatment of non-alcoholic steatohepatitis: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial. | 2019 | Details |
| A09488 | 31726115 | J Hepatol | A defect in endothelial autophagy occurs in patients with non-alcoholic steatohepatitis and promotes inflammation and fibrosis. | 2019 | Details |
| A09492 | 31724099 | Dig Dis Sci | Early Predictors of Cardiovascular Disease Risk in Nonalcoholic Fatty Liver Disease: Non-obese Versus Obese Patients. | 2019 | Details |
| A09495 | 31721770 | PLoS One | Factors influencing subclinical atherosclerosis in patients with biopsy-proven nonalcoholic fatty liver disease. | 2019 | Details |
| A09500 | 31718031 | Cancers (Basel) | A Role for the Biological Clock in Liver Cancer. | 2019 | Details |
| A09502 | 31717860 | Cells | The Role of Gut-Derived Microbial Antigens on Liver Fibrosis Initiation and Progression. | 2019 | Details |
| A09504 | 31717576 | Int J Mol Sci | The Burden of Hepatocellular Carcinoma in Non-Alcoholic Fatty Liver Disease: Screening Issue and Future Perspectives. | 2019 | Details |
| A09506 | 31717385 | Cells | Evaluation of NV556, a Novel Cyclophilin Inhibitor, as a Potential Antifibrotic Compound for Liver Fibrosis. | 2019 | Details |
| A09507 | 31717358 | Nutrients | Reduced Oxidative Stress and Enhanced FGF21 Formation in Livers of Endurance-Exercised Rats with Diet-Induced NASH. | 2019 | Details |
| A09513 | 31714842 | AJR Am J Roentgenol | Comparison of 2D Shear Wave Elastography, Transient Elastography, and MR Elastography for the Diagnosis of Fibrosis in Patients With Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09519 | 31711944 | Surg Obes Relat Dis | Systematic review and meta-analysis of Roux-en-Y gastric bypass against laparoscopic sleeve gastrectomy for amelioration of NAFLD using four criteria. | 2019 | Details |
| A09521 | 31711876 | Metabolism | Non-invasive diagnosis of non-alcoholic steatohepatitis and fibrosis with the use of omics and supervised learning: A proof of concept study. | 2019 | Details |
| A09528 | 31706905 | J Clin Lipidol | Niacin for treatment of nonalcoholic fatty liver disease (NAFLD): novel use for an old drug? | 2019 | Details |
| A09532 | 31705834 | Liver Int | Hypothetical treatment of patients with non-alcoholic steatohepatitis: Potential impact on important clinical outcomes. | 2019 | Details |
| A09533 | 31705824 | Hepatology | Patatin-Like Phospholipase Domain-Containing Protein 3 I148M and Liver Fat and Fibrosis Scores Predict Liver Disease Mortality in the U.S. Population. | 2020 | Details |
| A09537 | 31703268 | Int J Environ Res Public Health | Pharmacological Therapy of Non-Alcoholic Fatty Liver Disease: What Drugs Are Available Now and Future Perspectives. | 2019 | Details |
| A09538 | 31703079 | PLoS One | Serum miR-33a is associated with steatosis and inflammation in patients with non-alcoholic fatty liver disease after liver transplantation. | 2019 | Details |
| A09543 | 31701071 | Hepatol Commun | Cardiovascular Risk Categories in Patients With Nonalcoholic Fatty Liver Disease and the Role of Low-Density Lipoprotein Cholesterol. | 2019 | Details |
| A09545 | 31700054 | Sci Rep | Isorhamnetin Alleviates Steatosis and Fibrosis in Mice with Nonalcoholic Steatohepatitis. | 2019 | Details |
| A09548 | 31697972 | J Hepatol | Insulin sensitizer MSDC-0602K in non-alcoholic steatohepatitis: A randomized, double-blind, placebo-controlled phase IIb study. | 2019 | Details |
| A09550 | 31696817 | Curr Gene Ther | Non-coding RNA Associated Competitive Endogenous RNA Regulatory Network: Novel Therapeutic Approach in Liver Fibrosis. | 2019 | Details |
| A09552 | 31696690 | Clin Mol Hepatol | Application of transient elastography in nonalcoholic fatty liver disease. | 2019 | Details |
| A09556 | 31695252 | J Clin Exp Hepatol | Preventive Strategies for Nonalcoholic Fatty Liver Disease After Liver Transplantation. | 2019 | Details |
