Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A20511 | 25915484 | Curr Drug Targets | Antioxidant Mechanisms in Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A20528 | 25910292 | Turk J Gastroenterol | Fatty liver disease might increase the risk of abdominal operation in patients with fatty liver and the prevalence of cancer in first-degree relatives. | 2014 | Details |
| A20531 | 25906757 | J Endocrinol Invest | 1,25(OH)2D3 downregulates the Toll-like receptor 4-mediated inflammatory pathway and ameliorates liver injury in diabetic rats. | 2015 | Details |
| A20535 | 25905791 | Food Funct | Differences and similarities in hepatic lipogenesis, gluconeogenesis and oxidative imbalance in mice fed diets rich in fructose or sucrose. | 2015 | Details |
| A20542 | 25904325 | Mol Biol Cell | CHOP links endoplasmic reticulum stress to NF-κB activation in the pathogenesis of nonalcoholic steatohepatitis. | 2015 | Details |
| A20544 | 25897647 | Crit Rev Food Sci Nutr | The potential of flavonoids in the treatment of non-alcoholic fatty liver disease. | 2017 | Details |
| A20545 | 25896720 | Pharmacology | Fenofibrate treatment attenuated chronic endoplasmic reticulum stress in the liver of nonalcoholic fatty liver disease mice. | 2015 | Details |
| A20548 | 25894568 | Clin Exp Med | Severity of non-alcoholic fatty liver disease is associated with high systemic levels of tumor necrosis factor alpha and low serum interleukin 10 in morbidly obese patients. | 2015 | Details |
| A20550 | 25892963 | Int J Biol Sci | ER stress and autophagy dysfunction contribute to fatty liver in diabetic mice. | 2015 | Details |
| A20557 | 25889212 | J Transl Med | Docosahexaenoic acid and non-alcoholic fatty liver disease in obese children: a novel approach? | 2015 | Details |
| A20560 | 25886887 | BMC Gastroenterol | Fluvastatin attenuates hepatic steatosis-induced fibrogenesis in rats through inhibiting paracrine effect of hepatocyte on hepatic stellate cells. | 2015 | Details |
| A20579 | 25875119 | Nutrients | A green algae mixture of Scenedesmus and Schroederiella attenuates obesity-linked metabolic syndrome in rats. | 2015 | Details |
| A20581 | 25873773 | Mediators Inflamm | OSAS-related inflammatory mechanisms of liver injury in nonalcoholic fatty liver disease. | 2015 | Details |
| A20584 | 25873078 | Exp Biol Med (Maywood) | Nonalcoholic fatty liver disease: update on pathogenesis, diagnosis, treatment and the role of S-adenosylmethionine. | 2015 | Details |
| A20585 | 25871295 | Mar Drugs | Anti-obesity activity of the marine carotenoid fucoxanthin. | 2015 | Details |
| A20589 | 25869759 | Wien Klin Wochenschr | Nonalcoholic fatty liver may increase the risk of operation in patients with fatty liver and the frequency of cancer in their first-degree relatives. | 2015 | Details |
| A20591 | 25868633 | Dig Dis Sci | Raloxifene Ameliorates Liver Fibrosis of Nonalcoholic Steatohepatitis Induced by Choline-Deficient High-Fat Diet in Ovariectomized Mice. | 2015 | Details |
| A20595 | 25865747 | Obesity (Silver Spring) | Serum autotaxin is independently associated with hepatic steatosis in women with severe obesity. | 2015 | Details |
| A20596 | 25865685 | Hepatobiliary Pancreat Dis Int | Beneficial mechanisms of aerobic exercise on hepatic lipid metabolism in non-alcoholic fatty liver disease. | 2015 | Details |
| A20608 | 25853894 | Horm Metab Res | A Nonclassical Monocyte Phenotype in Peripheral Blood is Associated with Nonalcoholic Fatty Liver Disease: A Report from an EMIL Subcohort. | 2015 | Details |
| A20609 | 25852271 | World J Gastroenterol | Insulin-like growth factor-1 mRNA isoforms and insulin-like growth factor-1 receptor mRNA expression in chronic hepatitis C. | 2015 | Details |
| A20610 | 25852263 | World J Gastroenterol | Current pharmacological therapies for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. | 2015 | Details |
| A20621 | 25848479 | World J Hepatol | Probiotics as a complementary therapeutic approach in nonalcoholic fatty liver disease. | 2015 | Details |
| A20623 | 25848461 | World J Hepatol | Non-alcoholic fatty liver disease and psoriasis: So far, so near. | 2015 | Details |
