Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
stats1
stats2
stats3
stats4
Search for:
Lipid metabolism4743 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A03225 | 34081362 | J Intern Med | Pulmonary hypertension is associated with an increased incidence of NAFLD: A retrospective cohort study of 18,910 patients. | 2021 | Details |
| A03245 | 34073834 | Int J Mol Sci | P2Y2R Deficiency Ameliorates Hepatic Steatosis by Reducing Lipogenesis and Enhancing Fatty Acid β-Oxidation through AMPK and PGC-1α Induction in High-Fat Diet-Fed Mice. | 2021 | Details |
| A03247 | 34072832 | Cells | Epigenetic Regulation of Peroxisome Proliferator-Activated Receptor Gamma Mediates High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A03248 | 34072586 | Int J Mol Sci | One Week of CDAHFD Induces Steatohepatitis and Mitochondrial Dysfunction with Oxidative Stress in Liver. | 2021 | Details |
| A03251 | 34070938 | Int J Mol Sci | Magnesium Isoglycyrrhizinate Reduces Hepatic Lipotoxicity through Regulating Metabolic Abnormalities. | 2021 | Details |
| A03253 | 34069635 | Nutrients | Exploratory Data Analysis of Cell and Mitochondrial High-Fat, High-Sugar Toxicity on Human HepG2 Cells. | 2021 | Details |
| A03255 | 34069390 | Cells | Maternal Exercise Mediates Hepatic Metabolic Programming via Activation of AMPK-PGC1α Axis in the Offspring of Obese Mothers. | 2021 | Details |
| A03260 | 34067931 | Int J Mol Sci | Understanding the Role of Perilipin 5 in Non-Alcoholic Fatty Liver Disease and Its Role in Hepatocellular Carcinoma: A Review of Novel Insights. | 2021 | Details |
| A03267 | 34065270 | Nutrients | Comparison of the Improvement Effect of Deep Ocean Water with Different Mineral Composition on the High Fat Diet-Induced Blood Lipid and Nonalcoholic Fatty Liver Disease in a Mouse Model. | 2021 | Details |
| A03279 | 34063472 | Int J Mol Sci | The Potential Protective Role of RUNX1 in Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03280 | 34062716 | Int J Mol Sci | Role of Endocrine-Disrupting Chemicals in the Pathogenesis of Non-Alcoholic Fatty Liver Disease: A Comprehensive Review. | 2021 | Details |
| A03282 | 34062416 | Biomed Pharmacother | The HIF-2α/PPARα pathway is essential for liraglutide-alleviated, lipid-induced hepatic steatosis. | 2021 | Details |
| A03285 | 34060951 | Endocr Res | AST-120 Treatment Alters the Gut Microbiota Composition and Suppresses Hepatic Triglyceride Levels in Obese Mice. | 2021 | Details |
| A03287 | 34060475 | J Endocrinol | DHT causes liver steatosis via transcriptional regulation of SCAP in normal weight female mice. | 2021 | Details |
| A03291 | 34058224 | Metabolism | Regulation of hepatic fibrosis by carcinoembryonic antigen-related cell adhesion molecule 1. | 2021 | Details |
| A03293 | 34058074 | FEBS J | Role of Mcpip1 in obesity-induced hepatic steatosis as determined by myeloid and liver-specific conditional knockouts. | 2021 | Details |
| A03301 | 34052855 | Diabetologia | Non-alcoholic fatty liver disease in mice with hepatocyte-specific deletion of mitochondrial fission factor. | 2021 | Details |
| A03302 | 34052187 | Biochem Pharmacol | Upregulation of miR-96-5p by bone marrow mesenchymal stem cells and their exosomes alleviate non-alcoholic steatohepatitis: Emphasis on caspase-2 signaling inhibition. | 2021 | Details |
| A03316 | 34048566 | J Mol Cell Biol | PSA controls hepatic lipid metabolism by regulating the NRF2 signaling pathway. | 2021 | Details |
| A03322 | 34046014 | Front Endocrinol (Lausanne) | Spinal Cord Injury Reduces Serum Levels of Fibroblast Growth Factor-21 and Impairs Its Signaling Pathways in Liver and Adipose Tissue in Mice. | 2021 | Details |
