Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
stats1
stats2
stats3
stats4
Search for:
apoptosis1710 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A05574 | 33203036 | Int J Mol Sci | ASC, IL-18 and Galectin-3 as Biomarkers of Non-Alcoholic Steatohepatitis: A Proof of Concept Study. | 2020 | Details |
| A05631 | 33182043 | Int Immunopharmacol | Didymin ameliorates dexamethasone-induced non-alcoholic fatty liver disease by inhibiting TLR4/NF-κB and PI3K/Akt pathways in C57BL/6J mice. | 2020 | Details |
| A05650 | 33173107 | Sci Rep | Dipeptidyl peptidase-4 inhibitor protects against non-alcoholic steatohepatitis in mice by targeting TRAIL receptor-mediated lipoapoptosis via modulating hepatic dipeptidyl peptidase-4 expression. | 2020 | Details |
| A05678 | 33163831 | Hepatol Commun | Loss of Hepatic Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 Links Nonalcoholic Steatohepatitis to Atherosclerosis. | 2020 | Details |
| A05779 | 33122078 | Gene | TCTP participates in hepatic metabolism by regulating gene expression involved in insulin resistance. | 2020 | Details |
| A05799 | 33114290 | Int J Mol Sci | The Molecular Mechanisms of Iron Metabolism and Its Role in Cardiac Dysfunction and Cardioprotection. | 2020 | Details |
| A05819 | 33106416 | Proc Natl Acad Sci U S A | Stimulation of soluble guanylate cyclase exerts antiinflammatory actions in the liver through a VASP/NF-κB/NLRP3 inflammasome circuit. | 2020 | Details |
| A05839 | 33102796 | Endocrinol Diabetes Metab | The role of noninvasive biomarkers in diagnosis and risk stratification in nonalcoholic fatty liver disease. | 2020 | Details |
| A05840 | 33102794 | Endocrinol Diabetes Metab | The metabolic basis of nonalcoholic steatohepatitis. | 2020 | Details |
| A05911 | 33078424 | J Food Biochem | Role of potato protein hydrolysate and exercise in preventing high-fat diet-induced hepatocyte apoptosis in senescence-accelerated mouse. | 2020 | Details |
| A05929 | 33072754 | Front Cell Dev Biol | Role of Mitofusins and Mitophagy in Life or Death Decisions. | 2020 | Details |
| A05973 | 33055335 | Wiad Lek | APOPTOTIC PROCESSES' RESEARCH ON THE MODEL OF TYPE 2 DIABETES MELLITUS ON OBESITY'S BACKGROUND UNDER THE INFLUENCE OF DENSE BEAN EXTRACT. | 2020 | Details |
| A05983 | 33052067 | Am J Physiol Cell Physiol | Inositol-requiring enzyme 1α links palmitate-induced mTOR activation and lipotoxicity in hepatocytes. | 2020 | Details |
| A06011 | 33038432 | J Hepatol | Emricasan to prevent new decompensation in patients with NASH-related decompensated cirrhosis. | 2020 | Details |
| A06048 | 33028928 | Sci Rep | The effects of fructose and metabolic inhibition on hepatocellular carcinoma. | 2020 | Details |
| A06102 | 33007418 | Pharmacol Res | Endoplasmic reticulum stress and protein degradation in chronic liver disease. | 2020 | Details |
| A06122 | 32998095 | Diabetes Metab Syndr | Pathophysiological mechanisms underlying MAFLD. | 2020 | Details |
| A06135 | 32993055 | Int J Mol Sci | Prolonged Lipid Accumulation in Cultured Primary Human Hepatocytes Rather Leads to ER Stress than Oxidative Stress. | 2020 | Details |
| A06136 | 32992548 | Antioxidants (Basel) | Involvement of HO-1 and Autophagy in the Protective Effect of Magnolol in Hepatic Steatosis-Induced NLRP3 Inflammasome Activation In Vivo and In Vitro. | 2020 | Details |
| A06180 | 32978261 | J Biol Chem | ERAD deficiency promotes mitochondrial dysfunction and transcriptional rewiring in human hepatic cells. | 2020 | Details |
