Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A49217 | 35819592 | Pharmacol Rep | Suppression of nitric oxide synthase aggravates non-alcoholic steatohepatitis and atherosclerosis in SHRSP5/Dmcr rat via acceleration of abnormal lipid metabolism. | 2022 | Details |
| A49234 | 35813333 | Ann Transl Med | Yinzhihuang oral liquid protects against non-alcoholic steatohepatitis via modulation of the gut-liver axis in mice. | 2022 | Details |
| A49245 | 35811658 | Dis Markers | Pharmacological Mechanism of Ganlu Powder in the Treatment of NASH Based on Network Pharmacology and Molecular Docking. | 2022 | Details |
| A49246 | 35811319 | BMC Gastroenterol | Nonalcoholic steatohepatitis medical patient journey from the perspective of hepatologists, gastroenterologists and patients: a cross-sectional survey. | 2022 | Details |
| A49249 | 35811033 | Biochim Biophys Acta Mol Basis Dis | Macrophage-specific MyD88 deletion and pharmacological inhibition prevents liver damage in non-alcoholic fatty liver disease via reducing inflammatory response. | 2022 | Details |
| A49250 | 35810800 | Clin Chim Acta | Alpha-1 antitrypsin: a novel biomarker and potential therapeutic approach for metabolic diseases. | 2022 | Details |
| A49252 | 35809408 | Comput Biol Med | In silico and in vitro analysis of PPAR - α / γ dual agonists: Comparative evaluation of potential phytochemicals with anti-obesity drug orlistat. | 2022 | Details |
| A49261 | 35807127 | J Clin Med | Effects of HIV Infection in Plasma Free Fatty Acid Profiles among People with Non-Alcoholic Fatty Liver Disease. | 2022 | Details |
| A49265 | 35806447 | Int J Mol Sci | New Insights of OLFM2 and OLFM4 in Gut-Liver Axis and Their Potential Involvement in Nonalcoholic Fatty Liver Disease. | 2022 | Details |
| A49270 | 35806156 | Int J Mol Sci | The Importance of CXCL1 in the Physiological State and in Noncancer Diseases of the Oral Cavity and Abdominal Organs. | 2022 | Details |
| A49276 | 35804007 | Sci Rep | IκBζ regulates the development of nonalcoholic fatty liver disease through the attenuation of hepatic steatosis in mice. | 2022 | Details |
| A49297 | 35796003 | Int J Mol Med | Role of Ca2+ channels in non-alcoholic fatty liver disease and their implications for therapeutic strategies (Review). | 2022 | Details |
| A49300 | 35795340 | Nanotheranostics | Emerging Role of Edible Exosomes-Like Nanoparticles (ELNs) as Hepatoprotective Agents. | 2022 | Details |
| A49308 | 35792869 | FASEB J | Intestinal aberrant sphingolipid metabolism shaped-gut microbiome and bile acids metabolome in the development of hepatic steatosis. | 2022 | Details |
| A49311 | 35791792 | Rev Esp Enferm Dig | Liver stiffness accuracy by MR elastography in histologically proven non-alcoholic fatty liver disease patients: a Spanish cohort. | 2022 | Details |
| A49321 | 35789393 | Toxicol Sci | Increased Renal Expression of Complement Components in Patients with Liver Diseases: Nonalcoholic Steatohepatitis, Alcohol-Associated, Viral Hepatitis, and Alcohol-Viral Combination. | 2022 | Details |
| A49328 | 35787436 | Food Chem Toxicol | The hypolipidemic, anti-inflammatory and antioxidant effect of Kavolì® aqueous extract, a mixture of Brassica oleracea leaves, in a rat model of NAFLD. | 2022 | Details |
| A49330 | 35786619 | Turk J Gastroenterol | Therapeutic Effect of Crocin on the NASH Model by Targeting the Fas Receptor Signaling Pathway. | 2022 | Details |
| A49338 | 35784533 | Front Endocrinol (Lausanne) | Fufang Zhenzhu Tiaozhi Capsule Prevents Intestinal Inflammation and Barrier Disruption in Mice With Non-Alcoholic Steatohepatitis. | 2022 | Details |
