Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A47676 | 33839215 | Food Chem Toxicol | Fasting-mediated metabolic and toxicity reprogramming impacts circulating microRNA levels in humans. | 2021 | Details |
| A47684 | 33738905 | Obes Rev | Neutral sphingomyelinase-2 and cardiometabolic diseases. | 2021 | Details |
| A47705 | 33297569 | Cells | Function of TREM1 and TREM2 in Liver-Related Diseases. | 2020 | Details |
| A47710 | 33163830 | Hepatol Commun | Donor Fecal Microbiota Transplantation Alters Gut Microbiota and Metabolites in Obese Individuals With Steatohepatitis. | 2020 | Details |
| A47711 | 33159158 | Cell Mol Immunol | Neutrophils in liver diseases: pathogenesis and therapeutic targets. | 2020 | Details |
| A47723 | 32932781 | Int J Mol Sci | mRNA Post-Transcriptional Regulation by AU-Rich Element-Binding Proteins in Liver Inflammation and Cancer. | 2020 | Details |
| A47726 | 32892258 | Hepatol Int | Interleukin-22 in alcoholic hepatitis and beyond. | 2020 | Details |
| A47728 | 32830851 | J Clin Endocrinol Metab | Identification of Proteins Associated with the Early Restoration of Insulin Sensitivity After Biliopancreatic Diversion. | 2020 | Details |
| A47734 | 32739404 | Antiviral Res | The chemokine receptor antagonist cenicriviroc inhibits the replication of SARS-CoV-2 in vitro. | 2020 | Details |
| A47737 | 32705602 | Adv Exp Med Biol | CGI-58: Versatile Regulator of Intracellular Lipid Droplet Homeostasis. | 2020 | Details |
| A47758 | 32366840 | Cell Death Dis | Oncogenic driver genes and tumor microenvironment determine the type of liver cancer. | 2020 | Details |
| A47771 | 32203160 | Oncogene | NCOA5 deficiency promotes a unique liver protumorigenic microenvironment through p21WAF1/CIP1 overexpression, which is reversed by metformin. | 2020 | Details |
| A47777 | 32108953 | Hepatology | Decreased Hepatocyte Autophagy Leads to Synergistic IL-1β and TNF Mouse Liver Injury and Inflammation. | 2020 | Details |
| A47785 | 31973190 | Nutrients | Current Knowledge about the Effect of Nutritional Status, Supplemented Nutrition Diet, and Gut Microbiota on Hepatic Ischemia-Reperfusion and Regeneration in Liver Surgery. | 2020 | Details |
| A47786 | 31936134 | Cells | Sterculic Acid: The Mechanisms of Action beyond Stearoyl-CoA Desaturase Inhibition and Therapeutic Opportunities in Human Diseases. | 2020 | Details |
| A47789 | 31895219 | Invest Radiol | Molecular Magnetic Resonance Imaging of Fibrin Deposition in the Liver as an Indicator of Tissue Injury and Inflammation. | 2020 | Details |
| A47792 | 31863814 | Pharmacol Ther | Therapeutic potential of targeting mixed lineage kinases in cancer and inflammation. | 2019 | Details |
| A47808 | 31492623 | Trends Parasitol | Immune Regulation of Metabolic Homeostasis by Helminths and Their Molecules. | 2019 | Details |
| A47820 | 31389060 | J Appl Toxicol | Free radicals, antioxidants, nuclear factor-E2-related factor-2 and liver damage. | 2019 | Details |
| A47823 | 31302759 | Handb Exp Pharmacol | Bile Acid-Activated Receptors: GPBAR1 (TGR5) and Other G Protein-Coupled Receptors. | 2019 | Details |
| A47835 | 31168508 | Hepatol Commun | Liver Macrophages: Old Dogmas and New Insights. | 2019 | Details |
| A47845 | 31027514 | J Med Case Rep | A suspected case of Clostridium perfringens sepsis with intravascular hemolysis after transhepatic arterial chemoembolization: a case report. | 2019 | Details |
| A47872 | 30515332 | Int J Hepatol | Video Capsule Endoscopy in the Assessment of Portal Hypertensive Enteropathy. | 2018 | Details |
| A47874 | 30357770 | Semin Liver Dis | Role of TGR5 (GPBAR1) in Liver Disease. | 2018 | Details |
| A47881 | 30141927 | J Med Chem | Design of Gut-Restricted Thiazolidine Agonists of G Protein-Coupled Bile Acid Receptor 1 (GPBAR1, TGR5). | 2018 | Details |
| A47886 | 30063802 | Hepatology | Emricasan (IDN-6556) Lowers Portal Pressure in Patients With Compensated Cirrhosis and Severe Portal Hypertension. | 2018 | Details |
| A47900 | 29733507 | Mol Nutr Food Res | High Fat Diets Composed of Palm Stearin and Olive Oil Equally Exacerbate Liver Inflammatory Damage and Metabolic Stress in Mice. | 2018 | Details |
