Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A25413 | 21878559 | Drug Metab Dispos | Variations in ATP-binding cassette transporter regulation during the progression of human nonalcoholic fatty liver disease. | 2011 | Details |
| A25422 | 21873555 | FASEB J | Kupffer cell depletion prevents but has no therapeutic effect on metabolic and inflammatory changes induced by a high-fat diet. | 2011 | Details |
| A25430 | 21855538 | Exp Mol Pathol | Elevated systemic monocyte chemoattractrant protein-1 in hepatic steatosis without significant hepatic inflammation. | 2011 | Details |
| A25456 | 21813474 | Gut | Pharmacological inhibition of the chemokine CCL2 (MCP-1) diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury. | 2011 | Details |
| A25470 | 21797822 | Clin Sci (Lond) | Role of Toll-like receptors in liver health and disease. | 2011 | Details |
| A25475 | 21793029 | Hepatology | Apolipoprotein CIII overexpressing mice are predisposed to diet-induced hepatic steatosis and hepatic insulin resistance. | 2011 | Details |
| A25476 | 21791204 | Exp Mol Pathol | MMP-9 activity is increased by adiponectin in primary human hepatocytes but even negatively correlates with serum adiponectin in a rodent model of non-alcoholic steatohepatitis. | 2011 | Details |
| A25478 | 21788761 | J Pediatr Gastroenterol Nutr | Ultrasonographic quantitative estimation of hepatic steatosis in children With NAFLD. | 2011 | Details |
| A25480 | 21787451 | Br J Nutr | Protective effects of fractional extracts from Panellus serotinus on non-alcoholic fatty liver disease in obese, diabetic db/db mice. | 2011 | Details |
| A25519 | 21748768 | Hepatology | Dysregulation of the unfolded protein response in db/db mice with diet-induced steatohepatitis. | 2011 | Details |
| A25529 | 21744131 | Obes Surg | Association of obestatin, ghrelin, and inflammatory cytokines in obese patients with non-alcoholic fatty liver disease. | 2011 | Details |
| A25540 | 21734391 | Dig Dis | Pathophysiology of non-alcoholic steatohepatitis and basis for treatment. | 2011 | Details |
| A25548 | 21725996 | Hepatology | Inflammation-associated interleukin-6/signal transducer and activator of transcription 3 activation ameliorates alcoholic and nonalcoholic fatty liver diseases in interleukin-10-deficient mice. | 2011 | Details |
| A25562 | 21709958 | Arq Gastroenterol | Hepatic and biochemical repercussions of a polyunsaturated fat-rich hypercaloric and hyperlipidic diet in Wistar rats. | 2012 | Details |
| A25570 | 21703208 | J Hepatol | DSS induced colitis increases portal LPS levels and enhances hepatic inflammation and fibrogenesis in experimental NASH. | 2011 | Details |
| A25577 | 21700865 | Science | Human fatty liver disease: old questions and new insights. | 2011 | Details |
| A25582 | 21690266 | J Lipid Res | Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice. | 2011 | Details |
| A25597 | 21671974 | Scand J Immunol | Resistin is associated with breach of tolerance and anti-nuclear antibodies in patients with hepatobiliary inflammation. | 2011 | Details |
| A25607 | 21655948 | Dig Dis Sci | Mechanisms linking nonalcoholic fatty liver disease with coronary artery disease. | 2011 | Details |
| A25619 | 21635548 | APMIS | Microvesicular fat, inter cellular adhesion molecule-1 and regulatory T-lymphocytes are of importance for the inflammatory process in livers with non-alcoholic steatohepatitis. | 2011 | Details |
| A25634 | 21620948 | Toxicol In Vitro | Cellular glutathione in fatty liver in vitro models. | 2011 | Details |
| A25641 | 21612059 | Vnitr Lek | [Steatosis and steatohepatitis in diabetic patient]. | 2011 | Details |
| A25653 | 21587068 | Curr Opin Clin Nutr Metab Care | The 5-lipoxygenase/leukotriene pathway in obesity, insulin resistance, and fatty liver disease. | 2011 | Details |
| A25666 | 21564529 | Am J Transplant | Should metformin be our antiglycemic agent of choice post-transplantation? | 2011 | Details |
| A25668 | 21563774 | J Proteome Res | A proton nuclear magnetic resonance metabonomics approach for biomarker discovery in nonalcoholic fatty liver disease. | 2011 | Details |
