Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Diabetes mellitus4971 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A48160 | 20974941 | Proc Natl Acad Sci U S A | Sarco(endo)plasmic reticulum Ca2+-ATPase 2b is a major regulator of endoplasmic reticulum stress and glucose homeostasis in obesity. | 2010 | Details |
| A48176 | 20660066 | Endocrinology | Curcumin protects hepatic stellate cells against leptin-induced activation in vitro by accumulating intracellular lipids. | 2010 | Details |
| A48212 | 19549744 | J Clin Endocrinol Metab | Thyroid hormone-related regulation of gene expression in human fatty liver. | 2009 | Details |
| A48221 | 19399911 | Hepatology | Association between hypothyroidism and hepatocellular carcinoma: a case-control study in the United States. | 2009 | Details |
| A48228 | 19174778 | Am J Gastroenterol | Role of interleukin-6 in human nonalcoholic steatohepatitis. Response to Dogru et al. | 2009 | Details |
| A48242 | 18972558 | Hepatology | Nonalcoholic steatohepatitis is frequently accompanied by metabolic diseases. | 2008 | Details |
| A48261 | 18193132 | J Gastrointestin Liver Dis | Minimally invasive surgical treatment of morbid obesity in patients with specific comorbidities. A case report. | 2007 | Details |
| A48270 | 17940115 | J Clin Endocrinol Metab | Type 1 diabetes associated with acquired generalized lipodystrophy and insulin resistance: the effect of long-term leptin therapy. | 2007 | Details |
| A48274 | 17828789 | Hepatology | Hemochromatosis genotypes and risk of 31 disease endpoints: meta-analyses including 66,000 cases and 226,000 controls. | 2007 | Details |
| A48275 | 17682318 | J Med | Thioacetamide-induced hepatic damage in a rat nutritional model of steatohepatitis. | 2003 | Details |
| A48288 | 17347462 | N Engl J Med | Pioglitazone in nonalcoholic steatohepatitis. | 2007 | Details |
| A48292 | 17241893 | Gastroenterology | Insulin resistance: cause or consequence of nonalcoholic steatohepatitis? | 2007 | Details |
| A48294 | 17135591 | N Engl J Med | Thiazolidinediones for nonalcoholic steatohepatitis--promising but not ready for prime time. | 2006 | Details |
| A48295 | 17135584 | N Engl J Med | A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis. | 2006 | Details |
| A48317 | 30290456 | Expert Rev Endocrinol Metab | Obesity, insulin resistance, Type 2 diabetes and free fatty acids. | 2006 | Details |
| A48319 | 16772767 | Am J Ther | Highly active antiretroviral therapy-associated metabolic syndrome: pathogenesis and cardiovascular risk. | 2006 | Details |
| A48322 | 16617233 | Am J Med Sci | The effect of obesity surgery on obesity comorbidity. | 2006 | Details |
| A48325 | 16522283 | Curr Diab Rep | Metabolic syndrome in the elderly. | 2006 | Details |
| A48329 | 16390234 | Arch Pathol Lab Med | Diabetic hepatosclerosis: diabetic microangiopathy of the liver. | 2006 | Details |
| A48330 | 16378280 | Turk J Gastroenterol | Obesity and related parameters of non-alcoholic steatohepatitis. | 2002 | Details |
| A48336 | 16219720 | J Clin Endocrinol Metab | Thyrotropin suppression by metformin. | 2005 | Details |
| A48338 | 16181372 | Am J Gastroenterol | Hepatic steatosis in Dunnigan-type familial partial lipodystrophy. | 2005 | Details |
| A48342 | 16124712 | Nihon Shokakibyo Gakkai Zasshi | [Type 2 diabetes mellitus with histological finding of nonalcoholic steatohepatitis following combination therapy with interferon and ribavirin for chronic hepatitis C]. | 2005 | Details |
| A48344 | 15918151 | Semin Liver Dis | Benign hepatocellular tumors (adenomatosis) in nonalcoholic steatohepatitis: a case report. | 2005 | Details |
| A48345 | 15835633 | Ned Tijdschr Geneeskd | [Nonalcoholic steatohepatitis: diagnosis, pathogenesis, treatment and prognosis]. | 2005 | Details |
