Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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insulin resistance7794 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A52934 | 19349323 | Circulation | Pioglitazone improves cardiac function and alters myocardial substrate metabolism without affecting cardiac triglyceride accumulation and high-energy phosphate metabolism in patients with well-controlled type 2 diabetes mellitus. | 2009 | Details |
| A52936 | 19292832 | Aliment Pharmacol Ther | Influence of insulin resistance on hepatic fibrosis and steatosis in hepatitis C virus (HCV) mono-infected compared with HIV-HCV co-infected patients. | 2009 | Details |
| A52937 | 19277603 | Diabetologia | Inhibition of the chemokine (C-C motif) ligand 2/chemokine (C-C motif) receptor 2 pathway attenuates hyperglycaemia and inflammation in a mouse model of hepatic steatosis and lipoatrophy. | 2009 | Details |
| A52940 | 19259639 | J Mol Med (Berl) | Elovl6: a new player in fatty acid metabolism and insulin sensitivity. | 2009 | Details |
| A52941 | 19148799 | J Gastroenterol | Steatosis, liver injury, and hepatocarcinogenesis in hepatitis C viral infection. | 2009 | Details |
| A52946 | 19148125 | Obesity (Silver Spring) | Prevention and reversal of obesity and glucose intolerance in mice by DHA derivatives. | 2009 | Details |
| A52950 | 19053047 | Hepatology | Differential effects of JNK1 and JNK2 inhibition on murine steatohepatitis and insulin resistance. | 2009 | Details |
| A52958 | 18846047 | Obesity (Silver Spring) | Obesity upregulates genes involved in oxidative phosphorylation in livers of diabetic patients. | 2008 | Details |
| A52961 | 18773755 | G Ital Cardiol (Rome) | [Pharmacological therapy of obesity]. | 2008 | Details |
| A52964 | 18716169 | J Nutr | The major green tea polyphenol, (-)-epigallocatechin-3-gallate, inhibits obesity, metabolic syndrome, and fatty liver disease in high-fat-fed mice. | 2008 | Details |
| A52969 | 18633113 | Diabetes | Plasma fetuin-A levels and the risk of type 2 diabetes. | 2008 | Details |
| A52970 | 18630061 | Rev Med Suisse | [Metabolic syndrome, a mitochondrial disease?]. | 2008 | Details |
| A52971 | 18619057 | Gac Med Mex | [Obesity, inflammation and diabetes]. | 2008 | Details |
| A52972 | 18596860 | Trans Am Clin Climatol Assoc | Fatty liver and insulin resistance: not always linked. | 2008 | Details |
| A52975 | 18497882 | J Clin Invest | Overindulgence and metabolic syndrome: is FoxO1 a missing link? | 2008 | Details |
| A52978 | 18446001 | Endocr J | Molecular mechanism of moderate insulin resistance in adiponectin-knockout mice. | 2008 | Details |
| A52980 | 18436717 | Clin Chem | The perfect storm: obesity, adipocyte dysfunction, and metabolic consequences. | 2008 | Details |
| A52982 | 18366118 | Hepatology | Steatohepatitis: Risk factors and impact on disease severity in human immunodeficiency virus/hepatitis C virus coinfection. | 2008 | Details |
| A52983 | 18335040 | PLoS One | Fetuin-A induces cytokine expression and suppresses adiponectin production. | 2008 | Details |
| A52987 | 18230901 | Front Horm Res | 11beta-hydroxysteroid dehydrogenase type 1 and obesity. | 2008 | Details |
| A52989 | 18220945 | Endocr Metab Immune Disord Drug Targets | Does global gene expression analysis in type 2 diabetes provide an opportunity to identify highly promising drug targets? | 2007 | Details |
| A52990 | 18220654 | Curr Diabetes Rev | Peroxisome proliferator-activated receptor (PPAR) in metabolic syndrome and type 2 diabetes mellitus. | 2007 | Details |