| A20632 | 25845417 | Liver Int | The association between the serum levels of uric acid and alanine aminotransferase in a population-based cohort. | 2015 | Details |
| A20643 | 25837920 | J Pharmacol Sci | Effect of oleoylethanolamide on diet-induced nonalcoholic fatty liver in rats. | 2014 | Details |
| A20660 | 28511747 | Acta Dermatovenerol Croat | Red Blood Cell Distribution Width is a Reliable Marker of Inflammation in Plaque Psoriasis. | 2017 | Details |
| A20661 | 27308418 | Mol Cell Oncol | KEAP the balance between life and death. | 2014 | Details |
| A20669 | 25817233 | Life Sci | AMP-kinase pathway is involved in tumor necrosis factor alpha-induced lipid accumulation in human hepatoma cells. | 2015 | Details |
| A20670 | 25816330 | PLoS One | Eicosapentaenoic acid ameliorates non-alcoholic steatohepatitis in a novel mouse model using melanocortin 4 receptor-deficient mice. | 2015 | Details |
| A20672 | 25815106 | Oxid Med Cell Longev | P2X7 receptor as a key player in oxidative stress-driven cell fate in nonalcoholic steatohepatitis. | 2015 | Details |
| A20673 | 25814186 | Pharmacol Res | Effect of resveratrol on experimental non-alcoholic steatohepatitis. | 2015 | Details |
| A20688 | 25798066 | Int J Biol Sci | Stem cell transplantation upregulates Sirt1 and antioxidant expression, ameliorating fatty liver in type 2 diabetic mice. | 2015 | Details |
| A20697 | 25794039 | J Am Coll Nutr | Consumption of Oxidized and Partially Hydrogenated Oils Differentially Induces Trans-Fatty Acids Incorporation in Rats' Heart and Dyslipidemia. | 2015 | Details |
| A20700 | 25790822 | Exp Biol Med (Maywood) | Sex hormone affects the severity of non-alcoholic steatohepatitis through the MyD88-dependent IL-6 signaling pathway. | 2015 | Details |
| A20704 | 25788761 | Mediators Inflamm | Presence of fatty liver and the relationship between alcohol consumption and markers of inflammation. | 2015 | Details |
| A20731 | 25772181 | Endocr Metab Immune Disord Drug Targets | Adiponectin as a Target in Obesity-related Inflammatory State. | 2015 | Details |
| A20759 | 25751957 | Zhongguo Zhong Yao Za Zhi | [Effects of soothing liver and invigorating spleen recipes on LPS-induced hepatocytes injury of rats and TLR4/p38MAPK signal pathway]. | 2014 | Details |
| A20760 | 25751727 | Int J Mol Sci | Potential epigenetic mechanism in non-alcoholic Fatty liver disease. | 2015 | Details |
| A20761 | 25751390 | Zhonghua Gan Zang Bing Za Zhi | [Effects and mechanisms of the inflammatory reaction related to NASH and induced by activation of the cholinergic anti-inflammatory pathway]. | 2015 | Details |
| A20786 | 25736100 | Cancer Sci | Suppression of silent information regulator 1 activity in noncancerous tissues of hepatocellular carcinoma: Possible association with non-B non-C hepatitis pathogenesis. | 2015 | Details |
| A20795 | 25729762 | Cell Mol Gastroenterol Hepatol | Death Receptor-Mediated Cell Death and Proinflammatory Signaling in Nonalcoholic Steatohepatitis. | 2015 | Details |
| A20796 | 25729707 | Diabetes Metab J | Hepatokines as a Link between Obesity and Cardiovascular Diseases. | 2015 | Details |
| A20799 | 25729475 | World J Hepatol | Recent advances in dietary supplementation, in treating non-alcoholic fatty liver disease. | 2015 | Details |
| A20809 | 25717419 | J Mol Biomark Diagn | YKL-40 is a Protective Biomarker for Fatty Liver in World Trade Center Particulate Matter-Exposed Firefighters. | 2020 | Details |
| A20811 | 25716965 | J Physiol Pharmacol | Inflammatory response in visceral fat tissue and liver is prenatally programmed: experimental research. | 2015 | Details |
| A20821 | 25713801 | Hepatobiliary Surg Nutr | Immunoregulation by lipids during the development of non-alcoholic steatohepatitis. | 2015 | Details |
| A20841 | 25697114 | Med Hypotheses | Serum levels of toxic AGEs (TAGE) may be a promising novel biomarker in development and progression of NASH. | 2015 | Details |
| A20849 | 25688578 | Hemodial Int | Relationship between non-alcoholic fatty liver disease and MIA syndrome. | 2015 | Details |
| A20859 | 25681756 | Exp Mol Pathol | Resolvin E1 and chemerin C15 peptide do not improve rodent non-alcoholic steatohepatitis. | 2015 | Details |
| A20861 | 25681399 | Gut | Pathobiology of liver fibrosis: a translational success story. | 2015 | Details |
