Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A50391 | 35407014 | Foods | Tilapia-Head Chondroitin Sulfate Protects against Nonalcoholic Fatty Liver Disease via Modulating the Gut-Liver Axis in High-Fat-Diet-Fed C57BL/6 Mice. | 2022 | Details |
| A50392 | 35406736 | Cells | Multi-Omics Approach Reveals Dysregulation of Protein Phosphorylation Correlated with Lipid Metabolism in Mouse Non-Alcoholic Fatty Liver. | 2022 | Details |
| A50394 | 35406631 | Cells | Psoralen Suppresses Lipid Deposition by Alleviating Insulin Resistance and Promoting Autophagy in Oleate-Induced L02 Cells. | 2022 | Details |
| A50397 | 35405942 | Nutrients | Investigation of the Effect of Curcumin on Protein Targets in NAFLD Using Bioinformatic Analysis. | 2022 | Details |
| A50400 | 35405150 | Metabolism | Schisandrin B mitigates hepatic steatosis and promotes fatty acid oxidation by inducing autophagy through AMPK/mTOR signaling pathway. | 2022 | Details |
| A50411 | 35400330 | Endocr Metab Immune Disord Drug Targets | Literature Review on the Use of Herbal Extracts in the Treatment of Non-Alcoholic Fatty Liver Disease. | 2022 | Details |
| A50418 | 35398611 | Biochem Biophys Res Commun | Abietic acid alleviates endoplasmic reticulum stress and lipid accumulation in human primary hepatocytes through the AMPK/ORP150 signaling. | 2022 | Details |
| A50425 | 35396857 | J Food Biochem | Comparative effects of sesame lignans (sesamin, sesamolin, and sesamol) on oxidative stress and lipid metabolism in steatosis HepG2 cells. | 2022 | Details |
| A50432 | 35394671 | FASEB J | Hepatic lipid accumulation induced by a high-fat diet is regulated by Nrf2 through multiple pathways. | 2022 | Details |
| A50434 | 35394106 | Chem Biodivers | Dihydroflavonoids as Bioactive Components of Penthorum chinense, a Miao Ethnomedicine, against NAFLD through Bile Acid Metabolism Pathway. | 2022 | Details |
| A50443 | 35389416 | Food Funct | Structural characterization and preventive effect on non-alcoholic fatty liver disease of oligosaccharides from Bletilla striata. | 2022 | Details |
| A50463 | 35381388 | Mol Metab | Proteomic analysis reveals exercise training induced remodelling of hepatokine secretion and uncovers syndecan-4 as a regulator of hepatic lipid metabolism. | 2022 | Details |
| A50475 | 35372814 | iScience | The vesicular transporter STX11 governs ATGL-mediated hepatic lipolysis and lipophagy. | 2022 | Details |
| A50485 | 35367665 | Cell Mol Gastroenterol Hepatol | Macrophage SCAP Contributes to Metaflammation and Lean NAFLD by Activating STING-NF-κB Signaling Pathway. | 2022 | Details |
| A50486 | 35367353 | Biochim Biophys Acta Mol Cell Biol Lipids | Nudix hydrolase NUDT19 regulates mitochondrial function and ATP production in murine hepatocytes. | 2022 | Details |
| A50487 | 35367244 | Life Sci | Exercise regulation of hepatic lipid droplet metabolism. | 2022 | Details |
| A50497 | 35364708 | Nat Prod Bioprospect | Indole alkaloids of Alstonia scholaris (L.) R. Br. alleviated nonalcoholic fatty liver disease in mice fed with high-fat diet. | 2022 | Details |
| A50510 | 35358801 | Biomed Pharmacother | Bioinformatics study of the potential therapeutic effects of ginsenoside Rf in reversing nonalcoholic fatty liver disease. | 2022 | Details |
| A50511 | 35358477 | Biochem Pharmacol | Valdecoxib attenuates lipid-induced hepatic steatosis through autophagy-mediated suppression of endoplasmic reticulum stress. | 2022 | Details |
