Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Glutathione718 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A31722 | 29983886 | Oncotarget | Oral administration of fructose exacerbates liver fibrosis and hepatocarcinogenesis via increased intestinal permeability in a rat steatohepatitis model. | 2018 | Details |
| A32331 | 28704693 | Ecotoxicol Environ Saf | Investigation of arsenic accumulation and biochemical response of in vitro developed Vetiveria zizanoides plants. | 2017 | Details |
| A32341 | 28680450 | Evid Based Complement Alternat Med | An ErChen and YinChen Decoction Ameliorates High-Fat-Induced Nonalcoholic Steatohepatitis in Rats by Regulating JNK1 Signaling Pathway. | 2017 | Details |
| A32820 | 27357826 | Mol Cell Biochem | MCD diet-induced steatohepatitis is associated with alterations in asymmetric dimethylarginine (ADMA) and its transporters. | 2016 | Details |
| A32945 | 27021876 | Toxicol In Vitro | Chebulic acid prevents hepatic fibrosis induced by advanced glycation end-products in LX-2 cell by modulating Nrf2 translocation via ERK pathway. | 2016 | Details |
| A32978 | 26937962 | PLoS One | Genetic Association and Gene-Gene Interaction Reveal Genetic Variations in ADH1B, GSTM1 and MnSOD Independently Confer Risk to Alcoholic Liver Diseases in India. | 2016 | Details |
| A33013 | 26863200 | Inorg Chem | Hydrosulfide Adducts of Organo-Iridium Anticancer Complexes. | 2016 | Details |
| A33018 | 26856696 | J Neuroinflammation | Sodium thiosulfate attenuates glial-mediated neuroinflammation in degenerative neurological diseases. | 2016 | Details |
| A33696 | 25385666 | Ir J Med Sci | Liver injury attenuation by curcumin in a rat NASH model: an Nrf2 activation-mediated effect? | 2014 | Details |
| A33779 | 25169677 | Neurobiol Aging | Activated human microglia stimulate neuroblastoma cells to upregulate production of beta amyloid protein and tau: implications for Alzheimer's disease pathogenesis. | 2014 | Details |
| A33804 | 25122768 | J Biol Chem | Thiosulfate transfer mediated by DsrE/TusA homologs from acidothermophilic sulfur-oxidizing archaeon Metallosphaera cuprina. | 2014 | Details |
| A34016 | 24619556 | Hepatology | E2F1 is a novel fibrogenic gene that regulates cholestatic liver fibrosis through the Egr-1/SHP/EID1 network. | 2014 | Details |
| A34018 | 24614199 | Lab Invest | Curcumin eliminates the effect of advanced glycation end-products (AGEs) on the divergent regulation of gene expression of receptors of AGEs by interrupting leptin signaling. | 2014 | Details |
| A34125 | 26858882 | Cell Med | Electron Therapy Attenuated Elevated Alanine Aminotransferase and Oxidative Stress Values in Type 2 Diabetes-Induced Nonalcoholic Steatohepatitis of Rats. | 2013 | Details |
| A34160 | 24273738 | Redox Biol | Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and JNK MAPK. | 2013 | Details |
| A34169 | 24242936 | Hepatology | Noninvasive in vivo magnetic resonance measures of glutathione synthesis in human and rat liver as an oxidative stress biomarker. | 2014 | Details |
| A34216 | 24067460 | Int J Immunopathol Pharmacol | Sulphurous thermal water increases the release of the anti-inflammatory cytokine IL-10 and modulates antioxidant enzyme activity. | 2014 | Details |
| A34301 | 23822105 | Antioxid Redox Signal | Does hepatic oxidative stress enhance activation of nuclear factor-E2-related factor in patients with nonalcoholic steatohepatitis? | 2013 | Details |
