Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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insulin resistance7794 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A52461 | 26893932 | Clin Hypertens | Change in fatty liver status and 5-year risk of incident metabolic syndrome: a retrospective cohort study. | 2015 | Details |
| A52462 | 26865583 | Eur J Endocrinol | EJE PRIZE 2015: How does insulin resistance arise, and how does it cause disease? Human genetic lessons. | 2016 | Details |
| A52465 | 26777475 | Nutr Metab Cardiovasc Dis | Subclinical atherosclerosis is associated with Epicardial Fat Thickness and hepatic steatosis in the general population. | 2015 | Details |
| A52469 | 26652506 | Expert Rev Clin Pharmacol | Fatty liver in adults receiving antiepileptic medications: relationship to the metabolic risks. | 2016 | Details |
| A52472 | 26608809 | Exp Gerontol | The presence of the ovary prevents hepatic mitochondrial oxidative stress in young and aged female mice through glutathione peroxidase 1. | 2015 | Details |
| A52473 | 26608096 | J Physiol | The roles of c-Jun NH2-terminal kinases (JNKs) in obesity and insulin resistance. | 2015 | Details |
| A52474 | 26603189 | Cell Metab | Fetuin B Is a Secreted Hepatocyte Factor Linking Steatosis to Impaired Glucose Metabolism. | 2015 | Details |
| A52476 | 26562264 | Endocrinology | Androgen Deficiency Exacerbates High-Fat Diet-Induced Metabolic Alterations in Male Mice. | 2015 | Details |
| A52486 | 26464614 | Int J Clin Exp Pathol | Lipid droplet-associated proteins in alcoholic liver disease: a potential linkage with hepatocellular damage. | 2015 | Details |
| A52489 | 26439088 | J Clin Endocrinol Metab | The Genetic Variant I148M in PNPLA3 Is Associated With Increased Hepatic Retinyl-Palmitate Storage in Humans. | 2015 | Details |
| A52490 | 26423886 | J Nutr Biochem | Berry intake changes hepatic gene expression and DNA methylation patterns associated with high-fat diet. | 2015 | Details |
| A52492 | 26414730 | Curr Med Res Opin | Why focus on uric acid? | 2015 | Details |
| A52494 | 26382148 | J Vis Exp | Determination of Fatty Acid Oxidation and Lipogenesis in Mouse Primary Hepatocytes. | 2015 | Details |
| A52495 | 26376619 | Crit Rev Clin Lab Sci | Sugar consumption, metabolic disease and obesity: The state of the controversy. | 2015 | Details |
| A52497 | 26344102 | Cell Metab | Celastrol Protects against Obesity and Metabolic Dysfunction through Activation of a HSF1-PGC1α Transcriptional Axis. | 2015 | Details |
| A52498 | 26337697 | Obes Surg | Changes in Bile Acid Profile After Laparoscopic Sleeve Gastrectomy are Associated with Improvements in Metabolic Profile and Fatty Liver Disease. | 2016 | Details |
| A52499 | 26336158 | J Mol Endocrinol | Truncation of POC1A associated with short stature and extreme insulin resistance. | 2015 | Details |
| A52505 | 26256894 | Ann Hepatol | Fatty liver and abdominal fat relationships with high C-reactive protein in adults without coronary heart disease. | 2016 | Details |
| A52507 | 26252778 | PLoS One | 1H-MRS Measured Ectopic Fat in Liver and Muscle in Danish Lean and Obese Children and Adolescents. | 2015 | Details |
| A52513 | 26171768 | Aging Male | Connections between lower urinary tract symptoms related to benign prostatic enlargement and metabolic syndrome with its components: a systematic review and meta-analysis. | 2015 | Details |
| A52515 | 26152236 | J Agric Food Chem | Dietary (-)-Epigallocatechin-3-gallate Supplementation Counteracts Aging-Associated Skeletal Muscle Insulin Resistance and Fatty Liver in Senescence-Accelerated Mouse. | 2015 | Details |
| A52517 | 26119995 | Int J Obes (Lond) | Leptin-induced mitochondrial fusion mediates hepatic lipid accumulation. | 2015 | Details |
| A52518 | 26112408 | J Biol Chem | Lipid-induced Muscle Insulin Resistance Is Mediated by GGPPS via Modulation of the RhoA/Rho Kinase Signaling Pathway. | 2015 | Details |
| A52522 | 26097021 | Obesity (Silver Spring) | Protection from diet-induced obesity and insulin resistance in mice lacking CCL19-CCR7 signaling. | 2015 | Details |
