Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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40433 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A07652 | 32408171 | iScience | High Glucose Induces Lipid Accumulation via 25-Hydroxycholesterol DNA-CpG Methylation. | 2020 | Details |
| A07653 | 32407969 | Clin Gastroenterol Hepatol | Associations Between Nonalcoholic Fatty Liver Disease and Cancers in a Large Cohort in China. | 2020 | Details |
| A07655 | 32407372 | PLoS One | Ablation of Iah1, a candidate gene for diet-induced fatty liver, does not affect liver lipid accumulation in mice. | 2020 | Details |
| A07656 | 32407331 | PLoS One | A pilot study of ex-vivo MRI-PDFF of donor livers for assessment of steatosis and predicting early graft dysfunction. | 2020 | Details |
| A07657 | 32407146 | Arch Physiol Biochem | trans-Chalcone inhibits transforming growth factor-β1 and connective tissue growth factor-dependent collagen expression in the heart of high-fat diet-fed rats. | 2020 | Details |
| A07658 | 32406504 | Biosci Rep | Dysregulation of miR-192-5p in acute pancreatitis patients with nonalcoholic fatty liver and its functional role in acute pancreatitis progression. | 2020 | Details |
| A07659 | 32405967 | J Gastrointest Cancer | Non-hepatic Cancers Independently Predict Liver Decompensation Events. | 2021 | Details |
| A07660 | 32405182 | J Clin Exp Hepatol | Natural History of Simple Steatosis or Nonalcoholic Fatty Liver. | 2019 | Details |
| A07661 | 32405181 | J Clin Exp Hepatol | Natural History of Non-Alcoholic Fatty Liver Disease: A Study With Paired Liver Biopsies. | 2019 | Details |
| A07662 | 32405180 | J Clin Exp Hepatol | Effect of Donor Hepatic Steatosis on Ischemia Reperfusion Injury in Liver Transplant Recipient. | 2019 | Details |
| A07663 | 32405177 | J Clin Exp Hepatol | NASH-inducing Diets in Göttingen Minipigs. | 2019 | Details |
| A07664 | 32404278 | Biochim Biophys Acta Mol Cell Biol Lipids | Niacin increases diet-induced hepatic steatosis in B6129 mice. | 2020 | Details |
| A07665 | 32403970 | Autophagy | MLKL contributes to Western diet-induced liver injury through inhibiting autophagy. | 2020 | Details |
| A07666 | 32403887 | Zhonghua Gan Zang Bing Za Zhi | [Discussion on the curative effect and mechanisms of berberine in rats with non-alcoholic fatty liver]. | 2020 | Details |
| A07667 | 32403305 | Antioxidants (Basel) | The Hepatoprotective Effect of Taurisolo, a Nutraceutical Enriched in Resveratrol and Polyphenols, Involves Activation of Mitochondrial Metabolism in Mice Liver. | 2020 | Details |
| A07668 | 32402090 | Aliment Pharmacol Ther | Review article: COVID-19 and liver disease-what we know on 1st May 2020. | 2020 | Details |
| A07669 | 32401929 | Braz J Med Biol Res | A Brazilian regional basic diet-induced chronic malnutrition drives liver inflammation with higher ApoA-I activity in C57BL6J mice. | 2020 | Details |
| A07670 | 32401092 | Infect Dis (Lond) | Changing indications for liver transplant: slow decline of hepatitis viruses in Italy. | 2020 | Details |
| A07671 | 32399892 | Endocrine | Albumin binding function is a novel biomarker for early liver damage and disease progression in non-alcoholic fatty liver disease. | 2020 | Details |
| A07672 | 32398673 | Nat Commun | Hepatocyte mitochondria-derived danger signals directly activate hepatic stellate cells and drive progression of liver fibrosis. | 2020 | Details |
