Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A13506 | 29943733 | J Breath Res | The characterisation of hepatic mitochondrial function in patients with non-alcoholic fatty liver disease (NAFLD) using the 13C-ketoisocaproate breath test. | 2018 | Details |
| A13521 | 29935004 | Hepatol Res | Miglitol attenuates non-alcoholic steatohepatitis in diabetic patients. | 2018 | Details |
| A13525 | 29930810 | Biomed Rep | Efficacy of orlistat in non-alcoholic fatty liver disease: A systematic review and meta-analysis. | 2018 | Details |
| A13526 | 29930468 | World J Gastroenterol | Dynamic alterations in the gut microbiota and metabolome during the development of methionine-choline-deficient diet-induced nonalcoholic steatohepatitis. | 2018 | Details |
| A13527 | 29930001 | Arterioscler Thromb Vasc Biol | STK25 Regulates Cardiovascular Disease Progression in a Mouse Model of Hypercholesterolemia. | 2018 | Details |
| A13530 | 29929399 | Ann Med | The association of non-alcoholic fatty liver disease and atrial fibrillation: a review. | 2018 | Details |
| A13537 | 29924825 | PLoS One | Second harmonic generation microscopy provides accurate automated staging of liver fibrosis in patients with non-alcoholic fatty liver disease. | 2018 | Details |
| A13545 | 29920701 | Aliment Pharmacol Ther | Sarcopenia is associated with the risk of significant liver fibrosis in metabolically unhealthy subjects with chronic hepatitis B. | 2018 | Details |
| A13546 | 29920654 | Clin Exp Immunol | Immunotherapy with oral administration of humanized anti-CD3 monoclonal antibody: a novel gut-immune system-based therapy for metaflammation and NASH. | 2018 | Details |
| A13547 | 29920340 | Free Radic Biol Med | B2-Lymphocyte responses to oxidative stress-derived antigens contribute to the evolution of nonalcoholic fatty liver disease (NAFLD). | 2018 | Details |
| A13554 | 29913275 | Clin Gastroenterol Hepatol | Rates of and Factors Associated With Placebo Response in Trials of Pharmacotherapies for Nonalcoholic Steatohepatitis: Systematic Review and Meta-analysis. | 2018 | Details |
| A13564 | 29908362 | Clin Gastroenterol Hepatol | Magnetic Resonance vs Transient Elastography Analysis of Patients With Nonalcoholic Fatty Liver Disease: A Systematic Review and Pooled Analysis of Individual Participants. | 2018 | Details |
| A13565 | 29907965 | Hepatology | The Genetic Architecture of Diet-Induced Hepatic Fibrosis in Mice. | 2018 | Details |
| A13566 | 29906416 | Gastroenterology | Bioactive Lipid Species and Metabolic Pathways in Progression and Resolution of Nonalcoholic Steatohepatitis. | 2018 | Details |
| A13569 | 29903531 | J Pediatr | Pediatric Nonalcoholic Fatty Liver Disease in New York City: An Autopsy Study. | 2018 | Details |
| A13570 | 29903515 | Int J Cardiol | The nonalcoholic fatty liver disease (NAFLD) fibrosis score, cardiovascular risk stratification and a strategy for secondary prevention with ezetimibe. | 2018 | Details |
| A13573 | 29902522 | Cell Signal | Role of cAMP and phosphodiesterase signaling in liver health and disease. | 2018 | Details |
| A13575 | 29899440 | Am J Gastroenterol | Type and Pattern of Alcohol Consumption is Associated With Liver Fibrosis in Patients With Non-alcoholic Fatty Liver Disease. | 2018 | Details |
| A13585 | 29894414 | Transplantation | Risk Factors and Clinical Course for Liver Steatosis or Nonalcoholic Steatohepatitis After Living Donor Liver Transplantation. | 2019 | Details |
