Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Glutathione718 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A46252 | 20008062 | J Pharmacol Exp Ther | A silybin-phospholipid complex prevents mitochondrial dysfunction in a rodent model of nonalcoholic steatohepatitis. | 2009 | Details |
| A46309 | 19602140 | Liver Int | Teucrium polium in prevention of steatohepatitis in rats. | 2009 | Details |
| A46338 | 19453104 | J Agric Food Chem | Flaxseed oil attenuates nonalcoholic fatty liver of hyperlipidemic hamsters. | 2009 | Details |
| A46695 | 16470305 | Braz J Med Biol Res | Liver mitochondrial dysfunction and oxidative stress in the pathogenesis of experimental nonalcoholic fatty liver disease. | 2006 | Details |
| A46729 | 16161764 | J Nutr Sci Vitaminol (Tokyo) | Influence of royal jelly on mouse hepatic gene expression and safety assessment with a DNA microarray. | 2005 | Details |
| A46779 | 15632182 | J Biol Chem | Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling. | 2005 | Details |
| A46967 | 32045450 | PLoS One | Mesenchymal stem cells reduce alcoholic hepatitis in mice via suppression of hepatic neutrophil and macrophage infiltration, and of oxidative stress. | 2020 | Details |
| A46982 | 31336037 | Mol Nutr Food Res | The Preventative Effects of Procyanidin on Binge Ethanol-Induced Lipid Accumulation and ROS Overproduction via the Promotion of Hepatic Autophagy. | 2019 | Details |
| A47038 | 28500689 | IUBMB Life | Blockade of hedgehog pathway is required for the protective effects of magnesium isoglycyrrhizinate against ethanol-induced hepatocyte steatosis and apoptosis. | 2017 | Details |
| A47053 | 27821289 | J Nutr Biochem | Evaluating the effects of refined carbohydrate and fat diets with acute ethanol consumption using a mouse model of alcoholic liver injury. | 2016 | Details |
| A47059 | 27455313 | Nutrients | Barley Sprouts Extract Attenuates Alcoholic Fatty Liver Injury in Mice by Reducing Inflammatory Response. | 2016 | Details |
| A47075 | 26801973 | BMC Complement Altern Med | Hepatoprotective effect of licorice, the root of Glycyrrhiza uralensis Fischer, in alcohol-induced fatty liver disease. | 2016 | Details |
| A47078 | 26626356 | J Microbiol | Lactobacillus rhamnosus CCFM1107 treatment ameliorates alcohol-induced liver injury in a mouse model of chronic alcohol feeding. | 2015 | Details |
| A47080 | 26610588 | Biomolecules | High Intrinsic Aerobic Capacity Protects against Ethanol-Induced Hepatic Injury and Metabolic Dysfunction: Study Using High Capacity Runner Rat Model. | 2015 | Details |
| A47088 | 26459052 | Int Immunopharmacol | Ligustrazine prevents alcohol-induced liver injury by attenuating hepatic steatosis and oxidative stress. | 2015 | Details |
| A47096 | 26030870 | PLoS One | Establishment of the tree shrew as an alcohol-induced Fatty liver model for the study of alcoholic liver diseases. | 2015 | Details |
| A47117 | 25644346 | J Nutr | L-serine supplementation attenuates alcoholic fatty liver by enhancing homocysteine metabolism in mice and rats. | 2014 | Details |
| A47126 | 25494594 | Lipids Health Dis | Protective effect of corn peptides against alcoholic liver injury in men with chronic alcohol consumption: a randomized double-blind placebo-controlled study. | 2014 | Details |
| A47129 | 25455889 | Food Chem Toxicol | Berberine protects liver from ethanol-induced oxidative stress and steatosis in mice. | 2014 | Details |
| A47143 | 25024695 | Front Pharmacol | Glutathione and mitochondria. | 2014 | Details |
