Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A21880 | 24983336 | Med Sci Sports Exerc | Treating NAFLD in OLETF rats with vigorous-intensity interval exercise training. | 2015 | Details |
| A21895 | 24975463 | Diabet Med | Serum fetuin-A concentration predicts glycaemic outcomes in people with prediabetes: a prospective study from eastern India. | 2014 | Details |
| A21908 | 24968737 | Endocrine | Does vitamin D improve liver enzymes, oxidative stress, and inflammatory biomarkers in adults with non-alcoholic fatty liver disease? A randomized clinical trial. | 2014 | Details |
| A21952 | 24941342 | Molecules | Standardized Salvia miltiorrhiza extract suppresses hepatic stellate cell activation and attenuates steatohepatitis induced by a methionine-choline deficient diet in mice. | 2014 | Details |
| A21980 | 24917551 | Gut | Roux-en-y gastric bypass attenuates hepatic mitochondrial dysfunction in mice with non-alcoholic steatohepatitis. | 2014 | Details |
| A22043 | 24854865 | FEBS J | Overexpression of juxtaposed with another zinc finger gene 1 reduces proinflammatory cytokine release via inhibition of stress-activated protein kinases and nuclear factor-κB. | 2014 | Details |
| A22049 | 24850609 | Georgian Med News | [Effect of gene polymorphism of PPARgamma2 regulatory proteins on the metabolic syndrome in children with nonalcoholic fatty liver disease and obesity]. | 2014 | Details |
| A22054 | 24849253 | PLoS One | Deletion of nardilysin prevents the development of steatohepatitis and liver fibrotic changes. | 2014 | Details |
| A22070 | 24841999 | Food Funct | Persimmon tannin accounts for hypolipidemic effects of persimmon through activating of AMPK and suppressing NF-κB activation and inflammatory responses in high-fat diet rats. | 2014 | Details |
| A22103 | 24819229 | Metab Syndr Relat Disord | Interrelationships of serum androgens, omental adipose tissue metabolism, and nonalcoholic fatty liver disease in obese premenopausal women. | 2014 | Details |
| A22107 | 24816278 | PLoS One | Lactoferrin dampens high-fructose corn syrup-induced hepatic manifestations of the metabolic syndrome in a murine model. | 2014 | Details |
| A22218 | 24743504 | Eur J Gastroenterol Hepatol | Pentoxifylline for the treatment of nonalcoholic fatty liver disease: a meta-analysis of randomized double-blind, placebo-controlled studies. | 2014 | Details |
| A22222 | 24742471 | J Nutr Biochem | Insight into the impact of dietary saturated fat on tissue-specific cellular processes underlying obesity-related diseases. | 2014 | Details |
| A22223 | 24741401 | Nutr Res Pract | Cordyceps militaris alleviates non-alcoholic fatty liver disease in ob/ob mice. | 2014 | Details |
| A22227 | 24739055 | Clin Exp Pharmacol Physiol | Toll-like receptor-4 signalling in the progression of non-alcoholic fatty liver disease induced by high-fat and high-fructose diet in mice. | 2014 | Details |
| A22257 | 24715054 | Neurol Sci | The association between seizure predisposition and inflammation in a rat model of fatty liver disease. | 2014 | Details |
| A22309 | 24674765 | Liver Int | Non-alcoholic steatohepatitis weakens the acute phase response to endotoxin in rats. | 2014 | Details |
| A22334 | 24653580 | Afr J Tradit Complement Altern Med | p38 MAPK signal pathway involved in anti-inflammatory effect of Chaihu-Shugan-San and Shen-ling-bai-zhu-San on hepatocyte in non-alcoholic steatohepatitis rats. | 2013 | Details |
| A22380 | 24629563 | Metabolism | Resveratrol ameliorates hepatic metaflammation and inhibits NLRP3 inflammasome activation. | 2014 | Details |
