Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A19238 | 26679056 | Mol Nutr Food Res | Green tea extract provides extensive Nrf2-independent protection against lipid accumulation and NFκB pro- inflammatory responses during nonalcoholic steatohepatitis in mice fed a high-fat diet. | 2016 | Details |
| A19249 | 26674248 | BBA Clin | Mechanism of the development of nonalcoholic steatohepatitis after pancreaticoduodenectomy. | 2015 | Details |
| A19256 | 26670487 | Am J Physiol Endocrinol Metab | Metabolic phenotype and adipose and liver features in a high-fat Western diet-induced mouse model of obesity-linked NAFLD. | 2015 | Details |
| A19259 | 26668692 | World J Hepatol | Bile acid receptors and nonalcoholic fatty liver disease. | 2015 | Details |
| A19260 | 26668503 | World J Gastroenterol | Peroxisome proliferator-activated receptor-delta agonist ameliorated inflammasome activation in nonalcoholic fatty liver disease. | 2015 | Details |
| A19274 | 26663010 | Hepatobiliary Pancreat Dis Int | Ankaflavin ameliorates steatotic liver ischemia-reperfusion injury in mice. | 2015 | Details |
| A19275 | 26663004 | Hepatobiliary Pancreat Dis Int | Gut microbiota and non-alcoholic fatty liver disease. | 2015 | Details |
| A19276 | 26662852 | Hepatology | NKp46(+) natural killer cells attenuate metabolism-induced hepatic fibrosis by regulating macrophage activation in mice. | 2016 | Details |
| A19279 | 26657927 | Minerva Gastroenterol Dietol | Probiotics in digestive diseases: focus on Lactobacillus GG. | 2015 | Details |
| A19287 | 26650570 | Endocrinology | Hepatocyte-Specific Disruption of CD36 Attenuates Fatty Liver and Improves Insulin Sensitivity in HFD-Fed Mice. | 2015 | Details |
| A19291 | 26646450 | Oncotarget | Activation of an endothelial Notch1-Jagged1 circuit induces VCAM1 expression, an effect amplified by interleukin-1β. | 2015 | Details |
| A19292 | 26645107 | J Cell Mol Med | Role of stem cells during diabetic liver injury. | 2015 | Details |
| A19310 | 26635079 | BMC Gastroenterol | Gut microbiota manipulation with prebiotics in patients with non-alcoholic fatty liver disease: a randomized controlled trial protocol. | 2015 | Details |
| A19312 | 26634892 | Phytother Res | Gastrodin Ameliorates Oxidative Stress and Proinflammatory Response in Nonalcoholic Fatty Liver Disease through the AMPK/Nrf2 Pathway. | 2015 | Details |
| A19316 | 26633474 | Nutrients | The Emerging Role of Disturbed CoQ Metabolism in Nonalcoholic Fatty Liver Disease Development and Progression. | 2015 | Details |
| A19322 | 26629827 | PLoS One | Hyperreactivity of Blood Leukocytes in Patients with NAFLD to Ex Vivo Lipopolysaccharide Treatment Is Modulated by Metformin and Phosphatidylcholine but Not by Alpha Ketoglutarate. | 2015 | Details |
| A19336 | 26621917 | J Lipid Res | Hepatocytes release ceramide-enriched pro-inflammatory extracellular vesicles in an IRE1α-dependent manner. | 2015 | Details |
| A19338 | 26621325 | J Diabetes | Soluble epoxide hydrolase: A potential target for metabolic diseases. | 2016 | Details |
| A19345 | 26618774 | PLoS One | A Prospective Study of Fatty Liver Index and Incident Hypertension: The KoGES-ARIRANG Study. | 2015 | Details |
| A19352 | 26612838 | Toxicol Sci | Polychlorinated Biphenyl-Xenobiotic Nuclear Receptor Interactions Regulate Energy Metabolism, Behavior, and Inflammation in Non-alcoholic-Steatohepatitis. | 2015 | Details |
| A19356 | 26609894 | Expert Opin Ther Targets | Pathophysiological mechanisms and therapeutic potentials of macrophages in non-alcoholic steatohepatitis. | 2016 | Details |
