Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A17409 | 27797398 | Eur J Clin Invest | Hepatic chemerin mRNA expression is reduced in human nonalcoholic steatohepatitis. | 2016 | Details |
| A17418 | 27794176 | Hepatol Res | High fasting insulin concentrations may be a pivotal predictor for the severity of hepatic fibrosis beyond the glycemic status in non-alcoholic fatty liver disease patients before development of diabetes mellitus. | 2016 | Details |
| A17419 | 27794174 | Mol Nutr Food Res | Polyphenol-rich virgin olive oil reduces insulin resistance and liver inflammation and improves mitochondrial dysfunction in high-fat diet fed rats. | 2016 | Details |
| A17421 | 27792214 | Minerva Endocrinol | Prevalence, etiology and management of non-alcoholic fatty liver disease in patients with polycystic ovary syndrome. | 2016 | Details |
| A17423 | 27788733 | Zhonghua Gan Zang Bing Za Zhi | [Fine particulate matter and nonalcoholic fatty liver disease]. | 2016 | Details |
| A17425 | 27788715 | Zhonghua Gan Zang Bing Za Zhi | [Autophagy and nonalcoholic fatty liver disease]. | 2016 | Details |
| A17428 | 27788707 | Zhonghua Gan Zang Bing Za Zhi | [Effect of JAZF1 over-expression on high-fat diet-induced non-alcoholic fatty liver disease]. | 2016 | Details |
| A17431 | 27769711 | Chem Biol Interact | Esculetin prevents non-alcoholic fatty liver in diabetic mice fed high-fat diet. | 2016 | Details |
| A17432 | 27710160 | Metab Syndr Relat Disord | Treatment of Nonalcoholic Fatty Liver Disease with Long-Chain n-3 Polyunsaturated Fatty Acids in Humans. | 2016 | Details |
| A17435 | 27605663 | J Biol Chem | Sevelamer Improves Steatohepatitis, Inhibits Liver and Intestinal Farnesoid X Receptor (FXR), and Reverses Innate Immune Dysregulation in a Mouse Model of Non-alcoholic Fatty Liver Disease. | 2016 | Details |
| A17441 | 27785306 | Gastroenterology Res | Association of the Nonalcoholic Hepatic Steatosis and Its Degrees With the Values of Liver Enzymes and Homeostasis Model Assessment-Insulin Resistance Index. | 2015 | Details |
| A17445 | 27653239 | Hepatol Res | Rosuvastatin limits the activation of hepatic stellate cells in diet-induced obese mice. | 2016 | Details |
| A17448 | 26971094 | J Gastroenterol | Low alcohol consumption increases the risk of impaired glucose tolerance in patients with non-alcoholic fatty liver disease. | 2016 | Details |
| A17449 | 27784003 | Oncotarget | Glycine protects against high sucrose and high fat-induced non-alcoholic steatohepatitis in rats. | 2016 | Details |
| A17456 | 27779710 | Mol Med Rep | Antihypertensive therapy improves insulin resistance and serum levels of interleukin-6 and -10 in spontaneously hypertensive rats with steatohepatitis. | 2016 | Details |
| A17469 | 27774883 | Curr Mol Med | Novel Aspects in the Pathogenesis of Nonalcoholic Steatohepatitis. | 2016 | Details |
| A17478 | 27619543 | J Nutr Biochem | Cranberry extract attenuates hepatic inflammation in high-fat-fed obese mice. | 2016 | Details |
| A17480 | 27522549 | Dig Liver Dis | Transient elastography in healthy subjects and factors influencing liver stiffness in non-alcoholic fatty liver disease: An Italian community-based population study. | 2016 | Details |
| A17481 | 27490779 | Biomed Pharmacother | Swertiamarin ameliorates oleic acid induced lipid accumulation and oxidative stress by attenuating gluconeogenesis and lipogenesis in hepatic steatosis. | 2016 | Details |
| A17489 | 27768254 | Obesity (Silver Spring) | Reduced expression of chemerin in visceral adipose tissue associates with hepatic steatosis in patients with obesity. | 2016 | Details |
| A17491 | 27765690 | Gastroenterology | Isocaloric Diets High in Animal or Plant Protein Reduce Liver Fat and Inflammation in Individuals With Type 2 Diabetes. | 2016 | Details |
| A17501 | 27315352 | Hepatology | Shared genetic effects between hepatic steatosis and fibrosis: A prospective twin study. | 2016 | Details |
| A17502 | 27301788 | Hepatology | Receptor interacting protein 3 protects mice from high-fat diet-induced liver injury. | 2016 | Details |
| A17509 | 27764892 | Pediatr Obes | Association between plasminogen activator inhibitor-1 and severity of liver injury and cardiovascular risk in children with non-alcoholic fatty liver disease. | 2016 | Details |
