Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A52102 | 31215667 | Ann N Y Acad Sci | The pan-cancer mutational landscape of the PPAR pathway reveals universal patterns of dysregulated metabolism and interactions with tumor immunity and hypoxia. | 2019 | Details |
| A52104 | 31184331 | Rev Invest Clin | NUTRIGENOMICS AS A TOOL IN THE PREVENTION OF LIPOTOXICITY: THE CASE OF SOY PROTEIN. | 2019 | Details |
| A52107 | 31121167 | Gastroenterology | Liver Fibrosis and Metabolic Alterations in Adults With alpha-1-antitrypsin Deficiency Caused by the Pi*ZZ Mutation. | 2019 | Details |
| A52112 | 31088359 | BMC Genomics | Transcriptomic analysis between Normal and high-intake feeding geese provides insight into adipose deposition and susceptibility to fatty liver in migratory birds. | 2019 | Details |
| A52117 | 31012326 | Am J Chin Med | Metabonomics Study on the Hepatoprotective Effect of Panax notoginseng Leaf Saponins Using UPLC/Q-TOF-MS Analysis. | 2019 | Details |
| A52119 | 31003793 | Int J Cardiol | Right ventricular pressure overload alters cardiac lipid composition. | 2019 | Details |
| A52121 | 30979946 | Sci Rep | Early impairments in the retina of rats fed with high fructose/high fat diet are associated with glucose metabolism deregulation but not dyslipidaemia. | 2019 | Details |
| A52126 | 30954078 | Lipids Health Dis | Perilipin 5 alleviates HCV NS5A-induced lipotoxic injuries in liver. | 2019 | Details |
| A52128 | 30936147 | Diabetes | Altered In Vivo Lipid Fluxes and Cell Dynamics in Subcutaneous Adipose Tissues Are Associated With the Unfavorable Pattern of Fat Distribution in Obese Adolescent Girls. | 2019 | Details |
| A52129 | 30936145 | Diabetes | Hepatocyte-Specific Ablation or Whole-Body Inhibition of Xanthine Oxidoreductase in Mice Corrects Obesity-Induced Systemic Hyperuricemia Without Improving Metabolic Abnormalities. | 2019 | Details |
| A52130 | 30921498 | Mol Nutr Food Res | Dietary Palmitoleic Acid Attenuates Atherosclerosis Progression and Hyperlipidemia in Low-Density Lipoprotein Receptor-Deficient Mice. | 2019 | Details |
| A52131 | 30920846 | Am J Physiol Gastrointest Liver Physiol | Intestinal serine protease inhibition increases FGF21 and improves metabolism in obese mice. | 2019 | Details |
| A52132 | 30903919 | Biomed Pharmacother | Chinese medicine Jinlida granules improve high-fat-diet induced metabolic disorders via activation of brown adipose tissue in mice. | 2019 | Details |
| A52135 | 30858281 | EMBO J | Cideb controls sterol-regulated ER export of SREBP/SCAP by promoting cargo loading at ER exit sites. | 2019 | Details |
| A52140 | 30796305 | Sci Rep | Reduced hepatocellular lipid accumulation and energy metabolism in patients with long standing type 1 diabetes mellitus. | 2019 | Details |
| A52143 | 30733237 | Dis Model Mech | Differential regulation of the unfolded protein response in outbred deer mice and susceptibility to metabolic disease. | 2019 | Details |
| A52144 | 30723473 | Front Immunol | Spred2 Regulates High Fat Diet-Induced Adipose Tissue Inflammation, and Metabolic Abnormalities in Mice. | 2019 | Details |
| A52147 | 30684909 | Res Vet Sci | Protein and gene expression of relevant enzymes and nuclear receptor of hepatic lipid metabolism in grazing dairy cattle during the transition period. | 2019 | Details |
| A52148 | 30679938 | Nutr Metab (Lond) | Dietary supplement of Smilax china L. ethanol extract alleviates the lipid accumulation by activating AMPK pathways in high-fat diet fed mice. | 2019 | Details |
