Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A33696 | 25385666 | Ir J Med Sci | Liver injury attenuation by curcumin in a rat NASH model: an Nrf2 activation-mediated effect? | 2014 | Details |
| A33719 | 25314080 | Cancer Cell | Metabolic activation of intrahepatic CD8+ T cells and NKT cells causes nonalcoholic steatohepatitis and liver cancer via cross-talk with hepatocytes. | 2014 | Details |
| A33735 | 25279794 | Endocrinology | Osteocalcin protects against nonalcoholic steatohepatitis in a mouse model of metabolic syndrome. | 2014 | Details |
| A33760 | 25202950 | Zhong Nan Da Xue Xue Bao Yi Xue Ban | [Effect of free fatty acid on NALP3 inflammasome signaling pathway in THP-1 macrophages]. | 2014 | Details |
| A33779 | 25169677 | Neurobiol Aging | Activated human microglia stimulate neuroblastoma cells to upregulate production of beta amyloid protein and tau: implications for Alzheimer's disease pathogenesis. | 2014 | Details |
| A33799 | 25132496 | Cancer Cell | ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development. | 2014 | Details |
| A33828 | 25066692 | Gastroenterology | Roles for chemokines in liver disease. | 2014 | Details |
| A33839 | 25038800 | BMC Complement Altern Med | Anti-lipoapoptotic effect of Artemisia capillaris extract on free fatty acids-induced HepG2 cells. | 2014 | Details |
| A33844 | 25036371 | J Neurotrauma | Spinal cord injury causes chronic liver pathology in rats. | 2014 | Details |
| A33915 | 24885871 | Lipids Health Dis | Linoleate appears to protect against palmitate-induced inflammation in Huh7 cells. | 2014 | Details |
| A33927 | 24842243 | Diabetes Res Clin Pract | Sitagliptin attenuates methionine/choline-deficient diet-induced steatohepatitis. | 2014 | Details |
| A33932 | 24831018 | Osteoarthritis Cartilage | Effect of hydrogen sulfide sources on inflammation and catabolic markers on interleukin 1β-stimulated human articular chondrocytes. | 2014 | Details |
| A33941 | 24813992 | Biochem Biophys Res Commun | Therapeutic potential of flurbiprofen against obesity in mice. | 2014 | Details |
| A33948 | 24795769 | Evid Based Complement Alternat Med | Effects of Chaihu-Shugan-San and Shen-Ling-Bai-Zhu-San on p38 MAPK Pathway in Kupffer Cells of Nonalcoholic Steatohepatitis. | 2014 | Details |
| A33966 | 24763197 | Exp Mol Med | Oleuropein prevents the progression of steatohepatitis to hepatic fibrosis induced by a high-fat diet in mice. | 2014 | Details |
| A34024 | 24604589 | Ann Surg Oncol | Neoadjuvant radiation therapy prior to total mesorectal excision for rectal cancer is not associated with postoperative complications using current techniques. | 2014 | Details |
| A34035 | 24582082 | Dig Liver Dis | Lack of interleukin-1α in Kupffer cells attenuates liver inflammation and expression of inflammatory cytokines in hypercholesterolaemic mice. | 2014 | Details |
| A34076 | 24471744 | J Pharm Pharmacol | Bupropion effects on high-fat diet-induced steatohepatitis and endothelial dysfunction in rats: role of tumour necrosis factor-alpha. | 2014 | Details |
| A34109 | 27433515 | Int Sch Res Notices | Serological and Histological Examination of a Nonalcoholic Steatohepatitis Mouse Model Created via the Administration of Monosodium Glutamate. | 2014 | Details |
| A34126 | 26858881 | Cell Med | Experimental Nonalcoholic Steatohepatitis Induced by Neonatal Streptozotocin Injection and a High-Fat Diet in Rats. | 2013 | Details |
| A34150 | 24312444 | PLoS One | Macrophage specific caspase-1/11 deficiency protects against cholesterol crystallization and hepatic inflammation in hyperlipidemic mice. | 2013 | Details |
| A34197 | 24156694 | J Toxicol Environ Health A | Oxidative stress, inflammatory biomarkers, and toxicity in mouse lung and liver after inhalation exposure to 100% biodiesel or petroleum diesel emissions. | 2013 | Details |
| A34216 | 24067460 | Int J Immunopathol Pharmacol | Sulphurous thermal water increases the release of the anti-inflammatory cytokine IL-10 and modulates antioxidant enzyme activity. | 2014 | Details |
