Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A03333 | 34040411 | J Inflamm Res | Ginkgo biloba Extract 50 (GBE50) Ameliorates Insulin Resistance, Hepatic Steatosis and Liver Injury in High Fat Diet-Fed Mice. | 2021 | Details |
| A03341 | 34034750 | Lipids Health Dis | Circulating angiopoietin-like proteins in metabolic-associated fatty liver disease: a systematic review and meta-analysis. | 2021 | Details |
| A03348 | 34032730 | Medicine (Baltimore) | Acupuncture for type 2 diabetes mellitus with nonalcoholic fatty liver disease: A protocol for systematic review and meta-analysis. | 2021 | Details |
| A03357 | 34029949 | Biomed Pharmacother | The sodium-glucose cotransporter-2 inhibitor Tofogliflozin prevents the progression of nonalcoholic steatohepatitis-associated liver tumors in a novel murine model. | 2021 | Details |
| A03371 | 34027116 | Clin Exp Hepatol | Comparative study of the effects of Abexol and atorvastatin in patients with non-alcoholic fatty liver disease. | 2021 | Details |
| A03372 | 34027109 | Clin Exp Hepatol | Non-alcoholic fatty liver disease and lipotoxicity. | 2021 | Details |
| A03377 | 34025131 | J Ginseng Res | Effect of Korean Red Ginseng on metabolic syndrome. | 2020 | Details |
| A03383 | 34022879 | BMC Endocr Disord | The application value of serum 25(OH)D3, uric acid, triglyceride, and homeostasis model assessment of insulin resistance in male patients with hyperuricemia combined with hypogonadism. | 2021 | Details |
| A03385 | 34022222 | J Biol Chem | Novel insulin sensitizer MSDC-0602K improves insulinemia and fatty liver disease in mice, alone and in combination with liraglutide. | 2021 | Details |
| A03396 | 34017059 | Exp Mol Med | The interaction between the gut microbiota and dietary carbohydrates in nonalcoholic fatty liver disease. | 2021 | Details |
| A03400 | 34015596 | Int Immunopharmacol | Interleukin-1 in obesity-related low-grade inflammation: From molecular mechanisms to therapeutic strategies. | 2021 | Details |
| A03404 | 34014280 | Dis Model Mech | Synergic effect of atorvastatin and ambrisentan on sinusoidal and hemodynamic alterations in a rat model of NASH. | 2021 | Details |
| A03420 | 34006994 | Eur J Clin Nutr | Non-alcoholic fatty liver disease in obese children and adolescents: a role for nutrition? | 2021 | Details |
| A03424 | 34004342 | J Nutr Biochem | Saskatoon berry powder reduces hepatic steatosis and insulin resistance in high fat-high sucrose diet-induced obese mice. | 2021 | Details |
| A03426 | 34004161 | Gastroenterology | Associations Among Adipose Tissue Immunology, Inflammation, Exosomes and Insulin Sensitivity in People With Obesity and Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03427 | 34003729 | Am J Respir Cell Mol Biol | Hepatocyte HIF-1 and Intermittent Hypoxia Independently Impact Liver Fibrosis in Murine Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03430 | 34002452 | Obes Rev | Bariatric surgery and the liver-Mechanisms, benefits, and risks. | 2021 | Details |
| A03431 | 34002333 | Diabetes Ther | Effects of Liraglutide on Nonalcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. | 2021 | Details |
| A03447 | 33995543 | Evid Based Complement Alternat Med | Network Pharmacology-Based Investigation of the Therapeutic Mechanisms of Action of Danning Tablets in Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03451 | 33995271 | Front Endocrinol (Lausanne) | Pioglitazone for NAFLD Patients With Prediabetes or Type 2 Diabetes Mellitus: A Meta-Analysis. | 2021 | Details |
