Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A01090 | 34871812 | Clin Gastroenterol Hepatol | Intensive Lifestyle Management Improves Steatosis and Fibrosis in Pediatric Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01091 | 34871361 | Arch Pathol Lab Med | Pathologic Diagnosis of Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01092 | 34871234 | Medicine (Baltimore) | Clinical predictive score for detecting nonalcoholic fatty liver disease with significant fibrosis in patients with metabolic syndrome. | 2021 | Details |
| A01096 | 34870139 | Metabol Open | Protective effects of cerium oxide nanoparticles in non-alcoholic fatty liver disease (NAFLD) and carbon tetrachloride-induced liver damage in rats: Study on intestine and liver. | 2021 | Details |
| A01098 | 34869957 | JACC Basic Transl Sci | Relationship of Nonalcoholic Fatty Liver Disease and Heart Failure With Preserved Ejection Fraction. | 2021 | Details |
| A01100 | 34869532 | Front Nutr | Clinical Relevance of Vitamins and Carotenoids With Liver Steatosis and Fibrosis Detected by Transient Elastography in Adults. | 2021 | Details |
| A01104 | 34869352 | Front Cell Dev Biol | Cholesterol Metabolism: A Double-Edged Sword in Hepatocellular Carcinoma. | 2021 | Details |
| A01111 | 34866849 | J Clin Exp Hepatol | Tobacco, Cigarettes, and the Liver: The Smoking Gun. | 2021 | Details |
| A01114 | 34866842 | J Clin Exp Hepatol | Adipocytokines as Risk Factors for Development of Nonalcoholic Fatty Liver Disease in Children. | 2021 | Details |
| A01128 | 34861841 | BMC Gastroenterol | FIB-4, APRI, and AST/ALT ratio compared to FibroScan for the assessment of hepatic fibrosis in patients with non-alcoholic fatty liver disease in Bandar Abbas, Iran. | 2021 | Details |
| A01129 | 34861339 | Prev Med | Physical activity and diet quality in relation to non-alcoholic fatty liver disease: A cross-sectional study in a representative sample of U.S. adults using NHANES 2017-2018. | 2021 | Details |
| A01138 | 34858322 | Front Endocrinol (Lausanne) | The Impact of Dysmetabolic Sarcopenia Among Insulin Sensitive Tissues: A Narrative Review. | 2021 | Details |
| A01140 | 34857244 | Clin Nutr ESPEN | High prevalence of hepatic steatosis and hepatic fibrosis in patients with type 2 diabetes mellitus. | 2021 | Details |
| A01147 | 34855339 | FP Essent | Liver Disease: Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A01148 | 34854929 | Eur Radiol | Comparative diagnostic performance of ultrasound shear wave elastography and magnetic resonance elastography for classifying fibrosis stage in adults with biopsy-proven nonalcoholic fatty liver disease. | 2021 | Details |
| A01149 | 34854066 | Hormones (Athens) | Nonalcoholic fatty liver disease: lifestyle and quality of life. | 2021 | Details |
| A01168 | 34847156 | PLoS One | Screening for undiagnosed non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH): A population-based risk factor assessment using vibration controlled transient elastography (VCTE). | 2021 | Details |
| A01169 | 34845832 | Liver Int | Binge drinking induces an acute burst of markers of hepatic fibrogenesis (PRO-C3). | 2021 | Details |
| A01172 | 34841632 | Hepatol Res | Comparison of diagnostic performance between FIB-4 and NFS in metabolic-associated fatty liver disease era. | 2021 | Details |
| A01193 | 34831479 | Cells | Accumulation of Genetic and Epigenetic Alterations in the Background Liver and Emergence of Hepatocellular Carcinoma in Patients with Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A01196 | 34830997 | Cancers (Basel) | Hepatocellular Carcinoma in Non-Alcoholic Fatty Liver Disease: From Epidemiology to Diagnostic Approach. | 2021 | Details |
| A01199 | 34830313 | Int J Mol Sci | Aryl Hydrocarbon Receptor (AhR) Activation by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) Dose-Dependently Shifts the Gut Microbiome Consistent with the Progression of Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A01204 | 34829876 | Biomedicines | Estimating Drug Efficacy with a Diet-Induced NASH Model in Chimeric Mice with Humanized Livers. | 2021 | Details |
| A01207 | 34829753 | Biomedicines | Genetics, Immunity and Nutrition Boost the Switching from NASH to HCC. | 2021 | Details |
