Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Article ID | PMID | Source | Title | Publish Year | |
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A11897 | 30689995 | Eur J Pharmacol | Betaine modulates oxidative stress, inflammation, apoptosis, autophagy, and Akt/mTOR signaling in methionine-choline deficiency-induced fatty liver disease. | 2019 | Details |
A11925 | 30680007 | Exp Ther Med | Effects of liver function, insulin resistance and inflammatory factors on vascular endothelial dilation function and prognosis of coronary heart disease patients complicated with NAFLD. | 2018 | Details |
A11937 | 30673851 | Med Mol Morphol | The therapeutic effects of resveratrol on hepatic steatosis in high-fat diet-induced obese mice by improving oxidative stress, inflammation and lipid-related gene transcriptional expression. | 2019 | Details |
A11945 | 30671426 | Front Pediatr | Novel Ultrasonographic Fatty Liver Indicator Can Predict Hepatitis in Children With Non-alcoholic Fatty Liver Disease. | 2019 | Details |
A11946 | 30671174 | Oxid Med Cell Longev | Modulation of the Gut Microbiota in Rats by Hugan Qingzhi Tablets during the Treatment of High-Fat-Diet-Induced Nonalcoholic Fatty Liver Disease. | 2018 | Details |
A11958 | 30668424 | Phytomedicine | Lycopus lucidus Turcz. ex Benth. Attenuates free fatty acid-induced steatosis in HepG2 cells and non-alcoholic fatty liver disease in high-fat diet-induced obese mice. | 2018 | Details |
A11975 | 30660761 | Diabetes Metab | Insulin resistance and NAFLD: Relationship with intrahepatic iron and serum TNF-α using 1H MR spectroscopy and MRI. | 2019 | Details |
A12051 | 30622377 | World J Gastroenterol | Mismatched effects of receptor interacting protein kinase-3 on hepatic steatosis and inflammation in non-alcoholic fatty liver disease. | 2018 | Details |
A12063 | 30618733 | Front Pharmacol | Geniposide and Chlorogenic Acid Combination Ameliorates Non-alcoholic Steatohepatitis Involving the Protection on the Gut Barrier Function in Mouse Induced by High-Fat Diet. | 2018 | Details |
A12152 | 30580553 | Crit Rev Food Sci Nutr | n-3 Polyunsaturated fatty acids for the management of alcoholic liver disease: A critical review. | 2018 | Details |
A12165 | 30576936 | Biomed Pharmacother | Sodium tanshinone IIA sulfonate ameliorates hepatic steatosis by inhibiting lipogenesis and inflammation. | 2018 | Details |
A12187 | 30569636 | Obesity (Silver Spring) | Blackcurrant (Ribes nigrum) Prevents Obesity-Induced Nonalcoholic Steatohepatitis in Mice. | 2019 | Details |
A12207 | 30561388 | J Clin Invest | STING-mediated inflammation in Kupffer cells contributes to progression of nonalcoholic steatohepatitis. | 2018 | Details |
A12249 | 30547786 | BMC Med Genomics | Genomics of lipid-laden human hepatocyte cultures enables drug target screening for the treatment of non-alcoholic fatty liver disease. | 2018 | Details |
A12270 | 30540086 | Arq Gastroenterol | CORRELATION BETWEEN NONALCOHOLIC FATTY LIVER DISEASE FEATURES AND LEVELS OF ADIPOKINES AND INFLAMMATORY CYTOKINES AMONG MORBIDLY OBESE INDIVIDUALS. | 2019 | Details |
A12371 | 30483536 | JGH Open | Vitamin D supplementation in patients with nonalcoholic fatty liver disease: A randomized controlled trial. | 2017 | Details |
A12378 | 30477827 | Complement Ther Med | The effects of Zataria multiflora Boiss. (Shirazi thyme) on nonalcoholic fatty liver disease and insulin resistance: A randomized double-blind placebo-controlled clinical trial. | 2018 | Details |
A12400 | 30470953 | Dig Dis Sci | NAFLD Induction Delays Postoperative Liver Regeneration of ALPPS in Rats. | 2018 | Details |
