Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A03753 | 33877366 | Diabetologia | Liver-targeting drugs and their effect on blood glucose and hepatic lipids. | 2021 | Details |
| A03755 | 33876811 | Food Funct | The role of iron homeostasis in adipocyte metabolism. | 2021 | Details |
| A03758 | 33872860 | Mol Metab | Iron aggravates hepatic insulin resistance in the absence of inflammation in a novel db/db mouse model with iron overload. | 2021 | Details |
| A03765 | 33871240 | J Sports Med Phys Fitness | The effect of combined exercises on the plasma levels of retinol-binding protein 4 and its relationship with insulin resistance and hepatic fat content in postmenopausal women with nonalcoholic fatty liver disease. | 2021 | Details |
| A03771 | 33869077 | Front Cell Infect Microbiol | The Role of Gut Microbiota in Duodenal-Jejunal Bypass Surgery-Induced Improvement of Hepatic Steatosis in HFD-Fed Rats. | 2021 | Details |
| A03776 | 33867442 | Eur J Gastroenterol Hepatol | Small intestinal bacterial overgrowth and orocecal transit time in patients of nonalcoholic fatty liver disease. | 2021 | Details |
| A03782 | 33865898 | Metabolism | Collagen β(1-O) galactosyltransferase 2 deficiency contributes to lipodystrophy and aggravates NAFLD related to HMW adiponectin in mice. | 2021 | Details |
| A03785 | 33864798 | Metabolism | Non-alcoholic fatty liver disease, insulin resistance, metabolic syndrome and their association with vascular risk. | 2021 | Details |
| A03789 | 33862461 | Biochem Biophys Res Commun | Canagliflozin ameliorates hepatic fat deposition in obese diabetic mice: Role of prostaglandin E2. | 2021 | Details |
| A03794 | 33862045 | Metabolism | Determinants of hepatic insulin clearance - Results from a Mendelian Randomization study. | 2021 | Details |
| A03796 | 33861449 | Adv Exp Med Biol | Beneficial Effects of Plant-Derived Natural Products on Non-alcoholic Fatty Liver Disease. | 2021 | Details |
| A03797 | 33861444 | Adv Exp Med Biol | Medicinal Plants and Phytochemicals Regulating Insulin Resistance and Glucose Homeostasis in Type 2 Diabetic Patients: A Clinical Review. | 2021 | Details |
| A03798 | 33861434 | Adv Exp Med Biol | The Effect of Curcumin Phytosome on the Treatment of Patients with Non-alcoholic Fatty Liver Disease: A Double-Blind, Randomized, Placebo-Controlled Trial. | 2021 | Details |
| A03800 | 33860630 | FEBS J | Liver macrophages and inflammation in physiology and physiopathology of non-alcoholic fatty liver disease. | 2021 | Details |
| A03803 | 33860199 | ACS Pharmacol Transl Sci | Peripherally Selective CB1 Receptor Antagonist Improves Symptoms of Metabolic Syndrome in Mice. | 2021 | Details |
| A03804 | 33860188 | ACS Pharmacol Transl Sci | Pyruvate Dehydrogenase as a Therapeutic Target for Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03807 | 33860117 | Hepatol Commun | Lipoprotein Insulin Resistance Index Reflects Liver Fat Content in Patients With Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A03811 | 33860093 | JGH Open | Non-alcoholic fatty liver disease in premenopausal women with polycystic ovary syndrome: A systematic review and meta-analysis. | 2021 | Details |
| A03815 | 33859314 | Sci Rep | Extra virgin olive oil improved body weight and insulin sensitivity in high fat diet-induced obese LDLr-/-.Leiden mice without attenuation of steatohepatitis. | 2021 | Details |
| A03819 | 33857552 | Adv Drug Deliv Rev | Cellular protein markers, therapeutics, and drug delivery strategies in the treatment of diabetes-associated liver fibrosis. | 2021 | Details |
