Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A51634 | 35467430 | Viral Immunol | Hepatitis C Virus Alters Macrophage Cholesterol Metabolism Through Interaction with Scavenger Receptors. | 2022 | Details |
| A51635 | 35466588 | Pharmacol Res Perspect | Untargeted metabolomics identifies the potential role of monocarboxylate transporter 6 (MCT6/SLC16A5) in lipid and amino acid metabolism pathways. | 2022 | Details |
| A51637 | 35453816 | Biology (Basel) | High-Fructose Diet Increases Renal ChREBPβ Expression, Leading to Intrarenal Fat Accumulation in a Rat Model with Metabolic Syndrome. | 2022 | Details |
| A51645 | 35295579 | Front Physiol | Antisense Oligonucleotide Technologies to Combat Obesity and Fatty Liver Disease. | 2022 | Details |
| A51649 | 35281936 | Front Pharmacol | Regulation of Lipid Metabolism by Lamin in Mutation-Related Diseases. | 2022 | Details |
| A51651 | 35268696 | Molecules | A Comprehensive Review on Therapeutic Perspectives of Phytosterols in Insulin Resistance: A Mechanistic Approach. | 2022 | Details |
| A51670 | 35070008 | World J Hepatol | Gut dysbiosis and systemic inflammation promote cardiomyocyte abnormalities in an experimental model of steatohepatitis. | 2021 | Details |
| A51680 | 34960775 | Viruses | High-Fat High-Sugar Diet-Induced Changes in the Lipid Metabolism Are Associated with Mildly Increased COVID-19 Severity and Delayed Recovery in the Syrian Hamster. | 2021 | Details |
| A51681 | 34959746 | Nutrients | Blueberry Counteracts Prediabetes in a Hypercaloric Diet-Induced Rat Model and Rescues Hepatic Mitochondrial Bioenergetics. | 2021 | Details |
| A51686 | 34920733 | Cardiovasc Diabetol | Pharmacometabolomic profiles in type 2 diabetic subjects treated with liraglutide or glimepiride. | 2021 | Details |
| A51692 | 34896612 | Int J Biochem Cell Biol | Odd chain fatty acid metabolism in mice after a high fat diet. | 2021 | Details |
| A51694 | 34847289 | FEBS J | Pathophysiology of type 2 diabetes and the impact of altered metabolic interorgan crosstalk. | 2021 | Details |
| A51695 | 34841293 | Cell Rep Med | Vaccine targeting ANGPTL3 ameliorates dyslipidemia and associated diseases in mouse models of obese dyslipidemia and familial hypercholesterolemia. | 2021 | Details |
| A51696 | 34836963 | Nat Commun | CRISPR-enhanced human adipocyte browning as cell therapy for metabolic disease. | 2021 | Details |
| A51699 | 34818545 | Cell Rep | The asymmetric Pitx2 gene regulates gut muscular-lacteal development and protects against fatty liver disease. | 2021 | Details |
| A51701 | 34803712 | Front Pharmacol | The Potential Application of Chinese Medicine in Liver Diseases: A New Opportunity. | 2021 | Details |
| A51706 | 34758301 | Cell Rep | The hepatic compensatory response to elevated systemic sulfide promotes diabetes. | 2021 | Details |
| A51715 | 34680405 | Biomedicines | Fat: Quality, or Quantity? What Matters Most for the Progression of Metabolic Associated Fatty Liver Disease (MAFLD). | 2021 | Details |
| A51721 | 34603196 | Front Endocrinol (Lausanne) | Serum Afamin a Novel Marker of Increased Hepatic Lipid Content. | 2021 | Details |
| A51727 | 34563954 | Biomed Pharmacother | Transcriptome analysis to reveal the mechanism of the effect of Echinops latifolius polysaccharide B on palmitate-induced insulin-resistant. | 2021 | Details |
| A51733 | 34502170 | Int J Mol Sci | Pleiotrophin Deficiency Induces Browning of Periovarian Adipose Tissue and Protects against High-Fat Diet-Induced Hepatic Steatosis. | 2021 | Details |