A12421 | 30460863 | Pharm Biol | Mechanism of TangGanJian on nonalcoholic fatty liver disease with type 2 diabetes mellitus. | 2018 | Details |
A12502 | 30417996 | Pak J Biol Sci | Comparative Study of Orange and its Main Bioactive Constituents as Remedy for Non-alcoholic Fatty Liver in Rats. | 2018 | Details |
A12553 | 30394550 | Hepatology | A Regulatory Role of Apoptosis Antagonizing Transcription Factor in the Pathogenesis of Nonalcoholic Fatty Liver Disease and Hepatocellular Carcinoma. | 2019 | Details |
A12576 | 30382148 | Sci Rep | Augmented liver inflammation in a microsomal prostaglandin E synthase 1 (mPGES-1)-deficient diet-induced mouse NASH model. | 2018 | Details |
A12585 | 31949616 | Int J Clin Exp Pathol | N,N'-diacetylcystine ameliorates inflammation in experimental non-alcoholic steatohepatitis by regulating nuclear transcription factor kappa B activation. | 2018 | Details |
A12591 | 30372908 | Biomed Pharmacother | Hepatoprotective effect of bisbenzylisoquinoline alkaloid tiliamosine from Tiliacora racemosa in high-fat diet/diethylnitrosamine-induced non-alcoholic steatohepatitis. | 2018 | Details |
A12633 | 30358115 | Liver Transpl | Overproduction of Tenascin-C Driven by Lipid Accumulation in the Liver Aggravates Hepatic Ischemia/Reperfusion Injury in Steatotic Mice. | 2019 | Details |
A12640 | 30355361 | Lipids Health Dis | Sleeve gastrectomy attenuates high fat diet-induced non-alcoholic fatty liver disease. | 2018 | Details |
A12677 | 30333571 | Sci Rep | Imatinib reduces non-alcoholic fatty liver disease in obese mice by targeting inflammatory and lipogenic pathways in macrophages and liver. | 2018 | Details |
A12683 | 30328321 | Yonsei Med J | S100A4 Gene is Crucial for Methionine-Choline-Deficient Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice. | 2018 | Details |
A12812 | 30272851 | Asia Pac J Clin Nutr | Pro- and prebiotic effects on oxidative stress and inflammatory markers in non-alcoholic fatty liver disease. | 2019 | Details |
A12831 | 30263038 | Nutr Metab (Lond) | Green cardamom increases Sirtuin-1 and reduces inflammation in overweight or obese patients with non-alcoholic fatty liver disease: a double-blind randomized placebo-controlled clinical trial. | 2018 | Details |
A12869 | 30249323 | J Food Drug Anal | Effect of Phyllanthus emblica L. fruit on methionine and choline-deficiency diet-induced nonalcoholic steatohepatitis. | 2018 | Details |
A12877 | 30246507 | Helicobacter | Helicobacter pylori and non-alcoholic fatty liver disease: A new enigma? | 2018 | Details |
A12895 | 30236852 | Biomed Pharmacother | Protective effects of Kangxian ruangan capsule against nonalcoholic fatty liver disease fibrosis in rats induced by MCD diet. | 2018 | Details |
A12896 | 30235843 | Medicines (Basel) | Effects of Shugan-Jianpi Recipe on the Expression of the p38 MAPK/NF-κB Signaling Pathway in the Hepatocytes of NAFLD Rats. | 2018 | Details |
A12897 | 30235828 | Nutrients | Non-Alcoholic Fatty Liver Disease in Overweight Children: Role of Fructose Intake and Dietary Pattern. | 2018 | Details |
A12929 | 30221732 | Mol Med Rep | Inhibition of CCL19 benefits non‑alcoholic fatty liver disease by inhibiting TLR4/NF‑κB‑p65 signaling. | 2018 | Details |
A12936 | 30218679 | J Hepatol | MicroRNA-378 promotes hepatic inflammation and fibrosis via modulation of the NF-κB-TNFα pathway. | 2018 | Details |
A12947 | 30213555 | Gastroenterology | Expression of STING Is Increased in Liver Tissues From Patients With NAFLD and Promotes Macrophage-Mediated Hepatic Inflammation and Fibrosis in Mice. | 2018 | Details |
