Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
Article ID | PMID | Source | Title | Publish Year | |
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A14727 | 29269727 | Nat Commun | Pro-inflammatory hepatic macrophages generate ROS through NADPH oxidase 2 via endocytosis of monomeric TLR4-MD2 complex. | 2017 | Details |
A14730 | 29268121 | J Nutr Biochem | Age-dependent alterations of glucose clearance and homeostasis are temporally separated and modulated by dietary fat. | 2017 | Details |
A14732 | 29266821 | J Diabetes Investig | Angiopoietin-like protein 8/betatrophin correlates with hepatocellular lipid content independent of insulin resistance in non-alcoholic fatty liver disease patients. | 2018 | Details |
A14736 | 29266009 | Curr Opin Gastroenterol | Nonalcoholic fatty liver disease, cholesterol gallstones, and cholecystectomy: new insights on a complex relationship. | 2018 | Details |
A14739 | 29264555 | J Endocr Soc | Nonalcoholic Fatty Liver Disease in Hispanic Youth With Dysglycemia: Risk for Subclinical Atherosclerosis? | 2017 | Details |
A14741 | 29263303 | JCI Insight | Intestinal, but not hepatic, ChREBP is required for fructose tolerance. | 2017 | Details |
A14742 | 29263118 | Physiol Rep | In vitro cellular models of human hepatic fatty acid metabolism: differences between Huh7 and HepG2 cell lines in human and fetal bovine culturing serum. | 2017 | Details |
A14743 | 29262266 | Appl Physiol Nutr Metab | Effect of a short-term physical activity intervention on liver fat content in obese children. | 2017 | Details |
A14751 | 29255346 | Drug Des Devel Ther | Hepatoprotective effect of calculus bovis sativus on nonalcoholic fatty liver disease in mice by inhibiting oxidative stress and apoptosis of hepatocytes. | 2017 | Details |
A14757 | 29253490 | Metabolism | Restricted feeding for 9h in the active period partially abrogates the detrimental metabolic effects of a Western diet with liquid sugar consumption in mice. | 2017 | Details |
A14761 | 29249967 | Front Pharmacol | Psoralea corylifolia L. Attenuates Nonalcoholic Steatohepatitis in Juvenile Mouse. | 2017 | Details |
A14780 | 29235656 | Br J Dermatol | Nonalcoholic fatty liver disease in patients with psoriasis: a consequence of systemic inflammatory burden? | 2018 | Details |
A14782 | 29235014 | Obes Surg | Increased Bile Acid Signals After Duodenal-Jejunal Bypass Improve Non-alcoholic Steatohepatitis (NASH) in a Rodent Model of Diet-Induced NASH. | 2018 | Details |
A14785 | 29234288 | Front Physiol | Lipocalin-2 in Fructose-Induced Fatty Liver Disease. | 2017 | Details |
A14791 | 29231919 | Pol Merkur Lekarski | [Non-alcoholic liver disease - diagnosis and treatment]. | 2017 | Details |
A14796 | 29227477 | Nat Med | The deubiquitinating enzyme TNFAIP3 mediates inactivation of hepatic ASK1 and ameliorates nonalcoholic steatohepatitis. | 2017 | Details |
A14799 | 29226105 | J Clin Transl Hepatol | Non-alcoholic Fatty Liver Disease: A Clinical Update. | 2017 | Details |
A14801 | 29225114 | Prog Cardiovasc Dis | Fructose-induced inflammation and increased cortisol: A new mechanism for how sugar induces visceral adiposity. | 2017 | Details |
A14804 | 29224108 | Adv Exp Med Biol | Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men. | 2017 | Details |
A14805 | 29224098 | Adv Exp Med Biol | Role of Estrogens in the Regulation of Liver Lipid Metabolism. | 2017 | Details |
A14808 | 29223443 | Clin Gastroenterol Hepatol | Response to Pioglitazone in Patients With Nonalcoholic Steatohepatitis With vs Without Type 2 Diabetes. | 2017 | Details |