| A51754 | 34361064 | Int J Mol Sci | PPARs as Metabolic Sensors and Therapeutic Targets in Liver Diseases. | 2021 | Details |
| A51758 | 34322117 | Front Immunol | The Alterations in and the Role of the Th17/Treg Balance in Metabolic Diseases. | 2021 | Details |
| A51766 | 34274572 | Poult Sci | Untargeted and targeted metabolomics profiling reveals the underlying pathogenesis and abnormal arachidonic acid metabolism in laying hens with fatty liver hemorrhagic syndrome. | 2021 | Details |
| A51769 | 34264866 | JCI Insight | Prolyl-4-hydroxylase 3 maintains β cell glucose metabolism during fatty acid excess in mice. | 2021 | Details |
| A51771 | 34236076 | Clin Sci (Lond) | Glycoursodeoxycholic acid ameliorates diet-induced metabolic disorders with inhibiting endoplasmic reticulum stress. | 2021 | Details |
| A51772 | 34233623 | Cell Mol Biol Lett | Targeting the GPR119/incretin axis: a promising new therapy for metabolic-associated fatty liver disease. | 2021 | Details |
| A51776 | 34153347 | Food Chem Toxicol | Dietary nanoparticles alter the composition and function of the gut microbiota in mice at dose levels relevant for human exposure. | 2021 | Details |
| A51782 | 34116189 | J Ethnopharmacol | Danning tablets alleviate high fat diet-induced obesity and fatty liver in mice via modulating SREBP pathway. | 2021 | Details |
| A51783 | 34098336 | Environ Int | Lipid metabolism disorders associated with dioxin exposure in a cohort of Chinese male workers revealed by a comprehensive lipidomics study. | 2021 | Details |
| A51796 | 34031430 | Sci Rep | Iron supplementation regulates the progression of high fat diet induced obesity and hepatic steatosis via mitochondrial signaling pathways. | 2021 | Details |
| A51798 | 34019585 | PLoS One | FGF21 serum levels are related to insulin resistance, metabolic changes and obesity in Mexican people living with HIV (PLWH). | 2021 | Details |
| A51807 | 33962586 | Cell Mol Biol Lett | Targeting programmed cell death in metabolic dysfunction-associated fatty liver disease (MAFLD): a promising new therapy. | 2021 | Details |
| A51808 | 33962074 | Cell Mol Gastroenterol Hepatol | Sestrin Proteins Protect Against Lipotoxicity-Induced Oxidative Stress in the Liver via Suppression of C-Jun N-Terminal Kinases. | 2021 | Details |
| A51812 | 33952344 | J Anim Sci Biotechnol | Short-chain fatty acids can improve lipid and glucose metabolism independently of the pig gut microbiota. | 2021 | Details |
| A51819 | 33940322 | Int Immunopharmacol | Untargeted lipidomics analysis of Mori Fructus polysaccharide on acute alcoholic liver injury in mice using ultra performance liquid chromatography-quadrupole-orbitrap-high resolution mass spectrometry. | 2021 | Details |
| A51827 | 33894105 | Liver Int | Maternal nicotine exposure aggravates metabolic associated fatty liver disease via PI3K/Akt signaling in adult offspring mice. | 2021 | Details |
| A51831 | 33847205 | Gut Microbes | Intestinal microbiota drives cholestasis-induced specific hepatic gene expression patterns. | 2022 | Details |
| A51833 | 33833761 | Front Immunol | Hepatic Dendritic Cells in the Development and Progression of Metabolic Steatohepatitis. | 2021 | Details |
| A51837 | 33809061 | Cells | Molecular Mechanisms of Obesity-Linked Cardiac Dysfunction: An Up-Date on Current Knowledge. | 2021 | Details |
| A51838 | 33806985 | Nutrients | Soluble Fiber Inulin Consumption Limits Alterations of the Gut Microbiota and Hepatic Fatty Acid Metabolism Caused by High-Fat Diet. | 2021 | Details |
