Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Fructose1035 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A22546 | 24475018 | PLoS One | Lactobacillus rhamnosus GG protects against non-alcoholic fatty liver disease in mice. | 2014 | Details |
| A22584 | 24445047 | J Nutr Biochem | Role of immunodeficient animal models in the development of fructose induced NAFLD. | 2013 | Details |
| A22707 | 24366230 | Curr Opin Lipidol | Nutrition, nonalcoholic fatty liver disease and the microbiome: recent progress in the field. | 2014 | Details |
| A22715 | 24361606 | Biochim Biophys Acta | Lipoic acid prevents fructose-induced changes in liver carbohydrate metabolism: role of oxidative stress. | 2013 | Details |
| A22738 | 24345826 | J Pediatr Gastroenterol Nutr | Lower fructose intake may help protect against development of nonalcoholic fatty liver in adolescents with obesity. | 2014 | Details |
| A22767 | 24321741 | Eur J Med Res | Dietary fructose enhances the incidence of precancerous hepatocytes induced by administration of diethylnitrosamine in rat. | 2013 | Details |
| A22770 | 24321090 | BMC Gastroenterol | Role of serotonin in fatty acid-induced non-alcoholic fatty liver disease in mice. | 2013 | Details |
| A22783 | 24307947 | J Lipids | Grape seed proanthocyanidin rescues rats from steatosis: a comparative and combination study with metformin. | 2013 | Details |
| A22853 | 24251710 | J Gastroenterol Hepatol | Role of diet and nutritional management in non-alcoholic fatty liver disease. | 2013 | Details |
| A22933 | 24196354 | Int J Mol Sci | Hepatic adverse effects of fructose consumption independent of overweight/obesity. | 2013 | Details |
| A22983 | 24134913 | Biochem Pharmacol | Morin reduces hepatic inflammation-associated lipid accumulation in high fructose-fed rats via inhibiting sphingosine kinase 1/sphingosine 1-phosphate signaling pathway. | 2013 | Details |
| A22996 | 24129399 | Am J Physiol Endocrinol Metab | Eplerenone ameliorates the phenotypes of metabolic syndrome with NASH in liver-specific SREBP-1c Tg mice fed high-fat and high-fructose diet. | 2013 | Details |
| A23093 | 24045866 | Am J Physiol Endocrinol Metab | The rate of production of uric acid by hepatocytes is a sensitive index of compromised cell ATP homeostasis. | 2013 | Details |
| A23094 | 24044579 | Lipids Health Dis | Age-dependent effect of high-fructose and high-fat diets on lipid metabolism and lipid accumulation in liver and kidney of rats. | 2013 | Details |
| A23096 | 24042997 | Int J Mol Med | The chemical chaperon 4-phenylbutyric acid ameliorates hepatic steatosis through inhibition of de novo lipogenesis in high-fructose-fed rats. | 2013 | Details |
| A23111 | 24033459 | Clin Exp Pharmacol Physiol | Fructose, pregnancy and later life impacts. | 2013 | Details |
| A23187 | 23976771 | JPEN J Parenter Enteral Nutr | The effect of a low fructose and low glycemic index/load (FRAGILE) dietary intervention on indices of liver function, cardiometabolic risk factors, and body composition in children and adolescents with nonalcoholic fatty liver disease (NAFLD). | 2013 | Details |
| A23236 | 23933265 | J Hepatol | Industrial, not fruit fructose intake is associated with the severity of liver fibrosis in genotype 1 chronic hepatitis C patients. | 2013 | Details |
| A23288 | 23896654 | Nutrients | Dietary omega-3 fatty acid deficiency and high fructose intake in the development of metabolic syndrome, brain metabolic abnormalities, and non-alcoholic fatty liver disease. | 2013 | Details |
| A23292 | 23894677 | PLoS One | Vismodegib suppresses TRAIL-mediated liver injury in a mouse model of nonalcoholic steatohepatitis. | 2013 | Details |
| A23298 | 23886860 | Am J Physiol Gastrointest Liver Physiol | Diet-induced mouse model of fatty liver disease and nonalcoholic steatohepatitis reflecting clinical disease progression and methods of assessment. | 2013 | Details |
| A23321 | 23872500 | Gastroenterology | No difference between high-fructose and high-glucose diets on liver triacylglycerol or biochemistry in healthy overweight men. | 2013 | Details |
