Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A52494 | 26382148 | J Vis Exp | Determination of Fatty Acid Oxidation and Lipogenesis in Mouse Primary Hepatocytes. | 2015 | Details |
| A52501 | 26287659 | Int J Dev Neurosci | Short term exendin-4 treatment reduces markers of metabolic disorders in female offspring of obese rat dams. | 2015 | Details |
| A52508 | 26250749 | Cytokine Growth Factor Rev | Mechanisms of enterohepatic fibroblast growth factor 15/19 signaling in health and disease. | 2015 | Details |
| A52515 | 26152236 | J Agric Food Chem | Dietary (-)-Epigallocatechin-3-gallate Supplementation Counteracts Aging-Associated Skeletal Muscle Insulin Resistance and Fatty Liver in Senescence-Accelerated Mouse. | 2015 | Details |
| A52516 | 26147095 | PLoS One | Perilipin-2 Modulates Lipid Absorption and Microbiome Responses in the Mouse Intestine. | 2015 | Details |
| A52517 | 26119995 | Int J Obes (Lond) | Leptin-induced mitochondrial fusion mediates hepatic lipid accumulation. | 2015 | Details |
| A52518 | 26112408 | J Biol Chem | Lipid-induced Muscle Insulin Resistance Is Mediated by GGPPS via Modulation of the RhoA/Rho Kinase Signaling Pathway. | 2015 | Details |
| A52523 | 26059381 | Nutrition | Conjugated linoleic acid reduces visceral and ectopic lipid accumulation and insulin resistance in chronic severe hypertriacylglycerolemia. | 2015 | Details |
| A52541 | 25805830 | FASEB J | Activated Kupffer cells inhibit insulin sensitivity in obese mice. | 2015 | Details |
| A52544 | 25749935 | J Physiol Biochem | Gut microbiota: a key player in health and disease. A review focused on obesity. | 2015 | Details |
| A52547 | 25723909 | Appl Physiol Nutr Metab | Carnitine supplementation alleviates lipid metabolism derangements and protects against oxidative stress in non-obese hereditary hypertriglyceridemic rats. | 2015 | Details |
| A52555 | 25645248 | Obesity (Silver Spring) | Interleukin-32β ameliorates metabolic disorder and liver damage in mice fed high-fat diet. | 2015 | Details |
| A52557 | 25633982 | Dis Model Mech | Zebrafish as a model for apolipoprotein biology: comprehensive expression analysis and a role for ApoA-IV in regulating food intake. | 2015 | Details |
| A52558 | 25632931 | Semin Liver Dis | MicroRNAs in fatty liver disease. | 2015 | Details |
| A52569 | 25497809 | J Dairy Sci | Body condition score at calving affects systemic and hepatic transcriptome indicators of inflammation and nutrient metabolism in grazing dairy cows. | 2014 | Details |
| A52574 | 25445284 | Gene | L-Carnitine intake prevents irregular feeding-induced obesity and lipid metabolism disorder. | 2014 | Details |
| A52583 | 25376159 | J Gastroenterol Hepatol | Hepatic fat, not visceral fat, is associated with gallbladder polyps: a study of 2643 healthy subjects. | 2015 | Details |
| A52587 | 25329603 | Nutr Diabetes | Altered levels of serum sphingomyelin and ceramide containing distinct acyl chains in young obese adults. | 2014 | Details |
| A52594 | 25203718 | Hepatology | Effect of sofosbuvir and ribavirin treatment on peripheral and hepatic lipid metabolism in chronic hepatitis C virus, genotype 1-infected patients. | 2015 | Details |
| A52596 | 25184990 | Am J Physiol Endocrinol Metab | MicroRNA regulation of mitochondrial and ER stress signaling pathways: implications for lipoprotein metabolism in metabolic syndrome. | 2014 | Details |
| A52610 | 24944901 | Mol Metab | Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation. | 2014 | Details |
| A52614 | 24871327 | Circ Cardiovasc Genet | The WWOX gene modulates high-density lipoprotein and lipid metabolism. | 2014 | Details |
| A52621 | 24707127 | World J Gastroenterol | Immunologic, metabolic and genetic factors in hepatitis C virus infection. | 2014 | Details |
| A52624 | 24659875 | World J Gastroenterol | Hepatitis C virus and metabolic disorder interactions towards liver damage and atherosclerosis. | 2014 | Details |