| A07673 | 32398489 | Eur J Gastroenterol Hepatol | Optimal thresholds for ultrasound attenuation parameter in the evaluation of hepatic steatosis severity: evidence from a cohort of patients with biopsy-proven fatty liver disease. | 2021 | Details |
| A07674 | 32396918 | Urol Int | Impact of Androgen Deprivation Therapy on Non-Alcoholic Fatty Liver Disease in Patients with Prostate Cancer: A CT Evaluation. | 2020 | Details |
| A07675 | 32396836 | Trends Genet | The Epigenetic Drug Discovery Landscape for Metabolic-associated Fatty Liver Disease. | 2020 | Details |
| A07676 | 32396530 | J Clin Invest | Nonalcoholic fatty liver disease in CLOCK mutant mice. | 2020 | Details |
| A07677 | 32396414 | Aging Male | Non-invasive diagnosis of nonalcoholic fatty liver disease: impact of age and other risk factors. | 2020 | Details |
| A07678 | 32396388 | Am J Physiol Endocrinol Metab | β-Hydroxybutyrate is reduced in humans with obesity-related NAFLD and displays a dose-dependent effect on skeletal muscle mitochondrial respiration in vitro. | 2020 | Details |
| A07679 | 32394476 | Hepatology | Hepatic Molecular Signatures Highlight the Sexual Dimorphism of Nonalcoholic Steatohepatitis (NASH). | 2020 | Details |
| A07680 | 32392802 | Int J Mol Sci | Short-Term Western Diet Aggravates Non-Alcoholic Fatty Liver Disease (NAFLD) With Portal Hypertension in TGR(mREN2)27 Rats. | 2020 | Details |
| A07681 | 32392712 | J Clin Med | A Role for Gut Microbiome Fermentative Pathways in Fatty Liver Disease Progression. | 2020 | Details |
| A07683 | 32392051 | J Med Chem | 6-Amino[1,2,5]oxadiazolo[3,4-b]pyrazin-5-ol Derivatives as Efficacious Mitochondrial Uncouplers in STAM Mouse Model of Nonalcoholic Steatohepatitis. | 2020 | Details |
| A07685 | 32390839 | Front Pharmacol | Hepatoprotective and Anti-Oxidative Effects of Total Flavonoids From Qu Zhi Qiao (Fruit of Citrus Paradisi cv.Changshanhuyou) on Nonalcoholic Steatohepatitis In Vivo and In Vitro Through Nrf2-ARE Signaling Pathway. | 2020 | Details |
| A07686 | 32390701 | World J Gastroenterol | Therapeutic advances in non-alcoholic fatty liver disease: A microbiota-centered view. | 2020 | Details |
| A07687 | 32390698 | World J Gastroenterol | Macrophages in metabolic associated fatty liver disease. | 2020 | Details |
| A07688 | 32390496 | Lupus | Hepatic manifestations in systemic lupus erythematosus. | 2020 | Details |
| A07689 | 32390455 | Antioxid Redox Signal | Intestinal Dysbiosis and Development of Cardiometabolic Disorders in Childhood Cancer Survivors: A Critical Review. | 2020 | Details |
| A07690 | 32390388 | Clin Lab | Plasma miR-513a-5p as a Potential Biomarker for Diagnosis of Nonalcoholic Fatty Liver Disease in Type 2 Diabetes Mellitus Patients. | 2020 | Details |
| A07691 | 32390378 | Clin Lab | Plasma Levels and Gene Expression of RANK in Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A07693 | 32389886 | Clin Gastroenterol Hepatol | Type 2 Diabetes and Metformin Use Associate With Outcomes of Patients With Nonalcoholic Steatohepatitis-Related, Child-Pugh A Cirrhosis. | 2020 | Details |
| A07694 | 32389170 | Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi | [Inulin increases the proportion of monocytic myeloid-derived suppressor cells in peripheral blood, liver, spleen and regulates the secretion of plasma inflammatory cytokines in mice with non-alcoholic fatty liver disease]. | 2020 | Details |
| A07695 | 32389004 | Ann Palliat Med | Blueberry polyphenols play a preventive effect on alcoholic fatty liver disease C57BL/6 J mice by promoting autophagy to accelerate lipolysis to eliminate excessive TG accumulation in hepatocytes. | 2020 | Details |