| A48353 | 15588779 | Hepatol Res | Thioacetamide-induced hepatic damage in a rat nutritional model of steatohepatitis. | 2004 | Details |
| A48358 | 15368170 | Dtsch Med Wochenschr | [Nonalcoholic steatohepatitis (NASH): therapeutic approaches]. | 2004 | Details |
| A48370 | 14696453 | Hepatogastroenterology | Clinical characteristics of patients with cryptogenic liver cirrhosis in Okinawa, Japan. | 2004 | Details |
| A48387 | 12811221 | J Clin Gastroenterol | Is hepatocellular carcinoma part of the natural history of nonalcoholic steatohepatitis? | 2003 | Details |
| A48397 | 12544284 | Curr Opin Pediatr | Case report: nonalcoholic steatohepatitis in a teenage girl with type 2 diabetes. | 2003 | Details |
| A48399 | 12527343 | Am J Surg | The extent of the problem of obesity. | 2002 | Details |
| A48403 | 12364344 | Hypertension | Obesity hypertension in children: a problem of epidemic proportions. | 2002 | Details |
| A48413 | 12060674 | FASEB J | Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A. | 2002 | Details |
| A48431 | 11179243 | Gastroenterology | Current status of medical and surgical therapy for obesity. | 2001 | Details |
| A48437 | 10990076 | Diabetologia | Association between microsomal triglyceride transfer protein gene polymorphism and the biological features of liver steatosis in patients with type II diabetes. | 2000 | Details |
| A48443 | 10680276 | Cleve Clin J Med | The spectrum of nonalcoholic fatty liver disease: from steatosis to nonalcoholic steatohepatitis. | 2000 | Details |
| A48444 | 10630439 | J Pediatr Gastroenterol Nutr | Nonalcoholic steatohepatitis in children. | 2000 | Details |
| A48473 | 8581074 | Int J Obes Relat Metab Disord | Liver disturbances in obesity and diabetes mellitus. | 1995 | Details |
| A48474 | 7553425 | Zhonghua Yi Xue Za Zhi (Taipei) | Prevalence of antibodies to hepatitis C virus in patients with nonalcoholic fatty liver. | 1995 | Details |
| A48475 | 7768519 | Hepatology | Nonalcoholic steatohepatitis: tightening the morphological screws on a hepatic rambler. | 1995 | Details |
| A48487 | 3564380 | Vopr Pitan | [Role of modern diet therapy in the prevention of visceral complications in patients with dietary obesity]. | 1987 | Details |
| A48489 | 3988246 | Histopathology | Diabetic hepatitis preceding the onset of glucose intolerance. | 1985 | Details |
| A48494 | 6166516 | Gut | Mallory bodies in alcoholic and non-alcoholic liver disease contain a common antigenic determinant. | 1981 | Details |
| A48495 | 7382552 | Mayo Clin Proc | Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease. | 1980 | Details |
| A48505 | 35158892 | Cancers (Basel) | Hepatocellular Carcinoma: Molecular Pathogenesis and Therapeutic Advances. | 2022 | Details |
| A48525 | 34846697 | Drugs | Chiglitazar: First Approval. | 2022 | Details |
| A48544 | 34364773 | Nutr Metab Cardiovasc Dis | Hepatic fibrosis of any origin in a large population of type 2 diabetes patients. | 2021 | Details |
| A48549 | 34267725 | Front Endocrinol (Lausanne) | Clinical Perspectives on the Use of Subcutaneous and Oral Formulations of Semaglutide. | 2021 | Details |
| A48553 | 34220440 | Front Neurosci | The Potential Role of Inflammation in Modulating Endogenous Hippocampal Neurogenesis After Spinal Cord Injury. | 2021 | Details |
| A48560 | 34093007 | Drug Des Devel Ther | Incidence and Risk Factors of Hepatic Fibrosis in Psoriatic Patients Receiving Methotrexate with Concomitant Acitretin Therapy and Methotrexate Monotherapy. | 2021 | Details |
| A48569 | 33883009 | Diabetol Metab Syndr | Burden of non-alcoholic steatohepatitis among children with type 2 diabetes mellitus. | 2021 | Details |
| A48579 | 33728472 | Trans R Soc Trop Med Hyg | Liver stiffness is able to differentiate hepatosplenic Schistosomiasis mansoni from liver cirrhosis and spleen stiffness may be a predictor of variceal bleeding in hepatosplenic schistosomiasis. | 2022 | Details |
