Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A46253 | 19967814 | Eksp Klin Gastroenterol | [The evolution of ideas about nonalcohol fatty liver disease]. | 2009 | Details |
| A46256 | 19958654 | Zhonghua Gan Zang Bing Za Zhi | [Therapeutic effects of compound glycyrrhizin liposome on fibrosis of the rats with nonalcoholic steatohepatitis]. | 2009 | Details |
| A46259 | 19949375 | Lab Invest | Reversibility of fibrosis, inflammation, and endoplasmic reticulum stress in the liver of rats fed a methionine-choline-deficient diet. | 2009 | Details |
| A46267 | 19918973 | Hepatology | Lack of interleukin-6/glycoprotein 130/signal transducers and activators of transcription-3 signaling in hepatocytes predisposes to liver steatosis and injury in mice. | 2010 | Details |
| A46289 | 19763702 | J Gastrointest Surg | Downregulation of adiponectin/AdipoR2 is associated with steatohepatitis in obese mice. | 2009 | Details |
| A46292 | 19739236 | Hepatology | Chronically inflamed livers up-regulate expression of inhibitory B7 family members. | 2009 | Details |
| A46323 | 19549522 | Gastroenterology | c-Jun N-terminal kinase-1 from hematopoietic cells mediates progression from hepatic steatosis to steatohepatitis and fibrosis in mice. | 2009 | Details |
| A46325 | 19541924 | Am J Physiol Gastrointest Liver Physiol | Trans fat feeding results in higher serum alanine aminotransferase and increased insulin resistance compared with a standard murine high-fat diet. | 2009 | Details |
| A46328 | 19506316 | ILAR J | Metabolic consequences of sleep-disordered breathing. | 2009 | Details |
| A46329 | 19502655 | Ann Hepatol | Adipokines in a group of Mexican patients with nonalcoholic steatohepatitis. | 2009 | Details |
| A46342 | 19440711 | Semin Immunopathol | The immunopathogenesis of alcoholic and nonalcoholic steatohepatitis: two triggers for one disease? | 2009 | Details |
| A46344 | 19404203 | Eur J Gastroenterol Hepatol | Hepatocellular adenoma in advanced-stage fatty liver disease. | 2009 | Details |
| A46348 | 19387919 | Semin Liver Dis | Similarities and differences in the pathogenesis of alcoholic and nonalcoholic steatohepatitis. | 2009 | Details |
| A46354 | 19346774 | Nestle Nutr Workshop Ser Pediatr Program | Obesity, inflammation, and macrophages. | 2009 | Details |
| A46369 | 19262374 | Curr Opin Endocrinol Diabetes Obes | Nonalcoholic fatty liver disease in type 2 diabetes mellitus. | 2009 | Details |
| A46386 | 19131468 | Diabetes Care | Synergy between adiposity, insulin resistance, metabolic risk factors, and inflammation in adolescents. | 2009 | Details |
| A46395 | 19062531 | Genetika | [Adipokine genetics: unbalanced protein secretion by human adipose tissue as a cause of the metabolic syndrome]. | 2008 | Details |
| A46398 | 19046821 | Med Hypotheses | Adipose tissue transplantation may be a potential treatment for diabetes, atherosclerosis and nonalcoholic steatohepatitis. | 2008 | Details |
| A46407 | 19027012 | Gastroenterology | Tissue inhibitor of metalloproteinase 3 deficiency causes hepatic steatosis and adipose tissue inflammation in mice. | 2008 | Details |
| A46412 | 18971485 | Endocr Rev | The metabolic syndrome. | 2008 | Details |
| A46415 | 18830789 | Obes Surg | Retinol and alpha-tocopherol in morbid obesity and nonalcoholic fatty liver disease. | 2008 | Details |
| A46418 | 20209757 | Rev Med Chir Soc Med Nat Iasi | [Adipocitokines and nonalcoholic steatohepatitis]. | 2010 | Details |
| A46423 | 18787467 | Eur J Gastroenterol Hepatol | Interleukin-10 to tumor necrosis factor-alpha ratio is a predictive biomarker in nonalcoholic fatty liver disease: interleukin-10 to tumor necrosis factor-alpha ratio in steatohepatitis. | 2008 | Details |
| A46434 | 18676239 | Nan Fang Yi Ke Da Xue Xue Bao | [Effect of a compound Danshen preparation in preventing long-term gastric lipid emulsion administration-induced nonalcoholic steatohepatitis in rats]. | 2008 | Details |
| A46439 | 18666225 | Hepatology | Beyond insulin resistance: Innate immunity in nonalcoholic steatohepatitis. | 2008 | Details |