| A13586 | 29893699 | Ann Hepatol | Impact of Diabetes Mellitus and Insulin on Nonalcoholic Fatty Liver Disease in the Morbidly Obese. | 2019 | Details |
| A13587 | 29893698 | Ann Hepatol | Association Between Serum Hemoglobin Levels and Non Alcoholic Fatty Liver Disease in a Mexican Population. | 2019 | Details |
| A13588 | 29893235 | Lancet Gastroenterol Hepatol | Non-alcoholic fatty liver disease and the interface between primary and secondary care. | 2018 | Details |
| A13595 | 29890010 | J Gastroenterol Hepatol | Repeating measurements by transient elastography in non-alcoholic fatty liver disease patients with high liver stiffness. | 2018 | Details |
| A13596 | 29889226 | Inflamm Bowel Dis | Screening for Nonalcoholic Fatty Liver Disease in Inflammatory Bowel Diseases: A Cohort Study Using Transient Elastography. | 2019 | Details |
| A13602 | 29883718 | Biochim Biophys Acta Mol Basis Dis | Genetically modified mouse models to study hepatic neutral lipid mobilization. | 2018 | Details |
| A13604 | 29883377 | Nutrients | Circulating Phospholipid Patterns in NAFLD Patients Associated with a Combination of Metabolic Risk Factors. | 2018 | Details |
| A13605 | 29881818 | Hepatol Commun | Protein phosphatase 1 regulatory subunit 3B gene variation protects against hepatic fat accumulation and fibrosis in individuals at high risk of nonalcoholic fatty liver disease. | 2018 | Details |
| A13606 | 29881817 | Hepatol Commun | Metastasis-associated lung adenocarcinoma transcript 1 as a common molecular driver in the pathogenesis of nonalcoholic steatohepatitis and chronic immune-mediated liver damage. | 2018 | Details |
| A13610 | 29880653 | Eur Respir J | Increased liver stiffness in patients with severe sleep apnoea and metabolic comorbidities. | 2018 | Details |
| A13612 | 29878845 | Am J Physiol Gastrointest Liver Physiol | Lifestyle intervention for morbid obesity: effects on liver steatosis, inflammation, and fibrosis. | 2018 | Details |
| A13616 | 29873585 | Metab Syndr Relat Disord | NASH in Nondiabetic Endocrine Disorders. | 2018 | Details |
| A13617 | 29873275 | Int J Immunopathol Pharmacol | Hepatic artery resistive index as surrogate marker for fibrosis progression in NAFLD patients: A clinical perspective. | 2018 | Details |
| A13621 | 29870802 | Biochimie | Enhanced expression and distinctive characterization of a long-acting FGF21 and its potential to alleviate nonalcoholic steatohepatitis. | 2018 | Details |
| A13624 | 29869170 | Eur Radiol | Inter-sonographer reproducibility of quantitative ultrasound outcomes and shear wave speed measured in the right lobe of the liver in adults with known or suspected non-alcoholic fatty liver disease. | 2018 | Details |
| A13642 | 29858854 | Hormones (Athens) | Imaging of nonalcoholic fatty liver disease and its clinical utility. | 2018 | Details |
| A13643 | 29858843 | Hormones (Athens) | The effect of antidiabetic medications on non-alcoholic fatty liver disease (NAFLD). | 2018 | Details |
| A13644 | 29858567 | Nat Commun | Mucosal-associated invariant T cells are a profibrogenic immune cell population in the liver. | 2018 | Details |
| A13646 | 29858436 | Clin Med (Lond) | Non-alcoholic fatty liver disease. | 2018 | Details |
| A13648 | 29857146 | Clin Gastroenterol Hepatol | Evaluations of Lifestyle, Dietary, and Pharmacologic Treatments for Pediatric Nonalcoholic Fatty Liver Disease: A Systematic Review. | 2018 | Details |