| A34237 | 23996730 | Hepatology | Transforming growth factor beta signaling in hepatocytes participates in steatohepatitis through regulation of cell death and lipid metabolism in mice. | 2013 | Details |
| A34250 | 23968887 | J Hepatol | CD141⁺ myeloid dendritic cells are enriched in healthy human liver. | 2013 | Details |
| A34278 | 23877747 | Nutr Diabetes | Lycium barbarum polysaccharides protect rat liver from non-alcoholic steatohepatitis-induced injury. | 2013 | Details |
| A34283 | 23866683 | J Neuroinflammation | Diverse activation of microglia by chemokine (C-C motif) ligand 2 overexpression in brain. | 2013 | Details |
| A34296 | 23828575 | Cell Death Dis | Diabetic liver injury from streptozotocin is regulated through the caspase-8 homolog cFLIP involving activation of JNK2 and intrahepatic immunocompetent cells. | 2013 | Details |
| A34361 | 23640861 | Toxicol Sci | Environmental toxin-linked nonalcoholic steatohepatitis and hepatic metabolic reprogramming in obese mice. | 2013 | Details |
| A34373 | 23617943 | Liver Int | Trapping of oxidized LDL in lysosomes of Kupffer cells is a trigger for hepatic inflammation. | 2013 | Details |
| A34410 | 23526264 | J Clin Biochem Nutr | Effects of tocotrienol on tumor necrosis factor-α/d-galactosamine-induced steatohepatitis in rats. | 2013 | Details |
| A34453 | 23409132 | PLoS One | Caspase-1 as a central regulator of high fat diet-induced non-alcoholic steatohepatitis. | 2013 | Details |
| A34455 | 23402745 | J Hepatol | Activated intestinal macrophages in patients with cirrhosis release NO and IL-6 that may disrupt intestinal barrier function. | 2013 | Details |
| A34486 | 23339067 | Hepatology | Hepatocyte caspase-8 is an essential modulator of steatohepatitis in rodents. | 2013 | Details |
| A34499 | 23322710 | Hepatology | Dendritic cells limit fibroinflammatory injury in nonalcoholic steatohepatitis in mice. | 2013 | Details |
| A34509 | 23281043 | Hepatology | Brahma-related gene 1 bridges epigenetic regulation of proinflammatory cytokine production to steatohepatitis in mice. | 2013 | Details |
| A34532 | 24695939 | Hepat Med | Treatment of nonalcoholic steatohepatitis with vitamins E and C: a pilot study. | 2013 | Details |
| A34545 | 23233000 | Surg Endosc | Resistin expression correlates with steatohepatitis in morbidly obese patients. | 2012 | Details |
| A34575 | 23170052 | J Clin Biochem Nutr | Anti-oxidative and anti-inflammatory effects of spirulina on rat model of non-alcoholic steatohepatitis. | 2012 | Details |
| A34581 | 23149694 | Genes Nutr | Time-dependent network analysis reveals molecular targets underlying the development of diet-induced obesity and non-alcoholic steatohepatitis. | 2012 | Details |
| A34608 | 23071503 | PLoS One | Type III interferons, IL-28 and IL-29, are increased in chronic HCV infection and induce myeloid dendritic cell-mediated FoxP3+ regulatory T cells. | 2012 | Details |
| A34662 | 22971151 | Hepatol Res | Pitavastatin ameliorated the progression of steatohepatitis in ovariectomized mice fed a high fat and high cholesterol diet. | 2012 | Details |
| A34680 | 22918204 | Acta Med Okayama | Water extract of Vitis coignetiae Pulliat leaves attenuates oxidative stress and inflammation in progressive NASH rats. | 2012 | Details |
| A34685 | 22882855 | Chin Med J (Engl) | Pioglitazone ameliorates nonalcoholic steatohepatitis by down-regulating hepatic nuclear factor-kappa B and cyclooxygenases-2 expression in rats. | 2012 | Details |
| A34789 | 22592920 | Am J Respir Cell Mol Biol | Hydrogen sulfide attenuates particulate matter-induced human lung endothelial barrier disruption via combined reactive oxygen species scavenging and Akt activation. | 2012 | Details |
| A34824 | 22515414 | Nutr Metab (Lond) | Docosahexaenoic acid ameliorates palmitate-induced lipid accumulation and inflammation through repressing NLRC4 inflammasome activation in HepG2 cells. | 2012 | Details |
| A34846 | 22442158 | Am J Physiol Gastrointest Liver Physiol | Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2. | 2012 | Details |
| A34854 | 22425700 | J Hepatol | FOXP3+ regulatory T cells in autoimmune hepatitis are fully functional and not reduced in frequency. | 2012 | Details |