| A19358 | 26608915 | J Immunol | S100A8 Production in CXCR2-Expressing CD11b+Gr-1high Cells Aggravates Hepatitis in Mice Fed a High-Fat and High-Cholesterol Diet. | 2015 | Details |
| A19364 | 26603137 | Am J Pathol | Diet-Induced Obesity Enhances Progression of Hepatocellular Carcinoma through Tenascin-C/Toll-Like Receptor 4 Signaling. | 2015 | Details |
| A19374 | 26600310 | J Cell Biochem | Dietary Saturated Fat Promotes Development of Hepatic Inflammation Through Toll-Like Receptor 4 in Mice. | 2015 | Details |
| A19378 | 26599575 | PLoS One | Peripheral and Hepatic Vein Cytokine Levels in Correlation with Non-Alcoholic Fatty Liver Disease (NAFLD)-Related Metabolic, Histological, and Haemodynamic Features. | 2015 | Details |
| A19384 | 26597657 | Obes Rev | Association of recently described adipokines with liver histology in biopsy-proven non-alcoholic fatty liver disease: a systematic review. | 2015 | Details |
| A19388 | 26594248 | Diabetol Metab Syndr | Treatment with the SGLT2 inhibitor luseogliflozin improves nonalcoholic steatohepatitis in a rodent model with diabetes mellitus. | 2015 | Details |
| A19390 | 26593707 | Eur J Pharmacol | Betaine prevented fructose-induced NAFLD by regulating LXRα/PPARα pathway and alleviating ER stress in rats. | 2015 | Details |
| A19398 | 26592314 | Proc Nutr Soc | Polyphenols and non-alcoholic fatty liver disease: impact and mechanisms. | 2015 | Details |
| A19425 | 26573228 | Oncotarget | LPS-induced TNF-α factor mediates pro-inflammatory and pro-fibrogenic pattern in non-alcoholic fatty liver disease. | 2015 | Details |
| A19429 | 26572131 | J Biomed Sci | Caffeine reduces hepatic lipid accumulation through regulation of lipogenesis and ER stress in zebrafish larvae. | 2015 | Details |
| A19437 | 26569269 | Mar Drugs | Polyphenol-Rich Fraction of Ecklonia cava Improves Nonalcoholic Fatty Liver Disease in High Fat Diet-Fed Mice. | 2015 | Details |
| A19441 | 26567565 | Biochemistry (Mosc) | Molecular Mechanisms of Latent Inflammation in Metabolic Syndrome. Possible Role of Sirtuins and Peroxisome Proliferator-Activated Receptor Type γ. | 2015 | Details |
| A19450 | 26564718 | Am J Physiol Gastrointest Liver Physiol | Podoplanin discriminates distinct stromal cell populations and a novel progenitor subset in the liver. | 2015 | Details |
| A19451 | 26564716 | Am J Physiol Gastrointest Liver Physiol | Iron overload results in hepatic oxidative stress, immune cell activation, and hepatocellular ballooning injury, leading to nonalcoholic steatohepatitis in genetically obese mice. | 2015 | Details |
| A19454 | 26560698 | J Exp Clin Cancer Res | Tumor progression locus 2 ablation suppressed hepatocellular carcinoma development by inhibiting hepatic inflammation and steatosis in mice. | 2015 | Details |
| A19457 | 26557974 | Iran J Basic Med Sci | Effect of pioglitazone, quercetin and hydroxy citric acid on extracellular matrix components in experimentally induced non-alcoholic steatohepatitis. | 2015 | Details |
| A19459 | 26557952 | World J Hepatol | Dietary supplements and pediatric non-alcoholic fatty liver disease: Present and the future. | 2015 | Details |
| A19461 | 26556986 | World J Gastroenterol | Genetic, metabolic and environmental factors involved in the development of liver cirrhosis in Mexico. | 2015 | Details |
| A19487 | 26525891 | Sci Rep | Inhibition of HMGB1 release via salvianolic acid B-mediated SIRT1 up-regulation protects rats against non-alcoholic fatty liver disease. | 2015 | Details |
| A19490 | 26524607 | Scand J Immunol | Effect of Lipopolysaccharide on the Progression of Non-Alcoholic Fatty Liver Disease in High Caloric Diet-Fed Mice. | 2016 | Details |