| A52991 | 18185059 | Curr Opin Endocrinol Diabetes Obes | Metabolic complications of obesity in childhood and adolescence: more than just diabetes. | 2008 | Details |
| A52995 | 18164296 | Gastroenterology | Insulin resistance in chronic hepatitis C: association with genotypes 1 and 4, serum HCV RNA level, and liver fibrosis. | 2007 | Details |
| A52997 | 18154189 | Clin Cornerstone | Metabolic consequences of hyperglycemia and insulin resistance. | 2007 | Details |
| A53001 | 17933490 | Genomics | Gene expression profiling in livers of mice after acute inhibition of beta-oxidation. | 2007 | Details |
| A53002 | 17925761 | Gastroenterol Clin Biol | [Steatosis during chronic hepatitis C: the role of insulin resistance and viral factors]. | 2008 | Details |
| A53003 | 17785696 | Eur J Endocrinol | Fat distribution and storage: how much, where, and how? | 2007 | Details |
| A53005 | 17901224 | Endocrinology | Obesity-induced inflammation in white adipose tissue is attenuated by loss of melanocortin-3 receptor signaling. | 2007 | Details |
| A53006 | 17855068 | J Nutr Biochem | Oxidative stress-induced risk factors associated with the metabolic syndrome: a unifying hypothesis. | 2007 | Details |
| A53007 | 17721396 | J Acquir Immune Defic Syndr | Magnetic resonance spectroscopy of hepatic lipid content and associated risk factors in HIV infection. | 2007 | Details |
| A53008 | 17664243 | Diabetes | FGFR4 prevents hyperlipidemia and insulin resistance but underlies high-fat diet induced fatty liver. | 2007 | Details |
| A53009 | 17611153 | Heart Lung Circ | The clinical biochemistry of obesity-more than skin deep. | 2007 | Details |
| A53015 | 17400720 | Am J Physiol Heart Circ Physiol | Impairment of cardiac insulin signaling and myocardial contractile performance in high-cholesterol/fructose-fed rats. | 2007 | Details |
| A53017 | 17320517 | Am J Med | Effect of insulin resistance, dyslipidemia, and intra-abdominal adiposity on the development of cardiovascular disease and diabetes mellitus. | 2007 | Details |
| A53018 | 17296343 | Am J Med | Abdominal obesity: role in the pathophysiology of metabolic disease and cardiovascular risk. | 2007 | Details |
| A53021 | 17259477 | Diabetes Care | High circulating retinol-binding protein 4 is associated with elevated liver fat but not with total, subcutaneous, visceral, or intramyocellular fat in humans. | 2007 | Details |
| A53024 | 17164113 | Clin Liver Dis | The changing epidemiology and natural history of hepatitis C virus infection. | 2006 | Details |
| A53025 | 17122751 | Panminerva Med | Metabolic syndrome and renal failure: similarities and differences. | 2006 | Details |
| A53026 | 17111296 | Horm Metab Res | Macroangiopathy in adults and children with diabetes: from molecular mechanisms to vascular damage (part 1). | 2006 | Details |
| A53027 | 17106922 | World J Gastroenterol | Mechanisms and significance of liver steatosis in hepatitis C virus infection. | 2006 | Details |
| A53028 | 17077342 | Am J Physiol Endocrinol Metab | Glucocorticoids produce whole body insulin resistance with changes in cardiac metabolism. | 2006 | Details |
| A53029 | 17016629 | Int J Mol Med | Hemostasis alterations in metabolic syndrome (review). | 2006 | Details |
| A53032 | 16956601 | Clin Chim Acta | Molecular mechanisms of insulin resistance and associated diseases. | 2006 | Details |
| A53034 | 16903166 | Clin Cornerstone | Atherogenic dyslipidemia associated with metabolic syndrome and insulin resistance. | 2006 | Details |
| A53035 | 16877964 | J Hypertens | Irbesartan restores the in-vivo insulin signaling pathway leading to Akt activation in obese Zucker rats. | 2006 | Details |