| A01210 | 34829394 | Diagnostics (Basel) | A Step Closer to the "Fourth 90": A Practical Narrative Review of Diagnosis and Management of Nutritional Issues of People Living with HIV. | 2021 | Details |
| A01212 | 34828420 | Genes (Basel) | Circulatory Endothelin 1-Regulating RNAs Panel: Promising Biomarkers for Non-Invasive NAFLD/NASH Diagnosis and Stratification: Clinical and Molecular Pilot Study. | 2021 | Details |
| A01218 | 34825156 | JHEP Rep | Bile acids contribute to the development of non-alcoholic steatohepatitis in mice. | 2021 | Details |
| A01219 | 34825068 | Biochem Biophys Rep | Metformin treatment reverses high fat diet- induced non-alcoholic fatty liver diseases and dyslipidemia by stimulating multiple antioxidant and anti-inflammatory pathways. | 2021 | Details |
| A01227 | 34822395 | Metabolites | Aqueous Metabolite Trends for the Progression of Nonalcoholic Fatty Liver Disease in Female Bariatric Surgery Patients by Targeted 1H-NMR Metabolomics. | 2021 | Details |
| A01230 | 34821093 | Zhongguo Ying Yong Sheng Li Xue Za Zhi | [Effects of curcumol on liver function and fibrosis in rats of nonalcoholic fatty liver disease and its mechanism]. | 2021 | Details |
| A01231 | 34821035 | Liver Int | Inflammatory activity affects the accuracy of liver stiffness measurement by transient elastography but not by two-dimensional shear wave elastography in non-alcoholic fatty liver disease. | 2021 | Details |
| A01235 | 34819013 | Endocr Metab Immune Disord Drug Targets | Emerging Role of Interleukins for the Assessment and Treatment of Liver Diseases. | 2022 | Details |
| A01236 | 34818372 | PLoS One | Subclinical steatohepatitis and advanced liver fibrosis in health examinees with nonalcoholic fatty liver disease (NAFLD) in 10 South Korean cities: A retrospective cross-sectional study. | 2021 | Details |
| A01242 | 34816355 | Obes Surg | Routine Versus Selective Liver Biopsy During Bariatric Surgery: Postoperative Outcomes and Preoperative Predictors of NASH. | 2021 | Details |
| A01244 | 34815553 | Nat Rev Endocrinol | Non-invasive methods for imaging hepatic steatosis and their clinical importance in NAFLD. | 2021 | Details |
| A01245 | 34815444 | Sci Rep | A 3D primary human cell-based in vitro model of non-alcoholic steatohepatitis for efficacy testing of clinical drug candidates. | 2021 | Details |
| A01255 | 34813621 | PLoS One | Assessment of non-alcoholic fatty liver disease (NAFLD) severity with novel serum-based markers: A pilot study. | 2021 | Details |
| A01258 | 34813249 | Arch Argent Pediatr | [Obesity-fatty liver: the role of the pediatrician]. | 2021 | Details |
| A01259 | 34811857 | Aging Cell | Cisd2 slows down liver aging and attenuates age-related metabolic dysfunction in male mice. | 2021 | Details |
| A01260 | 34811578 | Handb Exp Pharmacol | NAFLD and NASH: The Metabolically Diseased Liver. | 2021 | Details |
| A01261 | 34810377 | Saudi J Gastroenterol | Association of metabolic traits with occurrence of nonalcoholic fatty liver disease-related hepatocellular carcinoma: A systematic review and meta-analysis of longitudinal cohort studies. | 2022 | Details |
| A01263 | 34809436 | Annu Rev Med | Fatty Liver Disease: Diagnosis and Stratification. | 2021 | Details |
| A01264 | 34809412 | Endocrinol Metab (Seoul) | The Leg Fat to Total Fat Ratio Is Associated with Lower Risks of Non-Alcoholic Fatty Liver Disease and Less Severe Hepatic Fibrosis: Results from Nationwide Surveys (KNHANES 2008-2011). | 2021 | Details |
| A01269 | 34808388 | Bioorg Med Chem Lett | Design, synthesis and activity evaluation of prodrug form JBP485 and Vitamin E for alleviation of NASH. | 2021 | Details |
| A01274 | 34805582 | Transl Gastroenterol Hepatol | Narrative review of current and emerging pharmacological therapies for nonalcoholic steatohepatitis. | 2021 | Details |
| A01292 | 34799510 | Curr Opin Infect Dis | Frailty in people living with HIV: an update. | 2022 | Details |
| A01295 | 34798835 | BMC Gastroenterol | PNPLA3 genotype and fibrosis-4 index predict cardiovascular diseases of Japanese patients with histopathologically-confirmed NAFLD. | 2021 | Details |
| A01297 | 34798176 | J Hepatol | MRI-based (MAST) score accurately identifies patients with NASH and significant fibrosis. | 2021 | Details |
