Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin resistance7794 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A03453 | 33994854 | Int J Biol Sci | Berberine alleviates lipid metabolism disorders via inhibition of mitochondrial complex I in gut and liver. | 2021 | Details |
| A03455 | 33994437 | Intern Med | Effects of Canagliflozin on Hepatic Steatosis, Visceral Fat and Skeletal Muscle among Patients with Type 2 Diabetes and Non-alcoholic Fatty Liver Disease. | 2021 | Details |
| A03456 | 33994069 | Cytokine | Changes in liver steatosis in HIV-positive women are associated with the BMI, but not with biomarkers. | 2021 | Details |
| A03464 | 33992322 | Food Res Int | Long-term supplementation with phenolic compounds from jaboticaba (Plinia jaboticaba (Vell.) Berg) reduces adiposophaty and improves glucose, lipid, and energy metabolism. | 2021 | Details |
| A03468 | 33991615 | Cell Signal | Secretory Galectin-3 promotes hepatic steatosis via regulation of the PPARγ/CD36 signaling pathway. | 2021 | Details |
| A03471 | 33991450 | Physiol Rep | Antisense oligonucleotide-mediated knockdown of Mpzl3 attenuates the negative metabolic effects of diet-induced obesity in mice. | 2021 | Details |
| A03474 | 33990765 | Acta Pharmacol Sin | Blueberry-derived exosomes-like nanoparticles ameliorate nonalcoholic fatty liver disease by attenuating mitochondrial oxidative stress. | 2021 | Details |
| A03478 | 33989548 | Cell | Mechanisms and disease consequences of nonalcoholic fatty liver disease. | 2021 | Details |
| A03482 | 33987427 | Ann Transl Med | Non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH)-related liver fibrosis: mechanisms, treatment and prevention. | 2021 | Details |
| A03492 | 33984335 | Metabolism | Fenofibrate, a PPARα agonist, reduces hepatic fat accumulation through the upregulation of TFEB-mediated lipophagy. | 2021 | Details |
| A03509 | 33977096 | Can J Gastroenterol Hepatol | NAFLD and Infection, a Nuanced Relationship. | 2021 | Details |
| A03511 | 33975804 | Trends Endocrinol Metab | Links between metabolic syndrome and metabolic dysfunction-associated fatty liver disease. | 2021 | Details |
| A03515 | 33974725 | Phytother Res | Effects of garlic powder supplementation on metabolic syndrome components, insulin resistance, fatty liver index, and appetite in subjects with metabolic syndrome: A randomized clinical trial. | 2021 | Details |
| A03522 | 33971815 | BMC Gastroenterol | Normalization of γ-glutamyl transferase levels is associated with better metabolic control in individuals with nonalcoholic fatty liver disease. | 2021 | Details |
| A03526 | 33969054 | World J Clin Cases | Polycystic ovary syndrome: Pathways and mechanisms for possible increased susceptibility to COVID-19. | 2021 | Details |
| A03527 | 33967948 | Front Endocrinol (Lausanne) | Non-Alcoholic Fatty Liver Disease and Hypokalemia in Primary Aldosteronism Among Chinese Population. | 2021 | Details |
| A03531 | 33966916 | Arch Med Res | Hepatic Accumulation of Hypoxanthine: A Link Between Hyperuricemia and Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03535 | 33965533 | J Nutr Biochem | Toll-like receptor 3 ablation prevented high-fat diet-induced obesity and metabolic disorder. | 2021 | Details |
| A03542 | 33962276 | Ecotoxicol Environ Saf | Copper exposure association with prevalence of non-alcoholic fatty liver disease and insulin resistance among US adults (NHANES 2011-2014). | 2021 | Details |
| A03552 | 33960110 | Obes Rev | Effect of exercise on cardiometabolic health of adults with overweight or obesity: Focus on blood pressure, insulin resistance, and intrahepatic fat-A systematic review and meta-analysis. | 2021 | Details |