| A03829 | 33855386 | Minerva Endocrinol (Torino) | Relationship between plasma 12,13-diHOME level and nonalcoholic fatty liver disease in patients with type 2 diabetes and obesity. | 2021 | Details |
| A03837 | 33852720 | Clin Infect Dis | Growth Hormone Releasing Hormone Reduces Circulating Markers of Immune Activation in Parallel with Effects on Hepatic Immune Pathways in Individuals with HIV-infection and Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03842 | 33851592 | Wiad Lek | THE ROLE OF ZONULIN IN THE DEVELOPMENT OF LIVER FIBROSIS IN OBESE ADOLESCENTS. | 2021 | Details |
| A03856 | 33844769 | Rev Med Chil | [The impact on metabolic and reproductive diseases of low-carbohydrate and ketogenic diets]. | 2020 | Details |
| A03860 | 33841814 | Food Sci Nutr | Functional beverages improve insulin resistance and hepatic steatosis modulating lysophospholipids in diet-induced obese rats. | 2021 | Details |
| A03864 | 33840072 | Curr Obes Rep | The Role of Mitochondrial Adaptation and Metabolic Flexibility in the Pathophysiology of Obesity and Insulin Resistance: an Updated Overview. | 2021 | Details |
| A03865 | 33839905 | Eur J Nutr | Improving insulin sensitivity, liver steatosis and fibrosis in type 2 diabetes by a food-based digital education-assisted lifestyle intervention program: a feasibility study. | 2021 | Details |
| A03869 | 33838673 | Nutr J | Effects of supplementation with main coffee components including caffeine and/or chlorogenic acid on hepatic, metabolic, and inflammatory indices in patients with non-alcoholic fatty liver disease and type 2 diabetes: a randomized, double-blind, placebo-controlled, clinical trial. | 2021 | Details |
| A03874 | 33837670 | Liver Transpl | Atherogenic Dyslipidemia After Liver Transplantation: Mechanisms and Clinical Implications. | 2021 | Details |
| A03881 | 33833974 | Pediatr Gastroenterol Hepatol Nutr | Vitamin D Effect on Ultrasonography and Laboratory Indices and Biochemical Indicators in the Blood: an Interventional Study on 12 to 18-Year-Old Children with Fatty Liver. | 2021 | Details |
| A03891 | 33831691 | Phytomedicine | Therapeutic effect of oxyberberine on obese non-alcoholic fatty liver disease rats. | 2021 | Details |
| A03892 | 33831474 | Adv Drug Deliv Rev | Lipid based nanocarriers for effective drug delivery and treatment of diabetes associated liver fibrosis. | 2021 | Details |
| A03893 | 33830112 | Mymensingh Med J | Study on Alanine Aminotransferase in Patients of Type 2 Diabetes Mellitus. | 2021 | Details |
| A03908 | 33823088 | J Pediatr Endocrinol Metab | Early menarche is associated with insulin-resistance and non-alcoholic fatty liver disease in adolescents with obesity. | 2021 | Details |
| A03910 | 33822497 | Int J Med Mushrooms | Bioactive Components and Possible Activities of Medicinal Mushrooms in Alleviating the Pathogenesis of Nonalcoholic Fatty Liver Disease (Review). | 2021 | Details |
| A03912 | 33822104 | J Pharm Pharmacol | Eugenol modulates insulin sensitivity by upregulating insulin receptor substrate-2 in non-alcoholic fatty liver disease in rats. | 2021 | Details |
| A03914 | 33820884 | Gut Liver | Effects of Metformin on Hepatic Steatosis in Adults with Nonalcoholic Fatty Liver Disease and Diabetes: Insights from the Cellular to Patient Levels. | 2021 | Details |
| A03915 | 33820503 | Mini Rev Med Chem | Mechanism of Natural Drugs on Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03918 | 33818349 | Nutr Res Rev | Effects of betaine on non-alcoholic liver disease. | 2021 | Details |
