Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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40433 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A04270 | 33681091 | Can J Gastroenterol Hepatol | Metabolic Alteration in Hepatocellular Carcinoma: Mechanism of Lipid Accumulation in Well-Differentiated Hepatocellular Carcinoma. | 2021 | Details |
| A04271 | 33681089 | Can J Gastroenterol Hepatol | NAFLD, Insulin Resistance, and Diabetes Mellitus Type 2. | 2021 | Details |
| A04272 | 33680496 | Obes Sci Pract | α-Tocopherol suppresses hepatic steatosis by increasing CPT-1 expression in a mouse model of diet-induced nonalcoholic fatty liver disease. | 2020 | Details |
| A04273 | 33680428 | Hepat Oncol | Characterizing the mechanism behind the progression of NAFLD to hepatocellular carcinoma. | 2020 | Details |
| A04274 | 33680375 | Caspian J Intern Med | Recurrence of fatty liver disease following liver transplantation for NAFLD-related cirrhosis: Current status and challenges. | 2020 | Details |
| A04275 | 33680282 | Oxid Med Cell Longev | Hepatoprotection of Lycii Fructus Polysaccharide against Oxidative Stress in Hepatocytes and Larval Zebrafish. | 2021 | Details |
| A04276 | 33679874 | Front Genet | Associations Among Methylene Tetrahydrofolate Reductase rs1801133 C677T Gene Variant, Food Groups, and Non-alcoholic Fatty Liver Disease Risk in the Chinese Population. | 2021 | Details |
| A04277 | 33679803 | Front Immunol | Revisiting the Role of Natural Killer Cells in Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A04278 | 33679403 | Front Pharmacol | Ginsenosides Improve Nonalcoholic Fatty Liver Disease via Integrated Regulation of Gut Microbiota, Inflammation and Energy Homeostasis. | 2021 | Details |
| A04279 | 33679386 | Front Pharmacol | Insulin Fused to Apolipoprotein A-I Reduces Body Weight and Steatosis in DB/DB Mice. | 2021 | Details |
| A04280 | 33679051 | J Clin Exp Hepatol | Successful Outcome of Bariatric Surgery in Living Donor Liver Transplant Recipients With Multidisciplinary Approach: A Preliminary Experience. | 2020 | Details |
| A04281 | 33679048 | J Clin Exp Hepatol | The Association Between Nonalcoholic Fatty Liver Disease and Risk of Cardiovascular Disease, Stroke, and Extrahepatic Cancers. | 2020 | Details |
| A04282 | 33679045 | J Clin Exp Hepatol | Comparison of Elastography Point Quantification with Transient Elastography in Patients with Chronic Viral Hepatitis and Nonalcoholic Fatty Liver Disease: A Pilot Study. | 2020 | Details |
| A04284 | 33678110 | Gut Microbes | Akkermansia muciniphila and environmental enrichment reverse cognitive impairment associated with high-fat high-cholesterol consumption in rats. | 2022 | Details |
| A04285 | 33678036 | Hum Exp Toxicol | Early intervention with probiotics and metformin alleviates liver injury in NAFLD rats via targeting gut microbiota dysbiosis and p-AKT/mTOR/LC-3II pathways. | 2021 | Details |
| A04286 | 33677935 | Endocrinol Metab (Seoul) | Development of a Non-Invasive Liver Fibrosis Score Based on Transient Elastography for Risk Stratification in Patients with Type 2 Diabetes. | 2021 | Details |
| A04288 | 33676874 | Surg Obes Relat Dis | The metabolic and liver-related outcomes of bariatric surgery in adult patients with insulin-treated type 2 diabetes and nonalcoholic fatty liver disease at high risk of liver fibrosis. | 2020 | Details |
| A04289 | 33675775 | Biochem Pharmacol | Activation of FXR modulates SOCS3/Jak2/STAT3 signaling axis in a NASH-dependent hepatocellular carcinoma animal model. | 2021 | Details |
