Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A43201 | 32316687 | Nutrients | Shikonin Attenuates Hepatic Steatosis by Enhancing Beta Oxidation and Energy Expenditure via AMPK Activation. | 2020 | Details |
| A43208 | 32282399 | Eur J Gastroenterol Hepatol | Liver stiffness across different chronic liver disease under therapy with statin in a real life cohort. | 2021 | Details |
| A43230 | 32229664 | J Basic Clin Physiol Pharmacol | Altered composition of high-lipid diet may generate reactive oxygen species by disturbing the balance of antioxidant and free radicals. | 2020 | Details |
| A43234 | 32222527 | Exp Parasitol | The acute schistosomiasis mansoni ameliorates metabolic syndrome in the C57BL/6 mouse model. | 2020 | Details |
| A43240 | 32205228 | Food Chem Toxicol | Blood BTEXS and heavy metal levels are associated with liver injury and systemic inflammation in Gulf states residents. | 2020 | Details |
| A43310 | 32011389 | Eur J Gastroenterol Hepatol | Increased prevalence of portal vein thrombosis in patients with nonalcoholic steatohepatitis-cirrhosis due to increased proinflammatory cytokines releasing from abdominal adipose tissue. | 2020 | Details |
| A43395 | 31845444 | Phytother Res | Bitter melon fruit extract has a hypoglycemic effect and reduces hepatic lipid accumulation in ob/ob mice. | 2019 | Details |
| A43460 | 31663469 | Curr Med Chem | Effects of Pterostilbene on Diabetes, Liver Steatosis and Serum Lipids. | 2021 | Details |
| A43473 | 31617122 | Ann Surg Oncol | Prediction of Recurrence Patterns from Hepatic Parenchymal Disease After Resection of Colorectal Liver Metastases. | 2019 | Details |
| A43501 | 31576541 | Adv Exp Med Biol | Contributing Roles of CYP2E1 and Other Cytochrome P450 Isoforms in Alcohol-Related Tissue Injury and Carcinogenesis. | 2019 | Details |
| A43535 | 31483154 | Am J Physiol Regul Integr Comp Physiol | Loss of hepatic PPARα promotes inflammation and serum hyperlipidemia in diet-induced obesity. | 2019 | Details |
| A43537 | 31475778 | J Cell Mol Med | Protective role of melatonin in early-stage and end-stage liver cirrhosis. | 2019 | Details |
| A43557 | 31419141 | J Med Chem | Development of the First Low Nanomolar Liver Receptor Homolog-1 Agonist through Structure-guided Design. | 2019 | Details |
| A43560 | 31408938 | Molecules | Resveratrol Maintains Lipid Metabolism Homeostasis via One of the Mechanisms Associated with the Key Circadian Regulator Bmal1. | 2019 | Details |
| A43587 | 31345023 | J Agric Food Chem | Processed Meat Protein Promoted Inflammation and Hepatic Lipogenesis by Upregulating Nrf2/Keap1 Signaling Pathway in Glrx-Deficient Mice. | 2019 | Details |
| A43589 | 31341440 | Integr Med (Encinitas) | Barrie Tan, PhD: Using Tocotrienols to Address Lifestyle and Metabolic Disease. | 2019 | Details |
| A43610 | 31296380 | Biochem Biophys Res Commun | Spinal miR-34a regulates inflammatory pain by targeting SIRT1 in complete Freund's adjuvant mice. | 2019 | Details |
| A43628 | 31253430 | J Pharmacol Sci | A novel AMPK activator improves hepatic lipid metabolism and leukocyte trafficking in experimental hepatic steatosis. | 2019 | Details |
| A43639 | 31237448 | Am J Physiol Endocrinol Metab | Obeticholic acid ameliorates dyslipidemia but not glucose tolerance in mouse model of gestational diabetes. | 2019 | Details |
| A43646 | 31225638 | Br J Dermatol | Management of psoriasis as a systemic disease: what is the evidence? | 2019 | Details |
| A43648 | 31213365 | J Hepatol | Unveiling the depletion of Kupffer cells in experimental hepatocarcinogenesis through liver macrophage subtype-specific markers. | 2019 | Details |
| A43657 | 31168510 | Hepatol Commun | Protective Function of Mitogen-Activated Protein Kinase Phosphatase 5 in Aging- and Diet-Induced Hepatic Steatosis and Steatohepatitis. | 2019 | Details |
| A43676 | 31132831 | Korean J Gastroenterol | [Hepatobiliary Manifestation of Inflammatory Bowel Disease]. | 2019 | Details |
