Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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insulin resistance7794 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A46617 | 17268250 | Curr Opin Gastroenterol | Fatty liver and the metabolic syndrome. | 2007 | Details |
| A46618 | 17267845 | Obstet Gynecol | Management of obesity in pregnancy. | 2007 | Details |
| A46622 | 17244464 | Zhonghua Gan Zang Bing Za Zhi | [Association of nonalcoholic fatty liver disease with serum adiponectin and insulin resistance]. | 2007 | Details |
| A46626 | 17164118 | Clin Liver Dis | Role of obesity, insulin resistance, and steatosis in hepatitis C virus infection. | 2006 | Details |
| A46628 | 17145635 | Am J Clin Pathol | Biochemical markers: the road map for the diagnosis of nonalcoholic fatty liver disease. | 2007 | Details |
| A46629 | 17136797 | Mayo Clin Health Lett | Nonalcoholic fatty liver disease. A growing problem. | 2006 | Details |
| A46630 | 17114290 | Proc Natl Acad Sci U S A | Increased prevalence of insulin resistance and nonalcoholic fatty liver disease in Asian-Indian men. | 2006 | Details |
| A46632 | 17099068 | FASEB J | Resistance to leptin action is the major determinant of hepatic triglyceride accumulation in vivo. | 2006 | Details |
| A46640 | 16968796 | J Clin Endocrinol Metab | Serum resistin and hepatic fat content in nondiabetic individuals. | 2006 | Details |
| A46641 | 16952562 | Gastroenterology | Nonalcoholic fatty liver disease: Cytokine-adipokine interplay and regulation of insulin resistance. | 2006 | Details |
| A46644 | 16938178 | Zhonghua Gan Zang Bing Za Zhi | [Association between tumor necrosis factor-alpha gene polymorphism and insulin resistance in nonalcoholic fatty liver disease]. | 2006 | Details |
| A46645 | 16932311 | Nat Clin Pract Endocrinol Metab | Mechanisms of Disease: hepatic steatosis in type 2 diabetes--pathogenesis and clinical relevance. | 2006 | Details |
| A46647 | 16912555 | Curr Opin Clin Nutr Metab Care | Assessment of metabolic profile in a clinical setting. | 2006 | Details |
| A46648 | 16912127 | J Clin Endocrinol Metab | Alanine aminotransferase levels and fatty liver in childhood obesity: associations with insulin resistance, adiponectin, and visceral fat. | 2006 | Details |
| A46656 | 16825939 | J Clin Gastroenterol | Association of nonalcoholic fatty liver disease with abnormal aminotransferase and postprandial hyperglycemia. | 2006 | Details |
| A46657 | 16825675 | Am J Clin Nutr | Nonalcoholic fatty liver, nonalcoholic steatohepatitis, ectopic fat, and the glycemic index. | 2006 | Details |
| A46658 | 16799888 | J Gastroenterol | Visceral fat accumulation and insulin resistance are important factors in nonalcoholic fatty liver disease. | 2006 | Details |
| A46660 | 16774486 | Expert Opin Drug Saf | Ezetimibe: effective and safe treatment for dyslipidaemia associated with nonalcoholic fatty liver disease. Response to: Toth PP, Davidson MH: simvastatin and ezetimibe: combination therapy for the management of dyslipidaemia. Expert Opin. Pharmacother. (2005) 6(1):131-139. | 2006 | Details |
| A46661 | 16771968 | Am J Gastroenterol | Metformin, vitamin E, and diet for patients with nonalcoholic fatty liver disease. | 2006 | Details |
| A46663 | 16770927 | Am Fam Physician | Nonalcoholic fatty liver disease. | 2006 | Details |
| A46664 | 16767302 | Arq Bras Endocrinol Metabol | [Insulin resistance/hyperinsulinemia associated diseases not included in the metabolic syndrome]. | 2006 | Details |
| A46665 | 16762001 | Liver Int | Distinguishing nonalcoholic steatohepatitis from fatty liver: serum-free fatty acids, insulin resistance, and serum lipoproteins. | 2006 | Details |
| A46669 | 16729327 | Hepatology | Impact of obesity on treatment of chronic hepatitis C. | 2006 | Details |
| A46671 | 16708768 | Altern Ther Health Med | The add-on effects of Gynostemma pentaphyllum on nonalcoholic fatty liver disease. | 2006 | Details |