| A04290 | 33675573 | J Dig Dis | Liver and serum adiponectin levels in non-alcoholic fatty liver disease. | 2021 | Details |
| A04291 | 33675475 | Int Urol Nephrol | Prevalence of non-alcoholic fatty liver disease among patients with non-diabetic chronic kidney disease detected by transient elastography. | 2021 | Details |
| A04293 | 33674694 | Sci Rep | DSS-induced colitis is associated with adipose tissue dysfunction and disrupted hepatic lipid metabolism leading to hepatosteatosis and dyslipidemia in mice. | 2021 | Details |
| A04294 | 33673227 | Nutrients | Temporal Development of Dyslipidemia and Nonalcoholic Fatty Liver Disease (NAFLD) in Syrian Hamsters Fed a High-Fat, High-Fructose, High-Cholesterol Diet. | 2021 | Details |
| A04295 | 33673113 | Biomedicines | Natural Progression of Non-Alcoholic Steatohepatitis to Hepatocellular Carcinoma. | 2021 | Details |
| A04296 | 33673073 | Int J Mol Sci | Effect of Chronic Western Diets on Non-Alcoholic Fatty Liver of Male Mice Modifying the PPAR-γ Pathway via miR-27b-5p Regulation. | 2021 | Details |
| A04297 | 33672887 | Toxins (Basel) | Fungi-Bacteria Correlation in Alcoholic Hepatitis Patients. | 2021 | Details |
| A04298 | 33672864 | Life (Basel) | FIB-4 First in the Diagnostic Algorithm of Metabolic-Dysfunction-Associated Fatty Liver Disease in the Era of the Global Metabodemic. | 2021 | Details |
| A04299 | 33672827 | Cancers (Basel) | Performance of Ultrasound Techniques and the Potential of Artificial Intelligence in the Evaluation of Hepatocellular Carcinoma and Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A04300 | 33672787 | Int J Mol Sci | Absence of Adiponutrin (PNPLA3) and Monoacylglycerol Lipase Synergistically Increases Weight Gain and Aggravates Steatohepatitis in Mice. | 2021 | Details |
| A04301 | 33672073 | Nutrients | Energy Expenditure Improved Risk Factors Associated with Renal Function Loss in NAFLD and MetS Patients. | 2021 | Details |
| A04302 | 33671926 | Int J Mol Sci | Sarcopenic Obesity in Liver Cirrhosis: Possible Mechanism and Clinical Impact. | 2021 | Details |
| A04303 | 33671880 | Biomedicines | Immunomodulatory Role of Urolithin A on Metabolic Diseases. | 2021 | Details |
| A04304 | 33671850 | Nutrients | Omega-3 Polyunsaturated Fatty Acids Prevent Nonalcoholic Steatohepatitis (NASH) and Stimulate Adipogenesis. | 2021 | Details |
| A04305 | 33671715 | Molecules | Antioxidant and Antisteatotic Activities of a New Fucoidan Extracted from Ferula hermonis Roots Harvested on Lebanese Mountains. | 2021 | Details |
| A04306 | 33671567 | Cells | Identification of Accessible Hepatic Gene Signatures for Interindividual Variations in Nutrigenomic Response to Dietary Supplementation of Omega-3 Fatty Acids. | 2021 | Details |
| A04307 | 33671547 | Int J Mol Sci | Association of Adipose Tissue and Adipokines with Development of Obesity-Induced Liver Cancer. | 2021 | Details |
| A04308 | 33671486 | Molecules | Influence of Genistein on Hepatic Lipid Metabolism in an In Vitro Model of Hepatic Steatosis. | 2021 | Details |
| A04309 | 33671262 | Nutrients | A Novel Nutraceuticals Mixture Improves Liver Steatosis by Preventing Oxidative Stress and Mitochondrial Dysfunction in a NAFLD Model. | 2021 | Details |
| A04310 | 33670839 | Antioxidants (Basel) | Changes in Glutathione Content in Liver Diseases: An Update. | 2021 | Details |
| A04311 | 33670347 | Nutrients | Epigallocatechin-3-Gallate Dampens Non-Alcoholic Fatty Liver by Modulating Liver Function, Lipid Profile and Macrophage Polarization. | 2021 | Details |