| A22400 | 24616207 | Obesity (Silver Spring) | Macrophages and fibrosis in adipose tissue are linked to liver damage and metabolic risk in obese children. | 2014 | Details |
| A22415 | 24597775 | Antioxid Redox Signal | RORα decreases oxidative stress through the induction of SOD2 and GPx1 expression and thereby protects against nonalcoholic steatohepatitis in mice. | 2014 | Details |
| A22439 | 24577062 | J Appl Physiol (1985) | Reduced hepatic eNOS phosphorylation is associated with NAFLD and type 2 diabetes progression and is prevented by daily exercise in hyperphagic OLETF rats. | 2014 | Details |
| A22443 | 24574727 | World J Gastroenterol | Effects of pentoxifylline on nonalcoholic fatty liver disease: a meta-analysis. | 2014 | Details |
| A22476 | 24529605 | J Crohns Colitis | Detection of liver injury in IBD using transient elastography. | 2014 | Details |
| A22489 | 24520264 | Exp Ther Med | Comparison between the efficacies of curcumin and puerarin in C57BL/6 mice with steatohepatitis induced by a methionine- and choline-deficient diet. | 2013 | Details |
| A22533 | 24486698 | Mol Cell Endocrinol | Nonalcoholic steatohepatitis as a novel player in metabolic syndrome-induced erectile dysfunction: an experimental study in the rabbit. | 2014 | Details |
| A22553 | 24466347 | PLoS One | Inhibitory effects of Japanese herbal medicines sho-saiko-to and juzen-taiho-to on nonalcoholic steatohepatitis in mice. | 2014 | Details |
| A22583 | 24445049 | J Nutr Biochem | Sesame oil mitigates nutritional steatohepatitis via attenuation of oxidative stress and inflammation: a tale of two-hit hypothesis. | 2013 | Details |
| A22584 | 24445047 | J Nutr Biochem | Role of immunodeficient animal models in the development of fructose induced NAFLD. | 2013 | Details |
| A22599 | 24426199 | Indian J Clin Biochem | Efficacy of Tumor Necrosis Factor and Interleukin-10 Analysis in the Follow-up of Nonalcoholic Fatty Liver Disease Progression. | 2012 | Details |
| A22625 | 24401715 | Am J Clin Nutr | Synbiotic supplementation in nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled pilot study. | 2014 | Details |
| A22631 | 24396649 | Endocrinol Metab (Seoul) | Tumor Necrosis Factor-α as a Predictor for the Development of Nonalcoholic Fatty Liver Disease: A 4-Year Follow-Up Study. | 2013 | Details |
| A22632 | 24396406 | Exp Ther Med | Effects of glutamine on oxidative stress and nuclear factor-κB expression in the livers of rats with nonalcoholic fatty liver disease. | 2013 | Details |
| A22634 | 24393106 | Antioxid Redox Signal | Mitochondrial dysfunction in obesity-associated nonalcoholic fatty liver disease: the protective effects of pomegranate with its active component punicalagin. | 2014 | Details |
| A22643 | 24388027 | Mayo Clin Proc | Drug-induced liver injury. | 2014 | Details |
| A22661 | 24377455 | Nutrition | Effects of bayberry juice on inflammatory and apoptotic markers in young adults with features of non-alcoholic fatty liver disease. | 2014 | Details |
| A22662 | 24377452 | Nutrition | Central obesity and altered peripheral adipose tissue gene expression characterize the NAFLD patient with insulin resistance: Role of nutrition and insulin challenge. | 2014 | Details |
| A22691 | 25911908 | Eksp Klin Gastroenterol | [Adipokines and liver function in patients with nonalcoholic fatty liver disease, type 2 diabetes mellitus and its combination]. | 2014 | Details |
| A22723 | 24356885 | Am J Physiol Gastrointest Liver Physiol | Therapeutic role of niacin in the prevention and regression of hepatic steatosis in rat model of nonalcoholic fatty liver disease. | 2013 | Details |