| A52626 | 24648546 | FASEB J | Food withdrawal lowers energy expenditure and induces inactivity in long-chain fatty acid oxidation-deficient mouse models. | 2014 | Details |
| A52628 | 24605027 | World J Gastroenterol | Role of abnormal lipid metabolism in development, progression, diagnosis and therapy of pancreatic cancer. | 2014 | Details |
| A52630 | 24531926 | J Inherit Metab Dis | Aberrant protein acylation is a common observation in inborn errors of acyl-CoA metabolism. | 2014 | Details |
| A52643 | 24260478 | PLoS One | Deep sequencing of small RNA repertoires in mice reveals metabolic disorders-associated hepatic miRNAs. | 2013 | Details |
| A52651 | 24146946 | PLoS One | Effects of taurine supplementation on hepatic markers of inflammation and lipid metabolism in mothers and offspring in the setting of maternal obesity. | 2013 | Details |
| A52656 | 24069385 | PLoS One | SCD1 Expression is dispensable for hepatocarcinogenesis induced by AKT and Ras oncogenes in mice. | 2013 | Details |
| A52657 | 24069029 | Front Genet | Temporal clustering of gene expression links the metabolic transcription factor HNF4α to the ER stress-dependent gene regulatory network. | 2013 | Details |
| A52669 | 23874434 | PLoS One | Dynamic regulation of hepatic lipid droplet properties by diet. | 2013 | Details |
| A52671 | 23824421 | J Clin Endocrinol Metab | Metabolic consequences of adipose triglyceride lipase deficiency in humans: an in vivo study in patients with neutral lipid storage disease with myopathy. | 2013 | Details |
| A52675 | 23746045 | J Proteome Res | High-fat diet induces dynamic metabolic alterations in multiple biological matrices of rats. | 2013 | Details |
| A52676 | 23740690 | EMBO Mol Med | Balancing the fat: lipid droplets and human disease. | 2013 | Details |
| A52681 | 23619368 | Curr Opin Lipidol | Dietary fatty acids and lipoprotein metabolism: new insights and updates. | 2013 | Details |
| A52682 | 23609963 | J Endocrinol Invest | Liver X receptors, nervous system, and lipid metabolism. | 2013 | Details |
| A52683 | 23565157 | PLoS One | A metabolomic analysis of two intravenous lipid emulsions in a murine model. | 2013 | Details |
| A52685 | 23551521 | J Intern Med | Ectopic lipid storage and insulin resistance: a harmful relationship. | 2013 | Details |
| A52686 | 23550081 | Endocr Rev | Adiposity and insulin resistance in humans: the role of the different tissue and cellular lipid depots. | 2013 | Details |
| A52688 | 23511381 | Curr Opin Lipidol | Alcohol and plasma triglycerides. | 2013 | Details |
| A52692 | 23448543 | J Proteome Res | Paraoxonase-1 deficiency is associated with severe liver steatosis in mice fed a high-fat high-cholesterol diet: a metabolomic approach. | 2013 | Details |
| A52694 | 23431266 | PLoS Biol | Partial inhibition of adipose tissue lipolysis improves glucose metabolism and insulin sensitivity without alteration of fat mass. | 2013 | Details |
| A52698 | 23347084 | Histopathology | Adipophilin/perilipin-2 as a lipid droplet-specific marker for metabolically active cells and diseases associated with metabolic dysregulation. | 2013 | Details |
| A52699 | 23341867 | PLoS One | Angiotensin AT(2) receptor contributes towards gender bias in weight gain. | 2013 | Details |
| A52701 | 23317789 | Prog Mol Biol Transl Sci | Adiponectin receptors in energy homeostasis and obesity pathogenesis. | 2013 | Details |
| A52707 | 23176795 | Nutr Res | Genistein reduced insulin resistance index through modulating lipid metabolism in ovariectomized rats. | 2012 | Details |
| A52708 | 23139775 | PLoS One | Heterogeneity of the Stearoyl-CoA desaturase-1 (SCD1) gene and metabolic risk factors in the EPIC-Potsdam study. | 2012 | Details |
| A52710 | 23118444 | J Lipid Res | AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism. | 2012 | Details |
| A52714 | 23043895 | Trends Endocrinol Metab | Dissociating fatty liver and diabetes. | 2012 | Details |
| A52715 | 23033902 | Biosci Rep | Trans-Golgi proteins participate in the control of lipid droplet and chylomicron formation. | 2013 | Details |