| A49341 | 35783474 | Hepatol Forum | Role of serum hyaluronic acid in predicting necroinflammatory activity of the nonalcoholic fatty liver disease. | 2022 | Details |
| A49345 | 35782916 | Front Nutr | Metabolic and Microbiome Alterations Following the Enrichment of a High-Fat Diet With High Oleic Acid Peanuts Versus the Traditional Peanuts Cultivar in Mice. | 2022 | Details |
| A49348 | 35782337 | Gastroenterol Res Pract | Research Progress on the Mechanism of Acupuncture Treatment for Nonalcoholic Fatty Liver Disease. | 2022 | Details |
| A49353 | 35780715 | Growth Horm IGF Res | Expression of IGF-1 receptor and GH receptor in hepatic tissue of patients with nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. | 2022 | Details |
| A49358 | 35779256 | J Clin Endocrinol Metab | The GH/IGF-1 axis is associated with intrahepatic lipid content and hepatocellular damage in overweight/obesity. | 2022 | Details |
| A49359 | 35779187 | Cell Stress Chaperones | Modulation of endoplasmic reticulum stress via sulforaphane-mediated AMPK upregulation against nonalcoholic fatty liver disease in rats. | 2022 | Details |
| A49409 | 35760093 | Life Sci | The role of protein kinases as key drivers of metabolic dysfunction-associated fatty liver disease progression: New insights and future directions. | 2022 | Details |
| A49416 | 35757439 | Food Nutr Res | Citrus maxima and tea regulate AMPK signaling pathway to retard the progress of nonalcoholic fatty liver disease. | 2022 | Details |
| A49425 | 35754743 | PPAR Res | Liver Protective Effect of Fenofibrate in NASH/NAFLD Animal Models. | 2022 | Details |
| A49426 | 35753609 | J Ethnopharmacol | Poria cocos polysaccharides rescue pyroptosis-driven gut vascular barrier disruption in order to alleviates non-alcoholic steatohepatitis. | 2022 | Details |
| A49429 | 35752255 | J Control Release | Prebiotic-like cyclodextrin assisted silybin on NAFLD through restoring liver and gut homeostasis. | 2022 | Details |
| A49433 | 35750137 | J Hepatol | Immune mechanisms linking metabolic injury to inflammation and fibrosis in fatty liver disease - novel insights into cellular communication circuits. | 2022 | Details |
| A49434 | 35749236 | J Nat Prod | Xyloketal B Reverses Nutritional Hepatic Steatosis, Steatohepatitis, and Liver Fibrosis through Activation of the PPARα/PGC1α Signaling Pathway. | 2022 | Details |
| A49443 | 35748073 | Yonsei Med J | Canagliflozin Ameliorates Nonalcoholic Fatty Liver Disease by Regulating Lipid Metabolism and Inhibiting Inflammation through Induction of Autophagy. | 2022 | Details |
| A49459 | 35744831 | Molecules | Expatiating the Pharmacological and Nanotechnological Aspects of the Alkaloidal Drug Berberine: Current and Future Trends. | 2022 | Details |
| A49460 | 35744822 | Molecules | Neuroendocrine-Immune Regulatory Network of Eucommia ulmoides Oliver. | 2022 | Details |
| A49461 | 35744805 | Molecules | Drugs Targeting the A3 Adenosine Receptor: Human Clinical Study Data. | 2022 | Details |
| A49462 | 35744776 | Molecules | Metabolomic Approach for Rapid Identification of Antioxidants in Clinacanthus nutans Leaves with Liver Protective Potential. | 2022 | Details |
| A49463 | 35744053 | Medicina (Kaunas) | Deuterium-Reinforced Polyunsaturated Fatty Acids Prevent Diet-Induced Nonalcoholic Steatohepatitis by Reducing Oxidative Stress. | 2022 | Details |
| A49473 | 35743140 | Int J Mol Sci | Combined Therapy with a CCR2/CCR5 Antagonist and FGF21 Analogue Synergizes in Ameliorating Steatohepatitis and Fibrosis. | 2022 | Details |
