Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Glutathione718 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A24621 | 22683933 | Toxicol In Vitro | Effects of palmitic acid on TNF-α-induced cytotoxicity in SK-Hep-1 cells. | 2012 | Details |
| A24658 | 25755421 | J Clin Exp Hepatol | Non-alcoholic Fatty Liver Disease: East Versus West. | 2012 | Details |
| A24825 | 22462240 | J Tradit Chin Med | Dangfei liganning capsules attenuate the susceptibility of rat nonalcoholic fatty liver to carbon tetrachloride toxicity. | 2011 | Details |
| A24937 | 22340678 | Liver Int | Identification of liver proteins altered by type 2 diabetes mellitus in obese subjects. | 2012 | Details |
| A24948 | 22327056 | Obesity (Silver Spring) | Lipoic acid improves mitochondrial function in nonalcoholic steatosis through the stimulation of sirtuin 1 and sirtuin 3. | 2012 | Details |
| A24957 | 22313887 | Zhong Xi Yi Jie He Xue Bao | [Effects of the mixture of Swertia pseudochinensis Hara and Silybum marianum Gaertn extracts on CCl(4)-induced liver injury in rats with non-alcoholic fatty liver disease]. | 2012 | Details |
| A25021 | 22240297 | J Proteomics | Changes in hepatic protein expression in spontaneously hypertensive rats suggest early stages of non-alcoholic fatty liver disease. | 2012 | Details |
| A25070 | 22197629 | Dig Liver Dis | Silibinin improves hepatic and myocardial injury in mice with nonalcoholic steatohepatitis. | 2011 | Details |
| A25115 | 22157544 | J Nutr | Green tea extract suppresses NFκB activation and inflammatory responses in diet-induced obese rats with nonalcoholic steatohepatitis. | 2011 | Details |
| A25222 | 22082335 | Chem Res Toxicol | Glutathione-deficient mice are susceptible to TCDD-Induced hepatocellular toxicity but resistant to steatosis. | 2011 | Details |
| A25225 | 22081873 | Comp Hepatol | The effect of cocoa supplementation on hepatic steatosis, reactive oxygen species and LFABP in a rat model of NASH. | 2011 | Details |
| A25236 | 22064361 | Free Radic Biol Med | Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis. | 2011 | Details |
| A25281 | 22011249 | DNA Cell Biol | Association of genetic polymorphisms of glutathione-S-transferase genes (GSTT1, GSTM1, and GSTP1) and susceptibility to nonalcoholic fatty liver disease in Zahedan, Southeast Iran. | 2011 | Details |
| A25345 | 21943357 | Nutr Metab (Lond) | The intake of high fat diet with different trans fatty acid levels differentially induces oxidative stress and non alcoholic fatty liver disease (NAFLD) in rats. | 2011 | Details |
| A25449 | 21821020 | Exp Mol Pathol | Liver mitochondrial function and redox status in an experimental model of non-alcoholic fatty liver disease induced by monosodium L-glutamate in rats. | 2011 | Details |
| A25510 | 21755261 | Braz J Med Biol Res | Effect of silybin on high-fat-induced fatty liver in rats. | 2011 | Details |
| A25587 | 21684478 | Arab J Gastroenterol | Paraoxonase-1 activity, malondialdehyde and glutathione peroxidase in non-alcoholic fatty liver disease and the effect of atorvastatin. | 2011 | Details |
| A25606 | 21656912 | Proteomics Clin Appl | Utility of formalin-fixed, paraffin-embedded liver biopsy specimens for global proteomic analysis in nonalcoholic steatohepatitis. | 2011 | Details |
| A25611 | 21649732 | J Gastroenterol Hepatol | Susceptibility of rat non-alcoholic fatty liver to the acute toxic effect of acetaminophen. | 2012 | Details |
| A25634 | 21620948 | Toxicol In Vitro | Cellular glutathione in fatty liver in vitro models. | 2011 | Details |
| A25657 | 21570964 | Exp Mol Pathol | A novel cystine based antioxidant attenuates oxidative stress and hepatic steatosis in diet-induced obese mice. | 2011 | Details |
| A25673 | 21561340 | Metab Syndr Relat Disord | Oxidative stress is activated by free fatty acids in cultured human hepatocytes. | 2011 | Details |
| A25683 | 21549113 | Eur J Pharmacol | Pentoxifylline and melatonin in combination with pioglitazone ameliorate experimental non-alcoholic fatty liver disease. | 2011 | Details |
| A25740 | 21489294 | Lipids Health Dis | Protective effect of whey proteins against nonalcoholic fatty liver in rats. | 2011 | Details |
| A25800 | 21446920 | Clin Sci (Lond) | Methionine and protein metabolism in non-alcoholic steatohepatitis: evidence for lower rate of transmethylation of methionine. | 2011 | Details |
