Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A43805 | 30835849 | J Food Sci | Extraction Technology Can Impose Influences on Peanut Oil Functional Quality: A Study to Investigate the Lipid Metabolism by Sprague-Dawley Rat Model. | 2019 | Details |
| A43816 | 30805080 | Oxid Med Cell Longev | Hydrogen Sulfide as a Novel Regulatory Factor in Liver Health and Disease. | 2019 | Details |
| A43840 | 30734689 | Endocr Metab Immune Disord Drug Targets | Silibinin Ameliorates Fructose-induced Lipid Accumulation and Activates Autophagy in HepG2 Cells. | 2019 | Details |
| A43846 | 30705513 | J Clin Biochem Nutr | 5-Aminolevulinic acid with ferrous iron improves early renal damage and hepatic steatosis in high fat diet-induced obese mice. | 2018 | Details |
| A43857 | 30670473 | J Lipid Res | Hepatocyte sortilin 1 knockout and treatment with a sortilin 1 inhibitor reduced plasma cholesterol in Western diet-fed mice. | 2019 | Details |
| A43866 | 30654277 | J Nutr Biochem | A mix of dietary fermentable fibers improves lipids handling by the liver of overfed minipigs. | 2018 | Details |
| A43875 | 30617219 | Diabetes | Perilipin 5 Deletion in Hepatocytes Remodels Lipid Metabolism and Causes Hepatic Insulin Resistance in Mice. | 2019 | Details |
| A43881 | 30609251 | Aging Cell | Reactive oxygen species-induced changes in glucose and lipid metabolism contribute to the accumulation of cholesterol in the liver during aging. | 2019 | Details |
| A43884 | 30576689 | Metabolism | Ectopic lipid deposition mediates insulin resistance in adipose specific 11β-hydroxysteroid dehydrogenase type 1 transgenic mice. | 2018 | Details |
| A43896 | 30541093 | Am J Clin Nutr | A 12-wk whole-grain wheat intervention protects against hepatic fat: the Graandioos study, a randomized trial in overweight subjects. | 2018 | Details |
| A43945 | 30379616 | Annu Rev Physiol | Phospholipid Remodeling in Physiology and Disease. | 2018 | Details |
| A43973 | 30265576 | FASEB J | Monoacylglycerol lipase deficiency affects diet-induced obesity, fat absorption, and feeding behavior in CB1 cannabinoid receptor-deficient mice. | 2018 | Details |
| A43978 | 30253173 | Toxicol Appl Pharmacol | Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces hepatic steatosis and endoplasmic reticulum stress by inducing nuclear factor erythroid-derived 2-related factor 2 nuclear translocation. | 2018 | Details |
| A43997 | 30188750 | Am J Physiol Gastrointest Liver Physiol | A rotating light cycle promotes weight gain and hepatic lipid storage in mice. | 2018 | Details |
| A44004 | 30160306 | J Physiol | Nutritional programming by maternal obesity: insights into the development of non-alcoholic fatty liver disease. | 2018 | Details |
| A44059 | 30014902 | Redox Biol | Polydatin prevents fructose-induced liver inflammation and lipid deposition through increasing miR-200a to regulate Keap1/Nrf2 pathway. | 2018 | Details |
| A44062 | 30001821 | J Hepatol | The role of Kupffer cells in hepatic iron and lipid metabolism. | 2018 | Details |
| A44112 | 29721506 | Biomed Res Int | Vildagliptin Can Alleviate Endoplasmic Reticulum Stress in the Liver Induced by a High Fat Diet. | 2018 | Details |
| A44126 | 29653253 | Biochim Biophys Acta Mol Cell Biol Lipids | Cholesterol and bile acid-mediated regulation of autophagy in fatty liver diseases and atherosclerosis. | 2018 | Details |
| A44136 | 29607540 | J Pineal Res | Melatonin improves insulin resistance and hepatic steatosis through attenuation of alpha-2-HS-glycoprotein. | 2018 | Details |
| A44161 | 29546310 | J Nutr | Corticosterone-Induced Lipogenesis Activation and Lipophagy Inhibition in Chicken Liver Are Alleviated by Maternal Betaine Supplementation. | 2018 | Details |
| A44194 | 29465311 | FASEB J | p32 regulates ER stress and lipid homeostasis by down-regulating GCS1 expression. | 2018 | Details |
| A44200 | 29442484 | Panminerva Med | Role of genetics and metabolism in non-alcoholic fatty liver disease. | 2018 | Details |
| A44212 | 29373534 | Nutrients | Betaine Supplementation Enhances Lipid Metabolism and Improves Insulin Resistance in Mice Fed a High-Fat Diet. | 2018 | Details |