| A25686 | 21545576 | Br J Pharmacol | Resistin: functional roles and therapeutic considerations for cardiovascular disease. | 2012 | Details |
| A25688 | 21543212 | J Nutr Biochem | Green tea extract protects against nonalcoholic steatohepatitis in ob/ob mice by decreasing oxidative and nitrative stress responses induced by proinflammatory enzymes. | 2011 | Details |
| A25692 | 21537547 | Arq Gastroenterol | Methionine- and choline-deficient diet induces hepatic changes characteristic of non-alcoholic steatohepatitis. | 2011 | Details |
| A25699 | 21525818 | Med Sci Monit | SIRT1 as a potential therapeutic target for treatment of nonalcoholic fatty liver disease. | 2011 | Details |
| A25715 | 21514287 | Clin Chim Acta | The role of oxidative stress in non-alcoholic steatohepatitis. | 2011 | Details |
| A25719 | 21509233 | Sultan Qaboos Univ Med J | Non-Alcoholic Fatty Liver Disease (NAFLD) - Is it an Emerging Risk Factor for Coronary Artery Disease?: Preliminary study in a local Indian population. | 2010 | Details |
| A25720 | 21508207 | J Nutr | Rutin attenuates metabolic changes, nonalcoholic steatohepatitis, and cardiovascular remodeling in high-carbohydrate, high-fat diet-fed rats. | 2011 | Details |
| A25739 | 21492876 | J Surg Res | The effect of hepatic ischemia reperfusion injury in a murine model of nonalcoholic steatohepatitis. | 2011 | Details |
| A25741 | 21488946 | J Gastroenterol Hepatol | Inflammatory stress exacerbates hepatic cholesterol accumulation via increasing cholesterol uptake and de novo synthesis. | 2011 | Details |
| A25755 | 21477300 | Lipids Health Dis | Systematic review on the treatment of pentoxifylline in patients with non-alcoholic fatty liver disease. | 2011 | Details |
| A25774 | 21474829 | Arterioscler Thromb Vasc Biol | Peroxisome proliferator-activated receptor-alpha gene level differently affects lipid metabolism and inflammation in apolipoprotein E2 knock-in mice. | 2011 | Details |
| A25781 | 21463337 | Alcohol Clin Exp Res | A new model of interactive effects of alcohol and high-fat diet on hepatic fibrosis. | 2011 | Details |
| A25800 | 21446920 | Clin Sci (Lond) | Methionine and protein metabolism in non-alcoholic steatohepatitis: evidence for lower rate of transmethylation of methionine. | 2011 | Details |
| A25802 | 21442288 | Virchows Arch | Histopathological diagnosis of non-alcoholic and alcoholic fatty liver disease. | 2011 | Details |
| A25808 | 21439567 | Atherosclerosis | Diet, commensals and the intestine as sources of pathogen-associated molecular patterns in atherosclerosis, type 2 diabetes and non-alcoholic fatty liver disease. | 2011 | Details |
| A25822 | 21426695 | Zhonghua Er Ke Za Zhi | [Metformin prevents non-alcoholic fatty liver disease in rats: role of phospholipase A2/lysophosphatidylcholine lipoapoptosis pathway in hepatocytes]. | 2011 | Details |
| A25838 | 21410952 | J Inflamm (Lond) | Inflammatory Signals shift from adipose to liver during high fat feeding and influence the development of steatohepatitis in mice. | 2011 | Details |
| A25845 | 21401612 | J Pharm Pharmacol | Hepatoprotective effects of geniposide in a rat model of nonalcoholic steatohepatitis. | 2011 | Details |
| A25864 | 21381068 | Hepatology | Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease. | 2011 | Details |
| A25876 | 21364120 | Am J Physiol Endocrinol Metab | Rhein ameliorates fatty liver disease through negative energy balance, hepatic lipogenic regulation, and immunomodulation in diet-induced obese mice. | 2011 | Details |
| A25882 | 21356258 | J Hepatol | Intravenous administration of multipotent stromal cells prevents the onset of non-alcoholic steatohepatitis in obese mice with metabolic syndrome. | 2011 | Details |
| A25884 | 21354232 | J Hepatol | Lack of interleukin-1α or interleukin-1β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice. | 2011 | Details |
| A25886 | 21353887 | Vitam Horm | Activin A in nonalcoholic fatty liver disease. | 2011 | Details |
| A25888 | 21351214 | Inflamm Bowel Dis | Changing shape of disease: nonalcoholic fatty liver disease in Crohn's disease-a case series and review of the literature. | 2011 | Details |