| A19493 | 26524133 | Expert Rev Gastroenterol Hepatol | The role of chronic inflammation in the development of gastrointestinal cancers: reviewing cancer prevention with natural anti-inflammatory intervention. | 2015 | Details |
| A19494 | 26523207 | World J Hepatol | Role of pentoxifylline in non-alcoholic fatty liver disease in high-fat diet-induced obesity in mice. | 2015 | Details |
| A19501 | 26518899 | Cell Mol Biol (Noisy-le-grand) | Saturated fatty acid induces cancer stem cell-like properties in human hepatoma cells. | 2015 | Details |
| A19533 | 26506376 | Nutrients | The Ethanol Extract from Lonicera japonica Thunb. Regresses Nonalcoholic Steatohepatitis in a Methionine- and Choline-Deficient Diet-Fed Animal Model. | 2015 | Details |
| A19536 | 26503843 | Liver Int | The effects of DASH diet on weight loss and metabolic status in adults with non-alcoholic fatty liver disease: a randomized clinical trial. | 2015 | Details |
| A19538 | 26502288 | Gynecol Endocrinol | Visceral adiposity index as a predictor of clinical severity and therapeutic outcome of PCOS. | 2015 | Details |
| A19542 | 26499443 | Int J Obes (Lond) | Surgical removal of inflamed epididymal white adipose tissue attenuates the development of non-alcoholic steatohepatitis in obesity. | 2015 | Details |
| A19543 | 26498332 | Lipids Health Dis | Resveratrol ameliorates hepatic steatosis and inflammation in methionine/choline-deficient diet-induced steatohepatitis through regulating autophagy. | 2015 | Details |
| A19544 | 26498267 | Environ Toxicol Pharmacol | Fucoidan ameliorates steatohepatitis and insulin resistance by suppressing oxidative stress and inflammatory cytokines in experimental non-alcoholic fatty liver disease. | 2015 | Details |
| A19550 | 26494227 | Carcinogenesis | Connexin 32 and luteolin play protective roles in non-alcoholic steatohepatitis development and its related hepatocarcinogenesis in rats. | 2015 | Details |
| A19551 | 26494024 | Nutr Res Rev | Murine models provide insight to the development of non-alcoholic fatty liver disease. | 2015 | Details |
| A19553 | 26491664 | Biomed Res Int | The Crosstalk between Hypoxia and Innate Immunity in the Development of Obesity-Related Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19555 | 26487938 | J Gastrointest Oncol | Increased risk of colorectal polyps in patients with non-alcoholic fatty liver disease undergoing liver transplant evaluation. | 2015 | Details |
| A19566 | 26482537 | J Lipid Res | SphK1 mediates hepatic inflammation in a mouse model of NASH induced by high saturated fat feeding and initiates proinflammatory signaling in hepatocytes. | 2015 | Details |
| A19568 | 26477387 | Pharmacol Res | Cyanidin 3-glucoside improves diet-induced metabolic syndrome in rats. | 2015 | Details |
| A19580 | 26473743 | Hepatology | Inhibition of hedgehog signaling ameliorates hepatic inflammation in mice with nonalcoholic fatty liver disease. | 2015 | Details |
| A19587 | 26472223 | Am J Physiol Gastrointest Liver Physiol | Hepatocyte X-box binding protein 1 deficiency increases liver injury in mice fed a high-fat/sugar diet. | 2015 | Details |
| A19589 | 26471014 | Food Funct | Anti-steatotic effects of an n-3 LCPUFA and extra virgin olive oil mixture in the liver of mice subjected to high-fat diet. | 2016 | Details |
| A19590 | 26469357 | Eur J Gastroenterol Hepatol | A novel model using mean platelet volume and neutrophil to lymphocyte ratio as a marker of nonalcoholic steatohepatitis in NAFLD patients: multicentric study. | 2016 | Details |
