Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin resistance7794 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A18049 | 27383530 | J Diabetes Investig | Analysis of risk factors and their interactions in type 2 diabetes mellitus: A cross-sectional survey in Guilin, China. | 2016 | Details |
| A18051 | 27382573 | J Diabetes Res | Sex-Specific Association between Serum Uric Acid and Nonalcoholic Fatty Liver Disease in Type 2 Diabetic Patients. | 2016 | Details |
| A18062 | 27377869 | Clin Exp Immunol | MicroRNA-26a-interleukin (IL)-6-IL-17 axis regulates the development of non-alcoholic fatty liver disease in a murine model. | 2016 | Details |
| A18065 | 27374784 | Stem Cells | Concise Review: Current Status and Future Directions on Research Related to Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18069 | 27372863 | Med Hypotheses | Fructose surges damage hepatic adenosyl-monophosphate-dependent kinase and lead to increased lipogenesis and hepatic insulin resistance. | 2016 | Details |
| A18071 | 27371101 | J Diabetes | Correlations of non-alcoholic fatty liver disease and serum uric acid with subclinical atherosclerosis in obese Chinese adults. | 2016 | Details |
| A18081 | 27358638 | Afr Health Sci | Biochemical parameters response to weight loss in patients with non-alcoholic steatohepatitis. | 2016 | Details |
| A18085 | 30695468 | Rinsho Byori | [Progress in the Management of NAFLD/NASH]. | 2016 | Details |
| A18088 | 29201749 | Euroasian J Hepatogastroenterol | Nonalcoholic Fatty Liver Disease in South Asia. | 2016 | Details |
| A18090 | 27355753 | Hepatol Res | Case report of diet-related improvements of non-alcoholic steatohepatitis evaluated by four consecutive liver biopsies. | 2016 | Details |
| A18099 | 27351871 | J Gastroenterol | The risk of transient postprandial oxyhypoglycemia in nonalcoholic fatty liver disease. | 2016 | Details |
| A18104 | 27349927 | Sci Rep | CXCL10-Mediates Macrophage, but not Other Innate Immune Cells-Associated Inflammation in Murine Nonalcoholic Steatohepatitis. | 2016 | Details |
| A18109 | 27347998 | Nutrients | Novel Action of Carotenoids on Non-Alcoholic Fatty Liver Disease: Macrophage Polarization and Liver Homeostasis. | 2016 | Details |
| A18115 | 27345267 | Biochim Biophys Acta Mol Basis Dis | Linking mitochondrial dysfunction, metabolic syndrome and stress signaling in Neurodegeneration. | 2016 | Details |
| A18118 | 27343380 | Eur J Pharmacol | (S)YS-51, a novel isoquinoline alkaloid, attenuates obesity-associated non-alcoholic fatty liver disease in mice by suppressing lipogenesis, inflammation and coagulation. | 2016 | Details |
| A18123 | 27340383 | Immune Netw | The Immune Landscape in Nonalcoholic Steatohepatitis. | 2016 | Details |
| A18127 | 27338619 | Glycoconj J | Dicarbonyl stress in clinical obesity. | 2016 | Details |
| A18137 | 27325692 | J Biol Chem | XBP1s Is an Anti-lipogenic Protein. | 2016 | Details |
| A18138 | 27324703 | J Diabetes Complications | Factors associated with significant liver steatosis and fibrosis as assessed by transient elastography in patients with one or more components of the metabolic syndrome. | 2016 | Details |
| A18139 | 27324067 | Metabolism | Nonalcoholic fatty liver disease and obstructive sleep apnea. | 2016 | Details |
| A18144 | 27322798 | Ann Intern Med | Long-Term Pioglitazone Treatment for Patients With Nonalcoholic Steatohepatitis and Prediabetes or Type 2 Diabetes Mellitus: A Randomized Trial. | 2016 | Details |
| A18145 | 27322467 | EBioMedicine | Low-Density Lipoprotein Receptor-Related Protein-1 Protects Against Hepatic Insulin Resistance and Hepatic Steatosis. | 2016 | Details |
| A18149 | 27321334 | Diabetes Res Clin Pract | The impact of body weight gain on nonalcoholic fatty liver disease and metabolic syndrome during earlier and later adulthood. | 2016 | Details |
| A18156 | 27315552 | Mol Med Rep | Deletion of Nrf2 leads to hepatic insulin resistance via the activation of NF-κB in mice fed a high-fat diet. | 2016 | Details |
| A18157 | 27314342 | Int J Mol Sci | A Guide to Non-Alcoholic Fatty Liver Disease in Childhood and Adolescence. | 2016 | Details |