| A52149 | 30665623 | Trends Pharmacol Sci | Lysosomal Acid Lipase: From Cellular Lipid Handler to Immunometabolic Target. | 2019 | Details |
| A52150 | 30664268 | Hepatology | E-cigarettes and Western Diet: Important Metabolic Risk Factors for Hepatic Diseases. | 2019 | Details |
| A52157 | 30585632 | J Cell Physiol | The underlying pathophysiology association between the Type 2-diabetic and hepatocellular carcinoma. | 2018 | Details |
| A52158 | 30574122 | Front Endocrinol (Lausanne) | Sirtuins and Insulin Resistance. | 2018 | Details |
| A52160 | 30563203 | Int J Mol Sci | Dysregulation of Lipid Metabolism in Mkp-1 Deficient Mice during Gram-Negative Sepsis. | 2018 | Details |
| A52162 | 30551378 | Biomed Pharmacother | A novel recombinant peptide INSR-IgG4Fc (Yiminsu) restores insulin sensitivity in experimental insulin resistance models. | 2018 | Details |
| A52164 | 30520016 | Int J Cancer | Impact of systemic and tumor lipid metabolism on everolimus efficacy in advanced pancreatic neuroendocrine tumors (pNETs). | 2019 | Details |
| A52166 | 30481177 | PLoS One | A metabolome-wide characterization of the diabetic phenotype in ZDF rats and its reversal by pioglitazone. | 2018 | Details |
| A52168 | 30474622 | Med Sci Monit | The Adenosine Monophosphate (AMP) Analog, 5-Aminoimidazole-4-Carboxamide Ribonucleotide (AICAR) Inhibits Hepatosteatosis and Liver Tumorigenesis in a High-Fat Diet Murine Model Treated with Diethylnitrosamine (DEN). | 2018 | Details |
| A52169 | 30465787 | Toxicol Appl Pharmacol | Clozapine-induced reduction of l-carnitine reabsorption via inhibition/down-regulation of renal carnitine/organic cation transporter 2 contributes to liver lipid metabolic disorder in mice. | 2018 | Details |
| A52171 | 30463291 | Nutrients | Ishige okamurae Extract Suppresses Obesity and Hepatic Steatosis in High Fat Diet-Induced Obese Mice. | 2018 | Details |
| A52172 | 30429322 | Proc Natl Acad Sci U S A | Obesity-associated exosomal miRNAs modulate glucose and lipid metabolism in mice. | 2018 | Details |
| A52174 | 30423963 | Nutrients | Ursolic Acid Attenuates Hepatic Steatosis, Fibrosis, and Insulin Resistance by Modulating the Circadian Rhythm Pathway in Diet-Induced Obese Mice. | 2018 | Details |
| A52183 | 30345810 | Avian Pathol | Fatty liver haemorrhagic syndrome occurrence in laying hens: impact of production system. | 2018 | Details |
| A52187 | 30308265 | Mol Cell Endocrinol | A short periconceptional exposure to maternal type-1 diabetes is sufficient to disrupt the feto-placental phenotype in a rabbit model. | 2018 | Details |
| A52204 | 30133327 | FASEB J | Chronic psychosocial defeat differently affects lipid metabolism in liver and white adipose tissue and induces hepatic oxidative stress in mice fed a high-fat diet. | 2018 | Details |
| A52207 | 30117411 | Animal | Molecular mechanisms of lipid metabolism disorder in livers of ewes with pregnancy toxemia. | 2018 | Details |
| A52212 | 30060615 | Mar Drugs | Functional Comparison of High and Low Molecular Weight Chitosan on Lipid Metabolism and Signals in High-Fat Diet-Fed Rats. | 2018 | Details |
| A52213 | 30049588 | Nutr Res | The interplay of canonical and noncanonical Wnt signaling in metabolic syndrome. | 2018 | Details |
| A52219 | 29980484 | Mol Metab | FGF21 regulates insulin sensitivity following long-term chronic stress. | 2018 | Details |