| A47146 | 24930470 | Alcohol Clin Exp Res | Pyrroloquinoline quinone-secreting probiotic Escherichia coli Nissle 1917 ameliorates ethanol-induced oxidative damage and hyperlipidemia in rats. | 2014 | Details |
| A47152 | 24815155 | Transplant Proc | Γ-glutamyl transferase as an early and sensitive marker in ethanol-induced liver injury of rats. | 2014 | Details |
| A47177 | 24146112 | Arch Toxicol | Protective effects of dioscin against alcohol-induced liver injury. | 2013 | Details |
| A47184 | 23922897 | PLoS One | Acetaldehyde-derived advanced glycation end-products promote alcoholic liver disease. | 2013 | Details |
| A47185 | 23907024 | Food Chem Toxicol | A role for lipid rafts in the protection afforded by docosahexaenoic acid against ethanol toxicity in primary rat hepatocytes. | 2013 | Details |
| A47196 | 23337955 | Int J Mol Med | Analysis of differentially expressed genes and microRNAs in alcoholic liver disease. | 2013 | Details |
| A47206 | 22905112 | PLoS One | Reduced susceptibility of DNA methyltransferase 1 hypomorphic (Dnmt1N/+) mice to hepatic steatosis upon feeding liquid alcohol diet. | 2012 | Details |
| A47214 | 22564350 | Redox Rep | Ascorbic acid supplementation causes faster restoration of reduced glutathione content in the regression of alcohol-induced hepatotoxicity in male guinea pigs. | 2012 | Details |
| A47217 | 22504843 | Food Chem Toxicol | Hepatoprotective effects of dieckol-rich phlorotannins from Ecklonia cava, a brown seaweed, against ethanol induced liver damage in BALB/c mice. | 2012 | Details |
| A47243 | 21663494 | J Med Food | Hepatoprotective effect of aged black garlic on chronic alcohol-induced liver injury in rats. | 2011 | Details |
| A47250 | 21414374 | Food Chem Toxicol | Herbal formula CGX ameliorates LPS/D-galactosamine-induced hepatitis. | 2011 | Details |
| A47255 | 21105651 | J Agric Food Chem | Gentiana manshurica Kitagawa reverses acute alcohol-induced liver steatosis through blocking sterol regulatory element-binding protein-1 maturation. | 2010 | Details |
| A47262 | 20192205 | J Agric Food Chem | Fruiting body of Niuchangchih (Antrodia camphorata) protects livers against chronic alcohol consumption damage. | 2010 | Details |
| A47278 | 19372631 | J Pharmacol Sci | Magnolia officinalis reverses alcoholic fatty liver by inhibiting the maturation of sterol regulatory element-binding protein-1c. | 2009 | Details |
| A47279 | 19371623 | Toxicol Appl Pharmacol | Honokiol reverses alcoholic fatty liver by inhibiting the maturation of sterol regulatory element binding protein-1c and the expression of its downstream lipogenesis genes. | 2009 | Details |
| A47281 | 19239162 | Adv Exp Med Biol | Effect of taurine on alcoholic liver disease in rats. | 2009 | Details |
| A47290 | 19003881 | Hepatology | Ethanol and arachidonic acid synergize to activate Kupffer cells and modulate the fibrogenic response via tumor necrosis factor alpha, reduced glutathione, and transforming growth factor beta-dependent mechanisms. | 2008 | Details |
| A47298 | 18509591 | Amino Acids | Effect of taurine on alcoholic liver disease in rats. | 2008 | Details |
| A47301 | 18336673 | J Gastroenterol Hepatol | Cholesterol and sphingolipids in alcohol-induced liver injury. | 2008 | Details |
| A47305 | 18339590 | Dig Liver Dis | Inhibitory effect of osthole on alcohol-induced fatty liver in mice. | 2008 | Details |
| A47312 | 17616758 | Am J Clin Nutr | Role of S-adenosylmethionine, folate, and betaine in the treatment of alcoholic liver disease: summary of a symposium. | 2007 | Details |