| A03452 | 33994867 | Int J Biol Sci | MicroRNAs in the Pathogenesis of Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03453 | 33994854 | Int J Biol Sci | Berberine alleviates lipid metabolism disorders via inhibition of mitochondrial complex I in gut and liver. | 2021 | Details |
| A03455 | 33994437 | Intern Med | Effects of Canagliflozin on Hepatic Steatosis, Visceral Fat and Skeletal Muscle among Patients with Type 2 Diabetes and Non-alcoholic Fatty Liver Disease. | 2021 | Details |
| A03456 | 33994069 | Cytokine | Changes in liver steatosis in HIV-positive women are associated with the BMI, but not with biomarkers. | 2021 | Details |
| A03464 | 33992322 | Food Res Int | Long-term supplementation with phenolic compounds from jaboticaba (Plinia jaboticaba (Vell.) Berg) reduces adiposophaty and improves glucose, lipid, and energy metabolism. | 2021 | Details |
| A03468 | 33991615 | Cell Signal | Secretory Galectin-3 promotes hepatic steatosis via regulation of the PPARγ/CD36 signaling pathway. | 2021 | Details |
| A03471 | 33991450 | Physiol Rep | Antisense oligonucleotide-mediated knockdown of Mpzl3 attenuates the negative metabolic effects of diet-induced obesity in mice. | 2021 | Details |
| A03472 | 33991395 | Chem Biodivers | The Therapeutic Effects and Mechanisms of Salidroside on Cardiovascular and Metabolic Diseases: An Updated Review. | 2021 | Details |
| A03474 | 33990765 | Acta Pharmacol Sin | Blueberry-derived exosomes-like nanoparticles ameliorate nonalcoholic fatty liver disease by attenuating mitochondrial oxidative stress. | 2021 | Details |
| A03476 | 33989817 | Cell Mol Gastroenterol Hepatol | Sodium Butyrate Supplementation Inhibits Hepatic Steatosis by Stimulating Liver Kinase B1 and Insulin-Induced Gene. | 2021 | Details |
| A03478 | 33989548 | Cell | Mechanisms and disease consequences of nonalcoholic fatty liver disease. | 2021 | Details |
| A03480 | 33988719 | J Mol Cell Biol | Knockdown of insulin-like growth factor 2 gene disrupts mitochondrial functions in the liver. | 2021 | Details |
| A03482 | 33987427 | Ann Transl Med | Non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH)-related liver fibrosis: mechanisms, treatment and prevention. | 2021 | Details |
| A03492 | 33984335 | Metabolism | Fenofibrate, a PPARα agonist, reduces hepatic fat accumulation through the upregulation of TFEB-mediated lipophagy. | 2021 | Details |
| A03509 | 33977096 | Can J Gastroenterol Hepatol | NAFLD and Infection, a Nuanced Relationship. | 2021 | Details |
| A03511 | 33975804 | Trends Endocrinol Metab | Links between metabolic syndrome and metabolic dysfunction-associated fatty liver disease. | 2021 | Details |
| A03513 | 33974978 | Free Radic Biol Med | Effects of astaxanthin in animal models of obesity-associated diseases: A systematic review and meta-analysis. | 2021 | Details |
| A03515 | 33974725 | Phytother Res | Effects of garlic powder supplementation on metabolic syndrome components, insulin resistance, fatty liver index, and appetite in subjects with metabolic syndrome: A randomized clinical trial. | 2021 | Details |
| A03520 | 33972568 | Sci Rep | Allopurinol ameliorates high fructose diet induced hepatic steatosis in diabetic rats through modulation of lipid metabolism, inflammation, and ER stress pathway. | 2021 | Details |
| A03522 | 33971815 | BMC Gastroenterol | Normalization of γ-glutamyl transferase levels is associated with better metabolic control in individuals with nonalcoholic fatty liver disease. | 2021 | Details |