| A13649 | 29856896 | Histopathology | Extracellular matrix components indicate remodelling activity in different fibrosis stages of human non-alcoholic fatty liver disease. | 2018 | Details |
| A13651 | 29855729 | EJNMMI Res | Evaluation of hepatic integrin αvβ3 expression in non-alcoholic steatohepatitis (NASH) model mouse by 18F-FPP-RGD2 PET. | 2018 | Details |
| A13653 | 29855033 | Histol Histopathol | Early effects of high-fat diet, extra-virgin olive oil and vitamin D in a sedentary rat model of non-alcoholic fatty liver disease. | 2018 | Details |
| A13661 | 29851153 | J Gastroenterol Hepatol | Burden of non-alcoholic fatty liver disease in Australia. | 2018 | Details |
| A13666 | 29848284 | Microrna | Serum miR-29a and miR-122 as Potential Biomarkers for Non-Alcoholic Fatty Liver Disease (NAFLD). | 2018 | Details |
| A13668 | 29847555 | PLoS One | Gemcabene downregulates inflammatory, lipid-altering and cell-signaling genes in the STAM™ model of NASH. | 2018 | Details |
| A13676 | 29844879 | Oncotarget | Clinical application of angiotensin receptor blockers in patients with non-alcoholic fatty liver disease: a systematic review and meta-analysis. | 2018 | Details |
| A13677 | 29844588 | Nat Rev Gastroenterol Hepatol | Noninvasive biomarkers in NAFLD and NASH - current progress and future promise. | 2018 | Details |
| A13682 | 29843404 | Medicines (Basel) | Mechanistic Potential and Therapeutic Implications of Cannabinoids in Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A13700 | 29802399 | Sci Rep | Obeticholic acid protects against hepatocyte death and liver fibrosis in a murine model of nonalcoholic steatohepatitis. | 2018 | Details |
| A13701 | 29802129 | Diabetes | Production of Elastin-Derived Peptides Contributes to the Development of Nonalcoholic Steatohepatitis. | 2018 | Details |
| A13705 | 29799837 | PLoS One | Elevated Nrf-2 responses are insufficient to mitigate protein carbonylation in hepatospecific PTEN deletion mice. | 2018 | Details |
| A13707 | 29799476 | Children (Basel) | Alanine Aminotransferase as a Monitoring Biomarker in Children with Nonalcoholic Fatty Liver Disease: A Secondary Analysis Using TONIC Trial Data. | 2018 | Details |
| A13711 | 29797393 | Liver Int | Leucocyte telomere shortening is associated with nonalcoholic fatty liver disease-related advanced fibrosis. | 2018 | Details |
| A13716 | 29794735 | Medicine (Baltimore) | Diagnostic performance of magnetic resonance technology in detecting steatosis or fibrosis in patients with nonalcoholic fatty liver disease: A meta-analysis. | 2018 | Details |
| A13721 | 29792584 | J Dev Orig Health Dis | Neonatal intake of oleanolic acid attenuates the subsequent development of high fructose diet-induced non-alcoholic fatty liver disease in rats. | 2018 | Details |
| A13728 | 29787859 | Contemp Clin Trials | Design and rationale of the INSYTE study: A randomised, placebo controlled study to test the efficacy of a synbiotic on liver fat, disease biomarkers and intestinal microbiota in non-alcoholic fatty liver disease. | 2018 | Details |
| A13733 | 29785393 | Psoriasis (Auckl) | Monitoring methotrexate-induced liver fibrosis in patients with psoriasis: utility of transient elastography. | 2018 | Details |
| A13734 | 29785151 | Clujul Med | Non-alcoholic fatty liver disease: an update on diagnosis. | 2018 | Details |
| A13744 | 29779170 | Eur J Nutr | Histological improvement of non-alcoholic steatohepatitis with a prebiotic: a pilot clinical trial. | 2018 | Details |
