Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Fructose1035 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A06589 | 32818435 | Cell Metab | Triose Kinase Controls the Lipogenic Potential of Fructose and Dietary Tolerance. | 2020 | Details |
| A06590 | 32816619 | Gut Microbes | Modifying macronutrients is superior to microbiome transplantation in treating nonalcoholic fatty liver disease. | 2020 | Details |
| A06592 | 32815965 | Food Funct | A multi-targeting strategy to ameliorate high-fat-diet- and fructose-induced (western diet-induced) non-alcoholic fatty liver disease (NAFLD) with supplementation of a mixture of legume ethanol extracts. | 2020 | Details |
| A06631 | 32800834 | Life Sci | High fructose intake and the route towards cardiometabolic diseases. | 2020 | Details |
| A06703 | 32775322 | Front Bioeng Biotechnol | Computational Modeling of Fructose Metabolism and Development in NAFLD. | 2020 | Details |
| A06719 | 32770818 | Liver Int | Steatosis as main determinant of portal hypertension through a restriction of hepatic sinusoidal area in a dietary rat nash model. | 2020 | Details |
| A06729 | 32767404 | Cell Biochem Funct | Apoptosis-inducing factor deficient mice fail to develop hepatic steatosis under high fat high fructose diet or bile duct ligation. | 2020 | Details |
| A06734 | 32765812 | Nutr Res Pract | Folic acid supplementation prevents high fructose-induced non-alcoholic fatty liver disease by activating the AMPK and LKB1 signaling pathways. | 2020 | Details |
| A06759 | 32757283 | Fundam Clin Pharmacol | Protective effect of fenofibrate against high-fat-high-fructose diet induced non-obese NAFLD in rats. | 2020 | Details |
| A06776 | 32751772 | Nutrients | Differential Effects of Chronic Ingestion of Refined Sugars versus Natural Sweeteners on Insulin Resistance and Hepatic Steatosis in a Rat Model of Diet-Induced Obesity. | 2020 | Details |
| A06792 | 32744096 | Am J Physiol Endocrinol Metab | Neurodegeneration in juvenile Iberian pigs with diet-induced nonalcoholic fatty liver disease. | 2020 | Details |
| A06805 | 32738448 | J Hepatol | Reduced Nogo expression inhibits diet-induced metabolic disorders by regulating ChREBP and insulin activity. | 2020 | Details |
| A06827 | 32733017 | Sci Rep | Determining the contribution of a high-fructose corn syrup formulation to hepatic glycogen synthesis during ad-libitum feeding in mice. | 2020 | Details |
| A06832 | 32730863 | Toxicol In Vitro | Fructose-palmitate based high calorie induce steatosis in HepG2 cells via mitochondrial dysfunction: An in vitro approach. | 2020 | Details |
| A06924 | 32696189 | Metab Brain Dis | Melatonin regulates neurodegenerative complications associated with NAFLD via enhanced neurotransmission and cellular integrity: a correlational study. | 2020 | Details |
| A06932 | 32694791 | Nat Metab | The small intestine shields the liver from fructose-induced steatosis. | 2020 | Details |
| A06968 | 32683952 | Am J Physiol Gastrointest Liver Physiol | Knockout of sulfatase 2 is associated with decreased steatohepatitis and fibrosis in a mouse model of nonalcoholic fatty liver disease. | 2020 | Details |
| A06978 | 32679144 | Life Sci | Oxymatrine alleviated hepatic lipid metabolism via regulating miR-182 in non-alcoholic fatty liver disease. | 2020 | Details |
| A06984 | 32673798 | Mol Metab | Non-alcoholic fatty liver disease and steatohepatitis: State of the art on effective therapeutics based on the gold standard method for diagnosis. | 2020 | Details |
| A06991 | 32670821 | J Tradit Complement Med | Beneficial effects of Chinese herbs in the treatment of fatty liver diseases. | 2020 | Details |
