Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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oxidative stress3585 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A02305 | 34427662 | Clin Sci (Lond) | Exposure to cigarette smoke precipitates simple hepatosteatosis to NASH in high-fat diet fed mice by inducing oxidative stress. | 2021 | Details |
| A02312 | 34423525 | Int J Clin Pract | Omega 3-rich Camelina sativa oil in the context of a weight loss program improves glucose homeostasis, inflammation and oxidative stress in patients with NAFLD: A randomised placebo-controlled clinical trial. | 2021 | Details |
| A02329 | 34416350 | Toxicology | Environmental Microcystin exposure in underlying NAFLD-induced exacerbation of neuroinflammation, blood-brain barrier dysfunction, and neurodegeneration are NLRP3 and S100B dependent. | 2021 | Details |
| A02335 | 34414181 | Front Cell Dev Biol | Phytochemicals: Targeting Mitophagy to Treat Metabolic Disorders. | 2021 | Details |
| A02353 | 34406004 | J Agric Food Chem | Baicalein Enhances the Effect of Acarbose on the Improvement of Nonalcoholic Fatty Liver Disease Associated with Prediabetes via the Inhibition of De Novo Lipogenesis. | 2021 | Details |
| A02373 | 34399601 | Int J Immunopathol Pharmacol | Melatonin ameliorates hepatic steatosis by inhibiting NLRP3 inflammasome in db/db mice. | 2022 | Details |
| A02374 | 34399486 | Food Res Int | Protective and ameliorating effects of probiotics against diet-induced obesity: A review. | 2021 | Details |
| A02375 | 34399465 | Food Res Int | Regulatory effects of Lactobacillus fermented black barley on intestinal microbiota of NAFLD rats. | 2021 | Details |
| A02387 | 34393826 | Front Physiol | Similarities and Differences: A Comparative Review of the Molecular Mechanisms and Effectors of NAFLD and AFLD. | 2021 | Details |
| A02393 | 34390493 | Eur J Clin Invest | Mushrooms on the plate: Trends towards NAFLD treatment, health improvement and sustainable diets. | 2021 | Details |
| A02410 | 34383198 | Dig Dis Sci | Environmental Toxicants and NAFLD: A Neglected yet Significant Relationship. | 2021 | Details |
| A02423 | 34375691 | Pharmacol Ther | Xyloketal B: A marine compound with medicinal potential. | 2021 | Details |
| A02467 | 34361619 | Molecules | Antioxidant and Antisteatotic Activities of Fucoidan Fractions from Marine and Terrestrial Sources. | 2021 | Details |
| A02474 | 34360538 | Int J Mol Sci | Diabetes Mellitus and Cardiovascular Diseases: Nutraceutical Interventions Related to Caloric Restriction. | 2021 | Details |
| A02487 | 34356308 | Antioxidants (Basel) | Green Tea and Epigallocatechin Gallate (EGCG) for the Management of Nonalcoholic Fatty Liver Diseases (NAFLD): Insights into the Role of Oxidative Stress and Antioxidant Mechanism. | 2021 | Details |
| A02493 | 34353693 | J Ayurveda Integr Med | Intervention by picroside II on FFAs induced lipid accumulation and lipotoxicity in HepG2 cells. | 2021 | Details |
| A02518 | 34343274 | Endocrinology | SGLT2 Inhibition for Cardiovascular Diseases, Chronic Kidney Disease, and NAFLD. | 2021 | Details |
| A02521 | 34342168 | Physiol Rep | Hormonal regulation of glycine decarboxylase and its relationship to oxidative stress. | 2021 | Details |
| A02522 | 34342164 | Physiol Rep | The effect of endurance training on non-alcoholic fatty liver disease in mice. | 2021 | Details |
| A02529 | 34339945 | Phytomedicine | Investigating the medicinal potential, material basis and mechanism of Polygoni Orientalis Fructus based on multi-technology integrated network pharmacology. | 2021 | Details |