| A04312 | 33669443 | J Clin Med | Roles of Ceramides in Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A04313 | 33669288 | Int J Environ Res Public Health | Relationships between Socioeconomic Status, Handgrip Strength, and Non-Alcoholic Fatty Liver Disease in Middle-Aged Adults. | 2021 | Details |
| A04314 | 33668222 | Int J Environ Res Public Health | Tobacco Smoke and CYP1A2 Activity in a US Population with Normal Liver Enzyme Levels. | 2021 | Details |
| A04315 | 33668153 | Cancers (Basel) | MicroRNA-21 Plays Multiple Oncometabolic Roles in the Process of NAFLD-Related Hepatocellular Carcinoma via PI3K/AKT, TGF-β, and STAT3 Signaling. | 2021 | Details |
| A04316 | 33668077 | J Gastroenterol Hepatol | Systematic review: Accuracy of the enhanced liver fibrosis test for diagnosing advanced liver fibrosis and cirrhosis. | 2021 | Details |
| A04317 | 33667726 | Mol Metab | Pharmacologic inhibition of ketohexokinase prevents fructose-induced metabolic dysfunction. | 2021 | Details |
| A04318 | 33667513 | Life Sci | Exercise improves lipid droplet metabolism disorder through activation of AMPK-mediated lipophagy in NAFLD. | 2021 | Details |
| A04320 | 33665859 | J Food Biochem | Protective effects of Dendrobium candidum Wall ex Lindl. on high-fat diet-induced liver damage in mice. | 2021 | Details |
| A04321 | 33665755 | Obes Surg | Decision Tree for the Performance of Intraoperative Liver Biopsy During Bariatric Surgery. | 2021 | Details |
| A04322 | 33665589 | JHEP Rep | From congestive hepatopathy to hepatocellular carcinoma, how can we improve patient management? | 2021 | Details |
| A04323 | 33665585 | JHEP Rep | Cell of origin in biliary tract cancers and clinical implications. | 2021 | Details |
| A04324 | 33665291 | Pract Lab Med | Low levels of spexin and adiponectin may predict insulin resistance in patients with non-alcoholic fatty liver. | 2021 | Details |
| A04325 | 33665203 | Front Nutr | The Impact of Macronutrient Intake on Non-alcoholic Fatty Liver Disease (NAFLD): Too Much Fat, Too Much Carbohydrate, or Just Too Many Calories? | 2021 | Details |
| A04326 | 33665176 | Front Pediatr | Liver Enzymes Correlate With Metabolic Syndrome, Inflammation, and Endothelial Dysfunction in Prepubertal Children With Obesity. | 2021 | Details |
| A04327 | 33664710 | Front Endocrinol (Lausanne) | Comparison of the Efficacy of Glucagon-Like Peptide-1 Receptor Agonists in Patients With Metabolic Associated Fatty Liver Disease: Updated Systematic Review and Meta-Analysis. | 2021 | Details |
| A04328 | 33664397 | Sci Rep | Hepatic lymphocytes involved in the pathogenesis of pediatric and adult non-alcoholic fatty liver disease. | 2021 | Details |
| A04329 | 33664363 | Sci Rep | The incidence trends of liver cirrhosis caused by nonalcoholic steatohepatitis via the GBD study 2017. | 2021 | Details |
| A04330 | 33664289 | Sci Rep | Clodronate, an inhibitor of the vesicular nucleotide transporter, ameliorates steatohepatitis and acute liver injury. | 2021 | Details |
| A04331 | 33664225 | Cell Death Dis | Hepatic HuR protects against the pathogenesis of non-alcoholic fatty liver disease by targeting PTEN. | 2021 | Details |
| A04332 | 33664007 | Arab J Gastroenterol | Short-term orlistat therapy improves fatty infiltration indices and liver fibrosis scores in patients with non-alcoholic fatty liver disease and metabolic syndrome. | 2021 | Details |
| A04333 | 33662773 | Clin Res Hepatol Gastroenterol | Low levels of Lysosomal Acid Lipase (LAL) activity increases necroinflammation in adult patients with biopsy-proven metabolic associated fatty liver disease. | 2021 | Details |
