Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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oxidative stress3585 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A06183 | 32977490 | Cells | The Absence of NLRP3-inflammasome Modulates Hepatic Fibrosis Progression, Lipid Metabolism, and Inflammation in KO NLRP3 Mice during Aging. | 2020 | Details |
| A06187 | 32976958 | Toxicology | Study on the attenuated effect of Ginkgolide B on ferroptosis in high fat diet induced nonalcoholic fatty liver disease. | 2020 | Details |
| A06207 | 32967529 | RNA Biol | Comprehensive analysis of the translatome reveals the relationship between the translational and transcriptional control in high fat diet-induced liver steatosis. | 2020 | Details |
| A06212 | 32965675 | Hepatology | Activating Adenosine Monophosphate-Activated Protein Kinase Mediates Fibroblast Growth Factor 1 Protection From Nonalcoholic Fatty Liver Disease in Mice. | 2021 | Details |
| A06223 | 32963259 | Sci Rep | Mechanistic study of attenuation of monosodium glutamate mixed high lipid diet induced systemic damage in rats by Coccinia grandis. | 2020 | Details |
| A06247 | 32952872 | World J Hepatol | Lipidomics in non-alcoholic fatty liver disease. | 2020 | Details |
| A06256 | 32951715 | Complement Ther Med | The effect of melatonin on treatment of patients with non-alcoholic fatty liver disease: a randomized double blind clinical trial. | 2020 | Details |
| A06283 | 32942773 | Molecules | New Perspectives of S-Adenosylmethionine (SAMe) Applications to Attenuate Fatty Acid-Induced Steatosis and Oxidative Stress in Hepatic and Endothelial Cells. | 2020 | Details |
| A06289 | 32940033 | J Agric Food Chem | (-)-Hydroxycitric Acid Alleviates Oleic Acid-Induced Steatosis, Oxidative Stress, and Inflammation in Primary Chicken Hepatocytes by Regulating AMP-Activated Protein Kinase-Mediated Reactive Oxygen Species Levels. | 2020 | Details |
| A06295 | 32937687 | Clin Mol Hepatol | Obesity and binge alcohol intake are deadly combination to induce steatohepatitis: A model of high-fat diet and binge ethanol intake. | 2020 | Details |
| A06303 | 32935743 | Arq Gastroenterol | DISTINCT PHENOTYPE OF NON-ALCOHOLIC FATTY LIVER DISEASE IN PATIENTS WITH LOW LEVELS OF FREE COPPER AND OF CERULOPLASMIN. | 2021 | Details |
| A06309 | 32933722 | Tissue Cell | Liraglutide in combination with human umbilical cord mesenchymal stem cell could improve liver lesions by modulating TLR4/NF-kB inflammatory pathway and oxidative stress in T2DM/NAFLD rats. | 2020 | Details |
| A06316 | 32932174 | J Trace Elem Med Biol | The effects of zinc supplementation on metabolic profile and oxidative stress in overweight/obese patients with non-alcoholic fatty liver disease: A randomized, double-blind, placebo-controlled trial. | 2020 | Details |
| A06327 | 32927776 | Nutrients | New Insights into the Pathogenesis of Non-Alcoholic Fatty Liver Disease: Gut-Derived Lipopolysaccharides and Oxidative Stress. | 2020 | Details |
| A06348 | 32920226 | Redox Biol | Vitamin E treatment in NAFLD patients demonstrates that oxidative stress drives steatosis through upregulation of de-novo lipogenesis. | 2020 | Details |
| A06354 | 32918763 | FASEB J | Branched chain amino acids and carbohydrate restriction exacerbate ketogenesis and hepatic mitochondrial oxidative dysfunction during NAFLD. | 2020 | Details |
| A06362 | 32916011 | Liver Transpl | Monoacylglycerol Acyltransferase 1 Knockdown Exacerbates Hepatic Ischemia/Reperfusion Injury in Mice With Hepatic Steatosis. | 2020 | Details |
| A06365 | 32914125 | Curr Res Food Sci | Piceatannol attenuates fat accumulation and oxidative stress in steatosis-induced HepG2 cells. | 2020 | Details |