| A25816 | 21429837 | Clin Res Hepatol Gastroenterol | Lack of association of GSTT1 and GSTP1 genes methylation and their expression profiles with risk of NAFLD in a sample of Iranian patients. | 2011 | Details |
| A25839 | 21410800 | Int J Exp Pathol | Is rat liver affected by non-alcoholic steatosis more susceptible to the acute toxic effect of thioacetamide? | 2011 | Details |
| A25911 | 21334394 | J Hepatol | Serum metabolomics reveals γ-glutamyl dipeptides as biomarkers for discrimination among different forms of liver disease. | 2011 | Details |
| A25980 | 21240660 | Obes Surg | Hepatic expression of adiponectin receptors increases with non-alcoholic fatty liver disease progression in morbid obesity in correlation with glutathione peroxidase 1. | 2011 | Details |
| A25997 | 21225151 | Arq Gastroenterol | Experimental induction of steatosis in different tissues after the ingestion of a carbohydrate-rich diet: effect on the liver, on the heart and on indicators of oxidation. | 2011 | Details |
| A26011 | 21206006 | Dis Markers | Association of hypoadiponectinemia with hypoglutathionemia in NAFLD subjects with and without type 2 diabetes. | 2010 | Details |
| A26094 | 21114362 | Physiol Res | The effect of rat strain, diet composition and feeding period on the development of a nutritional model of non-alcoholic fatty liver disease in rats. | 2010 | Details |
| A26199 | 20923528 | J Diabetes | Genistein improves liver function and attenuates non-alcoholic fatty liver disease in a rat model of insulin resistance. | 2009 | Details |
| A26271 | 20805291 | Drug Metab Dispos | Diversity in antioxidant response enzymes in progressive stages of human nonalcoholic fatty liver disease. | 2010 | Details |
| A26309 | 20664958 | Int J Mol Med | Selective aldosterone blocker ameliorates the progression of non-alcoholic steatohepatitis in rats. | 2010 | Details |
| A26318 | 20655714 | J Nutr Biochem | Green tea extract attenuates hepatic steatosis by decreasing adipose lipogenesis and enhancing hepatic antioxidant defenses in ob/ob mice. | 2010 | Details |
| A26360 | 20594230 | J Gastroenterol Hepatol | Oxidative stress and regulation of anti-oxidant enzymes in cytochrome P4502E1 transgenic mouse model of non-alcoholic fatty liver. | 2010 | Details |
| A26388 | 20548286 | Lab Invest | Attenuated progression of diet-induced steatohepatitis in glutathione-deficient mice. | 2010 | Details |
| A26411 | 20501438 | Am J Physiol Gastrointest Liver Physiol | Chronic oxidative stress sensitizes hepatocytes to death from 4-hydroxynonenal by JNK/c-Jun overactivation. | 2009 | Details |
| A26430 | 20471811 | Exp Toxicol Pathol | Anti-apoptotic and anti-inflammatory effects of Silybum marianum in treatment of experimental steatohepatitis. | 2010 | Details |
| A26472 | 20423748 | Metabolism | Plasma metabolomic profile in nonalcoholic fatty liver disease. | 2010 | Details |
| A26486 | 20406065 | Biomark Med | Is alanine aminotransferase level a surrogate biomarker of hepatic apoptosis in nonalcoholic fatty liver disease? | 2010 | Details |
| A26488 | 20402835 | J Dig Dis | Dynamic expression of hepatic thioredoxin mRNA in rats with non-alcoholic fatty liver disease. | 2010 | Details |
| A26493 | 20398645 | Clin Biochem | Oxidative stress is independently associated with non-alcoholic fatty liver disease (NAFLD) in subjects with and without type 2 diabetes. | 2010 | Details |
| A26533 | 20347174 | J Hepatol | Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model. | 2010 | Details |
| A26537 | 20303728 | J Nutr Biochem | Integrated hepatic transcriptome and proteome analysis of mice with high-fat diet-induced nonalcoholic fatty liver disease. | 2010 | Details |
| A26553 | 20216561 | Eur J Clin Nutr | Dietary and physical activity patterns in children with fatty liver. | 2010 | Details |
| A26556 | 20210788 | Basic Clin Pharmacol Toxicol | Hepatic effects of rosiglitazone in rats with the metabolic syndrome. | 2010 | Details |
| A26572 | 20188144 | Biochim Biophys Acta | Selenium supplementation attenuates procollagen-1 and interleukin-8 production in fat-loaded human C3A hepatoblastoma cells treated with TGFbeta1. | 2010 | Details |
| A26598 | 20119733 | Obes Surg | Hepatic gene expression of Caucasian and African-American patients with obesity-related non-alcoholic fatty liver disease. | 2010 | Details |