| A07003 | 32663815 | J Breath Res | High intestinal hydrogen production in runners after intake of fructose solution. | 2020 | Details |
| A07005 | 32663610 | Biochim Biophys Acta Mol Cell Biol Lipids | Glucosamine regulates hepatic lipid accumulation by sensing glucose levels or feeding states of normal and excess. | 2020 | Details |
| A07047 | 32643289 | Physiol Rep | Modifying nutritional substrates induces macrovesicular lipid droplet accumulation and metabolic alterations in a cellular model of hepatic steatosis. | 2020 | Details |
| A07050 | 32641615 | J Oleo Sci | Basil Essential Oil and Its Nanoemulsion Mitigate Non Alcoholic Steatohepatitis in Rat Model with Special Reference to Gut Microbiota. | 2020 | Details |
| A07051 | 32640454 | Pharmacology | Molecular Study on the Potential Protective Effects of Bee Venom against Fructose-Induced Nonalcoholic Steatohepatitis in Rats. | 2020 | Details |
| A07074 | 32631250 | BMC Gastroenterol | Human translatability of the GAN diet-induced obese mouse model of non-alcoholic steatohepatitis. | 2020 | Details |
| A07089 | 32626837 | Hepatol Commun | Activation of Adenosine Monophosphate-Activated Protein Kinase Reduces the Onset of Diet-Induced Hepatocellular Carcinoma in Mice. | 2020 | Details |
| A07116 | 32617026 | Hepat Med | Effect of Oral Administration of Weissella confusa on Fecal and Plasma Ethanol Concentrations, Lipids and Glucose Metabolism in Wistar Rats Fed High Fructose and Fat Diet. | 2020 | Details |
| A07149 | 32599713 | Int J Mol Sci | Fructose and Uric Acid: Major Mediators of Cardiovascular Disease Risk Starting at Pediatric Age. | 2020 | Details |
| A07150 | 32599319 | Int Immunopharmacol | Potential anti-inflammatory effect of dapagliflozin in HCHF diet- induced fatty liver degeneration through inhibition of TNF-α, IL-1β, and IL-18 in rat liver. | 2020 | Details |
| A07219 | 32577775 | Inflamm Res | Pathobiological and molecular connections involved in the high fructose and high fat diet induced diabetes associated nonalcoholic fatty liver disease. | 2020 | Details |
| A07227 | 32574624 | Gastroenterology | IRE1A Stimulates Hepatocyte-Derived Extracellular Vesicles That Promote Inflammation in Mice With Steatohepatitis. | 2020 | Details |
| A07322 | 32538722 | Curr Protein Pept Sci | Gut Barrier Proteins Mediate Liver Regulation by the Effects of Serotonin on the Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A07340 | 32531370 | Int J Biol Macromol | The protective effects of walnut green husk polysaccharide on liver injury, vascular endothelial dysfunction and disorder of gut microbiota in high fructose-induced mice. | 2020 | Details |
| A07436 | 32497536 | Metabolism | Fortifying diet with rapeseed oil instead of butterfat attenuates the progression of diet-induced non-alcoholic fatty liver disease (NAFLD) and impairment of glucose tolerance. | 2020 | Details |
| A07443 | 32494762 | Curr Dev Nutr | Targeted Nutrient Modifications in Purified Diets Differentially Affect Nonalcoholic Fatty Liver Disease and Metabolic Disease Development in Rodent Models. | 2020 | Details |
| A07473 | 32482167 | BMC Complement Med Ther | Genistein and exercise modulated lipid peroxidation and improved steatohepatitis in ovariectomized rats. | 2020 | Details |
| A07588 | 32434697 | Transl Res | Cathepsin B deficiency ameliorates liver lipid deposition, inflammatory cell infiltration, and fibrosis after diet-induced nonalcoholic steatohepatitis. | 2020 | Details |
| A07663 | 32405177 | J Clin Exp Hepatol | NASH-inducing Diets in Göttingen Minipigs. | 2019 | Details |