| A44243 | 29257228 | Mol Med Rep | SREBP‑2 expression pattern contributes to susceptibility of Mongolian gerbils to hypercholesterolemia. | 2017 | Details |
| A44245 | 29254285 | Clin Mol Hepatol | Picroside II attenuates fatty acid accumulation in HepG2 cells via modulation of fatty acid uptake and synthesis. | 2017 | Details |
| A44260 | 29210655 | Curr Vasc Pharmacol | Editorial: Recent News on Statins for the Treatment of Non-Alcoholic Fatty Liver Disease/Non-Alcoholic Steatohepatitis. | 2018 | Details |
| A44262 | 29207074 | Mol Med Rep | Establishment of a novel hepatic steatosis cell model by Cas9/sgRNA-mediated DGKθ gene knockout. | 2017 | Details |
| A44279 | 29168825 | Nature | Disease progression: Divergent paths. | 2017 | Details |
| A44285 | 29160303 | Pharmacogenomics J | The PNPLA3 I148M variant is associated with transaminase elevations in type 2 diabetes patients treated with basal insulin peglispro. | 2017 | Details |
| A44344 | 28903485 | Toxicol Sci | Editor's Highlight: Mechanistic Toxicity Tests Based on an Adverse Outcome Pathway Network for Hepatic Steatosis. | 2017 | Details |
| A44353 | 28866102 | Life Sci | Liver steatosis in hypothalamic obese rats improves after duodeno-jejunal bypass by reduction in de novo lipogenesis pathway. | 2017 | Details |
| A44372 | 28795381 | Chin J Integr Med | Research progress on prevention and treatment of glucolipid metabolic disease with integrated traditional Chinese and Western medicine. | 2017 | Details |
| A44462 | 28548281 | J Intern Med | Adverse effects of fructose on cardiometabolic risk factors and hepatic lipid metabolism in subjects with abdominal obesity. | 2017 | Details |
| A44467 | 28534956 | Mol Med Rep | Effects of octreotide on hepatic glycogenesis in rats with high fat diet‑induced obesity. | 2017 | Details |
| A44499 | 28463859 | Curr Opin Lipidol | Adiponectin, lipids and atherosclerosis. | 2017 | Details |
| A44500 | 28459766 | Curr Opin Lipidol | Mode of action of berberine on lipid metabolism: a new-old phytochemical with clinical applications? | 2017 | Details |
| A44506 | 28447751 | Mol Med Rep | Deep sea water improves hypercholesterolemia and hepatic lipid accumulation through the regulation of hepatic lipid metabolic gene expression. | 2017 | Details |
| A44518 | 28385385 | Trends Endocrinol Metab | Deactivating Fatty Acids: Acyl-CoA Thioesterase-Mediated Control of Lipid Metabolism. | 2017 | Details |
| A44532 | 28323986 | J Clin Endocrinol Metab | Chronic Intranasal Insulin Does Not Affect Hepatic Lipids but Lowers Circulating BCAAs in Healthy Male Subjects. | 2017 | Details |
| A44533 | 28323964 | Endocrinology | Dysregulated Autophagy in Hepatocytes Promotes Bisphenol A-Induced Hepatic Lipid Accumulation in Male Mice. | 2017 | Details |
| A44550 | 28270440 | Am J Physiol Endocrinol Metab | Liver X receptor α induces 17β-hydroxysteroid dehydrogenase-13 expression through SREBP-1c. | 2017 | Details |
| A44570 | 28164071 | Ann Pediatr Endocrinol Metab | Transcriptional coordination of hepatic autophagy by nutrient-sensing nuclear receptor PPARα and FXR. | 2016 | Details |
| A44576 | 28133767 | Hepatology | The human longevity gene homolog INDY and interleukin-6 interact in hepatic lipid metabolism. | 2017 | Details |
| A44580 | 28105255 | World J Hepatol | PI3K/SHIP2/PTEN pathway in cell polarity and hepatitis C virus pathogenesis. | 2017 | Details |
| A44602 | 28027591 | Hepatology | TM6SF2 rs58542926 impacts lipid processing in liver and small intestine. | 2017 | Details |
| A44611 | 27981609 | Hepatology | The E3 ligase tripartite motif 8 targets TAK1 to promote insulin resistance and steatohepatitis. | 2017 | Details |
| A44614 | 27958883 | Antioxid Redox Signal | Glutaredoxin-1 Deficiency Causes Fatty Liver and Dyslipidemia by Inhibiting Sirtuin-1. | 2017 | Details |
| A44646 | 27822554 | mSystems | Farnesoid X Receptor Signaling Shapes the Gut Microbiota and Controls Hepatic Lipid Metabolism. | 2016 | Details |