| A43683 | 31106419 | J Cell Physiol | Impact of different ectopic fat depots on cardiovascular and metabolic diseases. | 2019 | Details |
| A43726 | 31018107 | Annu Rev Nutr | Bile Acids as Metabolic Regulators and Nutrient Sensors. | 2019 | Details |
| A43759 | 30947871 | Clin Liver Dis | Hepatic Complications of Inflammatory Bowel Disease. | 2019 | Details |
| A43762 | 30945509 | Zhen Ci Yan Jiu | [Progress of researches on mechanisms of acupuncture therapy for insulin resistance]. | 2019 | Details |
| A43781 | 30894877 | Evid Based Complement Alternat Med | BuShenKangShuai Tablet Alleviates Hepatic Steatosis via Improving Liver Adiponectin Resistance in ApoE-/- Mice. | 2019 | Details |
| A43783 | 30890204 | Gene Expr | Sterol 12α-Hydroxylase Aggravates Dyslipidemia by Activating the Ceramide/mTORC1/SREBP-1C Pathway via FGF21 and FGF15. | 2019 | Details |
| A43784 | 30888627 | Hepatol Int | Curcumin as a potential therapeutic option for NAFLD and other metabolic diseases: need for establishing the underlying mechanism(s) of action. | 2019 | Details |
| A43785 | 30888019 | Inflamm Bowel Dis | Reply to "Transient Elastography in IBD Patients". | 2019 | Details |
| A43786 | 30888016 | Inflamm Bowel Dis | Transient Elastography in IBD Patients. | 2019 | Details |
| A43809 | 30831126 | Life Sci | The relevance of pyroptosis in the pathogenesis of liver diseases. | 2019 | Details |
| A43821 | 30791762 | Expert Rev Gastroenterol Hepatol | Apoptosis signal-regulating kinase-1 as a therapeutic target in nonalcoholic fatty liver disease. | 2019 | Details |
| A43838 | 30741841 | J Clin Gastroenterol | Thirty Years of Lactobacillus rhamnosus GG: A Review. | 2019 | Details |
| A43843 | 30721959 | Adv Nutr | Mechanisms of Action of Probiotics. | 2019 | Details |
| A43857 | 30670473 | J Lipid Res | Hepatocyte sortilin 1 knockout and treatment with a sortilin 1 inhibitor reduced plasma cholesterol in Western diet-fed mice. | 2019 | Details |
| A43873 | 30629464 | FASEB J | Maternal prebiotic supplementation reduces fatty liver development in offspring through altered microbial and metabolomic profiles in rats. | 2019 | Details |
| A43920 | 30454825 | Clin Liver Dis | Histopathology of Alcohol-Related Liver Diseases. | 2019 | Details |
| A43942 | 30387829 | Mol Med Rep | Nobiletin alleviates palmitic acid‑induced NLRP3 inflammasome activation in a sirtuin 1‑dependent manner in AML‑12 cells. | 2018 | Details |
| A43998 | 30185915 | Nat Rev Gastroenterol Hepatol | Inflammasomes in the gastrointestinal tract: infection, cancer and gut microbiota homeostasis. | 2018 | Details |
| A44001 | 30174510 | Saudi J Biol Sci | Effects of a medicinal plant Macrotyloma uniflorum (Lam.) Verdc.formulation (MUF) on obesity-associated oxidative stress-induced liver injury. | 2018 | Details |
| A44032 | 30080294 | Phytother Res | Milk thistle (Silybum marianum): A concise overview on its chemistry, pharmacological, and nutraceutical uses in liver diseases. | 2018 | Details |
| A44055 | 30023266 | J Microsc Ultrastruct | Histological, Immunohistochemical, and Biochemical Study of Experimentally Induced Fatty Liver in Adult Male Albino Rat and the Possible Protective Role of Pomegranate. | 2020 | Details |
| A44059 | 30014902 | Redox Biol | Polydatin prevents fructose-induced liver inflammation and lipid deposition through increasing miR-200a to regulate Keap1/Nrf2 pathway. | 2018 | Details |
| A44065 | 29993258 | Crit Rev Food Sci Nutr | The target cells of anthocyanins in metabolic syndrome. | 2018 | Details |
| A44068 | 29973533 | Nutrients | Kahweol Ameliorates the Liver Inflammation through the Inhibition of NF-κB and STAT3 Activation in Primary Kupffer Cells and Primary Hepatocytes. | 2018 | Details |
| A44069 | 29967757 | PeerJ | Huperzine A attenuates nonalcoholic fatty liver disease by regulating hepatocyte senescence and apoptosis: an in vitro study. | 2018 | Details |
| A44091 | 29785143 | J Exp Pharmacol | Pilot study of the antifibrotic effects of the multikinase inhibitor pacritinib in a mouse model of liver fibrosis. | 2018 | Details |
