Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A20092 | 26160474 | Clin Res Hepatol Gastroenterol | Novel therapeutic targets for steatohepatitis. | 2015 | Details |
| A20094 | 26159280 | Dig Dis | Challenges and Management of Liver Cirrhosis: Practical Issues in the Therapy of Patients with Cirrhosis due to NAFLD and NASH. | 2015 | Details |
| A20100 | 26155043 | J Clin Exp Hepatol | The Riddle of Nonalcoholic Fatty Liver Disease: Progression From Nonalcoholic Fatty Liver to Nonalcoholic Steatohepatitis. | 2015 | Details |
| A20102 | 26154274 | Menopause | Association between nonalcoholic fatty liver disease and coronary artery calcification in postmenopausal women. | 2015 | Details |
| A20106 | 26151226 | Clin Biochem | Gut-liver axis, nutrition, and non-alcoholic fatty liver disease. | 2015 | Details |
| A20111 | 26148225 | Liver Int | I148M variant in PNPLA3 reduces central adiposity and metabolic disease risks while increasing nonalcoholic fatty liver disease. | 2015 | Details |
| A20115 | 26147081 | Nature | The CREB coactivator CRTC2 controls hepatic lipid metabolism by regulating SREBP1. | 2015 | Details |
| A20119 | 26140093 | World J Hepatol | Non-alcoholic fatty liver disease and beneficial effects of dietary supplements. | 2015 | Details |
| A20122 | 26140084 | World J Hepatol | Systematic review: Preventive and therapeutic applications of metformin in liver disease. | 2015 | Details |
| A20124 | 26139990 | World J Gastroenterol | Altered distribution of regulatory lymphocytes by oral administration of soy-extracts exerts a hepatoprotective effect alleviating immune mediated liver injury, non-alcoholic steatohepatitis and insulin resistance. | 2015 | Details |
| A20133 | 26134926 | Expert Opin Drug Saf | Evaluating the safety of Liptruzet (ezetimibe and atorvastatin): what are the potential benefits beyond low-density lipoprotein cholesterol-lowering effect? | 2015 | Details |
| A20136 | 26133820 | Zhonghua Gan Zang Bing Za Zhi | [Effects of telmisartan on resistin expression in a rat model of nonalcoholic steatohepatitis and insulin resistance]. | 2015 | Details |
| A20137 | 26133486 | Int J Mol Med | Treatment with PPARδ agonist alleviates non-alcoholic fatty liver disease by modulating glucose and fatty acid metabolic enzymes in a rat model. | 2015 | Details |
| A20141 | 26132376 | Pediatr Obes | Non-Alcoholic Fatty Liver Disease (NAFLD) in children and adolescents with Prader-Willi Syndrome (PWS). | 2015 | Details |
| A20144 | 26126685 | Am J Physiol Endocrinol Metab | Characterization of lipid metabolism in a novel immortalized human hepatocyte cell line. | 2015 | Details |
| A20146 | 26124760 | Front Immunol | Role of Macrophage Migration Inhibitory Factor in Obesity, Insulin Resistance, Type 2 Diabetes, and Associated Hepatic Co-Morbidities: A Comprehensive Review of Human and Rodent Studies. | 2015 | Details |
| A20148 | 26123841 | Liver Int | Hyperinsulinaemia and insulin signalling in the pathogenesis and the clinical course of hepatocellular carcinoma. | 2015 | Details |
| A20153 | 26120587 | Biomed Res Int | Nonalcoholic Fatty Liver Disease Relationship with Metabolic Syndrome in Class III Obesity Individuals. | 2015 | Details |
| A20157 | 26117210 | Vascul Pharmacol | Decreased plasma endogenous soluble RAGE, and enhanced adipokine secretion, oxidative stress and platelet/coagulative activation identify non-alcoholic fatty liver disease among patients with familial combined hyperlipidemia and/or metabolic syndrome. | 2015 | Details |