| A52523 | 26059381 | Nutrition | Conjugated linoleic acid reduces visceral and ectopic lipid accumulation and insulin resistance in chronic severe hypertriacylglycerolemia. | 2015 | Details |
| A52528 | 25972231 | Diabetologia | Oncostatin M is a potential agent for the treatment of obesity and related metabolic disorders: a study in mice. | 2015 | Details |
| A52532 | 25916863 | Eur J Nutr | Labrador tea (Rhododendron groenlandicum) attenuates insulin resistance in a diet-induced obesity mouse model. | 2015 | Details |
| A52533 | 25906681 | Biochim Biophys Acta | Fenofibrate insulates diacylglycerol in lipid droplet/ER and preserves insulin signaling transduction in the liver of high fat fed mice. | 2015 | Details |
| A52537 | 25895678 | Cell Physiol Biochem | Mice Lacking Free Fatty Acid Receptor 1 (GPR40/FFAR1) are Protected Against Conjugated Linoleic Acid-Induced Fatty Liver but Develop Inflammation and Insulin Resistance in the Brain. | 2015 | Details |
| A52538 | 25854303 | Endocrine | Short-term administration of GW501516 improves inflammatory state in white adipose tissue and liver damage in high-fructose-fed mice through modulation of the renin-angiotensin system. | 2015 | Details |
| A52541 | 25805830 | FASEB J | Activated Kupffer cells inhibit insulin sensitivity in obese mice. | 2015 | Details |
| A52542 | 25766534 | Cell Physiol Biochem | Increased oxidative stress and mitochondrial dysfunction in zucker diabetic rat liver and brain. | 2015 | Details |
| A52544 | 25749935 | J Physiol Biochem | Gut microbiota: a key player in health and disease. A review focused on obesity. | 2015 | Details |
| A52545 | 25745813 | Gen Comp Endocrinol | Histomorphology of the bottlenose dolphin (Tursiops truncatus) pancreas and association of increasing islet β-cell size with chronic hypercholesterolemia. | 2015 | Details |
| A52546 | 25736229 | Obes Surg | Sleeve Gastrectomy Reduces Hepatic Steatosis by Improving the Coordinated Regulation of Aquaglyceroporins in Adipose Tissue and Liver in Obese Rats. | 2015 | Details |
| A52547 | 25723909 | Appl Physiol Nutr Metab | Carnitine supplementation alleviates lipid metabolism derangements and protects against oxidative stress in non-obese hereditary hypertriglyceridemic rats. | 2015 | Details |
| A52548 | 25723054 | Scand J Clin Lab Invest | Serum fetuin-A and arginase-1 in human obesity model: Is there any interaction between inflammatory status and arginine metabolism? | 2015 | Details |
| A52549 | 25695383 | Rev Invest Clin | Association of fatty liver with cardiovascular risk factors and subclinical atherosclerosis in a Mexican population. | 2015 | Details |
| A52552 | 25675425 | Pediatr Res | IUGR with infantile overnutrition programs an insulin-resistant phenotype through DNA methylation of peroxisome proliferator-activated receptor-γ coactivator-1α in rats. | 2015 | Details |
| A52553 | 25658017 | J Clin Endocrinol Metab | Subchronic sleep restriction causes tissue-specific insulin resistance. | 2015 | Details |
| A52554 | 25656826 | Trends Endocrinol Metab | Adipocytokines and hepatic fibrosis. | 2015 | Details |
| A52556 | 25638597 | Nutr Metab Cardiovasc Dis | Consumption of a whey protein-enriched diet may prevent hepatic steatosis associated with weight gain in elderly women. | 2014 | Details |
| A52558 | 25632931 | Semin Liver Dis | MicroRNAs in fatty liver disease. | 2015 | Details |
| A52559 | 25628422 | Am J Physiol Endocrinol Metab | Myeloid cell TRAF3 promotes metabolic inflammation, insulin resistance, and hepatic steatosis in obesity. | 2015 | Details |
| A52563 | 25592279 | Mol Biosyst | Dissection of metabolic pathways in the Db/Db mouse model by integrative proteome and acetylome analysis. | 2015 | Details |
| A52570 | 25487878 | Sci Rep | Protopanaxatriol, a novel PPARγ antagonist from Panax ginseng, alleviates steatosis in mice. | 2014 | Details |
| A52575 | 25443347 | J Hepatol | Facts and fictions of HCV and comorbidities: steatosis, diabetes mellitus, and cardiovascular diseases. | 2014 | Details |
| A52583 | 25376159 | J Gastroenterol Hepatol | Hepatic fat, not visceral fat, is associated with gallbladder polyps: a study of 2643 healthy subjects. | 2015 | Details |