| A52222 | 29942089 | Nat Med | Genetic deficiency of indoleamine 2,3-dioxygenase promotes gut microbiota-mediated metabolic health. | 2018 | Details |
| A52225 | 29931052 | Cardiovasc Res | Heart specific PGC-1α deletion identifies metabolome of cardiac restricted metabolic heart failure. | 2019 | Details |
| A52236 | 29873499 | J Proteome Res | Metabolic Profiling of Multiorgan Samples: Evaluation of MODY5/RCAD Mutant Mice. | 2018 | Details |
| A52237 | 29872321 | Onco Targets Ther | Downregulation of CPT2 promotes tumorigenesis and chemoresistance to cisplatin in hepatocellular carcinoma. | 2018 | Details |
| A52242 | 29786646 | Int J Mol Sci | Metabolic Reprogramming by 3-Iodothyronamine (T1AM): A New Perspective to Reverse Obesity through Co-Regulation of Sirtuin 4 and 6 Expression. | 2018 | Details |
| A52247 | 29705001 | Biomaterials | Dendritic peptide bolaamphiphiles for siRNA delivery to primary adipocytes. | 2018 | Details |
| A52252 | 29681858 | Front Pharmacol | Aqueous Extract of Black Maca Prevents Metabolism Disorder via Regulating the Glycolysis/Gluconeogenesis-TCA Cycle and PPARα Signaling Activation in Golden Hamsters Fed a High-Fat, High-Fructose Diet. | 2018 | Details |
| A52253 | 29677105 | Molecules | The Chemical Composition and Metabolic Effects of Attalea phalerata Nut Oil in Hyperlipidemic Rats Induced by a High-Fructose Diet. | 2018 | Details |
| A52255 | 29659562 | PLoS Biol | Organic cation transporter 1 (OCT1) modulates multiple cardiometabolic traits through effects on hepatic thiamine content. | 2018 | Details |
| A52266 | 29484800 | Aging Cell | Changes at the nuclear lamina alter binding of pioneer factor Foxa2 in aged liver. | 2018 | Details |
| A52269 | 29453696 | Heart Fail Rev | Interrelationship between diabetes mellitus and heart failure: the role of peroxisome proliferator-activated receptors in left ventricle performance. | 2018 | Details |
| A52274 | 29404419 | mSphere | Anaplerotic Role of Glucose in the Oxidation of Endogenous Fatty Acids during Dengue Virus Infection. | 2018 | Details |
| A52281 | 29331507 | Mol Metab | Adropin: An endocrine link between the biological clock and cholesterol homeostasis. | 2017 | Details |
| A52282 | 29329215 | Nutrients | Dietary Supplement of Large Yellow Tea Ameliorates Metabolic Syndrome and Attenuates Hepatic Steatosis in db/db Mice. | 2018 | Details |
| A52286 | 29173222 | Br J Nutr | Maternal conjugated linoleic acid modulates TAG metabolism in adult rat offspring. | 2017 | Details |
| A52287 | 29115530 | Mol Med Rep | Curcumin suppresses Notch‑1 signaling: Improvements in fatty liver and insulin resistance in rats. | 2017 | Details |
| A52296 | 28986283 | Biochim Biophys Acta Mol Cell Biol Lipids | Effects of high-fat diet and age on the blood lipidome and circulating endocannabinoids of female C57BL/6 mice. | 2017 | Details |
| A52304 | 28867797 | Nutrients | Flavonoid-Rich Extract of Paulownia fortunei Flowers Attenuates Diet-Induced Hyperlipidemia, Hepatic Steatosis and Insulin Resistance in Obesity Mice by AMPK Pathway. | 2017 | Details |
| A52308 | 28811612 | Sci Rep | Coenzyme Q10 Improves Lipid Metabolism and Ameliorates Obesity by Regulating CaMKII-Mediated PDE4 Inhibition. | 2017 | Details |
| A52309 | 28811294 | Am J Physiol Endocrinol Metab | Dihydrocapsiate improved age-associated impairments in mice by increasing energy expenditure. | 2017 | Details |