| A07696 | 32388251 | J Nutr Biochem | Olanzapine-induced liver injury in mice: aggravation by high-fat diet and protection with sulforaphane. | 2020 | Details |
| A07697 | 32388250 | J Nutr Biochem | Targeting the gut microbiota with resveratrol: a demonstration of novel evidence for the management of hepatic steatosis. | 2020 | Details |
| A07698 | 32387861 | Biomed Pharmacother | 2,3,5,4'-tetrahydroxystilbence-2-O-β-D-glucoside attenuates hepatic steatosis via IKKβ/NF-κB and Keap1-Nrf2 pathways in larval zebrafish. | 2020 | Details |
| A07699 | 32387461 | J Ethnopharmacol | Ginsenoside Mc1 improves liver steatosis and insulin resistance by attenuating ER stress. | 2020 | Details |
| A07700 | 32387227 | Metabolism | Advances in non-invasive biomarkers for the diagnosis and monitoring of non-alcoholic fatty liver disease. | 2020 | Details |
| A07701 | 32386798 | Clin Res Hepatol Gastroenterol | LUM is the hub gene of advanced fibrosis in nonalcoholic fatty liver disease patients. | 2020 | Details |
| A07702 | 32386450 | Liver Int | The PNPLA3-I148M variant increases polyunsaturated triglycerides in human adipose tissue. | 2020 | Details |
| A07703 | 32385406 | Sci Rep | Pemafibrate, a selective PPARα modulator, prevents non-alcoholic steatohepatitis development without reducing the hepatic triglyceride content. | 2020 | Details |
| A07704 | 32384593 | Nutrients | Beyond Body Weight-Loss: Dietary Strategies Targeting Intrahepatic Fat in NAFLD. | 2020 | Details |
| A07705 | 32384501 | Medicine (Baltimore) | Vitamin D supplementation for nonalcoholic fatty liver disease in type 2 diabetes mellitus: A protocol for a systematic review and meta-analysis. | 2020 | Details |
| A07706 | 32383865 | J Agric Food Chem | Protective Mechanism of Common Buckwheat (Fagopyrum esculentum Moench.) against Nonalcoholic Fatty Liver Disease Associated with Dyslipidemia in Mice Fed a High-Fat and High-Cholesterol Diet. | 2020 | Details |
| A07707 | 32383295 | Aliment Pharmacol Ther | Review article: the emerging role of genetics in precision medicine for patients with non-alcoholic steatohepatitis. | 2020 | Details |
| A07708 | 32382557 | Biomed Res Int | A Candidate Drug for Nonalcoholic Fatty Liver Disease: A Review of Pharmacological Activities of Polygoni Multiflori Radix. | 2020 | Details |
| A07709 | 32382414 | Biomed Rep | Diet induces hepatocyte protection in fatty liver disease via modulation of PTEN signaling. | 2020 | Details |
| A07710 | 32382264 | Gastroenterol Res Pract | Interface Hepatitis over Grade 2 May Differentiate Chronic Inflammation Associated with CHB from NAFLD in the Early Stage. | 2020 | Details |
| A07711 | 32382087 | Sci Rep | Enhanced insulin receptor interaction by a bifunctional insulin-transferrin fusion protein: an approach to overcome insulin resistance. | 2020 | Details |
| A07712 | 32381514 | Gut | Combination therapy for non-alcoholic steatohepatitis: rationale, opportunities and challenges. | 2020 | Details |
| A07713 | 32381466 | J Pediatr | Glomerular Hyperfiltration Is Associated with Liver Disease Severity in Children with Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A07714 | 32380876 | J Med Food | Beneficial Effects of Insect Extracts on Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A07715 | 32378295 | Liver Int | Mesenchymal iron deposition is associated with adverse long-term outcome in non-alcoholic fatty liver disease. | 2020 | Details |
| A07716 | 32378092 | J Gastrointest Surg | Impact of Type 2 Diabetes on Oncologic Outcomes of Hepatocellular Carcinomas in Non-Cirrhotic, Non-alcoholic Steatohepatitis: a Matched-Pair Analysis. | 2020 | Details |