| A19594 | 26464753 | World J Hepatol | Pathogenesis of hepatocarcinogenesis in non-cirrhotic nonalcoholic fatty liver disease: Potential mechanistic pathways. | 2015 | Details |
| A19603 | 26462272 | BMJ Open Gastroenterol | Systematic review of genetic association studies involving histologically confirmed non-alcoholic fatty liver disease. | 2015 | Details |
| A19613 | 26457019 | World J Gastroenterol | Does herbal medicine reduce the risk of hepatocellular carcinoma? | 2015 | Details |
| A19622 | 26450277 | Br J Nutr | Supplementation of sodium butyrate protects mice from the development of non-alcoholic steatohepatitis (NASH). | 2015 | Details |
| A19625 | 26449539 | BMC Genomics | The impact of PPARα activation on whole genome gene expression in human precision cut liver slices. | 2015 | Details |
| A19629 | 26447961 | J Clin Gastroenterol | Probiotics in Nonalcoholic Fatty Liver Disease, Nonalcoholic Steatohepatitis, and Cirrhosis. | 2016 | Details |
| A19632 | 26447219 | Am J Physiol Renal Physiol | NKT cell modulates NAFLD potentiation of metabolic oxidative stress-induced mesangial cell activation and proximal tubular toxicity. | 2015 | Details |
| A19655 | 26435020 | Bratisl Lek Listy | Petroselinum crispum extract attenuates hepatic steatosis in rats fed with fructose enriched diet. | 2015 | Details |
| A19659 | 26431876 | Biochem Biophys Res Commun | Hepatic scavenger receptor BI is associated with type 2 diabetes but unrelated to human and murine non-alcoholic fatty liver disease. | 2015 | Details |
| A19660 | 26430826 | J Am Coll Nutr | Effects of Multistrain Probiotic Supplementation on Glycemic and Inflammatory Indices in Patients with Nonalcoholic Fatty Liver Disease: A Double-Blind Randomized Clinical Trial. | 2015 | Details |
| A19685 | 26411937 | Nihon Eiseigaku Zasshi | [Mechanism Analysis and Prevention of Pathogenesis of Nonalcoholic Steatohepatitis]. | 2015 | Details |
| A19689 | 26408952 | Prostaglandins Other Lipid Mediat | Metabolites of arachidonic acid and linoleic acid in early stages of non-alcoholic fatty liver disease--A pilot study. | 2015 | Details |
| A19692 | 26407654 | Eur J Pharmacol | Perindopril and barnidipine alone or combined with simvastatin on hepatic steatosis and inflammatory parameters in hypertensive patients. | 2015 | Details |
| A19696 | 26405765 | PLoS One | Replacement of Dietary Saturated Fat by PUFA-Rich Pumpkin Seed Oil Attenuates Non-Alcoholic Fatty Liver Disease and Atherosclerosis Development, with Additional Health Effects of Virgin over Refined Oil. | 2015 | Details |
| A19700 | 26405687 | Cell Mol Gastroenterol Hepatol | Hepatic Injury in Nonalcoholic Steatohepatitis Contributes to Altered Intestinal Permeability. | 2015 | Details |
| A19715 | 26397391 | Mol Med Rep | Treatment of experimental non-alcoholic steatohepatitis by targeting α7 nicotinic acetylcholine receptor-mediated inflammatory responses in mice. | 2015 | Details |
| A19719 | 26395746 | Int J Obes (Lond) | A novel cobiotic-based preventive approach against high-fat diet-induced adiposity, nonalcoholic fatty liver and gut derangement in mice. | 2015 | Details |
| A19726 | 26394162 | J Hepatol | CXC chemokine receptor 3 promotes steatohepatitis in mice through mediating inflammatory cytokines, macrophages and autophagy. | 2015 | Details |
| A19729 | 26391864 | J Nutr Biochem | Dietary cholesterol induces hepatic inflammation and blunts mitochondrial function in the liver of high-fat-fed mice. | 2015 | Details |
| A19740 | 26380042 | World J Hepatol | Targeting Kupffer cells in non-alcoholic fatty liver disease/non-alcoholic steatohepatitis: Why and how? | 2015 | Details |