| A52315 | 28759094 | J Am Osteopath Assoc | Conversion of Sugar to Fat: Is Hepatic de Novo Lipogenesis Leading to Metabolic Syndrome and Associated Chronic Diseases? | 2017 | Details |
| A52317 | 28739173 | Biochim Biophys Acta Mol Basis Dis | Lipid droplet proteins and metabolic diseases. | 2017 | Details |
| A52323 | 28661066 | NMR Biomed | Sexual dimorphism in hepatic lipids is associated with the evolution of metabolic status in mice. | 2017 | Details |
| A52327 | 28545035 | Oncotarget | Novel PPARα agonist MHY553 alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during aging. | 2017 | Details |
| A52331 | 28486481 | PLoS One | Temporal changes in sphingolipids and systemic insulin sensitivity during the transition from gestation to lactation. | 2017 | Details |
| A52335 | 28420093 | Int J Mol Sci | Potential Role of Free Fatty Acids in the Pathogenesis of Periodontitis and Primary Sjögren's Syndrome. | 2017 | Details |
| A52344 | 28378930 | Hepatology | Hepatic FXR/SHP axis modulates systemic glucose and fatty acid homeostasis in aged mice. | 2017 | Details |
| A52350 | 28267248 | Mol Nutr Food Res | Lycopene and tomato powder supplementation similarly inhibit high-fat diet induced obesity, inflammatory response, and associated metabolic disorders. | 2017 | Details |
| A52351 | 28259688 | J Invest Dermatol | Hair Growth Cycle Is Arrested in SCD1 Deficiency by Impaired Wnt3a-Palmitoleoylation and Retrieved by the Artificial Lipid Barrier. | 2017 | Details |
| A52352 | 28256090 | Aging Cell | Sterol regulatory element-binding protein-1c orchestrates metabolic remodeling of white adipose tissue by caloric restriction. | 2017 | Details |
| A52359 | 28213130 | Biochem Biophys Res Commun | Dipeptidyl peptidase-4 impairs insulin signaling and promotes lipid accumulation in hepatocytes. | 2017 | Details |
| A52362 | 28189603 | Mol Genet Metab | UX007 for the treatment of long chain-fatty acid oxidation disorders: Safety and efficacy in children and adults following 24weeks of treatment. | 2017 | Details |
| A52368 | 28100772 | J Biol Chem | De Novo Sphingolipid Biosynthesis Is Required for Adipocyte Survival and Metabolic Homeostasis. | 2017 | Details |
| A52380 | 27884961 | J Lipid Res | Therapeutic silencing of fat-specific protein 27 improves glycemic control in mouse models of obesity and insulin resistance. | 2016 | Details |
| A52382 | 27852124 | Am J Chin Med | Metabolic Profiling of Liver Tissue in Diabetic Mice Treated with Artemisia Capillaris and Alisma Rhizome Using LC-MS and CE-MS. | 2016 | Details |
| A52387 | 27799461 | J Endocrinol | Hepatocyte-specific, PPARγ-regulated mechanisms to promote steatosis in adult mice. | 2016 | Details |
| A52397 | 27659144 | Trends Endocrinol Metab | Perilipin 2 and Age-Related Metabolic Diseases: A New Perspective. | 2016 | Details |
| A52403 | 27568222 | EBioMedicine | Transgenic Adipose-specific Expression of the Nuclear Receptor RORα Drives a Striking Shift in Fat Distribution and Impairs Glycemic Control. | 2016 | Details |
| A52404 | 27552247 | Endocrinology | Nonnuclear Estrogen Receptor Activation Improves Hepatic Steatosis in Female Mice. | 2016 | Details |
| A52407 | 27533883 | Environ Toxicol | Exposure to an environmentally relevant mixture of organochlorine compounds and polychlorinated biphenyls Promotes hepatic steatosis in male Ob/Ob mice. | 2016 | Details |
| A52410 | 27405874 | Anal Bioanal Chem | Metabolomics profiling of the free and total oxidised lipids in urine by LC-MS/MS: application in patients with rheumatoid arthritis. | 2016 | Details |