| A22730 | 24351808 | Int J Mol Sci | EZH2 down-regulation exacerbates lipid accumulation and inflammation in in vitro and in vivo NAFLD. | 2013 | Details |
| A22833 | 24275089 | Food Chem Toxicol | Monascin and ankaflavin act as natural AMPK activators with PPARα agonist activity to down-regulate nonalcoholic steatohepatitis in high-fat diet-fed C57BL/6 mice. | 2013 | Details |
| A22860 | 24273273 | Nan Fang Yi Ke Da Xue Xue Bao | [Effects of glucagon-like peptide-1 on liver oxidative stress, TNF-α and TGF-β1 in rats with non-alcoholic fatty liver disease]. | 2013 | Details |
| A22883 | 24256086 | Am J Respir Crit Care Med | Obstructive sleep apnea syndrome affects liver histology and inflammatory cell activation in pediatric nonalcoholic fatty liver disease, regardless of obesity/insulin resistance. | 2014 | Details |
| A22885 | 24254368 | Hepatology | The portal inflammatory infiltrate and ductular reaction in human nonalcoholic fatty liver disease. | 2014 | Details |
| A22946 | 24187469 | World J Gastroenterol | Effects of probiotics on nonalcoholic fatty liver disease: a meta-analysis. | 2013 | Details |
| A22975 | 24151364 | World J Gastroenterol | Nonalcoholic fatty liver disease is associated with coronary artery disease in Koreans. | 2013 | Details |
| A23012 | 24117897 | J Gastroenterol Hepatol | Effects of treatment with hydrogen sulfide on methionine-choline deficient diet-induced non-alcoholic steatohepatitis in rats. | 2014 | Details |
| A23016 | 24115128 | Hepatology | Adaptive immune responses triggered by oxidative stress contribute to hepatic inflammation in NASH. | 2014 | Details |
| A23040 | 24084392 | J Chin Med Assoc | The involvement of NLRX1 and NLRP3 in the development of nonalcoholic steatohepatitis in mice. | 2013 | Details |
| A23059 | 24073298 | World J Hepatol | Current role of fenofibrate in the prevention and management of non-alcoholic fatty liver disease. | 2013 | Details |
| A23068 | 24067262 | Ann Hepatol | Adipocytokines and cytokeratin-18 in patients with nonalcoholic fatty liver disease: Introduction of CHA index. | 2014 | Details |
| A23070 | 24066058 | PLoS One | Aldose reductase is involved in the development of murine diet-induced nonalcoholic steatohepatitis. | 2013 | Details |
| A23076 | 24064383 | Free Radic Biol Med | CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis. | 2013 | Details |
| A23089 | 24048504 | Med Mol Morphol | Linagliptin alleviates hepatic steatosis and inflammation in a mouse model of non-alcoholic steatohepatitis. | 2013 | Details |
| A23152 | 24002036 | Endocrinology | Maternal hypoxia increases the susceptibility of adult rat male offspring to high-fat diet-induced nonalcoholic fatty liver disease. | 2013 | Details |
| A23164 | 25755505 | J Clin Exp Hepatol | MicroRNAs in Liver Disease: Bench to Bedside. | 2013 | Details |
| A23180 | 23981577 | Cancer Lett | Non-alcoholic steatohepatitis and preneoplastic lesions develop in the liver of obese and hypertensive rats: suppressing effects of EGCG on the development of liver lesions. | 2013 | Details |
| A23185 | 23978414 | Food Chem Toxicol | Resveratrol modulates autophagy and NF-κB activity in a murine model for treating non-alcoholic fatty liver disease. | 2013 | Details |
| A23187 | 23976771 | JPEN J Parenter Enteral Nutr | The effect of a low fructose and low glycemic index/load (FRAGILE) dietary intervention on indices of liver function, cardiometabolic risk factors, and body composition in children and adolescents with nonalcoholic fatty liver disease (NAFLD). | 2013 | Details |