| A03526 | 33969054 | World J Clin Cases | Polycystic ovary syndrome: Pathways and mechanisms for possible increased susceptibility to COVID-19. | 2021 | Details |
| A03527 | 33967948 | Front Endocrinol (Lausanne) | Non-Alcoholic Fatty Liver Disease and Hypokalemia in Primary Aldosteronism Among Chinese Population. | 2021 | Details |
| A03531 | 33966916 | Arch Med Res | Hepatic Accumulation of Hypoxanthine: A Link Between Hyperuricemia and Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03535 | 33965533 | J Nutr Biochem | Toll-like receptor 3 ablation prevented high-fat diet-induced obesity and metabolic disorder. | 2021 | Details |
| A03542 | 33962276 | Ecotoxicol Environ Saf | Copper exposure association with prevalence of non-alcoholic fatty liver disease and insulin resistance among US adults (NHANES 2011-2014). | 2021 | Details |
| A03552 | 33960110 | Obes Rev | Effect of exercise on cardiometabolic health of adults with overweight or obesity: Focus on blood pressure, insulin resistance, and intrahepatic fat-A systematic review and meta-analysis. | 2021 | Details |
| A03554 | 33957975 | BMC Res Notes | Association of 45-bp ins/del polymorphism of uncoupling protein 2 (UCP2) and susceptibility to nonalcoholic fatty liver and type 2 diabetes mellitus in North-west of Iran. | 2021 | Details |
| A03564 | 33952843 | Nihon Yakurigaku Zasshi | [The roles of gap junctional intercellular communication in non-alcoholic steatohepatitis (NASH) and liver fibrosis]. | 2021 | Details |
| A03566 | 33952255 | Lipids Health Dis | Screening for the presence of scleroedema adultorum of Buschke in patients with diabetes mellitus: newly diagnosed patients had a high prevalence of dyslipidaemia. | 2021 | Details |
| A03567 | 33951744 | Andrologia | Predicting risk of erectile dysfunction in patients with nonalcoholic fatty liver disease. | 2021 | Details |
| A03572 | 33948987 | FASEB J | Porphyran-derived oligosaccharides alleviate NAFLD and related cecal microbiota dysbiosis in mice. | 2021 | Details |
| A03574 | 33948068 | Ann Gastroenterol | Effectiveness of dietary interventions on cardio-metabolic risk factors in patients with nonalcoholic fatty liver disease: a systematic review and meta-analysis of randomized controlled trials. | 2021 | Details |
| A03579 | 33946843 | Microorganisms | Gut Microbiota and NAFLD: Pathogenetic Mechanisms, Microbiota Signatures, and Therapeutic Interventions. | 2021 | Details |
| A03583 | 33943028 | J Diabetes Investig | Liver fibrosis is independently associated with diabetic peripheral neuropathy in type 2 diabetes mellitus. | 2021 | Details |
| A03584 | 33942524 | Pediatr Obes | Association between ectopic pancreatic and hepatic fat and metabolic risk factors in children with non-alcoholic fatty liver disease. | 2021 | Details |
| A03585 | 33941551 | BMJ Open Diabetes Res Care | Insulin resistance and liver histopathology in metabolically unhealthy subjects do not correlate with the hepatic abundance of NLRP3 inflammasome nor circulating IL-1β levels. | 2021 | Details |
| A03590 | 33939383 | Clin Transl Gastroenterol | Moderate-Intensity Aerobic vs Resistance Exercise and Dietary Modification in Patients With Nonalcoholic Fatty Liver Disease: A Randomized Clinical Trial. | 2021 | Details |
| A03600 | 33937257 | Front Cell Dev Biol | Autophagy in Hepatic Steatosis: A Structured Review. | 2021 | Details |
| A03602 | 33935810 | Front Physiol | Serum Creatinine-to-Cystatin C Ratio in the Progression Monitoring of Non-alcoholic Fatty Liver Disease. | 2021 | Details |