| A34355 | 23665184 | J Hepatol | Pleiotropic effects of methionine adenosyltransferases deregulation as determinants of liver cancer progression and prognosis. | 2013 | Details |
| A34441 | 23448275 | Hepatol Res | Direct renin inhibitor, aliskiren, attenuates the progression of non-alcoholic steatohepatitis in the rat model. | 2013 | Details |
| A34685 | 22882855 | Chin Med J (Engl) | Pioglitazone ameliorates nonalcoholic steatohepatitis by down-regulating hepatic nuclear factor-kappa B and cyclooxygenases-2 expression in rats. | 2012 | Details |
| A34871 | 22363250 | Mar Drugs | Inhibitory effects of Ecklonia cava extract on high glucose-induced hepatic stellate cell activation. | 2011 | Details |
| A35001 | 22013536 | Int J Hepatol | NCX 1000 Alone or in Combination with Vitamin E Reverses Experimental Nonalcoholic Steatohepatitis in the Rat Similarly to UDCA. | 2011 | Details |
| A35002 | 22008477 | Life Sci | Cysteine aggravates palmitate-induced cell death in hepatocytes. | 2011 | Details |
| A35202 | 21452373 | Phytother Res | Black tea prevents high fat diet-induced non-alcoholic steatohepatitis. | 2011 | Details |
| A35224 | 21376711 | Chem Biol Interact | Cytotoxic molecular mechanisms and cytoprotection by enzymic metabolism or autoxidation for glyceraldehyde, hydroxypyruvate and glycolaldehyde. | 2011 | Details |
| A35259 | 21276150 | Hepatol Res | Pitavastatin inhibits hepatic steatosis and fibrosis in non-alcoholic steatohepatitis model rats. | 2011 | Details |
| A35338 | 21056947 | Hum Exp Toxicol | Teucrium polium reversed the MCD diet-induced liver injury in rats. | 2010 | Details |
| A35349 | 21042657 | Cryo Letters | Cryopreservation of protocorm-like bodies of the hybrid orchid Bratonia (Miltonia flavescens × Brassia longissima). | 2010 | Details |
| A35496 | 20539006 | Am J Physiol Gastrointest Liver Physiol | Diabetic KK-A(y) mice are highly susceptible to oxidative hepatocellular damage induced by acetaminophen. | 2010 | Details |
| A35544 | 20395294 | J Biol Chem | Specific contribution of methionine and choline in nutritional nonalcoholic steatohepatitis: impact on mitochondrial S-adenosyl-L-methionine and glutathione. | 2010 | Details |
| A35709 | 19856260 | Exp Clin Endocrinol Diabetes | Chronic acetonemia alters liver oxidative balance and lipid content in rats. A model of NASH? | 2009 | Details |
| A35720 | 19841616 | Lab Invest | Curcumin attenuates the effects of insulin on stimulating hepatic stellate cell activation by interrupting insulin signaling and attenuating oxidative stress. | 2009 | Details |
| A35732 | 19818291 | Eur J Intern Med | Oxidative stress and thyroid hormones in patients with liver diseases. | 2009 | Details |
| A35812 | 19638084 | J Gastroenterol Hepatol | Open-labeled pilot study of cysteine-rich whey protein isolate supplementation for nonalcoholic steatohepatitis patients. | 2009 | Details |
| A35838 | 19571235 | Am J Physiol Gastrointest Liver Physiol | Glycine and urea kinetics in nonalcoholic steatohepatitis in human: effect of intralipid infusion. | 2009 | Details |
| A35856 | 19552763 | J Pineal Res | Melatonin ameliorates methionine- and choline-deficient diet-induced nonalcoholic steatohepatitis in rats. | 2009 | Details |
| A35858 | 19551842 | Int J Cancer | Dietary lycopene and tomato extract supplementations inhibit nonalcoholic steatohepatitis-promoted hepatocarcinogenesis in rats. | 2010 | Details |
