Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A49483 | 35740254 | Biomedicines | Effects of Thyroid Hormones on Lipid Metabolism Pathologies in Non-Alcoholic Fatty Liver Disease. | 2022 | Details |
| A49487 | 35739990 | Antioxidants (Basel) | Vanadium(IV)-Chlorodipicolinate Protects against Hepatic Steatosis by Ameliorating Lipid Peroxidation, Endoplasmic Reticulum Stress, and Inflammation. | 2022 | Details |
| A49503 | 35733920 | J Immunol Res | Exploring and Verifying the Mechanism and Targets of Shenqi Pill in the Treatment of Nonalcoholic Steatohepatitis via Network Pharmacology and Experiments. | 2022 | Details |
| A49506 | 35733070 | Mol Biol Rep | Metformin protects against ethanol-induced liver triglyceride accumulation by the LKB1/AMPK/ACC pathway. | 2022 | Details |
| A49507 | 35732081 | Eur J Med Chem | Synthesis and biological evaluation of tyrosine derivatives as peripheral 5HT2A receptor antagonists for nonalcoholic fatty liver disease. | 2022 | Details |
| A49524 | 35726797 | Food Funct | Astragalus mongholicus polysaccharides ameliorate hepatic lipid accumulation and inflammation as well as modulate gut microbiota in NAFLD rats. | 2022 | Details |
| A49532 | 35723304 | Curr Issues Mol Biol | Tremella fuciformis Crude Polysaccharides Attenuates Steatosis and Suppresses Inflammation in Diet-Induced NAFLD Mice. | 2022 | Details |
| A49542 | 35721123 | Front Pharmacol | Identifying Candidate Flavonoids for Non-Alcoholic Fatty Liver Disease by Network-Based Strategy. | 2022 | Details |
| A49543 | 35720958 | 3 Biotech | Amelioration of high-fat diet (HFD) + CCl4 induced NASH/NAFLD in CF-1 mice by activation of SIRT-1 using cinnamoyl sulfonamide hydroxamate derivatives: in-silico molecular modelling and in-vivo prediction. | 2022 | Details |
| A49544 | 35720181 | Oxid Med Cell Longev | Chrysin Attenuates Fructose-Induced Nonalcoholic Fatty Liver in Rats via Antioxidant and Anti-Inflammatory Effects: The Role of Angiotensin-Converting Enzyme 2/Angiotensin (1-7)/Mas Receptor Axis. | 2022 | Details |
| A49546 | 35720113 | Front Mol Biosci | Ferroptosis in Chronic Liver Diseases: Opportunities and Challenges. | 2022 | Details |
| A49550 | 35718058 | Am J Pathol | Dysregulation of Lipid and Glucose Homeostasis in Hepatocyte-Specific SLC25A34 Knockout Mice. | 2022 | Details |
| A49557 | 35714571 | Biochem Biophys Res Commun | LncNONMMUG027912 alleviates lipid accumulation through AMPKα/mTOR/SREBP1C axis in nonalcoholic fatty liver. | 2022 | Details |
| A49577 | 35708630 | J Med Food | Nil-Surin Rice Bran Hydrolysates Improve Lipid Metabolism and Hepatic Steatosis by Regulating Secretion of Adipokines and Expression of Lipid-Metabolism Genes. | 2022 | Details |
| A49597 | 35696209 | J Food Drug Anal | Apigenin ameliorates hepatic lipid accumulation by activating the autophagy-mitochondria pathway. | 2021 | Details |
| A49615 | 35691075 | Phytomedicine | Saikosaponin D attenuates metabolic associated fatty liver disease by coordinately tuning PPARα and INSIG/SREBP1c pathway. | 2022 | Details |
| A49628 | 35685876 | Front Nutr | Sucralose, a Non-nutritive Artificial Sweetener Exacerbates High Fat Diet-Induced Hepatic Steatosis Through Taste Receptor Type 1 Member 3. | 2022 | Details |
| A49632 | 35684158 | Nutrients | 11β-HSD1 Inhibitor Alleviates Non-Alcoholic Fatty Liver Disease by Activating the AMPK/SIRT1 Signaling Pathway. | 2022 | Details |
| A49635 | 35684022 | Nutrients | Effect of Dietary and Lifestyle Interventions on the Amelioration of NAFLD in Patients with Metabolic Syndrome: The FLIPAN Study. | 2022 | Details |