| A18160 | 27312339 | Sci Rep | Long-term exposure to abnormal glucose levels alters drug metabolism pathways and insulin sensitivity in primary human hepatocytes. | 2016 | Details |
| A18167 | 27310544 | Rev Assoc Med Bras (1992) | Non-alcoholic fatty liver disease (NAFLD) in different populations: A clinical and epidemiological study - sample of São José do Rio Preto. | 2017 | Details |
| A18181 | 27307131 | Phytother Res | Non-alcoholic Fatty Liver Disease: Beneficial Effects of Flavonoids. | 2016 | Details |
| A18185 | 27304953 | Int J Mol Sci | Effects of Probiotics and Synbiotics on Obesity, Insulin Resistance Syndrome, Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease: A Review of Human Clinical Trials. | 2016 | Details |
| A18193 | 27296438 | BMC Gastroenterol | Development of a novel mouse model of hepatocellular carcinoma with nonalcoholic steatohepatitis using a high-fat, choline-deficient diet and intraperitoneal injection of diethylnitrosamine. | 2016 | Details |
| A18205 | 27287838 | Orv Hetil | [Non-alcoholic fatty liver disease and hepatocellular carcinoma - 2016]. | 2016 | Details |
| A18222 | 27276701 | Liver Int | Nonalcoholic fatty liver disease: cause or consequence of type 2 diabetes? | 2016 | Details |
| A18230 | 27270872 | Phytother Res | Treatment of Non-alcoholic Fatty Liver Disease with Curcumin: A Randomized Placebo-controlled Trial. | 2016 | Details |
| A18253 | 27262842 | Acta Biochim Pol | Hepatokines and non-alcoholic fatty liver disease. | 2016 | Details |
| A18257 | 27261776 | Mol Med | Activation of proteinase 3 contributes to Non-alcoholic Fatty Liver Disease (NAFLD) and insulin resistance. | 2016 | Details |
| A18258 | 27261415 | J Hepatol | A diet-induced animal model of non-alcoholic fatty liver disease and hepatocellular cancer. | 2016 | Details |
| A18262 | 27257426 | Hepat Mon | Leptin Receptor Gene Polymorphisms and the Risk of Non-Alcoholic Fatty Liver Disease and Coronary Atherosclerosis in the Chinese Han Population. | 2016 | Details |
| A18266 | 27255583 | J Hepatol | Effect of exercise on the development of new fatty liver and the resolution of existing fatty liver. | 2016 | Details |
| A18267 | 27254774 | Liver Int | ADAMTS5 deficiency protects against non-alcoholic steatohepatitis in obesity. | 2016 | Details |
| A18276 | 27248435 | Curr Protoc Mouse Biol | Development of a Representative Mouse Model with Nonalcoholic Steatohepatitis. | 2016 | Details |
| A18279 | 27246737 | Biochem Biophys Res Commun | Supplementing dietary sugar promotes endoplasmic reticulum stress-independent insulin resistance and fatty liver in goose. | 2016 | Details |
| A18280 | 27246655 | Sci Rep | Association of Non-alcoholic Fatty Liver Disease with Metabolic Syndrome Independently of Central Obesity and Insulin Resistance. | 2016 | Details |
| A18281 | 27245430 | J Hepatol | Hepatocyte vitamin D receptor regulates lipid metabolism and mediates experimental diet-induced steatosis. | 2016 | Details |
| A18285 | 29879345 | Yao Xue Xue Bao | [Investigating the effects of compound WS090152 on non-alcoholic fatty liver in mice]. | 2016 | Details |
| A18288 | 27239734 | Lab Invest | C/EBP homologous protein modulates liraglutide-mediated attenuation of non-alcoholic steatohepatitis. | 2016 | Details |
| A18292 | 27237577 | Metabolism | Non-alcoholic fatty liver disease and dyslipidemia: An update. | 2016 | Details |
| A18298 | 27231906 | Int J Mol Sci | NAFLD and NASH in HCV Infection: Prevalence and Significance in Hepatic and Extrahepatic Manifestations. | 2016 | Details |
| A18303 | 27226903 | Sultan Qaboos Univ Med J | Mechanisms of Diabetes-Induced Liver Damage: The role of oxidative stress and inflammation. | 2016 | Details |
| A18309 | 27221093 | Diabetologia | A novel hepatokine, HFREP1, plays a crucial role in the development of insulin resistance and type 2 diabetes. | 2016 | Details |
| A18317 | 27216550 | J Cell Physiol | Association Between Aerobic Exercise and Rosiglitazone Avoided the NAFLD and Liver Inflammation Exacerbated in PPAR-α Knockout Mice. | 2016 | Details |
| A18322 | 27213061 | Case Rep Endocrinol | Panhypopituitarism due to Absence of the Pituitary Stalk: A Rare Aetiology of Liver Cirrhosis. | 2016 | Details |
| A18324 | 27211699 | Clin Biochem | Serum metabonomics of NAFLD plus T2DM based on liquid chromatography-mass spectrometry. | 2016 | Details |