| A47315 | 17361525 | Chin J Integr Med | Intervention effects of Jianpi Liqi Huoxue Decoction on lipid peroxidative liver injury induced by alcohol. | 2006 | Details |
| A47326 | 16958678 | J Gastroenterol Hepatol | Unfolding new mechanisms of alcoholic liver disease in the endoplasmic reticulum. | 2006 | Details |
| A47331 | 16462037 | Biol Pharm Bull | Glycoprotein isolated from Acanthopanax senticosus protects against hepatotoxicity induced by acute and chronic alcohol treatment. | 2006 | Details |
| A47347 | 15215328 | Mutagenesis | Polymorphisms in glutathione S-transferases GSTM1, GSTT1 and GSTP1 and cytochromes P450 CYP2E1 and CYP1A1 and susceptibility to cirrhosis or pancreatitis in alcoholics. | 2004 | Details |
| A47358 | 12711653 | Alcohol Alcohol | Polyenylphosphatidylcholine corrects the alcohol-induced hepatic oxidative stress by restoring s-adenosylmethionine. | 2003 | Details |
| A47359 | 12635862 | Int J Tissue React | Long-term ethanol administration enhances age-dependent modulation of redox state in different brain regions in the rat: protection by acetyl carnitine. | 2002 | Details |
| A47371 | 11320206 | Proc Natl Acad Sci U S A | Methionine adenosyltransferase 1A knockout mice are predisposed to liver injury and exhibit increased expression of genes involved in proliferation. | 2001 | Details |
| A47380 | 10397283 | Alcohol Clin Exp Res | Microsomal ethanol-oxidizing system (MEOS): the first 30 years (1968-1998)--a review. | 1999 | Details |
| A47405 | 9113278 | Alcohol Clin Exp Res | Polyenylphosphatidylcholine decreases alcohol-induced oxidative stress in the baboon. | 1997 | Details |
| A47425 | 7569285 | Recenti Prog Med | [Glutathione in the treatment of chronic fatty liver diseases]. | 1995 | Details |
| A47526 | 3518564 | Ann Intern Med | Drug-induced hepatotoxicity. | 1986 | Details |
| A47584 | 6861588 | Dig Dis Sci | Depressed hepatic glutathione and increased diene conjugates in alcoholic liver disease. Evidence of lipid peroxidation. | 1983 | Details |
| A47741 | 32647111 | Cell Death Dis | The emerging role of ferroptosis in non-cancer liver diseases: hype or increasing hope? | 2020 | Details |
| A48070 | 25092871 | Mol Cell Biol | Transcription factor Nrf1 negatively regulates the cystine/glutamate transporter and lipid-metabolizing enzymes. | 2014 | Details |
| A48413 | 12060674 | FASEB J | Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A. | 2002 | Details |
| A48515 | 35024626 | STAR Protoc | GST-Perfringolysin O production for the localization and quantification of membrane cholesterol in human and mouse brain and liver. | 2021 | Details |
| A48614 | 32987701 | Antioxidants (Basel) | Mitochondrial Glutathione: Recent Insights and Role in Disease. | 2020 | Details |
| A48698 | 31234428 | Medicina (Kaunas) | Alterations of Methionine Metabolism as Potential Targets for the Prevention and Therapy of Hepatocellular Carcinoma. | 2019 | Details |
| A48848 | 26701066 | Toxicol Appl Pharmacol | Genetically obese (ob/ob) mice are resistant to the lethal effects of thioacetamide hepatotoxicity. | 2015 | Details |
| A48908 | 24814604 | Am J Pathol | Adverse signaling of scavenger receptor class B1 and PGC1s in alcoholic hepatosteatosis and steatohepatitis and protection by betaine in rat. | 2014 | Details |
| A48975 | 22543705 | Acta Pharmacol Sin | Protective effects of tiopronin against high fat diet-induced non-alcoholic steatohepatitis in rats. | 2012 | Details |
| A48978 | 22452372 | Br J Pharmacol | Curcumin ameliorates hepatic fibrosis in type 2 diabetes mellitus - insights into its mechanisms of action. | 2012 | Details |