| A04334 | 33660958 | Croat Med J | Non-alcoholic fatty liver disease - a procoagulant condition? | 2021 | Details |
| A04336 | 33659890 | JHEP Rep | Case-finding strategies in non-alcoholic fatty liver disease. | 2020 | Details |
| A04337 | 33659827 | Vavilovskii Zhurnal Genet Selektsii | Apoptosis in the liver of male db/db mice during the development of obesity and type 2 diabetes. | 2020 | Details |
| A04338 | 33658534 | Sci Rep | Beneficial effects of elafibranor on NASH in E3L.CETP mice and differences between mice and men. | 2021 | Details |
| A04339 | 33658485 | Cell Death Dis | WW domain-binding protein 2 overexpression prevents diet-induced liver steatosis and insulin resistance through AMPKβ1. | 2021 | Details |
| A04340 | 33658438 | Endocr J | Association between serum 25-hydroxy vitamin D level and metabolic associated fatty liver disease (MAFLD)-a population-based study. | 2021 | Details |
| A04341 | 33658436 | Mol Cells | Increased Hepatic Lipogenesis Elevates Liver Cholesterol Content. | 2021 | Details |
| A04342 | 33657584 | J Hypertens | Blood pressure, glycemic status and advanced liver fibrosis assessed by transient elastography in the general United States population. | 2021 | Details |
| A04343 | 33657443 | Contemp Clin Trials | The FALCON program: Two phase 2b randomized, double-blind, placebo-controlled studies to assess the efficacy and safety of pegbelfermin in the treatment of patients with nonalcoholic steatohepatitis and bridging fibrosis or compensated cirrhosis. | 2021 | Details |
| A04344 | 33657386 | Cell Metab | Proton pump inhibitor use status does not modify the microbiome signature for cirrhosis. | 2021 | Details |
| A04345 | 33656663 | Hepatol Int | Gut-liver axis modulation of Panax notoginseng saponins in nonalcoholic fatty liver disease. | 2021 | Details |
| A04346 | 33655500 | Br J Pharmacol | Activation of thyroid hormone receptor-β improved disease activity and metabolism independent of body weight in a mouse model of non-alcoholic steatohepatitis and fibrosis. | 2021 | Details |
| A04348 | 33653293 | BMC Gastroenterol | Non-alcoholic fatty liver disease and cognitive function in middle-aged adults: the CARDIA study. | 2021 | Details |
| A04349 | 33652942 | Int J Mol Sci | Treatments for NAFLD: State of Art. | 2021 | Details |
| A04350 | 33652658 | Nutrients | Is the Mediterranean Diet the Best Approach to NAFLD Treatment Today? | 2021 | Details |
| A04352 | 33652261 | Biomed Pharmacother | Akebia saponin D ameliorates metabolic syndrome (MetS) via remodeling gut microbiota and attenuating intestinal barrier injury. | 2021 | Details |
| A04353 | 33651661 | Gut Microbes | Links between gut microbiome composition and fatty liver disease in a large population sample. | 2022 | Details |
| A04354 | 33650781 | Physiol Rep | Serum fetuin-A and Ser312 phosphorylated fetuin-A responses and markers of insulin sensitivity after a single bout of moderate intensity exercise. | 2021 | Details |
| A04356 | 33648923 | Eur Cytokine Netw | Absence of increased liver-related inflammatory markers in type 1 diabetes with metabolic syndrome: a nested case-control study from Brazil. | 2020 | Details |
| A04357 | 33648885 | Obes Res Clin Pract | Comparison between non-invasive methods and liver histology to stratify liver fibrosis in obese patients submitted to bariatric surgery. | 2021 | Details |
| A04358 | 33648723 | J Natl Med Assoc | Trends in the Incidence of Hepatocellular Carcinoma in Washington DC: A Single Institutional Cohort Study (1959-2013). | 2021 | Details |