| A52584 | 25367448 | BMC Med | FTO rs9939609 polymorphism is associated with metabolic disturbances and response to HCV therapy in HIV/HCV-coinfected patients. | 2014 | Details |
| A52587 | 25329603 | Nutr Diabetes | Altered levels of serum sphingomyelin and ceramide containing distinct acyl chains in young obese adults. | 2014 | Details |
| A52588 | 25295789 | Cell Metab | CerS2 haploinsufficiency inhibits β-oxidation and confers susceptibility to diet-induced steatohepatitis and insulin resistance. | 2014 | Details |
| A52589 | 25294945 | Diabetes | Anti-CD44 antibody treatment lowers hyperglycemia and improves insulin resistance, adipose inflammation, and hepatic steatosis in diet-induced obese mice. | 2014 | Details |
| A52590 | 25294012 | Endocrine | Prediabetes and associated disorders. | 2014 | Details |
| A52594 | 25203718 | Hepatology | Effect of sofosbuvir and ribavirin treatment on peripheral and hepatic lipid metabolism in chronic hepatitis C virus, genotype 1-infected patients. | 2015 | Details |
| A52595 | 25190687 | Nutr Clin Pract | Nutrition status of patients with chronic hepatitis B or C. | 2014 | Details |
| A52600 | 25092429 | J Gastroenterol Hepatol | Hepatitis B virus infection and metabolic syndrome: fact or fiction? | 2015 | Details |
| A52602 | 25053728 | Eur J Endocrinol | Fatty liver largely explains associations of subclinical hypothyroidism with insulin resistance, metabolic syndrome, and subclinical coronary atherosclerosis. | 2014 | Details |
| A52603 | 25034291 | Dig Dis | Adipocyte cell death, fatty liver disease and associated metabolic disorders. | 2014 | Details |
| A52604 | 25017306 | Mol Immunol | The complement system in human cardiometabolic disease. | 2014 | Details |
| A52605 | 25013400 | J Biomed Res | Rab proteins implicated in lipid storage and mobilization. | 2014 | Details |
| A52607 | 24991042 | J Nutr | High-viscosity dietary fibers reduce adiposity and decrease hepatic steatosis in rats fed a high-fat diet. | 2014 | Details |
| A52616 | 24834723 | Ukr Biochem J | [The effect of N-stearoylethanolamine on liver phospholipid composition of rats with insulin resistance caused by alimentary obesity]. | 2014 | Details |
| A52617 | 24799023 | Horm Metab Res | Systemic metabolic signaling in acute and chronic gastrointestinal inflammation of inflammatory bowel diseases. | 2014 | Details |
| A52619 | 24756314 | Metab Brain Dis | Myeloid-specific deletion of SIRT1 increases hepatic steatosis and hypothalamic inflammation in mice fed a high-fat diet. | 2014 | Details |
| A52622 | 24679404 | Animal | Reproductive tract inflammatory disease in postpartum dairy cows. | 2014 | Details |
| A52623 | 24678942 | Ren Fail | The association between renal stone disease and cholesterol gallstones: the easy to believe and not hard to retrieve theory of the metabolic syndrome. | 2014 | Details |
| A52624 | 24659875 | World J Gastroenterol | Hepatitis C virus and metabolic disorder interactions towards liver damage and atherosclerosis. | 2014 | Details |
| A52627 | 24613289 | Mayo Clin Proc | Ethnic and sex differences in fatty liver on cardiac computed tomography: the multi-ethnic study of atherosclerosis. | 2014 | Details |
| A52631 | 24486395 | Eur J Pharmacol | Silymarin ameliorates fructose induced insulin resistance syndrome by reducing de novo hepatic lipogenesis in the rat. | 2014 | Details |
| A52634 | 24447068 | Metab Syndr Relat Disord | Metabolic syndrome in Turner syndrome and relation between body composition and clinical, genetic, and ultrasonographic characteristics. | 2014 | Details |
| A52635 | 24438728 | Prog Cardiovasc Dis | Overview of epidemiology and contribution of obesity to cardiovascular disease. | 2013 | Details |
| A52637 | 24400816 | BMC Public Health | Beyond BMI: The "Metabolically healthy obese" phenotype & its association with clinical/subclinical cardiovascular disease and all-cause mortality -- a systematic review. | 2014 | Details |
| A52638 | 24333420 | Biochem Biophys Res Commun | 8-Oxo-2'-deoxyguanosine ameliorates features of metabolic syndrome in obese mice. | 2013 | Details |
| A52642 | 24281976 | Curr Cardiol Rep | Impact of obesity and bariatric surgery on metabolism and coronary circulatory function. | 2014 | Details |