| A48983 | 22352842 | Br J Pharmacol | Curcumin inhibits gene expression of receptor for advanced glycation end-products (RAGE) in hepatic stellate cells in vitro by elevating PPARγ activity and attenuating oxidative stress. | 2012 | Details |
| A49017 | 21195127 | Mol Cell Endocrinol | Curcumin diminishes the impacts of hyperglycemia on the activation of hepatic stellate cells by suppressing membrane translocation and gene expression of glucose transporter-2. | 2010 | Details |
| A49099 | 17845508 | Basic Clin Pharmacol Toxicol | Silymarin prevents palmitate-induced lipotoxicity in HepG2 cells: involvement of maintenance of Akt kinase activation. | 2007 | Details |
| A49154 | 16137475 | Gastroenterol Hepatol | [Etiopathogenesis of non-alcoholic steatohepatitis]. | 2005 | Details |
| A49157 | 16054984 | Alcohol | Role of methionine adenosyltransferase and S-adenosylmethionine in alcohol-associated liver cancer. | 2005 | Details |
| A49274 | 35804799 | Foods | Consumption of Grapes Modulates Gene Expression, Reduces Non-Alcoholic Fatty Liver Disease, and Extends Longevity in Female C57BL/6J Mice Provided with a High-Fat Western-Pattern Diet. | 2022 | Details |
| A49309 | 35792732 | Biomarkers | Chemical compositions of Commiphora opobalsamum stem bark to alleviate liver complications in streptozotocin-induced diabetes in rats: Role of oxidative stress and DNA damage. | 2022 | Details |
| A49352 | 35780841 | Life Sci | Ellagic acid ameliorates high fructose-induced hyperuricemia and non-alcoholic fatty liver in Wistar rats: Focusing on the role of C1q/tumor necrosis factor-related protein-3 and ATP citrate lyase. | 2022 | Details |
| A49452 | 35745238 | Nutrients | Effects of Calorie Restricted Diet on Oxidative/Antioxidative Status Biomarkers and Serum Fibroblast Growth Factor 21 Levels in Nonalcoholic Fatty Liver Disease Patients: A Randomized, Controlled Clinical Trial. | 2022 | Details |
| A49520 | 35728768 | Free Radic Biol Med | Nonalcoholic steatohepatitis and mechanisms by which it is ameliorated by activation of the CNC-bZIP transcription factor Nrf2. | 2022 | Details |
| A49526 | 35726536 | Eur J Histochem | Ferroptosis resistance cooperates with cellular senescence in the overt stage of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. | 2022 | Details |
| A49747 | 35651050 | Food Res Int | Que Zui tea ameliorates hepatic lipid accumulation and oxidative stress in high fat diet induced nonalcoholic fatty liver disease. | 2022 | Details |
| A49838 | 35624769 | Antioxidants (Basel) | Ramulus Mori (Sangzhi) Alkaloids Alleviate High-Fat Diet-Induced Obesity and Nonalcoholic Fatty Liver Disease in Mice. | 2022 | Details |
| A49922 | 35594708 | Biomed Pharmacother | Exogenous administration of unacylated ghrelin attenuates hepatic steatosis in high-fat diet-fed rats by modulating glucose homeostasis, lipogenesis, oxidative stress, and endoplasmic reticulum stress. | 2022 | Details |
| A50090 | 35531696 | Zhongguo Zhong Yao Za Zhi | [Di'ao Xinxuekang alleviates non-alcoholic steatohepatitis in mice by up-regulating Nrf2/HO-1 signaling pathway]. | 2022 | Details |
| A50124 | 35511653 | Minerva Gastroenterol (Torino) | Treatment with phosphatidylcholine of patients with non-alcoholic fatty liver disease: a prospective pilot study. | 2022 | Details |
| A50188 | 35485140 | Bioengineered | Livogrit Prevents Methionine-Cystine Deficiency Induced Nonalcoholic Steatohepatitis by Modulation of Steatosis and Oxidative Stress in Human Hepatocyte-Derived Spheroid and in Primary Rat Hepatocytes. | 2022 | Details |