| A17510 | 27764764 | Physiol Genomics | Transcriptomic differences in intra-abdominal adipose tissue in extremely obese adolescents with different stages of NAFLD. | 2016 | Details |
| A17514 | 27761469 | J Diabetes Res | Effect of Alkaloids from Nelumbinis Plumula against Insulin Resistance of High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease in Mice. | 2016 | Details |
| A17519 | 27759627 | Medicine (Baltimore) | Thiazolidinediones for nonalcoholic steatohepatitis: A meta-analysis of randomized clinical trials. | 2016 | Details |
| A17526 | 27756518 | Nutr Metab Cardiovasc Dis | Intracellular and extracellular miRNome deregulation in cellular models of NAFLD or NASH: Clinical implications. | 2016 | Details |
| A17527 | 27738106 | J Biol Chem | Biliverdin Reductase A Attenuates Hepatic Steatosis by Inhibition of Glycogen Synthase Kinase (GSK) 3β Phosphorylation of Serine 73 of Peroxisome Proliferator-activated Receptor (PPAR) α. | 2016 | Details |
| A17528 | 27717115 | J Sci Food Agric | Pomegranate juice prevents development of non-alcoholic fatty liver disease in rats by attenuating oxidative stress and inflammation. | 2016 | Details |
| A17533 | 27565538 | Antioxid Redox Signal | Dimethylarginine Dimethylaminohydrolase 1 Protects Against High-Fat Diet-Induced Hepatic Steatosis and Insulin Resistance in Mice. | 2016 | Details |
| A17540 | 27754444 | Molecules | The Potential Mechanisms of Berberine in the Treatment of Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A17547 | 27572941 | Dig Dis Sci | Diet-Induced Nonalcoholic Fatty Liver Disease Is Associated with Sarcopenia and Decreased Serum Insulin-Like Growth Factor-1. | 2016 | Details |
| A17558 | 27748192 | Curr Pharm Des | Is There a Role for Curcumin Supplementation in the Treatment of Non-Alcoholic Fatty Liver Disease? The Data Suggest Yes. | 2017 | Details |
| A17561 | 27583706 | Curr Opin Clin Nutr Metab Care | Current evidence on the health-beneficial effects of berry fruits in the prevention and treatment of metabolic syndrome. | 2016 | Details |
| A17573 | 27740518 | Ann Hepatol |  Most overweight and obese Indian children have nonalcoholic fatty liver disease. | 2017 | Details |
| A17585 | 27733832 | Front Pharmacol | Silymarin Ameliorates Metabolic Dysfunction Associated with Diet-Induced Obesity via Activation of Farnesyl X Receptor. | 2016 | Details |
| A17587 | 27732328 | J Clin Endocrinol Metab | Effect of Liraglutide Therapy on Liver Fat Content in Patients With Inadequately Controlled Type 2 Diabetes: The Lira-NAFLD Study. | 2017 | Details |
| A17588 | 27730776 | J Assoc Physicians India | Cardiac Diastolic Dysfunction and Regional Body Fat Distribution in Insulin Resistant Peripubertal Obese Males. | 2016 | Details |
| A17591 | 27729736 | World J Gastroenterol | Hepatocellular carcinoma in patients with non-alcoholic fatty liver disease. | 2016 | Details |
| A17595 | 27727520 | Liver Int | The therapeutic landscape of non-alcoholic steatohepatitis. | 2016 | Details |
| A17596 | 27727322 | PLoS One | Identification of Putative Receptors for the Novel Adipokine CTRP3 Using Ligand-Receptor Capture Technology. | 2016 | Details |
| A17600 | 27723801 | PLoS One | Evaluation of Methionine Content in a High-Fat and Choline-Deficient Diet on Body Weight Gain and the Development of Non-Alcoholic Steatohepatitis in Mice. | 2016 | Details |
| A17604 | 27721919 | World J Hepatol | Independent effects of diet and exercise training on fat oxidation in non-alcoholic fatty liver disease. | 2016 | Details |
| A17606 | 27721459 | Sci Rep | IGF-I induces senescence of hepatic stellate cells and limits fibrosis in a p53-dependent manner. | 2016 | Details |
| A17608 | 27720403 | Clin Nutr | Effect of daily calcitriol supplementation with and without calcium on disease regression in non-alcoholic fatty liver patients following an energy-restricted diet: Randomized, controlled, double-blind trial. | 2016 | Details |
| A17613 | 27715400 | J Clin Endocrinol Metab | Genetic Variation in the 11β-hydroxysteroid-dehydrogenase 1 Gene Determines NAFLD and Visceral Obesity. | 2016 | Details |
| A17614 | 27714510 | Dig Dis Sci | Cardiovascular Risk Reduction in Patients with Nonalcoholic Fatty Liver Disease: The Potential Role of Ezetimibe. | 2016 | Details |