A14816 | 29222051 | Biochem Biophys Res Commun | Long-term fermented soybean paste improves metabolic parameters associated with non-alcoholic fatty liver disease and insulin resistance in high-fat diet-induced obese mice. | 2017 | Details |
A14818 | 29221790 | Metabolism | FAM3 gene family: A promising therapeutical target for NAFLD and type 2 diabetes. | 2017 | Details |
A14832 | 29214926 | Nutr Health | Aerobic training performed at ventilatory threshold improves liver enzymes and lipid profile related to non-alcoholic fatty liver disease in adolescents with obesity. | 2017 | Details |
A14834 | 29212576 | Gene Expr | The Effects of Physical Exercise on Fatty Liver Disease. | 2017 | Details |
A14839 | 29209995 | Diabetes Ther | Early Clinical Expressions of Insulin Resistance: The Real Enemy to Look For. | 2017 | Details |
A14840 | 29209440 | EPMA J | Efficacy of Fenugreek-based bionanocomposite on renal dysfunction and endogenous intoxication in high-calorie diet-induced obesity rat model-comparative study. | 2017 | Details |
A14845 | 29207650 | Oncotarget | Upregulation of miR-181a impairs hepatic glucose and lipid homeostasis. | 2017 | Details |
A14849 | 29204141 | Front Microbiol | Flos Lonicera Combined with Metformin Ameliorates Hepatosteatosis and Glucose Intolerance in Association with Gut Microbiota Modulation. | 2017 | Details |
A14850 | 29204050 | World J Gastroenterol | Current and emerging pharmacological therapy for non-alcoholic fatty liver disease. | 2017 | Details |
A14851 | 29203714 | Philos Trans R Soc Lond B Biol Sci | Exercise, heat shock proteins and insulin resistance. | 2018 | Details |
A14852 | 29203511 | Diabetes | Adipocyte JAK2 Regulates Hepatic Insulin Sensitivity Independently of Body Composition, Liver Lipid Content, and Hepatic Insulin Signaling. | 2017 | Details |
A14859 | 29201794 | Euroasian J Hepatogastroenterol | Role of Probiotics in the Treatment of Nonalcoholic Fatty Liver Disease: A Meta-analysis. | 2017 | Details |
A14861 | 29201200 | Exp Ther Med | Effect of a stilbene glycoside-rich extract from Polygoni Multiflori Radix on experimental non-alcoholic fatty liver disease based on principal component and orthogonal partial least squares discriminant analysis. | 2017 | Details |
A14867 | 29199410 | Diabetes Metab J | Non-Alcoholic Fatty Liver Disease: The Emerging Burden in Cardiometabolic and Renal Diseases. | 2017 | Details |
A14870 | 29197664 | Biochim Biophys Acta Mol Basis Dis | Emerging metabolic risk factors in hepatocellular carcinoma and their influence on the liver microenvironment. | 2017 | Details |
A14871 | 29197627 | Int J Biochem Cell Biol | MiR-34a regulates mitochondrial content and fat ectopic deposition induced by resistin through the AMPK/PPARα pathway in HepG2 cells. | 2017 | Details |
A14875 | 29197188 | FEBS J | Genipin alleviates high-fat diet-induced hyperlipidemia and hepatic lipid accumulation in mice via miR-142a-5p/SREBP-1c axis. | 2017 | Details |
A14877 | 29194974 | J Diabetes | Serum fetuin-B is positively associated with intrahepatic triglyceride content and increases the risk of insulin resistance in obese Chinese adults: A cross-sectional study. | 2018 | Details |
A14883 | 29193269 | J Gastroenterol Hepatol | Additive effects of PNPLA3 and TM6SF2 on the histological severity of non-alcoholic fatty liver disease. | 2018 | Details |