| A51841 | 33785341 | Life Sci | Vascular endothelial growth factor B exerts lipid-lowering effect by activating AMPK via VEGFR1. | 2021 | Details |
| A51848 | 33746902 | Front Endocrinol (Lausanne) | The Impact of Gut Microbiome on Metabolic Disorders During Catch-Up Growth in Small-for-Gestational-Age. | 2021 | Details |
| A51850 | 33687947 | Cancer Res | Fat Induces Glucose Metabolism in Nontransformed Liver Cells and Promotes Liver Tumorigenesis. | 2021 | Details |
| A51858 | 33633583 | Front Physiol | Serum Metabolomic Profiling to Reveal Potential Biomarkers for the Diagnosis of Fatty Liver Hemorrhagic Syndrome in Laying Hens. | 2021 | Details |
| A51874 | 33535680 | Int J Mol Sci | Effects of Pyrroloquinoline Quinone on Lipid Metabolism and Anti-Oxidative Capacity in a High-Fat-Diet Metabolic Dysfunction-Associated Fatty Liver Disease Chick Model. | 2021 | Details |
| A51882 | 33485967 | J Biol Chem | Changes in retinoid metabolism and signaling associated with metabolic remodeling during fasting and in type I diabetes. | 2021 | Details |
| A51886 | 33455774 | J Dairy Sci | Relationships between metabolic profiles and gene expression in liver and leukocytes of dairy cows in early lactation. | 2021 | Details |
| A51888 | 33449293 | Endocrine | Glucocorticoid signaling and lipid metabolism disturbances in the liver of rats treated with 5α-dihydrotestosterone in an animal model of polycystic ovary syndrome. | 2021 | Details |
| A51901 | 33347566 | J Clin Endocrinol Metab | Plasma Bile Acids More Closely Align With Insulin Resistance, Visceral and Hepatic Adiposity Than Total Adiposity. | 2021 | Details |
| A51902 | 33340617 | Cancer Lett | ACSL4 reprograms fatty acid metabolism in hepatocellular carcinoma via c-Myc/SREBP1 pathway. | 2020 | Details |
| A51907 | 33304629 | Curr Health Sci J | Facing the Unseen - Metabolic Syndrome in Psoriatic Arthritis. | 2020 | Details |
| A51908 | 33303358 | Neuromuscul Disord | Early onset neutral lipid storage disease with myopathy presenting as congenital hypotonia and hepatomegaly. | 2020 | Details |
| A51912 | 33292312 | Nutr Metab (Lond) | Tandem Mass Tag-based quantitative proteomics analysis of metabolic associated fatty liver disease induced by high fat diet in mice. | 2020 | Details |
| A51913 | 33291840 | Animals (Basel) | Administration of Protein Hydrolysates from Anchovy (Engraulis Encrasicolus) Waste for Twelve Weeks Decreases Metabolic Dysfunction-Associated Fatty Liver Disease Severity in ApoE-/-Mice. | 2020 | Details |
| A51914 | 33273564 | Sci Rep | Short-term Cudrania tricuspidata fruit vinegar administration attenuates obesity in high-fat diet-fed mice by improving fat accumulation and metabolic parameters. | 2020 | Details |
| A51915 | 33273482 | Sci Rep | NLRP3 inflammasome deficiency attenuates metabolic disturbances involving alterations in the gut microbial profile in mice exposed to high fat diet. | 2020 | Details |
| A51916 | 33264641 | Cancer Lett | FGF21 in obesity and cancer: New insights. | 2020 | Details |
| A51919 | 33244184 | Commun Biol | Cerebellar and hepatic alterations in ACBD5-deficient mice are associated with unexpected, distinct alterations in cellular lipid homeostasis. | 2020 | Details |
| A51920 | 33233602 | Int J Mol Sci | Lipodystrophies-Disorders of the Fatty Tissue. | 2020 | Details |
