Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
stats1
stats2
stats3
stats4
Search for:
Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A18193 | 27296438 | BMC Gastroenterol | Development of a novel mouse model of hepatocellular carcinoma with nonalcoholic steatohepatitis using a high-fat, choline-deficient diet and intraperitoneal injection of diethylnitrosamine. | 2016 | Details |
| A18196 | 27291420 | Sci Rep | Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system. | 2016 | Details |
| A18204 | 27288055 | J Endocrinol | Metformin increases hepatic leptin receptor and decreases steatosis in mice. | 2016 | Details |
| A18205 | 27287838 | Orv Hetil | [Non-alcoholic fatty liver disease and hepatocellular carcinoma - 2016]. | 2016 | Details |
| A18216 | 27279075 | Sci Rep | Toll-like receptor 7 affects the pathogenesis of non-alcoholic fatty liver disease. | 2016 | Details |
| A18222 | 27276701 | Liver Int | Nonalcoholic fatty liver disease: cause or consequence of type 2 diabetes? | 2016 | Details |
| A18230 | 27270872 | Phytother Res | Treatment of Non-alcoholic Fatty Liver Disease with Curcumin: A Randomized Placebo-controlled Trial. | 2016 | Details |
| A18253 | 27262842 | Acta Biochim Pol | Hepatokines and non-alcoholic fatty liver disease. | 2016 | Details |
| A18257 | 27261776 | Mol Med | Activation of proteinase 3 contributes to Non-alcoholic Fatty Liver Disease (NAFLD) and insulin resistance. | 2016 | Details |
| A18258 | 27261415 | J Hepatol | A diet-induced animal model of non-alcoholic fatty liver disease and hepatocellular cancer. | 2016 | Details |
| A18262 | 27257426 | Hepat Mon | Leptin Receptor Gene Polymorphisms and the Risk of Non-Alcoholic Fatty Liver Disease and Coronary Atherosclerosis in the Chinese Han Population. | 2016 | Details |
| A18266 | 27255583 | J Hepatol | Effect of exercise on the development of new fatty liver and the resolution of existing fatty liver. | 2016 | Details |
| A18267 | 27254774 | Liver Int | ADAMTS5 deficiency protects against non-alcoholic steatohepatitis in obesity. | 2016 | Details |
| A18270 | 27252817 | Middle East J Dig Dis | An Accessible and Pragmatic Experimental Model of Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18276 | 27248435 | Curr Protoc Mouse Biol | Development of a Representative Mouse Model with Nonalcoholic Steatohepatitis. | 2016 | Details |
| A18279 | 27246737 | Biochem Biophys Res Commun | Supplementing dietary sugar promotes endoplasmic reticulum stress-independent insulin resistance and fatty liver in goose. | 2016 | Details |
| A18280 | 27246655 | Sci Rep | Association of Non-alcoholic Fatty Liver Disease with Metabolic Syndrome Independently of Central Obesity and Insulin Resistance. | 2016 | Details |
| A18281 | 27245430 | J Hepatol | Hepatocyte vitamin D receptor regulates lipid metabolism and mediates experimental diet-induced steatosis. | 2016 | Details |
| A18285 | 29879345 | Yao Xue Xue Bao | [Investigating the effects of compound WS090152 on non-alcoholic fatty liver in mice]. | 2016 | Details |
| A18288 | 27239734 | Lab Invest | C/EBP homologous protein modulates liraglutide-mediated attenuation of non-alcoholic steatohepatitis. | 2016 | Details |
| A18292 | 27237577 | Metabolism | Non-alcoholic fatty liver disease and dyslipidemia: An update. | 2016 | Details |
| A18298 | 27231906 | Int J Mol Sci | NAFLD and NASH in HCV Infection: Prevalence and Significance in Hepatic and Extrahepatic Manifestations. | 2016 | Details |
| A18303 | 27226903 | Sultan Qaboos Univ Med J | Mechanisms of Diabetes-Induced Liver Damage: The role of oxidative stress and inflammation. | 2016 | Details |
| A18307 | 27222533 | Gut | Stress-activated miR-21/miR-21* in hepatocytes promotes lipid and glucose metabolic disorders associated with high-fat diet consumption. | 2016 | Details |
| A18309 | 27221093 | Diabetologia | A novel hepatokine, HFREP1, plays a crucial role in the development of insulin resistance and type 2 diabetes. | 2016 | Details |
| A18317 | 27216550 | J Cell Physiol | Association Between Aerobic Exercise and Rosiglitazone Avoided the NAFLD and Liver Inflammation Exacerbated in PPAR-α Knockout Mice. | 2016 | Details |