| A06223 | 32963259 | Sci Rep | Mechanistic study of attenuation of monosodium glutamate mixed high lipid diet induced systemic damage in rats by Coccinia grandis. | 2020 | Details |
| A06230 | 32961563 | Exp Clin Endocrinol Diabetes | Glucagon Like Peptide-1 Receptor Agonists Alter Pancreatic and Hepatic Histology and Regulation of Endoplasmic Reticulum Stress in High-fat Diet Mouse Model. | 2020 | Details |
| A06270 | 32945983 | Dig Dis Sci | FAM172A Deletion May Enhance Hepatic Steatosis by Promoting ER Stress. | 2020 | Details |
| A06289 | 32940033 | J Agric Food Chem | (-)-Hydroxycitric Acid Alleviates Oleic Acid-Induced Steatosis, Oxidative Stress, and Inflammation in Primary Chicken Hepatocytes by Regulating AMP-Activated Protein Kinase-Mediated Reactive Oxygen Species Levels. | 2020 | Details |
| A06364 | 32914480 | Phytother Res | Rosmarinic acid exerts an antagonistic effect on nonalcoholic fatty liver disease by regulating the YAP1/TAZ-PPARγ/PGC-1α signaling pathway. | 2020 | Details |
| A06382 | 32905826 | Toxicology | Dual TBK1/IKKε inhibitor amlexanox mitigates palmitic acid-induced hepatotoxicity and lipoapoptosis in vitro. | 2020 | Details |
| A06397 | 32893589 | Zhongguo Zhong Yao Za Zhi | [Effect and mechanism of Bidens pilosa decoction on non-alcoholic fatty liver induced by high fat and high glucose in mice]. | 2020 | Details |
| A06507 | 32849291 | Front Endocrinol (Lausanne) | Too Much of a Good Thing? An Evolutionary Theory to Explain the Role of Ceramides in NAFLD. | 2020 | Details |
| A06522 | 32841505 | Liver Int | Dual targeting of hepatic fibrosis and atherogenesis by icosabutate, an engineered eicosapentaenoic acid derivative. | 2020 | Details |
| A06552 | 32827918 | Int Immunopharmacol | Bavachinin inhibits cholesterol synthesis enzyme FDFT1 expression via AKT/mTOR/SREBP-2 pathway. | 2020 | Details |
| A06619 | 32805210 | Chem Biol Interact | High fat diet-triggered non-alcoholic fatty liver disease: A review of proposed mechanisms. | 2020 | Details |
| A06647 | 32795504 | Ageing Res Rev | Structure-functional implications of longevity protein p66Shc in health and disease. | 2020 | Details |
| A06649 | 32795119 | Metab Syndr Relat Disord | Omeprazole and Spirulina Platensis Ameliorate Steatohepatitis in Experimental Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A06673 | 32785100 | Diagnostics (Basel) | Surveillance of Hepatocellular Carcinoma in Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A06709 | 32774148 | Mediators Inflamm | Understanding the Role of Exercise in Nonalcoholic Fatty Liver Disease: ERS-Linked Molecular Pathways. | 2020 | Details |
| A06712 | 32773025 | Biol Aujourdhui | [Cell death mechanisms in non-alcoholic steatohepatitis]. | 2020 | Details |
| A06729 | 32767404 | Cell Biochem Funct | Apoptosis-inducing factor deficient mice fail to develop hepatic steatosis under high fat high fructose diet or bile duct ligation. | 2020 | Details |
| A06730 | 32766475 | Hepatol Commun | Lack of Augmenter of Liver Regeneration Disrupts Cholesterol Homeostasis of Liver in Mice by Inhibiting the AMPK Pathway. | 2020 | Details |
| A06753 | 32759548 | Biol Pharm Bull | Amelioration of the Lipogenesis, Oxidative Stress and Apoptosis of Hepatocytes by a Novel Proteoglycan from Ganoderma lucidum. | 2020 | Details |
| A06786 | 32746645 | Expert Rev Gastroenterol Hepatol | Clinical heterogeneity in patients with non-alcoholic fatty liver disease-associated hepatocellular carcinoma. | 2020 | Details |
| A06795 | 32742358 | Exp Ther Med | Pathophysiology of hepatic Na+/H+ exchange (Review). | 2020 | Details |
