Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Glucagon575 records.
Article ID | PMID | Source | Title | Publish Year | |
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A49279 | 35803320 | Metabolism | Recent guidelines for non-alcoholic fatty liver disease (NAFLD): Are they already outdated and in need of supplementation? | 2022 | Details |
A49360 | 35778847 | Lipids | Structurally-engineered fatty acid 1024 (SEFA-1024) improves diet-induced obesity, insulin resistance, and fatty liver disease. | 2022 | Details |
A49548 | 35718339 | Mol Metab | Hepatocyte cholesterol content modulates glucagon receptor signalling. | 2022 | Details |
A49572 | 35709779 | Acta Gastroenterol Belg | Non-invasive screening, staging and management of metabolic dysfunction-associated fatty liver disease (MAFLD) in type 2 diabetes mellitus patients: what do we know so far ? | 2022 | Details |
A49574 | 35709586 | Diabetes Metab Syndr | Impact of semaglutide on biochemical and radiologic measures of metabolic-dysfunction associated fatty liver disease across the spectrum of glycaemia: A meta-analysis. | 2022 | Details |
A49608 | 35693370 | Cureus | Comparing the Efficacy and Safety of Obeticholic Acid and Semaglutide in Patients With Non-Alcoholic Fatty Liver Disease: A Systematic Review. | 2022 | Details |
A49709 | 35662921 | Front Nutr | High Protein Diets Improve Liver Fat and Insulin Sensitivity by Prandial but Not Fasting Glucagon Secretion in Type 2 Diabetes. | 2022 | Details |
A49718 | 35659603 | Clin Res Hepatol Gastroenterol | Effect of novel glucose lowering agents on non-alcoholic fatty liver disease: A systematic review and meta-analysis. | 2022 | Details |
A49721 | 35657697 | Diabetes | Regulation of Hepatic Lipid and Glucose Metabolism by INSP3R1. | 2022 | Details |
A49722 | 35657688 | Diabetes | The Liver-Alpha Cell Axis in Health and in Disease. | 2022 | Details |
A49748 | 35650449 | Pharm Res | Therapeutic Potential of Semaglutide, a Newer GLP-1 Receptor Agonist, in Abating Obesity, Non-Alcoholic Steatohepatitis and Neurodegenerative diseases: A Narrative Review. | 2022 | Details |
A49754 | 35646540 | Acta Pharm Sin B | Bile acid coordinates microbiota homeostasis and systemic immunometabolism in cardiometabolic diseases. | 2021 | Details |
A49802 | 35633911 | World J Gastroenterol | Peroxisome proliferator-activated receptor-alpha activation and dipeptidyl peptidase-4 inhibition target dysbiosis to treat fatty liver in obese mice. | 2022 | Details |
A49813 | 35629915 | Metabolites | Renin-Angiotensin System in Liver Metabolism: Gender Differences and Role of Incretins. | 2022 | Details |
A49829 | 35625757 | Biomedicines | Comparative Transcriptome Analysis Reveals That Exendin-4 Improves Steatosis in HepG2 Cells by Modulating Signaling Pathways Related to Lipid Metabolism. | 2022 | Details |
A49865 | 35614896 | Visc Med | Diagnostic and Therapy of Nonalcoholic Fatty Liver Disease: A Narrative Review. | 2021 | Details |
A49962 | 35581956 | Hepatol Commun | Favorable impact of long-term SGLT2 inhibitor for NAFLD complicated by diabetes mellitus: A 5-year follow-up study. | 2022 | Details |
A49988 | 35569886 | Endocr Pract | American Association of Clinical Endocrinology Clinical Practice Guideline for the Diagnosis and Management of Nonalcoholic Fatty Liver Disease in Primary Care and Endocrinology Clinical Settings: Co-Sponsored by the American Association for the Study of Liver Diseases (AASLD). | 2022 | Details |
A50123 | 35512974 | Fertil Steril | Nonalcoholic fatty liver disease and obstructive sleep apnea in women with polycystic ovary syndrome. | 2022 | Details |
A50133 | 35508252 | Arch Biochem Biophys | Eugenol alleviated nonalcoholic fatty liver disease in rat via a gut-brain-liver axis involving glucagon-like Peptide-1. | 2022 | Details |
A50136 | 35507280 | Curr Atheroscler Rep | Comprehensive Review and Updates on Holistic Approach Towards Non-Alcoholic Fatty Liver Disease Management with Cardiovascular Disease. | 2022 | Details |
A50153 | 35501557 | Curr Obes Rep | Anti-obesity Medications for the Management of Nonalcoholic Fatty Liver Disease. | 2022 | Details |
A50166 | 35494531 | Diabetes Metab Syndr Obes | Current Perspectives on Nonalcoholic Fatty Liver Disease in Women with Polycystic Ovary Syndrome. | 2022 | Details |
A50239 | 35462330 | Biomed Pharmacother | Update of Indoles: Promising molecules for ameliorating metabolic diseases. | 2022 | Details |