| A06383 | 32903892 | Clin Exp Gastroenterol | Prevalence and Risk Factors of Hyperuricemia in Patients with Chronic Kidney Disease and Non-Alcoholic Fatty Liver. | 2020 | Details |
| A06386 | 32900489 | Biochem Biophys Res Commun | Adrenic acid induces oxidative stress in hepatocytes. | 2020 | Details |
| A06394 | 32896622 | Biochim Biophys Acta Mol Cell Biol Lipids | 12α-Hydroxylated bile acid induces hepatic steatosis with dysbiosis in rats. | 2020 | Details |
| A06405 | 32891697 | Biochimie | Treatments in Covid-19 patients with pre-existing metabolic dysfunction-associated fatty liver disease: A potential threat for drug-induced liver injury? | 2020 | Details |
| A06440 | 32880477 | Arch Physiol Biochem | High sugar but not high fat diet consumption induces hepatic metabolic disruption and up-regulation of mitochondrial fission-associated protein Drp1 in a model of moderate obesity. | 2020 | Details |
| A06444 | 32879962 | Adv Nutr | A Comprehensive Systematic Review of the Effects of Naringenin, a Citrus-Derived Flavonoid, on Risk Factors for Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A06463 | 32870526 | J Gastroenterol Hepatol | Oxidative stress and Liver X Receptor agonist induce hepatocellular carcinoma in Non-alcoholic steatohepatitis model. | 2020 | Details |
| A06473 | 32865925 | Int J Med Mushrooms | Pharmacological Investigation of Ceraceomyces tessulatus (Agaricomycetes) in Mice with Nonalcoholic Steatohepatitis. | 2020 | Details |
| A06474 | 32865911 | Crit Rev Oncog | Role of the Gut Microbiome in Nonalcoholic Fatty Liver Disease Progression. | 2020 | Details |
| A06479 | 32863886 | BioData Min | Network pharmacology reveals the multiple mechanisms of Xiaochaihu decoction in the treatment of non-alcoholic fatty liver disease. | 2020 | Details |
| A06492 | 32856322 | J Pharm Pharmacol | Therapeutic effects of açaí seed extract on hepatic steatosis in high-fat diet-induced obesity in male mice: a comparative effect with rosuvastatin. | 2020 | Details |
| A06503 | 32849935 | J Clin Med Res | Non-Alcoholic Fatty Liver Disease Modifies Serum Gamma-Glutamyl Transferase in Cigarette Smokers. | 2020 | Details |
| A06510 | 32848877 | Front Physiol | Neurotropin Inhibits Lipid Accumulation by Maintaining Mitochondrial Function in Hepatocytes via AMPK Activation. | 2020 | Details |
| A06561 | 32824723 | Int J Mol Sci | Hypothyroidism-Induced Nonalcoholic Fatty Liver Disease (HIN): Mechanisms and Emerging Therapeutic Options. | 2020 | Details |
| A06563 | 32824349 | Antioxidants (Basel) | Oxidative Stress and Pro-Inflammatory Status in Patients with Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A06575 | 32822323 | Orv Hetil | New aspects of the development of liver diseases – with special regard to the role of autophagy and microRNA | 2020 | Details |
| A06589 | 32818435 | Cell Metab | Triose Kinase Controls the Lipogenic Potential of Fructose and Dietary Tolerance. | 2020 | Details |
| A06606 | 32810635 | Free Radic Biol Med | Lower adropin expression is associated with oxidative stress and severity of nonalcoholic fatty liver disease. | 2020 | Details |
| A06609 | 32810309 | J Gastroenterol Hepatol | Systematic review with meta-analysis: The effect of vitamin E supplementation in adult patients with non-alcoholic fatty liver disease. | 2020 | Details |
| A06618 | 32805401 | Free Radic Biol Med | Cyanidin-3-O-β-glucoside inactivates NLRP3 inflammasome and alleviates alcoholic steatohepatitis via SirT1/NF-κB signaling pathway. | 2020 | Details |
| A06619 | 32805210 | Chem Biol Interact | High fat diet-triggered non-alcoholic fatty liver disease: A review of proposed mechanisms. | 2020 | Details |