| A03333 | 34040411 | J Inflamm Res | Ginkgo biloba Extract 50 (GBE50) Ameliorates Insulin Resistance, Hepatic Steatosis and Liver Injury in High Fat Diet-Fed Mice. | 2021 | Details |
| A03338 | 34036256 | JHEP Rep | A human liver chimeric mouse model for non-alcoholic fatty liver disease. | 2021 | Details |
| A03341 | 34034750 | Lipids Health Dis | Circulating angiopoietin-like proteins in metabolic-associated fatty liver disease: a systematic review and meta-analysis. | 2021 | Details |
| A03348 | 34032730 | Medicine (Baltimore) | Acupuncture for type 2 diabetes mellitus with nonalcoholic fatty liver disease: A protocol for systematic review and meta-analysis. | 2021 | Details |
| A03351 | 34031913 | J Gastroenterol Hepatol | TA allele of rs2070673 in the CYP2E1 gene is associated with lobular inflammation and nonalcoholic steatohepatitis in patients with biopsy-proven nonalcoholic fatty liver disease. | 2021 | Details |
| A03353 | 34031390 | Nat Commun | PPDPF alleviates hepatic steatosis through inhibition of mTOR signaling. | 2021 | Details |
| A03358 | 34029162 | Am J Physiol Endocrinol Metab | β2-Adrenergic receptor agonist induced hepatic steatosis in mice: modeling nonalcoholic fatty liver disease in hyperadrenergic states. | 2021 | Details |
| A03363 | 34027561 | Arch Toxicol | Infections at the nexus of metabolic-associated fatty liver disease. | 2021 | Details |
| A03370 | 34027265 | Hepatol Commun | Impact of Sodium Glucose Cotransporter 2 Inhibitors on Nonalcoholic Fatty Liver Disease Complicated by Diabetes Mellitus. | 2021 | Details |
| A03384 | 34022528 | Bioorg Med Chem | Discovery of novel modulators for the PPARα (peroxisome proliferator activated receptor α): Potential therapies for nonalcoholic fatty liver disease. | 2021 | Details |
| A03393 | 34017413 | Am J Transl Res | Correlation of CD3+/CD4+, and serum CK-18 fragment levels with glucose and lipid metabolism in elderly type 2 diabetes patients with nonalcoholic fatty liver disease. | 2021 | Details |
| A03403 | 34014450 | Hepatol Int | Hepatic stellate cells-specific LOXL1 deficiency abrogates hepatic inflammation, fibrosis, and corrects lipid metabolic abnormalities in non-obese NASH mice. | 2021 | Details |
| A03413 | 34010603 | Exp Eye Res | The role of peroxisome proliferator-activated receptors in healthy and diseased eyes. | 2021 | Details |
| A03418 | 34007294 | Evid Based Complement Alternat Med | Mechanism of Huo-Xue-Qu-Yu Formula in Treating Nonalcoholic Hepatic Steatosis by Regulating Lipid Metabolism and Oxidative Stress in Rats. | 2021 | Details |
| A03424 | 34004342 | J Nutr Biochem | Saskatoon berry powder reduces hepatic steatosis and insulin resistance in high fat-high sucrose diet-induced obese mice. | 2021 | Details |
| A03427 | 34003729 | Am J Respir Cell Mol Biol | Hepatocyte HIF-1 and Intermittent Hypoxia Independently Impact Liver Fibrosis in Murine Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03430 | 34002452 | Obes Rev | Bariatric surgery and the liver-Mechanisms, benefits, and risks. | 2021 | Details |
| A03439 | 34000413 | J Nutr Biochem | PAR2 promotes high-fat diet-induced hepatic steatosis by inhibiting AMPK-mediated autophagy. | 2021 | Details |
| A03442 | 33998431 | J Dev Orig Health Dis | Pregnancy and lactation after Roux-en-Y gastric bypass worsen nonalcoholic fatty liver disease in obese rats and lead to differential programming of hepatic de novo lipogenesis in offspring. | 2021 | Details |