| A48590 | 33479224 | Nat Rev Dis Primers | Hepatocellular carcinoma. | 2021 | Details |
| A48609 | 33158470 | Best Pract Res Clin Gastroenterol | Cardiovascular and metabolic disease in the liver transplant recipient. | 2020 | Details |
| A48616 | 32941717 | Dermatol Online J | Secukinumab-associated localized granuloma annulare (SAGA): a case report and review of the literature. | 2020 | Details |
| A48618 | 32903449 | Front Pharmacol | Therapeutic Efficacy of Antioxidants in Ameliorating Obesity Phenotype and Associated Comorbidities. | 2020 | Details |
| A48696 | 31368881 | Endocr Metab Immune Disord Drug Targets | Key Relevance of Epigenetic Programming of Adiponectin Gene in Pathogenesis of Metabolic Disorders. | 2020 | Details |
| A48701 | 31171906 | Int J Med Sci | MALAT1 as a Diagnostic and Therapeutic Target in Diabetes-Related Complications: A Promising Long-Noncoding RNA. | 2019 | Details |
| A48713 | 30917505 | Int J Mol Sci | Role of SIRT-3, p-mTOR and HIF-1α in Hepatocellular Carcinoma Patients Affected by Metabolic Dysfunctions and in Chronic Treatment with Metformin. | 2019 | Details |
| A48734 | 30324146 | Clin Exp Hepatol | Cellulitis in liver cirrhosis - a series of 25 cases from southern India. | 2018 | Details |
| A48746 | 29926478 | Br J Clin Pharmacol | MEDI0382, a GLP-1/glucagon receptor dual agonist, meets safety and tolerability endpoints in a single-dose, healthy-subject, randomized, Phase 1 study. | 2018 | Details |
| A48758 | 29519261 | Ned Tijdschr Geneeskd | [EndoBarrier as a treatment for obesity and diabetes]. | 2018 | Details |
| A48799 | 28357101 | Mol Clin Oncol | Laparoscopic hepatectomy in a morbidly obese patient with liver cirrhosis: A case report. | 2016 | Details |
| A48805 | 30802391 | Klin Lab Diagn | [The chronic hepatitis under pulmonary, extra-pulmonary and abdominal tuberculosis.] | 2019 | Details |
| A48811 | 27775791 | Eur Rev Med Pharmacol Sci | Association between irisin and major chronic diseases: a review. | 2016 | Details |
| A48819 | 27639537 | Lancet Diabetes Endocrinol | Clinical relevance of the bile acid receptor TGR5 in metabolism. | 2016 | Details |
| A48850 | 26680665 | Physiol Res | Fasting and nonfasting triglycerides in cardiovascular and other diseases. | 2015 | Details |
| A48884 | 25673576 | Br J Anaesth | Acute kidney injury following orthotopic liver transplantation: incidence, risk factors, and effects on patient and graft outcomes. | 2015 | Details |
| A48899 | 25230385 | Rozhl Chir | Bariatric metabolic surgery. | 2014 | Details |
| A48900 | 25126389 | World J Diabetes | Pancreatic steatosis: Is it related to either obesity or diabetes mellitus? | 2014 | Details |
| A48904 | 25040315 | Aliment Pharmacol Ther | The impact of type 2 diabetes and obesity on the long-term outcomes of more than 85 000 liver transplant recipients in the US. | 2014 | Details |
| A48910 | 24804175 | Liver Cancer | Hepatic iron overload and hepatocellular carcinoma. | 2014 | Details |
| A48913 | 24747242 | Sci Total Environ | Obesity-mediated association between exposure to brominated trihalomethanes and type II diabetes mellitus: an exploratory analysis. | 2014 | Details |
| A48920 | 24438608 | Chin Med J (Engl) | Fasudil hydrochloride hydrate, a Rho-kinase inhibitor, ameliorates hepatic fibrosis in rats with type 2 diabetes. | 2014 | Details |
| A48935 | 23937266 | Hepatol Res | Pathological characteristics of patients who develop hepatocellular carcinoma with negative results of both serous hepatitis B surface antigen and hepatitis C virus antibody. | 2013 | Details |
| A48940 | 23768554 | Best Pract Res Clin Gastroenterol | Diabetes, obesity and gut microbiota. | 2013 | Details |