| A52717 | 22925001 | Br J Pharmacol | Small molecule glucokinase activators disturb lipid homeostasis and induce fatty liver in rodents: a warning for therapeutic applications in humans. | 2013 | Details |
| A52719 | 22884994 | Toxicol Appl Pharmacol | Hepatic lipid profiling of deer mice fed ethanol using ¹H and ³¹P NMR spectroscopy: a dose-dependent subchronic study. | 2012 | Details |
| A52735 | 22662228 | PLoS One | Involvement of SIK3 in glucose and lipid homeostasis in mice. | 2012 | Details |
| A52738 | 22619174 | J Biol Chem | Abcb11 deficiency induces cholestasis coupled to impaired β-fatty acid oxidation in mice. | 2012 | Details |
| A52739 | 22564914 | Mol Cell Endocrinol | Hepatic growth hormone and glucocorticoid receptor signaling in body growth, steatosis and metabolic liver cancer development. | 2012 | Details |
| A52740 | 22547685 | Mol Cell Biol | BNip3 regulates mitochondrial function and lipid metabolism in the liver. | 2012 | Details |
| A52753 | 22428554 | J Immunotoxicol | Effects of pioglitazone and/or simvastatin on circulating TNFα and adiponectin levels in insulin resistance. | 2012 | Details |
| A52756 | 22414273 | J Gastroenterol Hepatol | Cholesteryl ester transfer protein gene polymorphisms increase the risk of fatty liver in females independent of adiposity. | 2012 | Details |
| A52759 | 22382323 | Biol Pharm Bull | Fenretinide ameliorates insulin resistance and fatty liver in obese mice. | 2012 | Details |
| A52761 | 22350143 | J Nat Med | Puerariae flos alleviates metabolic diseases in Western diet-loaded, spontaneously obese type 2 diabetic model mice. | 2012 | Details |
| A52765 | 22309199 | J Proteome Res | Mitochondrial acetylome analysis in a mouse model of alcohol-induced liver injury utilizing SIRT3 knockout mice. | 2012 | Details |
| A52792 | 21856370 | Biochimie | Human liver fatty acid binding protein (hFABP1) gene is regulated by liver-enriched transcription factors HNF3β and C/EBPα. | 2011 | Details |
| A52796 | 21817098 | Arterioscler Thromb Vasc Biol | CD40L deficiency ameliorates adipose tissue inflammation and metabolic manifestations of obesity in mice. | 2011 | Details |
| A52801 | 21723507 | Cell Metab | Heat shock transcription factor 1 is a key determinant of HCC development by regulating hepatic steatosis and metabolic syndrome. | 2011 | Details |
| A52811 | 21459324 | Cell Metab | Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia. | 2011 | Details |
| A52815 | 21386801 | Int J Obes (Lond) | Coordinated improvement in glucose tolerance, liver steatosis and obesity-associated inflammation by cannabinoid 1 receptor antagonism in fat Aussie mice. | 2011 | Details |
| A52818 | 21336545 | Naunyn Schmiedebergs Arch Pharmacol | Overweight induced by chronic risperidone exposure is correlated with overexpression of the SREBP-1c and FAS genes in mouse liver. | 2011 | Details |
| A52820 | 21318871 | Methods Mol Biol | Transgenic rodents with altered SSAT expression as models of pancreatitis and altered glucose and lipid metabolism. | 2011 | Details |
| A52821 | 21310864 | J Nutr | Dietary whey protein lowers the risk for metabolic disease in mice fed a high-fat diet. | 2011 | Details |
| A52831 | 21178610 | Curr Opin Clin Nutr Metab Care | Fatty acid regulation of hepatic lipid metabolism. | 2011 | Details |
| A52833 | 21145849 | J Hepatol | Drug-induced toxicity on mitochondria and lipid metabolism: mechanistic diversity and deleterious consequences for the liver. | 2010 | Details |
| A52834 | 21112030 | Best Pract Res Clin Endocrinol Metab | Metabolic consequences of intermittent hypoxia: relevance to obstructive sleep apnea. | 2010 | Details |
| A52846 | 20832799 | Atherosclerosis | High-fat diet without excess calories induces metabolic disorders and enhances atherosclerosis in rabbits. | 2010 | Details |
| A52850 | 20699090 | Clin Chim Acta | Triglycerides and gallstone formation. | 2010 | Details |