| A13745 | 29779083 | Dig Dis Sci | Identifying Nonalcoholic Fatty Liver Disease Advanced Fibrosis in the Veterans Health Administration. | 2018 | Details |
| A13746 | 29778532 | Biochem Biophys Res Commun | Non-alcoholic fatty liver disease: Insights from sphingolipidomics. | 2018 | Details |
| A13754 | 29773783 | Am J Case Rep | Cholesteryl Ester Storage Disease: Fatal Outcome without Causal Therapy in a Female Patient with the Preventable Sequelae of Progressive Liver Disease after Many Years of Mild Symptoms. | 2018 | Details |
| A13769 | 29765460 | Arch Med Sci | The role of intestinal microbiota in the pathogenesis of NAFLD: starting points for intervention. | 2016 | Details |
| A13776 | 29762096 | Radiology | US Time-Harmonic Elastography: Detection of Liver Fibrosis in Adolescents with Extreme Obesity with Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A13777 | 29761652 | Pediatr Obes | Vitamin D status and associated genetic polymorphisms in a cohort of UK children with non-alcoholic fatty liver disease. | 2018 | Details |
| A13783 | 29760499 | Sci Rep | Hepatic stellate cells secrete Ccl5 to induce hepatocyte steatosis. | 2018 | Details |
| A13786 | 29758334 | J Hepatol | Genetic inactivation of Nrf2 prevents clonal expansion of initiated cells in a nutritional model of rat hepatocarcinogenesis. | 2018 | Details |
| A13791 | 29753678 | Mol Metab | Deficiency of fibroblast growth factor 21 (FGF21) promotes hepatocellular carcinoma (HCC) in mice on a long term obesogenic diet. | 2018 | Details |
| A13792 | 29752404 | J Biol Chem | Low-density lipoprotein receptor-related protein-1 dysfunction synergizes with dietary cholesterol to accelerate steatohepatitis progression. | 2018 | Details |
| A13793 | 29752170 | J Pediatr | Treating Obstructive Sleep Apnea and Chronic Intermittent Hypoxia Improves the Severity of Nonalcoholic Fatty Liver Disease in Children. | 2018 | Details |
| A13797 | 29751074 | Food Chem Toxicol | Effects of high fructose intake on liver injury progression in high fat diet induced fatty liver disease in ovariectomized female mice. | 2018 | Details |
| A13798 | 29750881 | Physiol Res | Pathophysiological characteristics of non-alcoholic steatohepatitis-like changes in cholesterol-loaded type 2 diabetic rats. | 2018 | Details |
| A13799 | 29749571 | J Gastroenterol | Hepatic IRS1 and ß-catenin expression is associated with histological progression and overt diabetes emergence in NAFLD patients. | 2018 | Details |
| A13808 | 29744597 | J Gastroenterol | The novel cutoff points for the FIB4 index categorized by age increase the diagnostic accuracy in NAFLD: a multi-center study. | 2018 | Details |
| A13815 | 29743925 | Evid Based Complement Alternat Med | Gynostemma pentaphyllum Attenuates the Progression of Nonalcoholic Fatty Liver Disease in Mice: A Biomedical Investigation Integrated with In Silico Assay. | 2018 | Details |
| A13822 | 29740791 | Paediatr Drugs | Nonalcoholic Fatty Liver Disease in Children: Not a Small Matter. | 2018 | Details |
| A13823 | 29740166 | Nat Rev Gastroenterol Hepatol | Triggering and resolution of inflammation in NASH. | 2018 | Details |
| A13825 | 29739707 | Int J Cardiol | Non-alcoholic fatty liver disease and increased risk of all-cause mortality in elderly patients admitted for acute heart failure. | 2018 | Details |
| A13829 | 29735977 | Cell Mol Immunol | Increased Tim-3 expression alleviates liver injury by regulating macrophage activation in MCD-induced NASH mice. | 2018 | Details |