| A44651 | 27516341 | Nat Rev Endocrinol | Endoplasmic reticulum proteostasis in hepatic steatosis. | 2016 | Details |
| A44655 | 27664470 | Am J Pathol | REV-ERBα Activates C/EBP Homologous Protein to Control Small Heterodimer Partner-Mediated Oscillation of Alcoholic Fatty Liver. | 2016 | Details |
| A44672 | 27707773 | J Mol Endocrinol | Additive effects of dexamethasone and palmitate on hepatic lipid accumulation and secretion. | 2016 | Details |
| A44673 | 27699898 | J Intern Med | Adipose tissue regulates insulin sensitivity: role of adipogenesis, de novo lipogenesis and novel lipids. | 2016 | Details |
| A44690 | 27732084 | Endocrinology | RABL2 Is Required for Hepatic Fatty Acid Homeostasis and Its Dysfunction Leads to Steatosis and a Diabetes-Like State. | 2016 | Details |
| A44706 | 27658392 | Diabetes | Ubiquitin Ligase COP1 Controls Hepatic Fat Metabolism by Targeting ATGL for Degradation. | 2016 | Details |
| A44732 | 27499712 | Gastroenterol Hepatol (N Y) | Metabolic Manifestations and Complications Associated With Chronic Hepatitis C Virus Infection. | 2016 | Details |
| A44774 | 27351453 | Hepatology | G-protein-coupled bile acid receptor plays a key role in bile acid metabolism and fasting-induced hepatic steatosis in mice. | 2016 | Details |
| A44775 | 27347902 | Compr Physiol | Functions of the Gallbladder. | 2016 | Details |
| A44799 | 27266041 | Nihon Naika Gakkai Zasshi | [Clinical Importance of Non-alcoholic Fatty Liver Diseases. Topics: IV. Relation of NAFLD with lifestyle-related disease including obesity, dyslipidemia and hypertension]. | 2016 | Details |
| A44801 | 27266039 | Nihon Naika Gakkai Zasshi | [Clinical Importance of Non-alcoholic Fatty Liver Diseases. Topics: II. Complexity in pathogenesis of nonalcoholic fatty liver disease]. | 2016 | Details |
| A44805 | 27262537 | Nutr Res | Mulberry ethanol extract attenuates hepatic steatosis and insulin resistance in high-fat diet-fed mice. | 2016 | Details |
| A44844 | 27097220 | PLoS One | Spaceflight Activates Lipotoxic Pathways in Mouse Liver. | 2016 | Details |
| A44872 | 27013659 | J Biol Chem | Liver MicroRNA-291b-3p Promotes Hepatic Lipogenesis through Negative Regulation of Adenosine 5'-Monophosphate (AMP)-activated Protein Kinase α1. | 2016 | Details |
| A44894 | 26936934 | J Leukoc Biol | The role of macrophages in obesity-driven chronic liver disease. | 2016 | Details |
| A44925 | 26780008 | Curr Opin Lipidol | Gene-based therapies in lipidology: current status and future challenges. | 2015 | Details |
| A44951 | 26637457 | J Virol | Hepatitis B Virus X Protein Induces Hepatic Steatosis by Enhancing the Expression of Liver Fatty Acid Binding Protein. | 2015 | Details |
| A44982 | 26530157 | Am J Physiol Endocrinol Metab | Advances in high-density lipoprotein physiology: surprises, overturns, and promises. | 2015 | Details |
| A45013 | 26443794 | J Lipid Res | Recent insights into the biological functions of liver fatty acid binding protein 1. | 2015 | Details |
| A45021 | 26419525 | Physiol Genomics | Gestation under chronic constant light leads to extensive gene expression changes in the fetal rat liver. | 2015 | Details |
| A45025 | 26396156 | Toxicol Sci | PCB126-Induced Disruption in Gluconeogenesis and Fatty Acid Oxidation Precedes Fatty Liver in Male Rats. | 2015 | Details |
| A45029 | 26382727 | Dig Liver Dis | Comment on "Resveratrol improves insulin resistance, glucose and lipid metabolism in patients with non-alcoholic fatty liver disease: A randomized controlled trial" by Shihui Chen et al. [Dig. Liver Dis. 2015;47:226-32]. | 2015 | Details |
| A45033 | 26376348 | Gastroenterology | Physiological Mechanisms of Weight Gain-Induced Steatosis in People With Obesity. | 2015 | Details |
| A45035 | 26364558 | Dig Liver Dis | Authors' reply to the comment on "Resveratrol improves insulin resistance, glucose and lipid metabolism in patients with non-alcoholic fatty liver disease: A randomized controlled trial" by Shihui Chen et al. [Dig. Liver Dis. 2015;47:226-32]. | 2015 | Details |
| A45039 | 26346354 | Nihon Shokakibyo Gakkai Zasshi | [Alcoholic liver disease and nonalcoholic fatty liver disease]. | 2015 | Details |