| A35896 | 19473437 | Hepatol Res | Adiponectin prevents progression of steatohepatitis in mice by regulating oxidative stress and Kupffer cell phenotype polarization. | 2009 | Details |
| A35943 | 19374265 | Indian J Biochem Biophys | Antioxidant potential of the root of Vetiveria zizanioides (L.) Nash. | 2009 | Details |
| A35969 | 19299451 | Endocrinology | Curcumin eliminates leptin's effects on hepatic stellate cell activation via interrupting leptin signaling. | 2009 | Details |
| A36101 | 19004024 | Int J Cancer | Nonalcoholic steatohepatitis induced by a high-fat diet promotes diethylnitrosamine-initiated early hepatocarcinogenesis in rats. | 2009 | Details |
| A36179 | 18806095 | J Nutr | N-acetylcysteine attenuates progression of liver pathology in a rat model of nonalcoholic steatohepatitis. | 2008 | Details |
| A36228 | 18689562 | J Am Coll Nutr | Prevention and reversion of nonalcoholic steatohepatitis in OB/OB mice by S-nitroso-N-acetylcysteine treatment. | 2008 | Details |
| A36348 | 18392239 | J Gastrointestin Liver Dis | Angiotensin II type 1 receptor antagonist improves the prognosis in rats displaying liver cirrhosis induced by a choline-deficient diet. | 2008 | Details |
| A36376 | 18349116 | Am J Physiol Endocrinol Metab | Partial leptin deficiency favors diet-induced obesity and related metabolic disorders in mice. | 2008 | Details |
| A36466 | 18082265 | Ecotoxicol Environ Saf | Potential of vetiver (Vetiveria zizanoides L. Nash) for phytoremediation of phenol. | 2007 | Details |
| A36550 | 17876880 | World J Gastroenterol | N-acetylcysteine attenuates oxidative stress and liver pathology in rats with non-alcoholic steatohepatitis. | 2007 | Details |
| A36577 | 17710550 | Dig Dis Sci | Methionine deficiency and hepatic injury in a dietary steatohepatitis model. | 2007 | Details |
| A36674 | 17477913 | Clin Biochem | Oxidative stress and antioxidant defenses in serum of patients with non-alcoholic steatohepatitis. | 2007 | Details |
| A36753 | 17331168 | Alcohol Clin Exp Res | Mitochondrial abnormality and oxidative stress in nonalcoholic steatohepatitis. | 2007 | Details |
| A36765 | 17311618 | Liver Int | Yo jyo hen shi ko, a novel Chinese herbal, prevents nonalcoholic steatohepatitis in ob/ob mice fed a high fat or methionine-choline-deficient diet. | 2007 | Details |
| A36768 | 17300698 | Hepatol Res | Longitudinal analysis of murine steatohepatitis model induced by chronic exposure to high-fat diet. | 2007 | Details |
| A36882 | 17023119 | Med Hypotheses | The role of triiodothyronine-induced substrate cycles in the hepatic response to overnutrition: thyroid hormone as an antioxidant. | 2006 | Details |
| A36886 | 17006938 | Hepatology | Leptin-mediated neovascularization is a prerequisite for progression of nonalcoholic steatohepatitis in rats. | 2006 | Details |
| A37091 | 16498637 | J Biochem Mol Toxicol | Glutathione-enhancing agents protect against steatohepatitis in a dietary model. | 2006 | Details |
| A37290 | 16042344 | Z Naturforsch C J Biosci | The possible role of hydroxylation in the detoxification of atrazine in mature vetiver (Chrysopogon zizanioides Nash) grown in hydroponics. | 2005 | Details |
| A37314 | 15980672 | Korean J Hepatol | [Antioxidant status in nonalcoholic steatohepatitis]. | 2005 | Details |
| A37379 | 15820484 | Clin Chim Acta | Glutathione metabolism and antioxidant enzymes in patients affected by nonalcoholic steatohepatitis. | 2005 | Details |