| A46674 | 16698763 | Gut | A new silybin-vitamin E-phospholipid complex improves insulin resistance and liver damage in patients with non-alcoholic fatty liver disease: preliminary observations. | 2006 | Details |
| A46680 | 16584696 | Gastroenterol Hepatol | [Epidemiology and natural history of primary nonalcoholic fatty liver disease]. | 2006 | Details |
| A46690 | 16510031 | Curr Gastroenterol Rep | New treatments for nonalcoholic fatty liver disease. | 2006 | Details |
| A46692 | 16489319 | Panminerva Med | Insulin resistance, the insulin resistance syndrome, and cardiovascular disease. | 2005 | Details |
| A46693 | 16478772 | Am J Physiol Endocrinol Metab | Liver steatosis coexists with myocardial insulin resistance and coronary dysfunction in patients with type 2 diabetes. | 2006 | Details |
| A46696 | 16460473 | J Gastroenterol Hepatol | Non-alcoholic fatty liver disease: the unfolding monster? | 2006 | Details |
| A46698 | 16444867 | Vasc Med | Insulin resistance: potential role of the endogenous nitric oxide synthase inhibitor ADMA. | 2005 | Details |
| A46708 | 16311087 | Metabolism | Hyperinsulinemia predicts hepatic fat content in healthy individuals with normal transaminase concentrations. | 2005 | Details |
| A46715 | 16265231 | Nat Clin Pract Gastroenterol Hepatol | Mechanisms of disease: adipocytokines and visceral adipose tissue--emerging role in nonalcoholic fatty liver disease. | 2005 | Details |
| A46721 | 16226915 | Hepatol Res | Role of suppressors of cytokine signaling SOCS-1 and SOCS-3 in hepatic steatosis and the metabolic syndrome. | 2005 | Details |
| A46726 | 16175602 | Hepatology | Steatohepatitis induced by intragastric overfeeding in mice. | 2005 | Details |
| A46730 | 16160540 | Curr Opin Pediatr | Nonalcoholic fatty liver disease in the pediatric population: a review. | 2005 | Details |
| A46738 | 16011474 | Annu Rev Nutr | Pediatric obesity and insulin resistance: chronic disease risk and implications for treatment and prevention beyond body weight modification. | 2005 | Details |
| A46742 | 15990591 | Curr Opin Lipidol | Nonalcoholic fatty liver disease and the metabolic syndrome. | 2005 | Details |
| A46743 | 15989845 | Med Clin (Barc) | [Medical management of primary nonalcoholic fatty liver disease]. | 2005 | Details |
| A46744 | 15989823 | Gastroenterol Hepatol | [Non-alcoholic fatty liver disease, serum iron indexes and iron concentration in the liver]. | 2005 | Details |
| A46751 | 15920084 | Diabetes Care | Second World Congress on the Insulin Resistance Syndrome: insulin resistance syndrome and nonalcoholic fatty liver disease. | 2005 | Details |
| A46752 | 15913829 | J Hepatol | Signalling links in the liver: knitting SOCS with fat and inflammation. | 2005 | Details |
| A46755 | 15882516 | Med Clin (Barc) | [Pathogenesis of primary nonalcoholic fatty liver disease]. | 2005 | Details |
| A46756 | 15855597 | Diabetes Care | Associations between liver histology and severity of the metabolic syndrome in subjects with nonalcoholic fatty liver disease. | 2005 | Details |
| A46757 | 15842599 | Am J Gastroenterol | The prevalence of autoantibodies and autoimmune hepatitis in patients with nonalcoholic fatty liver disease. | 2005 | Details |
| A46759 | 15810122 | Gastroenterology | Contribution of metabolic factors to alanine aminotransferase activity in persons with other causes of liver disease. | 2005 | Details |
| A46760 | 15795412 | CMAJ | Nonalcoholic fatty liver disease. | 2005 | Details |
| A46762 | 15779390 | Nihon Rinsho | [Impaired glucose tolerance in nonalcoholic fatty liver disease]. | 2005 | Details |
| A46765 | 15730035 | Ned Tijdschr Geneeskd | [Nonalcoholic steatohepatitis: diagnosis, pathogenesis, treatment and prognosis]. | 2005 | Details |