| A23331 | 23866299 | Fibrogenesis Tissue Repair | Non-alcoholic fatty liver disease (NAFLD): a tale of fat and sugar? | 2013 | Details |
| A23394 | 23819696 | Clin Exp Pharmacol Physiol | Supplementation of the maternal diet during pregnancy with chocolate and fructose interacts with the high-fat diet of the young to facilitate the onset of metabolic disorders in rat offspring. | 2013 | Details |
| A23427 | 23793849 | Curr Hypertens Rep | Fructose-containing sugars, blood pressure, and cardiometabolic risk: a critical review. | 2013 | Details |
| A23431 | 23791610 | Eur J Pharmacol | Oxymatrine attenuates hepatic steatosis in non-alcoholic fatty liver disease rats fed with high fructose diet through inhibition of sterol regulatory element binding transcription factor 1 (Srebf1) and activation of peroxisome proliferator activated receptor alpha (Pparα). | 2013 | Details |
| A23449 | 23770462 | Mol Cell Endocrinol | Hepatic energy metabolism in human diabetes mellitus, obesity and non-alcoholic fatty liver disease. | 2013 | Details |
| A23465 | 23756665 | Korean J Gastroenterol | [The role of diet in non-alcoholic fatty liver disease]. | 2013 | Details |
| A23467 | 23754536 | Mol Med Rep | Oxymatrine ameliorates non-alcoholic fatty liver disease in rats through peroxisome proliferator-activated receptor-α activation. | 2013 | Details |
| A23511 | 25755484 | J Clin Exp Hepatol | The future liver of the Asia pacific: fatter and firmer from more fructose and fortune? | 2012 | Details |
| A23519 | 23715726 | Am J Physiol Endocrinol Metab | Ezetimibe prevents hepatic steatosis induced by a high-fat but not a high-fructose diet. | 2013 | Details |
| A23583 | 23657151 | Curr Opin Clin Nutr Metab Care | Carbohydrate intake and nonalcoholic fatty liver disease. | 2013 | Details |
| A23590 | 23653231 | Mol Nutr Food Res | Effects of raftilose on serum biochemistry and liver morphology in rats fed with normal or high-fat diet. | 2013 | Details |
| A23615 | 23625798 | Pediatr Obes | Calorie-sweetened beverages and fructose: what have we learned 10 years later. | 2013 | Details |
| A23674 | 23576902 | ScientificWorldJournal | Current concepts and management approaches in nonalcoholic fatty liver disease. | 2013 | Details |
| A23726 | 23531105 | Lipids Health Dis | Rosiglitazone and bezafibrate modulate gene expression in a rat model of non-alcoholic fatty liver disease--a historical prospective. | 2013 | Details |
| A23776 | 23489555 | Basic Clin Pharmacol Toxicol | Effects of antihypertensive and triglyceride lowering agents on splenocyte apoptosis in rats with fatty liver. | 2013 | Details |
| A23778 | 23488792 | J Gastroenterol Hepatol | Antigen peptide transporter 1 is involved in the development of fructose-induced hepatic steatosis in mice. | 2013 | Details |
| A23786 | 23482247 | World J Gastroenterol | Fructose as a key player in the development of fatty liver disease. | 2013 | Details |
| A23795 | 23477499 | Antioxid Redox Signal | Peroxiredoxin 4 protects against nonalcoholic steatohepatitis and type 2 diabetes in a nongenetic mouse model. | 2013 | Details |
| A23918 | 23390127 | Hepatology | Dietary fructose in nonalcoholic fatty liver disease. | 2013 | Details |
| A24043 | 23286927 | Nutr Clin Pract | Nonalcoholic fatty liver disease and the metabolic syndrome: clinical implications and treatment. | 2013 | Details |
| A24047 | 23283181 | Curr Opin Gastroenterol | Dietary treatment of nonalcoholic steatohepatitis. | 2013 | Details |
| A24091 | 23236229 | World J Gastroenterol | Way back for fructose and liver metabolism: bench side to molecular insights. | 2012 | Details |
| A24197 | 23129794 | J Physiol | The role of fructose transporters in diseases linked to excessive fructose intake. | 2012 | Details |
| A24383 | 22952059 | Mol Med | Female mice are more susceptible to nonalcoholic fatty liver disease: sex-specific regulation of the hepatic AMP-activated protein kinase-plasminogen activator inhibitor 1 cascade, but not the hepatic endotoxin response. | 2012 | Details |
| A24388 | 22949106 | Curr Atheroscler Rep | Fructose and risk of cardiometabolic disease. | 2012 | Details |