| A18322 | 27213061 | Case Rep Endocrinol | Panhypopituitarism due to Absence of the Pituitary Stalk: A Rare Aetiology of Liver Cirrhosis. | 2016 | Details |
| A18324 | 27211699 | Clin Biochem | Serum metabonomics of NAFLD plus T2DM based on liquid chromatography-mass spectrometry. | 2016 | Details |
| A18327 | 27207512 | Diabetes | Variants in Genes Controlling Oxidative Metabolism Contribute to Lower Hepatic ATP Independent of Liver Fat Content in Type 1 Diabetes. | 2016 | Details |
| A18328 | 27207510 | Diabetes | Lipodystrophy Due to Adipose Tissue-Specific Insulin Receptor Knockout Results in Progressive NAFLD. | 2016 | Details |
| A18332 | 27200103 | Evid Based Complement Alternat Med | A Fomitopsis pinicola Jeseng Formulation Has an Antiobesity Effect and Protects against Hepatic Steatosis in Mice with High-Fat Diet-Induced Obesity. | 2016 | Details |
| A18336 | 27197843 | Br J Nutr | Preventive effects of citrulline on Western diet-induced non-alcoholic fatty liver disease in rats. | 2016 | Details |
| A18341 | 27196572 | Gut | Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid metabolism. | 2016 | Details |
| A18345 | 27190693 | World J Gastrointest Pathophysiol | Insulin resistance in development and progression of nonalcoholic fatty liver disease. | 2016 | Details |
| A18347 | 27189281 | Yonsei Med J | The Relationship between Type 2 Diabetes Mellitus and Non-Alcoholic Fatty Liver Disease Measured by Controlled Attenuation Parameter. | 2016 | Details |
| A18348 | 27188904 | Nutr Res | Alternate-day fasting protects the livers of mice against high-fat diet-induced inflammation associated with the suppression of Toll-like receptor 4/nuclear factor κB signaling. | 2016 | Details |
| A18350 | 27187452 | Nutrients | Gut Microbiota and Metabolic Health: The Potential Beneficial Effects of a Medium Chain Triglyceride Diet in Obese Individuals. | 2016 | Details |
| A18351 | 27187365 | Int J Mol Sci | Non-Alcoholic Fatty Liver Disease and Extra-Hepatic Cancers. | 2016 | Details |
| A18352 | 27185609 | Lancet Diabetes Endocrinol | Phenotypes of prediabetes and stratification of cardiometabolic risk. | 2016 | Details |
| A18355 | 27185080 | Am J Gastroenterol | Metabolically Healthy Obesity and the Development of Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18356 | 27184920 | Sci Rep | Preventing High Fat Diet-induced Obesity and Improving Insulin Sensitivity through Neuregulin 4 Gene Transfer. | 2016 | Details |
| A18362 | 27181889 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | [Roles of MicroRNA-21 in the Pathogenesis of Insulin Resistance and Diabetic Mellitus-induced Non-alcoholic Fatty Liver Disease]. | 2016 | Details |
| A18364 | 27181051 | Sci Rep | Ces3/TGH Deficiency Attenuates Steatohepatitis. | 2016 | Details |
| A18370 | 27178444 | Liver Int | Advanced non-alcoholic fatty liver disease and adipose tissue fibrosis in patients with Alström syndrome. | 2016 | Details |
| A18375 | 27174364 | Br J Pharmacol | Hepatic NAD(+) deficiency as a therapeutic target for non-alcoholic fatty liver disease in ageing. | 2016 | Details |
| A18378 | 27173514 | Environ Int | Association between exposures to brominated trihalomethanes, hepatic injury and type II diabetes mellitus. | 2016 | Details |
| A18379 | 27173510 | Am J Physiol Gastrointest Liver Physiol | Compounds of the sphingomyelin-ceramide-glycosphingolipid pathways as secondary messenger molecules: new targets for novel therapies for fatty liver disease and insulin resistance. | 2016 | Details |
| A18382 | 27172901 | Oncotarget | IL-33 treatment attenuated diet-induced hepatic steatosis but aggravated hepatic fibrosis. | 2016 | Details |
| A18386 | 27170389 | Dig Dis | Non-Alcoholic Steatohepatitis: From Pathophysiology to Novel Therapies. | 2016 | Details |
| A18387 | 27169860 | BMC Res Notes | Subclinical inflammation in relation to insulin resistance in prediabetic subjects with nonalcoholic fatty liver disease. | 2016 | Details |
| A18390 | 27166773 | Clinics (Sao Paulo) | FT3/FT4 ratio predicts non-alcoholic fatty liver disease independent of metabolic parameters in patients with euthyroidism and hypothyroidism. | 2016 | Details |