| A20168 | 26114083 | Curr Hepatol Rep | PATHOGENESIS OF HEPATOCELLULAR CARCINOMA DEVELOPMENT IN NON ALCOHOLIC FATTY LIVER DISEASE. | 2015 | Details |
| A20181 | 26102213 | Nutrients | Hepatic Steatosis as a Marker of Metabolic Dysfunction. | 2015 | Details |
| A20186 | 26098879 | PLoS One | Fructose Mediated Non-Alcoholic Fatty Liver Is Attenuated by HO-1-SIRT1 Module in Murine Hepatocytes and Mice Fed a High Fructose Diet. | 2015 | Details |
| A20187 | 26097608 | Int J Clin Exp Pathol | Interactions of central obesity with rs3918242 on risk of non-alcoholic fat liver disease: a preliminary case-control study. | 2015 | Details |
| A20190 | 26094890 | Cell Metab | Jejunal T Cell Inflammation in Human Obesity Correlates with Decreased Enterocyte Insulin Signaling. | 2015 | Details |
| A20191 | 26090879 | Int J Sports Med | Simple Resistance Exercise helps Patients with Non-alcoholic Fatty Liver Disease. | 2015 | Details |
| A20192 | 26090514 | ScientificWorldJournal | Histologic and Metabolic Derangement in High-Fat, High-Fructose, and Combination Diet Animal Models. | 2015 | Details |
| A20193 | 26090470 | Biomed Res Int | How Inflammation Impinges on NAFLD: A Role for Kupffer Cells. | 2015 | Details |
| A20194 | 26090468 | Biomed Res Int | Gut Microbiota: Association with NAFLD and Metabolic Disturbances. | 2015 | Details |
| A20197 | 26090093 | J Nutr Sci | Assessment of cardiometabolic risk in children in population studies: underpinning developmental origins of health and disease mother-offspring cohort studies. | 2015 | Details |
| A20205 | 26085904 | World J Hepatol | Understanding the pathophysiological mechanisms in the pediatric non-alcoholic fatty liver disease: The role of genetics. | 2015 | Details |
| A20212 | 26080905 | Minerva Gastroenterol Dietol | The diagnosis and treatment of non-alcoholic fatty liver disease. | 2015 | Details |
| A20220 | 26078565 | World J Gastroenterol | Nonalcoholic fatty liver disease, spleen and psoriasis: New aspects of low-grade chronic inflammation. | 2015 | Details |
| A20227 | 26077675 | J Transl Med | Progression of non-alcoholic steatosis to steatohepatitis and fibrosis parallels cumulative accumulation of danger signals that promote inflammation and liver tumors in a high fat-cholesterol-sugar diet model in mice. | 2015 | Details |
| A20229 | 26076562 | Rom J Intern Med | Noninvasive Markers of Improvement of Liver Steatosis Achieved by Weight Reduction in Patients with Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A20233 | 26073454 | Prog Lipid Res | Strategies, models and biomarkers in experimental non-alcoholic fatty liver disease research. | 2015 | Details |
| A20240 | 26069285 | Thorax | Altered gut-liver axis and hepatic adiponectin expression in OSAS: novel mediators of liver injury in paediatric non-alcoholic fatty liver. | 2015 | Details |
| A20243 | 26066519 | Toxicology | A Northern contaminant mixture impairs pancreas function in obese and lean JCR rats and inhibits insulin secretion in MIN6 cells. | 2015 | Details |
| A20246 | 26064858 | J Lifestyle Med | SIRT3 as a Regulator of Non-alcoholic Fatty Liver Disease. | 2014 | Details |
| A20254 | 26062078 | Eur J Gastroenterol Hepatol | Neutrophil-to-lymphocyte ratio is not a predictor of liver histology in patients with nonalcoholic fatty liver disease. | 2015 | Details |
| A20259 | 26058864 | Am J Physiol Endocrinol Metab | Cross-talk between branched-chain amino acids and hepatic mitochondria is compromised in nonalcoholic fatty liver disease. | 2015 | Details |