| A23189 | 23975340 | Dig Dis Sci | Cyclooxygenase-2 promotes hepatocellular apoptosis by interacting with TNF-α and IL-6 in the pathogenesis of nonalcoholic steatohepatitis in rats. | 2013 | Details |
| A23214 | 23954219 | Gene | Association between resistin +299A/A genotype and nonalcoholic fatty liver disease in Chinese patients with type 2 diabetes mellitus. | 2013 | Details |
| A23247 | 23928404 | J Hepatol | Adipose tissue and liver expression of SIRT1, 3, and 6 increase after extensive weight loss in morbid obesity. | 2013 | Details |
| A23249 | 23928105 | Metabolism | Methionine restriction prevents the progression of hepatic steatosis in leptin-deficient obese mice. | 2013 | Details |
| A23253 | 23923372 | Trop Gastroenterol | Fibrosis in non-alcoholic fatty liver disease: correlation with simple blood indices and association with tumor necrosis factor-alpha polymorphisms. | 2013 | Details |
| A23258 | 23922466 | World J Gastroenterol | Garcinia Cambogia attenuates diet-induced adiposity but exacerbates hepatic collagen accumulation and inflammation. | 2013 | Details |
| A23303 | 23883694 | J Nutr Sci Vitaminol (Tokyo) | The effect of ethyl pyruvate supplementation on rat fatty liver induced by a high-fat diet. | 2013 | Details |
| A23321 | 23872500 | Gastroenterology | No difference between high-fructose and high-glucose diets on liver triacylglycerol or biochemistry in healthy overweight men. | 2013 | Details |
| A23348 | 23851679 | Food Funct | Oat β-glucan inhibits lipopolysaccharide-induced nonalcoholic steatohepatitis in mice. | 2013 | Details |
| A23349 | 23850676 | Biochem Biophys Res Commun | Propranolol, a β-adrenoceptor antagonist, worsens liver injury in a model of non-alcoholic steatohepatitis. | 2013 | Details |
| A23376 | 23834389 | Hepatol Res | Augmented hepatic Toll-like receptors by fatty acids trigger the pro-inflammatory state of non-alcoholic fatty liver disease in mice. | 2013 | Details |
| A23381 | 23831119 | J Hepatol | Cell-specific PPARγ deficiency establishes anti-inflammatory and anti-fibrogenic properties for this nuclear receptor in non-parenchymal liver cells. | 2013 | Details |
| A23386 | 23827477 | Trends Endocrinol Metab | Non-alcoholic steatohepatitis: a microbiota-driven disease. | 2013 | Details |
| A23395 | 23816817 | Trends Mol Med | Interactions among bone, liver, and adipose tissue predisposing to diabesity and fatty liver. | 2013 | Details |
| A23400 | 23813132 | Ann Hepatol | Association of plasma visfatin with hepatic and systemic inflammation in nonalcoholic fatty liver disease. | 2013 | Details |
| A23433 | 23790128 | J Hum Nutr Diet | Hypoadiponectinaemia in nonalcoholic fatty liver disease obese women is associated with infrequent intake of dietary sucrose and fatty foods. | 2013 | Details |
| A23479 | 23744740 | Am J Physiol Gastrointest Liver Physiol | CTRP3 attenuates diet-induced hepatic steatosis by regulating triglyceride metabolism. | 2013 | Details |
| A23491 | 23733885 | J Lipid Res | Deficiency of liver Comparative Gene Identification-58 causes steatohepatitis and fibrosis in mice. | 2013 | Details |
| A23495 | 23727306 | J Hepatol | Dendritic cells in liver injury and fibrosis: shortcomings and promises. | 2013 | Details |
| A23510 | 25755488 | J Clin Exp Hepatol | Gut-liver axis: role of inflammasomes. | 2013 | Details |
| A23522 | 23711137 | Am J Chin Med | Triterpenoid-rich fraction from Ilex hainanensis Merr. attenuates non-alcoholic fatty liver disease induced by high fat diet in rats. | 2013 | Details |