| A52643 | 24260478 | PLoS One | Deep sequencing of small RNA repertoires in mice reveals metabolic disorders-associated hepatic miRNAs. | 2013 | Details |
| A52649 | 24187406 | J Clin Endocrinol Metab | Toll-like receptor status in obesity and metabolic syndrome: a translational perspective. | 2013 | Details |
| A52655 | 24101915 | Front Endocrinol (Lausanne) | Development and application of specific cytokine assays in tissue samples from a bottlenose dolphin with hyperinsulinemia. | 2013 | Details |
| A52659 | 24025398 | Circ J | Expanding role of delta-like 4 mediated notch signaling in cardiovascular and metabolic diseases. | 2013 | Details |
| A52660 | 24012029 | Am J Cardiol | Relation of hepatic steatosis to atherogenic dyslipidemia. | 2013 | Details |
| A52665 | 23954796 | J Am Heart Assoc | Hepatic extracellular signal-regulated kinase 2 suppresses endoplasmic reticulum stress and protects from oxidative stress and endothelial dysfunction. | 2013 | Details |
| A52666 | 23941362 | Nutr J | Effects of lifestyle changes including specific dietary intervention and physical activity in the management of patients with chronic hepatitis C--a randomized trial. | 2013 | Details |
| A52668 | 23886976 | Benef Microbes | Gut microbiota controls adipose tissue expansion, gut barrier and glucose metabolism: novel insights into molecular targets and interventions using prebiotics. | 2014 | Details |
| A52671 | 23824421 | J Clin Endocrinol Metab | Metabolic consequences of adipose triglyceride lipase deficiency in humans: an in vivo study in patients with neutral lipid storage disease with myopathy. | 2013 | Details |
| A52672 | 23809427 | Metabolism | Association of estrogen receptor alpha gene polymorphisms with metabolic syndrome in Egyptian women. | 2013 | Details |
| A52674 | 23769925 | Gene | The C57BL/6J Niemann-Pick C1 mouse model with decreased gene dosage has impaired glucose tolerance independent of body weight. | 2013 | Details |
| A52677 | 23697588 | Obes Res Clin Pract | Ethnic difference in liver fat content: a cross-sectional observation among Japanese American in Hawaii, Japanese in Japan, and non-Hispanic whites in United States. | 2013 | Details |
| A52685 | 23551521 | J Intern Med | Ectopic lipid storage and insulin resistance: a harmful relationship. | 2013 | Details |
| A52686 | 23550081 | Endocr Rev | Adiposity and insulin resistance in humans: the role of the different tissue and cellular lipid depots. | 2013 | Details |
| A52689 | 23510830 | Atherosclerosis | Enhanced adiponectin actions by overexpression of adiponectin receptor 1 in macrophages. | 2013 | Details |
| A52690 | 23509418 | Mediators Inflamm | Lipotoxicity: effects of dietary saturated and transfatty acids. | 2013 | Details |
| A52693 | 23445230 | Expert Rev Gastroenterol Hepatol | The predictive value of steatosis in hepatitis C virus infection. | 2013 | Details |
| A52694 | 23431266 | PLoS Biol | Partial inhibition of adipose tissue lipolysis improves glucose metabolism and insulin sensitivity without alteration of fat mass. | 2013 | Details |
| A52696 | 23398239 | Alcohol Clin Exp Res | Temporal effects of ethanol consumption on energy homeostasis, hepatic steatosis, and insulin sensitivity in mice. | 2013 | Details |
| A52701 | 23317789 | Prog Mol Biol Transl Sci | Adiponectin receptors in energy homeostasis and obesity pathogenesis. | 2013 | Details |
| A52702 | 23303913 | Physiol Rev | Pathophysiology of human visceral obesity: an update. | 2013 | Details |
| A52704 | 23250359 | Diabetes | Angiotensin 1-7 as means to prevent the metabolic syndrome: lessons from the fructose-fed rat model. | 2012 | Details |
| A52707 | 23176795 | Nutr Res | Genistein reduced insulin resistance index through modulating lipid metabolism in ovariectomized rats. | 2012 | Details |
| A52709 | 23128765 | Nestle Nutr Inst Workshop Ser | Targeting adipose tissue inflammation to treat the underlying basis of the metabolic complications of obesity. | 2012 | Details |
| A52712 | 23047931 | Endocr Pract | Development of type 2 diabetes mellitus in the obese adolescent: a growing challenge. | 2013 | Details |
| A52714 | 23043895 | Trends Endocrinol Metab | Dissociating fatty liver and diabetes. | 2012 | Details |