| A06622 | 32804855 | Eur J Gastroenterol Hepatol | Chromium picolinate balances the metabolic and clinical markers in nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled trial. | 2021 | Details |
| A06639 | 32798261 | Phytother Res | The effect of saffron supplementation on some inflammatory and oxidative markers, leptin, adiponectin, and body composition in patients with nonalcoholic fatty liver disease: A double-blind randomized clinical trial. | 2020 | Details |
| A06649 | 32795119 | Metab Syndr Relat Disord | Omeprazole and Spirulina Platensis Ameliorate Steatohepatitis in Experimental Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A06668 | 32786869 | J Agric Food Chem | Combined Effect of Quercetin and Fish Oil on Oxidative Stress in the Liver of Mice Fed a Western-Style Diet. | 2020 | Details |
| A06670 | 32786176 | Zool Res | Assessment of mitochondrial function in metabolic dysfunction-associated fatty liver disease using obese mouse models. | 2020 | Details |
| A06704 | 32775098 | Cureus | Vitamin E as an Adjuvant Treatment for Non-alcoholic Fatty Liver Disease in Adults: A Systematic Review of Randomized Controlled Trials. | 2020 | Details |
| A06708 | 32774420 | Evid Based Complement Alternat Med | Anti-inflammatory Mechanism of Ruzu Bitters on Diet-Induced Nonalcoholic Fatty Liver Disease in Male Wistar Rats. | 2020 | Details |
| A06713 | 32772909 | Comb Chem High Throughput Screen | Evaluation of Insulin Resistance Induced Brain Tissue Dysfunction in Obese Dams and their Neonates: Role of Ipriflavone Amelioration. | 2021 | Details |
| A06730 | 32766475 | Hepatol Commun | Lack of Augmenter of Liver Regeneration Disrupts Cholesterol Homeostasis of Liver in Mice by Inhibiting the AMPK Pathway. | 2020 | Details |
| A06739 | 32765301 | Front Physiol | Lipophagy Impairment Is Associated With Disease Progression in NAFLD. | 2020 | Details |
| A06752 | 32759852 | Int J Mol Sci | Effective Combination Therapy of Angiotensin-II Receptor Blocker and Rifaximin for Hepatic Fibrosis in Rat Model of Nonalcoholic Steatohepatitis. | 2020 | Details |
| A06753 | 32759548 | Biol Pharm Bull | Amelioration of the Lipogenesis, Oxidative Stress and Apoptosis of Hepatocytes by a Novel Proteoglycan from Ganoderma lucidum. | 2020 | Details |
| A06756 | 32758573 | Eur J Pharmacol | Gut microbiota modulation as a promising therapy with metformin in rats with non-alcoholic steatohepatitis: Role of LPS/TLR4 and autophagy pathways. | 2020 | Details |
| A06759 | 32757283 | Fundam Clin Pharmacol | Protective effect of fenofibrate against high-fat-high-fructose diet induced non-obese NAFLD in rats. | 2020 | Details |
| A06773 | 32751983 | Biomolecules | Arachidonic Acid as an Early Indicator of Inflammation during Non-Alcoholic Fatty Liver Disease Development. | 2020 | Details |
| A06786 | 32746645 | Expert Rev Gastroenterol Hepatol | Clinical heterogeneity in patients with non-alcoholic fatty liver disease-associated hepatocellular carcinoma. | 2020 | Details |
| A06791 | 32744348 | J Food Biochem | Biochemical and histopathological assessment of liver in a rat model of metabolic syndrome induced by high-carbohydrate high-fat diet. | 2020 | Details |
| A06806 | 32738398 | Free Radic Biol Med | Generation of sphingosine-1-phosphate by sphingosine kinase 1 protects nonalcoholic fatty liver from ischemia/reperfusion injury through alleviating reactive oxygen species production in hepatocytes. | 2020 | Details |
| A06820 | 32734608 | J Pharm Pharmacol | HWL-088, a new and highly effective FFA1/PPARδ dual agonist, attenuates nonalcoholic steatohepatitis by regulating lipid metabolism, inflammation and fibrosis. | 2020 | Details |