| A26713 | 19914374 | Free Radic Biol Med | Loss of Nrf2 markedly exacerbates nonalcoholic steatohepatitis. | 2009 | Details |
| A26743 | 19851063 | Ann Nutr Metab | Relation between body fat and liver fat accumulation and cytokine pattern in non-alcoholic patients with chronic HCV infection. | 2009 | Details |
| A26772 | 19817962 | J Gastroenterol Hepatol | Association of polymorphisms of glutamate-cystein ligase and microsomal triglyceride transfer protein genes in non-alcoholic fatty liver disease. | 2009 | Details |
| A26801 | 19756959 | Mol Cell Biochem | Increased liver oxidative stress and altered PUFA metabolism precede development of non-alcoholic steatohepatitis in SREBP-1a transgenic spontaneously hypertensive rats with genetic predisposition to hepatic steatosis. | 2009 | Details |
| A26870 | 19609863 | Histol Histopathol | Voluntary oral feeding of rats not requiring a very high fat diet is a clinically relevant animal model of non-alcoholic fatty liver disease (NAFLD). | 2009 | Details |
| A26902 | 19562447 | Surg Today | Effects of N-acetylcysteine on regeneration following partial hepatectomy in rats with nonalcoholic fatty liver disease. | 2009 | Details |
| A26953 | 19473430 | Hepatol Res | The effect of ursodeoxycholic acid on liver regeneration after partial hepatectomy in rats with non-alcoholic fatty liver disease. | 2009 | Details |
| A27012 | 19358839 | Eur J Pharmacol | Experimental non-alcoholic fatty liver disease results in decreased hepatic uptake transporter expression and function in rats. | 2009 | Details |
| A27165 | 19056644 | J Nutr | Impaired sulfur-amino acid metabolism and oxidative stress in nonalcoholic fatty liver are alleviated by betaine supplementation in rats. | 2008 | Details |
| A27234 | 18938777 | Scand J Gastroenterol | Blood oxidative stress markers in non-alcoholic steatohepatitis and how it correlates with diet. | 2008 | Details |
| A27273 | 18782455 | BMC Gastroenterol | Resveratrol inhibits nonalcoholic fatty liver disease in rats. | 2008 | Details |
| A27346 | 18609067 | Scand J Clin Lab Invest | Evaluation of blood oxidative stress-related parameters in alcoholic liver disease and non-alcoholic fatty liver disease. | 2008 | Details |
| A27388 | 18492019 | Liver Int | Association between combinations of glutathione-S-transferase M1, T1 and P1 genotypes and non-alcoholic fatty liver disease. | 2008 | Details |
| A27481 | 18308829 | Gut | Uncoupling protein-2 (UCP2) induces mitochondrial proton leak and increases susceptibility of non-alcoholic steatohepatitis (NASH) liver to ischaemia-reperfusion injury. | 2008 | Details |
| A27486 | 18299981 | Dig Dis Sci | The transition from fatty liver to NASH associates with SAMe depletion in db/db mice fed a methionine choline-deficient diet. | 2008 | Details |
| A27680 | 17683497 | J Gastroenterol Hepatol | Epigallocatechin gallate attenuates experimental non-alcoholic steatohepatitis induced by high fat diet. | 2007 | Details |
| A27681 | 17683488 | J Gastroenterol Hepatol | Protein glutathionylation increases in the liver of patients with non-alcoholic fatty liver disease. | 2007 | Details |
| A27684 | 17671740 | Int J Mol Med | Re-evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease. | 2007 | Details |
| A27695 | 17654601 | Hepatology | Effects of rosiglitazone on the liver histology and mitochondrial function in ob/ob mice. | 2007 | Details |
| A27699 | 17640958 | Drug Metab Dispos | Efflux transporter expression and acetaminophen metabolite excretion are altered in rodent models of nonalcoholic fatty liver disease. | 2007 | Details |
| A27767 | 17487136 | J Med Assoc Thai | Effects of N-acetylcysteine on oxidative stress in rats with non-alcoholic steatohepatitis. | 2007 | Details |
| A27933 | 16958667 | J Gastroenterol Hepatol | Mitochondrial glutathione: hepatocellular survival-death switch. | 2006 | Details |
| A27945 | 16935387 | J Hepatol | Hepatic gene expression profile associated with non-alcoholic steatohepatitis protection by S-nitroso-N-acetylcysteine in ob/ob mice. | 2006 | Details |
| A27969 | 16842545 | J Pineal Res | Melatonin ameliorates nonalcoholic fatty liver induced by high-fat diet in rats. | 2006 | Details |
| A28006 | 16762007 | Liver Int | Fenofibrate, a peroxisome proliferator-activated receptor alpha agonist, reduces hepatic steatosis and lipid peroxidation in fatty liver Shionogi mice with hereditary fatty liver. | 2006 | Details |