| A46771 | 15705403 | Fertil Steril | Abnormal aminotransferase activity in women with polycystic ovary syndrome. | 2005 | Details |
| A46773 | 15703606 | Curr Opin Gastroenterol | Innate immunity in the liver. | 2003 | Details |
| A46775 | 15682682 | J Investig Med | Oxidative stress in nonalcoholic fatty liver disease: pathogenesis and antioxidant therapies. | 2004 | Details |
| A46776 | 15670659 | Alcohol | Role of fatty liver, dietary fatty acid supplements, and obesity in the progression of alcoholic liver disease: introduction and summary of the symposium. | 2004 | Details |
| A46779 | 15632182 | J Biol Chem | Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling. | 2005 | Details |
| A46785 | 15598693 | J Clin Endocrinol Metab | Insulin resistance, the metabolic syndrome, and nonalcoholic fatty liver disease. | 2004 | Details |
| A46788 | 15547646 | Angiology | Prevention and treatment of the metabolic syndrome. | 2005 | Details |
| A46801 | 15331066 | Clin Liver Dis | Mitochondria in nonalcoholic fatty liver disease. | 2004 | Details |
| A46802 | 15262299 | Endocrinol Metab Clin North Am | Glitazones and the management of insulin resistance: what they do and how might they be used. | 2004 | Details |
| A46803 | 15254578 | J Clin Invest | Molecular mediators of hepatic steatosis and liver injury. | 2004 | Details |
| A46804 | 15240880 | Proc Natl Acad Sci U S A | Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse. | 2004 | Details |
| A46806 | 15195530 | Gastroenterol Hepatol | [Pathogenesis of non-alcoholic fatty liver and potential therapeutic targets]. | 2004 | Details |
| A46808 | 15151470 | Expert Rev Cardiovasc Ther | Treatment of metabolic syndrome. | 2004 | Details |
| A46809 | 15122714 | Ann Neurol | Valproate therapy and nonalcoholic fatty liver disease. | 2004 | Details |
| A46811 | 15051828 | J Nutr | Mice heterozygous for Atp10c, a putative amphipath, represent a novel model of obesity and type 2 diabetes. | 2004 | Details |
| A46814 | 14985206 | Am J Clin Nutr | Another animal model for nonalcoholic steatohepatitis: how close to the human condition? | 2004 | Details |
| A46817 | 14749503 | Recent Prog Horm Res | Obesity, insulin resistance, and cardiovascular disease. | 2004 | Details |
| A46820 | 14698985 | Endocr Pract | Insulin resistance syndrome and nonalcoholic fatty liver disease. | 2004 | Details |
| A46830 | 14499793 | Am J Gastroenterol | Current biochemical studies of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis suggest a new therapeutic approach. | 2003 | Details |
| A46833 | 12957298 | Alcohol | Iron as a co-morbid factor in nonhemochromatotic liver disease. | 2003 | Details |
| A46834 | 12920429 | Gastroenterol Nurs | Nonalcoholic Fatty liver disease. | 2003 | Details |
| A46843 | 12779071 | Dig Liver Dis | Increased susceptibility to nonalcoholic fatty liver disease in heterozygotes for the mutation responsible for hereditary hemochromatosis. | 2003 | Details |
| A46844 | 12768390 | J Gastroenterol | Serum leptin level can be a negative marker of hepatocyte damage in nonalcoholic fatty liver. | 2003 | Details |
| A46846 | 12648420 | Zhonghua Gan Zang Bing Za Zhi | [Current therapy strategies for nonalcoholic fatty liver disease]. | 2003 | Details |
| A46848 | 12648413 | Zhonghua Gan Zang Bing Za Zhi | [The role of improving insulin-resistant in the treatment and prevention of nonalcoholic fatty liver disease]. | 2003 | Details |
| A46879 | 11832442 | Gastroenterology | Tumor necrosis factor alpha promoter polymorphisms and insulin resistance in nonalcoholic fatty liver disease. | 2002 | Details |
| A46886 | 11360453 | Dtsch Med Wochenschr | [Nonalcoholic steatohepatitis: epidemiology, diagnosis and treatment]. | 2001 | Details |
| A46892 | 11296693 | Semin Liver Dis | Clinical features and natural history of nonalcoholic steatosis syndromes. | 2001 | Details |
| A46893 | 11293184 | Indian J Gastroenterol | Nonalcoholic steatohepatitis. | 2001 | Details |