| A49487 | 35739990 | Antioxidants (Basel) | Vanadium(IV)-Chlorodipicolinate Protects against Hepatic Steatosis by Ameliorating Lipid Peroxidation, Endoplasmic Reticulum Stress, and Inflammation. | 2022 | Details |
| A49493 | 35738176 | Biomed Pharmacother | Sex hormone binding globulin as a potential drug candidate for liver-related metabolic disorders treatment. | 2022 | Details |
| A49497 | 35736447 | Metabolites | Interactions between Tryptophan Metabolism, the Gut Microbiome and the Immune System as Potential Drivers of Non-Alcoholic Fatty Liver Disease (NAFLD) and Metabolic Diseases. | 2022 | Details |
| A49498 | 35736186 | Mar Drugs | Marine Chitooligosaccharide Alters Intestinal Flora Structure and Regulates Hepatic Inflammatory Response to Influence Nonalcoholic Fatty Liver Disease. | 2022 | Details |
| A49502 | 35734974 | J Cell Mol Med | A randomized, placebo-controlled clinical trial of hydrogen/oxygen inhalation for non-alcoholic fatty liver disease. | 2022 | Details |
| A49503 | 35733920 | J Immunol Res | Exploring and Verifying the Mechanism and Targets of Shenqi Pill in the Treatment of Nonalcoholic Steatohepatitis via Network Pharmacology and Experiments. | 2022 | Details |
| A49509 | 35731428 | Dig Dis Sci | Crohn's Disease Is Associated with Liver Fibrosis in Patients with Nonalcoholic Fatty Liver Disease. | 2022 | Details |
| A49512 | 35730208 | Clin Mol Hepatol | Auranofin attenuates hepatic steatosis and fibrosis in non-alcoholic fatty liver disease via NRF2 and NF-κB signaling pathways. | 2022 | Details |
| A49523 | 35727151 | Radiology | Two-dimensional Shear-Wave Elastography and US Attenuation Imaging for Nonalcoholic Steatohepatitis Diagnosis: A Cross-sectional, Multicenter Study. | 2022 | Details |
| A49524 | 35726797 | Food Funct | Astragalus mongholicus polysaccharides ameliorate hepatic lipid accumulation and inflammation as well as modulate gut microbiota in NAFLD rats. | 2022 | Details |
| A49528 | 35725929 | Genes Immun | The presence of interferon affects the progression of non-alcoholic fatty liver disease. | 2022 | Details |
| A49530 | 35724509 | Biomed Pharmacother | Diet-gut microbiota-epigenetics in metabolic diseases: From mechanisms to therapeutics. | 2022 | Details |
| A49531 | 35723408 | Curr Issues Mol Biol | Validation of a Quantification Method for Curcumin Derivatives and Their Hepatoprotective Effects on Nonalcoholic Fatty Liver Disease. | 2022 | Details |
| A49532 | 35723304 | Curr Issues Mol Biol | Tremella fuciformis Crude Polysaccharides Attenuates Steatosis and Suppresses Inflammation in Diet-Induced NAFLD Mice. | 2022 | Details |
| A49541 | 35721143 | Front Pharmacol | Medicinal Formula Huazhi-Rougan Attenuates Non-Alcoholic Steatohepatitis Through Enhancing Fecal Bile Acid Excretion in Mice. | 2022 | Details |
| A49542 | 35721123 | Front Pharmacol | Identifying Candidate Flavonoids for Non-Alcoholic Fatty Liver Disease by Network-Based Strategy. | 2022 | Details |
| A49544 | 35720181 | Oxid Med Cell Longev | Chrysin Attenuates Fructose-Induced Nonalcoholic Fatty Liver in Rats via Antioxidant and Anti-Inflammatory Effects: The Role of Angiotensin-Converting Enzyme 2/Angiotensin (1-7)/Mas Receptor Axis. | 2022 | Details |
| A49551 | 35717907 | Biochem Biophys Res Commun | S100A9 promotes inflammatory response in diabetic nonalcoholic fatty liver disease. | 2022 | Details |
| A49552 | 35717780 | Biomed Pharmacother | Postbiotics as potential new therapeutic agents for metabolic disorders management. | 2022 | Details |
| A49553 | 35716542 | Phytomedicine | Phillygenin ameliorates nonalcoholic fatty liver disease via TFEB-mediated lysosome biogenesis and lipophagy. | 2022 | Details |