| A46452 | 18542010 | Curr Opin Clin Nutr Metab Care | Role of dietary carbohydrates and macronutrients in the pathogenesis of nonalcoholic fatty liver disease. | 2008 | Details |
| A46459 | 18460980 | Am J Surg Pathol | Histologic abnormalities are common in protocol liver allograft biopsies from patients with normal liver function tests. | 2008 | Details |
| A46485 | 18356447 | AJR Am J Roentgenol | Nonalcoholic fatty liver disease. | 2008 | Details |
| A46488 | 18345311 | HPB (Oxford) | Nonalcoholic fatty pancreas disease. | 2007 | Details |
| A46500 | 18235842 | Mol Med | Inflammatory mechanisms in the regulation of insulin resistance. | 2008 | Details |
| A46505 | 18203148 | Hepatology | Interferon regulatory factor-3 activation, hepatic interferon-stimulated gene expression, and immune cell infiltration in hepatitis C virus patients. | 2008 | Details |
| A46510 | 30743783 | Expert Rev Endocrinol Metab | Inflammatory biomarkers associated with obesity and insulin resistance: a focus on lipocalin-2 and adipocyte fatty acid-binding protein. | 2008 | Details |
| A46511 | 19472691 | Tunis Med | [Nonalcoholic steatohepatitis: epidemiologic and pathologic study of 9 cases]. | 2008 | Details |
| A46517 | 18054848 | Dig Liver Dis | Effects of n-3 polyunsaturated fatty acids in subjects with nonalcoholic fatty liver disease. | 2007 | Details |
| A46520 | 18046722 | Hepatology | Effects of rosiglitazone on methionine-choline deficient diet-induced nonalcoholic steatohepatitis. | 2007 | Details |
| A46522 | 17979073 | Semin Liver Dis | Endoplasmic reticulum stress and liver injury. | 2007 | Details |
| A46536 | 17720354 | Am J Med | Abdominal adiposity and cardiometabolic risk: do we have all the answers? | 2007 | Details |
| A46547 | 17691941 | Curr Med Chem | Hepatobiliary diseases and insulin resistance. | 2007 | Details |
| A46553 | 17667055 | J Clin Gastroenterol | Medex test, a novel modality for liver disease diagnosis: a pilot study. | 2007 | Details |
| A46555 | 17661402 | Hepatology | A high-fat diet and regulatory T cells influence susceptibility to endotoxin-induced liver injury. | 2007 | Details |
| A46561 | 17578885 | Am J Physiol Endocrinol Metab | Macrophage TNF-alpha contributes to insulin resistance and hepatic steatosis in diet-induced obesity. | 2007 | Details |
| A46576 | 17498510 | Gastroenterology | Obesity, inflammation, and insulin resistance. | 2007 | Details |
| A46597 | 17376209 | Clin Exp Dermatol | Psoriasis treated with ursodeoxycholic acid: three case reports. | 2007 | Details |
| A46603 | 17354303 | N Engl J Med | Pioglitazone in nonalcoholic steatohepatitis. | 2007 | Details |
| A46623 | 17219068 | Dig Dis Sci | The effect of a low-carbohydrate, ketogenic diet on nonalcoholic fatty liver disease: a pilot study. | 2007 | Details |
| A46627 | 17160239 | Arq Gastroenterol | Prevalence of the hemochromatosis gene mutation in patients with nonalcoholic steatohepatitis and correlation with degree of liver fibrosis. | 2007 | Details |
| A46645 | 16932311 | Nat Clin Pract Endocrinol Metab | Mechanisms of Disease: hepatic steatosis in type 2 diabetes--pathogenesis and clinical relevance. | 2006 | Details |
| A46653 | 16844679 | Am J Physiol Gastrointest Liver Physiol | Inhibition of matrix metalloproteinases increases PPAR-alpha and IL-6 and prevents dietary-induced hepatic steatosis and injury in a murine model. | 2006 | Details |
| A46666 | 16762000 | Liver Int | Differential findings for CD14-positive hepatic monocytes/macrophages in primary biliary cirrhosis, chronic hepatitis C and nonalcoholic steatohepatitis. | 2006 | Details |
| A46682 | 16557554 | Hepatology | COX-2 induction in mice with experimental nutritional steatohepatitis: Role as pro-inflammatory mediator. | 2006 | Details |
| A46690 | 16510031 | Curr Gastroenterol Rep | New treatments for nonalcoholic fatty liver disease. | 2006 | Details |
| A46692 | 16489319 | Panminerva Med | Insulin resistance, the insulin resistance syndrome, and cardiovascular disease. | 2005 | Details |
