Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A26287 | 20728571 | Clin Gastroenterol Hepatol | Regional anthropometric measures and hepatic fibrosis in patients with nonalcoholic Fatty liver disease. | 2010 | Details |
| A26293 | 20708005 | Gastroenterology | Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease. | 2010 | Details |
| A26295 | 20699492 | Indian J Pathol Microbiol | Comparison of clinical, biochemical and histological features of alcoholic steatohepatitis and non-alcoholic steatohepatitis in Asian Indian patients. | 2010 | Details |
| A26300 | 20684021 | Hepatology | The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease. | 2010 | Details |
| A26307 | 20666992 | Liver Int | Diagnosis of different liver fibrosis characteristics by blood tests in non-alcoholic fatty liver disease. | 2010 | Details |
| A26309 | 20664958 | Int J Mol Med | Selective aldosterone blocker ameliorates the progression of non-alcoholic steatohepatitis in rats. | 2010 | Details |
| A26310 | 20664312 | Korean J Gastroenterol | [Nonalcoholic fatty liver disease]. | 2010 | Details |
| A26312 | 20661251 | Int J Obes (Lond) | Visceral adiposity and insulin resistance are independent predictors of the presence of non-cirrhotic NAFLD-related portal hypertension. | 2010 | Details |
| A26316 | 20658156 | J Gastroenterol | Efficacy of long-term ezetimibe therapy in patients with nonalcoholic fatty liver disease. | 2010 | Details |
| A26319 | 20655124 | J Hepatol | Down-regulation of SREBP-1c is associated with the development of burned-out NASH. | 2010 | Details |
| A26325 | 20648476 | Hepatology | Clinical, laboratory and histological associations in adults with nonalcoholic fatty liver disease. | 2010 | Details |
| A26326 | 20648474 | Hepatology | I148M patatin-like phospholipase domain-containing 3 gene variant and severity of pediatric nonalcoholic fatty liver disease. | 2010 | Details |
| A26335 | 20631297 | J Lipid Res | Mass spectrometric profiling of oxidized lipid products in human nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. | 2010 | Details |
| A26341 | 20625773 | J Gastroenterol | Accurate and simple method for quantification of hepatic fat content using magnetic resonance imaging: a prospective study in biopsy-proven nonalcoholic fatty liver disease. | 2010 | Details |
| A26344 | 20624207 | Liver Int | The challenge of developing novel pharmacological therapies for non-alcoholic steatohepatitis. | 2010 | Details |
| A26348 | 20619513 | Clin Nutr | The therapeutic potential of long-chain omega-3 fatty acids in nonalcoholic fatty liver disease. | 2010 | Details |
| A26350 | 20608031 | Lik Sprava | [Efficiency of complex therapy in the treatment of non-alcoholic steatohepatitis and prevention of liver fibrosis]. | 2010 | Details |
| A26353 | 20604719 | Scand J Clin Lab Invest | Circulating levels of interleukin-18 in patients with non-alcoholic fatty liver disease. | 2010 | Details |
| A26363 | 20584330 | BMC Gastroenterol | Validation of the BARD scoring system in Polish patients with nonalcoholic fatty liver disease (NAFLD). | 2010 | Details |
| A26365 | 20582634 | Sleep Breath | An experimental research on chronic intermittent hypoxia leading to liver injury. | 2010 | Details |
| A26366 | 20581244 | Gut | Disease progression of non-alcoholic fatty liver disease: a prospective study with paired liver biopsies at 3 years. | 2010 | Details |
| A26367 | 20580331 | Dig Liver Dis | Relationship between portal chronic inflammation and disease severity in paediatric non-alcoholic fatty liver disease. | 2010 | Details |
| A26368 | 20580037 | Metabolism | Serum levels of vaspin, obestatin, and apelin-36 in patients with nonalcoholic fatty liver disease. | 2010 | Details |
| A26379 | 20561029 | Eur J Clin Invest | Assessment of liver stiffness in subjects affected by familial combined hyperlipidaemia with hepatic steatosis. | 2010 | Details |