| A50320 | 35434600 | Food Chem X | Kombucha - An ancient fermented beverage with desired bioactivities: A narrowed review. | 2022 | Details |
| A50446 | 35388144 | Commun Biol | Glutathione S-transferase Mu 2 inhibits hepatic steatosis via ASK1 suppression. | 2022 | Details |
| A50566 | 35338494 | J Food Biochem | Zingerone ameliorates non-alcoholic fatty liver disease in rats by activating AMPK. | 2022 | Details |
| A50594 | 35330105 | Life (Basel) | Taurine Ameliorates Tunicamycin-Induced Liver Injury by Disrupting the Vicious Cycle between Oxidative Stress and Endoplasmic Reticulum Stress. | 2022 | Details |
| A50760 | 35276900 | Nutrients | Baicalin Attenuates Oxidative Stress in a Tissue-Engineered Liver Model of NAFLD by Scavenging Reactive Oxygen Species. | 2022 | Details |
| A51144 | 35502211 | Oxid Med Cell Longev | Research Progress of Ferroptosis in Adiposity-Based Chronic Disease (ABCD). | 2022 | Details |
| A51146 | 35477568 | Cell Death Discov | Bone morphogenetic protein 4 alleviates nonalcoholic steatohepatitis by inhibiting hepatic ferroptosis. | 2022 | Details |
| A51171 | 35364359 | Nutr Res | Lower plasma glutathione, choline, and betaine concentrations are associated with fatty liver in postmenopausal women. | 2022 | Details |
| A51343 | 35467032 | J Cell Biochem | Physical exercise positively modulates nonalcoholic steatohepatitis-related hepatic endoplasmic reticulum stress. | 2022 | Details |
| A51348 | 35419738 | Inflammation | Melatonin Attenuates Inflammation, Oxidative Stress, and DNA Damage in Mice with Nonalcoholic Steatohepatitis Induced by a Methionine- and Choline-Deficient Diet. | 2022 | Details |
| A51477 | 30627433 | J Nutr Sci | Hot water extract of turmeric (Curcuma longa) prevents non-alcoholic steatohepatitis in mice by inhibiting hepatic oxidative stress and inflammation. | 2018 | Details |
| A51548 | 35290904 | Redox Biol | Mitochondrial depletion of glutaredoxin 2 induces metabolic dysfunction-associated fatty liver disease in mice. | 2022 | Details |
| A51698 | 34820906 | J Vet Intern Med | Treatment and outcomes of dogs with hepatocutaneous syndrome or hepatocutaneous-associated hepatopathy. | 2021 | Details |
| A51766 | 34274572 | Poult Sci | Untargeted and targeted metabolomics profiling reveals the underlying pathogenesis and abnormal arachidonic acid metabolism in laying hens with fatty liver hemorrhagic syndrome. | 2021 | Details |
| A51851 | 33680863 | Toxicol Rep | Alcohol-associated liver disease: A review on its pathophysiology, diagnosis and drug therapy. | 2021 | Details |
| A51856 | 33649799 | Mol Med Rep | Bioinformatics analysis of differentially expressed proteins in alcoholic fatty liver disease treated with recombinant human cytoglobin. | 2021 | Details |
| A51928 | 33168096 | Hum Genomics | Aldh1l2 knockout mouse metabolomics links the loss of the mitochondrial folate enzyme to deregulation of a lipid metabolism observed in rare human disorder. | 2020 | Details |
| A51966 | 32825248 | Nutrients | Biomarkers of Broccoli Consumption: Implications for Glutathione Metabolism and Liver Health. | 2020 | Details |
| A52001 | 32478901 | J Food Biochem | Hypolipidemic and antioxidant activities of Trichosanthes kirilowii maxim seed oil and flavonoids in mice fed with a high-fat diet. | 2020 | Details |
| A52191 | 30282988 | Sci Rep | Maternal high-fat diet consumption induces sex-dependent alterations of the endocannabinoid system and redox homeostasis in liver of adult rat offspring. | 2018 | Details |