| A07756 | 32363320 | Hepatol Commun | Validation of PAS Kinase, a Regulator of Hepatic Fatty Acid and Triglyceride Synthesis, as a Therapeutic Target for Nonalcoholic Steatohepatitis. | 2020 | Details |
| A07768 | 32360637 | Cell Mol Gastroenterol Hepatol | Diet Reversal and Immune Modulation Show Key Role for Liver and Adipose Tissue T Cells in Murine Nonalcoholic Steatohepatitis. | 2020 | Details |
| A07850 | 32335723 | Appl Microbiol Biotechnol | Lactobacillus plantarum NA136 ameliorates nonalcoholic fatty liver disease by modulating gut microbiota, improving intestinal barrier integrity, and attenuating inflammation. | 2020 | Details |
| A07877 | 32325919 | Nutrients | Decreased Consumption of Added Fructose Reduces Waist Circumference and Blood Glucose Concentration in Patients with Overweight and Obesity. The DISFRUTE Study: A Randomised Trial in Primary Care. | 2020 | Details |
| A07898 | 32317687 | Sci Rep | Rebaudioside affords hepatoprotection ameliorating sugar sweetened beverage- induced nonalcoholic steatohepatitis. | 2020 | Details |
| A07909 | 32314395 | Lipids | High Glucose and Liver Fatty Acid Binding Protein Gene Ablation Differentially Impact Whole Body and Liver Phenotype in High-Fat Pair-Fed Mice. | 2020 | Details |
| A07930 | 32306652 | Zhonghua Gan Zang Bing Za Zhi | [Diagnosis and therapeutic strategies for non-obese type of non-alcoholic fatty liver diseases]. | 2020 | Details |
| A07966 | 32296880 | J Mol Med (Berl) | HIF-P4H-2 inhibition enhances intestinal fructose metabolism and induces thermogenesis protecting against NAFLD. | 2020 | Details |
| A07980 | 32290942 | Wei Sheng Yan Jiu | [Effects of lycopene on metabolism of glycolipid and inflammation in non-alcoholic fatty liver disease rats]. | 2020 | Details |
| A08084 | 32253274 | J Am Soc Nephrol | Fructose Production and Metabolism in the Kidney. | 2020 | Details |
| A08133 | 32235497 | Nutrients | Oral Supplementation of Sodium Butyrate Attenuates the Progression of Non-Alcoholic Steatohepatitis. | 2020 | Details |
| A08158 | 32223569 | Arch Physiol Biochem | Crosstalk between kidney and liver in non-alcoholic fatty liver disease: mechanisms and therapeutic approaches. | 2020 | Details |
| A08166 | 32220583 | J Hepatol | MLKL-dependent signaling regulates autophagic flux in a murine model of non-alcohol-associated fatty liver and steatohepatitis. | 2020 | Details |
| A08174 | 32218179 | Biomolecules | A Sweet Connection? Fructose's Role in Hepatocellular Carcinoma. | 2020 | Details |
| A08186 | 32214246 | Nature | Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate. | 2020 | Details |
| A08215 | 32200254 | Biomed Pharmacother | Hepalatide ameliorated progression of nonalcoholic steatohepatitis in mice. | 2020 | Details |
| A08219 | 32196896 | Diabetes Obes Metab | Incretin combination therapy for the treatment of non-alcoholic steatohepatitis. | 2020 | Details |
| A08247 | 32189355 | J Food Biochem | Silymarin attenuated nonalcoholic fatty liver disease through the regulation of endoplasmic reticulum stress proteins GRP78 and XBP-1 in mice. | 2020 | Details |
| A08250 | 32188531 | J Dev Orig Health Dis | Administration of ursolic acid to new-born pups prevents dietary fructose-induced non-alcoholic fatty liver disease in Sprague Dawley rats. | 2020 | Details |
| A08338 | 32148418 | J Ginseng Res | Ameliorative effects of black ginseng on nonalcoholic fatty liver disease in free fatty acid-induced HepG2 cells and high-fat/high-fructose diet-fed mice. | 2019 | Details |