| A03447 | 33995543 | Evid Based Complement Alternat Med | Network Pharmacology-Based Investigation of the Therapeutic Mechanisms of Action of Danning Tablets in Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03452 | 33994867 | Int J Biol Sci | MicroRNAs in the Pathogenesis of Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03453 | 33994854 | Int J Biol Sci | Berberine alleviates lipid metabolism disorders via inhibition of mitochondrial complex I in gut and liver. | 2021 | Details |
| A03463 | 33992352 | Food Res Int | Caffeic acid prevents non-alcoholic fatty liver disease induced by a high-fat diet through gut microbiota modulation in mice. | 2021 | Details |
| A03466 | 33991837 | Bioorg Chem | Anti-inflammatory effect of luteolin is related to the changes in the gut microbiota and contributes to preventing the progression from simple steatosis to nonalcoholic steatohepatitis. | 2021 | Details |
| A03468 | 33991615 | Cell Signal | Secretory Galectin-3 promotes hepatic steatosis via regulation of the PPARγ/CD36 signaling pathway. | 2021 | Details |
| A03476 | 33989817 | Cell Mol Gastroenterol Hepatol | Sodium Butyrate Supplementation Inhibits Hepatic Steatosis by Stimulating Liver Kinase B1 and Insulin-Induced Gene. | 2021 | Details |
| A03478 | 33989548 | Cell | Mechanisms and disease consequences of nonalcoholic fatty liver disease. | 2021 | Details |
| A03487 | 33987020 | PeerJ | Serum metabolomic profiling reveals an increase in homocitrulline in Chinese patients with nonalcoholic fatty liver disease: a retrospective study. | 2021 | Details |
| A03492 | 33984335 | Metabolism | Fenofibrate, a PPARα agonist, reduces hepatic fat accumulation through the upregulation of TFEB-mediated lipophagy. | 2021 | Details |
| A03501 | 33980978 | Commun Biol | Sterol O-acyltransferase 2 chaperoned by apolipoprotein J facilitates hepatic lipid accumulation following viral and nutrient stresses. | 2021 | Details |
| A03507 | 33977953 | Food Funct | Hesperetin ameliorates hepatic oxidative stress and inflammation via the PI3K/AKT-Nrf2-ARE pathway in oleic acid-induced HepG2 cells and a rat model of high-fat diet-induced NAFLD. | 2021 | Details |
| A03508 | 33977946 | Food Funct | DHA-enriched phosphatidylserine ameliorates non-alcoholic fatty liver disease and intestinal dysbacteriosis in mice induced by a high-fat diet. | 2021 | Details |
| A03520 | 33972568 | Sci Rep | Allopurinol ameliorates high fructose diet induced hepatic steatosis in diabetic rats through modulation of lipid metabolism, inflammation, and ER stress pathway. | 2021 | Details |
| A03528 | 33967606 | Int J Med Sci | H. pylori is related to NAFLD but only in female: A Cross-sectional Study. | 2021 | Details |
| A03535 | 33965533 | J Nutr Biochem | Toll-like receptor 3 ablation prevented high-fat diet-induced obesity and metabolic disorder. | 2021 | Details |
| A03551 | 33960342 | Food Funct | Functional milk fat enriched in conjugated linoleic acid prevented liver lipid accumulation induced by a high-fat diet in male rats. | 2021 | Details |
| A03554 | 33957975 | BMC Res Notes | Association of 45-bp ins/del polymorphism of uncoupling protein 2 (UCP2) and susceptibility to nonalcoholic fatty liver and type 2 diabetes mellitus in North-west of Iran. | 2021 | Details |
| A03558 | 33955510 | Mol Med Rep | Parthenolide plays a protective role in the liver of mice with metabolic dysfunction‑associated fatty liver disease through the activation of the HIPPO pathway. | 2021 | Details |