| A44095 | 29768109 | J Am Coll Nutr | Effects of Phytosterol Supplementation on Serum Levels of Lipid Profiles, Liver Enzymes, Inflammatory Markers, Adiponectin, and Leptin in Patients Affected by Nonalcoholic Fatty Liver Disease: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial. | 2018 | Details |
| A44118 | 29694888 | Cell Rep | Gut Microbiota-Derived Tryptophan Metabolites Modulate Inflammatory Response in Hepatocytes and Macrophages. | 2018 | Details |
| A44162 | 29546055 | Biomed Res Int | Liver Illness and Psoriatic Patients. | 2018 | Details |
| A44176 | 29507905 | Hepatol Commun | Pyrroloquinoline quinone prevents developmental programming of microbial dysbiosis and macrophage polarization to attenuate liver fibrosis in offspring of obese mice. | 2018 | Details |
| A44195 | 29454748 | Am J Pathol | Fatty Acid Binding Protein 4 (FABP4) Overexpression in Intratumoral Hepatic Stellate Cells within Hepatocellular Carcinoma with Metabolic Risk Factors. | 2018 | Details |
| A44205 | 29408544 | J Hepatol | Pyroptosis: An inflammatory link between NAFLD and NASH with potential therapeutic implications. | 2018 | Details |
| A44224 | 29342898 | Nutrients | Associations between Zinc Deficiency and Metabolic Abnormalities in Patients with Chronic Liver Disease. | 2018 | Details |
| A44251 | 29241748 | Clin Dermatol | Psoriasis and the metabolic syndrome. | 2017 | Details |
| A44276 | 29175112 | Pharmacol Res | Chalcones as putative hepatoprotective agents: Preclinical evidence and molecular mechanisms. | 2017 | Details |
| A44288 | 29149924 | Rheum Dis Clin North Am | Gastrointestinal and Hepatic Disease in Spondyloarthritis. | 2018 | Details |
| A44330 | 28980402 | Mol Nutr Food Res | Is Palmitoleic Acid a Plausible Nonpharmacological Strategy to Prevent or Control Chronic Metabolic and Inflammatory Disorders? | 2017 | Details |
| A44341 | 28914862 | Ter Arkh | [Liver diseases: The pathogenetic role of the gut microbiome and the potential of treatment for its modulation]. | 2017 | Details |
| A44342 | 28912810 | Int J Endocrinol | Latent Inflammation and Insulin Resistance in Adipose Tissue. | 2017 | Details |
| A44343 | 28910195 | Metab Syndr Relat Disord | Elevated Neutrophil-to-Lymphocyte Ratio in Metabolic Syndrome Is Associated with Increased Risk of Colorectal Adenoma. | 2017 | Details |
| A44347 | 28898219 | Nat Biotechnol | Nestlé moves into gut microbiome tests. | 2017 | Details |
| A44358 | 28859227 | Hepatology | Transmembrane BAX Inhibitor motif-containing 1, a novel anti-inflammatory approach for nonalcoholic steatohepatitis treatment. | 2018 | Details |
| A44359 | 28847030 | Semin Liver Dis | Macrophages in Nonalcoholic Fatty Liver Disease: A Role Model of Pathogenic Immunometabolism. | 2017 | Details |
| A44364 | 28834692 | J Mol Biol | Soluble Extracellular Domain of Death Receptor 5 Inhibits TRAIL-Induced Apoptosis by Disrupting Receptor-Receptor Interactions. | 2017 | Details |
| A44389 | 28736228 | Biochim Biophys Acta Gen Subj | DBZ is a putative PPARγ agonist that prevents high fat diet-induced obesity, insulin resistance and gut dysbiosis. | 2017 | Details |
| A44407 | 28694327 | Physiol Rep | Efficacy of nutritional interventions to lower circulating ceramides in young adults: FRUVEDomic pilot study. | 2017 | Details |
| A44420 | 28677122 | FEBS Lett | From chronic overnutrition to metaflammation and insulin resistance: adipose tissue and liver contributions. | 2017 | Details |
| A44421 | 28676901 | Dig Dis Sci | Does Metabolic Syndrome and Not the Inflammatory Load Predict Nonalcoholic Fatty Liver Disease Severity in Inflammatory Bowel Disease Patients? | 2017 | Details |
| A44452 | 28590260 | Curr Opin Clin Nutr Metab Care | Ghrelin and autophagy. | 2017 | Details |
| A44470 | 28514463 | JAMA Dermatol | Pediatric Psoriasis Comorbidity Screening Guidelines. | 2017 | Details |
| A44475 | 28506368 | Gastroenterol Clin North Am | Human Immunodeficiency Virus Infection, Antiretroviral Therapy, and Liver Pathology. | 2017 | Details |