| A45043 | 26318761 | Pharmacol Res | Similarity between studies of dihydromyricetin and reservatrol for NAFLD. | 2015 | Details |
| A45047 | 26301251 | Biomed Res Int | Krill Oil Ameliorates Mitochondrial Dysfunctions in Rats Treated with High-Fat Diet. | 2015 | Details |
| A45048 | 26299475 | Pharmacol Res | Response to letter to the Editor: "Similarity between studies of dihydromyricetin and resveratrol for NAFLD". | 2015 | Details |
| A45095 | 26092479 | Life Sci | Improvement in the expression of hepatic genes involved in fatty acid metabolism in obese rats supplemented with taurine. | 2015 | Details |
| A45106 | 26063689 | Am J Clin Nutr | Retinoid X receptor: the forgotten partner in regulating lipid metabolism? | 2015 | Details |
| A45107 | 26061228 | J Med Food | Ethanol Extract of Persimmon Tree Leaves Improves Blood Circulation and Lipid Metabolism in Rats Fed a High-Fat Diet. | 2015 | Details |
| A45170 | 25838202 | Biochem Biophys Res Commun | Monoacylglycerol O-acyltransferase 1 is regulated by peroxisome proliferator-activated receptor γ in human hepatocytes and increases lipid accumulation. | 2015 | Details |
| A45214 | 25644347 | J Nutr | Lycopene and apo-10'-lycopenoic acid have differential mechanisms of protection against hepatic steatosis in β-carotene-9',10'-oxygenase knockout male mice. | 2014 | Details |
| A45240 | 25564660 | Proc Natl Acad Sci U S A | Insulin-independent regulation of hepatic triglyceride synthesis by fatty acids. | 2015 | Details |
| A45256 | 25514904 | J Lipid Res | KSRP is critical in governing hepatic lipid metabolism through controlling Per2 expression. | 2014 | Details |
| A45260 | 25501544 | Am J Physiol Gastrointest Liver Physiol | A high-fat diet modulates iron metabolism but does not promote liver fibrosis in hemochromatotic Hjv⁻/⁻ mice. | 2014 | Details |
| A45293 | 25357150 | J Med Food | Vigna nakashimae extract prevents hepatic steatosis in obese mice fed high-fat diets. | 2014 | Details |
| A45294 | 25350520 | Horm Metab Res | Nonalcoholic Fatty liver disease and hyperuricemia: a close relation with hepatic insulin resistance after nicotinic Acid treatment? | 2014 | Details |
| A45296 | 25308328 | Hepatology | Nitric oxide as a protector from nonalcoholic fatty liver disease. | 2015 | Details |
| A45301 | 25287814 | J Nutr Biochem | High-protein diets prevent steatosis and induce hepatic accumulation of monomethyl branched-chain fatty acids. | 2014 | Details |
| A45312 | 25230688 | Mol Med Rep | Liraglutide reduces lipid accumulation in steatotic L‑02 cells by enhancing autophagy. | 2014 | Details |
| A45319 | 25199052 | Lab Invest | Western diet in ApoE-LDLR double-deficient mouse model of atherosclerosis leads to hepatic steatosis, fibrosis, and tumorigenesis. | 2014 | Details |
| A45348 | 25079479 | J Pediatr Gastroenterol Nutr | Hepatic steatosis is prevalent in stillborns delivered to women with diabetes mellitus. | 2015 | Details |
| A45353 | 25073467 | Pharmacol Rev | Bile acid signaling in metabolic disease and drug therapy. | 2014 | Details |
| A45373 | 24927523 | Proc Natl Acad Sci U S A | TM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content. | 2014 | Details |
| A45381 | 24899303 | Nature | Lipids in health and disease. | 2014 | Details |
| A45383 | 24895043 | Endocrine | Basis of aggravated hepatic lipid metabolism by chronic stress in high-fat diet-fed rat. | 2014 | Details |
| A45388 | 24859739 | J Lipid Res | Enhanced synthesis of saturated phospholipids is associated with ER stress and lipotoxicity in palmitate treated hepatic cells. | 2014 | Details |
| A45406 | 24768697 | Toxicol Lett | Mitochondrial dysfunction in early life resulted from perinatal bisphenol A exposure contributes to hepatic steatosis in rat offspring. | 2014 | Details |
| A45409 | 24755648 | J Lipid Res | The IGF2 mRNA binding protein p62/IGF2BP2-2 induces fatty acid elongation as a critical feature of steatosis. | 2014 | Details |
| A45427 | 24680647 | Trends Immunol | The immunomodulating role of exercise in metabolic disease. | 2014 | Details |