| A47901 | 29687726 | Antioxid Redox Signal | The Association of Peroxiredoxin 4 with the Initiation and Progression of Hepatocellular Carcinoma. | 2018 | Details |
| A47914 | 29410095 | Biochem Biophys Res Commun | Loss of toll-like receptor 3 aggravates hepatic inflammation but ameliorates steatosis in mice. | 2018 | Details |
| A47916 | 29409022 | Endocrinology | Dysregulation of Kupffer Cells/Macrophages and Natural Killer T Cells in Steatohepatitis in LXRα Knockout Male Mice. | 2018 | Details |
| A47917 | 29404461 | Hepatol Commun | CAT-2003: A novel sterol regulatory element-binding protein inhibitor that reduces steatohepatitis, plasma lipids, and atherosclerosis in apolipoprotein E*3-Leiden mice. | 2017 | Details |
| A47923 | 29191940 | Am J Physiol Gastrointest Liver Physiol | Loss of cellular FLICE-inhibitory protein promotes acute cholestatic liver injury and inflammation from bile duct ligation. | 2017 | Details |
| A47946 | 28564720 | Semin Liver Dis | Inflammasomes in Liver Fibrosis. | 2017 | Details |
| A47949 | 28540526 | Eur J Nutr | High-fat diet inhibits PGC-1α suppressive effect on NFκB signaling in hepatocytes. | 2017 | Details |
| A47956 | 30271839 | Regen Ther | Phase I clinical study of liver regenerative therapy for cirrhosis by intrahepatic arterial infusion of freshly isolated autologous adipose tissue-derived stromal/stem (regenerative) cell. | 2017 | Details |
| A47957 | 28236037 | Inflammopharmacology | PPARα/γ antagonists reverse the ameliorative effects of osthole on hepatic lipid metabolism and inflammatory response in steatohepatitic rats. | 2017 | Details |
| A47959 | 28108987 | Hepatology | Activation of silent mating type information regulation 2 homolog 1 by human chorionic gonadotropin exerts a therapeutic effect on hepatic injury and inflammation. | 2017 | Details |
| A47960 | 28098353 | J Cell Physiol | The role of various peroxisome proliferator-activated receptors and their ligands in clinical practice. | 2017 | Details |
| A47974 | 27659424 | Am J Physiol Gastrointest Liver Physiol | Glycine prevents metabolic steatohepatitis in diabetic KK-Ay mice through modulation of hepatic innate immunity. | 2016 | Details |
| A47976 | 27618480 | Clin Res Hepatol Gastroenterol | Stress-induced cellular responses and cell death mechanisms during inflammatory cholangiopathies. | 2016 | Details |
| A47982 | 27425465 | J Steroid Biochem Mol Biol | Cardiopulmonary protective effects of the selective FXR agonist obeticholic acid in the rat model of monocrotaline-induced pulmonary hypertension. | 2016 | Details |
| A47990 | 27110066 | Mediators Inflamm | Anti-Inflammatory Effects of GLP-1-Based Therapies beyond Glucose Control. | 2016 | Details |
| A47993 | 27027234 | J Med Food | Extracts from Lentinula edodes (Shiitake) Edible Mushrooms Enriched with Vitamin D Exert an Anti-Inflammatory Hepatoprotective Effect. | 2016 | Details |
| A47999 | 26872435 | J Microbiol Immunol Infect | Serum pentraxin-3 and tumor necrosis factor-like weak inducer of apoptosis (TWEAK) predict severity of infections in acute decompensated cirrhotic patients. | 2016 | Details |
| A48001 | 26844528 | Hepatology | Oncogenic driver genes and the inflammatory microenvironment dictate liver tumor phenotype. | 2016 | Details |
| A48003 | 26811456 | Proc Natl Acad Sci U S A | Obeticholic acid, a synthetic bile acid agonist of the farnesoid X receptor, attenuates experimental autoimmune encephalomyelitis. | 2016 | Details |
| A48006 | 26781175 | Mol Med Rep | TLR4‑dependent signaling pathway modulation: A novel mechanism by which pioglitazone protects against nutritional fibrotic steatohepatitis in mice. | 2016 | Details |
| A48009 | 26686910 | Reprod Toxicol | Anti-inflammatory potential of β-cryptoxanthin against LPS-induced inflammation in mouse Sertoli cells. | 2015 | Details |
| A48010 | 26634212 | Biomed Res Int | The Influence of α-Lipoic Acid and Garlic Administration on Biomarkers of Oxidative Stress and Inflammation in Rabbits Exposed to Oxidized Nutrition Oils. | 2015 | Details |
| A48029 | 26075502 | J Dtsch Dermatol Ges | Early detection of comorbidity in psoriasis: recommendations of the National Conference on Healthcare in Psoriasis. | 2015 | Details |