| A49638 | 35683987 | Nutrients | The Role of Phytosterols in Nonalcoholic Fatty Liver Disease. | 2022 | Details |
| A49641 | 35682942 | Int J Mol Sci | Betaine Alleviates High-Fat Diet-Induced Disruptionof Hepatic Lipid and Iron Homeostasis in Mice. | 2022 | Details |
| A49643 | 35682720 | Int J Mol Sci | Maternal Pyrroloquinoline Quinone Supplementation Improves Offspring Liver Bioactive Lipid Profiles throughout the Lifespan and Protects against the Development of Adult NAFLD. | 2022 | Details |
| A49649 | 35679904 | J Lipid Res | Inhibition of MAP4K4 Signaling Initiaties Metabolic Reprogramming to Protect Hepatocytes from Lipotoxic Damage. | 2022 | Details |
| A49665 | 35677177 | Comput Math Methods Med | Effect of Probiotics Therapy on Nonalcoholic Fatty Liver Disease. | 2022 | Details |
| A49673 | 35673914 | Nan Fang Yi Ke Da Xue Xue Bao | [TSPAN8 is involved in lipid metabolism in non-alcoholic fatty liver disease in mice]. | 2022 | Details |
| A49679 | 35672633 | Environ Sci Pollut Res Int | Microarray analysis of mRNA expression profiles in liver of ob/ob mice with real-time atmospheric PM2.5 exposure. | 2022 | Details |
| A49722 | 35657688 | Diabetes | The Liver-Alpha Cell Axis in Health and in Disease. | 2022 | Details |
| A49743 | 35651973 | Front Endocrinol (Lausanne) | Contribution of Liver and Pancreatic Islet Crosstalk to β-Cell Function/Dysfunction in the Presence of Fatty Liver. | 2022 | Details |
| A49746 | 35651514 | Front Nutr | Polydatin, A Glycoside of Resveratrol, Is Better Than Resveratrol in Alleviating Non-alcoholic Fatty Liver Disease in Mice Fed a High-Fructose Diet. | 2022 | Details |
| A49758 | 35646261 | World J Hepatol | Total cholesterol to high-density lipoprotein ratio and nonalcoholic fatty liver disease in a population with chronic hepatitis B. | 2022 | Details |
| A49759 | 35646144 | Evid Based Complement Alternat Med | Inhibitory Effects of Mongolian Medicine Yihe-Tang on Continuous Darkness Induced Liver Steatosis in Zebrafish. | 2022 | Details |
| A49785 | 35637971 | Int J Biol Sci | Quantitative proteomics of HFD-induced fatty liver uncovers novel transcription factors of lipid metabolism. | 2022 | Details |
| A49786 | 35637957 | Int J Biol Sci | The GR-gp78 Pathway is involved in Hepatic Lipid Accumulation Induced by Overexpression of 11β-HSD1. | 2022 | Details |
| A49791 | 35636255 | Biochem Biophys Res Commun | The effects of brewers' spent grain on high-fat diet-induced fatty liver. | 2022 | Details |
| A49792 | 35636169 | Phytomedicine | Pharmacological effects of polydatin in the treatment of metabolic diseases: A review. | 2022 | Details |
| A49800 | 35634340 | Front Immunol | The Potential Role of Gut Microbial-Derived Exosomes in Metabolic-Associated Fatty Liver Disease: Implications for Treatment. | 2022 | Details |
| A49802 | 35633911 | World J Gastroenterol | Peroxisome proliferator-activated receptor-alpha activation and dipeptidyl peptidase-4 inhibition target dysbiosis to treat fatty liver in obese mice. | 2022 | Details |
| A49807 | 35631240 | Nutrients | Effect of Dietary Supplementation with Eufortyn® Colesterolo Plus on Serum Lipids, Endothelial Reactivity, Indexes of Non-Alcoholic Fatty Liver Disease and Systemic Inflammation in Healthy Subjects with Polygenic Hypercholesterolemia: The ANEMONE Study. | 2022 | Details |
| A49829 | 35625757 | Biomedicines | Comparative Transcriptome Analysis Reveals That Exendin-4 Improves Steatosis in HepG2 Cells by Modulating Signaling Pathways Related to Lipid Metabolism. | 2022 | Details |
| A49833 | 35625599 | Biomolecules | Role of TFEB in Autophagy and the Pathogenesis of Liver Diseases. | 2022 | Details |