| A18327 | 27207512 | Diabetes | Variants in Genes Controlling Oxidative Metabolism Contribute to Lower Hepatic ATP Independent of Liver Fat Content in Type 1 Diabetes. | 2016 | Details |
| A18336 | 27197843 | Br J Nutr | Preventive effects of citrulline on Western diet-induced non-alcoholic fatty liver disease in rats. | 2016 | Details |
| A18341 | 27196572 | Gut | Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism. | 2016 | Details |
| A18345 | 27190693 | World J Gastrointest Pathophysiol | Insulin resistance in development and progression of nonalcoholic fatty liver disease. | 2016 | Details |
| A18347 | 27189281 | Yonsei Med J | The Relationship between Type 2 Diabetes Mellitus and Non-Alcoholic Fatty Liver Disease Measured by Controlled Attenuation Parameter. | 2016 | Details |
| A18348 | 27188904 | Nutr Res | Alternate-day fasting protects the livers of mice against high-fat diet-induced inflammation associated with the suppression of Toll-like receptor 4/nuclear factor κB signaling. | 2016 | Details |
| A18350 | 27187452 | Nutrients | Gut Microbiota and Metabolic Health: The Potential Beneficial Effects of a Medium Chain Triglyceride Diet in Obese Individuals. | 2016 | Details |
| A18351 | 27187365 | Int J Mol Sci | Non-Alcoholic Fatty Liver Disease and Extra-Hepatic Cancers. | 2016 | Details |
| A18352 | 27185609 | Lancet Diabetes Endocrinol | Phenotypes of prediabetes and stratification of cardiometabolic risk. | 2016 | Details |
| A18355 | 27185080 | Am J Gastroenterol | Metabolically Healthy Obesity and the Development of Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18356 | 27184920 | Sci Rep | Preventing High Fat Diet-induced Obesity and Improving Insulin Sensitivity through Neuregulin 4 Gene Transfer. | 2016 | Details |
| A18362 | 27181889 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | [Roles of MicroRNA-21 in the Pathogenesis of Insulin Resistance and Diabetic Mellitus-induced Non-alcoholic Fatty Liver Disease]. | 2016 | Details |
| A18370 | 27178444 | Liver Int | Advanced non-alcoholic fatty liver disease and adipose tissue fibrosis in patients with Alström syndrome. | 2016 | Details |
| A18378 | 27173514 | Environ Int | Association between exposures to brominated trihalomethanes, hepatic injury and type II diabetes mellitus. | 2016 | Details |
| A18379 | 27173510 | Am J Physiol Gastrointest Liver Physiol | Compounds of the sphingomyelin-ceramide-glycosphingolipid pathways as secondary messenger molecules: new targets for novel therapies for fatty liver disease and insulin resistance. | 2016 | Details |
| A18382 | 27172901 | Oncotarget | IL-33 treatment attenuated diet-induced hepatic steatosis but aggravated hepatic fibrosis. | 2016 | Details |
| A18386 | 27170389 | Dig Dis | Non-Alcoholic Steatohepatitis: From Pathophysiology to Novel Therapies. | 2016 | Details |
| A18387 | 27169860 | BMC Res Notes | Subclinical inflammation in relation to insulin resistance in prediabetic subjects with nonalcoholic fatty liver disease. | 2016 | Details |
| A18390 | 27166773 | Clinics (Sao Paulo) | FT3/FT4 ratio predicts non-alcoholic fatty liver disease independent of metabolic parameters in patients with euthyroidism and hypothyroidism. | 2016 | Details |
| A18391 | 27166182 | Oncotarget | Reduced miR-200b and miR-200c expression contributes to abnormal hepatic lipid accumulation by stimulating JUN expression and activating the transcription of srebp1. | 2016 | Details |
| A18393 | 27164963 | Chin J Integr Med | Protective Effects of Chaihu Shugan San () on Nonalcoholic Fatty Liver Disease in Rats with Insulin Resistance. | 2016 | Details |
| A18398 | 27160697 | Dig Liver Dis | Non-alcoholic fatty liver disease fibrosis score and preclinical vascular damage in morbidly obese patients. | 2016 | Details |
| A18408 | 27153234 | Chemosphere | Metabolic and immune impairments induced by the endocrine disruptors benzo[a]pyrene and triclosan in Xenopus tropicalis. | 2016 | Details |
| A18412 | 27151177 | J Hepatol | Sitagliptin vs. placebo for non-alcoholic fatty liver disease: A randomized controlled trial. | 2016 | Details |
| A18420 | 27146015 | Annu Rev Nutr | Citrus Flavonoids as Regulators of Lipoprotein Metabolism and Atherosclerosis. | 2016 | Details |