| A48030 | 26020068 | Drugs Today (Barc) | A report from the European Association for the Study of the Liver's 50th International Liver Congress (April 22-26 - Vienna, Austria). | 2015 | Details |
| A48046 | 25763828 | Radiology | Combined Use of MR Fat Quantification and MR Elastography in Living Liver Donors: Can It Reduce the Need for Preoperative Liver Biopsy? | 2015 | Details |
| A48056 | 25473202 | World J Gastroenterol | Red cell distribution width and nonalcoholic steatohepatitis. | 2014 | Details |
| A48059 | 25392256 | Int J Colorectal Dis | The effect of body weight on the severity and clinical course of ulcerative colitis. | 2014 | Details |
| A48079 | 24726754 | Gastroenterology | Loss of CD28 expression by liver-infiltrating T cells contributes to pathogenesis of primary sclerosing cholangitis. | 2014 | Details |
| A48121 | 22556142 | Am J Physiol Gastrointest Liver Physiol | Steatohepatitis in laboratory opossums exhibiting a high lipemic response to dietary cholesterol and fat. | 2012 | Details |
| A48127 | 22333480 | J Pharmacol Sci | Multiple mechanisms for the action of chymase inhibitors. | 2012 | Details |
| A48172 | 20697377 | Lab Invest | Monocyte chemoattractant protein-1 deficiency does not affect steatosis or inflammation in livers of mice fed a methionine-choline-deficient diet. | 2010 | Details |
| A48176 | 20660066 | Endocrinology | Curcumin protects hepatic stellate cells against leptin-induced activation in vitro by accumulating intracellular lipids. | 2010 | Details |
| A48179 | 20637063 | Arthritis Res Ther | Rare incidence of methotrexate-specific lesions in liver biopsy of patients with arthritis and elevated liver enzymes. | 2010 | Details |
| A48188 | 20223120 | Zhonghua Yi Xue Za Zhi | [Mechanism of hepatocyte regeneration inhibition in rats with liver fibrosis induced by lipogenic methionine-choline- deficient diet]. | 2009 | Details |
| A48197 | 20008134 | Am J Pathol | Tissue factor-deficiency and protease activated receptor-1-deficiency reduce inflammation elicited by diet-induced steatohepatitis in mice. | 2009 | Details |
| A48203 | 19901911 | Lab Invest | Curcumin limits the fibrogenic evolution of experimental steatohepatitis. | 2009 | Details |
| A48205 | 19808779 | Endocrinology | Curcumin inhibits srebp-2 expression in activated hepatic stellate cells in vitro by reducing the activity of specificity protein-1. | 2009 | Details |
| A48209 | 19735301 | Fundam Clin Pharmacol | Effects of β-aminoisobutyric acid on leptin production and lipid homeostasis: mechanisms and possible relevance for the prevention of obesity. | 2009 | Details |
| A48219 | 19407661 | J Clin Gastroenterol | Visceral obesity and hypoadiponectinemia are significant determinants of hepatic dysfunction: An epidemiologic study of 3827 Japanese subjects. | 2010 | Details |
| A48243 | 18956299 | Semin Liver Dis | Multiple inflammatory and serum amyloid A positive telangiectatic hepatic adenomas with glycogenated nuclei arising in a background of nonalcoholic steatohepatitis. | 2008 | Details |
| A48245 | 18941030 | JPEN J Parenter Enteral Nutr | An evaluation of the model for end-stage liver disease and serum C-reactive protein as prognostic markers in intestinal failure patients on parenteral nutrition. | 2008 | Details |
| A48249 | 18715620 | Hum Pathol | Apoptosis markers in liver biopsy of nonalcoholic steatohepatitis in pediatric patients. | 2008 | Details |
| A48254 | 18408454 | Curr Opin Gastroenterol | Hepatobiliary pathology. | 2008 | Details |
| A48272 | 17916356 | Gastroenterology | Viral and host factors induce macrophage activation and loss of toll-like receptor tolerance in chronic HCV infection. | 2007 | Details |
| A48285 | 17369113 | Dig Liver Dis | Essential hypertension and chronic viral hepatitis. | 2007 | Details |
| A48302 | 17023554 | Am J Physiol Gastrointest Liver Physiol | Increased intestinal permeability in obese mice: new evidence in the pathogenesis of nonalcoholic steatohepatitis. | 2006 | Details |