| A03564 | 33952843 | Nihon Yakurigaku Zasshi | [The roles of gap junctional intercellular communication in non-alcoholic steatohepatitis (NASH) and liver fibrosis]. | 2021 | Details |
| A03567 | 33951744 | Andrologia | Predicting risk of erectile dysfunction in patients with nonalcoholic fatty liver disease. | 2021 | Details |
| A03574 | 33948068 | Ann Gastroenterol | Effectiveness of dietary interventions on cardio-metabolic risk factors in patients with nonalcoholic fatty liver disease: a systematic review and meta-analysis of randomized controlled trials. | 2021 | Details |
| A03579 | 33946843 | Microorganisms | Gut Microbiota and NAFLD: Pathogenetic Mechanisms, Microbiota Signatures, and Therapeutic Interventions. | 2021 | Details |
| A03583 | 33943028 | J Diabetes Investig | Liver fibrosis is independently associated with diabetic peripheral neuropathy in type 2 diabetes mellitus. | 2021 | Details |
| A03584 | 33942524 | Pediatr Obes | Association between ectopic pancreatic and hepatic fat and metabolic risk factors in children with non-alcoholic fatty liver disease. | 2021 | Details |
| A03585 | 33941551 | BMJ Open Diabetes Res Care | Insulin resistance and liver histopathology in metabolically unhealthy subjects do not correlate with the hepatic abundance of NLRP3 inflammasome nor circulating IL-1β levels. | 2021 | Details |
| A03590 | 33939383 | Clin Transl Gastroenterol | Moderate-Intensity Aerobic vs Resistance Exercise and Dietary Modification in Patients With Nonalcoholic Fatty Liver Disease: A Randomized Clinical Trial. | 2021 | Details |
| A03602 | 33935810 | Front Physiol | Serum Creatinine-to-Cystatin C Ratio in the Progression Monitoring of Non-alcoholic Fatty Liver Disease. | 2021 | Details |
| A03606 | 33933462 | Exp Neurol | Liver inflammation at the time of spinal cord injury enhances intraspinal pathology, liver injury, metabolic syndrome and locomotor deficits. | 2021 | Details |
| A03622 | 33926132 | Metabolites | Dietary Macronutrient Composition Differentially Modulates the Remodeling of Mitochondrial Oxidative Metabolism during NAFLD. | 2021 | Details |
| A03629 | 33924909 | Diagnostics (Basel) | Liver Fibrosis and Steatosis in Alström Syndrome: A Genetic Model for Metabolic Syndrome. | 2021 | Details |
| A03630 | 33924725 | Nutrients | The Combination of Berberine, Tocotrienols and Coffee Extracts Improves Metabolic Profile and Liver Steatosis by the Modulation of Gut Microbiota and Hepatic miR-122 and miR-34a Expression in Mice. | 2021 | Details |
| A03633 | 33923817 | Int J Mol Sci | Role of Insulin Resistance in MAFLD. | 2021 | Details |
| A03635 | 33923525 | Nutrients | The Role of Fructose in Non-Alcoholic Steatohepatitis: Old Relationship and New Insights. | 2021 | Details |
| A03637 | 33923295 | Int J Mol Sci | Mitochondrial Mutations and Genetic Factors Determining NAFLD Risk. | 2021 | Details |
| A03639 | 33923175 | Cells | Adipocyte, Immune Cells, and miRNA Crosstalk: A Novel Regulator of Metabolic Dysfunction and Obesity. | 2021 | Details |
| A03649 | 33920751 | Metabolites | Presence and Implications of Sarcopenia in Non-alcoholic Steatohepatitis. | 2021 | Details |
| A03651 | 33919415 | Antioxidants (Basel) | Lyophilized Maqui (Aristotelia chilensis) Berry Administration Suppresses High-Fat Diet-Induced Liver Lipogenesis through the Induction of the Nuclear Corepressor SMILE. | 2021 | Details |