| A03935 | 33813276 | Biochem Biophys Res Commun | Hepatocytes derived increased SAA1 promotes intrahepatic platelet aggregation and aggravates liver inflammation in NAFLD. | 2021 | Details |
| A03939 | 33811619 | Eat Weight Disord | Association of obstructive sleep apnea with non-alcoholic fatty liver disease in patients with obesity: an observational study. | 2021 | Details |
| A03942 | 33811367 | Hepatology | Saroglitazar, a PPAR-α/γ Agonist, for Treatment of NAFLD: A Randomized Controlled Double-Blind Phase 2 Trial. | 2021 | Details |
| A03947 | 33810566 | Int J Mol Sci | Hepatic Senescence Accompanies the Development of NAFLD in Non-Aged Mice Independently of Obesity. | 2021 | Details |
| A03952 | 33809593 | Nutrients | Fortifying Butterfat with Soybean Oil Attenuates the Onset of Diet-Induced Non-Alcoholic Steatohepatitis and Glucose Intolerance. | 2021 | Details |
| A03953 | 33809062 | Mar Drugs | Fucoidan and Fucoxanthin Attenuate Hepatic Steatosis and Inflammation of NAFLD through Modulation of Leptin/Adiponectin Axis. | 2021 | Details |
| A03958 | 33808007 | Int J Mol Sci | Momordica cochinchinensis Aril Ameliorates Diet-Induced Metabolic Dysfunction and Non-Alcoholic Fatty Liver by Modulating Gut Microbiota. | 2021 | Details |
| A03963 | 33807573 | Int J Mol Sci | An Overview of the Molecular Mechanisms Contributing to Musculoskeletal Disorders in Chronic Liver Disease: Osteoporosis, Sarcopenia, and Osteoporotic Sarcopenia. | 2021 | Details |
| A03968 | 33806527 | Pharmaceuticals (Basel) | The Evaluation of Drug Delivery Nanocarrier Development and Pharmacological Briefing for Metabolic-Associated Fatty Liver Disease (MAFLD): An Update. | 2021 | Details |
| A03970 | 33805912 | Int J Mol Sci | Potential of Nutraceutical Supplementation in the Modulation of White and Brown Fat Tissues in Obesity-Associated Disorders: Role of Inflammatory Signalling. | 2021 | Details |
| A03977 | 33804296 | J Clin Med | From Nonalcoholic Fatty Liver Disease (NAFLD) to Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD)-New Terminology in Pediatric Patients as a Step in Good Scientific Direction? | 2021 | Details |
| A03983 | 33802047 | J Clin Med | Natural History of NAFLD. | 2021 | Details |
| A03990 | 33800465 | Metabolites | Insulin Resistance across the Spectrum of Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A03993 | 33798787 | Cell Mol Gastroenterol Hepatol | Hypoxia via ERK Signaling Inhibits Hepatic PPARα to Promote Fatty Liver. | 2021 | Details |
| A03999 | 33794784 | BMC Gastroenterol | A randomised placebo controlled trial of VSL#3® probiotic on biomarkers of cardiovascular risk and liver injury in non-alcoholic fatty liver disease. | 2021 | Details |
| A04001 | 33794740 | Adipocyte | Swertiamarin supplementation prevents obesity-related chronic inflammation and insulin resistance in mice fed a high-fat diet. | 2021 | Details |
| A04005 | 33792864 | J Endocrinol Invest | Long non-coding RNAs in metabolic disorders: pathogenetic relevance and potential biomarkers and therapeutic targets. | 2021 | Details |
| A04010 | 33790119 | Yakugaku Zasshi | [VNUT Is a Therapeutic Target for Type 2 Diabetes and NASH]. | 2021 | Details |
| A04013 | 33788613 | Environ Health Perspect | Effect of Epidermal Growth Factor Treatment and Polychlorinated Biphenyl Exposure in a Dietary-Exposure Mouse Model of Steatohepatitis. | 2021 | Details |