A14887 | 29190550 | J Nutr Biochem | Green tea extract protects against hepatic NFκB activation along the gut-liver axis in diet-induced obese mice with nonalcoholic steatohepatitis by reducing endotoxin and TLR4/MyD88 signaling. | 2017 | Details |
A14891 | 29189176 | Rev Recent Clin Trials | The Emerging Role of Complement C3 as A Biomarker of Insulin Resistance and Cardiometabolic Diseases: Preclinical and Clinical Evidence. | 2018 | Details |
A14892 | 29189132 | Curr Pharm Des | Polyphenols: Novel Signaling Pathways. | 2018 | Details |
A14893 | 29188065 | BMJ Open Diabetes Res Care | High circulating plasma dipeptidyl peptidase- 4 levels in non-obese Asian Indians with type 2 diabetes correlate with fasting insulin and LDL-C levels, triceps skinfolds, total intra-abdominal adipose tissue volume and presence of diabetes: a case-control study. | 2017 | Details |
A14895 | 29187144 | BMC Gastroenterol | Non-alcoholic fatty liver disease and its associations among adolescents in an urban, Sri Lankan community. | 2017 | Details |
A14901 | 29183220 | Phys Sportsmed | The effect of low volume sprint interval training in patients with non-alcoholic fatty liver disease. | 2017 | Details |
A14907 | 29179679 | BMC Gastroenterol | Attenuating the rate of total body fat accumulation and alleviating liver damage by oral administration of vitamin D-enriched edible mushrooms in a diet-induced obesity murine model is mediated by an anti-inflammatory paradigm shift. | 2017 | Details |
A14916 | 29175242 | J Hepatol | Association of non-alcoholic steatohepatitis with subclinical myocardial dysfunction in non-cirrhotic patients. | 2017 | Details |
A14933 | 29167318 | Clin Sci (Lond) | TRAIL reduces impaired glucose tolerance and NAFLD in the high-fat diet fed mouse. | 2018 | Details |
A14935 | 29167192 | J Investig Med | Cytokeratin-18 and enhanced liver fibrosis scores in type 1 and type 2 diabetes and effects of two different insulins. | 2017 | Details |
A14942 | 29163785 | Oncotarget | TM5441, a plasminogen activator inhibitor-1 inhibitor, protects against high fat diet-induced non-alcoholic fatty liver disease. | 2017 | Details |
A14943 | 29162875 | Sci Rep | Effect of aerobic exercise and diet on liver fat in pre-diabetic patients with non-alcoholic-fatty-liver-disease: A randomized controlled trial. | 2017 | Details |
A14944 | 29162773 | J Atheroscler Thromb | A High-Fat and High-Cholesterol Diet Induces Cardiac Fibrosis, Vascular Endothelial, and Left Ventricular Diastolic Dysfunction in SHRSP5/Dmcr Rats. | 2017 | Details |
A14946 | 29161258 | PLoS One | Insulin resistance and hyperandrogenism drive steatosis and fibrosis risk in young females with PCOS. | 2017 | Details |
A14947 | 29161233 | J Basic Clin Physiol Pharmacol | Swimming, but not vitamin E, ameliorates prothrombotic state and hypofibrinolysis in a rat model of nonalcoholic fatty liver disease. | 2018 | Details |
A14948 | 29160087 | Antioxid Redox Signal | Glyoxalase 1 Modulation in Obesity and Diabetes. | 2018 | Details |
A14949 | 29159396 | JAMA Neurol | Association of Nonalcoholic Fatty Liver Disease With Lower Brain Volume in Healthy Middle-aged Adults in the Framingham Study. | 2018 | Details |
A14953 | 29158183 | Biochim Biophys Acta Mol Basis Dis | Serine prevented high-fat diet-induced oxidative stress by activating AMPK and epigenetically modulating the expression of glutathione synthesis-related genes. | 2017 | Details |
A14957 | 29156529 | Biomed Pharmacother | Alpinetin improved high fat diet-induced non-alcoholic fatty liver disease (NAFLD) through improving oxidative stress, inflammatory response and lipid metabolism. | 2017 | Details |