| A06824 | 32733933 | Biomed Res Int | Ginsenoside Rb1 Alleviated High-Fat-Diet-Induced Hepatocytic Apoptosis via Peroxisome Proliferator-Activated Receptor γ. | 2020 | Details |
| A06832 | 32730863 | Toxicol In Vitro | Fructose-palmitate based high calorie induce steatosis in HepG2 cells via mitochondrial dysfunction: An in vitro approach. | 2020 | Details |
| A06885 | 32710621 | Nucleic Acids Res | Upregulation of BCL-2 by acridone derivative through gene promoter i-motif for alleviating liver damage of NAFLD/NASH. | 2020 | Details |
| A06913 | 32699233 | Sci Rep | MCD diet-induced steatohepatitis generates a diurnal rhythm of associated biomarkers and worsens liver injury in Klf10 deficient mice. | 2020 | Details |
| A06973 | 32682050 | J Hepatol | Extracellular vesicles as biomarkers in liver diseases: A clinician's point of view. | 2020 | Details |
| A06975 | 32680977 | Aging (Albany NY) | Co-exposure to multi-walled carbon nanotube and lead ions aggravates hepatotoxicity of nonalcoholic fatty liver via inhibiting AMPK/PPARγ pathway. | 2020 | Details |
| A06993 | 32668632 | Int J Mol Sci | Common Drug Pipelines for the Treatment of Diabetic Nephropathy and Hepatopathy: Can We Kill Two Birds with One Stone? | 2020 | Details |
| A07049 | 32642003 | Theranostics | Current understanding of the role of Adipose-derived Extracellular Vesicles in Metabolic Homeostasis and Diseases: Communication from the distance between cells/tissues. | 2020 | Details |
| A07125 | 32613381 | Cell Biol Toxicol | Human hepatic in vitro models reveal distinct anti-NASH potencies of PPAR agonists. | 2020 | Details |
| A07164 | 32595039 | Biochem Biophys Res Commun | Ursodeoxycholic acid alleviates nonalcoholic fatty liver disease by inhibiting apoptosis and improving autophagy via activating AMPK. | 2020 | Details |
| A07202 | 32584509 | Cell Biol Int | NLRC3 silencing accelerates the invasion of hepatocellular carcinoma cell via IL-6/JAK2/STAT3 pathway activation. | 2020 | Details |
| A07228 | 32574416 | Mol Nutr Food Res | Mitochondrial Dysfunction is a Key Pathway that Links Saturated Fat Intake to the Development and Progression of NAFLD. | 2020 | Details |
| A07229 | 32573635 | Food Funct | Studying the effects of sea cucumber ovum powder on nonalcoholic fatty liver disease by proteomics techniques in a rat model. | 2020 | Details |
| A07313 | 32543284 | Expert Opin Pharmacother | Current and emerging pharmacotherapeutic interventions for the treatment of liver fibrosis. | 2020 | Details |
| A07348 | 32529694 | Mol Nutr Food Res | Resveratrol Alleviates Endoplasmic Reticulum Stress-Associated Hepatic Steatosis and Injury in Mice Challenged with Tunicamycin. | 2020 | Details |
| A07356 | 32526845 | Int J Mol Sci | N-Acetylcysteine Reduced Ischemia and Reperfusion Damage Associated with Steatohepatitis in Mice. | 2020 | Details |
| A07359 | 32526787 | Semin Liver Dis | Nonalcoholic Steatohepatitis Promoting Kinases. | 2020 | Details |
| A07397 | 32514497 | JHEP Rep | Combined alcoholic and non-alcoholic steatohepatitis. | 2020 | Details |
| A07409 | 32512191 | Biochim Biophys Acta Mol Basis Dis | Extracellular vesicles derived from fat-laden hepatocytes undergoing chemical hypoxia promote a pro-fibrotic phenotype in hepatic stellate cells. | 2020 | Details |
| A07481 | 32477116 | Front Pharmacol | Herbal Medicine in the Treatment of Non-Alcoholic Fatty Liver Diseases-Efficacy, Action Mechanism, and Clinical Application. | 2020 | Details |