| A07717 | 32377814 | Eur Radiol | Liver extracellular volume fraction values obtained with magnetic resonance imaging can quantitatively stage liver fibrosis: a validation study in monkeys with nonalcoholic steatohepatitis. | 2020 | Details |
| A07718 | 32377366 | BMJ Open Gastroenterol | Antitumour necrosis factor-α agents and development of new-onset cirrhosis or non-alcoholic fatty liver disease: a retrospective cohort. | 2020 | Details |
| A07719 | 32376415 | J Hepatol | Immunity-related GTPase induces lipophagy to prevent excess hepatic lipid accumulation. | 2020 | Details |
| A07720 | 32376414 | J Hepatol | Acetyl-CoA carboxylase inhibition disrupts metabolic reprogramming during hepatic stellate cell activation. | 2020 | Details |
| A07722 | 32376267 | Life Sci | Heme oxygenase-1 alleviated non-alcoholic fatty liver disease via suppressing ROS-dependent endoplasmic reticulum stress. | 2020 | Details |
| A07723 | 32376236 | Ann Hepatol | Blood lead level is associated with advanced liver fibrosis in patients with non-alcoholic fatty liver disease: A nationwide survey (NHANES 2011-2016). | 2020 | Details |
| A07724 | 32375660 | BMC Gastroenterol | Association between NAFLD and risk of prevalent chronic kidney disease: why there is a difference between east and west? | 2020 | Details |
| A07725 | 32375340 | Int J Mol Sci | Coenzyme Q10 Supplementation Improves Adipokine Levels and Alleviates Inflammation and Lipid Peroxidation in Conditions of Metabolic Syndrome: A Meta-Analysis of Randomized Controlled Trials. | 2020 | Details |
| A07726 | 32375182 | Horm Metab Res | Liraglutide Ameliorates Lipotoxicity-Induced Oxidative Stress by Activating the NRF2 Pathway in HepG2 Cells. | 2020 | Details |
| A07727 | 32375062 | Cell Metab | Low-Dose Sorafenib Acts as a Mitochondrial Uncoupler and Ameliorates Nonalcoholic Steatohepatitis. | 2020 | Details |
| A07728 | 32374676 | Am J Physiol Cell Physiol | New aspects of hepatic endothelial cells in physiology and nonalcoholic fatty liver disease. | 2020 | Details |
| A07730 | 32373514 | Front Oncol | Sirt4: A Multifaceted Enzyme at the Crossroads of Mitochondrial Metabolism and Cancer. | 2020 | Details |
| A07731 | 32373213 | Theranostics | PTPROt aggravates inflammation by enhancing NF-κB activation in liver macrophages during nonalcoholic steatohepatitis. | 2020 | Details |
| A07732 | 32372515 | Aliment Pharmacol Ther | Nonalcoholic fatty liver disease progression rates to cirrhosis and progression of cirrhosis to decompensation and mortality: a real world analysis of Medicare data. | 2020 | Details |
| A07733 | 32372205 | Abdom Radiol (NY) | Hepatocellular carcinoma in non-cirrhotic versus cirrhotic liver: a clinico-radiological comparative analysis. | 2020 | Details |
| A07734 | 32372191 | Dig Dis Sci | G-Protein-Coupled Receptors 120 Agonist III Improves Hepatic Inflammation and ER Stress in Steatohepatitis. | 2020 | Details |
| A07735 | 32371503 | BMJ Open Gastroenterol | SIRT1-dependent mechanisms and effects of resveratrol for amelioration of muscle wasting in NASH mice. | 2020 | Details |
| A07736 | 32370702 | Protein Pept Lett | Adipokines: A Rainbow of Proteins with Metabolic and Endocrine Functions. | 2020 | Details |
| A07737 | 32370249 | Biology (Basel) | The Role of the Histone Methyltransferase EZH2 in Liver Inflammation and Fibrosis in STAM NASH Mice. | 2020 | Details |