| A49836 | 35624839 | Antioxidants (Basel) | Modulation of Oxidative Stress-Induced Senescence during Non-Alcoholic Fatty Liver Disease. | 2022 | Details |
| A49838 | 35624769 | Antioxidants (Basel) | Ramulus Mori (Sangzhi) Alkaloids Alleviate High-Fat Diet-Induced Obesity and Nonalcoholic Fatty Liver Disease in Mice. | 2022 | Details |
| A49840 | 35624756 | Antioxidants (Basel) | Hydroxytyrosol Promotes the Mitochondrial Function through Activating Mitophagy. | 2022 | Details |
| A49847 | 35622622 | Toxics | Bisphenol A Coupled with a High-Fat Diet Promotes Hepatosteatosis through Reactive-Oxygen-Species-Induced CD36 Overexpression. | 2022 | Details |
| A49848 | 35621963 | Mar Drugs | Monkfish Peptides Mitigate High Fat Diet-Induced Hepatic Steatosis in Mice. | 2022 | Details |
| A49851 | 35620160 | Chronic Dis Transl Med | Hepatic hormone FGF21 and its analogues in clinical trials. | 2022 | Details |
| A49858 | 35616339 | J Cell Physiol | The Clock-NAD+ -Sirtuin connection in nonalcoholic fatty liver disease. | 2022 | Details |
| A49861 | 35616069 | Food Funct | Walnut green husk ethanol extract improves gut microbiota and their metabolites associated with NLRP3 in non-alcoholic steatohepatitis. | 2022 | Details |
| A49875 | 35612781 | Mol Biol Rep | Advances of microRNAs in regulating mitochondrial function: new potential application in NAFLD treatment. | 2022 | Details |
| A49897 | 35605052 | J Cell Biochem | Targeting the lysosome: Mechanisms and treatments for nonalcoholic fatty liver disease. | 2022 | Details |
| A49925 | 35592528 | Oxid Med Cell Longev | Ficus hirta Vahl. Ameliorates Nonalcoholic Fatty Liver Disease through Regulating Lipid Metabolism and Gut Microbiota. | 2022 | Details |
| A49929 | 35590366 | J Nanobiotechnology | A novel nanobody-heavy chain antibody against Angiopoietin-like protein 3 reduces plasma lipids and relieves nonalcoholic fatty liver disease. | 2022 | Details |
| A49936 | 35589016 | Toxicol Lett | Upregulation of hepatic CD36 via glucocorticoid receptor activation contributes to dexamethasone-induced liver lipid metabolism disorder in mice. | 2022 | Details |
| A49944 | 35586049 | Front Pharmacol | Artemether Ameliorates Non-Alcoholic Steatohepatitis by Repressing Lipogenesis, Inflammation, and Fibrosis in Mice. | 2022 | Details |
| A49945 | 35586044 | Front Pharmacol | Protective Effects of Tiaoganquzhi Decoction in Treating inflammatory Injury of Nonalcoholic Fatty liver Disease by Promoting CGI-58 and Inhibiting Expression of NLRP3 Inflammasome. | 2022 | Details |
| A49947 | 35585376 | Mol Biol Rep | Krüppel-like factors in glycolipid metabolic diseases. | 2022 | Details |
| A49955 | 35583480 | J Agric Food Chem | Spermidine Ameliorates Nonalcoholic Steatohepatitis through Thyroid Hormone-Responsive Protein Signaling and the Gut Microbiota-Mediated Metabolism of Bile Acids. | 2022 | Details |
| A49973 | 35577161 | J Ethnopharmacol | Network pharmacology analysis on mechanism of Jian Pi Qing Gan Yin decoction ameliorating high fat diet-induced non-alcoholic fatty liver disease and validated in vivo. | 2022 | Details |
| A49991 | 35569768 | Gene | White tea alleviates non-alcoholic fatty liver disease by regulating energy expenditure and lipid metabolism. | 2022 | Details |
| A49993 | 35568374 | Biochim Biophys Acta Mol Cell Biol Lipids | Implications of microbe-mediated crosstalk in the gut: Impact on metabolic diseases. | 2022 | Details |
| A49994 | 35568228 | Life Sci | Protective effects of maslinic acid on high fat diet-induced liver injury in mice. | 2022 | Details |