| A03665 | 33915261 | J Nutr Biochem | Consumption of soybean or olive oil at recommended concentrations increased the intestinal microbiota diversity and insulin sensitivity and prevented fatty liver compared to the effects of coconut oil. | 2021 | Details |
| A03670 | 33912410 | Tzu Chi Med J | Role of diet and lifestyle modification in the management of nonalcoholic fatty liver disease and type 2 diabetes. | 2020 | Details |
| A03674 | 33909947 | Mol Nutr Food Res | Effects of Insoluble Cereal Fibre on Body Fat Distribution in the Optimal Fibre Trial. | 2021 | Details |
| A03677 | 33907839 | Int J Mol Med | Role of 2‑series prostaglandins in the pathogenesis of type 2 diabetes mellitus and non‑alcoholic fatty liver disease (Review). | 2021 | Details |
| A03688 | 33901779 | Ecotoxicol Environ Saf | Dysregulation of autophagy acts as a pathogenic mechanism of non-alcoholic fatty liver disease (NAFLD) induced by common environmental pollutants. | 2021 | Details |
| A03700 | 33898960 | JHEP Rep | Treatment of NAFLD with intermittent calorie restriction or low-carb high-fat diet - a randomised controlled trial. | 2021 | Details |
| A03702 | 33898958 | JHEP Rep | Weight-loss-independent benefits of exercise on liver steatosis and stiffness in Japanese men with NAFLD. | 2021 | Details |
| A03703 | 33897617 | Front Endocrinol (Lausanne) | Mining Gut Microbiota From Bariatric Surgery for MAFLD. | 2021 | Details |
| A03704 | 33897616 | Front Endocrinol (Lausanne) | Glucagon-Like Peptide-1 Receptor Agonists for Non-Alcoholic Fatty Liver Disease in Type 2 Diabetes: A Meta-Analysis. | 2021 | Details |
| A03710 | 33895552 | Biochem Biophys Res Commun | The PDE5 inhibitor udenafil ameliorates nonalcoholic fatty liver disease by improving mitochondrial function. | 2021 | Details |
| A03715 | 33894178 | Am J Pathol | Inhibition of Estrogen-Related Receptor α Blocks Liver Steatosis and Steatohepatitis and Attenuates Triglyceride Biosynthesis. | 2021 | Details |
| A03720 | 33893355 | Sci Rep | Liver fat scores do not reflect interventional changes in liver fat content induced by high-protein diets. | 2021 | Details |
| A03722 | 33892169 | Mol Metab | Metabolic-associated fatty liver disease and lipoprotein metabolism. | 2021 | Details |
| A03727 | 33889132 | Front Endocrinol (Lausanne) | Non-Alcoholic Fatty Liver Disease in Obese Youth With Insulin Resistance and Type 2 Diabetes. | 2021 | Details |
| A03729 | 33887577 | Int Immunopharmacol | Neutrophil: An emerging player in the occurrence and progression of metabolic associated fatty liver disease. | 2021 | Details |
| A03733 | 33885048 | Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub | Effect of bariatric surgery on fatty liver disease in obese patients: A prospective one year follow-up study. | 2021 | Details |
| A03734 | 33883996 | Int J Endocrinol | Circulating Prokineticin 2 Levels Are Increased in Children with Obesity and Correlated with Insulin Resistance. | 2021 | Details |
| A03736 | 33883616 | Sci Rep | Non-alcoholic fatty liver disease is associated with bacterial translocation and a higher inflammation response in psoriatic patients. | 2021 | Details |
| A03737 | 33883445 | Curr Opin Lipidol | Nonalcohol fatty liver disease: balancing supply and utilization of triglycerides. | 2021 | Details |
| A03738 | 33883285 | Endocr Connect | Activation of heat shock response improves biomarkers of NAFLD in patients with metabolic diseases. | 2021 | Details |
| A03743 | 33880813 | Phytother Res | Effect of Portulaca Oleracea (purslane) extract on liver enzymes, lipid profile, and glycemic status in nonalcoholic fatty liver disease: A randomized, double-blind clinical trial. | 2021 | Details |