| A04016 | 33788377 | Liver Int | Elafibranor and liraglutide improve differentially liver health and metabolism in a mouse model of non-alcoholic steatohepatitis. | 2021 | Details |
| A04025 | 33785339 | Life Sci | A rapid juvenile murine model of nonalcoholic steatohepatitis (NASH): Chronic intermittent hypoxia exacerbates Western diet-induced NASH. | 2021 | Details |
| A04030 | 33783746 | Adv Exp Med Biol | Prevention of NAFLD/NASH by Astaxanthin and β-Cryptoxanthin. | 2021 | Details |
| A04031 | 33783745 | Adv Exp Med Biol | Molecular Mechanisms of Nonalcoholic Fatty Liver Disease (NAFLD)/Nonalcoholic Steatohepatitis (NASH). | 2021 | Details |
| A04032 | 33782980 | Andrologia | Nonalcoholic fatty liver disease and risk of prostatic diseases: Roles of insulin resistance. | 2021 | Details |
| A04034 | 33782517 | Sci Rep | Non-alcoholic fatty liver disease in polycystic ovary syndrome women. | 2021 | Details |
| A04040 | 33779880 | Dig Dis Sci | Progression of Nonalcoholic Fatty Liver Disease-Associated Fibrosis in a Large Cohort of Patients with Type 2 Diabetes. | 2021 | Details |
| A04041 | 33779332 | Hum Exp Toxicol | Therapeutic effects of myocardin-related transcription factor A (MRTF-A) knockout on experimental mice with nonalcoholic steatohepatitis induced by high-fat diet. | 2021 | Details |
| A04045 | 33777674 | Acta Pharm Sin B | S-Allylmercaptocysteine improves alcoholic liver disease partly through a direct modulation of insulin receptor signaling. | 2020 | Details |
| A04050 | 33776471 | Int J Gen Med | The Diabetes Syndrome - A Collection of Conditions with Common, Interrelated Pathophysiologic Mechanisms. | 2021 | Details |
| A04060 | 33773192 | Phytomedicine | Si Miao Formula attenuates non-alcoholic fatty liver disease by modulating hepatic lipid metabolism and gut microbiota. | 2021 | Details |
| A04063 | 33772456 | Indian J Gastroenterol | Efficacy of combining pentoxiphylline and vitamin E versus vitamin E alone in non-alcoholic steatohepatitis- A randomized pilot study. | 2021 | Details |
| A04064 | 33772116 | Commun Biol | INPP4B protects from metabolic syndrome and associated disorders. | 2021 | Details |
| A04067 | 33771728 | Mol Metab | Ube2i deletion in adipocytes causes lipoatrophy in mice. | 2021 | Details |
| A04069 | 33771638 | J Ethnopharmacol | Molecular mechanism of Fufang Zhenzhu Tiaozhi capsule in the treatment of type 2 diabetes mellitus with nonalcoholic fatty liver disease based on network pharmacology and validation in minipigs. | 2021 | Details |
| A04077 | 33768585 | Hepatology | Tumor Necrosis Factor α-Induced Protein 8-Like 2 Alleviates Nonalcoholic Fatty Liver Disease Through Suppressing Transforming Growth Factor Beta-Activated Kinase 1 Activation. | 2021 | Details |
| A04090 | 33763324 | Cureus | Glycogen Hepatopathy: A Reversible yet Relapsing Cause of Hepatitis in Type 1 Diabetics. | 2021 | Details |
| A04100 | 33760189 | Mol Med Rep | Silibinin improves nonalcoholic fatty liver by regulating the expression of miR‑122: An in vitro and in vivo study. | 2021 | Details |
| A04109 | 33754067 | Theranostics | NAD+-boosting therapy alleviates nonalcoholic fatty liver disease via stimulating a novel exerkine Fndc5/irisin. | 2021 | Details |
| A04110 | 33753727 | Cell Death Dis | S-adenosylmethionine upregulates the angiotensin receptor-binding protein ATRAP via the methylation of HuR in NAFLD. | 2021 | Details |
| A04112 | 33753007 | Surg Obes Relat Dis | Duodenal-jejunal bypass maintains hepatic S-adenosylmethionine/S-homocysteine ratio in diet-induced obese rats. | 2021 | Details |