| A03604 | 33935282 | Int J Obes (Lond) | The effect of physical activity level and exercise training on the association between plasma branched-chain amino acids and intrahepatic lipid content in participants with obesity. | 2021 | Details |
| A03606 | 33933462 | Exp Neurol | Liver inflammation at the time of spinal cord injury enhances intraspinal pathology, liver injury, metabolic syndrome and locomotor deficits. | 2021 | Details |
| A03622 | 33926132 | Metabolites | Dietary Macronutrient Composition Differentially Modulates the Remodeling of Mitochondrial Oxidative Metabolism during NAFLD. | 2021 | Details |
| A03629 | 33924909 | Diagnostics (Basel) | Liver Fibrosis and Steatosis in Alström Syndrome: A Genetic Model for Metabolic Syndrome. | 2021 | Details |
| A03630 | 33924725 | Nutrients | The Combination of Berberine, Tocotrienols and Coffee Extracts Improves Metabolic Profile and Liver Steatosis by the Modulation of Gut Microbiota and Hepatic miR-122 and miR-34a Expression in Mice. | 2021 | Details |
| A03633 | 33923817 | Int J Mol Sci | Role of Insulin Resistance in MAFLD. | 2021 | Details |
| A03635 | 33923525 | Nutrients | The Role of Fructose in Non-Alcoholic Steatohepatitis: Old Relationship and New Insights. | 2021 | Details |
| A03637 | 33923295 | Int J Mol Sci | Mitochondrial Mutations and Genetic Factors Determining NAFLD Risk. | 2021 | Details |
| A03639 | 33923175 | Cells | Adipocyte, Immune Cells, and miRNA Crosstalk: A Novel Regulator of Metabolic Dysfunction and Obesity. | 2021 | Details |
| A03645 | 33921370 | Int J Environ Res Public Health | Xylo-Oligosaccharides in Prevention of Hepatic Steatosis and Adipose Tissue Inflammation: Associating Taxonomic and Metabolomic Patterns in Fecal Microbiomes with Biclustering. | 2021 | Details |
| A03649 | 33920751 | Metabolites | Presence and Implications of Sarcopenia in Non-alcoholic Steatohepatitis. | 2021 | Details |
| A03651 | 33919415 | Antioxidants (Basel) | Lyophilized Maqui (Aristotelia chilensis) Berry Administration Suppresses High-Fat Diet-Induced Liver Lipogenesis through the Induction of the Nuclear Corepressor SMILE. | 2021 | Details |
| A03652 | 33919190 | Antioxidants (Basel) | The Impact of H2S on Obesity-Associated Metabolic Disturbances. | 2021 | Details |
| A03665 | 33915261 | J Nutr Biochem | Consumption of soybean or olive oil at recommended concentrations increased the intestinal microbiota diversity and insulin sensitivity and prevented fatty liver compared to the effects of coconut oil. | 2021 | Details |
| A03670 | 33912410 | Tzu Chi Med J | Role of diet and lifestyle modification in the management of nonalcoholic fatty liver disease and type 2 diabetes. | 2020 | Details |
| A03672 | 33912032 | Front Pharmacol | 5-Bis-(2,6-difluoro-benzylidene) Cyclopentanone Acts as a Selective 11β-Hydroxysteroid Dehydrogenase one Inhibitor to Treat Diet-Induced Nonalcoholic Fatty Liver Disease in Mice. | 2021 | Details |
| A03674 | 33909947 | Mol Nutr Food Res | Effects of Insoluble Cereal Fibre on Body Fat Distribution in the Optimal Fibre Trial. | 2021 | Details |
| A03677 | 33907839 | Int J Mol Med | Role of 2‑series prostaglandins in the pathogenesis of type 2 diabetes mellitus and non‑alcoholic fatty liver disease (Review). | 2021 | Details |
| A03682 | 33903707 | Sci Rep | MicroRNA Let-7 targets AMPK and impairs hepatic lipid metabolism in offspring of maternal obese pregnancies. | 2021 | Details |
| A03684 | 33902605 | Lipids Health Dis | Elucidation of SIRT-1/PGC-1α-associated mitochondrial dysfunction and autophagy in nonalcoholic fatty liver disease. | 2021 | Details |