| A19741 | 26379885 | Int J Clin Exp Med | Physical training improves body weight and energy balance but does not protect against hepatic steatosis in obese mice. | 2015 | Details |
| A19744 | 26378649 | Semin Liver Dis | The Evolving Role of Nonalcoholic Fatty Liver Disease in Hepatic Neoplasia: Inflammatory Hepatocellular Adenoma in a Man with Metabolic Syndrome. | 2015 | Details |
| A19752 | 26378641 | Semin Liver Dis | Systemic Complications of Nonalcoholic Fatty Liver Disease: When the Liver Is Not an Innocent Bystander. | 2015 | Details |
| A19779 | 26355465 | Inflamm Bowel Dis | PNPLA3 148M Carriers with Inflammatory Bowel Diseases Have Higher Susceptibility to Hepatic Steatosis and Higher Liver Enzymes. | 2016 | Details |
| A19781 | 26355033 | Sci Transl Med | Excessive caloric intake acutely causes oxidative stress, GLUT4 carbonylation, and insulin resistance in healthy men. | 2015 | Details |
| A19805 | 26339640 | Biomed Res Int | The Role of Dendritic Cells in Fibrosis Progression in Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A19807 | 26338827 | Gut | Liver microRNA-21 is overexpressed in non-alcoholic steatohepatitis and contributes to the disease in experimental models by inhibiting PPARα expression. | 2015 | Details |
| A19808 | 26338727 | Gut | The gut microbiota and host health: a new clinical frontier. | 2015 | Details |
| A19809 | 26337107 | Curr Med Chem | Emerging Vascular Risk Factors in Women: Any Differences from Men? | 2015 | Details |
| A19820 | 26328025 | World J Hepatol | From the stomach to other organs: Helicobacter pylori and the liver. | 2015 | Details |
| A19826 | 26323153 | Zhongguo Zhong Yao Za Zhi | [Experimental study on intervention effect of Grifola frondosa on nonalcoholic steatohepatitis]. | 2015 | Details |
| A19831 | 26318867 | Transl Res | Targeting gut-liver axis for the treatment of nonalcoholic steatohepatitis: translational and clinical evidence. | 2015 | Details |
| A19834 | 26316717 | Drug Des Devel Ther | Nonalcoholic steatohepatitis: emerging targeted therapies to optimize treatment options. | 2015 | Details |
| A19838 | 26315841 | Int J Obes (Lond) | Exogenous administration of DLK1 ameliorates hepatic steatosis and regulates gluconeogenesis via activation of AMPK. | 2015 | Details |
| A19852 | 26305052 | Biochem Cell Biol | Proposed trial: safety and efficacy of resveratrol for the treatment of non-alcoholic fatty liver disease (NAFLD) and associated insulin resistance in adolescents who are overweight or obese adolescents - rationale and protocol. | 2015 | Details |
| A19860 | 26300331 | J Nutr Biochem | Decaffeinated green tea extract rich in epigallocatechin-3-gallate prevents fatty liver disease by increased activities of mitochondrial respiratory chain complexes in diet-induced obesity mice. | 2015 | Details |
| A19865 | 26298775 | Sleep Med | Evaluation of circulating markers of hepatic apoptosis and inflammation in obese children with and without obstructive sleep apnea. | 2015 | Details |
| A19867 | 26297911 | Biochem Pharmacol | A dipeptidyl peptidase-IV inhibitor improves hepatic steatosis and insulin resistance by AMPK-dependent and JNK-dependent inhibition of LECT2 expression. | 2015 | Details |
| A19872 | 26292849 | Br J Pharmacol | Salsalate attenuates diet induced non-alcoholic steatohepatitis in mice by decreasing lipogenic and inflammatory processes. | 2015 | Details |
| A19878 | 26289505 | Niger J Clin Pract | Nonalcoholic fatty liver disease: Synopsis of current developments. | 2016 | Details |