| A04126 | 33746906 | Front Endocrinol (Lausanne) | Ectodysplasin A Is Increased in Non-Alcoholic Fatty Liver Disease, But Is Not Associated With Type 2 Diabetes. | 2021 | Details |
| A04128 | 33746742 | Front Pharmacol | Liraglutide Alleviates Hepatic Steatosis and Liver Injury in T2MD Rats via a GLP-1R Dependent AMPK Pathway. | 2021 | Details |
| A04130 | 33746449 | J Clin Exp Hepatol | What Are the Current Pharmacological Therapies for Nonalcoholic Fatty Liver Disease? | 2020 | Details |
| A04131 | 33746447 | J Clin Exp Hepatol | Study of Cellular Senescence and Vitamin D Deficiency in Nonalcoholic Fatty Liver Disease and The Potential Protective Effect of Vitamin D Supplementation. | 2020 | Details |
| A04134 | 33746082 | J Hepatol | The mitochondrial dicarboxylate carrier prevents hepatic lipotoxicity by inhibiting white adipocyte lipolysis. | 2021 | Details |
| A04141 | 33743554 | Hepatology | Increased Adipose Tissue Fibrogenesis, Not Impaired Expandability, Is Associated With Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A04146 | 33742318 | Curr Diab Rep | The Relationship Between Type 2 Diabetes, NAFLD, and Cardiovascular Risk. | 2021 | Details |
| A04147 | 33741532 | Mol Metab | TCF7 is not essential for glucose homeostasis in mice. | 2021 | Details |
| A04149 | 33740939 | BMC Endocr Disord | Hemoglobin concentration is associated with the incidence of metabolic syndrome. | 2021 | Details |
| A04156 | 33736626 | BMC Endocr Disord | Calcium to magnesium intake ratio and non-alcoholic fatty liver disease development: a case-control study. | 2021 | Details |
| A04157 | 33736456 | Antioxid Redox Signal | Sex Differences in Nonalcoholic Fatty Liver Disease: Estrogen Influence on the Liver-Adipose Tissue Crosstalk. | 2021 | Details |
| A04160 | 33733575 | Biofactors | Quercetin prevents cadmium chloride-induced hepatic steatosis and fibrosis by downregulating the transcription of miR-21. | 2021 | Details |
| A04167 | 33731171 | Nutr Metab (Lond) | Neck circumference as an independent predictor for NAFLD among postmenopausal women with normal body mass index. | 2021 | Details |
| A04173 | 33728708 | Phytother Res | Effect of Nigella sativa in the treatment of nonalcoholic fatty liver disease: A systematic review and meta-analysis of randomized controlled trials. | 2021 | Details |
| A04175 | 33727836 | Diabetes Metab Syndr Obes | Electromagnetic Fields Ameliorate Insulin Resistance and Hepatic Steatosis by Modulating Redox Homeostasis and SREBP-1c Expression in db/db Mice. | 2021 | Details |
| A04176 | 33727658 | Commun Biol | Adiponectin-expressing Treg facilitate T lymphocyte development in thymic nurse cell complexes. | 2021 | Details |
| A04177 | 33727164 | Clin Gastroenterol Hepatol | Effect of Endoscopic Bariatric and Metabolic Therapies on Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis. | 2021 | Details |
| A04189 | 33722690 | Mol Metab | Suppression of insulin-induced gene 1 (INSIG1) function promotes hepatic lipid remodelling and restrains NASH progression. | 2021 | Details |
| A04192 | 33721354 | Clin Exp Pharmacol Physiol | Sodium butyrate ameliorates non-alcoholic fatty liver disease by upregulating miR-150 to suppress CXCR4 expression. | 2021 | Details |
| A04195 | 33720570 | Ter Arkh | [Clinical and prognostic value of metabolic disorders in non-alcoholic fatty liver disease]. | 2020 | Details |
| A04196 | 33720280 | Biochem J | α-Methyl-l-tryptophan as a weight-loss agent in multiple models of obesity in mice. | 2021 | Details |