| A13831 | 29735799 | Ann Hepatol | Therapeutic Effect of HGF on NASH Mice Through HGF/c-Met and JAK2-STAT3 Signalling Pathway. | 2018 | Details |
| A13838 | 29733831 | Gastroenterology | Fibrosis Severity as a Determinant of Cause-Specific Mortality in Patients With Advanced Nonalcoholic Fatty Liver Disease: A Multi-National Cohort Study. | 2018 | Details |
| A13853 | 29725976 | Obes Surg | Impact of Weight Regain on the Evolution of Non-alcoholic Fatty Liver Disease After Roux-en-Y Gastric Bypass: a 3-Year Follow-up. | 2018 | Details |
| A13873 | 29717162 | Sci Rep | Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice. | 2018 | Details |
| A13874 | 29715085 | Anticancer Res | Chemerin in a Mouse Model of Non-alcoholic Steatohepatitis and Hepatocarcinogenesis. | 2018 | Details |
| A13878 | 29713129 | World J Gastroenterol | Nonalcoholic steatohepatitis severity is defined by a failure in compensatory antioxidant capacity in the setting of mitochondrial dysfunction. | 2018 | Details |
| A13879 | 29713125 | World J Gastroenterol | Beneficial effects of naringenin in liver diseases: Molecular mechanisms. | 2018 | Details |
| A13881 | 29712495 | Int J Biol Markers | Development of a novel diagnostic algorithm to predict NASH in HCV-positive patients. | 2018 | Details |
| A13886 | 29709653 | Life Sci | Oleic acid protects saturated fatty acid mediated lipotoxicity in hepatocytes and rat of non-alcoholic steatohepatitis. | 2018 | Details |
| A13891 | 29705265 | Clin Gastroenterol Hepatol | Acetyl-CoA Carboxylase Inhibitor GS-0976 for 12 Weeks Reduces Hepatic De Novo Lipogenesis and Steatosis in Patients With Nonalcoholic Steatohepatitis. | 2018 | Details |
| A13892 | 29705261 | Clin Gastroenterol Hepatol | Vibration-Controlled Transient Elastography to Assess Fibrosis and Steatosis in Patients With Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A13895 | 29705030 | Dig Liver Dis | Adherence to quality criteria improves concordance between transient elastography and ElastPQ for liver stiffness assessment-A multicenter retrospective study. | 2018 | Details |
| A13900 | 29702590 | Int J Mol Sci | Insulin-Like Growth Factor (IGF) System in Liver Diseases. | 2018 | Details |
| A13904 | 29700094 | Clin Med (Lond) | Genetics of alcoholic liver disease and non-alcoholic steatohepatitis. | 2018 | Details |
| A13914 | 29696816 | J Dig Dis | Deletion of Smad4 reduces hepatic inflammation and fibrogenesis during nonalcoholic steatohepatitis progression. | 2018 | Details |
| A13919 | 29692949 | J Clin Imaging Sci | Laboratory Tests, Liver Vessels Color Doppler Sonography, and FibroScan Findings in Patients with Nonalcoholic Fatty Liver Disease: An Observation Study. | 2018 | Details |
| A13921 | 29690903 | J Transl Med | CCL20 is up-regulated in non-alcoholic fatty liver disease fibrosis and is produced by hepatic stellate cells in response to fatty acid loading. | 2018 | Details |
| A13926 | 29686467 | World J Gastroenterol | Multiomics biomarkers for the prediction of nonalcoholic fatty liver disease severity. | 2018 | Details |
| A13927 | 29686465 | World J Gastroenterol | Ultrasound findings in autoimmune hepatitis. | 2018 | Details |
| A13933 | 29682571 | Biomed Res Int | The Association of Gut Microbiota with Nonalcoholic Steatohepatitis in Thais. | 2018 | Details |
| A13936 | 29680867 | J Gastroenterol | Evaluation of ballooned hepatocytes as a risk factor for future progression of fibrosis in patients with non-alcoholic fatty liver disease. | 2018 | Details |