| A06822 | 32734012 | Porto Biomed J | An albino mouse model of nonalcoholic fatty liver disease induced using high-fat liquid "Lieber-DeCarli" diet: a preliminary investigation. | 2020 | Details |
| A06861 | 32719069 | J Pharmacol Exp Ther | The GPR40 Full Agonist SCO-267 Improves Liver Parameters in a Mouse Model of Nonalcoholic Fatty Liver Disease without Affecting Glucose or Body Weight. | 2020 | Details |
| A06862 | 32718371 | Br J Nutr | Lactobacillus casei YRL577 ameliorates markers of non-alcoholic fatty liver and alters expression of genes within the intestinal bile acid pathway. | 2020 | Details |
| A06863 | 32718364 | Br J Nutr | Lactobacillus casei YRL577 combined with plant extracts reduce markers of non-alcoholic fatty liver disease in mice. | 2020 | Details |
| A06877 | 32712601 | Aging (Albany NY) | Decreased autophagy and fuel switching occur in a senescent hepatic cell model system. | 2020 | Details |
| A06918 | 32698063 | Int J Biol Macromol | Effects of surface-deacetylated chitin nanofibers on non-alcoholic steatohepatitis model rats and their gut microbiota. | 2020 | Details |
| A06919 | 32698042 | Cell Mol Gastroenterol Hepatol | Impaired Hepatic Vitamin A Metabolism in NAFLD Mice Leading to Vitamin A Accumulation in Hepatocytes. | 2020 | Details |
| A06977 | 32679195 | Arch Biochem Biophys | (-)-Epicatechin and the comorbidities of obesity. | 2020 | Details |
| A06980 | 32677680 | Clin Sci (Lond) | Non-alcoholic fatty liver disease: a metabolic burden promoting atherosclerosis. | 2020 | Details |
| A06986 | 32671767 | Adv Exp Med Biol | Autophagy and Obesity and Diabetes. | 2020 | Details |
| A06990 | 32670822 | J Tradit Complement Med | The synergistic effect of Citrus bergamia and Cynara cardunculus extracts on vascular inflammation and oxidative stress in non-alcoholic fatty liver disease. | 2020 | Details |
| A06991 | 32670821 | J Tradit Complement Med | Beneficial effects of Chinese herbs in the treatment of fatty liver diseases. | 2020 | Details |
| A06996 | 32666969 | Food Funct | Ameliorative effects and molecular mechanisms of vine tea on western diet-induced NAFLD. | 2020 | Details |
| A07001 | 32664383 | Antioxidants (Basel) | The Interplay between Oxidative Stress and miRNAs in Obesity-Associated Hepatic and Vascular Complications. | 2020 | Details |
| A07004 | 32663612 | Ann Hepatol | Mediterranean-like mix of fatty acids induces cellular protection on lipid-overloaded hepatocytes from western diet fed mice. | 2020 | Details |
| A07016 | 32655764 | Oxid Med Cell Longev | Gentiopicroside Ameliorates Oxidative Stress and Lipid Accumulation through Nuclear Factor Erythroid 2-Related Factor 2 Activation. | 2020 | Details |
| A07051 | 32640454 | Pharmacology | Molecular Study on the Potential Protective Effects of Bee Venom against Fructose-Induced Nonalcoholic Steatohepatitis in Rats. | 2020 | Details |
| A07067 | 32634278 | J Intern Med | Liver mitochondrial DNA damage and genetic variability of Cytochrome b - a key component of the respirasome - drive the severity of fatty liver disease. | 2020 | Details |
| A07076 | 32630732 | Antioxidants (Basel) | Serum Malondialdehyde is Associated with Non-Alcoholic Fatty Liver and Related Liver Damage Differentially in Men and Women. | 2020 | Details |
| A07078 | 32630596 | Int J Mol Sci | SGL 121 Attenuates Nonalcoholic Fatty Liver Disease through Adjusting Lipid Metabolism Through AMPK Signaling Pathway. | 2020 | Details |
| A07093 | 32626560 | Middle East J Dig Dis | Assessment of Genetic Aspects of Non-alcoholic Fatty Liver and Premature Cardiovascular Events. | 2020 | Details |