| A49556 | 35714879 | J Ethnopharmacol | Betulinic acid prevents liver fibrosis by binding Lck and suppressing Lck in HSC activation and proliferation. | 2022 | Details |
| A49558 | 35714570 | Biochem Biophys Res Commun | TSC22D4 promotes TGFβ1-induced activation of hepatic stellate cells. | 2022 | Details |
| A49592 | 35700593 | Nutrition | Short-term high-fat and high-carbohydrate diets increase susceptibility to liver injury by inducing hepatic procoagulant and proinflammatory conditions with different balances. | 2022 | Details |
| A49612 | 35692179 | Obes Rev | Evaluation of nonalcoholic fatty liver disease (NAFLD) in severe obesity using noninvasive tests and imaging techniques. | 2022 | Details |
| A49616 | 35690649 | Lab Invest | RNA adenosine deaminase (ADAR1) alleviates high-fat diet-induced nonalcoholic fatty liver disease by inhibiting NLRP3 inflammasome. | 2022 | Details |
| A49621 | 35689091 | Acta Pharmacol Sin | Dectin-1 plays a deleterious role in high fat diet-induced NAFLD of mice through enhancing macrophage activation. | 2022 | Details |
| A49627 | 35685888 | Front Nutr | Probiotic Therapy With VSL#3® in Patients With NAFLD: A Randomized Clinical Trial. | 2022 | Details |
| A49632 | 35684158 | Nutrients | 11β-HSD1 Inhibitor Alleviates Non-Alcoholic Fatty Liver Disease by Activating the AMPK/SIRT1 Signaling Pathway. | 2022 | Details |
| A49640 | 35682957 | Int J Mol Sci | Smad3 Phospho-Isoform Signaling in Nonalcoholic Steatohepatitis. | 2022 | Details |
| A49652 | 35678800 | Turk J Gastroenterol | Effects of Orlistat or Telmisartan on the Serum Free Fatty Acids in Non-alcoholic Fatty Liver Disease Patients: An Open-Labeled Randomized Controlled Study. | 2022 | Details |
| A49653 | 35678658 | Curr Issues Mol Biol | Beneficial Effect of Fenofibrate and Silymarin on Hepatic Steatosis and Gene Expression of Lipogenic and Cytochrome P450 Enzymes in Non-Obese Hereditary Hypertriglyceridemic Rats. | 2022 | Details |
| A49656 | 35677516 | J Clin Exp Hepatol | The Association Between Chronic Plaque Psoriasis and Nonalcoholic Fatty Liver Disease in Indian Patients: Results of a Pilot Study. | 2021 | Details |
| A49661 | 35677503 | J Clin Exp Hepatol | The Effects of Pathogen-Associated Molecular Patterns on Peripheral Blood Monocytes in Patients with Non-alcoholic Fatty Liver Disease. | 2021 | Details |
| A49666 | 35677024 | Front Oral Health | Does Oral Endotoxin Contribute to Systemic Inflammation? | 2022 | Details |
| A49680 | 35672623 | Dig Dis Sci | Histologic Severity of Nonalcoholic Fatty Liver Disease Associates with Reduced Bone Mineral Density in Children. | 2022 | Details |
| A49684 | 35671973 | Mol Metab | Sphingosine kinase 1 mediates sexual dimorphism in fibrosis in a mouse model of NASH. | 2022 | Details |
| A49685 | 35671811 | Life Sci | Vildagliptin alleviates liver fibrosis in NASH diabetic rats via modulation of insulin resistance, oxidative stress, and inflammatory cascades. | 2022 | Details |
| A49691 | 35668917 | J Inflamm Res | Melatonin Suppresses NLRP3 Inflammasome Activation via TLR4/NF-κB and P2X7R Signaling in High-Fat Diet-Induced Murine NASH Model. | 2022 | Details |
| A49710 | 35662732 | Front Pharmacol | Mendelian Randomization Rules Out Causation Between Inflammatory Bowel Disease and Non-Alcoholic Fatty Liver Disease. | 2022 | Details |
| A49733 | 35654975 | Nat Genet | A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation. | 2022 | Details |
| A49736 | 35654350 | J Ethnopharmacol | Danhe granule ameliorates nonalcoholic steatohepatitis and fibrosis in rats by inhibiting ceramide de novo synthesis related to CerS6 and CerK. | 2022 | Details |