| A17624 | 27709854 | J Korean Med Sci | The Risk for Insulin Resistance according to the Degree of Non-Alcoholic Fatty Liver Disease in Korean Men. | 2016 | Details |
| A17627 | 27708333 | Nat Commun | Differential hepatic distribution of insulin receptor substrates causes selective insulin resistance in diabetes and obesity. | 2016 | Details |
| A17630 | 27703473 | Front Genet | Gender Differences in Adipocyte Metabolism and Liver Cancer Progression. | 2016 | Details |
| A17632 | 27701849 | J Diabetes | Short sleep duration and longer daytime napping are associated with non-alcoholic fatty liver disease in Chinese adults. | 2016 | Details |
| A17633 | 27699229 | JCI Insight | Quantum coherence spectroscopy to measure dietary fat retention in the liver. | 2016 | Details |
| A17637 | 27697366 | C R Biol | High carbohydrate diet induces nonalcoholic steato-hepatitis (NASH) in a desert gerbil. | 2016 | Details |
| A17639 | 27695900 | Diabetologia | An oxidative stress paradox: time for a conceptual change? | 2016 | Details |
| A17646 | 27690306 | Medwave | Liver steatosis and nonalcoholic steatohepatitis: from pathogenesis to therapy. | 2016 | Details |
| A17651 | 27688653 | World J Gastroenterol | Iron and non-alcoholic fatty liver disease. | 2016 | Details |
| A17652 | 27688650 | World J Gastroenterol | Pediatric non-alcoholic fatty liver disease: Recent solutions, unresolved issues, and future research directions. | 2016 | Details |
| A17655 | 29416297 | Hippokratia | The adipokines in the pathogenesis and treatment of nonalcoholic fatty liver disease. | 2020 | Details |
| A17656 | 29327896 | Vojnosanit Pregl | Obesity and metabolic syndrome as risk factors for the development of non-alcoholic fatty liver disease as diagnosed by ultrasound. | 2016 | Details |
| A17657 | 29244927 | Patol Fiziol Eksp Ter | The impact of adipogenic diet on rats' tissue trace elements content. | 2018 | Details |
| A17658 | 27684605 | Atherosclerosis | Complex association of serum alanine aminotransferase with the risk of future cardiovascular disease in type 2 diabetes. | 2016 | Details |
| A17663 | 27679530 | J Biol Chem | Perilipin-2 Deletion Impairs Hepatic Lipid Accumulation by Interfering with Sterol Regulatory Element-binding Protein (SREBP) Activation and Altering the Hepatic Lipidome. | 2016 | Details |
| A17665 | 27678354 | World J Gastroenterol | Co-existence of non-alcoholic fatty liver disease and inflammatory bowel disease: A review article. | 2016 | Details |
| A17667 | 27677115 | Int J Surg Case Rep | Combined liver transplantation and sleeve gastrectomy for end-stage liver disease in a bariatric patient: First European case-report. | 2016 | Details |
| A17668 | 27672441 | BMC Obes | Hepatic steatosis, detected by hepatorenal index in ultrasonography, as a predictor of insulin resistance in obese subjects. | 2016 | Details |
| A17685 | 27659689 | Biol Open | Tree shrew (Tupaia belangeri chinensis), a novel non-obese animal model of non-alcoholic fatty liver disease. | 2016 | Details |
| A17687 | 27658772 | Gastroenterology | Estrogen Signals Through Peroxisome Proliferator-Activated Receptor-γ Coactivator 1α to Reduce Oxidative Damage Associated With Diet-Induced Fatty Liver Disease. | 2016 | Details |
| A17690 | 27656480 | J Clin Diagn Res | Comparative Effect of Insulin Sensitizers and Statin on Metabolic Profile and Ultrasonographical Score in Non Alcoholic Fatty Liver Disease. | 2016 | Details |
| A17703 | 27648154 | World J Hepatol | Hypolactasia is associated with insulin resistance in nonalcoholic steatohepatitis. | 2016 | Details |
| A17713 | 27639801 | Gastroenterology | An Intestinal Microbiota-Farnesoid X Receptor Axis Modulates Metabolic Disease. | 2016 | Details |
| A17718 | 27637587 | J Gastroenterol | Nonalcoholic fatty liver disease in Asia: emerging perspectives. | 2016 | Details |
| A17730 | 27633111 | Adv Nutr | Improvements in Metabolic Health with Consumption of Ellagic Acid and Subsequent Conversion into Urolithins: Evidence and Mechanisms. | 2016 | Details |
| A17733 | 27632189 | PLoS Comput Biol | A Computational Model of Hepatic Energy Metabolism: Understanding Zonated Damage and Steatosis in NAFLD. | 2016 | Details |