A12997 | 30189154 | Appl Physiol Nutr Metab | Camellia oleifera seed extract attenuated abdominal and hepatic fat accumulation in rats fed a high-fat diet. | 2018 | Details |
A13079 | 30145577 | Ann Hepatol | Salidroside and Curcumin Formula Prevents Liver Injury in Nonalcoholic Fatty Liver Disease in Rats. | 2018 | Details |
A13103 | 30137403 | J Clin Endocrinol Metab | Ghrelin Reduces TNF-α-Induced Human Hepatocyte Apoptosis, Autophagy, and Pyroptosis: Role in Obesity-Associated NAFLD. | 2019 | Details |
A13129 | 30125542 | Am J Pathol | Toll-Like Receptor-7 Signaling Promotes Nonalcoholic Steatohepatitis by Inhibiting Regulatory T Cells in Mice. | 2018 | Details |
A13150 | 30113661 | Nutr Rev | Prebiotic and probiotic treatment of nonalcoholic fatty liver disease: a systematic review and meta-analysis. | 2018 | Details |
A13156 | 30112044 | Exp Ther Med | Melatonin alleviates liver steatosis induced by prenatal dexamethasone exposure and postnatal high-fat diet. | 2018 | Details |
A13186 | 30096092 | Eur J Gastroenterol Hepatol | Rifaximin in nonalcoholic fatty liver disease: hit multiple targets with a single shot. | 2018 | Details |
A13193 | 30092591 | Cell Physiol Biochem | Bioactive Peptide Improves Diet-Induced Hepatic Fat Deposition and Hepatocyte Proinflammatory Response in SAMP8 Ageing Mice. | 2018 | Details |
A13261 | 30060508 | Int J Mol Sci | Harmful Effects and Potential Benefits of Anti-Tumor Necrosis Factor (TNF)-α on the Liver. | 2018 | Details |
A13322 | 30032465 | Sleep Breath | Non-alcoholic fatty liver disease is an independent risk factor for inflammation in obstructive sleep apnea syndrome in obese Asian Indians. | 2018 | Details |
A13363 | 30015859 | Int J Mol Med | Effect of celastrol on toll‑like receptor 4‑mediated inflammatory response in free fatty acid‑induced HepG2 cells. | 2018 | Details |
A13381 | 30009570 | Physiol Rep | Curcumin supplementation mitigates NASH development and progression in female Wistar rats. | 2018 | Details |
A13416 | 29989845 | Metab Syndr Relat Disord | Association Between Serum CK-18 Levels and the Degree of Liver Damage in Fructose-Induced Metabolic Syndrome. | 2018 | Details |
A13577 | 29898626 | Adipocyte | Glucoraphanin: a broccoli sprout extract that ameliorates obesity-induced inflammation and insulin resistance. | 2018 | Details |
A13607 | 29881816 | Hepatol Commun | Hepatic iron concentration correlates with insulin sensitivity in nonalcoholic fatty liver disease. | 2018 | Details |
A13638 | 29860102 | J Nutr Biochem | Disruption of tumor necrosis factor alpha receptor 1 signaling accelerates NAFLD progression in mice upon a high-fat diet. | 2018 | Details |
A13673 | 29845362 | Wien Klin Wochenschr | Increased intermediate monocyte fraction in peripheral blood is associated with nonalcoholic fatty liver disease. | 2018 | Details |
A13674 | 29845302 | Mol Med Rep | SIRT1 upregulation protects against liver injury induced by a HFD through inhibiting CD36 and the NF‑κB pathway in mouse kupffer cells. | 2018 | Details |
A13687 | 29805535 | Exp Ther Med | The therapeutic effects of bee venom on some metabolic and antioxidant parameters associated with HFD-induced non-alcoholic fatty liver in rats. | 2018 | Details |
A13698 | 29802679 | J Diabetes Investig | Soluble CD163 correlates with lipid metabolic adaptations in type 1 diabetes patients during ketoacidosis. | 2018 | Details |
A13797 | 29751074 | Food Chem Toxicol | Effects of high fructose intake on liver injury progression in high fat diet induced fatty liver disease in ovariectomized female mice. | 2018 | Details |
A13877 | 29713145 | Drug Des Devel Ther | Inhibition of ghrelin o-acyltransferase attenuated lipotoxicity by inducing autophagy via AMPK-mTOR pathway. | 2018 | Details |