| A07503 | 32470880 | Int Immunopharmacol | Isolation and purification of immune cells from the liver. | 2020 | Details |
| A07504 | 32469428 | Diabetes Metab Res Rev | Adipose tissue remodelling in obese subjects is a determinant of presence and severity of fatty liver disease. | 2020 | Details |
| A07529 | 32454225 | Pharmacol Res | Therapeutic potential of genipin in various acute liver injury, fulminant hepatitis, NAFLD and other non-cancer liver diseases: More friend than foe. | 2020 | Details |
| A07531 | 32454173 | J Ethnopharmacol | An unbiased lipidomics approach identifies key lipid molecules as potential therapeutic targets of Dohongsamul-tang against non-alcoholic fatty liver diseases in a mouse model of obesity. | 2020 | Details |
| A07539 | 32450865 | Lipids Health Dis | Long term N-acetylcysteine administration rescues liver steatosis via endoplasmic reticulum stress with unfolded protein response in mice. | 2020 | Details |
| A07548 | 32446270 | Br J Pharmacol | Astaxanthin attenuates hepatic damage and mitochondrial dysfunction in non-alcoholic fatty liver disease by up-regulating the FGF21/PGC-1α pathway. | 2020 | Details |
| A07559 | 32443660 | Nutrients | Gallic Acid Inhibits Lipid Accumulation via AMPK Pathway and Suppresses Apoptosis and Macrophage-Mediated Inflammation in Hepatocytes. | 2020 | Details |
| A07574 | 32439267 | Clin Nutr | Theaphenon E prevents fatty liver disease and increases CD4+ T cell survival in mice fed a high-fat diet. | 2020 | Details |
| A07600 | 32429478 | Cells | Exogenous Liposomal Ceramide-C6 Ameliorates Lipidomic Profile, Energy Homeostasis, and Anti-Oxidant Systems in NASH. | 2020 | Details |
| A07631 | 32414691 | J Pharmacol Sci | Capsaicinoid nonivamide improves nonalcoholic fatty liver disease in rats fed a high-fat diet. | 2020 | Details |
| A07658 | 32406504 | Biosci Rep | Dysregulation of miR-192-5p in acute pancreatitis patients with nonalcoholic fatty liver and its functional role in acute pancreatitis progression. | 2020 | Details |
| A07662 | 32405180 | J Clin Exp Hepatol | Effect of Donor Hepatic Steatosis on Ischemia Reperfusion Injury in Liver Transplant Recipient. | 2019 | Details |
| A07672 | 32398673 | Nat Commun | Hepatocyte mitochondria-derived danger signals directly activate hepatic stellate cells and drive progression of liver fibrosis. | 2020 | Details |
| A07685 | 32390839 | Front Pharmacol | Hepatoprotective and Anti-Oxidative Effects of Total Flavonoids From Qu Zhi Qiao (Fruit of Citrus Paradisi cv.Changshanhuyou) on Nonalcoholic Steatohepatitis In Vivo and In Vitro Through Nrf2-ARE Signaling Pathway. | 2020 | Details |
| A07699 | 32387461 | J Ethnopharmacol | Ginsenoside Mc1 improves liver steatosis and insulin resistance by attenuating ER stress. | 2020 | Details |
| A07722 | 32376267 | Life Sci | Heme oxygenase-1 alleviated non-alcoholic fatty liver disease via suppressing ROS-dependent endoplasmic reticulum stress. | 2020 | Details |
| A07734 | 32372191 | Dig Dis Sci | G-Protein-Coupled Receptors 120 Agonist III Improves Hepatic Inflammation and ER Stress in Steatohepatitis. | 2020 | Details |
| A07735 | 32371503 | BMJ Open Gastroenterol | SIRT1-dependent mechanisms and effects of resveratrol for amelioration of muscle wasting in NASH mice. | 2020 | Details |
| A07738 | 32369900 | J Clin Med | Inhibition of Protein-tyrosine Phosphatase PTP1B and LMPTP Promotes Palmitate/Oleate-challenged HepG2 Cell Survival by Reducing Lipoapoptosis, Improving Mitochondrial Dynamics and Mitigating Oxidative and Endoplasmic Reticulum Stress. | 2020 | Details |