| A23531 | 23703665 | Hepatology | Advanced glycation endproducts induce fibrogenic activity in nonalcoholic steatohepatitis by modulating TNF-α-converting enzyme activity in mice. | 2013 | Details |
| A23532 | 23703580 | Hepatology | Hepatoprotective effects of the dual peroxisome proliferator-activated receptor alpha/delta agonist, GFT505, in rodent models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. | 2013 | Details |
| A23541 | 23697659 | Antioxid Redox Signal | A novel antihypoglycemic role of inducible nitric oxide synthase in liver inflammatory response induced by dietary cholesterol and endotoxemia. | 2013 | Details |
| A23572 | 23665282 | J Hepatol | Food-derived peroxidized fatty acids may trigger hepatic inflammation: a novel hypothesis to explain steatohepatitis. | 2013 | Details |
| A23627 | 23618531 | J Nutr Biochem | Polychlorinated biphenyl 153 is a diet-dependent obesogen that worsens nonalcoholic fatty liver disease in male C57BL6/J mice. | 2013 | Details |
| A23633 | 23611112 | Clin Exp Pharmacol Physiol | A high-fat diet and multiple administration of carbon tetrachloride induces liver injury and pathological features associated with non-alcoholic steatohepatitis in mice. | 2013 | Details |
| A23658 | 23592667 | Obesity (Silver Spring) | Accuracy of prediction scores and novel biomarkers for predicting nonalcoholic fatty liver disease in obese children. | 2013 | Details |
| A23681 | 23567086 | J Hepatol | Decoding cell death signals in liver inflammation. | 2013 | Details |
| A23698 | 23557869 | J Hepatol | Marked 25-hydroxyvitamin D deficiency is associated with poor prognosis in patients with alcoholic liver disease. | 2013 | Details |
| A23721 | 23537653 | Biochem Biophys Res Commun | Hydrogen peroxide impairs autophagic flux in a cell model of nonalcoholic fatty liver disease. | 2013 | Details |
| A23743 | 23515587 | Eur J Nutr | Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in non-alcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/Akt/FoxO1, and NF-kappa B pathways. | 2013 | Details |
| A23760 | 23505183 | Obesity (Silver Spring) | Retinol binding protein-4 circulating levels were higher in nonalcoholic fatty liver disease vs. histologically normal liver from morbidly obese women. | 2013 | Details |
| A23783 | 23483818 | World J Gastroenterol | From fatty liver to fibrosis: a tale of "second hit". | 2013 | Details |
| A23786 | 23482247 | World J Gastroenterol | Fructose as a key player in the development of fatty liver disease. | 2013 | Details |
| A23827 | 25755466 | J Clin Exp Hepatol | Patients with Nonalcoholic Fatty Liver Disease (NAFLD) have Higher Oxidative Stress in Comparison to Chronic Viral Hepatitis. | 2012 | Details |
| A23853 | 23426790 | Int J Mol Med | Anti-inflammatory effects of total alkaloids from Rubus alceifolius Poir [corrected]. on non-alcoholic fatty liver disease through regulation of the NF-κB pathway. | 2013 | Details |
| A23920 | 23389749 | Food Funct | Hibiscus sabdariffa L. aqueous extract attenuates hepatic steatosis through down-regulation of PPAR-γ and SREBP-1c in diet-induced obese mice. | 2013 | Details |
| A23962 | 23348005 | Toxicol In Vitro | Quercetin ameliorate insulin resistance and up-regulates cellular antioxidants during oleic acid induced hepatic steatosis in HepG2 cells. | 2013 | Details |
| A23999 | 23315950 | Hepatology | Maternal obesity programs offspring nonalcoholic fatty liver disease by innate immune dysfunction in mice. | 2013 | Details |
| A24078 | 23258548 | Mol Pharmacol | 5-cholesten-3β,25-diol 3-sulfate decreases lipid accumulation in diet-induced nonalcoholic fatty liver disease mouse model. | 2012 | Details |