A14958 | 29156528 | Biomed Pharmacother | Actein ameliorates hepatic steatosis and fibrosis in high fat diet-induced NAFLD by regulation of insulin and leptin resistant. | 2017 | Details |
A14960 | 29155143 | Eur J Pharmacol | Obeticholic acid raises LDL-cholesterol and reduces HDL-cholesterol in the Diet-Induced NASH (DIN) hamster model. | 2017 | Details |
A14964 | 29154469 | Pathol Int | Novel non-alcoholic steatohepatitis model with histopathological and insulin-resistant features. | 2017 | Details |
A14969 | 29151428 | J Clin Sleep Med | Continuous Positive Airway Pressure in Patients With Obstructive Sleep Apnea and Non-Alcoholic Steatohepatitis: A Systematic Review and Meta-Analysis. | 2018 | Details |
A14982 | 29144438 | Antioxidants (Basel) | Bioactive Components in Moringa Oleifera Leaves Protect against Chronic Disease. | 2017 | Details |
A14984 | 29141573 | Endocr Metab Immune Disord Drug Targets | Liver Protective Effects of Extra Virgin Olive Oil: Interaction between Its Chemical Composition and the Cell-signaling Pathways Involved in Protection. | 2018 | Details |
A14985 | 29139555 | Br J Pharmacol | Tauroursodeoxycholic acid inhibits intestinal inflammation and barrier disruption in mice with non-alcoholic fatty liver disease. | 2018 | Details |
A14986 | 29138984 | Curr Hypertens Rep | 11β-Hydroxysteroid Dehydrogenases and Hypertension in the Metabolic Syndrome. | 2017 | Details |
A14987 | 29138227 | Am J Physiol Endocrinol Metab | The hepatokines fetuin-A and fetuin-B are upregulated in the state of hepatic steatosis and may differently impact on glucose homeostasis in humans. | 2017 | Details |
A14989 | 29137289 | Oncotarget | Lingguizhugan decoction improves non-alcoholic fatty liver disease by altering insulin resistance and lipid metabolism related genes: a whole trancriptome study by RNA-Seq. | 2017 | Details |
A14992 | 29133512 | Diabetes | Exosomes From Adipose-Derived Stem Cells Attenuate Adipose Inflammation and Obesity Through Polarizing M2 Macrophages and Beiging in White Adipose Tissue. | 2017 | Details |
A14993 | 29133343 | Diabetes Care | Clinical and Histologic Characterization of Nonalcoholic Steatohepatitis in African American Patients. | 2017 | Details |
A14994 | 29132522 | Prim Care | Nonalcoholic Fatty Liver Disease. | 2017 | Details |
A14999 | 29129819 | Metabolism | Nicotinic acetylcholine receptor α7 subunit improves energy homeostasis and inhibits inflammation in nonalcoholic fatty liver disease. | 2017 | Details |
A15003 | 29128353 | Biochem Biophys Res Commun | Pyruvate dehydrogenase kinase 4 mediates lipogenesis and contributes to the pathogenesis of nonalcoholic steatohepatitis. | 2017 | Details |
A15004 | 29128158 | Trends Endocrinol Metab | Mitogen-Activated Protein Kinase Regulation in Hepatic Metabolism. | 2017 | Details |
A15009 | 29128060 | Clin Liver Dis | Risk Factors for the Development of Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis, Including Genetics. | 2017 | Details |
A15015 | 29128054 | Clin Liver Dis | The Role of Nonalcoholic Fatty Liver Disease on Cardiovascular Manifestations and Outcomes. | 2017 | Details |
A15016 | 29128053 | Clin Liver Dis | Nonalcoholic Fatty Liver Disease and Metabolic Syndrome. | 2017 | Details |
A15017 | 29128052 | Clin Liver Dis | The Intestinal Microbiome in Nonalcoholic Fatty Liver Disease. | 2018 | Details |
A15018 | 29128051 | Clin Liver Dis | The Natural History of Nonalcoholic Fatty Liver Disease-An Evolving View. | 2018 | Details |