| A07787 | 32354880 | In Vivo | Pathophysiological Changes During Ischemia-reperfusion Injury in Rodent Hepatic Steatosis. | 2021 | Details |
| A07905 | 32316235 | J Clin Med | The Medium-Chain Fatty Acid Receptor GPR84 Mediates Myeloid Cell Infiltration Promoting Steatohepatitis and Fibrosis. | 2020 | Details |
| A07939 | 32304762 | Life Sci | ApoE deficiency promotes non-alcoholic fatty liver disease in mice via impeding AMPK/mTOR mediated autophagy. | 2020 | Details |
| A07959 | 32298766 | J Hepatol | Lytic cell death in metabolic liver disease. | 2020 | Details |
| A07962 | 32298459 | Histol Histopathol | Comparative analysis of the expression profiles of genes related to the Gadd45α signaling pathway in four kinds of liver diseases. | 2020 | Details |
| A07964 | 32297339 | Hepatology | Milk Fat Globule-Epidermal Growth Factor-Factor 8 Improves Hepatic Steatosis and Inflammation. | 2020 | Details |
| A07985 | 32289885 | Cell Biochem Funct | Retinoic acid induced 16 deficiency exacerbates high-fat diet-induced steatohepatitis in mice. | 2020 | Details |
| A08000 | 32283406 | Environ Pollut | Long-term bisphenol S exposure aggravates non-alcoholic fatty liver by regulating lipid metabolism and inducing endoplasmic reticulum stress response with activation of unfolded protein response in male zebrafish. | 2020 | Details |
| A08008 | 32281248 | Liver Int | Impact of osteopontin on the development of non-alcoholic liver disease and related hepatocellular carcinoma. | 2020 | Details |
| A08062 | 32259637 | Mol Cell Endocrinol | Anti-steatotic linagliptin pleiotropic effects encompasses suppression of de novo lipogenesis and ER stress in high-fat-fed mice. | 2020 | Details |
| A08100 | 32245619 | Biochem Biophys Res Commun | Humanin attenuates palmitate-induced hepatic lipid accumulation and insulin resistance via AMPK-mediated suppression of the mTOR pathway. | 2020 | Details |
| A08114 | 32242391 | J Tradit Chin Med | Sini powder ameliorates the inflammatory response in rats with stress-induced non-alcoholic fatty liver disease by inhibiting the nuclear factor kappa-B / pyrin domain-containing protein 3 pathway. | 2020 | Details |
| A08128 | 32237916 | Expert Opin Pharmacother | Current and new pharmacotherapy options for non-alcoholic steatohepatitis. | 2020 | Details |
| A08166 | 32220583 | J Hepatol | MLKL-dependent signaling regulates autophagic flux in a murine model of non-alcohol-associated fatty liver and steatohepatitis. | 2020 | Details |
| A08188 | 32213662 | Aging (Albany NY) | Role of mitochondrial quality control in the pathogenesis of nonalcoholic fatty liver disease. | 2020 | Details |
| A08195 | 32210914 | Front Endocrinol (Lausanne) | The Atypical Cannabinoid Abn-CBD Reduces Inflammation and Protects Liver, Pancreas, and Adipose Tissue in a Mouse Model of Prediabetes and Non-alcoholic Fatty Liver Disease. | 2020 | Details |
| A08215 | 32200254 | Biomed Pharmacother | Hepalatide ameliorated progression of nonalcoholic steatohepatitis in mice. | 2020 | Details |
| A08223 | 32194141 | Immunol Lett | MiR-149 attenuates endoplasmic reticulum stress-induced inflammation and apoptosis in nonalcoholic fatty liver disease by negatively targeting ATF6 pathway. | 2020 | Details |
| A08228 | 32192487 | Cell Commun Signal | FXR-mediated inhibition of autophagy contributes to FA-induced TG accumulation and accordingly reduces FA-induced lipotoxicity. | 2020 | Details |
| A08262 | 32184095 | Clin Chim Acta | COX-2 in liver fibrosis. | 2020 | Details |