| A26380 | 20560816 | Scand J Gastroenterol | A novel non-alcoholic steatohepatitis animal model featured with insulin resistance, hepatic inflammation and fibrosis. | 2010 | Details |
| A26383 | 20556538 | Obes Surg | Nonalcoholic fatty liver disease associated with obstructive sleep apnea: just a coincidence? | 2010 | Details |
| A26388 | 20548286 | Lab Invest | Attenuated progression of diet-induced steatohepatitis in glutathione-deficient mice. | 2010 | Details |
| A26391 | 20532833 | Obes Surg | A biomarker panel for non-alcoholic steatohepatitis (NASH) and NASH-related fibrosis. | 2011 | Details |
| A26394 | 20529989 | Radiology | Nonalcoholic fatty liver disease: US-based acoustic radiation force impulse elastography. | 2010 | Details |
| A26396 | 20526006 | Ann Hepatol | Nonalcoholic fatty liver disease in asymptomatic obese women. | 2010 | Details |
| A26397 | 20526777 | Eur Radiol | Transient elastography with a new probe for obese patients for non-invasive staging of non-alcoholic steatohepatitis. | 2010 | Details |
| A26398 | 20524936 | Clin Sci (Lond) | Significance of serum adiponectin levels in patients with chronic liver disease. | 2010 | Details |
| A26402 | 20512988 | Hepatology | Accumulation of natural killer T cells in progressive nonalcoholic fatty liver disease. | 2010 | Details |
| A26407 | 20506389 | J Cell Biochem | ERp57 is up-regulated in free fatty acids-induced steatotic L-02 cells and human nonalcoholic fatty livers. | 2010 | Details |
| A26408 | 20505526 | J Clin Gastroenterol | Generalizability of the nonalcoholic steatohepatitis Clinical Research Network histologic scoring system for nonalcoholic fatty liver disease. | 2011 | Details |
| A26410 | 20503453 | World J Gastroenterol | Nonalcoholic fatty liver disease and HFE gene mutations: a Polish study. | 2010 | Details |
| A26414 | 20497147 | Aliment Pharmacol Ther | Differential expression of miRNAs in the visceral adipose tissue of patients with non-alcoholic fatty liver disease. | 2010 | Details |
| A26415 | 20496475 | Pediatr Res | Severity of liver injury and atherogenic lipid profile in children with nonalcoholic fatty liver disease. | 2010 | Details |
| A26418 | 20492324 | J Gastroenterol Hepatol | A fresh look at NASH pathogenesis. Part 1: the metabolic movers. | 2010 | Details |
| A26421 | 20487204 | J Pharm Pharmacol | Effects of Eriobotrya japonica seed extract on oxidative stress in rats with non-alcoholic steatohepatitis. | 2010 | Details |
| A26422 | 20485253 | Minerva Gastroenterol Dietol | Weight loss: cornerstone in the treatment of non-alcoholic fatty liver disease. | 2010 | Details |
| A26427 | 20473581 | Obes Surg | Hepatic gene networks in morbidly obese patients with nonalcoholic fatty liver disease. | 2010 | Details |
| A26428 | 20473151 | Curr Opin Clin Nutr Metab Care | Update on nonalcoholic fatty liver disease: genes involved in nonalcoholic fatty liver disease and associated inflammation. | 2010 | Details |
| A26435 | 20460923 | Dig Dis | Surgical treatment of non-alcoholic steatohepatitis and non-alcoholic fatty liver disease. | 2010 | Details |
| A26437 | 20460921 | Dig Dis | Endocannabinoids and their role in fatty liver disease. | 2010 | Details |
| A26438 | 20460920 | Dig Dis | Genetic and environmental susceptibility to non-alcoholic fatty liver disease. | 2010 | Details |
| A26439 | 20460919 | Dig Dis | Animal models of non-alcoholic steatohepatitis: of mice and man. | 2010 | Details |
| A26440 | 20460918 | Dig Dis | PTEN in non-alcoholic fatty liver disease/non-alcoholic steatohepatitis and cancer. | 2010 | Details |
| A26441 | 20460917 | Dig Dis | Molecular mechanisms of hepatic fibrosis in non-alcoholic steatohepatitis. | 2010 | Details |
| A26442 | 20460916 | Dig Dis | Non-alcoholic steatohepatitis pathogenesis: role of repair in regulating the disease progression. | 2010 | Details |