| A09562 | 31694082 | Diabetes Metab J | Severity of Nonalcoholic Fatty Liver Disease in Type 2 Diabetes Mellitus: Relationship between Nongenetic Factors and PNPLA3/HSD17B13 Polymorphisms. | 2019 | Details |
| A09565 | 31693695 | PLoS One | The impact of hepatic steatosis on portal hypertension. | 2019 | Details |
| A09568 | 31692390 | Expert Rev Gastroenterol Hepatol | Progress in promising anti-fibrotic therapies. | 2019 | Details |
| A09569 | 31692226 | Diabetes Obes Metab | Exenatide and dapagliflozin combination improves markers of liver steatosis and fibrosis in patients with type 2 diabetes. | 2019 | Details |
| A09574 | 31690932 | J Clin Endocrinol Metab | Targeted Analysis of Three Hormonal Systems Identifies Molecules Associated with the Presence and Severity of NAFLD. | 2020 | Details |
| A09576 | 31689883 | Foods | Agaricus brasiliensis KA21 May Prevent Diet-Induced Nash Through Its Antioxidant, Anti-Inflammatory, and Anti-Fibrotic Activities in the Liver. | 2019 | Details |
| A09578 | 31689560 | Cell Mol Gastroenterol Hepatol | A Functional Role of GAS6/TAM in Nonalcoholic Steatohepatitis Progression Implicates AXL as Therapeutic Target. | 2019 | Details |
| A09581 | 31688305 | Eur J Gastroenterol Hepatol | Correlation of serum zinc levels with pathological and laboratory findings in patients with nonalcoholic fatty liver disease. | 2020 | Details |
| A09584 | 31686762 | World J Gastroenterol | Ultrasound-based techniques for the diagnosis of liver steatosis. | 2019 | Details |
| A09596 | 31682309 | J Dig Dis | Development of new drugs for the treatment of nonalcoholic steatohepatitis. | 2019 | Details |
| A09602 | 31678261 | Food Chem Toxicol | Cigarette smoking differentially regulates inflammatory responses in a mouse model of nonalcoholic steatohepatitis depending on exposure time point. | 2019 | Details |
| A09604 | 31677889 | Nutr Metab Cardiovasc Dis | Insulin resistance, but not insulin response, during oral glucose tolerance test (OGTT) is associated to worse histological outcome in obese NAFLD. | 2019 | Details |
| A09608 | 31677195 | J Gastroenterol Hepatol | Effect of PNPLA3 polymorphism on diagnostic performance of various noninvasive markers for diagnosing and staging nonalcoholic fatty liver disease. | 2019 | Details |
| A09612 | 31675274 | Metab Syndr Relat Disord | Relevant Features in Nonalcoholic Steatohepatitis Determined Using Machine Learning for Feature Selection. | 2019 | Details |
| A09618 | 31673534 | Hepatobiliary Surg Nutr | Endogenously increased n-3 PUFA levels in fat-1 transgenic mice do not protect from non-alcoholic steatohepatitis. | 2019 | Details |
| A09622 | 31671785 | Nutrients | mir-101-3p Downregulation Promotes Fibrogenesis by Facilitating Hepatic Stellate Cell Transdifferentiation During Insulin Resistance. | 2019 | Details |
| A09627 | 31670060 | Pharmacol Rep | Hepatoprotective potential of 7,8-Dihydroxyflavone against alcohol and high-fat diet induced liver toxicity via attenuation of oxido-nitrosative stress and NF-κB activation. | 2019 | Details |
| A09632 | 31668396 | Mol Metab | PAR2 controls cholesterol homeostasis and lipid metabolism in nonalcoholic fatty liver disease. | 2019 | Details |
| A09633 | 31668391 | Mol Metab | miR-873-5p targets mitochondrial GNMT-Complex II interface contributing to non-alcoholic fatty liver disease. | 2019 | Details |
| A09640 | 31662869 | United European Gastroenterol J | Individualized risk prediction of significant fibrosis in non-alcoholic fatty liver disease using a novel nomogram. | 2019 | Details |
| A09641 | 31662868 | United European Gastroenterol J | Evaluation and comparison of six noninvasive tests for prediction of significant or advanced fibrosis in nonalcoholic fatty liver disease. | 2019 | Details |
| A09642 | 31661783 | Metabolites | A Lipidomic Analysis of Docosahexaenoic Acid (22:6, ω3) Mediated Attenuation of Western Diet Induced Nonalcoholic Steatohepatitis in Male Ldlr -/- Mice. | 2019 | Details |
| A09643 | 31661724 | Hepatol Res | Liver stiffness does not affect ultrasound-guided attenuation coefficient measurement in the evaluation of hepatic steatosis. | 2019 | Details |