A50241 | 35461369 | Sci Rep | Effects of ALT-801, a GLP-1 and glucagon receptor dual agonist, in a translational mouse model of non-alcoholic steatohepatitis. | 2022 | Details |
A50298 | 35439567 | J Hepatol | Safety and efficacy of combination therapy with semaglutide, cilofexor and firsocostat in patients with non-alcoholic steatohepatitis: A randomised, open-label phase II trial. | 2022 | Details |
A50334 | 35430025 | J Clin Lipidol | JCL Roundtable. Obesity, Diabetes, and Liver Disease in Relation to Cardiovascular Risk. | 2022 | Details |
A50386 | 35409028 | Int J Mol Sci | SGLT2 Inhibitors as the Most Promising Influencers on the Outcome of Non-Alcoholic Fatty Liver Disease. | 2022 | Details |
A50648 | 35316465 | Curr Diab Rep | Implementation of Cardiometabolic Centers and Training Programs. | 2022 | Details |
A50654 | 35312970 | Diabetes Ther | Additional Effect of Luseogliflozin on Semaglutide in Nonalcoholic Steatohepatitis Complicated by Type 2 Diabetes Mellitus: An Open-Label, Randomized, Parallel-Group Study. | 2022 | Details |
A50724 | 35286799 | Clin Mol Hepatol | Old and new classes of glucose-lowering agents as treatments for non-alcoholic fatty liver disease: a narrative review. | 2022 | Details |
A50745 | 35280867 | Front Med (Lausanne) | Efficacy of Off-Label Therapy for Non-alcoholic Fatty Liver Disease in Improving Non-invasive and Invasive Biomarkers: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials. | 2022 | Details |
A50788 | 35266164 | Aliment Pharmacol Ther | Review article: role of glucagon-like peptide-1 receptor agonists in non-alcoholic steatohepatitis, obesity and diabetes-what hepatologists need to know. | 2022 | Details |
A50948 | 31402898 | Front Endocrinol (Lausanne) | Editorial: Gastrointestinal Hormones. | 2019 | Details |
A51161 | 35427802 | Clin Res Hepatol Gastroenterol | The mTORC1/AMPK pathway plays a role in the beneficial effects of semaglutide (GLP-1 receptor agonist) on the liver of obese mice. | 2022 | Details |
A51317 | 35674880 | Clin Pharmacokinet | Effects of Hepatic Impairment on the Pharmacokinetics of the Dual GIP and GLP-1 Receptor Agonist Tirzepatide. | 2022 | Details |
A51332 | 35535116 | J Clin Exp Hepatol | An Approach to the Management of Diabetes Mellitus in Cirrhosis: A Primer for the Hepatologist. | 2021 | Details |
A51388 | 30623143 | JACC Basic Transl Sci | The GLP-1 Analogs Liraglutide and Semaglutide Reduce Atherosclerosis in ApoE-/- and LDLr-/- Mice by a Mechanism That Includes Inflammatory Pathways. | 2018 | Details |
A51396 | 35830001 | Drugs | Tirzepatide: First Approval. | 2022 | Details |
A51412 | 35709720 | Semin Liver Dis | Non-Alcoholic Steatohepatitis Drug Development Pipeline: An Update. | 2022 | Details |
A51416 | 35680133 | Drug Metab Dispos | In vitro CYP450 enzyme down-regulation by GLP-1/glucagon co-agonist does not translate to observed drug-drug interactions in the clinic. | 2022 | Details |
A51536 | 35491295 | Trends Endocrinol Metab | SGLT-2 inhibitors and GLP-1 receptor agonists in metabolic dysfunction-associated fatty liver disease. | 2022 | Details |
A51617 | 35618993 | J Gastrointest Surg | Sleeve Gastrectomy Improves High-Fat Diet-Associated Hepatic Steatosis Independent of the Glucagon-like-Petpide-1 Receptor in Rats. | 2022 | Details |
A51686 | 34920733 | Cardiovasc Diabetol | Pharmacometabolomic profiles in type 2 diabetic subjects treated with liraglutide or glimepiride. | 2021 | Details |
A51719 | 34629258 | Nutr Metab Cardiovasc Dis | Changes in markers of hepatic steatosis and fibrosis in patients with type 2 diabetes during treatment with glucagon-like peptide-1 receptor agonists. A multicenter retrospective longitudinal study. | 2021 | Details |
A51772 | 34233623 | Cell Mol Biol Lett | Targeting the GPR119/incretin axis: a promising new therapy for metabolic-associated fatty liver disease. | 2021 | Details |
A51777 | 34143451 | FASEB J | Holdemanella biformis improves glucose tolerance and regulates GLP-1 signaling in obese mice. | 2021 | Details |
A51789 | 34064308 | Nutrients | Leptin Receptors Are Not Required for Roux-en-Y Gastric Bypass Surgery to Normalize Energy and Glucose Homeostasis in Rats. | 2021 | Details |
A51795 | 34039937 | J Clin Gastroenterol | Efficacy and Safety of Glucagon-like Peptide-1 Receptor Agonists in the Treatment of Metabolic Associated Fatty Liver Disease: A Systematic Review and Meta-analysis. | 2021 | Details |