| A53036 | 16778573 | Curr Opin Clin Nutr Metab Care | Metabolic consequences of lipodystrophy in mouse models. | 2006 | Details |
| A53039 | 16750656 | Vascul Pharmacol | Adverse hepatic and cardiac responses to rosiglitazone in a new mouse model of type 2 diabetes: relation to dysregulated phosphatidylcholine metabolism. | 2006 | Details |
| A53044 | 16598526 | Clin Res Cardiol | Gender differences in the metabolic syndrome and their role for cardiovascular disease. | 2006 | Details |
| A53046 | 16557184 | Minerva Gastroenterol Dietol | Steatosis, insulin resistance and fibrosis progression in chronic hepatitis C. | 2006 | Details |
| A53047 | 16516330 | J Hepatol | Gallbladder disease is associated with insulin resistance in a high risk Hispanic population. | 2006 | Details |
| A53049 | 16478779 | Am J Physiol Endocrinol Metab | Elevated resistin levels in cirrhosis are associated with the proinflammatory state and altered hepatic glucose metabolism but not with insulin resistance. | 2006 | Details |
| A53050 | 16477380 | Mol Cell Biochem | Peroxisome proliferator-activated receptor-alpha selective ligand reduces adiposity, improves insulin sensitivity and inhibits atherosclerosis in LDL receptor-deficient mice. | 2006 | Details |
| A53056 | 16253642 | Metabolism | Endothelin antagonism improves hepatic insulin sensitivity associated with insulin signaling in Zucker fatty rats. | 2005 | Details |
| A53057 | 16248830 | Curr Drug Targets Cardiovasc Haematol Disord | Role of PPAR- gamma agonist thiazolidinediones in treatment of pre-diabetic and diabetic individuals: a cardiovascular perspective. | 2005 | Details |
| A53058 | 16225474 | Aliment Pharmacol Ther | Review article: hepatitis C virus-associated steatosis--pathogenic mechanisms and clinical implications. | 2005 | Details |
| A53060 | 16183630 | Am J Physiol Regul Integr Comp Physiol | Tesaglitazar, a dual PPAR{alpha}/{gamma} agonist, ameliorates glucose and lipid intolerance in obese Zucker rats. | 2005 | Details |
| A53061 | 16170675 | Herz | [Metabolic syndrome and hyperlipidemia in HIV-positive patients]. | 2005 | Details |
| A53064 | 16088969 | Diabetes Metab Res Rev | Prevention of nutritionally induced diabetes by rosiglitazone in the gerbil Psammomys obesus. | 2006 | Details |
| A53067 | 15817811 | Am J Physiol Gastrointest Liver Physiol | Acute hepatic steatosis in mice by blocking beta-oxidation does not reduce insulin sensitivity of very-low-density lipoprotein production. | 2005 | Details |
| A53068 | 15809359 | Hypertension | A new transgenic rat model of hepatic steatosis and the metabolic syndrome. | 2005 | Details |
| A53072 | 15687414 | Obes Res | Pathophysiology and long-term management of the metabolic syndrome. | 2004 | Details |
| A53073 | 15672115 | Int J Obes (Lond) | Childhood obesity and insulin resistance in a Yucatan mini-piglet model: putative roles of IGF-1 and muscle PPARs in adipose tissue activity and development. | 2005 | Details |
| A53077 | 15553597 | Nutr Metab Cardiovasc Dis | Insulin sensitivity and hepatic steatosis in obese subjects with normal glucose tolerance. | 2004 | Details |
| A53084 | 15297448 | Endocrinology | Small-molecule insulin mimetic reduces hyperglycemia and obesity in a nongenetic mouse model of type 2 diabetes. | 2004 | Details |
| A53085 | 15262452 | Clin Ther | A comparison of the effects of thiazolidinediones and metformin on metabolic control in patients with type 2 diabetes mellitus. | 2004 | Details |
| A53087 | 15181027 | J Clin Endocrinol Metab | Medical consequences of obesity. | 2004 | Details |
| A53088 | 15173878 | J Clin Invest | The case of visceral fat: argument for the defense. | 2004 | Details |