| A28068 | 16531961 | Ann Hepatol | Pentoxifylline does not prevent neither liver damage nor early profibrogenic events in a rat model of non-alcoholic steatohepatitis. | 2006 | Details |
| A28109 | 16398154 | Orv Hetil | [The therapeutic effect of metadoxine on alcoholic and non-alcoholic steatohepatitis]. | 2005 | Details |
| A28113 | 16393285 | Aliment Pharmacol Ther | Blood oxidative stress markers are unreliable markers of hepatic steatosis. | 2006 | Details |
| A28154 | 16252194 | Turk J Gastroenterol | Assessment of lipid peroxidation and antioxidant capacity in non-alcoholic fatty liver disease. | 2005 | Details |
| A28201 | 16162151 | Liver Int | Increase in liver antioxidant enzyme activities in non-alcoholic fatty liver disease. | 2005 | Details |
| A28209 | 16139386 | J Hepatol | Characterization of organic anion transporter regulation, glutathione metabolism and bile formation in the obese Zucker rat. | 2005 | Details |
| A28268 | 15887119 | Gastroenterology | Mice heterozygous for a defect in mitochondrial trifunctional protein develop hepatic steatosis and insulin resistance. | 2005 | Details |
| A28293 | 15763346 | J Hepatol | Heme oxygenase-1 levels and oxidative stress-related parameters in non-alcoholic fatty liver disease patients. | 2005 | Details |
| A28348 | 15554233 | Drug Metab Rev | The discovery of the microsomal ethanol oxidizing system and its physiologic and pathologic role. | 2004 | Details |
| A28350 | 15542525 | Gut | Bile secretory function in the obese Zucker rat: evidence of cholestasis and altered canalicular transport function. | 2004 | Details |
| A28351 | 15522905 | FASEB J | A high-fat diet leads to the progression of non-alcoholic fatty liver disease in obese rats. | 2004 | Details |
| A28365 | 15464239 | J Hepatol | Pentoxifylline attenuates steatohepatitis induced by the methionine choline deficient diet. | 2004 | Details |
| A28430 | 15013444 | Biochem Biophys Res Commun | Pioglitazone prevents hepatic steatosis, fibrosis, and enzyme-altered lesions in rat liver cirrhosis induced by a choline-deficient L-amino acid-defined diet. | 2004 | Details |
| A28464 | 14556645 | Clin Sci (Lond) | Oxidative stress-related parameters in the liver of non-alcoholic fatty liver disease patients. | 2004 | Details |
| A28472 | 12908728 | Eur Rev Med Pharmacol Sci | Experimental observations and clinical implications of fasting and diet supplementation in fatty livers. | 2003 | Details |
| A28743 | 35074674 | Spectrochim Acta A Mol Biomol Spectrosc | Gold as a coordinator of an imidazole conjugated dye of BODIPY derivatives for the identification of simple mercaptans. | 2022 | Details |
| A28972 | 34760013 | Res Pharm Sci | Attenuating effects of allantoin on oxidative stress in a mouse model of nonalcoholic steatohepatitis: role of SIRT1/Nrf2 pathway. | 2021 | Details |
| A29659 | 33729641 | J Biochem Mol Toxicol | Differentially expressed proteins obtained by label-free quantitative proteomic analysis reveal affected biological processes and functions in Western diet-induced steatohepatitis. | 2021 | Details |
| A30167 | 32875282 | JHEP Rep | Transcriptomic analysis across liver diseases reveals disease-modulating activation of constitutive androstane receptor in cholestasis. | 2020 | Details |
| A30204 | 32821335 | World J Hepatol | Anti-inflammatory and anti-oxidant effects of aloe vera in rats with non-alcoholic steatohepatitis. | 2020 | Details |
| A30564 | 32205234 | Pharmacol Res | Obesity and NRF2-mediated cytoprotection: Where is the missing link? | 2020 | Details |
| A30606 | 32121273 | Int J Mol Sci | Reclassifying Hepatic Cell Death during Liver Damage: Ferroptosis-A Novel Form of Non-Apoptotic Cell Death? | 2020 | Details |
| A31279 | 30907226 | Autophagy | Dual roles of ULK1 (unc-51 like autophagy activating kinase 1) in cytoprotection against lipotoxicity. | 2019 | Details |
| A31388 | 30669672 | Molecules | Design and Synthesis of a Fluorescent Probe with a Large Stokes Shift for Detecting Thiophenols and Its Application in Water Samples and Living Cells. | 2019 | Details |
| A31681 | 30050648 | Oxid Med Cell Longev | Double Knockout of Peroxiredoxin 4 (Prdx4) and Superoxide Dismutase 1 (Sod1) in Mice Results in Severe Liver Failure. | 2018 | Details |