| A34859 | 22411067 | Lab Invest | Caspase-1-mediated regulation of fibrogenesis in diet-induced steatohepatitis. | 2012 | Details |
| A34866 | 22392635 | Hepatology | Inhibition of natural killer cells protects the liver against acute injury in the absence of glycine N-methyltransferase. | 2012 | Details |
| A34900 | 22245892 | J Hepatol | Structural and inflammatory heterogeneity in subcutaneous adipose tissue: relation with liver histopathology in morbid obesity. | 2012 | Details |
| A34967 | 22110414 | Case Rep Gastroenterol | Histological Remission during Corticosteroid Therapy of Overlapping Nonalcoholic Steatohepatitis and Autoimmune Hepatitis: Case Report and Literature Review. | 2011 | Details |
| A35022 | 21933146 | Curr Pharm Des | Metabolic therapy: lessons from liver diseases. | 2011 | Details |
| A35059 | 21845516 | J Clin Immunol | Altered phenotype and functionality of circulating immune cells characterize adult patients with nonalcoholic steatohepatitis. | 2011 | Details |
| A35107 | 21715691 | J Immunol | Prostaglandin D2 regulates CD4+ memory T cell trafficking across blood vascular endothelium and primes these cells for clearance across lymphatic endothelium. | 2011 | Details |
| A35113 | 21711424 | Hepatol Res | Ursodeoxycholic acid dose-dependently improves liver injury in rats fed a methionine- and choline-deficient diet. | 2011 | Details |
| A35214 | 21425308 | Hepatology | Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice. | 2011 | Details |
| A35224 | 21376711 | Chem Biol Interact | Cytotoxic molecular mechanisms and cytoprotection by enzymic metabolism or autoxidation for glyceraldehyde, hydroxypyruvate and glycolaldehyde. | 2011 | Details |
| A35227 | 21373270 | J Clin Biochem Nutr | Bach1 gene ablation reduces steatohepatitis in mouse MCD diet model. | 2010 | Details |
| A35236 | 21338455 | Hepatol Res | Late diagnosed Wilson disease with hepatic and neurological manifestations. | 2011 | Details |
| A35237 | 21338452 | Hepatol Res | Pharmacological therapy of nonalcoholic steatohepatitis. | 2011 | Details |
| A35238 | 21335007 | Gastroenterology | Iron levels in hepatocytes and portal tract cells predict progression and outcomes of patients with advanced chronic hepatitis C. | 2011 | Details |
| A35249 | 21299162 | Acta Gastroenterol Belg | Why should the gastroenterologist bother about obesity? An oncologic point of view. | 2011 | Details |
| A35259 | 21276150 | Hepatol Res | Pitavastatin inhibits hepatic steatosis and fibrosis in non-alcoholic steatohepatitis model rats. | 2011 | Details |
| A35307 | 21146362 | Int J Oral Maxillofac Surg | Non-alcoholic steatohepatitis (NASH) and oral lichen planus: a rare occurrence. | 2010 | Details |
| A35325 | 21081801 | J Physiol Pharmacol | The effects of L-tryptophan and melatonin on selected biochemical parameters in patients with steatohepatitis. | 2010 | Details |
| A35338 | 21056947 | Hum Exp Toxicol | Teucrium polium reversed the MCD diet-induced liver injury in rats. | 2010 | Details |
| A35342 | 21046243 | Dig Dis Sci | Small intestinal bacterial overgrowth in nonalcoholic steatohepatitis: association with toll-like receptor 4 expression and plasma levels of interleukin 8. | 2010 | Details |
| A35412 | 20810317 | Curr Opin Pharmacol | Mechanisms of adiponectin regulation and use as a pharmacological target. | 2010 | Details |
| A35430 | 20707200 | Zhongguo Zhong Yao Za Zhi | [Cigu Xiaozhi pills's influence on lipid peroxidation and TNF-alpha expression in liver tissues of rats with nonalcoholic steatohepatitis]. | 2010 | Details |
| A35445 | 20660987 | Exp Anim | Insulin resistance, steatohepatitis, and hepatocellular carcinoma in a new congenic strain of Fatty Liver Shionogi (FLS) mice with the Lep(ob) gene. | 2010 | Details |
| A35453 | 20625232 | J Oleo Sci | Effects of docosahexaenoic acid in an experimental rat model of nonalcoholic steatohepatitis. | 2010 | Details |
| A35462 | 20606728 | Int J Clin Exp Pathol | Regulation of oxidative stress and inflammation by hepatic adiponectin receptor 2 in an animal model of nonalcoholic steatohepatitis. | 2010 | Details |