| A25894 | 21348181 | G Ital Cardiol (Rome) | [Non-alcoholic fatty liver disease: a new challenge for cardiologists]. | 2010 | Details |
| A25897 | 21346097 | J Nutr | PPARalpha expression protects male mice from high fat-induced nonalcoholic fatty liver. | 2011 | Details |
| A25925 | 21320636 | Int Immunopharmacol | Anti-inflammatory effect of genistein on non-alcoholic steatohepatitis rats induced by high fat diet and its potential mechanisms. | 2011 | Details |
| A25929 | 21317853 | G Ital Dermatol Venereol | Psoriasis: comorbidities and associations. | 2011 | Details |
| A25939 | 21292470 | J Nutr Biochem | Probiotics as an emerging therapeutic strategy to treat NAFLD: focus on molecular and biochemical mechanisms. | 2011 | Details |
| A25947 | 21280192 | Liver Transpl | Endoplasmic reticulum stress is a mediator of posttransplant injury in severely steatotic liver allografts. | 2011 | Details |
| A25971 | 21251450 | Acta Dermatovenerol Croat | Metabolic comorbidities and psoriasis. | 2010 | Details |
| A25976 | 21246004 | World J Gastroenterol | Potential efficacy of ginger as a natural supplement for nonalcoholic fatty liver disease. | 2011 | Details |
| A25977 | 21245286 | Drug Metab Dispos | Hepatic pharmacokinetics of cationic drugs in a high-fat emulsion-induced rat model of nonalcoholic steatohepatitis. | 2011 | Details |
| A25988 | 21233280 | Am J Physiol Gastrointest Liver Physiol | Deficiency in myeloid differentiation factor-2 and toll-like receptor 4 expression attenuates nonalcoholic steatohepatitis and fibrosis in mice. | 2011 | Details |
| A25992 | 21227598 | Pathol Res Pract | Experimental study of non-alcoholic fatty liver disease (NAFLD) on a model of starving chickens: is generalization of steatosis accompanied by fibrosis of the liver tissue? | 2011 | Details |
| A25996 | 21225497 | Pol J Pathol | Liver visfatin expression in morbidly obese patients with nonalcoholic fatty liver disease undergoing bariatric surgery. | 2010 | Details |
| A25999 | 21224501 | J Physiol Pharmacol | The pilot study of 3-month course of melatonin treatment of patients with nonalcoholic steatohepatitis: effect on plasma levels of liver enzymes, lipids and melatonin. | 2010 | Details |
| A26004 | 21218508 | Diabetes Metab Res Rev | Metformin and atorvastatin combination further protect the liver in type 2 diabetes with hyperlipidaemia. | 2011 | Details |
| A26005 | 21216282 | Biochim Biophys Acta | Lipotoxicity and steatohepatitis in an overfed mouse model for non-alcoholic fatty liver disease. | 2011 | Details |
| A26024 | 22568272 | Rom J Intern Med | Depression and anxiety in nonalcoholic steatohepatitis: is there any association? | 2011 | Details |
| A26025 | 22566839 | Front Immunol | New insights into the role of macrophages in adipose tissue inflammation and Fatty liver disease: modulation by endogenous omega-3 Fatty Acid-derived lipid mediators. | 2011 | Details |
| A26031 | 21184788 | J Hepatol | Impact of artificial sunlight therapy on the progress of non-alcoholic fatty liver disease in rats. | 2010 | Details |
| A26038 | 21180596 | Therap Adv Gastroenterol | Treatment options for nonalcoholic fatty liver disease. | 2010 | Details |
| A26044 | 21168460 | J Hepatol | Early interplay of intra-hepatic iron and insulin resistance in children with non-alcoholic fatty liver disease. | 2010 | Details |
| A26058 | 21155004 | World J Gastroenterol | Pro12Ala polymorphism of the peroxisome proliferator-activated receptor γ2 in patients with fatty liver diseases. | 2010 | Details |
| A26061 | 21150132 | Drug Metab Pharmacokinet | Progression of alcoholic and non-alcoholic steatohepatitis: common metabolic aspects of innate immune system and oxidative stress. | 2010 | Details |
| A26066 | 21145850 | J Hepatol | Risk of chronic kidney disease in patients with non-alcoholic fatty liver disease: is there a link? | 2010 | Details |
| A26071 | 21145829 | J Hepatol | Oleuropein attenuates hepatic steatosis induced by high-fat diet in mice. | 2010 | Details |