| A20880 | 25668433 | PLoS Negl Trop Dis | Trypanosoma cruzi infection is a potent risk factor for non-alcoholic steatohepatitis enhancing local and systemic inflammation associated with strong oxidative stress and metabolic disorders. | 2015 | Details |
| A20894 | 25658238 | Nutrients | 6-gingerol protects against nutritional steatohepatitis by regulating key genes related to inflammation and lipid metabolism. | 2015 | Details |
| A20896 | 25655997 | J Ethnopharmacol | Total aralosides of aralia elata (Miq) seem (TASAES) ameliorate nonalcoholic steatohepatitis by modulating IRE1α-mediated JNK and NF-κB pathways in ApoE-/- mice. | 2015 | Details |
| A20905 | 25654080 | Front Med (Lausanne) | Management of moderate to severe psoriasis in patients with metabolic comorbidities. | 2015 | Details |
| A20917 | 25646700 | Liver Int | Beneficial effects of mineralocorticoid receptor blockade in experimental non-alcoholic steatohepatitis. | 2015 | Details |
| A20931 | 25633064 | Arch Dis Child | Paediatric non-alcoholic fatty liver disease: a practical overview for non-specialists. | 2015 | Details |
| A20978 | 25606030 | Case Rep Gastroenterol | A 25-year-old woman with type 2 diabetes and liver disease. | 2014 | Details |
| A20981 | 25604802 | Expert Opin Investig Drugs | Early investigational drugs targeting PPAR-α for the treatment of metabolic disease. | 2015 | Details |
| A20985 | 25602171 | Antioxid Redox Signal | Reactive oxygen species-induced TXNIP drives fructose-mediated hepatic inflammation and lipid accumulation through NLRP3 inflammasome activation. | 2015 | Details |
| A20991 | 25598995 | J Clin Exp Cardiolog | Association between inflammatory markers and liver fat: The Multi-Ethnic Study of Atherosclerosis. | 2022 | Details |
| A20995 | 25597144 | J Egypt Soc Parasitol | Pharmacological and antioxidant actions of garlic and.or onion in non-alcoholic fatty liver disease (NAFLD) in rats. | 2014 | Details |
| A21004 | 25583095 | Clin Biochem | Laboratory assessment of cardiometabolic risk in overweight and obese children. | 2015 | Details |
| A21006 | 25581573 | Liver Int | TM6SF2 E167K variant is associated with severe steatosis in chronic hepatitis C, regardless of PNPLA3 polymorphism. | 2015 | Details |
| A21014 | 25576095 | J Nutr Biochem | Maternal taurine supplementation attenuates maternal fructose-induced metabolic and inflammatory dysregulation and partially reverses adverse metabolic programming in offspring. | 2014 | Details |
| A21021 | 25573175 | Am J Physiol Gastrointest Liver Physiol | Chronic NOS inhibition accelerates NAFLD progression in an obese rat model. | 2015 | Details |
| A21024 | 25568861 | Hepatobiliary Surg Nutr | Innate immune signaling and gut-liver interactions in non-alcoholic fatty liver disease. | 2014 | Details |
| A21035 | 25563215 | Eur J Pediatr | The intestinal microbiota: its role in health and disease. | 2015 | Details |
| A21036 | 25563143 | Eur J Gastroenterol Hepatol | Nonalcoholic fatty liver disease as a potential risk factor of cardiovascular disease. | 2015 | Details |
| A21038 | 25562318 | J Clin Invest | Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis. | 2014 | Details |
| A21039 | 25562147 | Cell Physiol Biochem | Aberrant hepatic microRNA expression in nonalcoholic fatty liver disease. | 2014 | Details |
| A21041 | 25561778 | World J Gastroenterol | Adipokines and proinflammatory cytokines, the key mediators in the pathogenesis of nonalcoholic fatty liver disease. | 2014 | Details |
| A21044 | 25559563 | J Gastroenterol Hepatol | MiR-146b attenuates high-fat diet-induced non-alcoholic steatohepatitis in mice. | 2015 | Details |
| A21051 | 25553772 | Expert Opin Drug Metab Toxicol | Farnesoid x receptor in human metabolism and disease: the interplay between gene polymorphisms, clinical phenotypes and disease susceptibility. | 2015 | Details |
| A21064 | 27453880 | J Diabetes Metab Disord | The effects of onion consumption on treatment of metabolic, histologic, and inflammatory features of nonalcoholic fatty liver disease. | 2016 | Details |
| A21078 | 25548482 | World J Gastroenterol | Elevated free cholesterol in a p62 overexpression model of non-alcoholic steatohepatitis. | 2014 | Details |