| A18391 | 27166182 | Oncotarget | Reduced miR-200b and miR-200c expression contributes to abnormal hepatic lipid accumulation by stimulating JUN expression and activating the transcription of srebp1. | 2016 | Details |
| A18393 | 27164963 | Chin J Integr Med | Protective Effects of Chaihu Shugan San () on Nonalcoholic Fatty Liver Disease in Rats with Insulin Resistance. | 2016 | Details |
| A18395 | 27164079 | Int J Mol Sci | Vascular Damage in Patients with Nonalcoholic Fatty Liver Disease: Possible Role of Iron and Ferritin. | 2016 | Details |
| A18398 | 27160697 | Dig Liver Dis | Non-alcoholic fatty liver disease fibrosis score and preclinical vascular damage in morbidly obese patients. | 2016 | Details |
| A18408 | 27153234 | Chemosphere | Metabolic and immune impairments induced by the endocrine disruptors benzo[a]pyrene and triclosan in Xenopus tropicalis. | 2016 | Details |
| A18412 | 27151177 | J Hepatol | Sitagliptin vs. placebo for non-alcoholic fatty liver disease: A randomized controlled trial. | 2016 | Details |
| A18413 | 27150853 | Intern Med | Significance of Hepatic Insulin Clearance in Patients with Chronic Hepatitis C and Non-alcoholic Fatty Liver Disease. | 2016 | Details |
| A18417 | 27148532 | Front Cell Dev Biol | Roles of FGFs As Paracrine or Endocrine Signals in Liver Development, Health, and Disease. | 2016 | Details |
| A18420 | 27146015 | Annu Rev Nutr | Citrus Flavonoids as Regulators of Lipoprotein Metabolism and Atherosclerosis. | 2016 | Details |
| A18421 | 27146014 | Annu Rev Nutr | Hormonal and Metabolite Regulation of Hepatic Glucokinase. | 2016 | Details |
| A18422 | 27146012 | Annu Rev Nutr | Alterations of Mitochondrial Function and Insulin Sensitivity in Human Obesity and Diabetes Mellitus. | 2016 | Details |
| A18423 | 27145114 | Mol Nutr Food Res | Biochanin A improves hepatic steatosis and insulin resistance by regulating the hepatic lipid and glucose metabolic pathways in diet-induced obese mice. | 2016 | Details |
| A18424 | 27145007 | Endocrinology | Maternal Hyperleptinemia Improves Offspring Insulin Sensitivity in Mice. | 2016 | Details |
| A18426 | 27143968 | Int J Endocrinol | Histopathologic Evaluation of Nonalcoholic Fatty Liver Disease in Hypothyroidism-Induced Rats. | 2016 | Details |
| A18429 | 27142870 | Diabetes Metab | Risk of type 2 diabetes in patients with non-alcoholic fatty liver disease: Causal association or epiphenomenon? | 2016 | Details |
| A18430 | 27142744 | J Nutr Biochem | Liquid fructose in pregnancy exacerbates fructose-induced dyslipidemia in adult female offspring. | 2016 | Details |
| A18431 | 27142736 | J Nutr Biochem | Fucoidan alleviates high-fat diet-induced dyslipidemia and atherosclerosis in ApoE(shl) mice deficient in apolipoprotein E expression. | 2016 | Details |
| A18437 | 27135827 | PLoS One | A Series of microRNA in the Chromosome 14q32.2 Maternally Imprinted Region Related to Progression of Non-Alcoholic Fatty Liver Disease in a Mouse Model. | 2016 | Details |
| A18440 | 27134062 | Nutr Metab Cardiovasc Dis | Insulin resistance, postprandial GLP-1 and adaptive immunity are the main predictors of NAFLD in a homogeneous population at high cardiovascular risk. | 2016 | Details |
| A18448 | 27128911 | Int J Mol Sci | Definitions of Normal Liver Fat and the Association of Insulin Sensitivity with Acquired and Genetic NAFLD-A Systematic Review. | 2016 | Details |
| A18453 | 27124954 | Genome Med | Antibiotic perturbation of the murine gut microbiome enhances the adiposity, insulin resistance, and liver disease associated with high-fat diet. | 2016 | Details |
| A18454 | 27124606 | J Cardiovasc Pharmacol | Curcumin Lowers Serum Lipids and Uric Acid in Subjects With Nonalcoholic Fatty Liver Disease: A Randomized Controlled Trial. | 2016 | Details |
| A18457 | 27122660 | World J Gastroenterol | Nonalcoholic fatty liver disease as a multi-systemic disease. | 2016 | Details |
| A18458 | 27121255 | Int J Obes (Lond) | Intervention with a caspase-1 inhibitor reduces obesity-associated hyperinsulinemia, non-alcoholic steatohepatitis and hepatic fibrosis in LDLR-/-.Leiden mice. | 2016 | Details |