| A48317 | 30290456 | Expert Rev Endocrinol Metab | Obesity, insulin resistance, Type 2 diabetes and free fatty acids. | 2006 | Details |
| A48321 | 16762632 | Gastroenterology | Metformin prevents alcohol-induced liver injury in the mouse: Critical role of plasminogen activator inhibitor-1. | 2006 | Details |
| A48331 | 16344599 | Alcohol Clin Exp Res | Modulation of non-alcoholic steatohepatitis by pattern recognition receptors in mice: the role of toll-like receptors 2 and 4. | 2005 | Details |
| A48349 | 15703634 | Curr Opin Gastroenterol | Nutritional supplements and alternative medicine. | 2004 | Details |
| A48357 | 15368448 | Hepatology | Norepinephrine regulates hepatic innate immune system in leptin-deficient mice with nonalcoholic steatohepatitis. | 2004 | Details |
| A48359 | 15329221 | Zhonghua Gan Zang Bing Za Zhi | [Expression of CD35 on erythrocyte and the changes of serum inflammatory cytokines in patients with nonalcoholic steatohepatitis and its immune regulation]. | 2004 | Details |
| A48396 | 12568185 | Obes Surg | Liver damage in obese patients. | 2002 | Details |
| A48404 | 12360490 | Gastroenterology | Murine leptin deficiency alters Kupffer cell production of cytokines that regulate the innate immune system. | 2002 | Details |
| A48408 | 12118106 | Mod Pathol | Kupffer cell aggregation and perivenular distribution in steatohepatitis. | 2002 | Details |
| A48428 | 11269008 | Hepatogastroenterology | Hepatic stellate cell activation occurs in nonalcoholic steatohepatitis. | 2001 | Details |
| A48434 | 11097478 | J Hepatol | Characterization of pathogenic and prognostic factors of nonalcoholic steatohepatitis associated with obesity. | 2000 | Details |
| A48468 | 8942745 | Gastroenterology | Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation. | 1996 | Details |
| A48495 | 7382552 | Mayo Clin Proc | Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease. | 1980 | Details |
| A48501 | 35258349 | Am J Physiol Gastrointest Liver Physiol | Bile Acid Detergency: Permeability, Inflammation and Effects of Sulfation. | 2022 | Details |
| A48509 | 35100953 | Curr Pharm Des | Immune response studies based on P2X7 receptors: A Mini-Review. | 2022 | Details |
| A48526 | 34774873 | Life Sci | GPR40 agonist inhibits NLRP3 inflammasome activation via modulation of nuclear factor-κB and sarco/endoplasmic reticulum Ca2+-ATPase. | 2021 | Details |
| A48539 | 34483915 | Front Pharmacol | Anti-Adipogenic Effect of Alchemilla monticola is Mediated Via PI3K/AKT Signaling Inhibition in Human Adipocytes. | 2021 | Details |
| A48547 | 34290349 | Commun Biol | Dynamin-related protein 1 deficiency accelerates lipopolysaccharide-induced acute liver injury and inflammation in mice. | 2021 | Details |
| A48553 | 34220440 | Front Neurosci | The Potential Role of Inflammation in Modulating Endogenous Hippocampal Neurogenesis After Spinal Cord Injury. | 2021 | Details |
| A48562 | 34068269 | Int J Mol Sci | Alcohol-Related Liver Disease: Basic Mechanisms and Clinical Perspectives. | 2021 | Details |
| A48573 | 33815359 | Front Immunol | Adipocyte Fatty Acid-Binding Protein, Cardiovascular Diseases and Mortality. | 2021 | Details |
| A48582 | 33659253 | Front Cell Dev Biol | Polarization of Macrophages in Insects: Opening Gates for Immuno-Metabolic Research. | 2021 | Details |
| A48583 | 33624852 | J Food Biochem | Red yeast rice prevents chronic alcohol-induced liver disease by attenuating oxidative stress and inflammatory response in mice. | 2021 | Details |
| A48591 | 33477615 | Antioxidants (Basel) | The Influence of a Conjugated Pneumococcal Vaccination on Plasma Antibody Levels against Oxidized Low-Density Lipoprotein in Metabolic Disease Patients: A Single-Arm Pilot Clinical Trial. | 2021 | Details |
| A48612 | 33113429 | Biomed Pharmacother | Plant-derived natural therapeutics targeting cannabinoid receptors in metabolic syndrome and its complications: A review. | 2020 | Details |
| A48616 | 32941717 | Dermatol Online J | Secukinumab-associated localized granuloma annulare (SAGA): a case report and review of the literature. | 2020 | Details |
| A48617 | 32918343 | Helicobacter | Review: Extragastric diseases and Helicobacter pylori. | 2020 | Details |