| A08479 | 32093158 | Nutrients | Beneficial Effects of Lactobacillus plantarum Strains on Non-Alcoholic Fatty Liver Disease in High Fat/High Fructose Diet-Fed Rats. | 2020 | Details |
| A08557 | 32061907 | Metabolism | Established and emerging factors affecting the progression of nonalcoholic fatty liver disease. | 2020 | Details |
| A08580 | 32053033 | Expert Opin Ther Targets | Emerging therapeutic targets for NASH: key innovations at the preclinical level. | 2020 | Details |
| A08645 | 32033765 | Gastroenterol Clin North Am | Nutrition and Nonalcoholic Fatty Liver Disease: Current Perspectives. | 2019 | Details |
| A08712 | 32015322 | Cell Death Dis | Hepatocyte apoptosis is tumor promoting in murine nonalcoholic steatohepatitis. | 2020 | Details |
| A08732 | 32007822 | J Nutr Biochem | Effects of (-)-epicatechin on the time course of the expression of perilipins in a diet-induced model of nonalcoholic steatohepatitis. | 2019 | Details |
| A08745 | 32003601 | Am J Physiol Gastrointest Liver Physiol | Dysregulated FXR-FGF19 signaling and choline metabolism are associated with gut dysbiosis and hyperplasia in a novel pig model of pediatric NASH. | 2020 | Details |
| A08781 | 31986483 | J Nutr Biochem | Copper modulates sex-specific fructose hepatoxicity in nonalcoholic fatty liver disease (NALFD) Wistar rat models. | 2019 | Details |
| A08879 | 31953865 | Hepatology | Indole Alleviates Diet-Induced Hepatic Steatosis and Inflammation in a Manner Involving Myeloid Cell 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 3. | 2020 | Details |
| A08924 | 31936026 | Nutrients | All You Can Feed: Some Comments on Production of Mouse Diets Used in Biomedical Research with Special Emphasis on Non-Alcoholic Fatty Liver Disease Research. | 2020 | Details |
| A08925 | 31935815 | Int J Mol Sci | Antrodan Alleviates High-Fat and High-Fructose Diet-Induced Fatty Liver Disease in C57BL/6 Mice Model via AMPK/Sirt1/SREBP-1c/PPARγ Pathway. | 2020 | Details |
| A08928 | 31935149 | Crit Rev Clin Lab Sci | Fructose and hepatic insulin resistance. | 2020 | Details |
| A08939 | 31930826 | Pak J Biol Sci | <i>In vitro</i> Anticancer Activity of Quinoa and Safflower Seeds and Their Preventive Effects on Non-alcoholic Fatty Liver. | 2019 | Details |
| A08980 | 31916388 | Mol Nutr Food Res | Differentiated Hepatic Response to Fructose Intake during Adolescence Reveals the Increased Susceptibility to Non-Alcoholic Fatty Liver Disease of Maternal High-Fat Diet Male Rat Offspring. | 2020 | Details |
| A09009 | 31905727 | Nutrients | Intestinal Fructose and Glucose Metabolism in Health and Disease. | 2019 | Details |
| A09015 | 31903720 | Liver Int | Succinate-GPR-91 receptor signalling is responsible for nonalcoholic steatohepatitis-associated fibrosis: Effects of DHA supplementation. | 2020 | Details |
| A09079 | 31882668 | Sci Rep | Restoration of liver sinusoidal cell phenotypes by statins improves portal hypertension and histology in rats with NASH. | 2019 | Details |
| A09108 | 31870938 | Peptides | Endogenously released GIP reduces and GLP-1 increases hepatic insulin extraction. | 2019 | Details |
| A09121 | 31867104 | J Anim Sci Biotechnol | Hepatic metabolomics and transcriptomics to study susceptibility to ketosis in response to prepartal nutritional management. | 2019 | Details |
| A09193 | 31840865 | Nutr Clin Pract | Evolution of NAFLD and Its Management. | 2019 | Details |
| A09201 | 31838076 | Gastroenterology | Lactotrehalose, an Analog of Trehalose, Increases Energy Metabolism Without Promoting Clostridioides difficile Infection in Mice. | 2019 | Details |