| A46897 | 11032566 | Am J Med | Nonalcoholic fatty liver disease is associated with hyperlipidemia and obesity. | 2000 | Details |
| A47001 | 30721374 | Cell Biol Toxicol | Activation of SIRT1 by L-serine increases fatty acid oxidation and reverses insulin resistance in C2C12 myotubes. | 2019 | Details |
| A47154 | 24797033 | Alcohol Clin Exp Res | Involvement of insulin resistance in the protective effect of metformin against alcoholic liver injury. | 2014 | Details |
| A47204 | 22988930 | J Gastroenterol Hepatol | Chronic alcohol-induced hepatic insulin resistance and endoplasmic reticulum stress ameliorated by peroxisome-proliferator activated receptor-δ agonist treatment. | 2013 | Details |
| A47227 | 22234172 | Am J Pathol | Chronic alcohol exposure stimulates adipose tissue lipolysis in mice: role of reverse triglyceride transport in the pathogenesis of alcoholic steatosis. | 2012 | Details |
| A47239 | 21790669 | Alcohol Clin Exp Res | Limited therapeutic effect of N-acetylcysteine on hepatic insulin resistance in an experimental model of alcohol-induced steatohepatitis. | 2011 | Details |
| A47292 | 18722787 | Cytokine | Fat diet and alcohol-induced steatohepatitis after LPS challenge in mice: role of bioactive TNF and Th1 type cytokines. | 2008 | Details |
| A47297 | 18534708 | Diabetes Res Clin Pract | Fatty liver and chronic inflammation in Chinese adults. | 2008 | Details |
| A47336 | 16170395 | Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub | High adiponectin and TNF-alpha levels in moderate drinkers suffering from liver steatosis: comparison with non drinkers suffering from similar hepatopathy. | 2005 | Details |
| A47337 | 16115302 | J Intern Med | Circulating adiponectin reflects severity of liver disease but not insulin sensitivity in liver cirrhosis. | 2005 | Details |
| A47609 | 35156314 | Obesity (Silver Spring) | Suppression of RIP1 activity via S415 dephosphorylation ameliorates obesity-related hepatic insulin resistance. | 2022 | Details |
| A47616 | 35053615 | Cancers (Basel) | CD26/DPP4 as a Therapeutic Target in Nonalcoholic Steatohepatitis Associated Hepatocellular Carcinoma. | 2022 | Details |
| A47630 | 34732847 | Lab Invest | Hepatocyte-specific fibroblast growth factor 21 overexpression ameliorates high-fat diet-induced obesity and liver steatosis in mice. | 2021 | Details |
| A47684 | 33738905 | Obes Rev | Neutral sphingomyelinase-2 and cardiometabolic diseases. | 2021 | Details |
| A47728 | 32830851 | J Clin Endocrinol Metab | Identification of Proteins Associated with the Early Restoration of Insulin Sensitivity After Biliopancreatic Diversion. | 2020 | Details |
| A47770 | 32213649 | Endocrinol Diabetes Metab Case Rep | The complicated clinical course in a case of atypical lipodystrophy after development of neutralizing antibody to metreleptin: treatment with setmelanotide. | 2020 | Details |
| A47815 | 31434650 | Diabetes Care | Acquired Generalized Lipodystrophy: A New Cause of Anti-PD-1 Immune-Related Diabetes. | 2019 | Details |
| A47857 | 30759233 | J Clin Endocrinol Metab | Massive Ovarian Growth in a Woman With Severe Insulin-Resistant Polycystic Ovary Syndrome Receiving GnRH Analogue. | 2019 | Details |
| A47873 | 30393432 | J Toxicol Pathol | Hepatic lesions induced by feeding Western diets to Zucker fatty rats, an insulin-resistant model. | 2018 | Details |
| A47900 | 29733507 | Mol Nutr Food Res | High Fat Diets Composed of Palm Stearin and Olive Oil Equally Exacerbate Liver Inflammatory Damage and Metabolic Stress in Mice. | 2018 | Details |
| A47904 | 29607946 | Intern Med | Clinical Characteristics, Phenotype of Lipodystrophy and a Genetic Analysis of Six Diabetic Japanese Women with Familial Partial Lipodystrophy in a Diabetic Outpatient Clinic. | 2018 | Details |
| A48016 | 26486483 | Vnitr Lek | [Polycystic ovary syndrome]. | 2015 | Details |