| A03749 | 33878988 | Expert Rev Gastroenterol Hepatol | Liver-spleen axis in nonalcoholic fatty liver disease. | 2021 | Details |
| A03750 | 33878875 | Arch Iran Med | Hepatic Steatosis and Fibrosis in Type 2 Diabetes: A Risk-Based Approach to Targeted Screening. | 2021 | Details |
| A03753 | 33877366 | Diabetologia | Liver-targeting drugs and their effect on blood glucose and hepatic lipids. | 2021 | Details |
| A03755 | 33876811 | Food Funct | The role of iron homeostasis in adipocyte metabolism. | 2021 | Details |
| A03758 | 33872860 | Mol Metab | Iron aggravates hepatic insulin resistance in the absence of inflammation in a novel db/db mouse model with iron overload. | 2021 | Details |
| A03765 | 33871240 | J Sports Med Phys Fitness | The effect of combined exercises on the plasma levels of retinol-binding protein 4 and its relationship with insulin resistance and hepatic fat content in postmenopausal women with nonalcoholic fatty liver disease. | 2021 | Details |
| A03776 | 33867442 | Eur J Gastroenterol Hepatol | Small intestinal bacterial overgrowth and orocecal transit time in patients of nonalcoholic fatty liver disease. | 2021 | Details |
| A03782 | 33865898 | Metabolism | Collagen β(1-O) galactosyltransferase 2 deficiency contributes to lipodystrophy and aggravates NAFLD related to HMW adiponectin in mice. | 2021 | Details |
| A03785 | 33864798 | Metabolism | Non-alcoholic fatty liver disease, insulin resistance, metabolic syndrome and their association with vascular risk. | 2021 | Details |
| A03789 | 33862461 | Biochem Biophys Res Commun | Canagliflozin ameliorates hepatic fat deposition in obese diabetic mice: Role of prostaglandin E2. | 2021 | Details |
| A03794 | 33862045 | Metabolism | Determinants of hepatic insulin clearance - Results from a Mendelian Randomization study. | 2021 | Details |
| A03797 | 33861444 | Adv Exp Med Biol | Medicinal Plants and Phytochemicals Regulating Insulin Resistance and Glucose Homeostasis in Type 2 Diabetic Patients: A Clinical Review. | 2021 | Details |
| A03798 | 33861434 | Adv Exp Med Biol | The Effect of Curcumin Phytosome on the Treatment of Patients with Non-alcoholic Fatty Liver Disease: A Double-Blind, Randomized, Placebo-Controlled Trial. | 2021 | Details |
| A03800 | 33860630 | FEBS J | Liver macrophages and inflammation in physiology and physiopathology of non-alcoholic fatty liver disease. | 2021 | Details |
| A03803 | 33860199 | ACS Pharmacol Transl Sci | Peripherally Selective CB1 Receptor Antagonist Improves Symptoms of Metabolic Syndrome in Mice. | 2021 | Details |
| A03804 | 33860188 | ACS Pharmacol Transl Sci | Pyruvate Dehydrogenase as a Therapeutic Target for Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03807 | 33860117 | Hepatol Commun | Lipoprotein Insulin Resistance Index Reflects Liver Fat Content in Patients With Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A03811 | 33860093 | JGH Open | Non-alcoholic fatty liver disease in premenopausal women with polycystic ovary syndrome: A systematic review and meta-analysis. | 2021 | Details |
| A03815 | 33859314 | Sci Rep | Extra virgin olive oil improved body weight and insulin sensitivity in high fat diet-induced obese LDLr-/-.Leiden mice without attenuation of steatohepatitis. | 2021 | Details |
| A03819 | 33857552 | Adv Drug Deliv Rev | Cellular protein markers, therapeutics, and drug delivery strategies in the treatment of diabetes-associated liver fibrosis. | 2021 | Details |