| A03688 | 33901779 | Ecotoxicol Environ Saf | Dysregulation of autophagy acts as a pathogenic mechanism of non-alcoholic fatty liver disease (NAFLD) induced by common environmental pollutants. | 2021 | Details |
| A03694 | 33900338 | Food Funct | Myricetin improves metabolic outcomes but not cognitive deficit associated to metabolic syndrome in male mice. | 2021 | Details |
| A03700 | 33898960 | JHEP Rep | Treatment of NAFLD with intermittent calorie restriction or low-carb high-fat diet - a randomised controlled trial. | 2021 | Details |
| A03702 | 33898958 | JHEP Rep | Weight-loss-independent benefits of exercise on liver steatosis and stiffness in Japanese men with NAFLD. | 2021 | Details |
| A03703 | 33897617 | Front Endocrinol (Lausanne) | Mining Gut Microbiota From Bariatric Surgery for MAFLD. | 2021 | Details |
| A03704 | 33897616 | Front Endocrinol (Lausanne) | Glucagon-Like Peptide-1 Receptor Agonists for Non-Alcoholic Fatty Liver Disease in Type 2 Diabetes: A Meta-Analysis. | 2021 | Details |
| A03710 | 33895552 | Biochem Biophys Res Commun | The PDE5 inhibitor udenafil ameliorates nonalcoholic fatty liver disease by improving mitochondrial function. | 2021 | Details |
| A03715 | 33894178 | Am J Pathol | Inhibition of Estrogen-Related Receptor α Blocks Liver Steatosis and Steatohepatitis and Attenuates Triglyceride Biosynthesis. | 2021 | Details |
| A03720 | 33893355 | Sci Rep | Liver fat scores do not reflect interventional changes in liver fat content induced by high-protein diets. | 2021 | Details |
| A03722 | 33892169 | Mol Metab | Metabolic-associated fatty liver disease and lipoprotein metabolism. | 2021 | Details |
| A03727 | 33889132 | Front Endocrinol (Lausanne) | Non-Alcoholic Fatty Liver Disease in Obese Youth With Insulin Resistance and Type 2 Diabetes. | 2021 | Details |
| A03729 | 33887577 | Int Immunopharmacol | Neutrophil: An emerging player in the occurrence and progression of metabolic associated fatty liver disease. | 2021 | Details |
| A03733 | 33885048 | Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub | Effect of bariatric surgery on fatty liver disease in obese patients: A prospective one year follow-up study. | 2021 | Details |
| A03734 | 33883996 | Int J Endocrinol | Circulating Prokineticin 2 Levels Are Increased in Children with Obesity and Correlated with Insulin Resistance. | 2021 | Details |
| A03736 | 33883616 | Sci Rep | Non-alcoholic fatty liver disease is associated with bacterial translocation and a higher inflammation response in psoriatic patients. | 2021 | Details |
| A03737 | 33883445 | Curr Opin Lipidol | Nonalcohol fatty liver disease: balancing supply and utilization of triglycerides. | 2021 | Details |
| A03738 | 33883285 | Endocr Connect | Activation of heat shock response improves biomarkers of NAFLD in patients with metabolic diseases. | 2021 | Details |
| A03740 | 33882758 | Expert Rev Clin Pharmacol | Effects of anti-diabetic treatments in type 2 diabetes and fatty liver disease. | 2021 | Details |
| A03743 | 33880813 | Phytother Res | Effect of Portulaca Oleracea (purslane) extract on liver enzymes, lipid profile, and glycemic status in nonalcoholic fatty liver disease: A randomized, double-blind clinical trial. | 2021 | Details |
| A03749 | 33878988 | Expert Rev Gastroenterol Hepatol | Liver-spleen axis in nonalcoholic fatty liver disease. | 2021 | Details |
| A03750 | 33878875 | Arch Iran Med | Hepatic Steatosis and Fibrosis in Type 2 Diabetes: A Risk-Based Approach to Targeted Screening. | 2021 | Details |