| A02530 | 34339944 | Phytomedicine | Network pharmacology-based identification of significant pathway for protection of Yinhuang granule in a mice model of metabolic-associated fatty liver disease. | 2021 | Details |
| A02533 | 34338703 | Food Funct | Co-supplementation of camelina oil and a prebiotic is more effective for in improving cardiometabolic risk factors and mental health in patients with NAFLD: a randomized clinical trial. | 2021 | Details |
| A02535 | 34337376 | Metabol Open | The role of zinc in the prevention and treatment of nonalcoholic fatty liver disease. | 2021 | Details |
| A02538 | 34335826 | Evid Based Complement Alternat Med | Scolymus hispanicus (Golden Thistle) Ameliorates Hepatic Steatosis and Metabolic Syndrome by Reducing Lipid Accumulation, Oxidative Stress, and Inflammation in Rats under Hyperfatty Diet. | 2021 | Details |
| A02546 | 34332979 | Life Sci | Dimethyl fumarate reduces oxidative stress, inflammation and fat deposition by modulation of Nrf2, SREBP-1c and NF-κB signaling in HFD fed mice. | 2021 | Details |
| A02562 | 34328087 | Biomed Pharmacother | Supplementation of cumin seed powder prevents oxidative stress, hyperlipidemia and non-alcoholic fatty liver in high fat diet fed rats. | 2021 | Details |
| A02594 | 34321089 | Stem Cell Res Ther | Addressing the liver progenitor cell response and hepatic oxidative stress in experimental non-alcoholic fatty liver disease/non-alcoholic steatohepatitis using amniotic epithelial cells. | 2021 | Details |
| A02601 | 34314787 | Adv Drug Deliv Rev | Therapeutic targets, novel drugs, and delivery systems for diabetes associated NAFLD and liver fibrosis. | 2021 | Details |
| A02622 | 34306045 | PPAR Res | Activation of the Peroxisome Proliferator-Activated Receptors (PPAR-α/γ) and the Fatty Acid Metabolizing Enzyme Protein CPT1A by Camel Milk Treatment Counteracts the High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A02623 | 34305621 | Front Pharmacol | Caveolin-1 Alleviates Acetaminophen-Induced Fat Accumulation in Non-Alcoholic Fatty Liver Disease by Enhancing Hepatic Antioxidant Ability via Activating AMPK Pathway. | 2021 | Details |
| A02625 | 34305077 | Exp Anim | AP39 ameliorates high fat diet-induced liver injury in young rats via alleviation of oxidative stress and mitochondrial impairment. | 2021 | Details |
| A02630 | 34303710 | Biochem Pharmacol | Pregnane X receptor exacerbates nonalcoholic fatty liver disease accompanied by obesity- and inflammation-prone gut microbiome signature. | 2021 | Details |
| A02643 | 34298930 | Int J Mol Sci | Upregulation of Anti-Oxidative Stress Response Improves Metabolic Changes in L-Selectin-Deficient Mice but Does Not Prevent NAFLD Progression or Fecal Microbiota Shifts. | 2021 | Details |
| A02662 | 34294375 | J Pharmacol Sci | Ferulic acid attenuates non-alcoholic steatohepatitis by reducing oxidative stress and inflammation through inhibition of the ROCK/NF-κB signaling pathways. | 2021 | Details |
| A02689 | 34281337 | J Agric Food Chem | γ-Linolenic Acid Prevents Lipid Metabolism Disorder in Palmitic Acid-Treated Alpha Mouse Liver-12 Cells by Balancing Autophagy and Apoptosis via the LKB1-AMPK-mTOR Pathway. | 2021 | Details |
| A02692 | 34280515 | Adv Drug Deliv Rev | Pathophysiological communication between hepatocytes and non-parenchymal cells in liver injury from NAFLD to liver fibrosis. | 2021 | Details |
| A02696 | 34279787 | Arch Pharm Res | Aldose Reductase: a cause and a potential target for the treatment of diabetic complications. | 2021 | Details |
| A02704 | 34277668 | Front Med (Lausanne) | Exposure to Plasma From Non-alcoholic Fatty Liver Disease Patients Affects Hepatocyte Viability, Generates Mitochondrial Dysfunction, and Modulates Pathways Involved in Fat Accumulation and Inflammation. | 2021 | Details |