| A09221 | 31832499 | GE Port J Gastroenterol | Fatty Liver Caused by Glycogen Storage Disease Type IX: A Small Series of Cases in Children. | 2019 | Details |
| A09224 | 31831621 | J Biol Chem | Disruption of hepatic small heterodimer partner induces dissociation of steatosis and inflammation in experimental nonalcoholic steatohepatitis. | 2019 | Details |
| A09308 | 31796953 | Am J Clin Nutr | Metabolic effects of a prolonged, very-high-dose dietary fructose challenge in healthy subjects. | 2020 | Details |
| A09362 | 31777715 | Pediatr Gastroenterol Hepatol Nutr | New Perspectives in Pediatric Nonalcoholic Fatty Liver Disease: Epidemiology, Genetics, Diagnosis, and Natural History. | 2019 | Details |
| A09363 | 31777643 | Int J Physiol Pathophysiol Pharmacol | Role of mitochondrial depolarization and disrupted mitochondrial homeostasis in non-alcoholic steatohepatitis and fibrosis in mice. | 2019 | Details |
| A09397 | 31760464 | Cell Mol Life Sci | Fructose-mediated effects on gene expression and epigenetic mechanisms associated with NAFLD pathogenesis. | 2020 | Details |
| A09399 | 31760308 | J Nutr Biochem | Probiotic culture supernatant improves metabolic function through FGF21-adiponectin pathway in mice. | 2019 | Details |
| A09443 | 31746883 | Food Funct | Artemisia sphaerocephala Krasch polysaccharide prevents hepatic steatosis in high fructose-fed mice associated with changes in the gut microbiota. | 2019 | Details |
| A09494 | 31721969 | Arq Gastroenterol | IMPACT OF CURRENT DIET AT THE RISK OF NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD). | 2020 | Details |
| A09507 | 31717358 | Nutrients | Reduced Oxidative Stress and Enhanced FGF21 Formation in Livers of Endurance-Exercised Rats with Diet-Induced NASH. | 2019 | Details |
| A09516 | 31713637 | Cell Mol Life Sci | Recent advances in the pathogenesis of hereditary fructose intolerance: implications for its treatment and the understanding of fructose-induced non-alcoholic fatty liver disease. | 2019 | Details |
| A09536 | 31705397 | J Endocrinol Invest | L-Carnitine counteracts in vitro fructose-induced hepatic steatosis through targeting oxidative stress markers. | 2019 | Details |
| A09634 | 31668386 | Mol Metab | Fibroblast growth factor 21 is required for the therapeutic effects of Lactobacillus rhamnosus GG against fructose-induced fatty liver in mice. | 2019 | Details |
| A09653 | 31657510 | Mol Nutr Food Res | The Buckwheat Iminosugar d-Fagomine Attenuates Sucrose-Induced Steatosis and Hypertension in Rats. | 2019 | Details |
| A09681 | 31650383 | Mol Biol Rep | High fructose-containing drinking water-induced steatohepatitis in rats is prevented by the nicotinamide-mediated modulation of redox homeostasis and NADPH-producing enzymes. | 2019 | Details |
| A09740 | 31630414 | Hepatology | Fatty Acid Synthase Inhibitor TVB-2640 Reduces Hepatic de Novo Lipogenesis in Males With Metabolic Abnormalities. | 2020 | Details |
| A09777 | 31614639 | Biomolecules | Allopurinol Prevents the Lipogenic Response Induced by an Acute Oral Fructose Challenge in Short-Term Fructose Fed Rats. | 2019 | Details |
| A09800 | 31604965 | Sci Rep | Depletion of CD40 on CD11c+ cells worsens the metabolic syndrome and ameliorates hepatic inflammation during NASH. | 2019 | Details |
| A09807 | 31602953 | Zhongguo Zhong Yao Za Zhi | [Mechanism of Calculus Bovis Sativus in inhibiting hepatocyte lipid deposition based on serum pharmacology]. | 2019 | Details |
| A09815 | 31599882 | Rev Invest Clin | INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-1, NON-ALCOHOLIC FATTY LIVER DISEASE, AND ITS RELATIONSHIP WITH FRUCTOSE CONSUMPTION IN CHILDREN WITH OBESITY. | 2019 | Details |