| A26072 | 21145828 | J Hepatol | A randomized controlled trial of high-dose ursodesoxycholic acid for nonalcoholic steatohepatitis. | 2010 | Details |
| A26073 | 21145823 | J Hepatol | Galectin-3 ablation protects mice from diet-induced NASH: a major scavenging role for galectin-3 in liver. | 2010 | Details |
| A26074 | 21145819 | J Hepatol | Overexpression of the IGF2-mRNA binding protein p62 in transgenic mice induces a steatotic phenotype. | 2010 | Details |
| A26090 | 21122807 | Toxicol Appl Pharmacol | Reduction of liver fructokinase expression and improved hepatic inflammation and metabolism in liquid fructose-fed rats after atorvastatin treatment. | 2010 | Details |
| A26093 | 21115542 | Gut | Nor-ursodeoxycholic acid reverses hepatocyte-specific nemo-dependent steatohepatitis. | 2010 | Details |
| A26113 | 21073649 | Liver Int | Angiogenesis in chronic liver disease and its complications. | 2010 | Details |
| A26117 | 21072890 | World J Gastroenterol | Pediatric nonalcoholic fatty liver disease: overview with emphasis on histology. | 2010 | Details |
| A26118 | 21071306 | Orv Hetil | [Fatty liver and global cardiometabolic risk]. | 2010 | Details |
| A26126 | 21055684 | Clin Liver Dis | Nonalcoholic fatty liver disease. | 2010 | Details |
| A26128 | 21054517 | J Gastroenterol Hepatol | Sophocarpine alleviates non-alcoholic steatohepatitis in rats. | 2011 | Details |
| A26131 | 21045794 | Nat Rev Gastroenterol Hepatol | The role of the gut microbiota in nonalcoholic fatty liver disease. | 2010 | Details |
| A26133 | 21044016 | Curr Vasc Pharmacol | Novel role of NPC1L1 in the regulation of hepatic metabolism: potential contribution of ezetimibe in NAFLD/NASH treatment. | 2011 | Details |
| A26135 | 21042596 | PLoS One | Hepatic expression patterns of inflammatory and immune response genes associated with obesity and NASH in morbidly obese patients. | 2010 | Details |
| A26137 | 21042023 | Digestion | Obesity affects the liver - the link between adipocytes and hepatocytes. | 2010 | Details |
| A26138 | 21040936 | Metabolism | The association between the metabolic syndrome and alanine amino transferase is mediated by insulin resistance via related metabolic intermediates (the Cohort on Diabetes and Atherosclerosis Maastricht [CODAM] study). | 2010 | Details |
| A26175 | 20955971 | Best Pract Res Clin Gastroenterol | Nonalcoholic fatty liver disease. | 2010 | Details |
| A26182 | 20943080 | Zhonghua Gan Zang Bing Za Zhi | [The role of heme oxygenase-1 in non-alcoholic steatohepatitis]. | 2010 | Details |
| A26187 | 20939105 | World J Gastroenterol | Hepatic steatosis, low-grade chronic inflammation and hormone/growth factor/adipokine imbalance. | 2010 | Details |
| A26188 | 20939104 | World J Gastroenterol | Fat: a matter of disturbance for the immune system. | 2010 | Details |
| A26196 | 20929443 | Clin Sci (Lond) | Enhanced expression of pro-inflammatory mediators and liver X-receptor-regulated lipogenic genes in non-alcoholic fatty liver disease and hepatitis C. | 2011 | Details |
| A26208 | 20887718 | Clin Chim Acta | Pro-inflammatory and atherogenic circulating factors in non-alcoholic fatty liver disease associated to metabolic syndrome. | 2010 | Details |
| A26224 | 20869214 | Exp Toxicol Pathol | Swimming training beneficial effects in a mice model of nonalcoholic fatty liver disease. | 2010 | Details |
| A26229 | 20862821 | Isr Med Assoc J | Serum inflammatory markers in overweight children and adolescents with non-alcoholic fatty liver disease. | 2010 | Details |
| A26231 | 20858684 | Diabetes | Adipose tissue dysfunction signals progression of hepatic steatosis towards nonalcoholic steatohepatitis in C57BL/6 mice. | 2010 | Details |
| A26243 | 20845385 | Biotechnol J | Hepatoprotective effect of oleuropein in mice: mechanisms uncovered by gene expression profiling. | 2010 | Details |
| A26245 | 20842602 | Swiss Med Wkly | Multifaceted roles of peroxisome proliferator-activated receptors (PPARs) at the cellular and whole organism levels. | 2010 | Details |
| A26250 | 20840346 | J Eur Acad Dermatol Venereol | Psoriasis and non-alcoholic fatty liver disease. | 2010 | Details |