| A37621 | 15255956 | J Neurochem | The novel neuromodulator hydrogen sulfide: an endogenous peroxynitrite 'scavenger'? | 2004 | Details |
| A37724 | 15038668 | Ann Clin Lab Sci | Oxidative stress and enzymatic antioxidant status in patients with nonalcoholic steatohepatitis. | 2004 | Details |
| A37771 | 14694585 | Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi | [Lipoxygenase-mediated N-demethylation of pesticides in vitro]. | 2002 | Details |
| A38842 | 9802330 | Biochem Pharmacol | Concordance between enzyme activity and genotype of glutathione S-transferase theta (GSTT1). | 1998 | Details |
| A39242 | 8670055 | Biochem J | Isolation of a mouse theta glutathione S-transferase active with methylene chloride. | 1996 | Details |
| A39582 | 7979958 | Arch Toxicol | Metabolism of dichloromethane (methylene chloride) to formaldehyde in human erythrocytes: influence of polymorphism of glutathione transferase theta (GST T1-1). | 1994 | Details |
| A39990 | 2124383 | Toxicol Lett | NADPH-dependent reaction of paraquat in mouse brain microsomes. | 1990 | Details |
| A40087 | 1969182 | Toxicol Appl Pharmacol | Perchloroethylene-induced rat kidney tumors: an investigation of the mechanisms involved and their relevance to humans. | 1990 | Details |
| A40099 | 2306278 | Biochem Pharmacol | Oxidation of glycerol to formaldehyde by rat liver microsomes. Effects of cytochrome P-450 inducing agents. | 1990 | Details |
| A40324 | 3382392 | Biochem Biophys Res Commun | Oxidation of glycerol to formaldehyde by rat liver microsomes. | 1988 | Details |
| A40552 | 2937720 | Immunology | Inhibition of cell-mediated cytotoxicity by 2-cyclohexene-1-one: evidence for a role for glutathione and/or glutathione-protein interactions in cytolysis. | 1986 | Details |
| A40742 | 6729821 | Toxicol Appl Pharmacol | The toxicity and biotransformation of single doses of acetaminophen in dogs and cats. | 1984 | Details |
| A40765 | 6710510 | Toxicol Appl Pharmacol | The metabolism and disposition of hexachloro-1:3-butadiene in the rat and its relevance to nephrotoxicity. | 1984 | Details |
| A40781 | 6694103 | J Pharmacol Exp Ther | Role of microsomal and cytosolic glutathione S-transferases in the conjugation of hexachloro-1:3-butadiene and its possible relevance to toxicity. | 1984 | Details |
| A42297 | 34935193 | Fundam Clin Pharmacol | Hepatoprotective and therapeutic effects of resveratrol: A focus on anti-inflammatory and antioxidative activities. | 2022 | Details |
| A42359 | 34767670 | Biofactors | Vitamin D3 enhances the effects of omega-3 oils against metabolic dysfunction-associated fatty liver disease in rat. | 2021 | Details |
| A42663 | 33856704 | J Periodontol | Food restriction reduces hepatic alterations associated with experimental periodontitis. | 2021 | Details |
| A42680 | 33809508 | Pharmaceuticals (Basel) | Doxepin Exacerbates Renal Damage, Glucose Intolerance, Nonalcoholic Fatty Liver Disease, and Urinary Chromium Loss in Obese Mice. | 2021 | Details |
| A43035 | 32751062 | Int J Mol Sci | Consumption of Wild Rice (Zizania latifolia) Prevents Metabolic Associated Fatty Liver Disease through the Modulation of the Gut Microbiota in Mice Model. | 2020 | Details |
| A43509 | 31556117 | J Cell Physiol | Inhibition of tumor propellant glutathione peroxidase 4 induces ferroptosis in cancer cells and enhances anticancer effect of cisplatin. | 2019 | Details |