| A44499 | 28463859 | Curr Opin Lipidol | Adiponectin, lipids and atherosclerosis. | 2017 | Details |
| A44505 | 28448873 | Biomed Pharmacother | Osthole attenuates lipid accumulation, regulates the expression of inflammatory mediators, and increases antioxidants in FL83B cells. | 2017 | Details |
| A44511 | 28409336 | Lipids | Dietary Docosahexaenoic Acid and trans-10, cis-12-Conjugated Linoleic Acid Differentially Alter Oxylipin Profiles in Mouse Periuterine Adipose Tissue. | 2017 | Details |
| A44540 | 28296825 | Inflamm Bowel Dis | Frequency and Risk Factors of Clostridium difficile Infection in Hospitalized Patients With Pouchitis: A Population-based Study. | 2017 | Details |
| A44546 | 28285710 | Cell Immunol | Role of immune cells in obesity induced low grade inflammation and insulin resistance. | 2017 | Details |
| A44558 | 28212760 | J Am Acad Dermatol | Psoriasis and comorbid diseases: Implications for management. | 2017 | Details |
| A44559 | 28212759 | J Am Acad Dermatol | Psoriasis and comorbid diseases: Epidemiology. | 2017 | Details |
| A44582 | 28096127 | Adv Nutr | Formation of Fructose-Mediated Advanced Glycation End Products and Their Roles in Metabolic and Inflammatory Diseases. | 2017 | Details |
| A44584 | 28092152 | FP Essent | Issues in Nutrition: Dietary Considerations in Select Chronic Conditions. | 2017 | Details |
| A44612 | 27981604 | Hepatology | Malondialdehyde epitopes are sterile mediators of hepatic inflammation in hypercholesterolemic mice. | 2017 | Details |
| A44615 | 27942586 | JCI Insight | IRF5 governs liver macrophage activation that promotes hepatic fibrosis in mice and humans. | 2016 | Details |
| A44625 | 27914812 | Biochem Biophys Res Commun | Protective effects of gomisin N against hepatic steatosis through AMPK activation. | 2016 | Details |
| A44657 | 27783862 | Compr Physiol | Adipose Tissue-Derived Plasminogen Activator Inhibitor-1 Function and Regulation. | 2016 | Details |
| A44673 | 27699898 | J Intern Med | Adipose tissue regulates insulin sensitivity: role of adipogenesis, de novo lipogenesis and novel lipids. | 2016 | Details |
| A44678 | 27435327 | Dig Dis Sci | Targeting Hepatic Fibrosis in Autoimmune Hepatitis. | 2016 | Details |
| A44701 | 27683821 | J Infect Dis | Direct-Acting Antiviral-Induced Hepatitis C Virus Clearance Does Not Completely Restore the Altered Cytokine and Chemokine Milieu in Patients With Chronic Hepatitis C. | 2016 | Details |
| A44702 | 27679730 | J Ultrason | Is a fatty pancreas a banal lesion? | 2016 | Details |
| A44709 | 27639178 | Hepatology | Extracellular vesicles released by hepatocytes from gastric infusion model of alcoholic liver disease contain a MicroRNA barcode that can be detected in blood. | 2016 | Details |
| A44713 | 27625607 | Front Pharmacol | Exercise-Induced Release of Pharmacologically Active Substances and Their Relevance for Therapy of Hepatic Injury. | 2016 | Details |
| A44726 | 27534992 | J Lipid Res | Cholesterol 7α-hydroxylase protects the liver from inflammation and fibrosis by maintaining cholesterol homeostasis. | 2016 | Details |
| A44732 | 27499712 | Gastroenterol Hepatol (N Y) | Metabolic Manifestations and Complications Associated With Chronic Hepatitis C Virus Infection. | 2016 | Details |
| A44754 | 27432221 | Mol Nutr Food Res | Prolonged feeding with green tea polyphenols exacerbates cholesterol-induced fatty liver disease in mice. | 2016 | Details |
| A44769 | 27364051 | J Am Coll Cardiol | Ectopic and Visceral Fat Deposition in Lean and Obese Patients With Type 2 Diabetes. | 2016 | Details |
| A44808 | 27252163 | Physiology (Bethesda) | Linking Gut Microbiota and Inflammation to Obesity and Insulin Resistance. | 2016 | Details |
| A44809 | 27243019 | Inflamm Intest Dis | Does the Intestinal Microbiota Explain Differences in the Epidemiology of Liver Disease between East and West? | 2016 | Details |
| A44838 | 27116685 | Pathobiology | Chitotriosidase: A New Inflammatory Marker in Diabetic Complications. | 2016 | Details |