| A50512 | 35357518 | Naunyn Schmiedebergs Arch Pharmacol | Phytochemicals targeting NAFLD through modulating the dual function of forkhead box O1 (FOXO1) transcription factor signaling pathways. | 2022 | Details |
| A50517 | 35355551 | Front Endocrinol (Lausanne) | Non-Alcoholic Fatty Liver Disease in HIV/HBV Patients - a Metabolic Imbalance Aggravated by Antiretroviral Therapy and Perpetuated by the Hepatokine/Adipokine Axis Breakdown. | 2022 | Details |
| A50520 | 35354841 | Sci Rep | Aerobic exercise promotes the expression of ATGL and attenuates inflammation to improve hepatic steatosis via lncRNA SRA. | 2022 | Details |
| A50532 | 35351574 | J Ethnopharmacol | Pretreatment of hydroethanolic extract of Dillenia indica L. attenuates oleic acid induced NAFLD in HepG2 cells via modulating SIRT-1/p-LKB-1/AMPK, HMGCR & PPAR-α signaling pathways. | 2022 | Details |
| A50556 | 35343085 | Clin Transl Med | MD2 deficiency prevents high-fat diet-induced AMPK suppression and lipid accumulation through regulating TBK1 in non-alcoholic fatty liver disease. | 2022 | Details |
| A50557 | 35341816 | Environ Pollut | Early-life exposure to bisphenol A induces dysregulation of lipid homeostasis by the upregulation of SCD1 in male mice. | 2022 | Details |
| A50569 | 35335339 | Molecules | Garcinia Biflavonoid 1 Improves Lipid Metabolism in HepG2 Cells via Regulating PPARα. | 2022 | Details |
| A50581 | 35333579 | Sci Adv | Nuclear HMGB1 protects from nonalcoholic fatty liver disease through negative regulation of liver X receptor. | 2022 | Details |
| A50594 | 35330105 | Life (Basel) | Taurine Ameliorates Tunicamycin-Induced Liver Injury by Disrupting the Vicious Cycle between Oxidative Stress and Endoplasmic Reticulum Stress. | 2022 | Details |
| A50595 | 35329997 | J Clin Med | Heparanase Inhibition Prevents Liver Steatosis in E0 Mice. | 2022 | Details |
| A50599 | 35328587 | Int J Mol Sci | Usefulness of Probiotics in the Management of NAFLD: Evidence and Involved Mechanisms of Action from Preclinical and Human Models. | 2022 | Details |
| A50611 | 35326230 | Antioxidants (Basel) | Combination Effects of Metformin and a Mixture of Lemon Balm and Dandelion on High-Fat Diet-Induced Metabolic Alterations in Mice. | 2022 | Details |
| A50612 | 35326122 | Antioxidants (Basel) | Lingonberry Improves Hepatic Lipid Metabolism by Targeting Notch1 Signaling. | 2022 | Details |
| A50621 | 35323719 | Medicines (Basel) | Salubrious Effects of Green Tea Catechins on Fatty Liver Disease: A Systematic Review. | 2022 | Details |
| A50653 | 35313531 | Metabol Open | Acute intermittent hypoxia drives hepatic de novo lipogenesis in humans and rodents. | 2022 | Details |
| A50659 | 35311663 | Metabolism | Sterol carrier protein 2 in lipid metabolism and non-alcoholic fatty liver disease: Pathophysiology, molecular biology, and potential clinical implications. | 2022 | Details |
| A50668 | 35308224 | Front Pharmacol | Pharmacological Effects and Molecular Protective Mechanisms of Astragalus Polysaccharides on Nonalcoholic Fatty Liver Disease. | 2022 | Details |
| A50671 | 35307486 | Cancer Lett | Sperm associated antigen 4 promotes SREBP1-mediated de novo lipogenesis via interaction with lamin A/C and contributes to tumor progression in hepatocellular carcinoma. | 2022 | Details |
| A50678 | 35305493 | Biochem Biophys Res Commun | Transcriptomic analysis reveals a novel regulatory factor of ECHDC1 involved in lipid metabolism of non-alcoholic fatty liver disease. | 2022 | Details |