| A24454 | 22878240 | Curr Opin Clin Nutr Metab Care | Improving dietary patterns in patients with nonalcoholic fatty liver disease. | 2012 | Details |
| A24469 | 22864348 | Yakugaku Zasshi | [Retinoids as promising treatment for non-alcoholic fatty liver disease]. | 2012 | Details |
| A24479 | 22854109 | Metabolism | High-fat, high-fructose diet induces hepatic iron overload via a hepcidin-independent mechanism prior to the onset of liver steatosis and insulin resistance in mice. | 2012 | Details |
| A24534 | 22796155 | J Hepatol | Phenotyping the effect of diet on non-alcoholic fatty liver disease. | 2012 | Details |
| A24535 | 22795319 | Clin Res Hepatol Gastroenterol | Does fructose consumption contribute to non-alcoholic fatty liver disease? | 2012 | Details |
| A24561 | 22749137 | J Nutr Biochem | Lactobacillus casei Shirota protects from fructose-induced liver steatosis: a mouse model. | 2012 | Details |
| A24595 | 22713601 | Lipids Health Dis | Fructose-rich diet leads to reduced aerobic capacity and to liver injury in rats. | 2012 | Details |
| A24605 | 22700625 | Ann Hepatol |  Gut microbiota and nonalcoholic fatty liver disease. | 2012 | Details |
| A24607 | 22698815 | Toxicol Lett | Endoplasmic reticulum stress is involved in hepatic SREBP-1c activation and lipid accumulation in fructose-fed mice. | 2012 | Details |
| A24646 | 22652776 | Front Biosci (Landmark Ed) | Dietary approach in the prevention and treatment of NAFLD. | 2012 | Details |
| A24728 | 22554494 | Brain Behav Immun | Exercise training attenuates hepatic inflammation, fibrosis and macrophage infiltration during diet induced-obesity in mice. | 2012 | Details |
| A24743 | 22544914 | J Clin Endocrinol Metab | Children with NAFLD are more sensitive to the adverse metabolic effects of fructose beverages than children without NAFLD. | 2012 | Details |
| A24745 | 22543623 | Eur J Nutr | A moderate weight reduction through dietary intervention decreases hepatic fat content in patients with non-alcoholic fatty liver disease (NAFLD): a pilot study. | 2012 | Details |
| A24753 | 22535755 | J Nutr | Quercetin ameliorates cardiovascular, hepatic, and metabolic changes in diet-induced metabolic syndrome in rats. | 2012 | Details |
| A24758 | 22531980 | Hepatology | Retinoids ameliorate insulin resistance in a leptin-dependent manner in mice. | 2012 | Details |
| A24764 | 22525431 | Lab Invest | Metformin protects against the development of fructose-induced steatosis in mice: role of the intestinal barrier function. | 2012 | Details |
| A24808 | 22469640 | J Clin Gastroenterol | The role of nutrients in the development, progression, and treatment of nonalcoholic fatty liver disease. | 2012 | Details |
| A24810 | 22469071 | Aliment Pharmacol Ther | Review article: fructose in non-alcoholic fatty liver disease. | 2012 | Details |
| A24819 | 22467259 | Hepatology | Higher dietary fructose is associated with impaired hepatic adenosine triphosphate homeostasis in obese individuals with type 2 diabetes. | 2012 | Details |
| A24901 | 22378327 | J Nutr | Coffee extract attenuates changes in cardiovascular and hepatic structure and function without decreasing obesity in high-carbohydrate, high-fat diet-fed male rats. | 2012 | Details |
| A24982 | 22280920 | Physiol Behav | Non-alcoholic fatty liver disease impairs hippocampal-dependent memory in male rats. | 2012 | Details |
| A25069 | 22197855 | J Pediatr Gastroenterol Nutr | Correlation of vitamin E, uric acid, and diet composition with histologic features of pediatric NAFLD. | 2012 | Details |
| A25155 | 22129639 | J Nutr Biochem | The role of fructose-enriched diets in mechanisms of nonalcoholic fatty liver disease. | 2011 | Details |
| A25255 | 22030814 | Acta Cir Bras | Fructose and NAFLD: metabolic implications and models of induction in rats. | 2011 | Details |
| A25273 | 22018861 | Br J Nutr | Toll-like receptors 1-9 are elevated in livers with fructose-induced hepatic steatosis. | 2011 | Details |
| A25287 | 21994008 | Hepatology | Vitamin D deficiency in obese rats exacerbates nonalcoholic fatty liver disease and increases hepatic resistin and Toll-like receptor activation. | 2012 | Details |