| A26447 | 20460911 | Dig Dis | Pathology and biopsy assessment of non-alcoholic fatty liver disease. | 2010 | Details |
| A26454 | 20459941 | S Afr Med J | Non-alcoholic fatty liver disease (NAFLD) in the Western Cape: a descriptive analysis. | 2010 | Details |
| A26457 | 20458626 | Dig Dis Sci | Digital quantification is more precise than traditional semiquantitation of hepatic steatosis: correlation with fibrosis in 220 treatment-naïve patients with chronic hepatitis C. | 2010 | Details |
| A26463 | 20448542 | Obesity (Silver Spring) | Increased soluble leptin receptor levels in morbidly obese patients with insulin resistance and nonalcoholic fatty liver disease. | 2010 | Details |
| A26465 | 20441224 | J Proteome Res | Phosphoproteomic biomarkers predicting histologic nonalcoholic steatohepatitis and fibrosis. | 2010 | Details |
| A26468 | 20432259 | Hepatology | Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection. | 2010 | Details |
| A26475 | 20421811 | J Clin Gastroenterol | Serum B12 concentration is elevated in patients receiving chronic parenteral nutrition, but is not a marker of intestinal failure-associated liver disease. | 2010 | Details |
| A26478 | 20415685 | Diabetes Obes Metab | The role of adiponectin in the pathogenesis and treatment of non-alcoholic fatty liver disease. | 2010 | Details |
| A26481 | 20412588 | BMC Gastroenterol | Prevalence of liver fibrosis and risk factors in a general population using non-invasive biomarkers (FibroTest). | 2010 | Details |
| A26482 | 20412325 | Hepatol Res | Measurement of spleen volume is useful for distinguishing between simple steatosis and early-stage non-alcoholic steatohepatitis. | 2010 | Details |
| A26483 | 20388946 | J Physiol Pharmacol | Therapy of nonalcoholic fatty liver disease: current status. | 2009 | Details |
| A26485 | 20407430 | Am J Gastroenterol | A role for low hepatic copper concentrations in nonalcoholic Fatty liver disease. | 2010 | Details |
| A26486 | 20406065 | Biomark Med | Is alanine aminotransferase level a surrogate biomarker of hepatic apoptosis in nonalcoholic fatty liver disease? | 2010 | Details |
| A26494 | 20398192 | Pathol Int | Clinicopathological correlations in a series of adult patients with non-alcoholic fatty liver disease. | 2010 | Details |
| A26502 | 20388084 | Curr Pharm Des | Hepatocellular carcinoma and non-alcoholic fatty liver disease: from a clinical to a molecular association. | 2010 | Details |
| A26503 | 20387643 | Ukr Biokhim Zh (1999) | Nonalcoholic fatty liver disease: biochemical and therapeutic considerations. | 2010 | Details |
| A26509 | 20375640 | Korean J Hepatol | [Validity and reliability of the nonalcoholic fatty liver diseases activity score (NAS) in Korean NAFLD patients and its correlation with clinical factors]. | 2010 | Details |
| A26510 | 20373368 | Hepatology | Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease. | 2010 | Details |
| A26512 | 20372110 | Am J Gastroenterol | Association between metabolic syndrome and liver histology among children with nonalcoholic Fatty liver disease. | 2010 | Details |
| A26515 | 20370732 | J Gastroenterol Hepatol | Electron microscopic findings in non-alcoholic fatty liver disease: is there a difference between hepatosteatosis and steatohepatitis? | 2010 | Details |
| A26516 | 20370678 | Curr Pharm Des | Adipocytokines in nonalcoholic fatty liver disease: key players regulating steatosis, inflammation and fibrosis. | 2010 | Details |
| A26517 | 20370677 | Curr Pharm Des | Insulin resistance in nonalcoholic fatty liver disease. | 2010 | Details |
| A26518 | 20370676 | Curr Pharm Des | Leptin: the prototypic adipocytokine and its role in NAFLD. | 2010 | Details |
| A26521 | 20370671 | Curr Pharm Des | Current and future therapeutic strategies in NAFLD. | 2010 | Details |
| A26531 | 20353583 | J Inflamm (Lond) | Elevated endotoxin levels in non-alcoholic fatty liver disease. | 2010 | Details |