| A09646 | 31660146 | Food Sci Nutr | Fermented black radish (Raphanus sativus L. var. niger) attenuates methionine and choline deficient diet-induced nonalcoholic fatty liver disease in mice. | 2019 | Details |
| A09650 | 31658974 | Diabetes Care | Economic and Clinical Burden of Nonalcoholic Steatohepatitis in Patients With Type 2 Diabetes in the U.S. | 2019 | Details |
| A09656 | 31657148 | Obesity (Silver Spring) | Ratio of Conjugated Chenodeoxycholic to Muricholic Acids is Associated with Severity of Nonalcoholic Steatohepatitis. | 2019 | Details |
| A09657 | 31657145 | Pediatr Obes | Severe obesity is associated with liver disease severity in pediatric non-alcoholic fatty liver disease. | 2019 | Details |
| A09660 | 31656024 | Hormones (Athens) | Potential clinical variants detected in mitochondrial DNA D-loop hypervariable region I of patients with non-alcoholic steatohepatitis. | 2019 | Details |
| A09661 | 31655133 | J Hepatol | β-Klotho gene variation is associated with liver damage in children with NAFLD. | 2019 | Details |
| A09663 | 31654131 | J Gastroenterol | Accuracy of liver stiffness measurement and controlled attenuation parameter using FibroScan® M/XL probes to diagnose liver fibrosis and steatosis in patients with nonalcoholic fatty liver disease: a multicenter prospective study. | 2019 | Details |
| A09668 | 31652837 | Cancers (Basel) | Deregulated Lysophosphatidic Acid Metabolism and Signaling in Liver Cancer. | 2019 | Details |
| A09670 | 31652636 | Cells | MicroRNA-29a Suppresses CD36 to Ameliorate High Fat Diet-Induced Steatohepatitis and Liver Fibrosis in Mice. | 2019 | Details |
| A09671 | 31652578 | Int J Mol Sci | The SGLT2 Inhibitor Canagliflozin Prevents Carcinogenesis in a Mouse Model of Diabetes and Non-Alcoholic Steatohepatitis-Related Hepatocarcinogenesis: Association with SGLT2 Expression in Hepatocellular Carcinoma. | 2019 | Details |
| A09677 | 31651653 | Eur J Gastroenterol Hepatol | The diagnostic utility of fibrosis-4 or nonalcoholic fatty liver disease fibrosis score combined with liver stiffness measurement by fibroscan in assessment of advanced liver fibrosis: a biopsy-proven nonalcoholic fatty liver disease study. | 2020 | Details |
| A09681 | 31650383 | Mol Biol Rep | High fructose-containing drinking water-induced steatohepatitis in rats is prevented by the nicotinamide-mediated modulation of redox homeostasis and NADPH-producing enzymes. | 2019 | Details |
| A09685 | 31649787 | Prz Gastroenterol | Non-alcoholic fatty liver disease in Poland: how and at what stage is diagnosed, and how is treated. A survey study. | 2019 | Details |
| A09688 | 31647137 | J Ultrasound Med | Ultrasound Fatty Liver Indicator: A Simple Tool for Differentiating Steatosis From Nonalcoholic Steatohepatitis: Validity in the Average Obese Population. | 2019 | Details |
| A09690 | 31646583 | Eur Rev Med Pharmacol Sci | Key molecular pathways in the progression of non-alcoholic steatohepatitis. | 2019 | Details |
| A09691 | 31645988 | BMJ Open Gastroenterol | Relationship between Streptococcus mutans expressing Cnm in the oral cavity and non-alcoholic steatohepatitis: a pilot study. | 2019 | Details |
| A09692 | 31645727 | Nature | Somatic mutations and clonal dynamics in healthy and cirrhotic human liver. | 2019 | Details |
| A09695 | 31644993 | J Neurol Sci | Association between nonalcoholic fatty liver disease with advanced fibrosis and stroke. | 2019 | Details |
| A09696 | 31643035 | Dig Dis Sci | Nonalcoholic Fatty Liver Disease Among Individuals with HIV Mono-infection: A Growing Concern? | 2019 | Details |
| A09697 | 31642599 | HIV Med | Application of guidelines for the management of nonalcoholic fatty liver disease in three prospective cohorts of HIV-monoinfected patients. | 2019 | Details |
| A09698 | 31641351 | Int J Endocrinol | RAGE is a Potential Cause of Onset and Progression of Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09707 | 31638172 | Int J Mol Med | The A3 adenosine receptor agonist, namodenoson, ameliorates non‑alcoholic steatohepatitis in mice. | 2019 | Details |