| A49745 | 35651599 | Psoriasis (Auckl) | Comorbid Psoriasis and Metabolic Syndrome: Clinical Implications and Optimal Management. | 2022 | Details |
| A49749 | 35648974 | J Clin Gastroenterol | Steroid Use and Risk of Nonalcoholic Fatty Liver Disease in Patients With Inflammatory Bowel Disease: Systematic Review and Meta-analysis. | 2022 | Details |
| A49751 | 35647758 | J Clin Endocrinol Metab | Normal HDL cholesterol efflux and anti-inflammatory capacities in type 2 diabetes despite lipidomic abnormalities. | 2022 | Details |
| A49754 | 35646540 | Acta Pharm Sin B | Bile acid coordinates microbiota homeostasis and systemic immunometabolism in cardiometabolic diseases. | 2021 | Details |
| A49762 | 35644678 | J Cannabis Res | THC and CBD affect metabolic syndrome parameters including microbiome in mice fed high fat-cholesterol diet. | 2022 | Details |
| A49763 | 35644622 | BMC Gastroenterol | The association between dietary inflammation scores and non-alcoholic fatty liver diseases in Iranian adults. | 2022 | Details |
| A49770 | 35643287 | J Nutr Biochem | Opisthorchis viverrini infection induces metabolic disturbances in hamsters fed with high fat/high fructose diets: Implications for liver and kidney pathologies. | 2022 | Details |
| A49775 | 35642168 | Sichuan Da Xue Xue Bao Yi Xue Ban | [Research Progress in High-Sugar Diet and Inflammatory Diseases]. | 2022 | Details |
| A49787 | 35637160 | J Gastroenterol Hepatol | Epidemiological trends of gastrointestinal and liver diseases in Malaysia: A single-center observational study. | 2022 | Details |
| A49797 | 35635048 | Ann Med | Role of silymarin as antioxidant in clinical management of chronic liver diseases: a narrative review. | 2022 | Details |
| A49800 | 35634340 | Front Immunol | The Potential Role of Gut Microbial-Derived Exosomes in Metabolic-Associated Fatty Liver Disease: Implications for Treatment. | 2022 | Details |
| A49801 | 35634148 | Front Physiol | Metabolic Diffusion in Neuropathologies: The Relevance of Brain-Liver Axis. | 2022 | Details |
| A49802 | 35633911 | World J Gastroenterol | Peroxisome proliferator-activated receptor-alpha activation and dipeptidyl peptidase-4 inhibition target dysbiosis to treat fatty liver in obese mice. | 2022 | Details |
| A49809 | 35630624 | Molecules | Hepatoprotective Effects of Ixeris chinensis on Nonalcoholic Fatty Liver Disease Induced by High-Fat Diet in Mice: An Integrated Gut Microbiota and Metabolomic Analysis. | 2022 | Details |
| A49810 | 35630058 | Medicina (Kaunas) | Chronic Inflammation-A Link between Nonalcoholic Fatty Liver Disease (NAFLD) and Dysfunctional Adipose Tissue. | 2022 | Details |
| A49821 | 35628443 | Int J Mol Sci | Role of Sodium-Glucose Co-Transporter 2 Inhibitors in the Regulation of Inflammatory Processes in Animal Models. | 2022 | Details |
| A49823 | 35628290 | Int J Mol Sci | Oxy210, a Semi-Synthetic Oxysterol, Exerts Anti-Inflammatory Effects in Macrophages via Inhibition of Toll-like Receptor (TLR) 4 and TLR2 Signaling and Modulation of Macrophage Polarization. | 2022 | Details |
| A49836 | 35624839 | Antioxidants (Basel) | Modulation of Oxidative Stress-Induced Senescence during Non-Alcoholic Fatty Liver Disease. | 2022 | Details |
| A49837 | 35624786 | Antioxidants (Basel) | The Role and Mechanisms of Selenium Supplementation on Fatty Liver-Associated Disorder. | 2022 | Details |
| A49838 | 35624769 | Antioxidants (Basel) | Ramulus Mori (Sangzhi) Alkaloids Alleviate High-Fat Diet-Induced Obesity and Nonalcoholic Fatty Liver Disease in Mice. | 2022 | Details |