| A07738 | 32369900 | J Clin Med | Inhibition of Protein-tyrosine Phosphatase PTP1B and LMPTP Promotes Palmitate/Oleate-challenged HepG2 Cell Survival by Reducing Lipoapoptosis, Improving Mitochondrial Dynamics and Mitigating Oxidative and Endoplasmic Reticulum Stress. | 2020 | Details |
| A07739 | 32369776 | J Endocrinol | Oxygen therapy alleviates hepatic steatosis by inhibiting hypoxia-inducible factor-2α. | 2020 | Details |
| A07740 | 32369237 | J Dig Dis | Epidemiology of nonalcoholic fatty liver disease in non-obese populations: Meta-analytic assessment of its prevalence, genetic, metabolic, and histological profiles. | 2020 | Details |
| A07743 | 32368113 | Diabetes Metab Syndr Obes | Common and Unique Factors and the Bidirectional Relationship Between Chronic Kidney Disease and Nonalcoholic Fatty Liver in Type 2 Diabetes Patients. | 2020 | Details |
| A07744 | 32367624 | Pediatr Obes | Increased atherogenic lipoprotein profile in children with non-alcoholic steatohepatitis. | 2020 | Details |
| A07745 | 32366854 | Sci Rep | Novel Combinatorial Regimen of Garcinol and Curcuminoids for Non-alcoholic Steatohepatitis (NASH) in Mice. | 2020 | Details |
| A07746 | 32366600 | J Pharmacol Exp Ther | Ezetimibe Markedly Reduces Hepatic Triglycerides and Cholesterol in Rats Fed on Fish Oil by Increasing the Expression of Cholesterol Efflux Transporters. | 2020 | Details |
| A07747 | 32365683 | Nutrients | Association of the SH2B1 rs7359397 Gene Polymorphism with Steatosis Severity in Subjects with Obesity and Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A07748 | 32365632 | Cells | L-Selectin/CD62L is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men. | 2020 | Details |
| A07749 | 32365537 | Cells | EX-527 Prevents the Progression of High-Fat Diet-Induced Hepatic Steatosis and Fibrosis by Upregulating SIRT4 in Zucker Rats. | 2020 | Details |
| A07750 | 32365405 | J Gastroenterol Hepatol | Periostin antisense oligonucleotide prevents hepatic steatosis and fibrosis in a mouse model of non-alcoholic steatohepatitis. | 2020 | Details |
| A07751 | 32365055 | J Clin Invest | Hepatic Slug epigenetically promotes liver lipogenesis, fatty liver disease, and type 2 diabetes. | 2020 | Details |
| A07752 | 32364539 | J Clin Invest | Insulin-stimulated lipogenesis gets an epigenetic makeover. | 2020 | Details |
| A07753 | 32363890 | Am J Physiol Gastrointest Liver Physiol | Immune modulating effects of additional supplementation of estradiol combined with testosterone in murine testosterone-deficient NAFLD model. | 2020 | Details |
| A07754 | 32363684 | Aliment Pharmacol Ther | Outcomes after hepatic encephalopathy in population-based cohorts of patients with cirrhosis. | 2020 | Details |
| A07755 | 32363679 | Diabetes Obes Metab | Intrahepatic fat, irrespective of ethnicity, is associated with reduced endogenous insulin clearance and hepatic insulin resistance in obese youths: A cross-sectional and longitudinal study from the Yale Pediatric NAFLD cohort. | 2020 | Details |
| A07756 | 32363320 | Hepatol Commun | Validation of PAS Kinase, a Regulator of Hepatic Fatty Acid and Triglyceride Synthesis, as a Therapeutic Target for Nonalcoholic Steatohepatitis. | 2020 | Details |
| A07757 | 32363319 | Hepatol Commun | High Protein Intake Is Associated With Histological Disease Activity in Patients With NAFLD. | 2020 | Details |
| A07758 | 32363318 | Hepatol Commun | Differential Associations of Circulating MicroRNAs With Pathogenic Factors in NAFLD. | 2020 | Details |
| A07759 | 32362966 | Gastroenterology Res | Benefits of the Therapy With Abexol in Patients With Non-Alcoholic Fatty Liver Disease. | 2020 | Details |