| A02708 | 34277236 | Cureus | The Significance of the Mediterranean Diet in the Management of Non-Alcoholic Fatty Liver Disease: A Systematic Review. | 2021 | Details |
| A02751 | 34260003 | Neurochem Res | Resveratrol Protects SH-SY5Y Cells Against Oleic Acid-Induced Glucolipid Metabolic Dysfunction and Cell Injuries Via the Wnt/β-Catenin Signalling Pathway. | 2021 | Details |
| A02755 | 34257827 | Oxid Med Cell Longev | Changes in Key Mitochondrial Lipids Accompany Mitochondrial Dysfunction and Oxidative Stress in NAFLD. | 2021 | Details |
| A02756 | 34257817 | Oxid Med Cell Longev | The Therapeutic Effects and Mechanisms of Quercetin on Metabolic Diseases: Pharmacological Data and Clinical Evidence. | 2021 | Details |
| A02777 | 34245170 | J Food Biochem | Ziziphus spina-christi (L.) fortified with Camellia sinensis mediates apoptosis, Notch-1 signaling, and mitigates obesity-induced non-alcoholic fatty liver. | 2021 | Details |
| A02787 | 34240649 | Int J Immunopathol Pharmacol | Allopurinol ameliorates liver injury in type 1 diabetic rats through activating Nrf2. | 2022 | Details |
| A02789 | 34239698 | World J Hepatol | Glutathione-S-transferases genes-promising predictors of hepatic dysfunction. | 2021 | Details |
| A02835 | 34225424 | Zhonghua Gan Zang Bing Za Zhi | [Role of gut-liver-immune axis in the pathogenesis of nonalcoholic steatohepatitis]. | 2021 | Details |
| A02883 | 34206404 | Int J Mol Sci | Endothelial Progenitor Cells Dysfunctions and Cardiometabolic Disorders: From Mechanisms to Therapeutic Approaches. | 2021 | Details |
| A02887 | 34204987 | Antioxidants (Basel) | Aqueous Extract of Pepino Leaves Ameliorates Palmitic Acid-Induced Hepatocellular Lipotoxicity via Inhibition of Endoplasmic Reticulum Stress and Apoptosis. | 2021 | Details |
| A02888 | 34204849 | Antioxidants (Basel) | Neonatal Vitamin C and Cysteine Deficiencies Program Adult Hepatic Glutathione and Specific Activities of Glucokinase, Phosphofructokinase, and Acetyl-CoA Carboxylase in Guinea Pigs' Livers. | 2021 | Details |
| A02890 | 34204571 | Biomedicines | The Role of Oxidative Stress in NAFLD-NASH-HCC Transition-Focus on NADPH Oxidases. | 2021 | Details |
| A02895 | 34203484 | Int J Mol Sci | Fructose and the Liver. | 2021 | Details |
| A02904 | 34202179 | Int J Mol Sci | The Alterations of Mitochondrial Function during NAFLD Progression-An Independent Effect of Mitochondrial ROS Production. | 2021 | Details |
| A02905 | 34201527 | Antioxidants (Basel) | Ethyl Acetate Fraction of Amomum villosum var. xanthioides Attenuates Hepatic Endoplasmic Reticulum Stress-Induced Non-Alcoholic Steatohepatitis via Improvement of Antioxidant Capacities. | 2021 | Details |
| A02908 | 34200939 | Foods | Effects of Flutriafol Fungicide on the Lipid Accumulation in Human Liver Cells and Rat Liver. | 2021 | Details |
| A02910 | 34200615 | Nutrients | Lipoic Acid Exacerbates Oxidative Stress and Lipid Accumulation in the Liver of Wistar Rats Fed a Hypercaloric Choline-Deficient Diet. | 2021 | Details |
| A02919 | 34199098 | Int J Mol Sci | Western Diet Decreases the Liver Mitochondrial Oxidative Flux of Succinate: Insight from a Murine NAFLD Model. | 2021 | Details |
| A02924 | 34198236 | Int Immunopharmacol | β-patchoulene protects against non-alcoholic steatohepatitis via interrupting the vicious circle among oxidative stress, histanoxia and lipid accumulation in rats. | 2021 | Details |
| A02932 | 34192596 | Life Sci | Demethylenetetrahydroberberine alleviates nonalcoholic fatty liver disease by inhibiting the NLRP3 inflammasome and oxidative stress in mice. | 2021 | Details |