| A20264 | 26056025 | J Bone Miner Metab | Circulating sclerostin and Dickkopf-1 levels in patients with nonalcoholic fatty liver disease. | 2015 | Details |
| A20266 | 26055348 | Nutr Res | Resveratrol prevents hepatic steatosis and endoplasmic reticulum stress and regulates the expression of genes involved in lipid metabolism, insulin resistance, and inflammation in rats. | 2015 | Details |
| A20268 | 26052390 | World J Hepatol | Peroxisome proliferator-activated receptors as targets to treat non-alcoholic fatty liver disease. | 2015 | Details |
| A20270 | 26052382 | World J Hepatol | Non-alcoholic fatty liver disease - the heart of the matter. | 2015 | Details |
| A20271 | 26052378 | World J Hepatol | Oxidative stress: New insights on the association of non-alcoholic fatty liver disease and atherosclerosis. | 2015 | Details |
| A20272 | 26052375 | World J Hepatol | Pathophysiological mechanisms involved in non-alcoholic steatohepatitis and novel potential therapeutic targets. | 2015 | Details |
| A20276 | 26049707 | Eur J Gastroenterol Hepatol | Noninvasive estimation of disease activity and liver fibrosis in nonalcoholic fatty liver disease using anthropometric and biochemical characteristics, including insulin, insulin resistance, and 13C-methionine breath test. | 2015 | Details |
| A20277 | 26049666 | Clin Investig Arterioscler | [Role of metabolic lipases and lipotoxicity in the development of non-alcoholic steatosis and non-alcoholic steatohepatitis]. | 2015 | Details |
| A20278 | 26049073 | Semin Thromb Hemost | Vascular Disease in Patients with Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A20279 | 26047899 | Int J Biol Macromol | Protective effects of Ginkgo biloba leaf polysaccharide on nonalcoholic fatty liver disease and its mechanisms. | 2015 | Details |
| A20288 | 26045279 | Dig Dis | Use of farnesoid X receptor agonists to treat nonalcoholic fatty liver disease. | 2015 | Details |
| A20291 | 26043290 | Eur J Gastroenterol Hepatol | Efficacy of rifaximin on circulating endotoxins and cytokines in patients with nonalcoholic fatty liver disease. | 2015 | Details |
| A20292 | 26042770 | PLoS One | mTORC1 Down-Regulates Cyclin-Dependent Kinase 8 (CDK8) and Cyclin C (CycC). | 2015 | Details |
| A20298 | 26040357 | Nutr Hosp | Predictive factors of non-alcoholic steatohepatitis: relationship with metabolic syndrome. | 2015 | Details |
| A20300 | 26039829 | Arq Gastroenterol | Prevalence of non-alcoholic fatty liver disease in women with polycystic ovary syndrome and its correlation with metabolic syndrome. | 2016 | Details |
| A20301 | 26039828 | Arq Gastroenterol | Nonalcoholic fatty liver disease in patients with coronary disease from a Brazil northeast area. | 2016 | Details |
| A20302 | 26039731 | PLoS One | Intravenous Mycobacterium Bovis Bacillus Calmette-Guérin Ameliorates Nonalcoholic Fatty Liver Disease in Obese, Diabetic ob/ob Mice. | 2015 | Details |
| A20305 | 26038701 | Pharmacol Res Perspect | Metformin protects primary rat hepatocytes against oxidative stress-induced apoptosis. | 2015 | Details |
| A20309 | 26035752 | Int J Mol Sci | Effect of Chronic Pioglitazone Treatment on Hepatic Gene Expression Profile in Obese C57BL/6J Mice. | 2015 | Details |
| A20312 | 26034364 | World J Gastroenterol | Cholecystectomy is independently associated with nonalcoholic fatty liver disease in an Asian population. | 2015 | Details |
| A20313 | 26033743 | J Nutr Biochem | Nutrigenomics analysis reveals that copper deficiency and dietary sucrose up-regulate inflammation, fibrosis and lipogenic pathways in a mature rat model of nonalcoholic fatty liver disease. | 2015 | Details |