| A53089 | 15166810 | Curr Opin Lipidol | Pathophysiology of dyslipidemia and increased cardiovascular risk in HIV lipodystrophy: a model of 'systemic steatosis'. | 2004 | Details |
| A53091 | 15090211 | Assay Drug Dev Technol | A self-contained 48-well fatty acid oxidation assay. | 2004 | Details |
| A53098 | 14739074 | Biochimie | Central role of the adipocyte in the insulin-sensitising and cardiovascular risk modifying actions of the thiazolidinediones. | 2003 | Details |
| A53099 | 14728015 | Am J Cardiovasc Drugs | Drug treatment of combined hyperlipidemia. | 2001 | Details |
| A53100 | 14717339 | Hypertens Res | Effects of radiation on fatty liver and metabolic coronary risk factors among atomic bomb survivors in Nagasaki. | 2003 | Details |
| A53107 | 12930161 | Drugs | Metformin: new understandings, new uses. | 2003 | Details |
| A53110 | 12793594 | Int J Clin Pract Suppl | The relationship of obesity to the metabolic syndrome. | 2003 | Details |
| A53114 | 12660870 | Horm Metab Res | Depot-specific hormonal characteristics of subcutaneous and visceral adipose tissue and their relation to the metabolic syndrome. | 2003 | Details |
| A53118 | 12401884 | J Lipid Res | AZ 242, a novel PPARalpha/gamma agonist with beneficial effects on insulin resistance and carbohydrate and lipid metabolism in ob/ob mice and obese Zucker rats. | 2002 | Details |
| A53122 | 12015640 | Klin Padiatr | [Lipodystrophies]. | 2002 | Details |
| A53123 | 11921433 | Diabetes Metab Res Rev | The mode of action of thiazolidinediones. | 2002 | Details |
| A53124 | 11921432 | Diabetes Metab Res Rev | Insulin resistance in type 2 diabetes: role of fatty acids. | 2002 | Details |
| A53126 | 11832699 | J Acquir Immune Defic Syndr | Long-term exposure to lifelong therapies. | 2002 | Details |
| A53129 | 11712670 | Life Sci | Can associations between free fatty acid levels and metabolic parameters determine insulin resistance development in obese Zucker rats? | 2001 | Details |
| A53137 | 10889795 | Br J Nutr | Visceral fat and insulin resistance--causative or correlative? | 2000 | Details |
| A53139 | 10842668 | Ann N Y Acad Sci | Molecular pathology in the obese spontaneous hypertensive Koletsky rat: a model of syndrome X. | 1999 | Details |
| A53144 | 10499142 | Cent Eur J Public Health | Ischaemic heart disease as an effect of obesity-related metabolic disturbances. | 1999 | Details |
| A53147 | 10321453 | Blood Press Suppl | Anti-hyperglycemic activity of moxonidine: metabolic and molecular effects in obese spontaneously hypertensive rats. | 1998 | Details |
| A53159 | 9243107 | Diabetologia | Short-term oestrogen replacement therapy improves insulin resistance, lipids and fibrinolysis in postmenopausal women with NIDDM. | 1997 | Details |
| A53160 | 9076669 | Lipids | Non-insulin dependent diabetes mellitus in Psammomys obesus is independent of changes in tissue fatty acid composition. | 1997 | Details |
| A53161 | 9288540 | Exp Clin Endocrinol Diabetes | The role of insulin and proinsulin in the regulation of triglyceride metabolism. | 1997 | Details |
| A53162 | 8963349 | Int J Obes Relat Metab Disord | The influence of fatty liver on insulin clearance and insulin resistance in non-diabetic Japanese subjects. | 1995 | Details |
| A53164 | 7523453 | J Clin Invest | Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha. | 1994 | Details |
| A53167 | 8394500 | Med Hypotheses | Metabolic disorders of cattle. | 1993 | Details |
| A53168 | 8262497 | Horm Res | Endocrine-metabolic pattern and adipose tissue distribution. | 1993 | Details |
| A53172 | 1773700 | Diabetes Care | Metabolic implications of body fat distribution. | 1991 | Details |