| A50007 | 35565666 | Nutrients | Myristica fragrans Extract Regulates Gut Microbes and Metabolites to Attenuate Hepatic Inflammation and Lipid Metabolism Disorders via the AhR-FAS and NF-κB Signaling Pathways in Mice with Non-Alcoholic Fatty Liver Disease. | 2022 | Details |
| A50018 | 35563076 | Int J Mol Sci | Acacetin Protects against Non-Alcoholic Fatty Liver Disease by Regulating Lipid Accumulation and Inflammation in Mice. | 2022 | Details |
| A50039 | 35551031 | Food Chem | A designed self-microemulsion delivery system for dihydromyricetin and its dietary intervention effect on high-fat-diet fed mice. | 2022 | Details |
| A50043 | 35548355 | Front Pharmacol | Diosgenin Ameliorates Non-alcoholic Fatty Liver Disease by Modulating the Gut Microbiota and Related Lipid/Amino Acid Metabolism in High Fat Diet-Fed Rats. | 2022 | Details |
| A50056 | 35543143 | Food Funct | Co-interventions with Clostridium butyricum and soluble dietary fiber targeting the gut microbiota improve MAFLD via the Acly/Nrf2/NF-κB signaling pathway. | 2022 | Details |
| A50068 | 35537139 | Food Funct | Corn peptides improved obesity-induced non-alcoholic fatty liver disease through relieving lipid metabolism, insulin resistance and oxidative stress. | 2022 | Details |
| A50083 | 35533489 | Biochem Biophys Res Commun | DDX17 protects hepatocytes against oleic acid/palmitic acid-induced lipid accumulation. | 2022 | Details |
| A50090 | 35531696 | Zhongguo Zhong Yao Za Zhi | [Di'ao Xinxuekang alleviates non-alcoholic steatohepatitis in mice by up-regulating Nrf2/HO-1 signaling pathway]. | 2022 | Details |
| A50092 | 35531334 | Front Cell Infect Microbiol | Yiqi-Bushen-Tiaozhi Recipe Attenuated High-Fat and High-Fructose Diet Induced Nonalcoholic Steatohepatitis in Mice via Gut Microbiota. | 2022 | Details |
| A50101 | 35528835 | Front Cardiovasc Med | Salvia miltiorrhiza Bge. (Danshen) in the Treating Non-alcoholic Fatty Liver Disease Based on the Regulator of Metabolic Targets. | 2022 | Details |
| A50116 | 35517790 | Front Pharmacol | FGF9 Alleviates the Fatty Liver Phenotype by Regulating Hepatic Lipid Metabolism. | 2022 | Details |
| A50118 | 35514751 | Front Med (Lausanne) | SPP1 and CXCL9 Promote Non-alcoholic Steatohepatitis Progression Based on Bioinformatics Analysis and Experimental Studies. | 2022 | Details |
| A50127 | 35510379 | J Food Biochem | Major royal jelly proteins alleviate non-alcoholic fatty liver disease in mice model by regulating disordered metabolic pathways. | 2022 | Details |
| A50133 | 35508252 | Arch Biochem Biophys | Eugenol alleviated nonalcoholic fatty liver disease in rat via a gut-brain-liver axis involving glucagon-like Peptide-1. | 2022 | Details |
| A50135 | 35507845 | Anim Biosci | Severe choline deficiency induces alternative splicing aberrance in optimized duck primary hepatocyte cultures. | 2022 | Details |
| A50143 | 35504134 | Redox Biol | Overexpression of NAG-1/GDF15 prevents hepatic steatosis through inhibiting oxidative stress-mediated dsDNA release and AIM2 inflammasome activation. | 2022 | Details |
| A50180 | 35487948 | Sci Rep | Hibiscus sabdariffa extract improves hepatic steatosis, partially through IRS-1/Akt and Nrf2 signaling pathways in rats fed a high fat diet. | 2022 | Details |
| A50185 | 35485931 | J Agric Food Chem | The Ameliorating Effects of Apple Polyphenol Extract on High-Fat-Diet-Induced Hepatic Steatosis Are SIRT1-Dependent: Evidence from Hepatic-Specific SIRT1 Heterozygous Mutant C57BL/6 Mice. | 2022 | Details |
| A50193 | 35483638 | J Control Release | Celastrol-loaded lactosylated albumin nanoparticles attenuate hepatic steatosis in non-alcoholic fatty liver disease. | 2022 | Details |