| A18459 | 27121253 | Int J Obes (Lond) | Reduced circulating levels of sTWEAK are associated with NAFLD and may affect hepatocyte triglyceride accumulation. | 2016 | Details |
| A18464 | 27110380 | BMJ Open Gastroenterol | Statins, antidiabetic medications and liver histology in patients with diabetes with non-alcoholic fatty liver disease. | 2016 | Details |
| A18466 | 27110262 | Hepat Mon | Ginger Supplementation in Nonalcoholic Fatty Liver Disease: A Randomized, Double-Blind, Placebo-Controlled Pilot Study. | 2016 | Details |
| A18469 | 27109162 | Am J Chin Med | Rheum palmatum L. Attenuates High Fat Diet-Induced Hepatosteatosis by Activating AMP-Activated Protein Kinase. | 2016 | Details |
| A18470 | 27107966 | Best Pract Res Clin Obstet Gynaecol | Hepatic manifestations of women with polycystic ovary syndrome. | 2016 | Details |
| A18472 | 27106721 | Diabetologia | Higher body fat percentage is associated with enhanced temperature perception in NAFLD: results from the randomised Wessex Evaluation of fatty Liver and Cardiovascular markers in NAFLD with OMacor thErapy trial (WELCOME) trial. | 2016 | Details |
| A18476 | 27104558 | Nutrients | Insulin Protects Hepatic Lipotoxicity by Regulating ER Stress through the PI3K/Akt/p53 Involved Pathway Independently of Autophagy Inhibition. | 2016 | Details |
| A18484 | 27101131 | Diabetologia | Treatment of patients with type 2 diabetes and non-alcoholic fatty liver disease: current approaches and future directions. | 2016 | Details |
| A18494 | 27091184 | Diabetologia | Diagnosis of non-alcoholic fatty liver disease (NAFLD). | 2016 | Details |
| A18495 | 27091156 | Cell Mol Life Sci | Hypoxia-regulated mechanisms in the pathogenesis of obesity and non-alcoholic fatty liver disease. | 2016 | Details |
| A18497 | 27091074 | Sci Rep | Phosphorylated IGFBP-1 as a non-invasive predictor of liver fat in NAFLD. | 2016 | Details |
| A18500 | 27089408 | J Pediatr Endocrinol Metab | Low 25-hydroxyvitamin D level is not an independent risk factor for hepatosteatosis in obese children. | 2016 | Details |
| A18514 | 27077854 | Int J Mol Sci | Role of Serum Uric Acid and Ferritin in the Development and Progression of NAFLD. | 2016 | Details |
| A18518 | 27076501 | Hum Reprod | Non-alcoholic fatty liver disease is associated with insulin resistance and lipid accumulation product in women with polycystic ovary syndrome. | 2016 | Details |
| A18523 | 27073470 | Exp Ther Med | Low simvastatin concentrations reduce oleic acid-induced steatosis in HepG2 cells: An in vitro model of non-alcoholic fatty liver disease. | 2016 | Details |
| A18524 | 27072576 | Oncotarget | Utilization of animal models to investigate nonalcoholic steatohepatitis-associated hepatocellular carcinoma. | 2016 | Details |
| A18528 | 27068982 | Biochem Soc Trans | Blood triacylglycerols: a lipidomic window on diet and disease. | 2016 | Details |
| A18538 | 27063275 | Clin Liver Dis | Emerging Therapies for Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18539 | 27063274 | Clin Liver Dis | Current Pharmacologic Therapy for Nonalcoholic Fatty Liver Disease. | 2016 | Details |
| A18546 | 27063267 | Clin Liver Dis | Nonalcoholic Fatty Liver Disease: Lipids and Insulin Resistance. | 2016 | Details |
| A18547 | 27063266 | Clin Liver Dis | The Metabolic Syndrome and Its Influence on Nonalcoholic Steatohepatitis. | 2015 | Details |
| A18554 | 28702244 | Clin Diabetes Endocrinol | Treatment of Nonalcoholic Fatty Liver Disease (NAFLD) in patients with Type 2 Diabetes Mellitus. | 2016 | Details |
| A18560 | 27057272 | Oxid Med Cell Longev | Aging Increases Susceptibility to High Fat Diet-Induced Metabolic Syndrome in C57BL/6 Mice: Improvement in Glycemic and Lipid Profile after Antioxidant Therapy. | 2016 | Details |
| A18577 | 27051590 | BBA Clin | Diabetic and dyslipidaemic morbidly obese exhibit more liver alterations compared with healthy morbidly obese. | 2016 | Details |
| A18578 | 27049488 | Ann Hepatol | Nonalcoholic steatohepatitis in morbid obese patients: coffee consumption vs. disease severity. | 2017 | Details |