| A02959 | 34184286 | J Food Biochem | Buchholzia coriacea seed (wonderful kolanut) alleviates insulin resistance, steatosis, inflammation and oxidative stress in high fat diet model of fatty liver disease. | 2021 | Details |
| A02970 | 34179049 | Front Med (Lausanne) | Exploring the Protective Effects and Mechanism of Crocetin From Saffron Against NAFLD by Network Pharmacology and Experimental Validation. | 2021 | Details |
| A02978 | 34176419 | Expert Rev Gastroenterol Hepatol | Chronic liver disease and oxidative stress - a narrative review. | 2021 | Details |
| A02980 | 34175381 | Toxicology | Hepatotoxic potentials of methotrexate: Understanding the possible toxicological molecular mechanisms. | 2021 | Details |
| A02995 | 34171397 | J Ethnopharmacol | Emodin palliates high-fat diet-induced nonalcoholic fatty liver disease in mice via activating the farnesoid X receptor pathway. | 2021 | Details |
| A03024 | 34159911 | Wiad Lek | THE EFFECT OF DOXORUBICIN-INDUCED OXIDATIVE STRESS ON CITRULLINE CONCENTRATION IN THE SMALL INTESTINAL MUCOSA AND PLASMA BLOOD IN RATS WITH NON-ALCOHOLIC STEATOHEPATITIS. | 2021 | Details |
| A03033 | 34156590 | Dig Dis Sci | A Decreased Response to Resistin in Mononuclear Leukocytes Contributes to Oxidative Stress in Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03069 | 34142875 | Crit Rev Food Sci Nutr | Research progress on intervention effect and mechanism of protocatechuic acid on nonalcoholic fatty liver disease. | 2021 | Details |
| A03075 | 34141709 | Front Cell Dev Biol | New Insights Into the Role of Autophagy in Liver Surgery in the Setting of Metabolic Syndrome and Related Diseases. | 2021 | Details |
| A03076 | 34139927 | Pharm Biol | Tocopheryl quinone improves non-alcoholic steatohepatitis (NASH) associated dysmetabolism of glucose and lipids by upregulating the expression of glucagon-like peptide 1 (GLP-1) via restoring the balance of intestinal flora in rats. | 2021 | Details |
| A03087 | 34136174 | Food Sci Nutr | Synergistic effects of black ginseng and aged garlic extracts for the amelioration of nonalcoholic fatty liver disease (NAFLD) in mice. | 2021 | Details |
| A03158 | 34107585 | Zhonghua Gan Zang Bing Za Zhi | [Protective effect of baicalein on high fat-induced hepatocytes oxidative damage]. | 2021 | Details |
| A03162 | 34107274 | Exp Cell Res | Lipid accumulation-induced hepatocyte senescence regulates the activation of hepatic stellate cells through the Nrf2-antioxidant response element pathway. | 2021 | Details |
| A03167 | 34106414 | Cell Biochem Biophys | Thermally Oxidized Coconut Oil as Fat Source in High-Fat Diet Induces Hepatic Fibrosis in Diabetic Rat Model. | 2021 | Details |
| A03173 | 34101924 | Biofactors | alpha-Tocopherol supplementation reduces inflammation and apoptosis in high cholesterol mediated nonalcoholic steatohepatitis. | 2021 | Details |
| A03185 | 34096005 | Methods Mol Biol | Protocols for Mitochondria as the Target of Pharmacological Therapy in the Context of Nonalcoholic Fatty Liver Disease (NAFLD). | 2021 | Details |
| A03248 | 34072586 | Int J Mol Sci | One Week of CDAHFD Induces Steatohepatitis and Mitochondrial Dysfunction with Oxidative Stress in Liver. | 2021 | Details |
| A03253 | 34069635 | Nutrients | Exploratory Data Analysis of Cell and Mitochondrial High-Fat, High-Sugar Toxicity on Human HepG2 Cells. | 2021 | Details |
| A03256 | 34069176 | Life (Basel) | Kaempferol-3-O-Glucuronide Ameliorates Non-Alcoholic Steatohepatitis in High-Cholesterol-Diet-Induced Larval Zebrafish and HepG2 Cell Models via Regulating Oxidation Stress. | 2021 | Details |
| A03259 | 34068699 | J Clin Med | Diabetic Kidney Disease, Cardiovascular Disease and Non-Alcoholic Fatty Liver Disease: A New Triumvirate? | 2021 | Details |