| A17734 | 27631178 | Arch Iran Med | Regression of Non-Alcoholic Fatty Liver by Vitamin D Supplement: A Double-Blind Randomized Controlled Clinical Trial. | 2016 | Details |
| A17735 | 27631137 | Diabetologia | The suppression of hepatic glucose production improves metabolism and insulin sensitivity in subcutaneous adipose tissue in mice. | 2016 | Details |
| A17738 | 27628583 | Endocrine | Serum fetuin B level increased in subjects of nonalcoholic fatty liver disease: a case-control study. | 2016 | Details |
| A17739 | 27628106 | Diabetologia | Hepatocyte glutathione peroxidase-1 deficiency improves hepatic glucose metabolism and decreases steatohepatitis in mice. | 2016 | Details |
| A17748 | 27621595 | Drug Des Devel Ther | The effects of the insulin resistance index on the virologic response to entecavir in patients with HBeAg-positive chronic hepatitis B and nonalcoholic fatty liver disease. | 2016 | Details |
| A17749 | 27621581 | World J Gastroenterol | Effects of different diets on intestinal microbiota and nonalcoholic fatty liver disease development. | 2016 | Details |
| A17758 | 27616599 | Sci Rep | Relationship between grip strength and newly diagnosed nonalcoholic fatty liver disease in a large-scale adult population. | 2016 | Details |
| A17768 | 27610012 | World J Gastroenterol | Metabolic aspects of adult patients with nonalcoholic fatty liver disease. | 2016 | Details |
| A17770 | 27609847 | BMJ Open | Associations between sitting time and non-alcoholic fatty liver diseases in Chinese male workers: a cross-sectional study. | 2016 | Details |
| A17773 | 27605877 | World J Gastroenterol | Metabolic complications in liver transplant recipients. | 2016 | Details |
| A17780 | 27600326 | J Hum Nutr Diet | Waist-to-height ratio is independently related to whole and central body fat, regardless of the waist circumference measurement protocol, in non-alcoholic fatty liver disease patients. | 2016 | Details |
| A17781 | 27599824 | J Hepatol | Sarcopenia is an independent risk factor for non-alcoholic steatohepatitis and significant fibrosis. | 2016 | Details |
| A17786 | 27594563 | Postepy Hig Med Dosw (Online) | New peptides players in metabolic disorders. | 2016 | Details |
| A17788 | 27593525 | Diabetes Obes Metab | Increased liver fat and glycogen stores after consumption of high versus low glycaemic index food: A randomized crossover study. | 2016 | Details |
| A17790 | 27589792 | Nutrients | Platycodon grandiflorus Root Extract Attenuates Body Fat Mass, Hepatic Steatosis and Insulin Resistance through the Interplay between the Liver and Adipose Tissue. | 2016 | Details |
| A17793 | 27586548 | Croat Med J | Conjugated linoleic acid improves glycemic response, lipid profile, and oxidative stress in obese patients with non-alcoholic fatty liver disease: a randomized controlled clinical trial. | 2016 | Details |
| A17800 | 27579785 | PLoS One | Influence of Ethnicity on the Accuracy of Non-Invasive Scores Predicting Non-Alcoholic Fatty Liver Disease. | 2016 | Details |
| A17802 | 27577854 | Am J Physiol Endocrinol Metab | Treatment of nonalcoholic fatty liver disease: role of AMPK. | 2016 | Details |
| A17806 | 27572914 | Sci Rep | Lack of association between SREBF-1c gene polymorphisms and risk of non-alcoholic fatty liver disease in a Chinese Han population. | 2016 | Details |
| A17814 | 27564402 | Expert Opin Pharmacother | Emerging and future therapies for nonalcoholic steatohepatitis in adults. | 2016 | Details |
| A17815 | 27563875 | Int J Mol Sci | Micronutrient Antioxidants and Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A17826 | 27553225 | FASEB J | Suppression of IGF binding protein-3 by palmitate promotes hepatic inflammatory responses. | 2016 | Details |
| A17829 | 27548822 | Dig Dis | Extrahepatic Diseases and NAFLD: The Triangular Relationship between NAFLD, Type 2-Diabetes and Dysbiosis. | 2016 | Details |
| A17830 | 27548720 | Dig Dis | Pathophysiology of Nonalcoholic Fatty Liver Disease: Lifestyle-Gut-Gene Interaction. | 2016 | Details |
| A17836 | 27547235 | Nutr Metab (Lond) | Assessment of Vitamin D status in a group of Egyptian children with non alcoholic fatty liver disease (multicenter study). | 2016 | Details |
| A17840 | 27545758 | Clin Res Hepatol Gastroenterol | Non-alcoholic fatty liver disease and flavonoids: Current perspectives. | 2016 | Details |