| A52412 | 27382035 | Am J Physiol Endocrinol Metab | Targeting ceramide metabolism in obesity. | 2016 | Details |
| A52421 | 27302175 | Exp Biol Med (Maywood) | Regulation of lipid deposition in farm animals: Parallels between agriculture and human physiology. | 2016 | Details |
| A52422 | 27285689 | J Anim Sci | Effects of a six-week intraduodenal supplementation with quercetin on liver lipid metabolism and oxidative stress in peripartal dairy cows. | 2016 | Details |
| A52428 | 27216817 | Nucleic Acids Res | Dysregulated signaling hubs of liver lipid metabolism reveal hepatocellular carcinoma pathogenesis. | 2016 | Details |
| A52430 | 27203212 | Oncotarget | Organochloride pesticides induced hepatic ABCG5/G8 expression and lipogenesis in Chinese patients with gallstone disease. | 2016 | Details |
| A52435 | 27163748 | Int J Obes (Lond) | Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor. | 2016 | Details |
| A52440 | 27107678 | Gene | Integrative functional genomic analysis unveils the differing dysregulated metabolic processes across hepatocellular carcinoma stages. | 2016 | Details |
| A52443 | 27089994 | Int J Obes (Lond) | Isocaloric high-fat feeding directs hepatic metabolism to handling of nutrient imbalance promoting liver fat deposition. | 2016 | Details |
| A52444 | 27086014 | Anal Bioanal Chem | Development and application of a comprehensive lipidomic analysis to investigate Tripterygium wilfordii-induced liver injury. | 2016 | Details |
| A52450 | 27021137 | Mol Biosyst | A lipidomics investigation into the intervention of celastrol in experimental colitis. | 2016 | Details |
| A52453 | 26980761 | Cancer Res | Oncoprotein HBXIP Modulates Abnormal Lipid Metabolism and Growth of Breast Cancer Cells by Activating the LXRs/SREBP-1c/FAS Signaling Cascade. | 2016 | Details |
| A52455 | 26964726 | Obes Res Clin Pract | Predictive value of serum dihomo-γ-linolenic acid level and estimated Δ-5 desaturase activity in patients with hepatic steatosis. | 2016 | Details |
| A52457 | 26927351 | Ann Clin Lab Sci | Rare Korean Cases of Very-long-chain Acyl-CoA Dehydrogenase Deficiency with a Novel Recurrent Mutation. | 2016 | Details |
| A52460 | 26901091 | Endocrinology | Overexpression of β-Klotho in Adipose Tissue Sensitizes Male Mice to Endogenous FGF21 and Provides Protection From Diet-Induced Obesity. | 2016 | Details |
| A52478 | 26520282 | Arab J Gastroenterol | Chanarin-Dorfman syndrome: A case report and review of the literature. | 2015 | Details |
| A52479 | 26515918 | Obes Res Clin Pract | Hepatitis B e antigen-positive and high levels of alanine aminotransferase are associated with prevalence of metabolic syndrome in chronic HBV patients. | 2015 | Details |
| A52484 | 26475180 | Nutr Res | Prevention of hyperphagia prevents ovariectomy-induced triacylglycerol accumulation in liver, but not plasma. | 2015 | Details |
| A52486 | 26464614 | Int J Clin Exp Pathol | Lipid droplet-associated proteins in alcoholic liver disease: a potential linkage with hepatocellular damage. | 2015 | Details |
| A52488 | 26439934 | PLoS One | Association of a Human FABP1 Gene Promoter Region Polymorphism with Altered Serum Triglyceride Levels. | 2015 | Details |
| A52489 | 26439088 | J Clin Endocrinol Metab | The Genetic Variant I148M in PNPLA3 Is Associated With Increased Hepatic Retinyl-Palmitate Storage in Humans. | 2015 | Details |