| A07100 | 32622362 | J Neuroinflammation | Lipocalin 2 induces neuroinflammation and blood-brain barrier dysfunction through liver-brain axis in murine model of nonalcoholic steatohepatitis. | 2020 | Details |
| A07107 | 32621046 | Cardiovasc Drugs Ther | Prolonged-release pirfenidone prevents obesity-induced cardiac steatosis and fibrosis in a mouse NASH model. | 2021 | Details |
| A07109 | 32620521 | Dig Liver Dis | Suppression of high-fat diet-induced obesity-associated liver mitochondrial dysfunction by docosahexaenoic acid and hydroxytyrosol co-administration. | 2020 | Details |
| A07126 | 32612827 | SAGE Open Med | Nonalcoholic fatty liver disease and cardiovascular disease phenotypes. | 2020 | Details |
| A07131 | 32608271 | Arch Physiol Biochem | Improvement of thiol groups and total antioxidant capacity in patients with non-alcoholic fatty liver after treatment with pioglitazone. | 2020 | Details |
| A07141 | 32605253 | Cancers (Basel) | Current and Future Treatments in the Fight Against Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A07142 | 32604760 | Nutrients | Selenoneine Ameliorates Hepatocellular Injury and Hepatic Steatosis in a Mouse Model of NAFLD. | 2020 | Details |
| A07150 | 32599319 | Int Immunopharmacol | Potential anti-inflammatory effect of dapagliflozin in HCHF diet- induced fatty liver degeneration through inhibition of TNF-α, IL-1β, and IL-18 in rat liver. | 2020 | Details |
| A07157 | 32597705 | Am J Physiol Gastrointest Liver Physiol | Mitochondrial oxidative injury: a key player in nonalcoholic fatty liver disease. | 2020 | Details |
| A07174 | 32592770 | Eur J Pharmacol | Hepatoprotective effects of ZLY16, a dual peroxisome proliferator-activated receptor α/δ agonist, in rodent model of nonalcoholic steatohepatitis. | 2020 | Details |
| A07188 | 32589264 | Eur J Clin Invest | COVID-19 and non-alcoholic fatty liver disease: Two intersecting pandemics. | 2020 | Details |
| A07196 | 32586422 | Reprod Fertil Dev | Ovulation mitigates fatty liver associated with reproductive suppression and oxidative stress in Damaraland mole-rats (Fukomys damarensis). | 2020 | Details |
| A07210 | 32581811 | Front Pharmacol | Untargeted Metabolomic Analysis of the Effects and Mechanism of Nuciferine Treatment on Rats With Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A07215 | 32579743 | Mol Nutr Food Res | Fat-Shaped Microbiota Affects Lipid Metabolism, Liver Steatosis, and Intestinal Homeostasis in Mice Fed a Low-Protein Diet. | 2020 | Details |
| A07219 | 32577775 | Inflamm Res | Pathobiological and molecular connections involved in the high fructose and high fat diet induced diabetes associated nonalcoholic fatty liver disease. | 2020 | Details |
| A07244 | 32569680 | Metabolism | Metabolic liver disease in diabetes - From mechanisms to clinical trials. | 2020 | Details |
| A07250 | 32566571 | Ann Transl Med | Association between ratio of γ-glutamyl transpeptidase to high-density lipoprotein cholesterol and prevalence of nonalcoholic fatty liver disease and metabolic syndrome: a cross-sectional study. | 2020 | Details |
| A07251 | 32566547 | Can J Gastroenterol Hepatol | Effect of Melatonin as an Antioxidant Drug to Reverse Hepatic Steatosis: Experimental Model. | 2020 | Details |
| A07253 | 32566176 | Food Sci Nutr | Lycium ruthenicum Murr. alleviates nonalcoholic fatty liver in mice. | 2020 | Details |
| A07260 | 32562818 | Pharmacol Res | ZLY032, the first-in-class dual FFA1/PPARδ agonist, improves glucolipid metabolism and alleviates hepatic fibrosis. | 2020 | Details |
| A07269 | 32559586 | J Nutr Biochem | Citrus reticulata Blanco peel extract ameliorates hepatic steatosis, oxidative stress and inflammation in HF and MCD diet-induced NASH C57BL/6 J mice. | 2020 | Details |