| A04359 | 33648515 | Cardiovasc Diabetol | Effect of empagliflozin on ectopic fat stores and myocardial energetics in type 2 diabetes: the EMPACEF study. | 2021 | Details |
| A04360 | 33647942 | Endocrinology | Hepatic Igf1-Deficiency Protects Against Atherosclerosis in Female Mice. | 2021 | Details |
| A04361 | 33647884 | Aging (Albany NY) | Exercise in mice ameliorates high-fat diet-induced nonalcoholic fatty liver disease by lowering HMGCS2. | 2021 | Details |
| A04362 | 33647823 | Int Immunopharmacol | The SGLT2 inhibitor empagliflozin negatively regulates IL-17/IL-23 axis-mediated inflammatory responses in T2DM with NAFLD via the AMPK/mTOR/autophagy pathway. | 2021 | Details |
| A04363 | 33647632 | Clin Imaging | Digital image analysis of ultrasound images using machine learning to diagnose pediatric nonalcoholic fatty liver disease. | 2021 | Details |
| A04364 | 33647584 | Cytokine | Lipid-injured hepatocytes release sOPN to improve macrophage migration via CD44 engagement and pFak-NFκB signaling. | 2021 | Details |
| A04365 | 33647502 | Ann Hepatol | The presence of diabetes impacts liver fibrosis and steatosis by transient elastography in a primary care population. | 2021 | Details |
| A04366 | 33647280 | Gastroenterology | Squalene Epoxidase Induces Nonalcoholic Steatohepatitis Via Binding to Carbonic Anhydrase III and is a Therapeutic Target. | 2021 | Details |
| A04367 | 33647205 | Chem Res Toxicol | LXRα/β Antagonism Protects against Lipid Accumulation in the Liver but Increases Plasma Cholesterol in Rhesus Macaques. | 2021 | Details |
| A04368 | 33644233 | Biomed Res Int | Plateletcrit and Mean Platelet Volume in the Evaluation of Alcoholic Liver Cirrhosis and Nonalcoholic Fatty Liver Disease Patients. | 2021 | Details |
| A04369 | 33644215 | World J Clin Cases | Nonalcoholic fatty liver disease as a risk factor for cytomegalovirus hepatitis in an immunocompetent patient: A case report. | 2021 | Details |
| A04370 | 33643422 | Evid Based Complement Alternat Med | Gegen Qinlian Decoction Ameliorates Nonalcoholic Fatty Liver Disease in Rats via Oxidative Stress, Inflammation, and the NLRP3 Signal Axis. | 2021 | Details |
| A04371 | 33643221 | Front Endocrinol (Lausanne) | Sodium-Glucose Co-Transporter 2 Inhibitors for Non-Alcoholic Fatty Liver Disease in Asian Patients With Type 2 Diabetes: A Meta-Analysis. | 2021 | Details |
| A04372 | 33643038 | Front Pharmacol | Gallic Acid Ameliorated Impaired Lipid Homeostasis in a Mouse Model of High-Fat Diet-and Streptozotocin-Induced NAFLD and Diabetes through Improvement of β-oxidation and Ketogenesis. | 2021 | Details |
| A04373 | 33642832 | World J Gastroenterol | Quantitative multiparametric magnetic resonance imaging can aid non-alcoholic steatohepatitis diagnosis in a Japanese cohort. | 2021 | Details |
| A04374 | 33642826 | World J Gastroenterol | Prevalence of advanced liver fibrosis and steatosis in type-2 diabetics with normal transaminases: A prospective cohort study. | 2021 | Details |
| A04375 | 33642741 | J Indian Soc Periodontol | Association between nonalcoholic fatty liver disease and inflammatory periodontal disease: A case‑control study. | 2020 | Details |
| A04376 | 33642551 | Biol Pharm Bull | Deletion of TRPC3 or TRPC6 Fails to Attenuate the Formation of Inflammation and Fibrosis in Non-alcoholic Steatohepatitis. | 2021 | Details |
| A04377 | 33642355 | Saudi J Gastroenterol | The effect of hepatic steatosis on COVID-19 severity: Chest computed tomography findings. | 2021 | Details |