| A25321 | 21957486 | PLoS One | GLP-1 analogs reduce hepatocyte steatosis and improve survival by enhancing the unfolded protein response and promoting macroautophagy. | 2011 | Details |
| A25417 | 21876630 | World J Gastroenterol | Nutrition and physical activity in NAFLD: an overview of the epidemiological evidence. | 2011 | Details |
| A25420 | 21875310 | Crit Rev Clin Lab Sci | Non-alcoholic fatty liver disease. | 2011 | Details |
| A25443 | 21836057 | Am J Physiol Gastrointest Liver Physiol | Fast food diet mouse: novel small animal model of NASH with ballooning, progressive fibrosis, and high physiological fidelity to the human condition. | 2011 | Details |
| A25482 | 21781943 | J Hepatol | High fructose feeding induces copper deficiency in Sprague-Dawley rats: a novel mechanism for obesity related fatty liver. | 2011 | Details |
| A25720 | 21508207 | J Nutr | Rutin attenuates metabolic changes, nonalcoholic steatohepatitis, and cardiovascular remodeling in high-carbohydrate, high-fat diet-fed rats. | 2011 | Details |
| A25764 | 21476914 | Expert Rev Gastroenterol Hepatol | Inflammation in nonalcoholic steatohepatitis. | 2011 | Details |
| A25981 | 21240032 | Pancreas | Effect of different obesogenic diets on pancreatic histology in Ossabaw miniature swine. | 2011 | Details |
| A26090 | 21122807 | Toxicol Appl Pharmacol | Reduction of liver fructokinase expression and improved hepatic inflammation and metabolism in liquid fructose-fed rats after atorvastatin treatment. | 2010 | Details |
| A26121 | 21067942 | Trends Endocrinol Metab | Fructose induced lipogenesis: from sugar to fat to insulin resistance. | 2010 | Details |
| A26174 | 20956972 | Lab Invest | Mirnome analysis reveals novel molecular determinants in the pathogenesis of diet-induced nonalcoholic fatty liver disease. | 2010 | Details |
| A26180 | 20946638 | Lipids Health Dis | Exercise counteracts fatty liver disease in rats fed on fructose-rich diet. | 2010 | Details |
| A26199 | 20923528 | J Diabetes | Genistein improves liver function and attenuates non-alcoholic fatty liver disease in a rat model of insulin resistance. | 2009 | Details |
| A26240 | 20847296 | J Lipid Res | Protective effect of bile acids on the onset of fructose-induced hepatic steatosis in mice. | 2010 | Details |
| A26249 | 20842026 | Curr Opin Clin Nutr Metab Care | Nutritional modulation of nonalcoholic fatty liver disease and insulin resistance: human data. | 2010 | Details |
| A26276 | 20801629 | J Nutr Biochem | Role of tumor necrosis factor α (TNFα) in the onset of fructose-induced nonalcoholic fatty liver disease in mice. | 2010 | Details |
| A26310 | 20664312 | Korean J Gastroenterol | [Nonalcoholic fatty liver disease]. | 2010 | Details |
| A26322 | 20651844 | Biochem Cell Biol | Calorie restriction on insulin resistance and expression of SIRT1 and SIRT4 in rats. | 2010 | Details |
| A26400 | 20518077 | World J Gastroenterol | Soft drinks consumption and nonalcoholic fatty liver disease. | 2010 | Details |
| A26525 | 20368739 | Nat Rev Gastroenterol Hepatol | The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome. | 2010 | Details |
| A26539 | 20301112 | Hepatology | Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease. | 2010 | Details |
| A26553 | 20216561 | Eur J Clin Nutr | Dietary and physical activity patterns in children with fatty liver. | 2010 | Details |
| A26556 | 20210788 | Basic Clin Pharmacol Toxicol | Hepatic effects of rosiglitazone in rats with the metabolic syndrome. | 2010 | Details |
| A26603 | 20111022 | Obesity (Silver Spring) | Effect of dietary monosodium glutamate on HFCS-induced hepatic steatosis: expression profiles in the liver and visceral fat. | 2010 | Details |
| A26625 | 20078219 | Annu Rev Pathol | Nonalcoholic fatty liver disease: pathology and pathogenesis. | 2010 | Details |
| A26673 | 20010099 | Curr Opin Gastroenterol | Implications of diet on nonalcoholic fatty liver disease. | 2010 | Details |
| A26822 | 19713474 | Am J Physiol Gastrointest Liver Physiol | Serotonin reuptake transporter (SERT) plays a critical role in the onset of fructose-induced hepatic steatosis in mice. | 2009 | Details |