| A20316 | 26032587 | Pharmacol Res | Dihydromyricetin improves glucose and lipid metabolism and exerts anti-inflammatory effects in nonalcoholic fatty liver disease: A randomized controlled trial. | 2015 | Details |
| A20320 | 26031147 | Klin Med (Mosk) | [Metabolic disorder and polymorphism of the genes encoding for beta-2-adrenergic receptor and apolipoproteins B in chronic hepatitis C and non-alcoholic fatty liver diseases]. | 2015 | Details |
| A20331 | 26026214 | Nutr Metab Cardiovasc Dis | A double-blind, placebo-controlled randomized trial to evaluate the efficacy of docosahexaenoic acid supplementation on hepatic fat and associated cardiovascular risk factors in overweight children with nonalcoholic fatty liver disease. | 2015 | Details |
| A20335 | 26024975 | Endocrine | Evidence that non-alcoholic fatty liver disease and polycystic ovary syndrome are associated by necessity rather than chance: a novel hepato-ovarian axis? | 2015 | Details |
| A20337 | 26024397 | Rocz Panstw Zakl Hig | Health effects of changes in the structure of dietary macronutrients intake in western societies. | 2015 | Details |
| A20340 | 26021772 | Saudi J Gastroenterol | The relationship of circulating fetuin-a with liver histology and biomarkers of systemic inflammation in nondiabetic subjects with nonalcoholic fatty liver disease. | 2016 | Details |
| A20345 | 26019740 | World J Hepatol | Valproic acid and nonalcoholic fatty liver disease: A possible association? | 2015 | Details |
| A20352 | 26019041 | Ann Hepatol | Combined high-fat diet and sustained high sucrose consumption promotes NAFLD in a murine model. | 2016 | Details |
| A20359 | 26017459 | Pediatr Blood Cancer | Early and progressive insulin resistance in young, non-obese cancer survivors treated with hematopoietic stem cell transplantation. | 2015 | Details |
| A20360 | 26017330 | Mol Med Rep | Lycium ruthenicum extract alleviates high-fat diet-induced nonalcoholic fatty liver disease via enhancing the AMPK signaling pathway. | 2015 | Details |
| A20364 | 26015548 | Diabetes | Growth Hormone Inhibits Hepatic De Novo Lipogenesis in Adult Mice. | 2015 | Details |
| A20367 | 26011302 | Metab Syndr Relat Disord | Insulin Resistance but Not Visceral Adiposity Index Is Associated with Liver Fibrosis in Nondiabetic Subjects with Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A20368 | 26011231 | Eur J Gastroenterol Hepatol | Increased abdominal fat levels measured by bioelectrical impedance are associated with histological lesions of nonalcoholic steatohepatitis. | 2015 | Details |
| A20370 | 26006114 | Gut | Insulin resistance alters hepatic ethanol metabolism: studies in mice and children with non-alcoholic fatty liver disease. | 2015 | Details |
| A20373 | 26005676 | Hepatobiliary Surg Nutr | Fatty liver disease in diabetes mellitus. | 2015 | Details |
| A20375 | 26004139 | Exp Gerontol | Aging impairs the hepatic subcellular distribution of ChREBP in response to fasting/feeding in rats: Implications on hepatic steatosis. | 2015 | Details |
| A20377 | 26003827 | J Endocrinol Invest | Nonalcoholic fatty liver disease and decreased bone mineral density: is there a link? | 2015 | Details |
| A20379 | 26003186 | Eur J Nutr | Moderate alcohol consumption diminishes the development of non-alcoholic fatty liver disease (NAFLD) in ob/ob mice. | 2015 | Details |
| A20386 | 25998863 | Ann N Y Acad Sci | Insulin resistance in clinical and experimental alcoholic liver disease. | 2015 | Details |