A15023 | 29126873 | Mol Metab | Dual role of protein tyrosine phosphatase 1B in the progression and reversion of non-alcoholic steatohepatitis. | 2017 | Details |
A15037 | 29122442 | Nutr Metab Cardiovasc Dis | Serum Fetuin-A levels in obese children with biopsy proven nonalcoholic fatty liver disease. | 2017 | Details |
A15041 | 29121861 | BMC Genomics | Transcriptomics, metabolomics and histology indicate that high-carbohydrate diet negatively affects the liver health of blunt snout bream (Megalobrama amblycephala). | 2017 | Details |
A15050 | 29118811 | Int J Endocrinol | Obese Children with Metabolic Syndrome Have 3 Times Higher Risk to Have Nonalcoholic Fatty Liver Disease Compared with Those without Metabolic Syndrome. | 2017 | Details |
A15051 | 29118561 | Ann Gastroenterol | Pilot study of the prevalence of binge eating disorder in non-alcoholic fatty liver disease patients. | 2017 | Details |
A15052 | 29118014 | Am J Physiol Endocrinol Metab | Exercise training reduces intrahepatic lipid content in people with and people without nonalcoholic fatty liver. | 2017 | Details |
A15059 | 29114377 | Int J Prev Med | Nonalcoholic Fatty Liver Disease in a Sample of Iranian Women with Polycystic Ovary Syndrome. | 2017 | Details |
A15062 | 29113741 | Cytokine | Low serum CTRP3 levels are associated with nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus. | 2017 | Details |
A15065 | 29113028 | Hepatology | Restoration of a healthy intestinal microbiota normalizes portal hypertension in a rat model of nonalcoholic steatohepatitis. | 2018 | Details |
A15069 | 29109528 | Sci Rep | Predictors of Liver Fat and Stiffness in Non-Alcoholic Fatty Liver Disease (NAFLD) - an 11-Year Prospective Study. | 2017 | Details |
A15070 | 29109457 | Sci Rep | Non-alcoholic fatty liver disease is an influencing factor for the association of SHBG with metabolic syndrome in diabetes patients. | 2017 | Details |
A15071 | 29109303 | Clin Sci (Lond) | Insulin resistance and reduced metabolic flexibility: cause or consequence of NAFLD? | 2017 | Details |
A15073 | 29108205 | Zhonghua Gan Zang Bing Za Zhi | [Investigation and analysis of the knowledge of nonalcoholic fatty liver disease among residents in Hebei Province, China]. | 2017 | Details |
A15076 | 29107687 | Biochem Biophys Res Commun | MiR-150 deficiency ameliorated hepatosteatosis and insulin resistance in nonalcoholic fatty liver disease via targeting CASP8 and FADD-like apoptosis regulator. | 2017 | Details |
A15082 | 29106066 | J Dig Dis | Pharmacotherapy of nonalcoholic steatohepatitis: Reflections on the existing evidence. | 2017 | Details |
A15083 | 29104811 | Liver Res | Bile acid metabolism and signaling in liver disease and therapy. | 2017 | Details |
A15085 | 29104232 | Antioxidants (Basel) | Treatment with a Catalytic Superoxide Dismutase (SOD) Mimetic Improves Liver Steatosis, Insulin Sensitivity, and Inflammation in Obesity-Induced Type 2 Diabetes. | 2017 | Details |
A15094 | 29099463 | J Clin Gastroenterol | Associations of Insulin Resistance and Glycemia With Liver Enzymes in Hispanic/Latino Youths: Results From the Hispanic Community Children's Health Study/Study of Latino Youth (SOL Youth). | 2019 | Details |
A15095 | 29098545 | Obes Surg | Non-alcoholic Fatty Liver Disease in Morbidly Obese Individuals Undergoing Bariatric Surgery: Prevalence and Effect of the Pre-Bariatric Very Low Calorie Diet. | 2018 | Details |
A15098 | 29097288 | Diabetes Res Clin Pract | Trend over time in hepatic fibrosis score in a cohort of type 2 diabetes patients. | 2017 | Details |