A13884 | 29710519 | Biomed Pharmacother | Effects of shenling baizhu powder herbal formula on intestinal microbiota in high-fat diet-induced NAFLD rats. | 2018 | Details |
A13896 | 29704818 | Cytokine | Serum C1q/TNF-related protein 9 is not related to nonalcoholic fatty liver disease. | 2018 | Details |
A13898 | 29704259 | Hepatology | TRUSS Exacerbates NAFLD Development by Promoting IκBα Degradation in Mice. | 2018 | Details |
A13912 | 29697458 | Eur J Gastroenterol Hepatol | Effects of inflammatory bowel disease treatment on the risk of nonalcoholic fatty liver disease: a meta-analysis. | 2018 | Details |
A13938 | 29679615 | Metabolism | Novel protective role of kallistatin in obesity by limiting adipose tissue low grade inflammation and oxidative stress. | 2018 | Details |
A13972 | 29663549 | J Gastroenterol Hepatol | Ostreolysin induces browning of adipocytes and ameliorates hepatic steatosis. | 2018 | Details |
A13984 | 29657020 | Clin Res Hepatol Gastroenterol | Helicobacter pylori infection aggravates diet-induced nonalcoholic fatty liver in mice. | 2018 | Details |
A13994 | 29653359 | J Nutr Biochem | The role of the gut microbiota in the pathology and prevention of liver disease. | 2018 | Details |
A13996 | 29653100 | Chem Biol Interact | Vitamin D nanoemulsion enhances hepatoprotective effect of conventional vitamin D in rats fed with a high-fat diet. | 2018 | Details |
A13997 | 29652567 | J Am Coll Nutr | A Khorasan Wheat-Based Replacement Diet Improves Risk Profile of Patients With Nonalcoholic Fatty Liver Disease (NAFLD): A Randomized Clinical Trial. | 2018 | Details |
A14038 | 29622764 | Exp Mol Med | Glutathione disulfide sensitizes hepatocytes to TNFα-mediated cytotoxicity via IKK-β S-glutathionylation: a potential mechanism underlying non-alcoholic fatty liver disease. | 2018 | Details |
A14053 | 29608898 | Eur J Pharmacol | Canagliflozin protects against non-alcoholic steatohepatitis in type-2 diabetic rats through zinc alpha-2 glycoprotein up-regulation. | 2018 | Details |
A14102 | 29584449 | Crit Rev Food Sci Nutr | Efficacy of synbiotic supplementation in patients with nonalcoholic fatty liver disease: A systematic review and meta-analysis of clinical trials: Synbiotic supplementation and NAFLD. | 2018 | Details |
A14135 | 29569260 | Clin Exp Pharmacol Physiol | Down-regulation of microRNA-375 regulates adipokines and inhibits inflammatory cytokines by targeting AdipoR2 in non-alcoholic fatty liver disease. | 2018 | Details |
A14140 | 29567249 | J Food Drug Anal | Mulberry Leaf Extracts prevent obesity-induced NAFLD with regulating adipocytokines, inflammation and oxidative stress. | 2017 | Details |
A14144 | 29565153 | Nutr Hosp | Inflammatory cytokines and non-alcoholic fatty liver disease (NAFLD) in obese children and adolescents. | 2018 | Details |
A14162 | 29557414 | J Gastrointestin Liver Dis | A Multi-strain Probiotic Reduces the Fatty Liver Index, Cytokines and Aminotransferase levels in NAFLD Patients: Evidence from a Randomized Clinical Trial. | 2018 | Details |
A14172 | 29552625 | Cell Mol Gastroenterol Hepatol | Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2). | 2017 | Details |
A14183 | 29547047 | Endocr Pract | PEDIATRIC VISCERAL ADIPOSITY INDEX ADAPTATION CORRELATES WITH HOMA-IR, MATSUDA, AND TRANSAMINASES. | 2018 | Details |
A14216 | 29522534 | PLoS One | Niemann-Pick type C2 protein supplementation in experimental non-alcoholic fatty liver disease. | 2018 | Details |
A14221 | 29519316 | Phytomedicine | CGplus, a standardized herbal composition ameliorates non-alcoholic steatohepatitis in a tunicamycin-induced mouse model. | 2018 | Details |