| A48942 | 23700549 | Adipocyte | Valsartan restores inflammatory response by macrophages in adipose and hepatic tissues of LPS-infused mice. | 2013 | Details |
| A48970 | 22819910 | Hepatogastroenterology | Features and outcome after liver resection for non-B non-C hepatocellular carcinoma. | 2012 | Details |
| A48971 | 22801434 | Panminerva Med | Metabolic derangements mediate cognitive impairment and Alzheimer's disease: role of peripheral insulin-resistance diseases. | 2012 | Details |
| A48978 | 22452372 | Br J Pharmacol | Curcumin ameliorates hepatic fibrosis in type 2 diabetes mellitus - insights into its mechanisms of action. | 2012 | Details |
| A48979 | 22449800 | Lab Invest | Curcumin eliminates the inhibitory effect of advanced glycation end-products (AGEs) on gene expression of AGE receptor-1 in hepatic stellate cells in vitro. | 2012 | Details |
| A48983 | 22352842 | Br J Pharmacol | Curcumin inhibits gene expression of receptor for advanced glycation end-products (RAGE) in hepatic stellate cells in vitro by elevating PPARγ activity and attenuating oxidative stress. | 2012 | Details |
| A49004 | 21612060 | Vnitr Lek | [Diabetes mellitus and the liver cirrhosis]. | 2011 | Details |
| A49013 | 21329534 | Ned Tijdschr Geneeskd | [Diabetes mellitus and cirrhosis of the liver: a prognostically unfavourable combination]. | 2011 | Details |
| A49019 | 21150335 | Oxid Med Cell Longev | Atorvastatin reduces proteinuria in non-diabetic chronic kidney disease patients partly via lowering serum levels of advanced glycation end products (AGEs). | 2010 | Details |
| A49021 | 21131943 | Am J Gastroenterol | Exenatide in the treatment of diabetic patients with non-alcoholic steatohepatitis: a case series. | 2010 | Details |
| A49028 | 20953861 | Diabetologia | Targeting energy expenditure via fuel switching and beyond. | 2010 | Details |
| A49036 | 20570793 | Orv Hetil | [Role of environmental factors in the etiology of hepatocellular carcinoma]. | 2010 | Details |
| A49054 | 19906067 | Cancer Sci | Dietary supplementation with branched-chain amino acids suppresses diethylnitrosamine-induced liver tumorigenesis in obese and diabetic C57BL/KsJ-db/db mice. | 2009 | Details |
| A49066 | 19538246 | Diabet Med | Insulin resistance and endothelial dysfunction in type 2 diabetic patients with non-alcoholic steatohepatitis. | 2009 | Details |
| A49070 | 19255916 | Crit Rev Clin Lab Sci | The paraoxonases: role in human diseases and methodological difficulties in measurement. | 2009 | Details |
| A49079 | 18793162 | Biochem Soc Trans | NOX family NADPH oxidases in liver and in pancreatic islets: a role in the metabolic syndrome and diabetes? | 2008 | Details |
| A49082 | 18626433 | Ann Hepatol | Impact of diabetes mellitus on outcome of HCC. | 2008 | Details |
| A49111 | 17339155 | J Formos Med Assoc | Pancreaticobiliary anomalies is the leading cause of childhood recurrent pancreatitis. | 2007 | Details |
| A49114 | 17198075 | J Clin Gastroenterol | Abnormal glucose tolerance and non-esterified fatty acids (NEFAs) as predictors of non-alcoholic steatohepatitis (NASH): which Ash that ignites the NASH. | 2007 | Details |
| A49126 | 16610061 | World J Gastroenterol | Cryptogenic cirrhosis in the region where obesity is not prevalent. | 2006 | Details |
| A49147 | 16225471 | Aliment Pharmacol Ther | Review article: steatosis, the metabolic syndrome and cancer. | 2005 | Details |
| A49150 | 16208305 | Minerva Endocrinol | The metabolic syndrome and type 2 diabetes. | 2005 | Details |
| A49162 | 15724606 | Lik Sprava | [Changes in indices of connective tissue in patients with alcoholic and non-alcoholic steatohepatitis and their correction with glutargin]. | 2005 | Details |
| A49167 | 15649101 | Treat Endocrinol | Surgical management of obesity: a review of the evidence relating to the health benefits and risks. | 2005 | Details |