| A52853 | 20670429 | Lipids Health Dis | Glycyrrhizic acid improved lipoprotein lipase expression, insulin sensitivity, serum lipid and lipid deposition in high-fat diet-induced obese rats. | 2010 | Details |
| A52866 | 20487553 | BMC Gastroenterol | Nutrigenomics therapy of hepatisis C virus induced-hepatosteatosis. | 2010 | Details |
| A52874 | 20361178 | Diabetologia | Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009. | 2010 | Details |
| A52875 | 20340066 | Horm Metab Res | Leptin treatment during lactation programs leptin synthesis, intermediate metabolism, and liver microsteatosis in adult rats. | 2010 | Details |
| A52877 | 20332082 | Mol Cell Proteomics | Lipogenesis is decreased by grape seed proanthocyanidins according to liver proteomics of rats fed a high fat diet. | 2010 | Details |
| A52878 | 20197195 | Metabolism | Impact of dietary fat type within the context of altered cholesterol homeostasis on cholesterol and lipoprotein metabolism in the F1B hamster. | 2010 | Details |
| A52883 | 20106640 | Nutr Metab Cardiovasc Dis | Association of increased visfatin/PBEF/NAMPT circulating concentrations and gene expression levels in peripheral blood cells with lipid metabolism and fatty liver in human morbid obesity. | 2010 | Details |
| A52887 | 19996744 | Curr Opin Clin Nutr Metab Care | Fatty acid interactions with genetic polymorphisms for cardiovascular disease. | 2010 | Details |
| A52890 | 19932908 | J Surg Res | Hepatocellular carcinoma associated lipid metabolism reprogramming. | 2009 | Details |
| A52892 | 19875992 | Obesity (Silver Spring) | The relationship of ectopic lipid accumulation to cardiac and vascular function in obesity and metabolic syndrome. | 2009 | Details |
| A52894 | 19854061 | Trends Endocrinol Metab | Hepatitis C virus hijacks host lipid metabolism. | 2009 | Details |
| A52900 | 19808675 | J Biol Chem | Hepatitis C virus proteins induce lipogenesis and defective triglyceride secretion in transgenic mice. | 2009 | Details |
| A52902 | 19796707 | Biochim Biophys Acta | Hypothalamic lipotoxicity and the metabolic syndrome. | 2009 | Details |
| A52903 | 19796705 | Biochim Biophys Acta | Lipotoxicity in macrophages: evidence from diseases associated with the metabolic syndrome. | 2009 | Details |
| A52904 | 19773738 | Int J Obes (Lond) | Chronic increase of circulating galanin levels induces obesity and marked alterations in lipid metabolism similar to metabolic syndrome. | 2009 | Details |
| A52907 | 19729476 | Am J Pathol | Tacrolimus ameliorates metabolic disturbance and oxidative stress caused by hepatitis C virus core protein: analysis using mouse model and cultured cells. | 2009 | Details |
| A52916 | 19564844 | Lab Invest | Adiponectin deficiency impairs liver regeneration through attenuating STAT3 phosphorylation in mice. | 2009 | Details |
| A52919 | 19528226 | Mol Cell Biol | Hypoxia-inducible factor 2 regulates hepatic lipid metabolism. | 2009 | Details |
| A52927 | 19421860 | Apoptosis | Diabetes and apoptosis: lipotoxicity. | 2009 | Details |
| A52930 | 19390516 | Obesity (Silver Spring) | High energy digestion efficiency and altered lipid metabolism contribute to obesity in BFMI mice. | 2009 | Details |
| A52932 | 19358089 | Exp Clin Endocrinol Diabetes | Adipose tissue dysfunction in obesity. | 2009 | Details |
| A52941 | 19148799 | J Gastroenterol | Steatosis, liver injury, and hepatocarcinogenesis in hepatitis C viral infection. | 2009 | Details |
| A52946 | 19148125 | Obesity (Silver Spring) | Prevention and reversal of obesity and glucose intolerance in mice by DHA derivatives. | 2009 | Details |
| A52948 | 20300478 | PPAR Res | PPAR/RXR Regulation of Fatty Acid Metabolism and Fatty Acid omega-Hydroxylase (CYP4) Isozymes: Implications for Prevention of Lipotoxicity in Fatty Liver Disease. | 2010 | Details |
| A52955 | 18930334 | J Hepatol | Dietary resveratrol alters lipid metabolism-related gene expression of mice on an atherogenic diet. | 2008 | Details |