| A50681 | 35304272 | J Ethnopharmacol | Antrodia cinnamomea and its compound dehydroeburicoic acid attenuate nonalcoholic fatty liver disease by upregulating ALDH2 activity. | 2022 | Details |
| A50682 | 35304191 | Mol Cell Endocrinol | Enterohepatic and non-canonical roles of farnesoid X receptor in controlling lipid and glucose metabolism. | 2022 | Details |
| A50713 | 35290413 | PLoS One | Abelmoschus esculentus subfractions ameliorate hepatic lipogenesis and lipid uptake via regulating dipeptidyl peptidase-4-With improving insulin resistance. | 2022 | Details |
| A50737 | 35283218 | Mol Cell Endocrinol | Discovery of farnesoid X receptor and its role in bile acid metabolism. | 2022 | Details |
| A50739 | 35283114 | Gastroenterology | Postprandial Plasma Lipidomics Reveal Specific Alteration of Hepatic-derived Diacylglycerols in Nonalcoholic Fatty Liver Disease. | 2022 | Details |
| A50740 | 35282837 | Lipids Health Dis | Fat mass and obesity-associated protein promotes liver steatosis by targeting PPARα. | 2022 | Details |
| A50746 | 35280674 | Int J Biol Sci | Atractylenolide III ameliorates Non-Alcoholic Fatty Liver Disease by activating Hepatic Adiponectin Receptor 1-Mediated AMPK Pathway. | 2022 | Details |
| A50748 | 35278877 | Biochem Biophys Res Commun | Aerobic exercise improves non-alcoholic fatty liver disease by down-regulating the protein expression of the CNPY2-PERK pathway. | 2022 | Details |
| A50750 | 35278405 | Eur J Pharmacol | Inonotus obliquus and its bioactive compounds alleviate non-alcoholic fatty liver disease via regulating FXR/SHP/SREBP-1c axis. | 2022 | Details |
| A50769 | 35273160 | Nat Commun | Deep proteomic profiling unveils arylsulfatase A as a non-alcoholic steatohepatitis inducible hepatokine and regulator of glycemic control. | 2022 | Details |
| A50780 | 35269515 | Cells | Transcriptomics Reveals Discordant Lipid Metabolism Effects between In Vitro Models Exposed to Elafibranor and Liver Samples of NAFLD Patients after Bariatric Surgery. | 2022 | Details |
| A50785 | 35268076 | Nutrients | The Effect of Dietary Interventions on Hypertriglyceridemia: From Public Health to Molecular Nutrition Evidence. | 2022 | Details |
| A50791 | 35265044 | Front Endocrinol (Lausanne) | Comprehensive Transcriptome Profiling of NAFLD- and NASH-Induced Skeletal Muscle Dysfunction. | 2022 | Details |
| A50794 | 35263694 | Clin Nutr | Maternal polyunsaturated fatty acid concentrations during pregnancy and childhood liver fat accumulation. | 2022 | Details |
| A50795 | 35263689 | Clin Nutr | Fatty acids in multiple circulating lipid fractions reflects the composition of liver triglycerides in humans. | 2022 | Details |
| A50872 | 34723832 | J Mol Endocrinol | miR-23a/b-3p promotes hepatic lipid accumulation by regulating Srebp-1c and Fas. | 2021 | Details |
| A50924 | 35296120 | Front Toxicol | Diet as an Exposure Source and Mediator of Per- and Polyfluoroalkyl Substance (PFAS) Toxicity. | 2020 | Details |
| A50943 | 35540668 | RSC Adv | Nifuroxazide ameliorates lipid and glucose metabolism in palmitate-induced HepG2 cells. | 2019 | Details |
| A50963 | 35559112 | RSC Adv | Proteomics for studying the effects of L. rhamnosus LV108 against non-alcoholic fatty liver disease in rats. | 2018 | Details |
| A51027 | 23982685 | Nat Rev Gastroenterol Hepatol | Liver: Caffeine is a potent stimulator of autophagy to reduce hepatic lipid content--a coffee for NAFLD? | 2013 | Details |