| A46705 | 16361039 | Clin Gastroenterol Hepatol | GIH clinical research update: 2004-2005. | 2005 | Details |
| A46715 | 16265231 | Nat Clin Pract Gastroenterol Hepatol | Mechanisms of disease: adipocytokines and visceral adipose tissue--emerging role in nonalcoholic fatty liver disease. | 2005 | Details |
| A46721 | 16226915 | Hepatol Res | Role of suppressors of cytokine signaling SOCS-1 and SOCS-3 in hepatic steatosis and the metabolic syndrome. | 2005 | Details |
| A46722 | 16220049 | Curr Opin Gastroenterol | Role of inflammation in nonalcoholic steatohepatitis. | 2005 | Details |
| A46725 | 16175608 | Hepatology | Dietary factors alter hepatic innate immune system in mice with nonalcoholic fatty liver disease. | 2005 | Details |
| A46747 | 15976528 | Alcohol Clin Exp Res | Increased lipopolysaccharide sensitivity in alcoholic fatty livers is independent of leptin deficiency and toll-like receptor 4 (TLR4) or TLR2 mRNA expression. | 2005 | Details |
| A46752 | 15913829 | J Hepatol | Signalling links in the liver: knitting SOCS with fat and inflammation. | 2005 | Details |
| A46755 | 15882516 | Med Clin (Barc) | [Pathogenesis of primary nonalcoholic fatty liver disease]. | 2005 | Details |
| A46773 | 15703606 | Curr Opin Gastroenterol | Innate immunity in the liver. | 2003 | Details |
| A46776 | 15670659 | Alcohol | Role of fatty liver, dietary fatty acid supplements, and obesity in the progression of alcoholic liver disease: introduction and summary of the symposium. | 2004 | Details |
| A46777 | 15659701 | Pediatr Res | Omega-3 fatty acid supplementation prevents hepatic steatosis in a murine model of nonalcoholic fatty liver disease. | 2005 | Details |
| A46803 | 15254578 | J Clin Invest | Molecular mediators of hepatic steatosis and liver injury. | 2004 | Details |
| A46804 | 15240880 | Proc Natl Acad Sci U S A | Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse. | 2004 | Details |
| A46816 | 14752843 | Hepatology | Vascular involvement of the liver in Turner's syndrome. | 2004 | Details |
| A46818 | 14720455 | Curr Gastroenterol Rep | New concepts of the pathogenesis of alcoholic liver disease lead to novel treatments. | 2004 | Details |
| A46859 | 12417056 | J Cell Mol Med | Oxidative stress in the pathogenesis of nonalcoholic fatty liver disease, in rats fed with a choline-deficient diet. | 2003 | Details |
| A46903 | 35053298 | Cells | NLRP6 Inflammasome Modulates Disease Progression in a Chronic-Plus-Binge Mouse Model of Alcoholic Liver Disease. | 2022 | Details |
| A46912 | 34525389 | J Nutr Biochem | A mouse model of the regression of alcoholic hepatitis: Monitoring the regression of hepatic steatosis, inflammation, oxidative stress, and NAD+ metabolism upon alcohol withdrawal. | 2021 | Details |
| A46913 | 34523155 | Alcohol Clin Exp Res | A Western diet with alcohol in drinking water recapitulates features of alcohol-associated liver disease in mice. | 2021 | Details |
| A46914 | 34513903 | Front Nutr | The Role of Intestinal Permeability in Gastrointestinal Disorders and Current Methods of Evaluation. | 2021 | Details |
| A46915 | 34428307 | Aliment Pharmacol Ther | Progressive alcohol-related liver fibrosis is characterised by imbalanced collagen formation and degradation. | 2021 | Details |
| A46918 | 34282217 | Sci Rep | Elevated S-adenosylhomocysteine induces adipocyte dysfunction to promote alcohol-associated liver steatosis. | 2021 | Details |
| A46930 | 33860120 | Hepatol Commun | Clinical Presentation and Gene Expression of Acute Alcohol-Induced Microvesicular Steatosis Mimicking Alcoholic Hepatitis. | 2021 | Details |
| A46939 | 33481293 | FASEB J | Beneficial effects of an endogenous enrichment in n3-PUFAs on Wnt signaling are associated with attenuation of alcohol-mediated liver disease in mice. | 2021 | Details |
| A46941 | 33352397 | Cytokine | IL-8 exacerbates alcohol-induced fatty liver disease via the Akt/HIF-1α pathway in human IL-8-expressing mice. | 2020 | Details |
| A46957 | 32544093 | JCI Insight | Chronic-plus-binge alcohol intake induces production of proinflammatory mtDNA-enriched extracellular vesicles and steatohepatitis via ASK1/p38MAPKα-dependent mechanisms. | 2020 | Details |