| A03829 | 33855386 | Minerva Endocrinol (Torino) | Relationship between plasma 12,13-diHOME level and nonalcoholic fatty liver disease in patients with type 2 diabetes and obesity. | 2021 | Details |
| A03842 | 33851592 | Wiad Lek | THE ROLE OF ZONULIN IN THE DEVELOPMENT OF LIVER FIBROSIS IN OBESE ADOLESCENTS. | 2021 | Details |
| A03860 | 33841814 | Food Sci Nutr | Functional beverages improve insulin resistance and hepatic steatosis modulating lysophospholipids in diet-induced obese rats. | 2021 | Details |
| A03864 | 33840072 | Curr Obes Rep | The Role of Mitochondrial Adaptation and Metabolic Flexibility in the Pathophysiology of Obesity and Insulin Resistance: an Updated Overview. | 2021 | Details |
| A03865 | 33839905 | Eur J Nutr | Improving insulin sensitivity, liver steatosis and fibrosis in type 2 diabetes by a food-based digital education-assisted lifestyle intervention program: a feasibility study. | 2021 | Details |
| A03869 | 33838673 | Nutr J | Effects of supplementation with main coffee components including caffeine and/or chlorogenic acid on hepatic, metabolic, and inflammatory indices in patients with non-alcoholic fatty liver disease and type 2 diabetes: a randomized, double-blind, placebo-controlled, clinical trial. | 2021 | Details |
| A03874 | 33837670 | Liver Transpl | Atherogenic Dyslipidemia After Liver Transplantation: Mechanisms and Clinical Implications. | 2021 | Details |
| A03881 | 33833974 | Pediatr Gastroenterol Hepatol Nutr | Vitamin D Effect on Ultrasonography and Laboratory Indices and Biochemical Indicators in the Blood: an Interventional Study on 12 to 18-Year-Old Children with Fatty Liver. | 2021 | Details |
| A03892 | 33831474 | Adv Drug Deliv Rev | Lipid based nanocarriers for effective drug delivery and treatment of diabetes associated liver fibrosis. | 2021 | Details |
| A03893 | 33830112 | Mymensingh Med J | Study on Alanine Aminotransferase in Patients of Type 2 Diabetes Mellitus. | 2021 | Details |
| A03908 | 33823088 | J Pediatr Endocrinol Metab | Early menarche is associated with insulin-resistance and non-alcoholic fatty liver disease in adolescents with obesity. | 2021 | Details |
| A03910 | 33822497 | Int J Med Mushrooms | Bioactive Components and Possible Activities of Medicinal Mushrooms in Alleviating the Pathogenesis of Nonalcoholic Fatty Liver Disease (Review). | 2021 | Details |
| A03912 | 33822104 | J Pharm Pharmacol | Eugenol modulates insulin sensitivity by upregulating insulin receptor substrate-2 in non-alcoholic fatty liver disease in rats. | 2021 | Details |
| A03915 | 33820503 | Mini Rev Med Chem | Mechanism of Natural Drugs on Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03918 | 33818349 | Nutr Res Rev | Effects of betaine on non-alcoholic liver disease. | 2021 | Details |
| A03935 | 33813276 | Biochem Biophys Res Commun | Hepatocytes derived increased SAA1 promotes intrahepatic platelet aggregation and aggravates liver inflammation in NAFLD. | 2021 | Details |
| A03939 | 33811619 | Eat Weight Disord | Association of obstructive sleep apnea with non-alcoholic fatty liver disease in patients with obesity: an observational study. | 2021 | Details |
| A03942 | 33811367 | Hepatology | Saroglitazar, a PPAR-α/γ Agonist, for Treatment of NAFLD: A Randomized Controlled Double-Blind Phase 2 Trial. | 2021 | Details |
| A03947 | 33810566 | Int J Mol Sci | Hepatic Senescence Accompanies the Development of NAFLD in Non-Aged Mice Independently of Obesity. | 2021 | Details |
| A03952 | 33809593 | Nutrients | Fortifying Butterfat with Soybean Oil Attenuates the Onset of Diet-Induced Non-Alcoholic Steatohepatitis and Glucose Intolerance. | 2021 | Details |