| A01301 | 34796096 | Pediatr Gastroenterol Hepatol Nutr | Distinctive Features of Hepatic Steatosis in Children: Is It Primary or Secondary to Inborn Errors of Metabolism? | 2021 | Details |
| A01303 | 34795650 | Front Microbiol | Dextran Sulfate Sodium Salt-Induced Colitis Aggravates Gut Microbiota Dysbiosis and Liver Injury in Mice With Non-alcoholic Steatohepatitis. | 2021 | Details |
| A01307 | 34794237 | Biomed Pharmacother | Anti-inflammatory and anti-fibrotic effects of modafinil in nonalcoholic liver disease. | 2021 | Details |
| A01309 | 34794182 | Semin Liver Dis | The Neglected Role of Bile Duct Epithelial Cells in NASH. | 2021 | Details |
| A01311 | 34793868 | J Hepatol | Non-invasive evaluation of response to obeticholic acid in patients with NASH: Results from the REGENERATE study. | 2021 | Details |
| A01312 | 34793866 | J Hepatol | A new perspective on NAFLD: Focusing on lipid droplets. | 2021 | Details |
| A01313 | 34791524 | Int J Colorectal Dis | Disease activity in inflammatory bowel disease patients is associated with increased liver fat content and liver fibrosis during follow-up. | 2021 | Details |
| A01315 | 34790034 | Int J Med Sci | Radiomics based on fluoro-deoxyglucose positron emission tomography predicts liver fibrosis in biopsy-proven MAFLD: a pilot study. | 2021 | Details |
| A01320 | 34788749 | Oncology | Dynamics of Circulating miR-122 Predict Liver Cancer and Mortality in Japanese Patients with Histopathologically Confirmed NAFLD and Severe Fibrosis Stage. | 2021 | Details |
| A01321 | 34788612 | Cell Rep | TM4SF5-dependent crosstalk between hepatocytes and macrophages to reprogram the inflammatory environment. | 2021 | Details |
| A01325 | 34786828 | Kaohsiung J Med Sci | Serum Wisteria floribunda agglutinin-positive Mac-2-binding protein expression predicts disease severity in nonalcoholic steatohepatitis patients. | 2021 | Details |
| A01326 | 34786549 | JHEP Rep | Prospective comparison of transient elastography, MRI and serum scores for grading steatosis and detecting non-alcoholic steatohepatitis in bariatric surgery candidates. | 2021 | Details |
| A01330 | 34786215 | IEEE J Transl Eng Health Med | Ultrasound Sample Entropy Imaging: A New Approach for Evaluating Hepatic Steatosis and Fibrosis. | 2021 | Details |
| A01336 | 34785385 | Clin Res Hepatol Gastroenterol | Trans-anethole attenuates diet-induced nonalcoholic steatohepatitis through suppressing TGF-β-mediated fibrosis. | 2021 | Details |
| A01337 | 34784620 | Exp Clin Endocrinol Diabetes | Shear Wave Elastography Reveals a High Prevalence of NAFLD-related Fibrosis Even in Type 1 Diabetes. | 2021 | Details |
| A01340 | 34783191 | Hepatol Commun | Predicting Liver-Related Outcomes in People With Nonalcoholic Fatty Liver Disease: The Prognostic Value of Noninvasive Fibrosis Tests. | 2021 | Details |
| A01341 | 34783091 | J Hum Nutr Diet | The Dietary Inflammatory Index and hepatic health in the US adult population. | 2021 | Details |
| A01353 | 34777740 | Ther Adv Chronic Dis | The association between NAFLD and risk of chronic kidney disease: a cross-sectional study. | 2021 | Details |
| A01355 | 34777261 | Front Endocrinol (Lausanne) | Endotoxins and Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A01358 | 34775841 | Exp Biol Med (Maywood) | Bioinformatics analysis of an animal model of diet-induced nonalcoholic fatty liver disease with rapid progression. | 2021 | Details |
| A01360 | 34774753 | Mol Ther | An RNAi therapeutic targeting hepatic DGAT2 in a genetically obese mouse model of nonalcoholic steatohepatitis. | 2021 | Details |
| A01368 | 34773257 | Hepatology | A GLP-1/GLP-2 receptor dual agonist to treat NASH: Targeting the gut-liver axis and microbiome. | 2021 | Details |
| A01371 | 34772312 | J Int Med Res | Use of GP73 in the diagnosis of non-alcoholic steatohepatitis and the staging of hepatic fibrosis. | 2021 | Details |
| A01375 | 34769333 | Int J Mol Sci | Clinical and Molecular Biomarkers for Diagnosis and Staging of NAFLD. | 2021 | Details |
| A01376 | 34769332 | Int J Mol Sci | Association between Equol Production Status and Nonalcoholic Steatohepatitis. | 2021 | Details |
| A01383 | 34765514 | J Tradit Complement Med | Genistein and exercise treatment reduced NASH related HDAC3, IL-13 and MMP-12 expressions in ovariectomized rats fed with high fat high fructose diet. | 2021 | Details |