| A44001 | 30174510 | Saudi J Biol Sci | Effects of a medicinal plant Macrotyloma uniflorum (Lam.) Verdc.formulation (MUF) on obesity-associated oxidative stress-induced liver injury. | 2018 | Details |
| A44012 | 30153066 | Am J Physiol Endocrinol Metab | Glutathione S-transferase P deficiency induces glucose intolerance via JNK-dependent enhancement of hepatic gluconeogenesis. | 2018 | Details |
| A44614 | 27958883 | Antioxid Redox Signal | Glutaredoxin-1 Deficiency Causes Fatty Liver and Dyslipidemia by Inhibiting Sirtuin-1. | 2017 | Details |
| A44710 | 27635189 | Oxid Med Cell Longev | Liver Cholesterol Overload Aggravates Obstructive Cholestasis by Inducing Oxidative Stress and Premature Death in Mice. | 2016 | Details |
| A44729 | 27512925 | Liver Int | Gamma-glutamyltransferase-friend or foe within? | 2016 | Details |
| A44730 | 27511913 | Toxicol Appl Pharmacol | Hepatocyte-protective effect of nectandrin B, a nutmeg lignan, against oxidative stress: Role of Nrf2 activation through ERK phosphorylation and AMPK-dependent inhibition of GSK-3β. | 2016 | Details |
| A44755 | 27423982 | Eur J Intern Med | Homocysteine in nonalcoholic steatohepatitis: A reply. | 2016 | Details |
| A44773 | 27353275 | Eur J Intern Med | High levels of serum homocysteine in non-alcoholic steatohepatitis. | 2016 | Details |
| A44879 | 26997005 | Indian J Med Res | Gamma glutamyl transferase: A novel cardiovascular outfit for an old liver test. | 2016 | Details |
| A45205 | 25676807 | Eur J Intern Med | Circulating homocysteine in nonalcoholic fatty liver disease. | 2015 | Details |
| A45288 | 25372290 | PLoS One | Impact of the superoxide dismutase 2 Val16Ala polymorphism on the relationship between valproic acid exposure and elevation of γ-glutamyltransferase in patients with epilepsy: a population pharmacokinetic-pharmacodynamic analysis. | 2014 | Details |
| A45550 | 23970447 | Hum Exp Toxicol | Chunggan extract (CGX), methionine-and choline-deficient (MCD) diet-induced hepatosteatosis and oxidative stress in C57BL/6 mice. | 2013 | Details |
| A45557 | 23914059 | J Toxicol Pathol | Thioacetamide-induced Hepatocellular Necrosis Is Attenuated in Diet-induced Obese Mice. | 2013 | Details |
| A45634 | 23512597 | Obesity (Silver Spring) | Modest fructose beverage intake causes liver injury and fat accumulation in marginal copper deficient rats. | 2013 | Details |
| A45681 | 23298629 | J Hepatol | Drug-induced liver injury in obesity. | 2013 | Details |
| A45684 | 23295629 | Food Chem Toxicol | Protective effects of matrine against progression of high-fructose diet-induced steatohepatitis by enhancing antioxidant and anti-inflammatory defences involving Nrf2 translocation. | 2013 | Details |
| A45806 | 22647274 | J Pharmacol Exp Ther | Differences in early acetaminophen hepatotoxicity between obese ob/ob and db/db mice. | 2012 | Details |
| A45946 | 21908766 | Toxicol Sci | 3,5,5-trimethyl-hexanoyl-ferrocene diet protects mice from moderate transient acetaminophen-induced hepatotoxicity. | 2011 | Details |
| A46111 | 21038411 | Hepatology | Coffee reduces liver damage in a rat model of steatohepatitis: the underlying mechanisms and the role of polyphenols and melanoidins. | 2010 | Details |
| A46167 | 20633523 | J Acupunct Meridian Stud | Effects of Teucrium polium on Insulin Resistance in Nonalcoholic Steatohepatitis. | 2010 | Details |
| A46200 | 20402505 | J Proteome Res | Metabolomic assessment of the effect of dietary cholesterol in the progressive development of fatty liver disease. | 2010 | Details |