| A35464 | 20596733 | J Gastroenterol | Absence of invariant natural killer T cells deteriorates liver inflammation and fibrosis in mice fed high-fat diet. | 2010 | Details |
| A35509 | 20489159 | Am J Pathol | A human-type nonalcoholic steatohepatitis model with advanced fibrosis in rabbits. | 2010 | Details |
| A35520 | 20454933 | Obes Surg | Pro- and anti-inflammatory cytokines in steatosis and steatohepatitis. | 2010 | Details |
| A35529 | 21949477 | Hepat Med | Mice with null mutation of Ceacam I develop nonalcoholic steatohepatitis. | 2010 | Details |
| A35552 | 20376096 | Gene Ther | PPARgamma is essential for protection against nonalcoholic steatohepatitis. | 2010 | Details |
| A35557 | 20368703 | Lab Invest | Blockade of interleukin-6 signaling enhances hepatic steatosis but improves liver injury in methionine choline-deficient diet-fed mice. | 2010 | Details |
| A35566 | 20353017 | Zhongguo Zhong Yao Za Zhi | [Effect of total flavones of hawthorn leafon (TFHL) on expression of UCP2 in liver of NASH rats]. | 2009 | Details |
| A35570 | 20347818 | Gastroenterology | Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice. | 2010 | Details |
| A35593 | 20206177 | Gastroenterology | Role of scavenger receptor A and CD36 in diet-induced nonalcoholic steatohepatitis in hyperlipidemic mice. | 2010 | Details |
| A35630 | 20068559 | Am J Gastroenterol | L-carnitine supplementation to diet: a new tool in treatment of nonalcoholic steatohepatitis--a randomized and controlled clinical trial. | 2010 | Details |
| A35639 | 21483580 | Libyan J Med | A preliminary study of inflammatory markers in non-alcoholic steatohepatitis patients. | 2010 | Details |
| A35640 | 20041267 | Surg Endosc | Adiponectin but not leptin is involved in early hepatic disease in morbidly obese patients. | 2009 | Details |
| A35649 | 20028520 | Pediatr Rheumatol Online J | Acute hepatitis in three patients with systemic juvenile idiopathic arthritis taking interleukin-1 receptor antagonist. | 2009 | Details |
| A35650 | 20028348 | Alcohol Clin Exp Res | Moderate alcohol consumption aggravates high-fat diet induced steatohepatitis in rats. | 2009 | Details |
| A35692 | 19902480 | Hepatology | Toxicant-associated steatohepatitis in vinyl chloride workers. | 2010 | Details |
| A35728 | 19824078 | Hepatology | Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial. | 2009 | Details |
| A35744 | 19785957 | Zhonghua Gan Zang Bing Za Zhi | [Role of resistin in inflammation of hepatocytes in nonalcoholic steatohepatitis]. | 2009 | Details |
| A35753 | 19764881 | Antioxid Redox Signal | Thioredoxin-binding protein-2 deficiency enhances methionine-choline deficient diet-induced hepatic steatosis but inhibits steatohepatitis in mice. | 2009 | Details |
| A35765 | 19748164 | Clin Nutr | Inhibition of JNK along with activation of ERK1/2 MAPK pathways improve steatohepatitis among the rats. | 2009 | Details |
| A35770 | 19729473 | Am J Pathol | Increased hepatic myeloperoxidase activity in obese subjects with nonalcoholic steatohepatitis. | 2009 | Details |
| A35772 | 19721198 | Clin Calcium | [Hepato-biliary and pancreatic disease and osteodystrophy]. | 2009 | Details |
| A35781 | 19707265 | PLoS Biol | Omega-3 Fatty acids and inflammation: novel interactions reveal a new step in neutrophil recruitment. | 2009 | Details |
| A35815 | 19631409 | Neurobiol Aging | Astrocytes produce the antiinflammatory and neuroprotective agent hydrogen sulfide. | 2009 | Details |
| A35822 | 19606393 | Scand J Gastroenterol | Antioxidants vitamin E and 1-aminobenzotriazole prevent experimental non-alcoholic steatohepatitis in mice. | 2009 | Details |
| A35856 | 19552763 | J Pineal Res | Melatonin ameliorates methionine- and choline-deficient diet-induced nonalcoholic steatohepatitis in rats. | 2009 | Details |
| A35858 | 19551842 | Int J Cancer | Dietary lycopene and tomato extract supplementations inhibit nonalcoholic steatohepatitis-promoted hepatocarcinogenesis in rats. | 2010 | Details |
| A35862 | 19544392 | Glia | Hydrogen sulfide-releasing NSAIDs attenuate neuroinflammation induced by microglial and astrocytic activation. | 2010 | Details |