| A03266 | 34065331 | Int J Mol Sci | Nonalcoholic Fatty Liver Disease (NAFLD). Mitochondria as Players and Targets of Therapies? | 2021 | Details |
| A03271 | 34065108 | Int J Mol Sci | Metformin Actions on the Liver: Protection Mechanisms Emerging in Hepatocytes and Immune Cells against NASH-Related HCC. | 2021 | Details |
| A03291 | 34058224 | Metabolism | Regulation of hepatic fibrosis by carcinoembryonic antigen-related cell adhesion molecule 1. | 2021 | Details |
| A03298 | 34055494 | PeerJ | Liver proteome alterations in psychologically distressed rats and a nootropic drug. | 2021 | Details |
| A03307 | 34050922 | Eur J Clin Invest | Mitochondria, oxidative stress and nonalcoholic fatty liver disease: A complex relationship. | 2021 | Details |
| A03316 | 34048566 | J Mol Cell Biol | PSA controls hepatic lipid metabolism by regulating the NRF2 signaling pathway. | 2021 | Details |
| A03327 | 34043417 | Circ Res | Nonalcoholic Fatty Liver Disease: An Emerging Driver of Cardiac Arrhythmia. | 2021 | Details |
| A03332 | 34040583 | Front Endocrinol (Lausanne) | Gene-Environmental Interactions as Metabolic Drivers of Nonalcoholic Steatohepatitis. | 2021 | Details |
| A03351 | 34031913 | J Gastroenterol Hepatol | TA allele of rs2070673 in the CYP2E1 gene is associated with lobular inflammation and nonalcoholic steatohepatitis in patients with biopsy-proven nonalcoholic fatty liver disease. | 2021 | Details |
| A03372 | 34027109 | Clin Exp Hepatol | Non-alcoholic fatty liver disease and lipotoxicity. | 2021 | Details |
| A03375 | 34025683 | Front Immunol | Nutrigenetic Interactions Might Modulate the Antioxidant and Anti-Inflammatory Status in Mastiha-Supplemented Patients With NAFLD. | 2021 | Details |
| A03405 | 34014044 | Pharmacol Res Perspect | Modulation of vascular contraction via soluble guanylate cyclase signaling in a novel ex vivo method using rat precision-cut liver slices. | 2021 | Details |
| A03418 | 34007294 | Evid Based Complement Alternat Med | Mechanism of Huo-Xue-Qu-Yu Formula in Treating Nonalcoholic Hepatic Steatosis by Regulating Lipid Metabolism and Oxidative Stress in Rats. | 2021 | Details |
| A03452 | 33994867 | Int J Biol Sci | MicroRNAs in the Pathogenesis of Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03461 | 33992698 | J Hepatol | Molecular characterisation of hepatocellular carcinoma in patients with non-alcoholic steatohepatitis. | 2021 | Details |
| A03472 | 33991395 | Chem Biodivers | The Therapeutic Effects and Mechanisms of Salidroside on Cardiovascular and Metabolic Diseases: An Updated Review. | 2021 | Details |
| A03474 | 33990765 | Acta Pharmacol Sin | Blueberry-derived exosomes-like nanoparticles ameliorate nonalcoholic fatty liver disease by attenuating mitochondrial oxidative stress. | 2021 | Details |
| A03507 | 33977953 | Food Funct | Hesperetin ameliorates hepatic oxidative stress and inflammation via the PI3K/AKT-Nrf2-ARE pathway in oleic acid-induced HepG2 cells and a rat model of high-fat diet-induced NAFLD. | 2021 | Details |
| A03508 | 33977946 | Food Funct | DHA-enriched phosphatidylserine ameliorates non-alcoholic fatty liver disease and intestinal dysbacteriosis in mice induced by a high-fat diet. | 2021 | Details |
| A03511 | 33975804 | Trends Endocrinol Metab | Links between metabolic syndrome and metabolic dysfunction-associated fatty liver disease. | 2021 | Details |
| A03513 | 33974978 | Free Radic Biol Med | Effects of astaxanthin in animal models of obesity-associated diseases: A systematic review and meta-analysis. | 2021 | Details |
| A03531 | 33966916 | Arch Med Res | Hepatic Accumulation of Hypoxanthine: A Link Between Hyperuricemia and Nonalcoholic Fatty Liver Disease. | 2021 | Details |