A51872 | 33538983 | Obes Surg | Decrease of dipeptidyl peptidase 4 activity is associated with weight loss after bariatric surgery. | 2021 | Details |
A51886 | 33455774 | J Dairy Sci | Relationships between metabolic profiles and gene expression in liver and leukocytes of dairy cows in early lactation. | 2021 | Details |
A51991 | 32548470 | ACS Omega | Effects of Inulin Propionate Ester on Obesity-Related Metabolic Syndrome and Intestinal Microbial Homeostasis in Diet-Induced Obese Mice. | 2020 | Details |
A52096 | 31307210 | FASEB J | Ileal interposition surgery targets the hepatic TGF-β pathway, influencing gluconeogenesis and mitochondrial bioenergetics in the UCD-T2DM rat model of diabetes. | 2019 | Details |
A52109 | 31103416 | Biochem Pharmacol | Effects of Liraglutide and Fenretinide treatments on the diabetic phenotype of neuronal human BACE1 knock-in mice. | 2019 | Details |
A52153 | 30619718 | J Clin Transl Endocrinol | Metabolic effects of glucagon in humans. | 2018 | Details |
A52196 | 30212233 | Chronobiol Int | Timing of food intake is more potent than habitual voluntary exercise to prevent diet-induced obesity in mice. | 2018 | Details |
A52279 | 29371333 | Eur J Endocrinol | MECHANISMS IN ENDOCRINOLOGY: SGLT2 inhibitors: clinical benefits by restoration of normal diurnal metabolism? | 2018 | Details |
A52289 | 29074588 | Arterioscler Thromb Vasc Biol | GLP-1 Elicits an Intrinsic Gut-Liver Metabolic Signal to Ameliorate Diet-Induced VLDL Overproduction and Insulin Resistance. | 2017 | Details |
A52370 | 28086952 | J Med Case Rep | Glucagon-like peptide-1 analogues - an efficient therapeutic option for the severe insulin resistance of lipodystrophic syndromes: two case reports. | 2017 | Details |
A52475 | 26579439 | Acta Pharm Sin B | Bile acid nuclear receptor FXR and digestive system diseases. | 2015 | Details |
A52477 | 26546347 | J Cardiovasc Magn Reson | Time course of cardiometabolic alterations in a high fat high sucrose diet mice model and improvement after GLP-1 analog treatment using multimodal cardiovascular magnetic resonance. | 2015 | Details |
A52501 | 26287659 | Int J Dev Neurosci | Short term exendin-4 treatment reduces markers of metabolic disorders in female offspring of obese rat dams. | 2015 | Details |
A52528 | 25972231 | Diabetologia | Oncostatin M is a potential agent for the treatment of obesity and related metabolic disorders: a study in mice. | 2015 | Details |
A52668 | 23886976 | Benef Microbes | Gut microbiota controls adipose tissue expansion, gut barrier and glucose metabolism: novel insights into molecular targets and interventions using prebiotics. | 2014 | Details |
A52710 | 23118444 | J Lipid Res | AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism. | 2012 | Details |
A52804 | 21549160 | Regul Pept | GLP-1-derived nonapeptide GLP-1(28-36)amide inhibits weight gain and attenuates diabetes and hepatic steatosis in diet-induced obese mice. | 2011 | Details |
A52832 | 21151924 | PLoS One | Reversal of obesity and insulin resistance by a non-peptidic glucagon-like peptide-1 receptor agonist in diet-induced obese mice. | 2010 | Details |
A53080 | 15520626 | MedGenMed | Etiology and pathogenesis of necrolytic migratory erythema: review of the literature. | 2004 | Details |
A53096 | 15010338 | Am J Physiol Endocrinol Metab | Elevated circulating adiponectin levels in liver cirrhosis are associated with reduced liver function and altered hepatic hemodynamics. | 2004 | Details |
A53097 | 14747292 | Diabetes | Reduction in glucagon receptor expression by an antisense oligonucleotide ameliorates diabetic syndrome in db/db mice. | 2004 | Details |
A53105 | 14507025 | J Dairy Sci | Effects of exogenous glucagon on lipids in lipoproteins and liver of lactating dairy cows. | 2003 | Details |
A53155 | 9670624 | Indian J Pathol Microbiol | Observations on hepatic structure and function in fibro-calculous pancreatic diabetes (FCPD) vis-a-vis other diabetic subtypes. | 1998 | Details |
A53179 | 2661933 | Mech Ageing Dev | Effect of chronic caloric restriction on hepatic enzymes of intermediary metabolism in the male Fischer 344 rat. | 1989 | Details |
A53189 | 201171 | Am J Med | Corticosteroid-responsive skeletal muscle disease associated with partial carnitine deficiency: studies of liver and metabolic alterations. | 1977 | Details |
A53192 | 1175860 | Diabetes | Metabolic studies in the pyelonephritic rat. | 1975 | Details |