A14330 | 29463133 | Arch Physiol Biochem | Effects of combined therapy with resveratrol, continuous and interval exercises on apoptosis, oxidative stress, and inflammatory biomarkers in the liver of old rats with non-alcoholic fatty liver disease. | 2018 | Details |
A14382 | 29434731 | Exp Ther Med | Correlation between PPAR-α methylation level in peripheral blood and inflammatory factors of NAFLD patients with DM. | 2017 | Details |
A14393 | 29429367 | Arch Physiol Biochem | Obestatin protects and reverses nonalcoholic fatty liver disease and its associated insulin resistance in rats via inhibition of food intake, enhancing hepatic adiponectin signaling, and blocking ghrelin acylation. | 2018 | Details |
A14395 | 29428667 | Biomed Pharmacother | Silybum marianum oil attenuates hepatic steatosis and oxidative stress in high fat diet-fed mice. | 2018 | Details |
A14407 | 29425212 | PLoS One | Insulin resistance in lean and overweight non-diabetic Caucasian adults: Study of its relationship with liver triglyceride content, waist circumference and BMI. | 2018 | Details |
A14413 | 29419350 | Ultrastruct Pathol | Swim exercise training ameliorates hepatocyte ultrastructural alterations in rats fed on a high fat and sugar diet. | 2018 | Details |
A14419 | 29414910 | Molecules | Hepatoprotective Effects of a Functional Formula of Three Chinese Medicinal Herbs: Experimental Evidence and Network Pharmacology-Based Identification of Mechanism of Action and Potential Bioactive Components. | 2018 | Details |
A14467 | 29399273 | World J Hepatol | Role of inflammatory response in liver diseases: Therapeutic strategies. | 2018 | Details |
A14473 | 29397594 | Zhonghua Nei Ke Za Zhi | [Efficacy of probiotics on the treatment of non-alcoholic fatty liver disease]. | 2018 | Details |
A14516 | 29373070 | J Med Food | Lipolysis-Stimulating Peptide from Soybean Protects Against High Fat Diet-Induced Apoptosis in Skeletal Muscles. | 2018 | Details |
A14520 | 29371773 | Indian J Clin Biochem | The Effects of Onion Consumption on Prevention of Nonalcoholic Fatty Liver Disease. | 2017 | Details |
A14526 | 29367619 | Cell Death Dis | Non-alcoholic fatty liver disease phenotypes in patients with inflammatory bowel disease. | 2018 | Details |
A14567 | 29350757 | J Food Sci | Hepatoprotective Effects of Sophoricoside against Fructose-Induced Liver Injury via Regulating Lipid Metabolism, Oxidation, and Inflammation in Mice. | 2018 | Details |
A14591 | 29335857 | Chin J Integr Med | Effect of Soothing Gan (Liver) and Invigorating Pi (Spleen) Recipes on TLR4-p38 MAPK Pathway in Kupffer Cells of Non-alcoholic Steatohepatitis Rats. | 2018 | Details |
A14609 | 29325294 | Zhonghua Gan Zang Bing Za Zhi | [Effects of Lactobacillus paracasei N1115 combined with fructooligosaccharides on non-alcoholic fatty liver disease induced by high-fat diet in mice]. | 2017 | Details |
A14644 | 29311399 | Ann Hepatol | Efficacy of Probiotics and Smectite in Rats with Non-Alcoholic Fatty Liver Disease. | 2018 | Details |
A14658 | 29305845 | Clin Chim Acta | Serum CTRP3 level is inversely associated with nonalcoholic fatty liver disease: A 3-y longitudinal study. | 2018 | Details |
A14691 | 29287776 | Biochim Biophys Acta Mol Basis Dis | Activin-A causes Hepatic stellate cell activation via the induction of TNFα and TGFβ in Kupffer cells. | 2017 | Details |
A14768 | 29247950 | Biomed Pharmacother | Baicalin attenuates diet induced nonalcoholic steatohepatitis by inhibiting inflammation and oxidative stress via suppressing JNK signaling pathways. | 2017 | Details |