| A51059 | 19015652 | Nat Clin Pract Gastroenterol Hepatol | What advice should be given to patients with NAFLD about the consumption of alcohol? | 2008 | Details |
| A51061 | 17911352 | Gut | Benefits of lifestyle modification in NAFLD. | 2007 | Details |
| A51100 | 35766964 | J Med Food | Persimmon Water Extract Suppresses Hepatic Lipotoxicity by Regulating Lipid Metabolites. | 2022 | Details |
| A51121 | 35658903 | Mol Neurodegener | TREM2 in the pathogenesis of AD: a lipid metabolism regulator and potential metabolic therapeutic target. | 2022 | Details |
| A51142 | 35511325 | J Microbiol | Host-microbial interactions in metabolic diseases: from diet to immunity. | 2022 | Details |
| A51148 | 35470867 | J Food Biochem | Dietary sinapic acid attenuated high-fat diet-induced lipid metabolism and oxidative stress in male Syrian hamsters. | 2022 | Details |
| A51149 | 35469640 | J Dairy Sci | Role of sortilin 1 (SORT1) on lipid metabolism in bovine liver. | 2022 | Details |
| A51157 | 35447117 | J Biol Chem | Calpain-mediated proteolytic production of free amino acids in vascular endothelial cells augments obesity-induced hepatic steatosis. | 2022 | Details |
| A51159 | 35432002 | Front Physiol | The Cardiovascular and Metabolic Effects of Chronic Hypoxia in Animal Models: A Mini-Review. | 2022 | Details |
| A51161 | 35427802 | Clin Res Hepatol Gastroenterol | The mTORC1/AMPK pathway plays a role in the beneficial effects of semaglutide (GLP-1 receptor agonist) on the liver of obese mice. | 2022 | Details |
| A51177 | 35355504 | Neuropsychiatr Dis Treat | Early Lipid Metabolic Effects of the Anti-Psychotic Drug Olanzapine on Weight Gain and the Associated Gene Expression. | 2022 | Details |
| A51182 | 35323680 | Metabolites | Plasma Tsukushi Concentration Is Associated with High Levels of Insulin and FGF21 and Low Level of Total Cholesterol in a General Population without Medication. | 2022 | Details |
| A51186 | 35296424 | Biochim Biophys Acta Mol Cell Biol Lipids | Mechanisms of intestinal triacylglycerol synthesis. | 2022 | Details |
| A51244 | 5423890 | Gastroenterology | Diminished micellar phase lipid in patients with chronic nonalcoholic liver disease and steatorrhea. | 1970 | Details |
| A51248 | 35464439 | Front Immunol | D-Mannose Regulates Hepatocyte Lipid Metabolism via PI3K/Akt/mTOR Signaling Pathway and Ameliorates Hepatic Steatosis in Alcoholic Liver Disease. | 2022 | Details |
| A51252 | 35274962 | J Proteome Res | Metabolic Signature of Ethanol-Induced Hepatotoxicity in HepaRG Cells by Liquid Chromatography-Mass Spectrometry-Based Untargeted Metabolomics. | 2022 | Details |
| A51278 | 7020988 | Circulation | Lipid and lipoprotein abnormalities in alcoholic liver disease. | 1981 | Details |
| A51279 | 7187287 | Computertomographie | [Computer tomographic studies on the dynamics of liposynthesis and lipolysis of the human liver]. | 1981 | Details |
| A51282 | 87483 | J Lipid Res | Effects of ethanol on lipid metabolism. | 1979 | Details |
| A51289 | 240742 | Fed Proc | Differences in hepatic and metabolic changes after acute and chronic alcohol consumption. | 1975 | Details |
| A51306 | 35735253 | Hepatol Commun | Combinations of an acetyl CoA carboxylase inhibitor with hepatic lipid modulating agents do not augment antifibrotic efficacy in preclinical models of NASH and fibrosis. | 2022 | Details |
| A51309 | 35711841 | J Cancer | Research progress in the role and mechanism of LPCAT3 in metabolic related diseases and cancer. | 2022 | Details |