| A50217 | 35469167 | JHEP Rep | Lipid alterations in chronic liver disease and liver cancer. | 2022 | Details |
| A50238 | 35462473 | Acta Biochim Biophys Sin (Shanghai) | Ch25h and 25-HC prevent liver steatosis through regulation of cholesterol metabolism and inflammation. | 2022 | Details |
| A50239 | 35462330 | Biomed Pharmacother | Update of Indoles: Promising molecules for ameliorating metabolic diseases. | 2022 | Details |
| A50248 | 35457142 | Int J Mol Sci | Role of Branched-Chain Amino Acid Metabolism in Type 2 Diabetes, Obesity, Cardiovascular Disease and Non-Alcoholic Fatty Liver Disease. | 2022 | Details |
| A50259 | 35451807 | Curr Med Sci | Efficacy of Sitagliptin on Nonalcoholic Fatty Liver Disease in High-fat-diet-fed Diabetic Mice. | 2022 | Details |
| A50268 | 35449197 | Cell Death Discov | HtrA2/Omi mitigates NAFLD in high-fat-fed mice by ameliorating mitochondrial dysfunction and restoring autophagic flux. | 2022 | Details |
| A50273 | 35447899 | Mar Drugs | Fucoxanthin Attenuates Free Fatty Acid-Induced Nonalcoholic Fatty Liver Disease by Regulating Lipid Metabolism/Oxidative Stress/Inflammation via the AMPK/Nrf2/TLR4 Signaling Pathway. | 2022 | Details |
| A50277 | 35447114 | J Biol Chem | Leukemia inhibitory factor protects against liver steatosis in nonalcoholic fatty liver disease patients and obese mice. | 2022 | Details |
| A50306 | 35437549 | Food Funct | L-Methionine supplementation attenuates high-fat fructose diet-induced non-alcoholic steatohepatitis by modulating lipid metabolism, fibrosis, and inflammation in rats. | 2022 | Details |
| A50308 | 35436984 | Cell Death Dis | B-cell lymphoma 6 alleviates nonalcoholic fatty liver disease in mice through suppression of fatty acid transporter CD36. | 2022 | Details |
| A50310 | 35436630 | Biochem Biophys Res Commun | Hydrochloride Berberine ameliorates alcohol-induced liver injury by regulating inflammation and lipid metabolism. | 2022 | Details |
| A50332 | 35430208 | Eur J Pharmacol | The lactate receptor GPR81 mediates hepatic lipid metabolism and the therapeutic effect of metformin on experimental NAFLDs. | 2022 | Details |
| A50338 | 35429042 | FASEB J | Serpina3c deficiency induced necroptosis promotes non-alcoholic fatty liver disease through β-catenin/Foxo1/TLR4 signaling. | 2022 | Details |
| A50341 | 35428541 | Nutr Metab Cardiovasc Dis | Lipids and diastolic dysfunction: Recent evidence and findings. | 2022 | Details |
| A50348 | 35421921 | BMC Microbiol | Characterization of microbiome and metabolite analyses in patients with metabolic associated fatty liver disease and type II diabetes mellitus. | 2022 | Details |
| A50366 | 35416649 | J Agric Food Chem | Pterostilbene and Its Derivative 3'-Hydroxypterostilbene Ameliorated Nonalcoholic Fatty Liver Disease Through Synergistic Modulation of the Gut Microbiota and SIRT1/AMPK Signaling Pathway. | 2022 | Details |
| A50381 | 35410857 | Turk J Gastroenterol | Fibroblast Growth Factor 21 as a Marker of Prediabetes in Patients with Non-alcoholic Fatty Liver Disease. | 2022 | Details |
| A50383 | 35409465 | Int J Environ Res Public Health | Sclerocarya birrea (Marula) Extract Inhibits Hepatic Steatosis in db/db Mice. | 2022 | Details |
| A50384 | 35409319 | Int J Mol Sci | Hepatic PTEN Signaling Regulates Systemic Metabolic Homeostasis through Hepatokines-Mediated Liver-to-Peripheral Organs Crosstalk. | 2022 | Details |
| A50390 | 35407364 | J Clin Med | Improvement of Type 2 Diabetes Mellitus and Attenuation of NAFLD Are Associated with the Success of Obesity Therapy. | 2022 | Details |