| A03562 | 33953586 | Diabetes Metab Syndr Obes | Astragaloside IV Alleviates Liver Inflammation, Oxidative Stress and Apoptosis to Protect Against Experimental Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A03566 | 33952255 | Lipids Health Dis | Screening for the presence of scleroedema adultorum of Buschke in patients with diabetes mellitus: newly diagnosed patients had a high prevalence of dyslipidaemia. | 2021 | Details |
| A03572 | 33948987 | FASEB J | Porphyran-derived oligosaccharides alleviate NAFLD and related cecal microbiota dysbiosis in mice. | 2021 | Details |
| A03590 | 33939383 | Clin Transl Gastroenterol | Moderate-Intensity Aerobic vs Resistance Exercise and Dietary Modification in Patients With Nonalcoholic Fatty Liver Disease: A Randomized Clinical Trial. | 2021 | Details |
| A03595 | 33938212 | Environ Sci Technol | Nonalcoholic Fatty Liver Disease Development in Zebrafish upon Exposure to Bis(2-ethylhexyl)-2,3,4,5-tetrabromophthalate, a Novel Brominated Flame Retardant. | 2021 | Details |
| A03600 | 33937257 | Front Cell Dev Biol | Autophagy in Hepatic Steatosis: A Structured Review. | 2021 | Details |
| A03604 | 33935282 | Int J Obes (Lond) | The effect of physical activity level and exercise training on the association between plasma branched-chain amino acids and intrahepatic lipid content in participants with obesity. | 2021 | Details |
| A03628 | 33925122 | Curr Issues Mol Biol | Effect of Bombyx mori on the Liver Protection of Non-Alcoholic Fatty Liver Disease Based on In Vitro and In Vivo Models. | 2021 | Details |
| A03632 | 33924115 | Int J Mol Sci | Chronic High Fat Diet Intake Impairs Hepatic Metabolic Parameters in Ovariectomized Sirt3 KO Mice. | 2021 | Details |
| A03633 | 33923817 | Int J Mol Sci | Role of Insulin Resistance in MAFLD. | 2021 | Details |
| A03635 | 33923525 | Nutrients | The Role of Fructose in Non-Alcoholic Steatohepatitis: Old Relationship and New Insights. | 2021 | Details |
| A03639 | 33923175 | Cells | Adipocyte, Immune Cells, and miRNA Crosstalk: A Novel Regulator of Metabolic Dysfunction and Obesity. | 2021 | Details |
| A03640 | 33923083 | Cells | Integrated Action of Autophagy and Adipose Tissue Triglyceride Lipase Ameliorates Diet-Induced Hepatic Steatosis in Liver-Specific PLIN2 Knockout Mice. | 2021 | Details |
| A03653 | 33918878 | Int J Mol Sci | Nonalcoholic Fatty Liver Disease: Focus on New Biomarkers and Lifestyle Interventions. | 2021 | Details |
| A03657 | 33917919 | Cancers (Basel) | The rs599839 A>G Variant Disentangles Cardiovascular Risk and Hepatocellular Carcinoma in NAFLD Patients. | 2021 | Details |
| A03663 | 33916843 | Antioxidants (Basel) | Cisd2 Protects the Liver from Oxidative Stress and Ameliorates Western Diet-Induced Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03677 | 33907839 | Int J Mol Med | Role of 2‑series prostaglandins in the pathogenesis of type 2 diabetes mellitus and non‑alcoholic fatty liver disease (Review). | 2021 | Details |
| A03682 | 33903707 | Sci Rep | MicroRNA Let-7 targets AMPK and impairs hepatic lipid metabolism in offspring of maternal obese pregnancies. | 2021 | Details |
| A03683 | 33903148 | Gut | Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target. | 2021 | Details |
| A03693 | 33900847 | Am J Physiol Endocrinol Metab | High uric acid induces liver fat accumulation via ROS/JNK/AP-1 signaling. | 2021 | Details |
| A03704 | 33897616 | Front Endocrinol (Lausanne) | Glucagon-Like Peptide-1 Receptor Agonists for Non-Alcoholic Fatty Liver Disease in Type 2 Diabetes: A Meta-Analysis. | 2021 | Details |
| A03710 | 33895552 | Biochem Biophys Res Commun | The PDE5 inhibitor udenafil ameliorates nonalcoholic fatty liver disease by improving mitochondrial function. | 2021 | Details |