| A51922 | 33228176 | Nutrients | Effects of β-glucan Rich Barley Flour on Glucose and Lipid Metabolism in the Ileum, Liver, and Adipose Tissues of High-Fat Diet Induced-Obesity Model Male Mice Analyzed by DNA Microarray. | 2020 | Details |
| A51924 | 33189279 | J Dairy Sci | Differential gene expression in dairy cows under negative energy balance and ketosis: A systematic review and meta-analysis. | 2020 | Details |
| A51926 | 33170807 | JCI Insight | Depletion of protein kinase STK25 ameliorates renal lipotoxicity and protects against diabetic kidney disease. | 2020 | Details |
| A51928 | 33168096 | Hum Genomics | Aldh1l2 knockout mouse metabolomics links the loss of the mitochondrial folate enzyme to deregulation of a lipid metabolism observed in rare human disorder. | 2020 | Details |
| A51938 | 33076503 | Cells | Metabolism-Disrupting Chemicals and the Constitutive Androstane Receptor CAR. | 2020 | Details |
| A51942 | 33038868 | Phytomedicine | Suppression of up-regulated LXRα by silybin ameliorates experimental rheumatoid arthritis and abnormal lipid metabolism. | 2020 | Details |
| A51969 | 32811819 | Nat Commun | Age-dependent loss of adipose Rubicon promotes metabolic disorders via excess autophagy. | 2020 | Details |
| A51971 | 32726932 | Nutrients | Adaptive Fat Oxidation Is Coupled with Increased Lipid Storage in Adipose Tissue of Female Mice Fed High Dietary Fat and Sucrose. | 2020 | Details |
| A51972 | 32719086 | Drug Metab Dispos | Multiomics Profiling Reveals Protective Function of Schisandra Lignans against Acetaminophen-Induced Hepatotoxicity. | 2020 | Details |
| A51973 | 32712422 | Environ Int | Serum metabolic changes associated with dioxin exposure in a Chinese male cohort. | 2020 | Details |
| A51976 | 32691632 | Am J Physiol Endocrinol Metab | Hydroxysteroid (17β) dehydrogenase 12 is essential for metabolic homeostasis in adult mice. | 2020 | Details |
| A51978 | 32663609 | Biochim Biophys Acta Mol Cell Biol Lipids | Neurotensin up-regulation is associated with advanced fibrosis and hepatocellular carcinoma in patients with MAFLD. | 2020 | Details |
| A51987 | 32595984 | Cell Death Discov | The role of MDM2-p53 axis dysfunction in the hepatocellular carcinoma transformation. | 2020 | Details |
| A52000 | 32483465 | Theranostics | STIM1 is a metabolic checkpoint regulating the invasion and metastasis of hepatocellular carcinoma. | 2020 | Details |
| A52015 | 32290082 | Int J Mol Sci | Lipotoxicity and Diabetic Nephropathy: Novel Mechanistic Insights and Therapeutic Opportunities. | 2020 | Details |
| A52023 | 32200644 | Am J Physiol Gastrointest Liver Physiol | Fermentable fibers induce rapid macro- and micronutrient depletion in Toll-like receptor 5-deficient mice. | 2020 | Details |
| A52024 | 32198195 | Diabetes | Exercise Combats Hepatic Steatosis: Potential Mechanisms and Clinical Implications. | 2020 | Details |
| A52029 | 32151973 | iScience | FAM13A Represses AMPK Activity and Regulates Hepatic Glucose and Lipid Metabolism. | 2020 | Details |
| A52037 | 32039990 | Curr Opin Lipidol | Hypobetalipoproteinemia and abetalipoproteinemia: liver disease and cardiovascular disease. | 2020 | Details |
| A52040 | 31988048 | Biochim Biophys Acta Mol Cell Biol Lipids | Dysregulation of microRNA-125a contributes to obesity-associated insulin resistance and dysregulates lipid metabolism in mice. | 2020 | Details |
| A52043 | 31944172 | Autophagy | Metabolic effects of RUBCN/Rubicon deficiency in kidney proximal tubular epithelial cells. | 2020 | Details |