| A09709 | 31637670 | Obes Surg | What Is the Role of the New Index Relative Fat Mass (RFM) in the Assessment of Nonalcoholic Fatty Liver Disease (NAFLD)? | 2020 | Details |
| A09711 | 31637181 | J Transl Int Med | Effect of Weight Reduction on Histological Activity and Fibrosis of Lean Nonalcoholic Steatohepatitis Patient. | 2019 | Details |
| A09714 | 31635469 | Vnitr Lek | Serum markers in diagnostics of steatohepatitis. | 2019 | Details |
| A09715 | 31635468 | Vnitr Lek | Non-Alcoholic Fatty Liver Disease. | 2019 | Details |
| A09716 | 31635436 | Cells | Increased Expression of RUNX1 in Liver Correlates with NASH Activity Score in Patients with Non-Alcoholic Steatohepatitis (NASH). | 2019 | Details |
| A09717 | 31635053 | Cells | Magnetic-Assisted Treatment of Liver Fibrosis. | 2019 | Details |
| A09719 | 31634581 | Clin Gastroenterol Hepatol | Health Care Costs of Patients With Biopsy-Confirmed Nonalcoholic Fatty Liver Disease Are Nearly Twice Those of Matched Controls. | 2019 | Details |
| A09724 | 31633721 | Arq Gastroenterol | EVALUATION OF PROGRESSION OF HEPATIC FIBROSIS IN A GROUP OF PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE ACCOMPANIED FOR 10 YEARS. | 2019 | Details |
| A09726 | 31633654 | J Pediatr Gastroenterol Nutr | Evaluation of Quantitative Imaging Biomarkers for Early-phase Clinical Trials of Steatohepatitis in Adolescents. | 2020 | Details |
| A09730 | 31632525 | Am J Transl Res | Neuregulin 4 attenuate tubulointerstitial fibrosis and advanced glycosylation end products accumulation in diabetic nephropathy rats via regulating TNF-R1 signaling. | 2019 | Details |
| A09739 | 31630534 | Am J Physiol Gastrointest Liver Physiol | Comparison of murine steatohepatitis models identifies a dietary intervention with robust fibrosis, ductular reaction, and rapid progression to cirrhosis and cancer. | 2019 | Details |
| A09743 | 31629366 | Endocr Rev | Nonalcoholic Fatty Liver Disease in Adults: Current Concepts in Etiology, Outcomes, and Management. | 2020 | Details |
| A09748 | 31627351 | Medicina (Kaunas) | Ultrasonographic Evaluation of Fatty Pancreas in Serbian Patients with Non Alcoholic Fatty Liver Disease-A Cross Sectional Study. | 2019 | Details |
| A09749 | 31627243 | Liver Int | Polycystic ovary syndrome (PCOS) is associated with NASH severity and advanced fibrosis. | 2019 | Details |
| A09758 | 31622581 | Am J Med | Atrial Fibrillation and Heart Failure With Preserved Ejection Fraction in Patients With Nonalcoholic Fatty Liver Disease. | 2019 | Details |
| A09760 | 31621579 | Elife | Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease. | 2019 | Details |
| A09761 | 31620652 | Transl Gastroenterol Hepatol | Effect of alcohol consumption on nonalcoholic fatty liver disease. | 2019 | Details |
| A09763 | 31620616 | Yeungnam Univ J Med | Pharmacologic therapy for nonalcoholic steatohepatitis focusing on pathophysiology. | 2019 | Details |
| A09765 | 31619023 | Cells | Potential Therapeutic Application of Estrogen in Gender Disparity of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis. | 2019 | Details |
| A09768 | 31617224 | Aliment Pharmacol Ther | Direct comparison of the specialised blood fibrosis tests FibroMeterV2G and Enhanced Liver Fibrosis score in patients with non-alcoholic fatty liver disease from tertiary care centres. | 2019 | Details |
| A09771 | 31616384 | Front Endocrinol (Lausanne) | Inhibiting Ceramide Synthesis Attenuates Hepatic Steatosis and Fibrosis in Rats With Non-alcoholic Fatty Liver Disease. | 2019 | Details |
| A09778 | 31614590 | Int J Mol Sci | Liver X Receptors Regulate Cholesterol Metabolism and Immunity in Hepatic Nonparenchymal Cells. | 2019 | Details |
| A09779 | 31614491 | Int J Mol Sci | Development and Progression of Non-Alcoholic Fatty Liver Disease: The Role of Advanced Glycation End Products. | 2019 | Details |