| A21079 | 25548472 | World J Gastroenterol | Intestinal microbiota and type 2 diabetes: from mechanism insights to therapeutic perspective. | 2014 | Details |
| A21081 | 25544877 | World J Hepatol | Vitamin D deficiency in chronic liver disease. | 2014 | Details |
| A21089 | 25542756 | Eur J Pharmacol | Ameliorative effect of nicorandil on high fat diet induced non-alcoholic fatty liver disease in rats. | 2014 | Details |
| A21091 | 25541279 | Prostaglandins Leukot Essent Fatty Acids | Ameliorative potential of omega 3 fatty acids and HMG-CoA reductase inhibitors on experimentally-induced non-alcoholic steatohepatitis. | 2014 | Details |
| A21099 | 25536648 | Ann Hepatol | Effects of a low-fat diet on the hepatic expression of adiponectin and its receptors in rats with NAFLD. | 2015 | Details |
| A21104 | 25534442 | Life Sci | Role of physical exercise on hepatic insulin, glucocorticoid and inflammatory signaling pathways in an animal model of non-alcoholic steatohepatitis. | 2014 | Details |
| A21106 | 25534427 | Mol Cell Endocrinol | Down-regulation of miR-144 elicits proinflammatory cytokine production by targeting toll-like receptor 2 in nonalcoholic steatohepatitis of high-fat-diet-induced metabolic syndrome E3 rats. | 2014 | Details |
| A21108 | 25533429 | Eur J Gastroenterol Hepatol | Effects of ursodeoxycholic acid therapy on carotid intima media thickness, apolipoprotein A1, apolipoprotein B, and apolipoprotein B/A1 ratio in nonalcoholic steatohepatitis. | 2015 | Details |
| A21113 | 25532375 | Zhongguo Zhong Yao Za Zhi | [Clinical characteristics and combined use of medicine analysis of 2 991 hospitalized patients with psoriasis based on real world database]. | 2014 | Details |
| A21115 | 25532002 | J Gastrointestin Liver Dis | Non-invasive biomarkers in non-alcoholic steatohepatitis-induced hepatocellular carcinoma. | 2014 | Details |
| A21122 | 25528857 | Lik Sprava | [Hyperhomocysteinemia--a predictor of inflammatory changes in the liver]. | 2014 | Details |
| A21140 | 25520925 | Biomedicine (Taipei) | Auricularia polytricha aqueous extract supplementation decreases hepatic lipid accumulation and improves antioxidative status in animal model of nonalcoholic fatty liver. | 2014 | Details |
| A21142 | 25518481 | Eksp Klin Gastroenterol | [Possibilities of using the noninvasive methods of investigating the morphofunctional changes in the liver in patients with non alcoholic steatohepatitis and type 2 diabetes mellitus]. | 2014 | Details |
| A21143 | 25516477 | Metabolism | The role of fibroblast growth factor 21 in the pathogenesis of non-alcoholic fatty liver disease and implications for therapy. | 2014 | Details |
| A21148 | 25514914 | Rev Recent Clin Trials | Phytotherapy and NAFLD--from goals and challenges to clinical practice. | 2014 | Details |
| A21153 | 25514909 | Rev Recent Clin Trials | Role of adipokines and cytokines in non-alcoholic fatty liver disease. | 2014 | Details |
| A21156 | 25514555 | J Hepatol | Mirtoselect, an anthocyanin-rich bilberry extract, attenuates non-alcoholic steatohepatitis and associated fibrosis in ApoE(∗)3Leiden mice. | 2014 | Details |
| A21158 | 25514388 | Nutrients | The role of dietary sugars and de novo lipogenesis in non-alcoholic fatty liver disease. | 2014 | Details |
| A21163 | 25512222 | BMC Gastroenterol | Expression of NALPs in adipose and the fibrotic progression of non-alcoholic fatty liver disease in obese subjects. | 2014 | Details |
| A21165 | 25509904 | Ter Arkh | [[Current approaches to diagnosing and treating nonalcoholic fatty liver disease]. | 2014 | Details |
| A21171 | 25502558 | PLoS One | A model of metabolic syndrome and related diseases with intestinal endotoxemia in rats fed a high fat and high sucrose diet. | 2014 | Details |
| A21183 | 25495373 | Liver Int | ELF score ≥9.8 indicates advanced hepatic fibrosis and is influenced by age, steatosis and histological activity. | 2015 | Details |
| A21185 | 25493023 | World J Gastroenterol | Increased circulating zonulin in children with biopsy-proven nonalcoholic fatty liver disease. | 2014 | Details |
| A21221 | 25470242 | PLoS One | Neurotropin suppresses inflammatory cytokine expression and cell death through suppression of NF-κB and JNK in hepatocytes. | 2014 | Details |