| A03713 | 33895138 | J Biol Chem | Loss of Down syndrome critical region-1 leads to cholesterol metabolic dysfunction that exaggerates hypercholesterolemia in ApoE-null background. | 2021 | Details |
| A03715 | 33894178 | Am J Pathol | Inhibition of Estrogen-Related Receptor α Blocks Liver Steatosis and Steatohepatitis and Attenuates Triglyceride Biosynthesis. | 2021 | Details |
| A03722 | 33892169 | Mol Metab | Metabolic-associated fatty liver disease and lipoprotein metabolism. | 2021 | Details |
| A03729 | 33887577 | Int Immunopharmacol | Neutrophil: An emerging player in the occurrence and progression of metabolic associated fatty liver disease. | 2021 | Details |
| A03730 | 33887358 | J Hepatol | Hepatic lipidomic remodeling in severe obesity manifests with steatosis and does not evolve with non-alcoholic steatohepatitis. | 2021 | Details |
| A03732 | 33885128 | Food Funct | Modulation of the fecal microbiome and metabolome by resistant dextrin ameliorates hepatic steatosis and mitochondrial abnormalities in mice. | 2021 | Details |
| A03744 | 33879971 | J Clin Biochem Nutr | Vitamin B6 efficacy in the treatment of nonalcoholic fatty liver disease: an open-label, single-arm, single-center trial. | 2021 | Details |
| A03753 | 33877366 | Diabetologia | Liver-targeting drugs and their effect on blood glucose and hepatic lipids. | 2021 | Details |
| A03757 | 33873073 | J Pharm Biomed Anal | Investigation of the therapeutic effect of Yinchen Wuling Powder on CCl4-induced hepatic fibrosis in rats by 1H NMR and MS-based metabolomics analysis. | 2021 | Details |
| A03763 | 33871418 | Curr Opin Clin Nutr Metab Care | Beyond weight loss in nonalcoholic fatty liver disease: the role of carbohydrate restriction. | 2021 | Details |
| A03770 | 33869312 | Front Cardiovasc Med | The Roles and Pharmacological Effects of FGF21 in Preventing Aging-Associated Metabolic Diseases. | 2021 | Details |
| A03778 | 33867326 | Pak J Pharm Sci | Effects of shikonin from Zicao on high-fat diet-induced nonalcoholic fatty liver disease in rats. | 2020 | Details |
| A03782 | 33865898 | Metabolism | Collagen β(1-O) galactosyltransferase 2 deficiency contributes to lipodystrophy and aggravates NAFLD related to HMW adiponectin in mice. | 2021 | Details |
| A03793 | 33862107 | Life Sci | Naringin improves lipid metabolism in a tissue-engineered liver model of NAFLD and the underlying mechanisms. | 2021 | Details |
| A03801 | 33860590 | Phytother Res | Administration of isoliquiritigenin prevents nonalcoholic fatty liver disease through a novel IQGAP2-CREB-SIRT1 axis. | 2021 | Details |
| A03803 | 33860199 | ACS Pharmacol Transl Sci | Peripherally Selective CB1 Receptor Antagonist Improves Symptoms of Metabolic Syndrome in Mice. | 2021 | Details |
| A03815 | 33859314 | Sci Rep | Extra virgin olive oil improved body weight and insulin sensitivity in high fat diet-induced obese LDLr-/-.Leiden mice without attenuation of steatohepatitis. | 2021 | Details |
| A03817 | 33857709 | Environ Int | Effects of environmental contaminants in water resources on nonalcoholic fatty liver disease. | 2021 | Details |
| A03818 | 33857628 | Free Radic Biol Med | Hepatocyte-specific deletion of Nlrp6 in mice exacerbates the development of non-alcoholic steatohepatitis. | 2021 | Details |
| A03820 | 33857511 | Int J Biol Macromol | Walnut green husk polysaccharides prevent obesity, chronic inflammatory responses, nonalcoholic fatty liver disease and colonic tissue damage in high-fat diet fed rats. | 2021 | Details |