| A18422 | 27146012 | Annu Rev Nutr | Alterations of Mitochondrial Function and Insulin Sensitivity in Human Obesity and Diabetes Mellitus. | 2016 | Details |
| A18423 | 27145114 | Mol Nutr Food Res | Biochanin A improves hepatic steatosis and insulin resistance by regulating the hepatic lipid and glucose metabolic pathways in diet-induced obese mice. | 2016 | Details |
| A18424 | 27145007 | Endocrinology | Maternal Hyperleptinemia Improves Offspring Insulin Sensitivity in Mice. | 2016 | Details |
| A18429 | 27142870 | Diabetes Metab | Risk of type 2 diabetes in patients with non-alcoholic fatty liver disease: Causal association or epiphenomenon? | 2016 | Details |
| A18440 | 27134062 | Nutr Metab Cardiovasc Dis | Insulin resistance, postprandial GLP-1 and adaptive immunity are the main predictors of NAFLD in a homogeneous population at high cardiovascular risk. | 2016 | Details |
| A18448 | 27128911 | Int J Mol Sci | Definitions of Normal Liver Fat and the Association of Insulin Sensitivity with Acquired and Genetic NAFLD-A Systematic Review. | 2016 | Details |
| A18453 | 27124954 | Genome Med | Antibiotic perturbation of the murine gut microbiome enhances the adiposity, insulin resistance, and liver disease associated with high-fat diet. | 2016 | Details |
| A18454 | 27124606 | J Cardiovasc Pharmacol | Curcumin Lowers Serum Lipids and Uric Acid in Subjects With Nonalcoholic Fatty Liver Disease: A Randomized Controlled Trial. | 2016 | Details |
| A18457 | 27122660 | World J Gastroenterol | Nonalcoholic fatty liver disease as a multi-systemic disease. | 2016 | Details |
| A18458 | 27121255 | Int J Obes (Lond) | Intervention with a caspase-1 inhibitor reduces obesity-associated hyperinsulinemia, non-alcoholic steatohepatitis and hepatic fibrosis in LDLR-/-.Leiden mice. | 2016 | Details |
| A18459 | 27121253 | Int J Obes (Lond) | Reduced circulating levels of sTWEAK are associated with NAFLD and may affect hepatocyte triglyceride accumulation. | 2016 | Details |
| A18464 | 27110380 | BMJ Open Gastroenterol | Statins, antidiabetic medications and liver histology in patients with diabetes with non-alcoholic fatty liver disease. | 2016 | Details |
| A18466 | 27110262 | Hepat Mon | Ginger Supplementation in Nonalcoholic Fatty Liver Disease: A Randomized, Double-Blind, Placebo-Controlled Pilot Study. | 2016 | Details |
| A18470 | 27107966 | Best Pract Res Clin Obstet Gynaecol | Hepatic manifestations of women with polycystic ovary syndrome. | 2016 | Details |
| A18472 | 27106721 | Diabetologia | Higher body fat percentage is associated with enhanced temperature perception in NAFLD: results from the randomised Wessex Evaluation of fatty Liver and Cardiovascular markers in NAFLD with OMacor thErapy trial (WELCOME) trial. | 2016 | Details |
| A18476 | 27104558 | Nutrients | Insulin Protects Hepatic Lipotoxicity by Regulating ER Stress through the PI3K/Akt/p53 Involved Pathway Independently of Autophagy Inhibition. | 2016 | Details |
| A18484 | 27101131 | Diabetologia | Treatment of patients with type 2 diabetes and non-alcoholic fatty liver disease: current approaches and future directions. | 2016 | Details |
| A18495 | 27091156 | Cell Mol Life Sci | Hypoxia-regulated mechanisms in the pathogenesis of obesity and non-alcoholic fatty liver disease. | 2016 | Details |
| A18500 | 27089408 | J Pediatr Endocrinol Metab | Low 25-hydroxyvitamin D level is not an independent risk factor for hepatosteatosis in obese children. | 2016 | Details |
| A18514 | 27077854 | Int J Mol Sci | Role of Serum Uric Acid and Ferritin in the Development and Progression of NAFLD. | 2016 | Details |
| A18518 | 27076501 | Hum Reprod | Non-alcoholic fatty liver disease is associated with insulin resistance and lipid accumulation product in women with polycystic ovary syndrome. | 2016 | Details |
| A18523 | 27073470 | Exp Ther Med | Low simvastatin concentrations reduce oleic acid-induced steatosis in HepG2 cells: An in vitro model of non-alcoholic fatty liver disease. | 2016 | Details |
| A18524 | 27072576 | Oncotarget | Utilization of animal models to investigate nonalcoholic steatohepatitis-associated hepatocellular carcinoma. | 2016 | Details |