| A01385 | 34765085 | Oxid Med Cell Longev | Target Sestrin2 to Rescue the Damaged Organ: Mechanistic Insight into Its Function. | 2021 | Details |
| A01389 | 34763561 | J Int Med Res | Does the FT3-to-FT4 ratio easily predict the progression of NAFLD and NASH cirrhosis? | 2021 | Details |
| A01391 | 34762911 | J Biol Chem | Hepatocyte-specific perturbation of NAD+ biosynthetic pathways in mice induces reversible nonalcoholic steatohepatitis-like phenotypes. | 2021 | Details |
| A01392 | 34762779 | Arch Endocrinol Metab | Acoustic radiation force impulse elastography and liver fibrosis risk scores in severe obesity. | 2021 | Details |
| A01395 | 34762106 | JAMA | Association of Bariatric Surgery With Major Adverse Liver and Cardiovascular Outcomes in Patients With Biopsy-Proven Nonalcoholic Steatohepatitis. | 2021 | Details |
| A01396 | 34761883 | Minerva Med | Inflammatory-nutritional scores in the diagnosis of NASH and liver fibrosis. | 2021 | Details |
| A01399 | 34760965 | Hepatobiliary Surg Nutr | Accuracy of non-invasive liver stiffness measurement and steatosis quantification in patients with severe and morbid obesity. | 2021 | Details |
| A01408 | 34757352 | Mol Omics | Identification of disease-associated microRNA in a diet-induced model of nonalcoholic steatohepatitis. | 2021 | Details |
| A01409 | 34757199 | Clin Gastroenterol Hepatol | Disease Progression Modeling for Economic Evaluation in Nonalcoholic Fatty Liver Disease-A Systematic Review. | 2021 | Details |
| A01416 | 34755918 | Environ Toxicol | Polystyrene nanoplastics potentiate the development of hepatic fibrosis in high fat diet fed mice. | 2021 | Details |
| A01420 | 34755002 | J Endocr Soc | Underrecognition of Nonalcoholic Fatty Liver Disease in Poorly Controlled Diabetes: A Call to Action in Diabetes Care. | 2021 | Details |
| A01422 | 34754150 | World J Gastroenterol | Acetyl-CoA carboxylase inhibitors in non-alcoholic steatohepatitis: Is there a benefit? | 2021 | Details |
| A01425 | 34753223 | Liver Transpl | Noninvasive Risk Stratification for Nonalcoholic Fatty Liver Disease Among Living Liver Donor Candidates: A Proposed Algorithm. | 2021 | Details |
| A01428 | 34752711 | Annu Rev Pathol | Role of the Inflammasome in Liver Disease. | 2021 | Details |
| A01429 | 34750345 | Sci Rep | Albino mice with the point mutation at the tyrosinase locus show high cholesterol diet-induced NASH susceptibility. | 2021 | Details |
| A01433 | 34749354 | Hum Hered | Association of PNPLA3 I148M with Liver Disease Biomarkers in Latinos. | 2021 | Details |
| A01437 | 34746195 | Front Med (Lausanne) | Liver Fibrosis and MAFLD: From Molecular Aspects to Novel Pharmacological Strategies. | 2021 | Details |
| A01438 | 34746184 | Front Med (Lausanne) | Gene Signatures Detect Damaged Liver Sinusoidal Endothelial Cells in Chronic Liver Diseases. | 2021 | Details |
| A01439 | 34746177 | Front Med (Lausanne) | Genetic Polymorphisms and Clinical Features in Diabetic Patients With Fatty Liver: Results From a Single-Center Experience in Southern Italy. | 2021 | Details |
| A01442 | 34745017 | Front Endocrinol (Lausanne) | The Role of RECK in Hepatobiliary Neoplasia Reveals Its Therapeutic Potential in NASH. | 2021 | Details |
| A01443 | 34743980 | Eur J Pharmacol | Preventive and therapeutic role of betaine in liver disease: A review on molecular mechanisms. | 2021 | Details |
| A01444 | 34743657 | Adipocyte | Association of cell death mechanisms and fibrosis in visceral white adipose tissue with pathological alterations in the liver of morbidly obese patients with NAFLD. | 2021 | Details |
| A01447 | 34742814 | Gastroenterol Hepatol | Body composition and phase angle by bioimpedance in patients with MAFLD. | 2021 | Details |
| A01456 | 34740705 | J Hepatol | EDP-305 in patients with NASH: A phase II double-blind placebo-controlled dose-ranging study. | 2021 | Details |
| A01457 | 34740672 | Toxicology | MCLR-elicited hepatic fibrosis and carcinogenic gene expression changes persist in rats with diet-induced nonalcoholic steatohepatitis through a 4-week recovery period. | 2021 | Details |
| A01471 | 34736312 | Clin Mol Hepatol | U-shaped relationship between urea level and hepatic decompensation in chronic liver diseases. | 2021 | Details |