| A26532 | 20352596 | Z Gastroenterol | [Histopathological diagnose of non-alcoholic and alcoholic fatty liver disease]. | 2010 | Details |
| A26533 | 20347174 | J Hepatol | Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model. | 2010 | Details |
| A26537 | 20303728 | J Nutr Biochem | Integrated hepatic transcriptome and proteome analysis of mice with high-fat diet-induced nonalcoholic fatty liver disease. | 2010 | Details |
| A26539 | 20301112 | Hepatology | Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease. | 2010 | Details |
| A26540 | 20300479 | Mediators Inflamm | Inflammatory mediators of hepatic steatosis. | 2010 | Details |
| A26544 | 20235368 | Acta Med Croatica | [Ultrasonography in the diagnosis of nonalcoholic fatty liver disease]. | 2009 | Details |
| A26551 | 20221762 | Pathologe | [Histopathological diagnosis of non-alcoholic and alcoholic fatty liver disease. Grade 2 consensus-based guidelines]. | 2010 | Details |
| A26552 | 20221393 | PLoS One | Role of alcohol metabolism in non-alcoholic steatohepatitis. | 2010 | Details |
| A26556 | 20210788 | Basic Clin Pharmacol Toxicol | Hepatic effects of rosiglitazone in rats with the metabolic syndrome. | 2010 | Details |
| A26566 | 20196952 | Zhonghua Gan Zang Bing Za Zhi | [Involvement of endoplasmic reticulum stress in development of fatty liver fibrosis induced by methionine-choline-deficient diet in rats]. | 2010 | Details |
| A26567 | 20196730 | Curr Mol Med | Non-invasive diagnostic tests for non-alcoholic fatty liver disease. | 2010 | Details |
| A26569 | 20195271 | Nat Rev Gastroenterol Hepatol | Pathology of nonalcoholic fatty liver disease. | 2010 | Details |
| A26570 | 20195231 | Panminerva Med | Metabolic syndrome and liver transplantation. | 2009 | Details |
| A26571 | 20189787 | Prostaglandins Leukot Essent Fatty Acids | Fatty liver: role of inflammation and fatty acid nutrition. | 2010 | Details |
| A26572 | 20188144 | Biochim Biophys Acta | Selenium supplementation attenuates procollagen-1 and interleukin-8 production in fat-loaded human C3A hepatoblastoma cells treated with TGFbeta1. | 2010 | Details |
| A26576 | 20181335 | Atherosclerosis | Coronary flow reserve is impaired in patients with nonalcoholic fatty liver disease: association with liver fibrosis. | 2010 | Details |
| A26578 | 20176643 | Gut | Genetic variants regulating insulin receptor signalling are associated with the severity of liver damage in patients with non-alcoholic fatty liver disease. | 2010 | Details |
| A26579 | 20175770 | Aliment Pharmacol Ther | Clinical predictors of fibrosis in patients with chronic liver disease. | 2010 | Details |
| A26580 | 20171943 | Dig Liver Dis | Practice guidelines for the diagnosis and management of nonalcoholic fatty liver disease. A decalogue from the Italian Association for the Study of the Liver (AISF) Expert Committee. | 2010 | Details |
| A26582 | 20168226 | Curr Opin Gastroenterol | Recent advances in nonalcoholic fatty liver disease. | 2010 | Details |
| A26586 | 20158939 | Proc Nutr Soc | Non-alcoholic fatty liver disease: the hepatic consequence of obesity and the metabolic syndrome. | 2010 | Details |
| A26602 | 20112031 | J Gastroenterol | Atorvastatin decreases serum levels of advanced glycation endproducts (AGEs) in nonalcoholic steatohepatitis (NASH) patients with dyslipidemia: clinical usefulness of AGEs as a biomarker for the attenuation of NASH. | 2010 | Details |
| A26607 | 20101745 | Hepatology | Diagnosis of fibrosis and cirrhosis using liver stiffness measurement in nonalcoholic fatty liver disease. | 2010 | Details |
| A26608 | 20101463 | Dig Dis Sci | Nonalcoholic fatty liver disease: a review and update. | 2010 | Details |
| A26609 | 20096896 | Metabolism | Microalbuminuria in nondiabetic patients with nonalcoholic fatty liver disease: association with liver fibrosis. | 2010 | Details |