| A46958 | 32418220 | Hepatology | Inhibition of Sphingosine-1-Phosphate-Induced Th17 Cells Ameliorates Alcohol-Associated Steatohepatitis in Mice. | 2021 | Details |
| A46960 | 32306456 | Liver Int | Dimethyl fumarate ameliorates hepatic inflammation in alcohol related liver disease. | 2020 | Details |
| A46962 | 32267550 | Alcohol Clin Exp Res | Dihydromyricetin Protects the Liver via Changes in Lipid Metabolism and Enhanced Ethanol Metabolism. | 2020 | Details |
| A46963 | 32206109 | Theranostics | NIK links inflammation to hepatic steatosis by suppressing PPARα in alcoholic liver disease. | 2020 | Details |
| A46966 | 32087348 | J Hepatol | Hepatic stellate cell activation promotes alcohol-induced steatohepatitis through Igfbp3 and SerpinA12. | 2020 | Details |
| A46967 | 32045450 | PLoS One | Mesenchymal stem cells reduce alcoholic hepatitis in mice via suppression of hepatic neutrophil and macrophage infiltration, and of oxidative stress. | 2020 | Details |
| A46969 | 31955762 | Food Res Int | Alteration of gut microbiota composition by short-term low-dose alcohol intake is restored by fermented rice liquor in mice. | 2019 | Details |
| A46976 | 31586017 | J Lipid Res | Decreased ω-6:ω-3 PUFA ratio attenuates ethanol-induced alterations in intestinal homeostasis, microbiota, and liver injury. | 2019 | Details |
| A46983 | 31321478 | J Mol Med (Berl) | S100A4 promotes inflammation but suppresses lipid accumulation via the STAT3 pathway in chronic ethanol-induced fatty liver. | 2019 | Details |
| A46984 | 31295533 | J Hepatol | The epigenetic regulator SIRT6 protects the liver from alcohol-induced tissue injury by reducing oxidative stress in mice. | 2019 | Details |
| A46986 | 31241423 | J Am Coll Nutr | Hepatoprotective Effect of Probiotic Lactobacillus rhamnosus GG Through the Modulation of Gut Permeability and Inflammasomes in a Model of Alcoholic Liver Disease in Zebrafish. | 2019 | Details |
| A46989 | 31168926 | Mol Nutr Food Res | Myricetin Ameliorates Ethanol-Induced Lipid Accumulation in Liver Cells by Reducing Fatty Acid Biosynthesis. | 2019 | Details |
| A46995 | 30935969 | Metabolism | Chitinase-3-like-1 deficiency attenuates ethanol-induced liver injury by inhibition of sterol regulatory element binding protein 1-dependent triglyceride synthesis. | 2019 | Details |
| A46997 | 30803859 | Dig Liver Dis | FXR deficiency alters bile acid pool composition and exacerbates chronic alcohol induced liver injury. | 2019 | Details |
| A47006 | 30256818 | PLoS One | Ethanol and unsaturated dietary fat induce unique patterns of hepatic ω-6 and ω-3 PUFA oxylipins in a mouse model of alcoholic liver disease. | 2018 | Details |
| A47009 | 30179264 | Hepatology | Pharmacological Inhibition of CCR2/5 Signaling Prevents and Reverses Alcohol-Induced Liver Damage, Steatosis, and Inflammation in Mice. | 2019 | Details |
| A47013 | 30071471 | Redox Biol | Pomegranate prevents binge alcohol-induced gut leakiness and hepatic inflammation by suppressing oxidative and nitrative stress. | 2018 | Details |
| A47015 | 29884546 | Mol Metab | Hepatocyte toll-like receptor 4 deficiency protects against alcohol-induced fatty liver disease. | 2018 | Details |
| A47016 | 29852391 | Biomed Pharmacother | Increased hepatic FAT/CD36, PTP1B and decreased HNF4A expression contributes to dyslipidemia associated with ethanol-induced liver dysfunction: Rescue effect of ginger extract. | 2018 | Details |
| A47020 | 29452206 | J Hepatol | SNX10 mediates alcohol-induced liver injury and steatosis by regulating the activation of chaperone-mediated autophagy. | 2018 | Details |
| A47023 | 29351393 | Am J Physiol Gastrointest Liver Physiol | Liver tissue metabolically transformed by alcohol induces immune recognition of liver self-proteins but not in vivo inflammation. | 2017 | Details |
| A47025 | 29337245 | Exp Mol Pathol | Hepatic alcohol dehydrogenase deficiency induces pancreatic injury in chronic ethanol feeding model of deer mice. | 2018 | Details |