| A52045 | 31925559 | Metabolomics | Anabolic androgenic steroids exert a selective remodeling of the plasma lipidome that mirrors the decrease of the de novo lipogenesis in the liver. | 2020 | Details |
| A52049 | 31900483 | Endocrinology | CPT1A-mediated Fat Oxidation, Mechanisms, and Therapeutic Potential. | 2020 | Details |
| A52051 | 31888144 | Int J Mol Sci | Altered Metabolic Profile and Adipocyte Insulin Resistance Mark Severe Liver Fibrosis in Patients with Chronic Liver Disease. | 2019 | Details |
| A52056 | 31822562 | J Biol Chem | Distinct alterations of gut morphology and microbiota characterize accelerated diabetes onset in nonobese diabetic mice. | 2019 | Details |
| A52058 | 31786232 | Biochimie | Vegetable lecithins: A review of their compositional diversity, impact on lipid metabolism and potential in cardiometabolic disease prevention. | 2019 | Details |
| A52062 | 31743877 | Biomed Pharmacother | An integrated fecal microbiome and metabolome in the aged mice reveal anti-aging effects from the intestines and biochemical mechanism of FuFang zhenshu TiaoZhi(FTZ). | 2019 | Details |
| A52070 | 31676443 | Biochim Biophys Acta Mol Cell Biol Lipids | Increased fatty acid oxidation and mitochondrial proliferation in liver are associated with increased plasma kynurenine metabolites and nicotinamide levels in normolipidemic and carnitine-depleted rats. | 2019 | Details |
| A52071 | 31676441 | Biochim Biophys Acta Mol Cell Biol Lipids | PPARA/RXRA signalling regulates the fate of hepatic non-esterified fatty acids in a sheep model of maternal undernutrition. | 2019 | Details |
| A52072 | 31672551 | Biochim Biophys Acta Mol Basis Dis | Fasting reveals largely intact systemic lipid mobilization mechanisms in respiratory chain complex III deficient mice. | 2019 | Details |
| A52077 | 31601915 | Sci Rep | Dysregulated liver lipid metabolism and innate immunity associated with hepatic steatosis in neonatal BBdp rats and NOD mice. | 2019 | Details |
| A52078 | 31592400 | Diabetol Int | Drug development research for novel adiponectin receptor-targeted antidiabetic drugs contributing to healthy longevity. | 2019 | Details |
| A52080 | 31573846 | Am J Physiol Endocrinol Metab | The antagonist of CXCR1 and CXCR2 protects db/db mice from metabolic diseases through modulating inflammation. | 2019 | Details |
| A52081 | 31565213 | Ther Adv Endocrinol Metab | Update on the synergistic effect of HSL and insulin in the treatment of metabolic disorders. | 2019 | Details |
| A52092 | 31340878 | Proc Nutr Soc | Different physiological mechanisms underlie an adverse cardiovascular disease risk profile in men and women. | 2019 | Details |
| A52095 | 31308847 | PPAR Res | Short-Term Activation of Peroxisome Proliferator-Activated Receptors α and γ Induces Tissue-Specific Effects on Lipid Metabolism and Fatty Acid Composition in Male Wistar Rats. | 2019 | Details |
| A52096 | 31307210 | FASEB J | Ileal interposition surgery targets the hepatic TGF-β pathway, influencing gluconeogenesis and mitochondrial bioenergetics in the UCD-T2DM rat model of diabetes. | 2019 | Details |
| A52098 | 31281982 | Lipids | Adipocyte Fatty Acid-Binding Protein as a Novel Marker of Psoriasis and Clinical Response to Acitretin. | 2019 | Details |
| A52100 | 31257031 | Cell | Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner. | 2019 | Details |
| A52101 | 31243135 | J Virol | Transforming Growth Factor β Acts as a Regulatory Molecule for Lipogenic Pathways among Hepatitis C Virus Genotype-Specific Infections. | 2019 | Details |