| A51322 | 35625520 | Biology (Basel) | PPAR Alpha as a Metabolic Modulator of the Liver: Role in the Pathogenesis of Nonalcoholic Steatohepatitis (NASH). | 2022 | Details |
| A51327 | 35592421 | Front Pharmacol | Scoparone Improves Nonalcoholic Steatohepatitis Through Alleviating JNK/Sab Signaling Pathway-Mediated Mitochondrial Dysfunction. | 2022 | Details |
| A51330 | 35559132 | ACS Omega | Lipidomics Revealed Alteration of the Sphingolipid Metabolism in the Liver of Nonalcoholic Steatohepatitis Mice Treated with Scoparone. | 2022 | Details |
| A51337 | 35507418 | J Med Chem | Discovery of a Highly Selective and H435R-Sensitive Thyroid Hormone Receptor β Agonist. | 2022 | Details |
| A51357 | 35332108 | Aging (Albany NY) | Mitophagy and mitochondrial dynamics in type 2 diabetes mellitus treatment. | 2022 | Details |
| A51359 | 35308208 | Front Pharmacol | Therapeutic Effects of Berberine on Liver Fibrosis are associated With Lipid Metabolism and Intestinal Flora. | 2022 | Details |
| A51390 | 35548714 | RSC Adv | SKLB023 as an iNOS inhibitor alleviated liver fibrosis by inhibiting the TGF-beta/Smad signaling pathway. | 2018 | Details |
| A51395 | 35830259 | FASEB J | Intervention with isoleucine or valine corrects hyperinsulinemia and reduces intrahepatic diacylglycerols, liver steatosis, and inflammation in Ldlr-/-.Leiden mice with manifest obesity-associated NASH. | 2022 | Details |
| A51412 | 35709720 | Semin Liver Dis | Non-Alcoholic Steatohepatitis Drug Development Pipeline: An Update. | 2022 | Details |
| A51452 | 35292349 | J Hepatol | Role of XBP1 in regulating the progression of non-alcoholic steatohepatitis. | 2022 | Details |
| A51478 | 30556637 | IUBMB Life | Vitamin E: Regulatory Role on Signal Transduction. | 2018 | Details |
| A51504 | 35770186 | Front Physiol | Extracellular Vesicles in Pathogenesis and Treatment of Metabolic Associated Fatty Liver Disease. | 2022 | Details |
| A51510 | 35720187 | Oxid Med Cell Longev | Melatonin Alleviates PM2.5-Induced Hepatic Steatosis and Metabolic-Associated Fatty Liver Disease in ApoE-/- Mice. | 2022 | Details |
| A51548 | 35290904 | Redox Biol | Mitochondrial depletion of glutaredoxin 2 induces metabolic dysfunction-associated fatty liver disease in mice. | 2022 | Details |
| A51583 | 34869329 | Front Cell Dev Biol | Combined Analysis of Expression Profiles in a Mouse Model and Patients Identified BHMT2 as a New Regulator of Lipid Metabolism in Metabolic-Associated Fatty Liver Disease. | 2021 | Details |
| A51621 | 35550438 | Drug Discov Today | Key regulatory miRNAs in lipid homeostasis: Implications for cardiometabolic diseases and development of novel therapeutics. | 2022 | Details |
| A51625 | 35498747 | Front Vet Sci | Protective Effects of Abrus cantoniensis Hance on the Fatty Liver Hemorrhagic Syndrome in Laying Hens Based on Liver Metabolomics and Gut Microbiota. | 2022 | Details |
| A51626 | 35495929 | Front Nutr | Astaxanthin From Haematococcus pluvialis Prevents High-Fat Diet-Induced Hepatic Steatosis and Oxidative Stress in Mice by Gut-Liver Axis Modulating Properties. | 2022 | Details |
| A51630 | 35483558 | Biochim Biophys Acta Mol Cell Biol Lipids | The effect of black seed (Nigella sativa) extract on lipid metabolism in HepG2 cells. | 2022 | Details |
| A51633 | 35473811 | Br J Nutr | Metabolic adaptation to high starch diet in largemouth bass (Micropterus salmoides) was associated with the restoration of metabolic functions via inflammation, bile acid synthesis and energy metabolism. | 2022 | Details |