| A20389 | 25998209 | Hepatology | Phosphorylation of the nuclear receptor corepressor 1 by protein kinase B switches its corepressor targets in the liver in mice. | 2015 | Details |
| A20390 | 25997043 | Medicine (Baltimore) | A CONSORT-compliant, randomized, double-blind, placebo-controlled pilot trial of purified anthocyanin in patients with nonalcoholic fatty liver disease. | 2015 | Details |
| A20391 | 25995986 | J Diabetes Metab Disord | Diagnostic accuracy of acyl-ghrelin and it association with non-alcoholic fatty liver disease in type 2 diabetic patients. | 2015 | Details |
| A20393 | 25994073 | Diabetologia | Incretin-based therapies: where will we be 50 years from now? | 2015 | Details |
| A20397 | 25993337 | PLoS One | Ceramide as a mediator of non-alcoholic Fatty liver disease and associated atherosclerosis. | 2015 | Details |
| A20399 | 25993042 | PLoS One | Integrative genomic signatures of hepatocellular carcinoma derived from nonalcoholic Fatty liver disease. | 2015 | Details |
| A20403 | 25988570 | J Hum Nutr Diet | Associations between dietary intake and the presence of the metabolic syndrome in patients with non-alcoholic fatty liver disease. | 2015 | Details |
| A20406 | 25988358 | Atherosclerosis | Advanced fibrosis associates with atherosclerosis in subjects with nonalcoholic fatty liver disease. | 2015 | Details |
| A20410 | 25986611 | Cardiovasc Diabetol | Sex influenced association of directly measured insulin sensitivity and serum transaminase levels: Why alanine aminotransferase only predicts cardiovascular risk in men? | 2015 | Details |
| A20414 | 25982699 | Metabolism | Magnetic resonance imaging reveals altered distribution of hepatic fat in children with type 1 diabetes compared to controls. | 2015 | Details |
| A20416 | 25981325 | Diabetes Res Clin Pract | Bile acid binding resin improves hepatic insulin sensitivity by reducing cholesterol but not triglyceride levels in the liver. | 2015 | Details |
| A20424 | 25974403 | Endocrinology | 5α-Reductase Type 2 Regulates Glucocorticoid Action and Metabolic Phenotype in Human Hepatocytes. | 2015 | Details |
| A20429 | 25973422 | Biomed Res Int | The influence of metabolic factors for nonalcoholic Fatty liver disease in women. | 2015 | Details |
| A20430 | 25972092 | Biol Pharm Bull | Paeoniflorin Protects against Nonalcoholic Fatty Liver Disease Induced by a High-Fat Diet in Mice. | 2015 | Details |
| A20437 | 25966055 | Genet Mol Res | Role of APN and TNF-α in type 2 diabetes mellitus complicated by nonalcoholic fatty liver disease. | 2015 | Details |
| A20442 | 25961500 | Sci Rep | Interferon gamma-induced protein 10 is associated with insulin resistance and incident diabetes in patients with nonalcoholic fatty liver disease. | 2015 | Details |
| A20450 | 25956613 | Hepatol Int | Comparative clinical study between the effect of fenofibrate alone and its combination with pentoxifylline on biochemical parameters and liver stiffness in patients with non-alcoholic fatty liver disease. | 2015 | Details |
| A20451 | 25955209 | Cell Metab | Adaptation of hepatic mitochondrial function in humans with non-alcoholic fatty liver is lost in steatohepatitis. | 2015 | Details |
| A20457 | 25948763 | Acta Med Indones | Combination of Aspartate Aminotranferase and Tumor Necrosis Factor-α as Non Invasive Diagnostic Tools for Non Alcoholic Steatohepatitis (NASH). | 2015 | Details |
| A20458 | 25948673 | Am J Clin Nutr | Association of serum retinoic acid with hepatic steatosis and liver injury in nonalcoholic fatty liver disease. | 2015 | Details |